# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DLIC PF05783.6 GAP82325.1 - 6.9e-32 110.7 0.0 3.9e-31 108.2 0.0 2.2 3 1 0 3 3 3 1 Dynein light intermediate chain (DLIC) Thioredox_DsbH PF03190.10 GAP82326.1 - 7.7e-50 168.7 0.0 1.8e-49 167.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 GAP82326.1 - 0.00033 20.6 0.0 0.00068 19.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like GlcNAc_2-epim PF07221.6 GAP82326.1 - 0.0039 16.2 0.0 0.007 15.4 0.0 1.3 1 0 0 1 1 1 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_76 PF03663.9 GAP82326.1 - 0.0076 15.6 1.6 0.019 14.3 0.6 1.9 2 1 0 2 2 2 1 Glycosyl hydrolase family 76 Sigma70_r4 PF04545.11 GAP82326.1 - 0.089 12.1 0.3 0.23 10.7 0.2 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 FAM196 PF15265.1 GAP82328.1 - 2.5 7.2 14.1 3.3 6.8 9.7 1.1 1 0 0 1 1 1 0 FAM196 family DUF605 PF04652.11 GAP82328.1 - 4.1 6.7 23.5 5.3 6.3 16.3 1.1 1 0 0 1 1 1 0 Vta1 like Ank_2 PF12796.2 GAP82329.1 - 7.4e-60 199.2 8.6 1.3e-19 70.3 0.0 5.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAP82329.1 - 5e-52 171.2 13.9 4.4e-06 26.2 0.1 9.7 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 GAP82329.1 - 4.1e-48 160.9 8.2 2.9e-12 46.7 0.1 7.9 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP82329.1 - 4.8e-41 134.6 5.3 0.00028 20.8 0.0 9.7 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 GAP82329.1 - 1.6e-34 117.1 13.4 6.6e-09 35.7 0.2 6.6 4 2 2 6 6 6 5 Ankyrin repeats (many copies) CorA PF01544.13 GAP82329.1 - 6.8e-12 45.0 0.6 4.8e-11 42.2 0.0 2.3 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein EMP70 PF02990.11 GAP82329.1 - 0.081 11.3 1.1 0.12 10.8 0.8 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 Lipase_GDSL_2 PF13472.1 GAP82330.1 - 1.3e-14 54.7 0.0 2.2e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAP82330.1 - 5.7e-10 39.4 0.0 1.1e-09 38.4 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 GAP82330.1 - 0.00079 19.2 0.2 0.0018 18.0 0.0 1.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family FAD_binding_3 PF01494.14 GAP82333.1 - 2.3e-68 230.8 0.0 3e-68 230.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Tannase PF07519.6 GAP82334.1 - 1.1e-87 294.7 0.5 2.5e-87 293.5 0.4 1.5 1 1 0 1 1 1 1 Tannase and feruloyl esterase MFS_1 PF07690.11 GAP82335.1 - 2.2e-13 49.6 23.8 3.1e-13 49.1 16.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 GAP82335.1 - 0.066 13.0 0.4 0.066 13.0 0.3 2.8 3 0 0 3 3 3 0 MFS_1 like family Sulfatase PF00884.18 GAP82336.1 - 2.4e-59 201.0 0.9 3.1e-59 200.6 0.6 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 GAP82336.1 - 0.13 11.5 5.9 1.1 8.4 4.1 2.0 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase MFS_1 PF07690.11 GAP82337.1 - 1.8e-40 138.7 41.4 1.8e-40 138.7 28.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP82337.1 - 8.1e-08 31.2 6.4 8.1e-08 31.2 4.4 3.9 3 1 0 4 4 4 3 Sugar (and other) transporter OCD_Mu_crystall PF02423.10 GAP82338.1 - 9.3e-12 44.3 0.0 1.3e-10 40.5 0.0 2.5 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 GAP82338.1 - 8e-07 29.2 0.0 2.2e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 GAP82339.1 - 5e-41 140.7 3.5 6e-41 140.5 2.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAP82339.1 - 1.9e-07 31.1 0.0 0.0014 18.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP82339.1 - 2e-07 30.9 0.1 6.6e-07 29.2 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAP82339.1 - 5e-06 26.7 0.0 0.00011 22.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAP82339.1 - 0.00014 21.6 0.1 0.026 14.2 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 GAP82339.1 - 0.00053 18.5 0.4 0.01 14.3 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 GAP82339.1 - 0.001 17.9 4.4 0.006 15.4 3.0 2.0 1 1 0 1 1 1 1 FAD binding domain ThiF PF00899.16 GAP82339.1 - 0.0019 18.0 0.0 0.0045 16.8 0.0 1.6 1 0 0 1 1 1 1 ThiF family FAD_binding_3 PF01494.14 GAP82339.1 - 0.0037 16.3 0.2 0.01 14.9 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 GAP82339.1 - 0.0073 15.2 0.1 1.1 7.9 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox PF00070.22 GAP82339.1 - 0.015 15.6 0.0 0.064 13.6 0.0 2.1 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 GAP82339.1 - 0.017 14.5 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Amino_oxidase PF01593.19 GAP82339.1 - 0.018 14.0 0.2 0.72 8.8 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase TrkA_N PF02254.13 GAP82339.1 - 0.022 14.7 0.0 0.065 13.2 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain Thi4 PF01946.12 GAP82339.1 - 0.044 12.8 0.7 0.11 11.5 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.15 GAP82339.1 - 0.1 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 GAP82339.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.20 GAP82340.1 - 2.7e-29 102.1 0.0 8.9e-29 100.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP82340.1 - 5e-10 38.8 0.0 0.00022 20.4 0.0 2.8 2 2 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 GAP82340.1 - 0.061 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Acyltransferase PF01553.16 GAP82341.1 - 0.025 14.0 0.0 0.082 12.3 0.0 1.8 1 1 0 1 1 1 0 Acyltransferase ILVD_EDD PF00920.16 GAP82342.1 - 2.4e-205 682.8 0.3 2.8e-205 682.6 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family GTP_EFTU_D4 PF14578.1 GAP82342.1 - 0.12 11.9 4.2 6.5 6.4 0.0 3.4 3 0 0 3 3 3 0 Elongation factor Tu domain 4 HTH_25 PF13413.1 GAP82342.1 - 0.15 11.7 0.7 8.6 6.0 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain Aa_trans PF01490.13 GAP82343.1 - 5.8e-23 81.0 26.6 1.4e-22 79.7 18.2 1.6 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Amino_oxidase PF01593.19 GAP82345.1 - 4.5e-48 164.4 0.0 5.9e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HNH_2 PF13391.1 GAP82346.1 - 6.7e-11 41.8 0.0 1.3e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease COesterase PF00135.23 GAP82347.1 - 4.4e-62 210.5 2.7 2.2e-61 208.1 1.9 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAP82347.1 - 7.4e-14 51.8 0.2 2.6e-13 50.0 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAP82347.1 - 0.00043 19.5 1.0 0.00077 18.7 0.7 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2235 PF09994.4 GAP82347.1 - 0.036 13.4 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 GAP82347.1 - 0.036 13.8 0.1 0.059 13.1 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DNA_pol_A PF00476.15 GAP82349.1 - 5.4e-102 341.2 0.0 8e-102 340.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A MFS_1 PF07690.11 GAP82350.1 - 7.2e-39 133.4 50.9 7.2e-39 133.4 35.3 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 GAP82351.1 - 3.4e-19 69.6 0.1 4.4e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAP82351.1 - 6.9e-19 67.4 0.0 1.2e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 GAP82351.1 - 1.3e-15 57.4 0.0 2.1e-15 56.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP82351.1 - 5.4e-06 26.1 0.0 1.3e-05 24.8 0.0 1.6 1 1 0 2 2 2 1 alpha/beta hydrolase fold DUF1749 PF08538.5 GAP82351.1 - 0.00035 19.5 0.0 0.00051 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Lipase_3 PF01764.20 GAP82351.1 - 0.013 15.0 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.15 GAP82351.1 - 0.017 14.5 0.2 0.035 13.5 0.1 1.4 1 1 0 1 1 1 0 Putative esterase Chlorophyllase2 PF12740.2 GAP82351.1 - 0.017 14.0 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.8 GAP82351.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.15 GAP82351.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.6 1 1 0 1 1 1 0 Thioesterase domain MFS_1 PF07690.11 GAP82353.1 - 1.5e-09 37.0 17.9 1.8e-09 36.7 12.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Wzy_C PF04932.10 GAP82353.1 - 0.35 10.6 4.0 0.57 9.9 2.7 1.4 1 1 0 1 1 1 0 O-Antigen ligase p450 PF00067.17 GAP82354.1 - 6.5e-58 196.3 0.0 9e-58 195.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ORC6 PF05460.8 GAP82355.1 - 0.21 10.6 13.1 0.35 9.9 9.1 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Pol_alpha_B_N PF08418.5 GAP82355.1 - 0.38 10.2 11.6 0.63 9.5 8.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Dicty_REP PF05086.7 GAP82355.1 - 5.5 4.6 7.3 7.4 4.1 5.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Abhydrolase_5 PF12695.2 GAP82358.1 - 1.7e-13 50.5 0.1 2.8e-13 49.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP82358.1 - 4.2e-13 49.7 2.2 6.7e-13 49.0 1.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 GAP82358.1 - 2.1e-06 27.4 0.3 3.4e-06 26.7 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAP82358.1 - 0.0012 18.0 1.3 0.027 13.7 0.0 2.7 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydro_lipase PF04083.11 GAP82358.1 - 0.021 14.1 0.0 0.051 12.9 0.0 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 GAP82358.1 - 0.065 12.7 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ank_2 PF12796.2 GAP82359.1 - 6.3e-34 116.1 0.0 1.7e-08 34.6 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAP82359.1 - 1.5e-26 90.8 0.4 4.6e-05 23.0 0.0 7.0 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 GAP82359.1 - 2.9e-22 78.1 0.8 6.4e-08 32.6 0.1 5.4 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAP82359.1 - 7.6e-21 74.0 0.2 3.5e-05 24.1 0.0 5.0 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP82359.1 - 3.2e-18 63.9 1.3 0.0037 17.3 0.0 7.3 7 0 0 7 7 7 3 Ankyrin repeat NACHT PF05729.7 GAP82359.1 - 0.0012 18.5 0.0 0.0036 16.9 0.0 1.9 1 1 0 1 1 1 1 NACHT domain FCH PF00611.18 GAP82359.1 - 0.0049 17.0 0.4 0.0049 17.0 0.3 2.3 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain AAA_16 PF13191.1 GAP82359.1 - 0.034 14.1 0.2 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 GAP82359.1 - 0.035 14.2 0.0 0.089 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Syntaxin PF00804.20 GAP82359.1 - 8.1 6.6 8.0 1 9.5 2.1 2.1 2 1 0 2 2 2 0 Syntaxin Glyco_hydro_3 PF00933.16 GAP82360.1 - 8.9e-14 51.1 0.1 6.8e-13 48.2 0.0 2.0 1 1 1 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Sas10_Utp3 PF04000.10 GAP82361.1 - 4.7e-18 65.1 1.3 9.8e-18 64.1 0.3 2.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Nop53 PF07767.6 GAP82361.1 - 0.082 11.8 21.5 0.11 11.5 14.9 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Med19 PF10278.4 GAP82361.1 - 0.17 11.5 17.6 0.26 10.9 12.2 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Peptidase_C37 PF05416.7 GAP82361.1 - 0.18 10.0 4.9 0.24 9.6 3.4 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase GAGA_bind PF06217.7 GAP82361.1 - 0.29 11.0 9.2 0.36 10.7 6.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2201_N PF13203.1 GAP82361.1 - 0.52 9.4 5.7 0.71 8.9 4.0 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 GAP82361.1 - 1.4 6.8 15.4 1.9 6.4 10.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_polI_A34 PF08208.6 GAP82361.1 - 1.5 8.4 22.2 2.4 7.8 15.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Hid1 PF12722.2 GAP82361.1 - 2.9 5.4 8.4 3.5 5.1 5.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.7 GAP82361.1 - 3 7.6 14.2 3.8 7.3 9.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ApbA PF02558.11 GAP82362.1 - 2.3e-10 40.1 0.0 5.2e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 GAP82362.1 - 3e-08 33.7 0.0 6.9e-08 32.5 0.0 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal dsDNA_bind PF01984.15 GAP82363.1 - 3.4e-32 110.6 13.7 4.1e-32 110.3 9.5 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain HWE_HK PF07536.9 GAP82363.1 - 0.17 12.3 4.8 0.11 12.9 1.0 2.3 1 1 0 2 2 2 0 HWE histidine kinase Prok-TraM PF09228.5 GAP82363.1 - 0.25 11.5 2.6 0.28 11.3 0.3 2.0 1 1 1 2 2 2 0 Prokaryotic Transcriptional repressor TraM Rap1_C PF11626.3 GAP82363.1 - 0.43 10.4 3.4 0.91 9.4 0.3 2.4 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Alb1 PF09135.6 GAP82363.1 - 2 9.0 7.1 1.6 9.3 0.8 2.2 1 1 1 2 2 2 0 Alb1 APC_CDC26 PF10471.4 GAP82363.1 - 8.4 7.2 8.6 1.7 9.3 2.9 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Yae1_N PF09811.4 GAP82364.1 - 6.4e-12 44.8 3.2 7.2e-12 44.6 1.6 1.6 1 1 0 1 1 1 1 Essential protein Yae1, N terminal Methyltransf_6 PF03737.10 GAP82365.1 - 4.3e-30 104.6 0.0 5.3e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase MFS_1 PF07690.11 GAP82366.1 - 2.1e-30 105.6 43.1 9.2e-30 103.5 29.9 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAP82366.1 - 3.3e-10 38.7 19.4 4.5e-10 38.3 13.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1118 PF06549.7 GAP82366.1 - 4.9 7.3 7.2 0.31 11.2 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1118) Asp PF00026.18 GAP82367.1 - 4.6e-65 219.9 0.5 6e-65 219.5 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAP82367.1 - 2.9e-08 33.8 0.0 1.9e-06 27.8 0.0 3.3 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 GAP82367.1 - 0.0028 18.1 2.5 3.1 8.3 0.2 4.0 3 2 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 GAP82367.1 - 0.085 12.4 0.0 3.2 7.2 0.0 2.2 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal RRM_6 PF14259.1 GAP82368.1 - 1.2e-11 44.4 0.0 6.6e-05 22.8 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.18 GAP82368.1 - 1.5e-09 37.5 0.9 3.3e-09 36.3 0.6 1.7 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.17 GAP82368.1 - 5.3e-09 35.5 0.1 0.0027 17.3 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.13 GAP82368.1 - 2.9e-07 29.4 2.9 5.1e-07 28.6 2.0 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_5 PF13893.1 GAP82368.1 - 6.2e-07 29.1 0.0 0.00014 21.6 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 GAP82368.1 - 9.2e-05 22.2 2.4 0.00012 21.8 0.3 2.3 2 0 0 2 2 2 1 DExH-box splicing factor binding site RED_N PF07808.8 GAP82368.1 - 0.01 15.0 0.1 0.01 15.0 0.1 2.0 3 0 0 3 3 3 0 RED-like protein N-terminal region zf-met PF12874.2 GAP82368.1 - 3.2 8.1 5.9 0.64 10.3 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 GAP82368.1 - 6.2 7.4 14.2 0.24 11.8 1.2 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger AMP-binding PF00501.23 GAP82369.1 - 5e-86 288.7 0.0 8.4e-86 287.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 GAP82369.1 - 1.1e-68 231.5 0.0 2.1e-68 230.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAP82369.1 - 7.9e-59 199.5 0.0 1.7e-58 198.4 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 GAP82369.1 - 1.6e-54 184.3 2.2 5.8e-54 182.4 0.1 2.5 2 0 0 2 2 2 1 KR domain Condensation PF00668.15 GAP82369.1 - 3.2e-47 160.8 0.0 5.4e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.1 GAP82369.1 - 4.8e-47 160.5 0.0 9e-47 159.6 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 GAP82369.1 - 7.6e-44 149.5 0.9 2.1e-42 144.8 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAP82369.1 - 1.6e-30 105.3 0.0 6.9e-30 103.3 0.0 2.2 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 GAP82369.1 - 5.2e-23 81.2 0.0 1.5e-22 79.7 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 GAP82369.1 - 1.6e-20 73.3 0.0 4.3e-20 72.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 GAP82369.1 - 4.9e-16 58.7 1.9 4.1e-08 33.3 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 GAP82369.1 - 1.6e-12 48.0 0.0 9.5e-12 45.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP82369.1 - 1e-11 44.7 0.0 3.4e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 GAP82369.1 - 3.2e-11 43.3 0.0 1.2e-10 41.5 0.0 2.0 1 0 0 1 1 1 1 HxxPF-repeated domain Epimerase PF01370.16 GAP82369.1 - 7.3e-11 41.9 0.0 2.6e-05 23.7 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.7 GAP82369.1 - 2e-10 41.0 0.0 5.6e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP82369.1 - 3.8e-10 39.5 0.0 9.8e-10 38.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP82369.1 - 2e-06 28.1 0.0 1.7e-05 25.0 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain 3Beta_HSD PF01073.14 GAP82369.1 - 6.1e-05 21.8 0.1 0.0054 15.4 0.0 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.13 GAP82369.1 - 0.00063 18.9 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 GAP82369.1 - 0.00093 19.2 0.0 0.0028 17.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 GAP82369.1 - 0.003 16.5 0.0 0.0067 15.4 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain RrnaAD PF00398.15 GAP82369.1 - 0.011 14.7 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.4 GAP82369.1 - 0.15 11.5 0.0 0.4 10.1 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_28 PF02636.12 GAP82369.1 - 0.22 10.9 0.0 0.41 9.9 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase N6-adenineMlase PF10237.4 GAP82369.1 - 0.42 10.2 0.0 1.4 8.5 0.0 1.9 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase AATase PF07247.7 GAP82369.1 - 1.7 7.0 0.0 2.9 6.3 0.0 1.2 1 0 0 1 1 1 0 Alcohol acetyltransferase p450 PF00067.17 GAP82370.1 - 1.2e-23 83.4 0.0 2.1e-23 82.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 HSP90 PF00183.13 GAP82370.1 - 0.036 12.4 0.0 0.058 11.7 0.0 1.2 1 0 0 1 1 1 0 Hsp90 protein Methyltransf_2 PF00891.13 GAP82371.1 - 1.3e-23 83.4 0.0 1.5e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 GAP82371.1 - 0.00042 20.0 0.0 0.00066 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Sulfatase PF00884.18 GAP82371.1 - 0.02 14.1 0.2 0.03 13.5 0.1 1.3 1 0 0 1 1 1 0 Sulfatase TraU PF06834.6 GAP82371.1 - 0.063 12.3 0.1 0.091 11.8 0.0 1.2 1 0 0 1 1 1 0 TraU protein MFS_1 PF07690.11 GAP82372.1 - 3.1e-35 121.5 49.8 3.1e-35 121.5 33.1 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP82372.1 - 3.1e-10 39.2 8.7 3.1e-10 39.2 6.0 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.15 GAP82372.1 - 0.19 9.7 14.7 0.18 9.8 0.6 3.0 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.17 GAP82373.1 - 1.2e-20 73.5 0.0 3.4e-20 72.0 0.0 1.7 3 0 0 3 3 3 1 Cytochrome P450 Methyltransf_2 PF00891.13 GAP82374.1 - 3.4e-23 82.1 0.0 4.9e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Herpes_gE PF02480.11 GAP82375.1 - 0.0036 15.6 0.2 0.0036 15.6 0.2 2.1 1 1 1 2 2 2 1 Alphaherpesvirus glycoprotein E DAG1 PF05454.6 GAP82375.1 - 0.0067 15.6 0.1 0.011 15.0 0.1 1.4 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) EphA2_TM PF14575.1 GAP82375.1 - 0.079 13.3 0.8 0.21 12.0 0.0 2.1 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF2762 PF10960.3 GAP82375.1 - 0.12 12.0 0.2 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) CcmD PF04995.9 GAP82375.1 - 3.7 7.3 7.1 0.15 11.8 0.9 1.7 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) MFS_1 PF07690.11 GAP82376.1 - 1.3e-46 158.9 25.8 1.3e-46 158.9 17.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP82376.1 - 1.4e-11 43.7 12.4 1.4e-11 43.7 8.6 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 GAP82376.1 - 4e-05 22.0 5.7 6.5e-05 21.3 4.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 GAP82376.1 - 4.1e-05 22.1 7.2 4.1e-05 22.1 5.0 3.3 2 2 2 4 4 4 1 MFS/sugar transport protein MFS_3 PF05977.8 GAP82376.1 - 0.00017 19.8 4.2 0.00017 19.8 2.9 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector GMC_oxred_N PF00732.14 GAP82378.1 - 1.1e-15 57.5 0.0 1.2e-15 57.5 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 GAP82378.1 - 5.9e-06 25.4 0.2 8.5e-06 24.9 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 GAP82378.1 - 0.00018 20.5 0.1 0.0012 17.7 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 GAP82378.1 - 0.00097 17.8 0.4 0.0014 17.3 0.3 1.2 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_8 PF13450.1 GAP82378.1 - 0.004 17.1 0.2 0.011 15.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAP82378.1 - 0.0065 15.5 0.2 0.0065 15.5 0.1 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 GAP82378.1 - 0.012 15.5 0.2 0.012 15.4 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAP82378.1 - 0.024 13.5 0.1 0.035 12.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 GAP82378.1 - 0.11 10.9 0.4 0.16 10.4 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein ThiF PF00899.16 GAP82378.1 - 0.12 12.1 0.2 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 ThiF family FAD_binding_3 PF01494.14 GAP82378.1 - 0.14 11.2 0.1 0.18 10.8 0.1 1.1 1 0 0 1 1 1 0 FAD binding domain Abhydrolase_5 PF12695.2 GAP82378.1 - 0.31 10.7 2.2 5.4 6.7 1.5 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.11 GAP82380.1 - 1.8e-44 151.8 47.3 5.1e-44 150.4 32.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAP82380.1 - 9.8e-18 63.6 18.2 9.8e-18 63.6 12.6 1.9 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 GAP82381.1 - 3.4e-32 111.5 0.0 9.5e-30 103.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Methyltransf_2 PF00891.13 GAP82382.1 - 3.2e-34 118.2 0.0 9e-34 116.7 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 GAP82382.1 - 3.8e-05 24.2 0.0 8.6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Aminotran_1_2 PF00155.16 GAP82383.1 - 1.2e-46 159.2 0.0 1.8e-46 158.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAP82383.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase AMP-binding PF00501.23 GAP82384.1 - 4.1e-58 196.7 0.0 6.3e-58 196.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 GAP82384.1 - 1.1e-23 84.6 0.9 4.6e-21 76.0 0.3 3.0 2 1 0 2 2 2 2 Thioesterase domain PP-binding PF00550.20 GAP82384.1 - 2.6e-10 40.4 0.2 7.1e-10 39.0 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 GAP82384.1 - 0.0004 20.3 5.2 0.0012 18.7 3.6 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family GH3 PF03321.8 GAP82384.1 - 0.02 13.4 0.1 0.048 12.1 0.0 1.5 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Hjc PF01870.13 GAP82384.1 - 0.034 13.7 0.0 0.086 12.4 0.0 1.7 1 0 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) Abhydrolase_5 PF12695.2 GAP82384.1 - 0.061 13.0 0.1 0.18 11.5 0.1 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family HSP90 PF00183.13 GAP82385.1 - 8.6e-44 149.8 24.5 1.1e-43 149.4 17.0 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 GAP82385.1 - 1.3e-12 47.5 0.1 1.3e-12 47.5 0.1 2.3 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 GAP82385.1 - 4.5e-12 45.6 0.0 6.9e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1510 PF07423.6 GAP82385.1 - 0.22 10.8 16.8 0.32 10.3 11.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PVL_ORF50 PF07768.6 GAP82385.1 - 0.22 11.5 8.8 0.29 11.1 5.3 1.7 1 1 0 1 1 1 0 PVL ORF-50-like family DUF2606 PF10794.4 GAP82385.1 - 0.34 10.3 4.2 6.5 6.1 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2606) Pox_P35 PF03213.9 GAP82385.1 - 1.5 7.7 5.7 2.4 7.0 3.5 1.6 2 0 0 2 2 2 0 Poxvirus P35 protein CDC45 PF02724.9 GAP82385.1 - 2.3 6.1 12.2 3.1 5.7 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4337 PF14235.1 GAP82385.1 - 6.1 6.6 7.3 11 5.8 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) HSP90 PF00183.13 GAP82387.1 - 2.9e-147 491.2 14.5 3.3e-147 491.1 10.0 1.0 1 0 0 1 1 1 1 Hsp90 protein PhoU PF01895.14 GAP82387.1 - 0.04 14.3 0.3 0.04 14.3 0.2 2.6 3 0 0 3 3 3 0 PhoU domain TPK_catalytic PF04263.11 GAP82387.1 - 0.05 13.1 0.3 0.1 12.1 0.2 1.5 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain DUF1676 PF07898.8 GAP82387.1 - 0.16 12.2 3.2 0.11 12.7 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Cas_Cmr5 PF09701.5 GAP82387.1 - 2.2 8.4 5.7 47 4.1 0.0 3.4 2 2 1 3 3 3 0 CRISPR-associated protein (Cas_Cmr5) Peptidase_M28 PF04389.12 GAP82389.1 - 1.7e-29 102.8 0.1 4e-29 101.6 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 p450 PF00067.17 GAP82390.1 - 1e-27 96.8 0.0 1.7e-26 92.8 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 GAP82392.1 - 2.2e-48 164.9 0.0 2.9e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sec34 PF04136.10 GAP82392.1 - 0.068 12.8 0.0 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 Sec34-like family LMWPc PF01451.16 GAP82394.1 - 5.3e-35 120.7 0.0 6.2e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Pkinase PF00069.20 GAP82395.1 - 5.3e-70 235.5 0.0 6.4e-70 235.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP82395.1 - 2.3e-31 108.7 0.0 6e-31 107.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAP82395.1 - 0.019 14.7 0.1 0.069 12.8 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 GAP82395.1 - 0.094 11.7 0.1 0.26 10.3 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3455 PF11937.3 GAP82396.1 - 5.6e-24 85.0 0.0 7.6e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) MPC PF03650.8 GAP82397.1 - 9.8e-43 144.9 0.6 1.3e-42 144.5 0.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) SURF1 PF02104.10 GAP82398.1 - 2.5e-57 194.1 1.2 7.1e-56 189.3 0.9 2.1 1 1 0 1 1 1 1 SURF1 family PilM PF07419.7 GAP82398.1 - 0.17 11.3 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 PilM CAF-1_p150 PF11600.3 GAP82398.1 - 0.4 10.0 2.9 0.56 9.5 2.0 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Dicty_REP PF05086.7 GAP82398.1 - 0.75 7.4 1.5 0.96 7.1 1.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CENP-T PF15511.1 GAP82399.1 - 3.8e-107 359.1 19.5 6.4e-107 358.3 13.5 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 GAP82399.1 - 7.4e-09 35.6 0.1 1.4e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 GAP82399.1 - 1e-05 25.5 0.0 1.9e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAP82399.1 - 7.1e-05 22.8 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 GAP82399.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Ebola_NP PF05505.7 GAP82399.1 - 9.4 4.1 8.1 2.5 6.0 1.0 2.1 2 0 0 2 2 2 0 Ebola nucleoprotein p450 PF00067.17 GAP82401.1 - 2.4e-18 65.9 0.0 3.6e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.8 GAP82402.1 - 8e-20 71.0 0.0 1.1e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAP82402.1 - 1.9e-14 54.0 0.1 2.6e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding p450 PF00067.17 GAP82404.1 - 7.5e-54 182.9 0.0 1e-53 182.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Herpes_LMP1 PF05297.6 GAP82405.1 - 3.7 6.3 6.3 6.7 5.5 4.4 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) MFS_1 PF07690.11 GAP82406.1 - 0.0092 14.7 1.4 0.011 14.4 1.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2098 PF09871.4 GAP82407.1 - 0.096 12.6 0.3 0.15 12.0 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) Zip PF02535.17 GAP82408.1 - 7.9e-27 94.0 48.3 4.1e-13 49.0 3.9 4.4 4 1 1 5 5 5 3 ZIP Zinc transporter Microvir_lysis PF04517.7 GAP82408.1 - 0.094 12.4 0.2 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Microvirus lysis protein (E), C terminus Fe-ADH PF00465.14 GAP82410.1 - 1.4e-63 214.7 0.4 1.7e-63 214.4 0.3 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 GAP82410.1 - 1.9e-06 27.3 0.6 5.4e-05 22.6 0.1 2.3 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 GAP82410.1 - 0.076 11.9 0.1 0.15 10.9 0.1 1.4 1 0 0 1 1 1 0 3-dehydroquinate synthase HET PF06985.6 GAP82411.1 - 2.5e-32 111.9 0.0 4.8e-32 111.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 GAP82412.1 - 6.2e-11 41.9 0.0 1.1e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP82412.1 - 0.0012 17.9 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAP82412.1 - 0.024 14.3 0.0 0.14 11.8 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-MYND PF01753.13 GAP82413.1 - 2.4e-08 33.7 13.6 5.2e-08 32.6 9.4 1.6 1 0 0 1 1 1 1 MYND finger SET PF00856.23 GAP82413.1 - 2.5e-07 31.1 0.3 4.5e-07 30.3 0.2 1.4 1 0 0 1 1 1 1 SET domain UBX PF00789.15 GAP82414.1 - 3.6e-09 36.5 0.0 7.1e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 UBX domain Mucin PF01456.12 GAP82414.1 - 0.0029 17.3 13.7 0.0067 16.2 4.1 2.4 2 0 0 2 2 2 2 Mucin-like glycoprotein CDC27 PF09507.5 GAP82414.1 - 0.2 10.8 14.5 0.26 10.4 10.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TFIIA PF03153.8 GAP82414.1 - 0.23 11.3 10.7 0.34 10.7 7.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CAF-1_p150 PF11600.3 GAP82414.1 - 0.26 10.6 21.5 0.36 10.1 14.9 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MRP-S31 PF15433.1 GAP82414.1 - 0.4 10.0 15.0 0.57 9.5 10.4 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Amidase PF01425.16 GAP82415.1 - 2.4e-72 244.2 0.4 8.4e-67 225.9 0.0 2.4 2 1 1 3 3 3 2 Amidase Amidase PF01425.16 GAP82416.1 - 6.4e-20 71.4 4.2 1e-19 70.7 1.6 1.8 2 0 0 2 2 2 1 Amidase DUF3404 PF11884.3 GAP82416.1 - 0.033 13.0 0.0 0.058 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) p450 PF00067.17 GAP82419.1 - 1.6e-27 96.1 0.0 2.9e-26 92.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Porphobil_deam PF01379.15 GAP82420.1 - 3.4e-05 22.8 0.1 3.7e-05 22.7 0.0 1.0 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain SSDP PF04503.8 GAP82420.1 - 0.022 14.5 0.5 0.022 14.5 0.3 1.0 1 0 0 1 1 1 0 Single-stranded DNA binding protein, SSDP Methyltransf_33 PF10017.4 GAP82423.1 - 3.7e-24 85.0 0.3 3.3e-23 81.9 0.1 2.1 2 0 0 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent Abhydrolase_6 PF12697.2 GAP82427.1 - 0.013 15.3 0.0 0.016 15.1 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.9 GAP82427.1 - 0.073 12.3 0.0 0.082 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) EHN PF06441.7 GAP82427.1 - 0.16 11.8 0.0 0.5 10.3 0.0 1.7 2 0 0 2 2 2 0 Epoxide hydrolase N terminus CorA PF01544.13 GAP82429.1 - 4.5e-08 32.4 0.3 6.2e-08 32.0 0.2 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1469 PF07332.6 GAP82429.1 - 0.058 13.1 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Pkinase PF00069.20 GAP82430.1 - 0.0052 15.9 0.0 0.009 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Phos_pyr_kin PF08543.7 GAP82431.1 - 2.8e-10 39.8 0.2 9.3e-10 38.1 0.0 2.0 3 0 0 3 3 3 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 GAP82431.1 - 1.8e-08 33.8 4.5 7.8e-08 31.7 0.3 3.0 2 1 0 2 2 2 1 pfkB family carbohydrate kinase zf-C2H2_4 PF13894.1 GAP82432.1 - 0.0013 18.9 15.2 0.1 12.9 0.4 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 GAP82432.1 - 0.068 13.5 14.4 0.13 12.6 0.6 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zinc_ribbon_2 PF13240.1 GAP82432.1 - 0.083 12.4 3.2 0.64 9.5 0.1 3.6 4 0 0 4 4 4 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 GAP82432.1 - 0.2 11.6 1.7 1.1 9.2 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-Di19 PF05605.7 GAP82432.1 - 0.26 11.4 11.4 0.055 13.6 2.8 2.5 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-ribbon_3 PF13248.1 GAP82432.1 - 2.7 7.2 6.9 1 8.6 0.3 3.0 3 0 0 3 3 3 0 zinc-ribbon domain Ogr_Delta PF04606.7 GAP82432.1 - 7.3 6.3 6.5 12 5.6 1.4 3.0 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger FAA_hydrolase PF01557.13 GAP82433.1 - 2.3e-62 210.2 0.1 3.4e-62 209.7 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_6 PF12697.2 GAP82433.1 - 2.6e-21 76.5 8.6 2.6e-21 76.5 6.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP82433.1 - 4.3e-10 39.5 0.1 8.3e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP82433.1 - 6.8e-10 38.8 1.1 1.7e-09 37.5 0.4 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 GAP82433.1 - 3.5e-05 23.4 0.1 7.2e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_8 PF06259.7 GAP82433.1 - 0.014 14.9 0.9 0.38 10.2 0.1 2.5 2 0 0 2 2 2 0 Alpha/beta hydrolase Hydrolase_4 PF12146.3 GAP82433.1 - 0.081 12.7 0.1 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 Putative lysophospholipase DAO PF01266.19 GAP82434.1 - 1.3e-28 99.9 2.1 1.6e-28 99.6 1.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF1517 PF07466.6 GAP82434.1 - 1.6 7.6 3.4 2.8 6.8 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Abhydrolase_6 PF12697.2 GAP82435.1 - 2.4e-21 76.6 14.2 1.4e-20 74.1 8.4 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP82435.1 - 9.8e-05 22.1 0.1 0.00035 20.3 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP82435.1 - 0.00015 21.4 0.0 0.00019 21.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 GAP82435.1 - 0.00074 18.0 0.0 0.001 17.5 0.0 1.1 1 0 0 1 1 1 1 Ndr family Serglycin PF04360.7 GAP82436.1 - 0.027 14.1 1.1 0.055 13.1 0.8 1.4 1 0 0 1 1 1 0 Serglycin TauD PF02668.11 GAP82437.1 - 8.6e-29 100.9 0.0 1.1e-28 100.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Exonuc_VII_S PF02609.11 GAP82438.1 - 0.58 9.9 3.1 3.6 7.4 0.1 3.3 3 1 0 3 3 3 0 Exonuclease VII small subunit DUF4407 PF14362.1 GAP82438.1 - 2.4 7.0 14.2 17 4.2 9.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FAD_binding_3 PF01494.14 GAP82443.1 - 1e-07 31.3 0.5 5.3e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NMT1 PF09084.6 GAP82445.1 - 3.1e-10 40.0 0.0 4.7e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.15 GAP82445.1 - 0.012 14.8 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 NMT1_2 PF13379.1 GAP82445.1 - 0.065 12.6 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family Phosphonate-bd PF12974.2 GAP82445.1 - 0.079 12.3 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein zf-C2H2 PF00096.21 GAP82446.1 - 9.4e-10 38.2 8.5 5.1e-05 23.3 0.3 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP82446.1 - 2.3e-07 30.6 5.0 0.0068 16.6 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAP82446.1 - 0.031 14.5 16.3 0.035 14.4 2.2 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-met PF12874.2 GAP82446.1 - 0.2 11.8 1.2 18 5.7 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DSPc PF00782.15 GAP82447.1 - 4.6e-11 42.4 0.0 8.1e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAP82447.1 - 0.00028 20.2 0.0 0.00051 19.4 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 GAP82447.1 - 0.00056 20.2 0.1 0.0011 19.2 0.1 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 GAP82447.1 - 0.073 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.7 GAP82447.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) DSPn PF14671.1 GAP82447.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half Mito_carr PF00153.22 GAP82448.1 - 2.6e-28 97.5 0.4 8.5e-16 57.4 0.0 3.8 3 1 0 3 3 3 2 Mitochondrial carrier protein Med3 PF11593.3 GAP82448.1 - 0.61 9.2 9.7 0.042 13.0 2.9 1.7 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal TSA PF03249.8 GAP82448.1 - 0.65 8.4 7.9 1 7.7 5.5 1.2 1 0 0 1 1 1 0 Type specific antigen Zn_clus PF00172.13 GAP82449.1 - 0.00025 20.8 11.3 0.00053 19.8 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 GAP82450.1 - 1.1e-07 31.9 0.4 2.3e-07 30.9 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP82450.1 - 6.5e-06 25.9 0.1 1.4e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 KR domain Glyco_tran_WecB PF03808.8 GAP82450.1 - 0.0053 16.1 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase WecB/TagA/CpsF family T2SE_Nter PF05157.10 GAP82450.1 - 0.028 14.4 0.0 0.092 12.7 0.0 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein E, N-terminal domain Semialdhyde_dh PF01118.19 GAP82450.1 - 0.042 14.1 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Hexapep_2 PF14602.1 GAP82450.1 - 0.25 10.9 2.2 0.6 9.7 0.2 2.3 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase NmrA PF05368.8 GAP82453.1 - 0.00047 19.4 0.0 0.0007 18.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family DnaJ PF00226.26 GAP82454.1 - 9.5e-21 73.3 3.0 1.6e-20 72.5 0.7 2.4 2 0 0 2 2 2 1 DnaJ domain INCENP_ARK-bind PF03941.10 GAP82455.1 - 6.1e-17 61.1 0.5 6.1e-17 61.1 0.3 2.2 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region NOT2_3_5 PF04153.13 GAP82456.1 - 3.3e-30 104.6 4.0 6.3e-30 103.7 2.8 1.5 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family cobW PF02492.14 GAP82457.1 - 2.1e-45 154.3 0.3 2.9e-45 153.8 0.2 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 GAP82457.1 - 0.0021 17.6 0.4 0.015 14.8 0.3 2.1 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 GAP82457.1 - 0.0039 16.0 3.6 0.89 8.2 0.1 3.1 4 0 0 4 4 4 2 ArgK protein AAA_19 PF13245.1 GAP82457.1 - 0.004 16.8 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain CobW_C PF07683.9 GAP82457.1 - 0.01 15.5 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain Arch_ATPase PF01637.13 GAP82457.1 - 0.021 14.5 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_22 PF13401.1 GAP82457.1 - 0.022 14.9 0.2 0.21 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 GAP82457.1 - 0.022 15.0 0.1 0.038 14.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 GAP82457.1 - 0.03 14.2 0.6 0.091 12.7 0.4 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 GAP82457.1 - 0.048 13.9 0.3 0.12 12.7 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 GAP82457.1 - 0.069 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_30 PF13604.1 GAP82457.1 - 0.074 12.6 1.2 1.9 8.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 GAP82457.1 - 0.1 12.1 1.0 0.23 10.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.1 GAP82457.1 - 0.11 12.4 0.1 0.29 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 GAP82457.1 - 0.11 11.6 0.0 0.22 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 p450 PF00067.17 GAP82458.1 - 4.4e-57 193.6 0.0 5.3e-57 193.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sec34 PF04136.10 GAP82458.1 - 0.13 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Sec34-like family Mob1_phocein PF03637.12 GAP82459.1 - 9e-26 90.5 0.2 1.4e-25 89.9 0.2 1.2 1 0 0 1 1 1 1 Mob1/phocein family Fungal_trans_2 PF11951.3 GAP82460.1 - 8e-11 41.1 0.8 2.3e-10 39.6 0.5 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP82460.1 - 7e-07 29.0 10.6 1.4e-06 28.0 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MOSC PF03473.12 GAP82461.1 - 4.3e-16 58.5 0.0 8e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 GAP82461.1 - 2.5e-13 49.7 0.0 4.5e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain SMC_N PF02463.14 GAP82462.1 - 2.3e-65 219.8 18.6 2.1e-64 216.7 12.9 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 GAP82462.1 - 8.3e-23 80.6 0.2 3.9e-22 78.4 0.2 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 GAP82462.1 - 3.4e-12 46.9 4.3 3.6e-05 23.8 0.2 3.4 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 GAP82462.1 - 7.5e-10 39.4 21.7 7.5e-10 39.4 15.0 7.2 2 2 0 3 3 3 1 AAA domain Reo_sigmaC PF04582.7 GAP82462.1 - 4.7e-06 26.0 40.1 0.0024 17.1 1.6 7.4 3 2 4 8 8 8 4 Reovirus sigma C capsid protein AAA_29 PF13555.1 GAP82462.1 - 0.00084 18.8 0.0 0.002 17.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 GAP82462.1 - 0.064 13.5 0.0 0.064 13.5 0.0 6.1 3 2 1 5 5 5 0 ABC transporter Saccharop_dh PF03435.13 GAP82463.1 - 2.6e-12 46.4 0.1 3.1e-12 46.1 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase CUE PF02845.11 GAP82464.1 - 4.3e-08 32.4 0.0 6.7e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 CUE domain Glyco_transf_28 PF03033.15 GAP82464.1 - 0.038 13.7 0.0 0.31 10.7 0.0 2.0 1 1 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain DMA PF03474.9 GAP82464.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 DMRTA motif DEAD PF00270.24 GAP82466.1 - 1.1e-26 93.2 0.0 5.7e-26 91.0 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP82466.1 - 1.1e-20 73.2 0.1 2.6e-20 72.0 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 GAP82466.1 - 0.0073 16.2 0.0 0.038 13.9 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain DUF2824 PF11039.3 GAP82466.1 - 0.17 11.5 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2824) WD40 PF00400.27 GAP82467.1 - 1.7e-28 97.4 10.5 1.1e-07 31.4 0.2 6.5 7 0 0 7 7 7 6 WD domain, G-beta repeat 2OG-FeII_Oxy_2 PF13532.1 GAP82468.1 - 1.3e-33 116.4 0.1 1.7e-33 116.0 0.1 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CUE PF02845.11 GAP82468.1 - 5.5e-07 28.9 0.1 9.7e-07 28.1 0.0 1.4 1 0 0 1 1 1 1 CUE domain zf-GRF PF06839.7 GAP82468.1 - 0.028 14.3 0.2 0.073 13.0 0.0 1.8 2 0 0 2 2 2 0 GRF zinc finger 2OG-FeII_Oxy PF03171.15 GAP82468.1 - 0.052 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 GAP82469.1 - 8.6e-23 80.6 17.7 1e-22 80.3 12.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP82469.1 - 8.5e-06 24.5 3.9 1.1e-05 24.2 2.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter PUCC PF03209.10 GAP82469.1 - 0.074 11.7 5.4 0.098 11.3 3.7 1.1 1 0 0 1 1 1 0 PUCC protein GFA PF04828.9 GAP82470.1 - 2.3e-09 37.0 5.9 1.2e-05 25.0 0.2 2.9 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme Rsm1 PF08600.5 GAP82470.1 - 0.17 11.7 1.8 1.2 9.0 0.1 2.4 2 0 0 2 2 2 0 Rsm1-like DUF2116 PF09889.4 GAP82470.1 - 0.64 9.8 6.3 0.25 11.1 0.5 2.4 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Cys_rich_CWC PF14375.1 GAP82470.1 - 8.1 6.4 13.4 5.8 6.9 0.2 3.0 3 0 0 3 3 3 0 Cysteine-rich CWC AT_hook PF02178.14 GAP82473.1 - 0.11 12.2 20.1 0.21 11.3 3.8 3.2 2 0 0 2 2 2 0 AT hook motif Fungal_trans PF04082.13 GAP82475.1 - 1.2e-28 99.7 0.0 1.8e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP82475.1 - 2.4e-08 33.7 10.9 3.8e-08 33.1 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.10 GAP82476.1 - 9.3e-21 73.8 28.3 8.2e-20 70.7 19.6 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.11 GAP82477.1 - 1.7e-35 122.3 22.9 9.9e-32 110.0 0.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP82477.1 - 2e-09 36.5 2.4 2e-09 36.5 1.7 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 GAP82477.1 - 0.00019 19.9 1.7 0.00019 19.9 1.2 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.8 GAP82477.1 - 0.0054 14.9 0.7 0.009 14.2 0.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Coq4 PF05019.8 GAP82478.1 - 8.2e-77 257.0 0.0 9.5e-77 256.8 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 UQ_con PF00179.21 GAP82481.1 - 3.8e-10 39.3 0.0 6e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DNA_pol_viral_N PF00242.12 GAP82482.1 - 0.32 9.9 6.0 0.6 9.0 4.2 1.5 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Ras PF00071.17 GAP82483.1 - 2.1e-62 209.2 0.1 2.3e-62 209.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAP82483.1 - 3.5e-22 79.1 0.1 4.6e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAP82483.1 - 2.7e-13 49.5 0.0 3.2e-13 49.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAP82483.1 - 1.1e-08 35.0 0.1 1.5e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 GAP82483.1 - 1.6e-05 25.0 0.3 4.1e-05 23.7 0.0 1.8 2 1 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.7 GAP82483.1 - 3.9e-05 22.9 0.1 5.2e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAP82483.1 - 4e-05 23.1 0.1 0.00014 21.3 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 GAP82483.1 - 0.00087 19.1 0.1 0.0018 18.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 GAP82483.1 - 0.0019 17.3 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 GAP82483.1 - 0.0019 17.3 0.1 0.0036 16.5 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 GAP82483.1 - 0.008 15.7 0.2 0.032 13.7 0.1 1.8 1 1 1 2 2 2 1 AAA domain SRPRB PF09439.5 GAP82483.1 - 0.011 15.0 0.0 0.016 14.4 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 GAP82483.1 - 0.012 15.8 0.1 0.02 15.2 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 GAP82483.1 - 0.021 14.7 0.1 0.031 14.2 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain SpoIIID PF12116.3 GAP82483.1 - 0.023 14.5 0.1 0.37 10.7 0.0 2.1 2 0 0 2 2 2 0 Stage III sporulation protein D AAA_32 PF13654.1 GAP82483.1 - 0.049 12.2 0.1 0.54 8.8 0.0 2.0 1 1 1 2 2 2 0 AAA domain FeoB_N PF02421.13 GAP82483.1 - 0.06 12.6 0.1 0.14 11.3 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 GAP82483.1 - 0.068 12.7 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 GAP82483.1 - 0.096 12.4 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 GAP82483.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PfkB PF00294.19 GAP82484.1 - 1.8e-43 148.8 3.4 5.3e-43 147.2 2.3 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Inositol_P PF00459.20 GAP82485.1 - 7e-60 202.6 0.1 8.1e-60 202.4 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF1134 PF06577.7 GAP82485.1 - 0.095 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1134) eIF3g PF12353.3 GAP82490.1 - 6.4e-46 155.4 2.6 9.3e-46 154.9 1.8 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 GAP82490.1 - 7.9e-15 54.2 0.0 1.6e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP82490.1 - 2.6e-12 46.5 0.1 5.2e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP82490.1 - 2.7e-07 30.3 0.3 5.9e-07 29.2 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PEMT PF04191.8 GAP82491.1 - 8.8e-54 180.1 20.0 4.2e-34 116.8 1.6 2.9 3 0 0 3 3 3 2 Phospholipid methyltransferase CDC45 PF02724.9 GAP82492.1 - 2.3 6.1 4.3 5.1 4.9 3.0 1.5 1 1 0 1 1 1 0 CDC45-like protein HeLo PF14479.1 GAP82493.1 - 0.00049 19.9 0.6 0.0051 16.5 0.0 2.8 3 1 0 3 3 3 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.12 GAP82493.1 - 0.086 11.8 0.0 1.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase Ank_2 PF12796.2 GAP82494.1 - 1.5e-44 150.2 1.7 2.1e-15 56.8 0.1 6.2 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAP82494.1 - 3.4e-33 111.7 18.8 9.5e-06 25.1 0.3 9.7 9 1 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.1 GAP82494.1 - 9e-31 105.2 9.4 1.7e-08 34.4 0.2 8.7 6 1 2 8 8 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAP82494.1 - 1.3e-29 102.0 7.2 7.4e-07 29.5 0.1 7.9 2 1 6 8 8 8 8 Ankyrin repeats (many copies) Pkinase PF00069.20 GAP82494.1 - 2.5e-27 95.6 0.0 4e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_3 PF13606.1 GAP82494.1 - 3.9e-26 88.5 11.0 0.00091 19.2 0.0 9.4 9 0 0 9 9 9 7 Ankyrin repeat Pkinase_Tyr PF07714.12 GAP82494.1 - 5.9e-19 68.1 0.0 9.6e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.7 GAP82494.1 - 0.095 13.3 0.0 0.24 12.0 0.0 1.7 1 0 0 1 1 1 0 Sel1 repeat ADH_zinc_N PF00107.21 GAP82495.1 - 9.6e-09 34.8 0.0 2e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP82495.1 - 3.1e-05 23.7 0.0 6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PHO4 PF01384.15 GAP82495.1 - 0.022 13.4 0.0 0.034 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphate transporter family NAD_binding_8 PF13450.1 GAP82496.1 - 0.00087 19.2 0.1 0.0028 17.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 GAP82496.1 - 0.022 13.8 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain adh_short_C2 PF13561.1 GAP82497.1 - 2.9e-32 112.3 0.1 3.4e-32 112.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAP82497.1 - 1e-22 80.8 5.9 1.6e-22 80.1 4.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP82497.1 - 9.5e-10 38.4 5.9 9.9e-10 38.3 1.4 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 GAP82497.1 - 4.7e-06 26.2 0.6 0.001 18.5 0.2 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 GAP82497.1 - 0.22 10.6 2.3 0.69 9.0 0.2 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 GAP82497.1 - 0.29 11.1 8.3 8 6.4 0.0 2.6 2 1 0 2 2 2 0 NADH(P)-binding Pec_lyase_C PF00544.14 GAP82498.1 - 4.9e-21 75.1 6.5 7.4e-21 74.5 4.5 1.2 1 0 0 1 1 1 1 Pectate lyase AP_endonuc_2 PF01261.19 GAP82499.1 - 7.8e-25 87.4 0.3 1.1e-24 86.9 0.2 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Sugar_tr PF00083.19 GAP82500.1 - 3.9e-105 352.0 21.3 4.7e-105 351.7 14.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP82500.1 - 2.4e-22 79.1 50.8 2e-21 76.1 16.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox_2 PF07992.9 GAP82501.1 - 1.1e-12 48.2 0.0 6.3e-10 39.2 0.0 3.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAP82501.1 - 1.8e-12 47.5 0.0 3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP82501.1 - 1e-09 38.7 0.1 2e-05 24.7 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAP82501.1 - 1.6e-09 37.1 0.4 0.00045 19.2 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 GAP82501.1 - 6.4e-08 31.8 0.0 2.7e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 GAP82501.1 - 0.0001 21.3 0.2 0.034 13.0 0.0 2.4 2 1 1 3 3 3 2 Lycopene cyclase protein Trp_halogenase PF04820.9 GAP82501.1 - 0.0022 16.7 0.1 0.82 8.2 0.0 2.1 1 1 1 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.9 GAP82501.1 - 0.004 15.6 0.0 1.4 7.2 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.1 GAP82501.1 - 0.016 14.9 1.9 1.9 8.2 0.0 3.1 2 1 1 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 GAP82501.1 - 0.032 14.4 0.1 0.096 12.9 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding adh_short PF00106.20 GAP82502.1 - 2.7e-29 102.2 2.3 3.7e-29 101.7 1.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP82502.1 - 2.6e-28 99.4 0.0 3.1e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP82502.1 - 1.2e-14 54.4 1.0 1.6e-14 54.0 0.7 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 GAP82502.1 - 0.0001 22.0 0.1 0.00016 21.3 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 GAP82502.1 - 0.00035 20.0 0.1 0.00079 18.9 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_18 PF12847.2 GAP82502.1 - 0.00078 20.0 0.0 0.0014 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Pyr_redox PF00070.22 GAP82502.1 - 0.0015 18.9 0.2 0.0091 16.3 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_31 PF13847.1 GAP82502.1 - 0.007 15.9 0.0 0.23 11.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 GAP82502.1 - 0.01 14.7 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_26 PF13659.1 GAP82502.1 - 0.026 14.5 0.0 0.054 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 GAP82502.1 - 0.027 13.8 0.1 0.047 13.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain TrkA_N PF02254.13 GAP82502.1 - 0.037 14.0 0.0 0.079 12.9 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 GAP82502.1 - 0.04 13.0 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 GAP82502.1 - 0.32 10.9 2.4 1.3 8.9 1.7 2.0 1 1 0 1 1 1 0 NADH(P)-binding AP_endonuc_2 PF01261.19 GAP82503.1 - 1.4e-22 80.0 0.0 2e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF4511 PF14974.1 GAP82504.1 - 0.0016 18.1 0.3 0.0027 17.4 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4511) Phytoreo_S7 PF07236.6 GAP82504.1 - 0.033 12.5 0.3 0.05 11.9 0.2 1.3 1 1 0 1 1 1 0 Phytoreovirus S7 protein DUF2397 PF09660.5 GAP82504.1 - 0.078 11.5 0.0 0.18 10.3 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2397) Peptidase_C97 PF05903.9 GAP82507.1 - 1.5e-06 28.0 0.0 2.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 GAP82507.1 - 0.13 12.1 0.3 0.37 10.7 0.0 1.9 2 0 0 2 2 2 0 Lecithin retinol acyltransferase DnaJ PF00226.26 GAP82508.1 - 2.8e-10 39.7 1.2 4.9e-10 39.0 0.3 1.8 2 0 0 2 2 2 1 DnaJ domain AATF-Che1 PF13339.1 GAP82508.1 - 0.014 15.5 0.5 0.014 15.5 0.3 1.8 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF3678 PF12435.3 GAP82508.1 - 0.84 9.2 9.0 1.7 8.2 6.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) Nucleos_tra2_C PF07662.8 GAP82509.1 - 6.6e-70 234.8 4.2 6.6e-70 234.8 2.9 2.2 2 1 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 GAP82509.1 - 5.9e-21 74.6 2.5 5.9e-21 74.6 1.8 3.6 5 0 0 5 5 5 1 Na+ dependent nucleoside transporter N-terminus Terpene_synth_C PF03936.11 GAP82510.1 - 1.4e-09 37.5 0.0 2e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.17 GAP82511.1 - 2.7e-07 29.4 0.0 1e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 GAP82512.1 - 6.5e-08 32.1 0.2 0.002 17.5 0.1 2.5 1 1 1 2 2 2 2 FAD binding domain BBE PF08031.7 GAP82512.1 - 8.3e-08 32.0 0.1 2.4e-07 30.5 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like Brix PF04427.13 GAP82513.1 - 2.1e-56 190.6 0.0 2.7e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 Brix domain TFIIA PF03153.8 GAP82513.1 - 0.68 9.7 14.7 1.1 9.1 10.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3840 PF12944.2 GAP82513.1 - 2.1 8.2 0.0 2.1 8.2 0.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3840) DUF2962 PF11176.3 GAP82514.1 - 0.07 12.7 0.2 0.083 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2962) FAM180 PF15173.1 GAP82514.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 FAM180 family MAD PF05557.8 GAP82515.1 - 0.039 12.0 6.3 0.085 10.9 1.0 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein TIP120 PF08623.5 GAP82515.1 - 0.4 10.2 2.6 0.26 10.8 0.1 1.7 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) Tropomyosin PF00261.15 GAP82515.1 - 0.52 9.3 13.0 1.6 7.7 2.7 2.2 2 0 0 2 2 2 0 Tropomyosin DUF4140 PF13600.1 GAP82515.1 - 1.7 9.1 5.8 3.7 8.0 0.5 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) ATP-synt_B PF00430.13 GAP82515.1 - 4.8 6.9 9.3 0.3 10.9 2.3 1.8 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) adh_short PF00106.20 GAP82516.1 - 1.9e-05 24.6 1.9 4.1e-05 23.5 1.3 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Ribosomal_60s PF00428.14 GAP82516.1 - 0.16 12.3 4.2 0.32 11.4 2.9 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF676 PF05057.9 GAP82517.1 - 2.3e-08 33.6 0.0 4.2e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_22 PF13401.1 GAP82517.1 - 6e-08 32.9 0.0 1.1e-05 25.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 GAP82517.1 - 7.4e-08 32.2 0.0 8.6e-06 25.5 0.0 2.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 GAP82517.1 - 3e-06 27.3 0.0 1.6e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain Abhydrolase_6 PF12697.2 GAP82517.1 - 7.2e-06 26.0 0.3 5.5e-05 23.1 0.0 2.5 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP82517.1 - 2.1e-05 24.2 0.0 4.3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family RNA_helicase PF00910.17 GAP82517.1 - 0.00034 20.7 0.0 0.001 19.1 0.0 1.8 2 0 0 2 2 1 1 RNA helicase AAA PF00004.24 GAP82517.1 - 0.0014 18.8 0.0 0.062 13.5 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PGAP1 PF07819.8 GAP82517.1 - 0.0065 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein AAA_10 PF12846.2 GAP82517.1 - 0.023 14.1 0.0 0.068 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 GAP82517.1 - 0.026 15.3 0.0 0.41 11.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain Torsin PF06309.6 GAP82517.1 - 0.032 14.1 0.0 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 Torsin Lipase_3 PF01764.20 GAP82517.1 - 0.044 13.3 0.0 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 3) AAA_5 PF07728.9 GAP82517.1 - 0.094 12.4 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 GAP82517.1 - 0.1 12.2 0.0 0.84 9.2 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 GAP82517.1 - 0.11 12.5 0.0 2.9 7.9 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.1 GAP82517.1 - 0.16 11.7 0.0 0.63 9.8 0.0 2.0 2 0 0 2 2 1 0 Part of AAA domain ArgK PF03308.11 GAP82517.1 - 0.2 10.4 0.0 0.38 9.4 0.0 1.4 1 0 0 1 1 1 0 ArgK protein NTPase_1 PF03266.10 GAP82517.1 - 0.2 11.3 0.0 0.67 9.6 0.0 1.9 1 0 0 1 1 1 0 NTPase APS_kinase PF01583.15 GAP82517.1 - 0.2 11.2 0.0 0.4 10.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Cutinase PF01083.17 GAP82518.1 - 2.1e-05 24.3 0.0 3.3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Cutinase DUF676 PF05057.9 GAP82518.1 - 0.00062 19.1 0.0 0.0024 17.2 0.0 1.9 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 GAP82518.1 - 0.0071 16.1 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP82518.1 - 0.0075 16.1 0.1 0.015 15.1 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP82518.1 - 0.067 12.7 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.9 GAP82519.1 - 2.9e-06 26.7 0.0 4.3e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 GAP82519.1 - 9.6e-05 22.1 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAP82519.1 - 0.00021 20.9 0.0 0.00035 20.2 0.0 1.5 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 GAP82519.1 - 0.00034 20.5 0.0 0.00041 20.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 GAP82519.1 - 0.00045 20.0 0.0 0.00064 19.4 0.0 1.2 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.20 GAP82519.1 - 0.0022 17.6 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Excalibur PF05901.6 GAP82520.1 - 0.087 13.1 0.7 0.48 10.7 0.0 2.4 3 0 0 3 3 3 0 Excalibur calcium-binding domain Amidohydro_5 PF13594.1 GAP82521.1 - 7.4e-05 22.4 0.0 0.00028 20.6 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 GAP82521.1 - 0.00084 19.0 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family RabGAP-TBC PF00566.13 GAP82523.1 - 7.3e-36 123.6 0.0 3.1e-32 111.8 0.0 2.8 2 1 0 2 2 2 2 Rab-GTPase-TBC domain UQ_con PF00179.21 GAP82524.1 - 7.4e-41 138.8 0.0 8.1e-41 138.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAP82524.1 - 1.6e-07 31.1 0.0 1.9e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 GAP82524.1 - 0.0014 18.5 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain WH2 PF02205.15 GAP82527.1 - 3.9e-09 35.8 0.4 3.9e-09 35.8 0.3 2.5 3 0 0 3 3 3 1 WH2 motif Fibrinogen_aC PF12160.3 GAP82528.1 - 0.098 12.1 1.1 0.27 10.7 0.8 1.7 1 1 0 1 1 1 0 Fibrinogen alpha C domain F-box PF00646.28 GAP82529.1 - 0.02 14.5 0.1 0.098 12.3 0.0 2.2 3 0 0 3 3 3 0 F-box domain COesterase PF00135.23 GAP82530.1 - 4.1e-05 22.4 0.0 4.7e-05 22.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Glutaredoxin PF00462.19 GAP82531.1 - 7.7e-13 48.2 0.0 2e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 GAP82531.1 - 0.012 15.8 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain COesterase PF00135.23 GAP82532.1 - 6.4e-93 312.2 0.0 8.2e-93 311.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAP82532.1 - 0.00024 20.7 3.6 0.00028 20.5 0.2 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAP82532.1 - 0.015 14.4 0.8 0.029 13.5 0.5 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family tRNA-synt_2b PF00587.20 GAP82533.1 - 4.2e-35 120.8 0.0 6.1e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAP82533.1 - 5e-07 29.5 0.0 2.5e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain CBF PF03914.12 GAP82534.1 - 1.7e-44 151.1 0.3 1.7e-44 151.1 0.2 2.8 3 0 0 3 3 3 1 CBF/Mak21 family 4HBT PF03061.17 GAP82537.1 - 3.6e-11 43.0 0.9 5.8e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 Thioesterase superfamily APS_kinase PF01583.15 GAP82538.1 - 1.2e-69 232.9 0.0 1.4e-69 232.6 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 GAP82538.1 - 1.3e-07 31.5 0.0 1.9e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAP82538.1 - 1.3e-05 26.0 0.1 2.2e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 GAP82538.1 - 0.00041 19.6 0.0 0.00055 19.2 0.0 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 GAP82538.1 - 0.00064 20.0 0.2 0.0011 19.3 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 GAP82538.1 - 0.043 13.3 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain V-ATPase_C PF03223.10 GAP82540.1 - 1.9e-113 379.1 0.1 2.3e-113 378.8 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Cupin_2 PF07883.6 GAP82541.1 - 1.6e-10 40.3 0.0 2.5e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain CDO_I PF05995.7 GAP82541.1 - 0.0062 15.7 0.0 0.0092 15.1 0.0 1.3 1 1 0 1 1 1 1 Cysteine dioxygenase type I DUF4437 PF14499.1 GAP82541.1 - 0.084 11.7 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) Pirin PF02678.11 GAP82541.1 - 0.09 12.6 0.1 0.14 12.0 0.0 1.4 1 1 0 1 1 1 0 Pirin AT_hook PF02178.14 GAP82542.1 - 5.4 7.0 19.6 9.3 6.3 4.2 3.2 2 0 0 2 2 2 0 AT hook motif F-box PF00646.28 GAP82543.1 - 5.5e-07 29.0 0.3 1.5e-06 27.6 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAP82543.1 - 0.00012 21.6 1.3 0.0003 20.4 0.0 2.4 3 0 0 3 3 3 1 F-box-like FBPase PF00316.15 GAP82544.1 - 8.3e-34 116.8 0.0 1.2e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase TRM PF02005.11 GAP82547.1 - 5.9e-107 357.8 0.0 9.2e-94 314.4 0.0 2.4 2 1 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 GAP82547.1 - 0.00027 20.9 0.3 0.00087 19.3 0.2 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP82547.1 - 0.0015 18.1 0.0 0.0032 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 GAP82547.1 - 0.0016 18.0 0.0 0.0036 16.9 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_3 PF01596.12 GAP82547.1 - 0.015 14.3 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase MTS PF05175.9 GAP82547.1 - 0.028 13.7 0.0 0.19 11.0 0.0 2.2 3 0 0 3 3 3 0 Methyltransferase small domain Methyltransf_15 PF09445.5 GAP82547.1 - 0.037 13.5 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 GAP82547.1 - 0.046 14.2 0.0 0.099 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF2067 PF09840.4 GAP82547.1 - 0.068 12.6 0.0 0.37 10.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2067) F-box PF00646.28 GAP82549.1 - 0.0051 16.4 0.0 0.013 15.1 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAP82549.1 - 0.035 13.8 0.1 0.096 12.4 0.1 1.7 1 0 0 1 1 1 0 F-box-like APH PF01636.18 GAP82550.1 - 1e-06 28.6 0.0 1.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 GAP82550.1 - 0.00012 21.3 0.0 0.00021 20.5 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 GAP82550.1 - 0.014 14.0 0.0 0.02 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.9 GAP82550.1 - 0.17 10.8 0.0 0.52 9.2 0.0 1.7 2 0 0 2 2 2 0 Fructosamine kinase SprT-like PF10263.4 GAP82551.1 - 0.098 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 SprT-like family DUF1996 PF09362.5 GAP82552.1 - 1.9e-36 125.9 0.1 2.3e-36 125.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) FKBP_C PF00254.23 GAP82553.1 - 3e-26 91.2 0.1 3.7e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase MFS_1 PF07690.11 GAP82555.1 - 2.4e-26 92.3 29.2 2.4e-26 92.2 19.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3112 PF11309.3 GAP82556.1 - 4.1e-41 140.4 7.3 6.9e-38 129.9 0.4 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) adh_short PF00106.20 GAP82557.1 - 0.022 14.7 0.0 0.041 13.7 0.0 1.4 1 1 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 GAP82557.1 - 0.035 13.7 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 KR domain Metallophos PF00149.23 GAP82558.1 - 3.4e-44 150.6 0.9 4.3e-44 150.3 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Vps51 PF08700.6 GAP82559.1 - 1.9e-16 59.6 2.1 1.9e-16 59.6 1.4 2.0 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 GAP82559.1 - 0.00075 19.3 5.1 0.0057 16.5 0.4 2.8 2 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec5 PF15469.1 GAP82559.1 - 0.0024 17.6 4.0 0.89 9.2 0.7 2.6 2 0 0 2 2 2 2 Exocyst complex component Sec5 XPG_I_2 PF12813.2 GAP82559.1 - 0.064 12.7 1.1 0.18 11.2 0.4 1.9 2 0 0 2 2 2 0 XPG domain containing DUF677 PF05055.7 GAP82559.1 - 0.12 11.0 3.2 0.076 11.6 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF677) APG6 PF04111.7 GAP82559.1 - 2.5 7.0 11.8 0.071 12.1 1.8 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 Atg14 PF10186.4 GAP82559.1 - 4.1 6.2 10.3 0.4 9.5 0.9 2.3 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 GAP82559.1 - 8.4 4.1 9.8 0.11 10.3 0.7 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family IncA PF04156.9 GAP82559.1 - 9.9 5.7 9.3 4 6.9 1.3 2.3 2 0 0 2 2 2 0 IncA protein MAS20 PF02064.10 GAP82560.1 - 3.4e-18 65.7 0.9 1.4e-17 63.7 0.6 1.7 1 1 0 1 1 1 1 MAS20 protein import receptor Transglut_prok PF09017.5 GAP82560.1 - 0.024 13.7 0.4 0.028 13.5 0.3 1.1 1 0 0 1 1 1 0 Microbial transglutaminase NAM-associated PF14303.1 GAP82560.1 - 0.027 14.7 0.2 0.035 14.4 0.1 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Nop25 PF09805.4 GAP82560.1 - 0.16 12.0 5.3 0.21 11.6 3.6 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Radical_SAM PF04055.16 GAP82561.1 - 2.8e-25 89.4 0.1 7.6e-25 88.0 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Wyosine_form PF08608.7 GAP82561.1 - 1.7e-22 79.2 0.0 4e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 GAP82561.1 - 1.5e-09 37.9 0.3 1.2e-07 31.8 0.2 2.9 1 1 0 1 1 1 1 Flavodoxin Aminotran_1_2 PF00155.16 GAP82563.1 - 7.3e-53 179.7 0.1 8.1e-53 179.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Oxidored_FMN PF00724.15 GAP82563.1 - 0.013 14.4 0.0 0.017 14.1 0.0 1.1 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family SAP PF02037.22 GAP82564.1 - 1.3e-14 53.2 0.6 2.3e-14 52.4 0.4 1.4 1 0 0 1 1 1 1 SAP domain TFIIF_alpha PF05793.7 GAP82564.1 - 0.57 8.4 12.7 0.88 7.8 8.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GATase PF00117.23 GAP82565.1 - 7.3e-47 159.3 0.0 1e-46 158.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 GAP82565.1 - 1.4e-46 157.2 0.0 2.8e-46 156.2 0.0 1.5 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.8 GAP82565.1 - 2.3e-06 27.2 0.3 0.00036 20.0 0.2 2.7 1 1 0 1 1 1 1 Peptidase C26 ETF PF01012.16 GAP82566.1 - 2.9e-35 121.4 1.2 3.7e-35 121.0 0.8 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ArfGap PF01412.13 GAP82568.1 - 2.9e-32 110.8 0.1 5.4e-32 110.0 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RRM_1 PF00076.17 GAP82569.1 - 7.5e-31 105.5 0.1 1.6e-14 53.2 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP82569.1 - 3.3e-23 81.4 0.0 1.5e-11 44.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP82569.1 - 3.6e-08 33.1 0.0 0.0049 16.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 GAP82569.1 - 0.062 12.9 0.2 26 4.5 0.0 3.0 3 0 0 3 3 3 0 DbpA RNA binding domain API5 PF05918.6 GAP82569.1 - 0.2 10.1 2.6 0.29 9.5 1.8 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Flavodoxin_1 PF00258.20 GAP82570.1 - 9.4e-28 97.0 0.0 1.8e-27 96.1 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 GAP82570.1 - 1.9e-24 86.3 0.0 1.6e-22 80.0 0.0 2.3 1 1 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 GAP82570.1 - 4.6e-11 43.2 0.0 1e-10 42.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.2 GAP82570.1 - 0.015 14.7 0.0 0.052 12.9 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin domain Flavodoxin_5 PF12724.2 GAP82570.1 - 0.025 14.6 0.0 0.073 13.0 0.0 1.8 1 0 0 1 1 1 0 Flavodoxin domain FF PF01846.14 GAP82570.1 - 0.043 13.7 0.1 5 7.1 0.0 2.7 2 0 0 2 2 2 0 FF domain Abhydrolase_6 PF12697.2 GAP82572.1 - 0.00016 21.6 1.7 0.00016 21.6 1.2 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family LIP PF03583.9 GAP82572.1 - 0.00067 18.9 0.0 0.03 13.5 0.0 2.2 1 1 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 GAP82572.1 - 0.03 14.0 0.2 0.047 13.4 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 GAP82572.1 - 0.13 12.1 0.1 0.33 10.8 0.0 1.6 1 1 0 1 1 1 0 TAP-like protein Asp PF00026.18 GAP82573.1 - 1.5e-09 37.5 0.1 2.4e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DUF2613 PF11021.3 GAP82573.1 - 0.028 14.1 0.0 0.075 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) SKG6 PF08693.5 GAP82573.1 - 5.7 6.3 6.0 11 5.4 4.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain F-box-like PF12937.2 GAP82574.1 - 1.3e-07 31.1 0.1 2.4e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAP82574.1 - 4.4e-06 26.2 0.0 1.1e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain COPI_assoc PF08507.5 GAP82575.1 - 7.3e-45 152.0 5.4 8.9e-45 151.7 3.8 1.1 1 0 0 1 1 1 1 COPI associated protein DUF3784 PF12650.2 GAP82575.1 - 0.0044 16.9 8.4 0.0045 16.9 0.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3784) Cg6151-P PF10233.4 GAP82575.1 - 0.17 11.8 8.5 0.27 11.2 5.9 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein CG6151-P CRPA PF05745.6 GAP82575.1 - 0.25 11.1 2.3 0.43 10.3 1.6 1.3 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Ycf66_N PF07444.6 GAP82575.1 - 0.67 9.7 4.3 0.4 10.4 1.1 1.9 1 1 1 2 2 2 0 Ycf66 protein N-terminus DoxX PF07681.7 GAP82575.1 - 0.93 9.9 4.5 2.2 8.7 3.1 1.5 1 1 0 1 1 1 0 DoxX DUF308 PF03729.8 GAP82575.1 - 3.4 7.7 16.4 0.39 10.7 0.9 2.6 1 1 2 3 3 3 0 Short repeat of unknown function (DUF308) GATA PF00320.22 GAP82577.1 - 2.6e-31 106.6 16.7 7.3e-17 60.4 2.1 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 GAP82577.1 - 3e-06 26.4 2.3 0.012 14.8 0.1 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding zf-ribbon_3 PF13248.1 GAP82577.1 - 0.0006 18.9 5.6 0.37 10.0 0.2 3.0 2 1 0 2 2 2 2 zinc-ribbon domain ArfGap PF01412.13 GAP82577.1 - 0.0007 19.3 1.7 0.26 11.0 0.1 2.4 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf RRN7 PF11781.3 GAP82577.1 - 0.00071 19.0 7.6 0.018 14.5 0.3 2.5 2 0 0 2 2 2 2 RNA polymerase I-specific transcription initiation factor Rrn7 Zn-ribbon_8 PF09723.5 GAP82577.1 - 0.0023 17.8 1.5 0.81 9.6 0.1 2.8 2 0 0 2 2 2 2 Zinc ribbon domain OrfB_Zn_ribbon PF07282.6 GAP82577.1 - 0.0097 15.5 4.9 0.28 10.8 0.5 2.7 2 0 0 2 2 2 1 Putative transposase DNA-binding domain zf-Sec23_Sec24 PF04810.10 GAP82577.1 - 0.043 13.3 0.5 0.043 13.3 0.3 3.1 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger DZR PF12773.2 GAP82577.1 - 0.16 11.8 18.4 2.3 8.1 1.6 3.6 1 1 2 3 3 3 0 Double zinc ribbon Auto_anti-p27 PF06677.7 GAP82577.1 - 0.25 11.1 3.7 7.8 6.3 0.2 2.6 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-C2H2_3 PF13878.1 GAP82577.1 - 0.36 10.4 9.6 7.1 6.2 0.3 4.3 3 1 1 4 4 4 0 zinc-finger of acetyl-transferase ESCO Zn_Tnp_IS1595 PF12760.2 GAP82577.1 - 0.87 9.4 6.8 1.9 8.3 0.8 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain eIF-5_eIF-2B PF01873.12 GAP82577.1 - 1.4 8.5 5.7 5.8 6.6 0.4 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 A2L_zn_ribbon PF08792.5 GAP82577.1 - 3.6 7.1 7.4 11 5.5 0.1 3.9 4 0 0 4 4 4 0 A2L zinc ribbon domain Prim_Zn_Ribbon PF08273.7 GAP82577.1 - 3.8 7.6 16.6 3.9 7.6 2.0 3.9 2 2 1 3 3 3 0 Zinc-binding domain of primase-helicase Acetyltransf_1 PF00583.19 GAP82578.1 - 5e-05 23.2 0.1 7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAP82578.1 - 0.0033 17.5 0.0 0.0039 17.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAP82578.1 - 0.0079 16.3 0.1 0.0086 16.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAP82578.1 - 0.096 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein DHC_N1 PF08385.7 GAP82579.1 - 1.5e-187 624.5 15.3 1.5e-187 624.5 10.6 4.7 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 GAP82579.1 - 3.2e-126 421.1 8.0 3.2e-126 421.1 5.6 5.5 5 1 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 GAP82579.1 - 2.7e-101 339.7 0.0 1.6e-100 337.2 0.0 2.4 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 GAP82579.1 - 2.8e-76 256.0 0.0 7.8e-76 254.6 0.0 1.8 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 GAP82579.1 - 1.5e-41 142.1 0.2 2.2e-40 138.3 0.1 2.4 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 GAP82579.1 - 1.8e-41 141.4 0.1 1e-40 138.9 0.0 2.4 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 MT PF12777.2 GAP82579.1 - 4.3e-40 137.5 9.0 4.3e-40 137.5 6.2 2.2 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 GAP82579.1 - 8.7e-31 106.5 0.1 1.4e-11 44.2 0.0 6.4 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 GAP82579.1 - 2.9e-21 75.7 0.0 2.1e-19 69.6 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 GAP82579.1 - 9.4e-15 54.9 0.0 0.011 15.8 0.0 6.0 5 0 0 5 5 4 3 AAA domain AAA PF00004.24 GAP82579.1 - 1.8e-13 50.8 0.0 0.0015 18.7 0.0 5.0 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 GAP82579.1 - 4.6e-10 39.5 0.1 0.35 10.7 0.0 5.4 4 0 0 4 4 4 3 AAA domain AAA_17 PF13207.1 GAP82579.1 - 2.4e-09 38.0 1.5 0.031 15.0 0.0 6.3 6 0 0 6 6 4 2 AAA domain AAA_18 PF13238.1 GAP82579.1 - 1.7e-08 34.8 1.1 0.023 15.0 0.0 5.3 5 0 0 5 5 4 2 AAA domain AAA_16 PF13191.1 GAP82579.1 - 2.7e-08 34.0 10.5 0.12 12.3 0.0 7.7 6 1 1 7 7 6 2 AAA ATPase domain T2SE PF00437.15 GAP82579.1 - 1.8e-06 27.0 0.0 0.039 12.8 0.0 3.8 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_19 PF13245.1 GAP82579.1 - 2.3e-06 27.2 0.0 0.89 9.3 0.0 4.8 4 0 0 4 4 4 1 Part of AAA domain AAA_14 PF13173.1 GAP82579.1 - 5.7e-06 26.2 0.0 0.21 11.4 0.0 5.1 5 0 0 5 5 4 1 AAA domain AAA_29 PF13555.1 GAP82579.1 - 2.8e-05 23.5 0.0 2 7.9 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain Mg_chelatase PF01078.16 GAP82579.1 - 5.5e-05 22.4 1.0 0.5 9.4 0.0 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 GAP82579.1 - 0.00016 22.0 0.1 3.5 7.9 0.0 4.7 3 0 0 3 3 3 1 ABC transporter IstB_IS21 PF01695.12 GAP82579.1 - 0.00078 18.9 0.8 0.35 10.2 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_25 PF13481.1 GAP82579.1 - 0.004 16.5 0.5 0.39 10.0 0.0 3.5 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.17 GAP82579.1 - 0.0095 16.1 0.2 23 5.2 0.0 4.6 4 0 0 4 4 4 0 RNA helicase MobB PF03205.9 GAP82579.1 - 0.081 12.6 0.3 12 5.5 0.0 3.4 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B ERM PF00769.14 GAP82579.1 - 6.4 6.2 34.3 0.055 12.9 8.1 3.4 4 0 0 4 4 3 0 Ezrin/radixin/moesin family FAR1 PF03101.10 GAP82580.1 - 5.4e-07 30.0 0.0 1.7e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 FAR1 DNA-binding domain COG2 PF06148.6 GAP82580.1 - 0.2 11.5 2.0 0.67 9.8 1.2 2.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Mnd1 PF03962.10 GAP82580.1 - 3 7.4 8.6 0.071 12.7 0.5 2.2 2 1 0 2 2 2 0 Mnd1 family PEP-utilisers_N PF05524.8 GAP82580.1 - 4.4 7.1 9.2 0.21 11.3 0.5 2.7 2 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal DUF4200 PF13863.1 GAP82580.1 - 7.1 6.5 17.6 0.11 12.4 7.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Uso1_p115_C PF04871.8 GAP82580.1 - 8.6 6.2 11.2 0.96 9.3 2.5 2.4 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region zf-C2H2_4 PF13894.1 GAP82582.1 - 0.00081 19.5 13.2 0.029 14.6 0.1 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger Amidohydro_3 PF07969.6 GAP82583.1 - 2.9e-17 62.9 5.2 3.3e-17 62.8 3.6 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 GAP82583.1 - 0.0032 17.1 0.0 0.0043 16.7 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Acetyltransf_1 PF00583.19 GAP82584.1 - 0.00077 19.4 0.5 0.0013 18.6 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAP82584.1 - 0.055 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RseC_MucC PF04246.7 GAP82584.1 - 0.13 11.8 0.8 0.21 11.1 0.6 1.3 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Histone PF00125.19 GAP82585.1 - 4.3e-09 36.3 0.4 5.3e-09 36.0 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 GAP82585.1 - 0.027 14.3 0.1 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) HTH_17 PF12728.2 GAP82585.1 - 0.15 12.3 0.3 0.15 12.3 0.2 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Svf1 PF08622.5 GAP82586.1 - 1.5e-122 408.6 0.0 1.8e-122 408.3 0.0 1.1 1 0 0 1 1 1 1 Svf1-like KH_4 PF13083.1 GAP82586.1 - 0.013 15.0 0.0 0.034 13.8 0.0 1.6 1 0 0 1 1 1 0 KH domain Ribosomal_L11_N PF03946.9 GAP82587.1 - 2.6e-25 87.6 0.1 4.3e-25 86.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 GAP82587.1 - 2.1e-23 82.2 0.3 4.8e-23 81.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Pkinase PF00069.20 GAP82589.1 - 1.5e-59 201.2 0.0 2.3e-59 200.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP82589.1 - 7e-21 74.4 0.0 1.3e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAP82589.1 - 0.0045 16.7 0.4 0.011 15.4 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Cpn10 PF00166.16 GAP82590.1 - 1e-27 95.8 0.0 1.2e-27 95.7 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Glyco_hydro_61 PF03443.9 GAP82591.1 - 1.4e-44 152.5 0.0 1.9e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Cys_Met_Meta_PP PF01053.15 GAP82593.1 - 1.4e-137 458.1 0.1 1.5e-137 457.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 GAP82593.1 - 4.1e-09 35.8 0.1 6.2e-09 35.2 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 GAP82593.1 - 1.7e-06 27.3 0.6 3.1e-06 26.4 0.4 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 GAP82593.1 - 7.3e-06 24.9 0.7 1.3e-05 24.1 0.2 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 GAP82593.1 - 0.0015 17.6 0.4 0.0032 16.6 0.3 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase 2-Hacid_dh PF00389.25 GAP82593.1 - 0.053 12.9 0.1 0.062 12.7 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ABC_tran PF00005.22 GAP82594.1 - 7.7e-50 168.7 0.1 1.1e-27 96.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAP82594.1 - 6.7e-36 124.1 16.3 2e-18 66.8 1.4 2.7 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 GAP82594.1 - 1.2e-10 41.8 0.4 0.048 13.6 0.1 4.3 2 2 1 3 3 3 2 AAA domain SMC_N PF02463.14 GAP82594.1 - 5.1e-10 38.9 1.8 0.016 14.4 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 GAP82594.1 - 7.3e-08 32.9 1.8 3.6e-05 24.1 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 GAP82594.1 - 1.5e-07 31.0 0.0 0.008 15.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAP82594.1 - 2.3e-07 30.2 2.8 0.0093 15.4 0.3 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.18 GAP82594.1 - 1.4e-05 24.9 1.0 0.13 12.1 0.0 2.4 2 0 0 2 2 2 2 Dynamin family DUF258 PF03193.11 GAP82594.1 - 2.1e-05 23.7 0.2 0.11 11.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 GAP82594.1 - 2.4e-05 23.9 0.1 0.066 12.6 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain FtsK_SpoIIIE PF01580.13 GAP82594.1 - 5.9e-05 22.6 0.2 0.16 11.4 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family MobB PF03205.9 GAP82594.1 - 6.8e-05 22.5 0.6 0.042 13.5 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 GAP82594.1 - 0.00016 21.8 0.1 2 8.5 0.0 3.5 4 0 0 4 4 3 2 AAA domain Miro PF08477.8 GAP82594.1 - 0.00021 21.7 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein T2SE PF00437.15 GAP82594.1 - 0.00032 19.7 0.1 0.19 10.5 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.18 GAP82594.1 - 0.00032 20.6 0.2 0.061 13.2 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 GAP82594.1 - 0.00064 19.7 0.1 1 9.3 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.13 GAP82594.1 - 0.00074 19.1 0.0 1 8.8 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF87 PF01935.12 GAP82594.1 - 0.00099 18.9 4.4 0.011 15.5 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_19 PF13245.1 GAP82594.1 - 0.0011 18.6 0.1 0.3 10.8 0.0 3.2 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 GAP82594.1 - 0.0012 19.6 2.8 0.57 11.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 GAP82594.1 - 0.0014 18.4 0.2 2.2 8.2 0.1 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 GAP82594.1 - 0.0023 17.8 0.0 2.1 8.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 GAP82594.1 - 0.0039 16.9 0.0 0.22 11.1 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA_18 PF13238.1 GAP82594.1 - 0.0057 16.9 0.1 3.8 7.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 GAP82594.1 - 0.0078 15.8 1.7 1.9 8.1 0.2 2.6 2 0 0 2 2 2 1 NACHT domain ArgK PF03308.11 GAP82594.1 - 0.015 14.1 0.5 2 7.1 0.0 2.3 2 0 0 2 2 2 0 ArgK protein cobW PF02492.14 GAP82594.1 - 0.032 13.6 3.6 3.4 7.0 0.6 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 GAP82594.1 - 0.038 13.5 0.1 8.3 5.8 0.1 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_15 PF13175.1 GAP82594.1 - 0.041 12.9 0.1 1.8 7.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.10 GAP82594.1 - 0.06 13.0 0.7 13 5.4 0.1 2.9 2 0 0 2 2 2 0 NTPase Septin PF00735.13 GAP82594.1 - 0.088 11.7 0.1 5.4 5.9 0.0 2.4 2 0 0 2 2 2 0 Septin ATP-synt_ab PF00006.20 GAP82594.1 - 0.1 12.0 0.4 2.4 7.6 0.0 2.6 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Pox_A32 PF04665.7 GAP82594.1 - 0.15 11.3 3.3 0.61 9.3 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_28 PF13521.1 GAP82594.1 - 0.18 11.7 0.3 12 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 GAP82594.1 - 0.25 11.5 0.2 32 4.7 0.0 2.8 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.17 GAP82594.1 - 0.28 9.9 2.0 5.6 5.7 0.0 3.1 3 1 0 3 3 3 0 NB-ARC domain TrwB_AAD_bind PF10412.4 GAP82594.1 - 0.88 8.1 4.3 2.7 6.5 0.1 2.6 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain DAP3 PF10236.4 GAP82594.1 - 1.2 8.0 3.2 19 4.0 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 CUE PF02845.11 GAP82595.1 - 0.16 11.5 0.3 4.2 6.9 0.1 2.5 2 0 0 2 2 2 0 CUE domain PRP38_assoc PF12871.2 GAP82596.1 - 0.0013 19.2 41.2 0.0013 19.2 28.5 4.0 1 1 2 3 3 3 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term MIP-T3 PF10243.4 GAP82596.1 - 1.3 7.4 29.4 1.6 7.0 20.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Init_tRNA_PT PF04179.7 GAP82597.1 - 1.3e-33 116.5 0.0 1.6e-33 116.2 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Glypican PF01153.14 GAP82597.1 - 0.11 11.1 0.0 0.11 11.1 0.0 1.7 2 0 0 2 2 2 0 Glypican RGM_C PF06534.8 GAP82597.1 - 0.11 11.6 0.5 0.19 10.9 0.0 1.5 2 0 0 2 2 2 0 Repulsive guidance molecule (RGM) C-terminus adh_short PF00106.20 GAP82598.1 - 3.8e-62 209.1 7.9 2.6e-32 112.0 0.8 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 GAP82598.1 - 7.5e-31 107.1 1.6 8.5e-15 54.8 0.1 2.2 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 GAP82598.1 - 2.4e-30 104.4 0.0 4.6e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain Epimerase PF01370.16 GAP82598.1 - 0.0013 18.2 3.8 0.12 11.8 0.1 2.8 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 GAP82598.1 - 0.0015 17.6 0.6 0.018 14.1 0.1 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF4161 PF13722.1 GAP82598.1 - 0.21 11.8 0.7 4.5 7.5 0.0 2.3 2 0 0 2 2 2 0 C-terminal domain on CstA (DUF4161) 3HCDH_N PF02737.13 GAP82598.1 - 4.1 7.0 7.0 3.8 7.1 0.6 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECM11 PF15463.1 GAP82599.1 - 5.9e-38 130.2 0.2 5.9e-38 130.2 0.1 3.4 5 0 0 5 5 5 1 Extracellular mutant protein 11 Acetyltransf_1 PF00583.19 GAP82600.1 - 0.0026 17.7 0.0 0.006 16.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family OrfB_IS605 PF01385.14 GAP82600.1 - 0.017 14.5 0.0 0.023 14.0 0.0 1.1 1 0 0 1 1 1 0 Probable transposase Glyco_transf_90 PF05686.7 GAP82601.1 - 0.057 12.1 0.0 3.4 6.2 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 90 Nucleoplasmin PF03066.10 GAP82601.1 - 0.087 12.3 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin Senescence_reg PF04520.8 GAP82601.1 - 0.1 13.0 2.4 0.16 12.4 1.7 1.2 1 0 0 1 1 1 0 Senescence regulator FAM70 PF14967.1 GAP82601.1 - 4 6.5 6.8 5.4 6.1 4.7 1.1 1 0 0 1 1 1 0 FAM70 protein DUF1517 PF07466.6 GAP82601.1 - 9.1 5.1 8.0 13 4.6 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) MFS_1 PF07690.11 GAP82602.1 - 2e-42 145.1 50.7 4.1e-42 144.1 35.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Aldolase_II PF00596.16 GAP82603.1 - 0.0011 18.6 0.1 0.0015 18.1 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Utp21 PF04192.7 GAP82604.1 - 1.4e-82 276.3 0.1 1.9e-82 275.9 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 GAP82604.1 - 1.7e-24 84.7 16.7 0.00014 21.5 0.1 7.8 9 0 0 9 9 9 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 GAP82604.1 - 6.9e-05 21.3 0.0 0.00012 20.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain PQQ_2 PF13360.1 GAP82604.1 - 0.0045 16.4 0.0 0.27 10.6 0.0 2.9 2 2 0 2 2 2 1 PQQ-like domain Nup160 PF11715.3 GAP82604.1 - 0.0061 14.7 0.1 3.1 5.8 0.0 3.2 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAP82604.1 - 0.014 14.1 0.3 3.8 6.1 0.0 2.7 1 1 0 2 2 2 0 Nup133 N terminal like His_Phos_2 PF00328.17 GAP82605.1 - 4.7e-130 433.9 0.5 6.6e-130 433.4 0.4 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 GAP82605.1 - 8e-07 28.7 0.0 1.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Trefoil PF00088.13 GAP82606.1 - 0.096 12.3 0.8 0.17 11.5 0.1 1.7 2 0 0 2 2 2 0 Trefoil (P-type) domain FGGY_C PF02782.11 GAP82607.1 - 3.1e-13 49.7 0.2 4.2e-13 49.3 0.1 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain MOSC PF03473.12 GAP82608.1 - 1.5e-13 50.3 0.0 3.4e-13 49.2 0.0 1.6 1 1 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 GAP82609.1 - 6.2e-11 42.0 0.0 2.5e-10 40.1 0.0 1.9 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain Glyco_hydro_76 PF03663.9 GAP82610.1 - 5.2e-38 131.3 12.4 1.2e-37 130.2 8.6 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 C5-epim_C PF06662.8 GAP82610.1 - 0.0003 20.1 0.1 0.11 11.7 0.0 2.6 2 0 0 2 2 2 2 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_88 PF07470.8 GAP82610.1 - 0.00051 19.1 0.8 0.2 10.6 0.0 2.4 1 1 0 2 2 2 2 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 GAP82610.1 - 0.0037 15.6 0.1 0.99 7.5 0.0 2.2 1 1 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) TFCD_C PF12612.3 GAP82611.1 - 2.1e-29 102.3 0.8 9.3e-29 100.2 0.1 2.6 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 GAP82611.1 - 0.036 14.1 7.5 1.4 9.1 0.0 6.5 8 0 0 8 8 8 0 HEAT repeat HEAT_2 PF13646.1 GAP82611.1 - 0.86 9.9 13.4 0.77 10.0 0.0 5.7 6 2 1 7 7 7 0 HEAT repeats RNA_pol_Rpb5_C PF01191.14 GAP82614.1 - 8.2e-35 118.2 0.5 1.7e-34 117.2 0.3 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 GAP82614.1 - 1.1e-27 96.2 0.0 2.1e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 GAP82614.1 - 0.0016 18.2 0.0 0.0041 16.9 0.0 1.7 2 0 0 2 2 2 1 Restriction endonuclease Methyltransf_26 PF13659.1 GAP82615.1 - 7.1e-13 48.6 6.7 1.1e-12 47.9 4.4 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP82615.1 - 1.5e-05 24.6 0.0 2.5e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAP82615.1 - 1.7e-05 24.2 0.3 0.046 13.0 0.5 3.1 2 1 0 2 2 2 1 Methyltransferase small domain UPF0020 PF01170.13 GAP82615.1 - 8.9e-05 22.1 0.3 0.016 14.7 0.2 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 GAP82615.1 - 0.0002 21.8 3.4 0.0019 18.7 2.4 2.1 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 GAP82615.1 - 0.0042 16.2 0.1 0.0069 15.5 0.1 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 GAP82615.1 - 0.0046 17.2 0.0 0.0072 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GIDA_assoc_3 PF13932.1 GAP82615.1 - 0.0067 16.4 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 GidA associated domain 3 N6_Mtase PF02384.11 GAP82615.1 - 0.018 14.1 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase Occludin_ELL PF07303.8 GAP82616.1 - 0.035 14.8 4.0 0.035 14.8 2.8 4.9 2 1 2 4 4 4 0 Occludin homology domain Hemagglutinin PF00509.13 GAP82616.1 - 0.49 8.4 11.9 0.22 9.5 1.4 2.3 2 0 0 2 2 2 0 Haemagglutinin Reo_sigmaC PF04582.7 GAP82616.1 - 0.81 8.8 5.1 2.4 7.2 0.1 2.4 2 1 1 3 3 3 0 Reovirus sigma C capsid protein GTP1_OBG PF01018.17 GAP82618.1 - 1.5e-37 128.6 1.7 3.4e-28 98.2 2.2 2.4 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 GAP82618.1 - 7.7e-22 77.4 0.0 1.9e-21 76.2 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAP82618.1 - 7.4e-08 31.8 0.0 3.2e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B ArgK PF03308.11 GAP82618.1 - 0.0068 15.2 0.0 0.2 10.4 0.0 2.4 2 0 0 2 2 2 1 ArgK protein Dynamin_N PF00350.18 GAP82618.1 - 0.012 15.4 0.0 0.1 12.4 0.0 2.5 3 1 0 3 3 3 0 Dynamin family GTP_EFTU PF00009.22 GAP82618.1 - 0.023 14.1 0.0 5.5 6.3 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 GAP82618.1 - 0.03 14.6 0.0 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.1 GAP82618.1 - 0.041 14.1 0.3 0.19 12.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain Arf PF00025.16 GAP82618.1 - 0.056 12.6 0.0 0.2 10.9 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family Dynamin_N PF00350.18 GAP82619.1 - 9.8e-30 103.5 0.6 3e-28 98.7 0.0 2.4 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 GAP82619.1 - 3.1e-13 49.1 0.0 1.1e-12 47.3 0.0 1.9 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 GAP82619.1 - 6.3e-05 22.9 0.0 0.0003 20.7 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 GAP82619.1 - 0.00036 20.3 0.6 0.002 18.0 0.0 2.5 2 0 0 2 2 2 1 Dynamin GTPase effector domain Miro PF08477.8 GAP82619.1 - 0.0033 17.9 0.0 0.01 16.3 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 GAP82619.1 - 0.01 15.2 0.0 0.077 12.4 0.0 2.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 GAP82619.1 - 0.067 12.4 0.2 12 5.1 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Peptidase_S8 PF00082.17 GAP82620.1 - 5.3e-29 101.2 14.4 5.8e-29 101.1 10.0 1.0 1 0 0 1 1 1 1 Subtilase family Orbi_VP6 PF01516.11 GAP82620.1 - 1.5 7.7 4.1 1.8 7.5 2.6 1.3 1 1 0 1 1 1 0 Orbivirus helicase VP6 Aldolase_II PF00596.16 GAP82621.1 - 3.7e-46 157.0 0.0 4.6e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF3148 PF11347.3 GAP82621.1 - 0.017 14.7 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3148) CorA PF01544.13 GAP82622.1 - 4e-05 22.7 0.0 8.4e-05 21.7 0.0 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Nol1_Nop2_Fmu PF01189.12 GAP82623.1 - 1e-42 146.4 0.0 1.1e-21 77.4 0.0 4.1 3 1 1 4 4 4 3 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 GAP82623.1 - 0.00054 19.9 0.0 0.00098 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 GAP82623.1 - 0.069 13.1 0.0 0.23 11.4 0.0 1.9 1 1 0 1 1 1 0 FtsJ-like methyltransferase Cupin_5 PF06172.6 GAP82624.1 - 6.9e-31 107.0 0.0 9.2e-31 106.6 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Mucin PF01456.12 GAP82624.1 - 2.9 7.6 17.1 2.9 7.6 9.2 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein GTP_EFTU PF00009.22 GAP82625.1 - 1.8e-52 177.5 0.0 3.1e-52 176.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 GAP82625.1 - 3e-18 65.4 0.0 8.6e-18 63.9 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 GAP82625.1 - 8.4e-13 48.0 0.0 2.7e-05 23.9 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 GAP82625.1 - 1.3e-05 25.1 0.0 4.3e-05 23.5 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 GAP82625.1 - 0.082 13.4 0.0 0.21 12.0 0.0 1.7 2 0 0 2 2 2 0 Miro-like protein Vps5 PF09325.5 GAP82626.1 - 1e-16 60.9 2.0 1.4e-16 60.4 1.4 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 GAP82626.1 - 3.8e-07 29.8 0.0 8.8e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 PX domain NST1 PF13945.1 GAP82626.1 - 0.19 11.7 2.7 0.39 10.7 1.9 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF605 PF04652.11 GAP82626.1 - 6.8 5.9 19.2 13 5.0 13.3 1.4 1 0 0 1 1 1 0 Vta1 like CorA PF01544.13 GAP82627.1 - 0.00013 21.1 3.6 0.00032 19.8 2.5 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein ADH_N PF08240.7 GAP82628.1 - 2.7e-27 94.6 1.6 5.3e-27 93.7 1.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAP82628.1 - 1.8e-15 56.6 0.1 5e-12 45.5 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ThiF PF00899.16 GAP82628.1 - 0.016 15.0 0.7 0.032 14.0 0.5 1.4 1 0 0 1 1 1 0 ThiF family UDPG_MGDP_dh_N PF03721.9 GAP82628.1 - 0.028 13.8 0.2 0.18 11.1 0.2 2.2 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 GAP82628.1 - 0.04 14.0 0.1 0.089 12.8 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 GAP82628.1 - 0.052 13.6 0.0 0.087 12.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Cpn10 PF00166.16 GAP82628.1 - 0.13 12.1 0.3 2.5 8.0 0.1 2.4 2 0 0 2 2 2 0 Chaperonin 10 Kd subunit 3HCDH_N PF02737.13 GAP82628.1 - 0.15 11.6 1.3 0.27 10.8 0.9 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Herpes_capsid PF06112.6 GAP82628.1 - 9.2 6.2 8.8 19 5.2 6.1 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein FAA_hydrolase PF01557.13 GAP82629.1 - 5.4e-21 75.0 0.0 8.2e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family JAB PF01398.16 GAP82630.1 - 2.9e-08 33.4 0.0 6.8e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 GAP82630.1 - 0.0002 21.4 0.0 0.002 18.2 0.0 2.4 2 1 0 2 2 2 1 Maintenance of mitochondrial structure and function Glyco_hydro_28 PF00295.12 GAP82632.1 - 5.5e-49 166.8 1.4 7.5e-49 166.4 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 adh_short_C2 PF13561.1 GAP82632.1 - 8.8e-18 64.9 0.0 1.5e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAP82632.1 - 4.2e-14 52.7 2.2 6.2e-14 52.2 0.5 1.9 2 0 0 2 2 2 1 short chain dehydrogenase PE PF00934.15 GAP82632.1 - 7.3 6.7 8.1 0.44 10.6 1.3 2.2 2 0 0 2 2 2 0 PE family Trm112p PF03966.11 GAP82634.1 - 0.088 13.1 0.0 0.097 13.0 0.0 1.1 1 0 0 1 1 1 0 Trm112p-like protein IU_nuc_hydro PF01156.14 GAP82636.1 - 8.8e-53 179.5 0.0 5.6e-52 176.8 0.0 1.8 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Peptidase_C69 PF03577.10 GAP82636.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C69 Alpha-amylase PF00128.19 GAP82638.1 - 2.6e-66 224.1 0.1 3.3e-66 223.8 0.1 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CBM_20 PF00686.14 GAP82638.1 - 7e-34 115.3 0.4 1.6e-33 114.1 0.3 1.6 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.6 GAP82638.1 - 2.4e-18 66.0 0.0 6.8e-18 64.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) hDGE_amylase PF14701.1 GAP82638.1 - 0.099 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme DSBA PF01323.15 GAP82639.1 - 1.1e-05 25.1 0.0 1.3e-05 24.9 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Fungal_trans PF04082.13 GAP82640.1 - 2e-16 59.6 0.6 3.9e-16 58.7 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP82640.1 - 4.3e-08 32.9 11.1 6.8e-08 32.2 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 GAP82640.1 - 1.4 9.1 7.4 2.8 8.1 5.1 1.4 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Cu-oxidase_3 PF07732.10 GAP82641.1 - 3.1e-44 149.4 6.7 2.3e-42 143.4 0.4 3.9 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 GAP82641.1 - 1.9e-37 127.8 1.9 4.1e-33 113.8 0.1 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 GAP82641.1 - 1e-28 100.2 0.0 1.4e-27 96.5 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase FPN1 PF06963.7 GAP82642.1 - 1.2e-82 277.6 15.5 2.1e-61 207.6 3.4 2.0 2 0 0 2 2 2 2 Ferroportin1 (FPN1) FSH1 PF03959.8 GAP82643.1 - 3.8e-31 108.1 0.0 4.5e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 GAP82643.1 - 1.7e-07 31.3 0.8 0.00062 19.7 0.1 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP82643.1 - 0.0048 16.6 0.0 0.0072 16.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_M19 PF01244.16 GAP82644.1 - 3e-51 174.2 0.0 3.3e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) TPR_12 PF13424.1 GAP82647.1 - 2.4e-21 75.4 2.7 5.5e-09 35.8 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 GAP82647.1 - 1.6e-13 50.0 3.6 0.0079 16.0 0.0 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAP82647.1 - 5.6e-12 45.9 0.4 0.0024 18.4 0.0 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAP82647.1 - 3.7e-11 42.0 0.2 0.52 10.3 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAP82647.1 - 3.6e-10 38.8 0.5 0.5 10.2 0.2 5.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 GAP82647.1 - 7.4e-10 38.3 0.2 0.00027 20.5 0.0 3.5 2 1 2 4 4 4 3 TPR repeat Apc3 PF12895.2 GAP82647.1 - 1.6e-09 37.7 0.2 0.0032 17.5 0.0 4.1 2 1 2 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 AAA_22 PF13401.1 GAP82647.1 - 9.3e-09 35.5 0.0 4.1e-08 33.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain TPR_19 PF14559.1 GAP82647.1 - 1.7e-08 34.6 1.0 0.00056 20.1 0.0 3.8 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 GAP82647.1 - 1e-06 28.8 0.1 0.32 11.7 0.1 4.7 3 2 1 4 4 4 2 Tetratricopeptide repeat NB-ARC PF00931.17 GAP82647.1 - 0.00011 21.2 0.0 0.00025 20.0 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain DUF900 PF05990.7 GAP82647.1 - 0.00024 20.4 0.0 0.00045 19.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) TPR_20 PF14561.1 GAP82647.1 - 0.00043 20.3 1.0 6.1 7.0 0.1 4.7 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAP82647.1 - 0.00055 20.2 0.0 10 6.8 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat PGAP1 PF07819.8 GAP82647.1 - 0.00073 19.1 0.0 0.015 14.8 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein TPR_8 PF13181.1 GAP82647.1 - 0.0016 18.0 0.0 32 4.6 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF676 PF05057.9 GAP82647.1 - 0.0035 16.6 0.1 0.018 14.3 0.0 2.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 GAP82647.1 - 0.018 14.8 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family NACHT PF05729.7 GAP82647.1 - 0.021 14.5 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.1 GAP82647.1 - 0.1 11.9 0.0 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 GAP82647.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.12 GAP82647.1 - 0.12 11.8 0.2 0.32 10.3 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein TPR_4 PF07721.9 GAP82647.1 - 1.1 9.8 4.8 1.8 9.1 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_10 PF00331.15 GAP82648.1 - 1.1e-39 136.4 0.0 1.2e-39 136.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Solute_trans_a PF03619.11 GAP82649.1 - 7.3e-78 261.6 21.5 8.6e-78 261.4 14.9 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF1422 PF07226.6 GAP82649.1 - 3.9 7.2 8.8 5.8 6.6 0.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1422) PrgI PF12666.2 GAP82649.1 - 4.3 7.5 12.2 0.066 13.3 0.7 2.9 2 1 2 4 4 4 0 PrgI family protein Cation_efflux PF01545.16 GAP82649.1 - 5.9 5.8 9.3 2.2 7.3 1.9 2.4 2 1 0 2 2 2 0 Cation efflux family Isochorismatase PF00857.15 GAP82650.1 - 1e-21 77.6 0.0 1.4e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Myb_DNA-binding PF00249.26 GAP82651.1 - 1.5e-31 108.2 12.1 2.6e-11 43.3 0.3 3.9 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAP82651.1 - 2.9e-31 107.3 15.0 8.5e-14 51.4 0.3 4.1 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 GAP82651.1 - 0.015 15.0 2.4 0.24 11.2 1.2 3.3 2 1 0 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_5 PF13873.1 GAP82651.1 - 0.063 13.1 7.6 2.2 8.2 0.2 3.9 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.3 GAP82651.1 - 0.074 12.9 10.2 0.51 10.2 0.4 3.3 1 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain adh_short PF00106.20 GAP82652.1 - 3.9e-20 72.4 0.0 7e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP82652.1 - 2.1e-08 34.2 0.0 2.4e-06 27.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAP82652.1 - 1.1e-05 24.9 0.0 1.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 GAP82652.1 - 0.00045 19.9 0.0 0.00069 19.3 0.0 1.2 1 0 0 1 1 1 1 KR domain ABM PF03992.11 GAP82653.1 - 3.9e-05 23.5 0.8 7.8e-05 22.6 0.5 1.4 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase GFA PF04828.9 GAP82654.1 - 5.5e-20 71.1 1.8 7.1e-20 70.7 1.3 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-4CXXC_R1 PF10497.4 GAP82654.1 - 0.13 12.4 3.8 0.17 11.9 2.6 1.3 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Prim_Zn_Ribbon PF08273.7 GAP82654.1 - 2.6 8.1 8.5 4.4 7.4 1.0 2.5 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase MFS_1 PF07690.11 GAP82656.1 - 2e-38 132.0 77.0 8.8e-36 123.3 37.0 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3784 PF12650.2 GAP82656.1 - 0.063 13.2 0.4 0.063 13.2 0.3 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3784) WSC PF01822.14 GAP82657.1 - 2.3e-11 43.4 9.6 2.3e-11 43.4 6.7 2.1 2 1 0 2 2 2 1 WSC domain SKG6 PF08693.5 GAP82657.1 - 8.3e-05 21.8 0.1 0.00022 20.4 0.1 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Cuticle_2 PF08184.6 GAP82657.1 - 0.029 14.1 0.1 0.1 12.4 0.0 1.9 1 0 0 1 1 1 0 Cuticle protein 7 isoform family VSP PF03302.8 GAP82657.1 - 0.045 12.3 18.1 0.066 11.8 12.5 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF4229 PF14012.1 GAP82657.1 - 0.06 13.2 1.0 0.21 11.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) DUF4231 PF14015.1 GAP82657.1 - 0.8 9.7 4.4 0.15 12.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF347 PF03988.7 GAP82657.1 - 9.2 6.2 9.8 1.2 9.0 3.2 2.3 2 1 0 2 2 2 0 Repeat of Unknown Function (DUF347) Abhydrolase_3 PF07859.8 GAP82658.1 - 2.3e-06 27.3 7.2 4.1e-06 26.5 5.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 GAP82658.1 - 5.1e-06 25.4 2.3 8.2e-06 24.8 1.6 1.3 1 0 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 GAP82658.1 - 7.1e-05 21.6 0.0 0.00012 20.8 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 GAP82658.1 - 0.0002 21.1 3.9 0.00032 20.4 2.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Kelch_4 PF13418.1 GAP82659.1 - 0.0046 16.7 8.7 0.055 13.2 0.3 4.0 4 0 0 4 4 4 2 Galactose oxidase, central domain BAF1_ABF1 PF04684.8 GAP82659.1 - 2.8 6.7 17.1 4.4 6.0 11.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Filament PF00038.16 GAP82660.1 - 9e-05 22.0 58.9 0.0034 16.9 11.8 4.5 4 1 0 4 4 4 3 Intermediate filament protein Reo_sigmaC PF04582.7 GAP82660.1 - 0.006 15.8 14.6 1.3 8.0 0.4 4.3 3 1 1 4 4 4 3 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 GAP82660.1 - 0.017 14.9 0.3 0.017 14.9 0.2 8.2 8 2 0 8 8 8 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 GAP82660.1 - 0.86 9.1 78.6 1.4 8.5 5.9 6.0 3 2 1 5 5 5 0 IncA protein DUF221 PF02714.10 GAP82661.1 - 7.1e-102 340.5 25.8 1.7e-101 339.3 17.9 1.7 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 GAP82661.1 - 2.7e-45 153.7 2.0 2.7e-45 153.7 1.4 3.1 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 GAP82661.1 - 3.7e-30 103.6 0.2 1e-29 102.2 0.1 1.8 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 GAP82661.1 - 9.3e-22 77.3 0.3 1.6e-21 76.6 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_1 PF00076.17 GAP82661.1 - 0.096 12.3 0.1 0.25 10.9 0.1 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) E1_DerP2_DerF2 PF02221.10 GAP82662.1 - 1.1e-25 90.4 0.8 1.3e-25 90.2 0.5 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 GAP82662.1 - 0.00083 19.4 0.2 0.011 15.8 0.1 2.2 1 1 0 1 1 1 1 ML-like domain Asparaginase PF00710.15 GAP82663.1 - 3.5e-62 210.0 0.0 3.8e-62 209.9 0.0 1.0 1 0 0 1 1 1 1 Asparaginase ATP-synt_F PF01990.12 GAP82664.1 - 4.9e-32 110.1 0.1 5.7e-32 109.9 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.1 GAP82664.1 - 0.031 13.2 0.0 0.031 13.2 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase DUF2418 PF10332.4 GAP82665.1 - 1.7e-32 111.6 0.2 3.2e-32 110.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) CHCH PF06747.8 GAP82667.1 - 0.00021 21.1 6.9 0.00025 20.8 3.6 1.8 1 1 1 2 2 2 2 CHCH domain GCK PF07802.6 GAP82667.1 - 0.0023 17.9 0.5 0.0048 16.9 0.3 1.6 1 1 0 1 1 1 1 GCK domain DUF2076 PF09849.4 GAP82667.1 - 0.014 15.4 1.6 0.014 15.4 1.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) COX6B PF02297.12 GAP82667.1 - 0.1 12.6 2.5 0.14 12.2 1.7 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Nop14 PF04147.7 GAP82668.1 - 0.0044 15.0 22.2 0.0057 14.6 15.4 1.2 1 0 0 1 1 1 1 Nop14-like family RskA PF10099.4 GAP82668.1 - 0.078 12.7 6.3 2 8.1 4.7 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA PPP4R2 PF09184.6 GAP82668.1 - 1.4 8.3 20.2 0.2 11.1 8.6 2.1 2 0 0 2 2 2 0 PPP4R2 DUF2457 PF10446.4 GAP82668.1 - 3 6.4 44.1 0.31 9.7 23.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Ank_2 PF12796.2 GAP82669.1 - 9.4e-51 170.1 0.0 1.6e-19 70.0 0.0 8.9 5 3 2 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 GAP82669.1 - 1e-37 126.0 22.7 6e-07 28.9 0.0 13.6 15 0 0 15 15 15 9 Ankyrin repeat Ank_3 PF13606.1 GAP82669.1 - 2.4e-31 104.6 17.9 0.00019 21.3 0.1 14.7 15 0 0 15 15 15 8 Ankyrin repeat Ank_4 PF13637.1 GAP82669.1 - 3e-29 100.8 5.8 1.9e-07 31.3 0.0 10.1 9 3 4 13 13 13 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP82669.1 - 4.1e-28 96.7 7.6 1.9e-07 31.0 0.0 10.6 8 1 2 10 10 10 6 Ankyrin repeats (many copies) F-box-like PF12937.2 GAP82669.1 - 0.0001 21.9 0.1 0.00037 20.1 0.0 2.0 2 0 0 2 2 2 1 F-box-like Aconitase PF00330.15 GAP82671.1 - 7e-177 588.5 0.0 8.4e-177 588.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 GAP82671.1 - 1e-43 148.6 0.0 1.7e-43 147.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain TPR_11 PF13414.1 GAP82672.1 - 0.0088 15.6 5.8 0.3 10.7 0.1 3.3 4 0 0 4 4 4 2 TPR repeat TPR_14 PF13428.1 GAP82672.1 - 0.1 13.2 0.3 0.1 13.2 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAP82672.1 - 0.27 11.2 0.1 0.27 11.2 0.1 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAP82672.1 - 1.1 9.2 5.2 1.4 8.8 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAP82672.1 - 1.6 9.3 8.3 0.77 10.3 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAP82672.1 - 2.4 8.9 15.6 1.1 10.0 0.5 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Init_tRNA_PT PF04179.7 GAP82673.1 - 4.2e-62 210.4 0.0 5.4e-62 210.1 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase ketoacyl-synt PF00109.21 GAP82674.1 - 9.4e-80 267.7 0.0 1.7e-79 266.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAP82674.1 - 1.2e-48 166.1 0.0 1.8e-48 165.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAP82674.1 - 3.5e-35 120.4 0.2 7.8e-35 119.3 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 GAP82674.1 - 2.1e-23 82.9 0.0 3.5e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.15 GAP82674.1 - 3.4e-23 83.0 0.0 9.6e-23 81.6 0.0 1.8 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 GAP82674.1 - 1.9e-12 47.2 1.9 1.5e-07 31.5 0.1 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 GAP82674.1 - 1.3e-09 38.3 0.1 2.1e-07 31.0 0.0 3.2 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP82674.1 - 1.1e-06 28.4 0.0 0.02 14.6 0.0 2.6 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 GAP82674.1 - 0.0001 21.4 0.0 0.0002 20.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_3 PF07859.8 GAP82674.1 - 0.15 11.5 0.0 0.45 10.0 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold AMP-binding PF00501.23 GAP82675.1 - 2.4e-35 121.7 0.0 8.3e-35 119.9 0.0 1.8 1 1 1 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 GAP82675.1 - 3.9e-12 45.6 0.0 8.1e-12 44.5 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 GAP82675.1 - 9.8e-07 28.9 0.0 3.2e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site HET PF06985.6 GAP82676.1 - 4.6e-34 117.5 0.1 7.2e-34 116.9 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PhyH PF05721.8 GAP82678.1 - 0.074 13.0 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) FAD_binding_3 PF01494.14 GAP82679.1 - 7.9e-44 150.1 0.0 2.6e-43 148.4 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 GAP82679.1 - 0.00025 20.6 0.0 0.0011 18.6 0.0 1.9 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Methyltransf_2 PF00891.13 GAP82680.1 - 1.8e-29 102.6 0.0 3.4e-29 101.7 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 GAP82680.1 - 0.0013 19.2 0.0 0.0033 17.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP82680.1 - 0.0023 17.6 0.0 0.0044 16.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP82680.1 - 0.025 14.1 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Dimerisation PF08100.6 GAP82680.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain B-block_TFIIIC PF04182.7 GAP82680.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC adh_short PF00106.20 GAP82681.1 - 1.5e-10 41.2 2.1 6.9e-10 39.0 1.4 1.8 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 GAP82681.1 - 2.1e-05 24.6 1.4 3.3e-05 23.9 0.8 1.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 GAP82681.1 - 0.00031 20.6 0.0 0.0005 19.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.12 GAP82681.1 - 0.028 13.3 0.1 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain S-AdoMet_synt_C PF02773.11 GAP82682.1 - 2.6e-72 241.0 0.2 3.8e-72 240.4 0.1 1.2 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 GAP82682.1 - 6.2e-44 148.7 0.0 1.3e-43 147.7 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 GAP82682.1 - 2.2e-43 146.5 0.1 4.3e-43 145.6 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Methyltransf_24 PF13578.1 GAP82683.1 - 4.8e-07 30.5 0.0 8.1e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 GAP82683.1 - 2e-06 27.0 0.0 2.9e-06 26.4 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 GAP82683.1 - 8.2e-05 23.1 0.1 0.00019 21.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP82683.1 - 0.0025 17.8 0.2 0.0045 17.0 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain ATP_bind_1 PF03029.12 GAP82684.1 - 9e-69 231.6 0.0 4.1e-68 229.4 0.0 1.8 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 GAP82684.1 - 1.7e-05 25.6 0.0 4.6e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAP82684.1 - 0.0018 18.1 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 GAP82684.1 - 0.003 17.4 0.0 0.0054 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 GAP82684.1 - 0.004 16.6 0.0 0.0079 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_31 PF13614.1 GAP82684.1 - 0.0065 16.4 0.1 0.021 14.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 GAP82684.1 - 0.0077 16.3 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TRADD_N PF09034.5 GAP82684.1 - 0.0099 15.8 0.1 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 TRADD, N-terminal domain AAA_10 PF12846.2 GAP82684.1 - 0.019 14.3 0.0 0.049 13.0 0.0 1.7 1 1 1 2 2 2 0 AAA-like domain AAA_19 PF13245.1 GAP82684.1 - 0.025 14.3 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 GAP82684.1 - 0.027 14.6 0.0 0.052 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.10 GAP82684.1 - 0.029 13.3 0.0 0.054 12.5 0.0 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase FtsK_SpoIIIE PF01580.13 GAP82684.1 - 0.038 13.4 0.0 0.23 10.9 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.1 GAP82684.1 - 0.043 13.7 0.0 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain CbiA PF01656.18 GAP82684.1 - 0.047 13.0 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.22 GAP82684.1 - 0.048 13.9 0.0 0.14 12.4 0.0 1.7 2 0 0 2 2 2 0 ABC transporter IstB_IS21 PF01695.12 GAP82684.1 - 0.067 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein MMR_HSR1 PF01926.18 GAP82684.1 - 0.076 12.9 0.0 0.2 11.6 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 GAP82684.1 - 0.077 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Septin PF00735.13 GAP82684.1 - 0.091 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_18 PF13238.1 GAP82684.1 - 0.13 12.5 0.5 0.84 9.9 0.0 2.4 2 2 0 2 2 2 0 AAA domain Apq12 PF12716.2 GAP82685.1 - 3.3e-07 29.8 9.5 6.2e-07 29.0 6.6 1.5 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis DUF4131 PF13567.1 GAP82685.1 - 0.35 10.2 6.0 0.47 9.8 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Pro-kuma_activ PF09286.6 GAP82686.1 - 2.1e-47 160.7 0.0 3.4e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain AAA PF00004.24 GAP82687.1 - 1.5e-41 141.7 0.6 8.3e-14 51.9 0.0 5.4 6 0 0 6 6 5 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.1 GAP82687.1 - 6e-38 130.2 0.0 1.5e-37 128.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAP82687.1 - 1.6e-25 90.0 23.9 1.1e-24 87.2 0.0 6.6 6 2 0 6 6 5 2 AAA domain AAA_19 PF13245.1 GAP82687.1 - 9.5e-15 54.1 7.4 0.00014 21.5 0.0 5.0 4 0 0 4 4 4 4 Part of AAA domain AAA_22 PF13401.1 GAP82687.1 - 1.2e-12 48.0 13.3 0.017 15.2 0.4 8.6 4 3 1 6 6 6 3 AAA domain AAA_5 PF07728.9 GAP82687.1 - 1.1e-10 41.3 2.2 0.75 9.5 0.0 5.3 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 GAP82687.1 - 5.5e-10 39.6 4.9 0.078 13.2 0.0 5.5 5 0 0 5 5 4 3 AAA domain AAA_17 PF13207.1 GAP82687.1 - 2.1e-09 38.2 16.9 0.044 14.5 0.0 6.4 6 0 0 6 6 5 4 AAA domain Mg_chelatase PF01078.16 GAP82687.1 - 1.1e-07 31.2 2.4 0.2 10.7 0.0 4.8 5 0 0 5 5 5 2 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.13 GAP82687.1 - 1.1e-06 28.3 1.1 0.48 9.8 0.0 5.3 6 0 0 6 6 6 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 GAP82687.1 - 1.2e-06 28.6 1.7 2.5 8.2 0.0 5.0 5 0 0 5 5 4 1 RNA helicase IstB_IS21 PF01695.12 GAP82687.1 - 8.8e-06 25.2 1.4 1.5 8.1 0.0 4.9 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_16 PF13191.1 GAP82687.1 - 0.00011 22.2 24.8 0.5 10.3 0.0 7.0 7 0 0 7 7 5 4 AAA ATPase domain AAA_25 PF13481.1 GAP82687.1 - 0.00045 19.6 4.2 0.51 9.7 0.0 5.4 5 0 0 5 5 5 1 AAA domain AAA_24 PF13479.1 GAP82687.1 - 0.011 15.2 16.0 3.9 7.0 0.3 5.5 5 0 0 5 5 5 0 AAA domain DUF2075 PF09848.4 GAP82687.1 - 0.038 12.9 0.0 0.038 12.9 0.0 5.9 6 2 0 6 6 5 0 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.1 GAP82687.1 - 0.052 13.6 0.0 0.4 10.8 0.0 2.5 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain KaiC PF06745.8 GAP82687.1 - 0.14 11.2 4.1 3.9 6.5 0.0 3.7 4 0 0 4 4 4 0 KaiC Guanylate_cyc_2 PF09778.4 GAP82687.1 - 0.21 10.7 0.0 7.1 5.7 0.0 2.6 3 0 0 3 3 3 0 Guanylylate cyclase MobB PF03205.9 GAP82687.1 - 0.95 9.1 2.5 37 3.9 0.1 3.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Myb_DNA-bind_6 PF13921.1 GAP82688.1 - 0.0044 17.0 0.5 0.0084 16.2 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain HTH_AsnC-type PF13404.1 GAP82688.1 - 0.053 13.0 0.5 0.13 11.8 0.1 1.9 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain SLEI_Leptospira PF07620.6 GAP82689.1 - 0.54 10.1 2.7 7.5 6.5 0.0 3.1 4 0 0 4 4 4 0 SLEI IBR PF01485.16 GAP82690.1 - 1.6e-14 53.5 15.1 5.8e-08 32.4 8.3 2.3 2 0 0 2 2 2 2 IBR domain zf-CSL PF05207.8 GAP82690.1 - 0.41 10.1 7.1 8.7 5.9 2.2 3.2 2 1 1 3 3 3 0 CSL zinc finger Hydrolase_3 PF08282.7 GAP82691.1 - 9.4e-11 41.7 0.0 1.3e-09 38.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PMM PF03332.8 GAP82691.1 - 4.3e-07 29.7 0.0 6.6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase S6PP PF05116.8 GAP82691.1 - 0.0038 16.5 0.0 0.031 13.5 0.0 2.2 3 0 0 3 3 3 1 Sucrose-6F-phosphate phosphohydrolase ISN1 PF06437.6 GAP82691.1 - 0.01 14.5 0.0 0.098 11.3 0.0 1.9 2 0 0 2 2 2 0 IMP-specific 5'-nucleotidase HAD_2 PF13419.1 GAP82691.1 - 0.015 15.5 0.0 7.9 6.6 0.0 2.7 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.11 GAP82691.1 - 0.029 13.2 0.0 0.043 12.7 0.0 1.4 1 1 0 1 1 1 0 Trehalose-phosphatase Hydrolase PF00702.21 GAP82691.1 - 0.03 14.7 0.0 0.048 14.0 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 GAP82691.1 - 0.067 12.8 0.0 7.4 6.1 0.0 2.3 2 0 0 2 2 2 0 Acid Phosphatase C1_3 PF07649.7 GAP82692.1 - 0.18 11.8 10.3 0.34 11.0 7.1 1.5 1 0 0 1 1 1 0 C1-like domain zf-B_box PF00643.19 GAP82692.1 - 0.41 10.5 12.8 0.68 9.8 8.9 1.3 1 0 0 1 1 1 0 B-box zinc finger Hairpins PF04877.7 GAP82693.1 - 0.027 13.8 0.0 0.04 13.3 0.0 1.1 1 0 0 1 1 1 0 HrpZ PP2C PF00481.16 GAP82694.1 - 7.8e-38 130.3 0.0 1.3e-37 129.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 GAP82694.1 - 0.00022 20.6 0.0 0.00039 19.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 GAP82694.1 - 0.12 12.0 0.0 4 7.1 0.0 2.7 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) Glyoxalase PF00903.20 GAP82695.1 - 3.9e-07 30.0 0.0 9.8e-07 28.7 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAP82695.1 - 3.2e-05 24.4 0.3 9.9e-05 22.9 0.2 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain DEC-1_N PF04625.8 GAP82695.1 - 0.037 12.7 7.7 0.038 12.6 5.4 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region CDK2AP PF09806.4 GAP82695.1 - 0.038 14.2 3.0 0.042 14.0 2.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein PepSY_2 PF13670.1 GAP82695.1 - 1.1 9.2 8.7 2.4 8.1 6.1 1.6 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain MSP1_C PF07462.6 GAP82695.1 - 5.3 5.3 6.9 6.2 5.0 4.8 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Med3 PF11593.3 GAP82695.1 - 6.2 5.9 7.3 7.8 5.6 5.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2828 PF11443.3 GAP82696.1 - 0.023 12.9 0.5 0.03 12.5 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) U79_P34 PF03064.11 GAP82696.1 - 0.13 11.7 7.5 0.36 10.2 5.2 1.7 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Ribonuclease_3 PF00636.21 GAP82698.1 - 8e-43 145.5 0.0 3.8e-21 75.6 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 GAP82698.1 - 1.8e-26 92.6 0.0 2.3e-11 43.7 0.0 3.7 3 1 0 3 3 3 3 Ribonuclease-III-like Helicase_C PF00271.26 GAP82698.1 - 2.1e-18 65.9 0.0 5.8e-18 64.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 GAP82698.1 - 8.4e-17 60.7 0.2 4.6e-16 58.3 0.0 2.2 2 0 0 2 2 2 1 Dicer dimerisation domain ResIII PF04851.10 GAP82698.1 - 1.2e-13 51.2 0.2 1.2e-13 51.2 0.1 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 GAP82698.1 - 2.9e-13 49.6 0.0 5.5e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 GAP82698.1 - 0.00065 18.7 0.0 0.0012 17.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 GAP82698.1 - 0.0094 16.0 0.7 0.053 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain FAM74 PF15026.1 GAP82698.1 - 0.092 12.3 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 FAM74 protein SNF2_N PF00176.18 GAP82698.1 - 0.13 10.9 0.1 0.47 9.2 0.0 1.6 1 1 0 1 1 1 0 SNF2 family N-terminal domain TAP42 PF04177.7 GAP82699.1 - 6.5e-102 340.9 0.0 7.3e-102 340.7 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family Bcr-Abl_Oligo PF09036.5 GAP82699.1 - 0.074 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain HHH PF00633.18 GAP82700.1 - 0.026 14.2 0.0 0.06 13.0 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif HhH-GPD PF00730.20 GAP82700.1 - 0.045 14.0 0.0 0.093 13.0 0.0 1.5 1 1 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein CDC73 PF05179.9 GAP82701.1 - 2.4e-48 164.8 0.4 6.6e-48 163.4 0.3 1.6 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family RGS PF00615.14 GAP82702.1 - 4.4e-34 117.1 0.1 1.3e-33 115.5 0.0 1.8 3 0 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.16 GAP82702.1 - 2.4e-22 78.4 0.1 2.1e-18 65.7 0.0 3.1 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ORC4_C PF14629.1 GAP82704.1 - 2.2e-57 193.7 0.0 3.3e-57 193.1 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 GAP82704.1 - 2.4e-12 47.2 0.4 2.9e-11 43.6 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain PHD PF00628.24 GAP82704.1 - 3.6e-10 39.3 6.9 6.1e-10 38.6 4.8 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 GAP82704.1 - 5e-10 38.5 1.7 9e-10 37.7 1.2 1.4 1 0 0 1 1 1 1 PHD-finger AAA_22 PF13401.1 GAP82704.1 - 2.7e-07 30.7 0.1 8.3e-07 29.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA PF00004.24 GAP82704.1 - 5.7e-07 29.8 0.0 1.5e-06 28.4 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 GAP82704.1 - 8.7e-06 25.5 0.0 1.5e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 GAP82704.1 - 0.00035 20.2 0.1 0.0013 18.4 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 GAP82704.1 - 0.0014 18.5 0.1 0.0082 16.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 GAP82704.1 - 0.0023 16.9 0.0 0.0038 16.2 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA_30 PF13604.1 GAP82704.1 - 0.003 17.1 0.0 0.012 15.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain FYVE_2 PF02318.11 GAP82704.1 - 0.0032 17.3 0.2 0.0083 16.0 0.1 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger NB-ARC PF00931.17 GAP82704.1 - 0.0041 16.0 0.0 0.0066 15.3 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain ATP-synt_ab PF00006.20 GAP82704.1 - 0.0093 15.4 0.1 0.048 13.1 0.0 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Prok-RING_1 PF14446.1 GAP82704.1 - 0.012 15.3 2.7 0.025 14.3 1.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 AAA_17 PF13207.1 GAP82704.1 - 0.015 16.1 0.1 0.044 14.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain C1_1 PF00130.17 GAP82704.1 - 0.018 14.7 0.3 0.04 13.6 0.2 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) AAA_28 PF13521.1 GAP82704.1 - 0.037 13.9 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 GAP82704.1 - 0.066 13.7 0.0 0.16 12.5 0.0 1.7 1 1 0 1 1 1 0 Miro-like protein zf-RING_2 PF13639.1 GAP82704.1 - 0.15 11.9 6.6 0.29 10.9 4.5 1.5 1 0 0 1 1 1 0 Ring finger domain AAA_10 PF12846.2 GAP82704.1 - 0.17 11.3 0.4 16 4.8 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain Viral_helicase1 PF01443.13 GAP82704.1 - 0.17 11.3 0.0 0.38 10.2 0.0 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase FAD_binding_3 PF01494.14 GAP82705.1 - 3.3e-09 36.2 0.0 3.8e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAP82705.1 - 3.2e-07 30.2 0.5 6.6e-07 29.2 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAP82705.1 - 3e-06 26.4 0.7 3.9e-06 25.9 0.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAP82705.1 - 2.2e-05 23.5 0.6 2.8e-05 23.1 0.4 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 GAP82705.1 - 3.9e-05 23.9 0.2 5.7e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAP82705.1 - 0.00015 20.9 0.0 0.00021 20.4 0.0 1.1 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 GAP82705.1 - 0.0011 17.6 0.1 0.0014 17.3 0.1 1.1 1 0 0 1 1 1 1 Tryptophan halogenase GIDA PF01134.17 GAP82705.1 - 0.0017 17.3 0.1 0.0021 17.0 0.1 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 GAP82705.1 - 0.002 18.2 0.1 0.0026 17.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAP82705.1 - 0.0029 17.4 0.1 0.0037 17.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 GAP82705.1 - 0.0048 16.4 0.0 0.0066 16.0 0.0 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 GAP82705.1 - 0.005 16.5 0.1 0.0068 16.0 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 GAP82705.1 - 0.021 14.2 0.1 0.026 13.9 0.0 1.1 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 GAP82705.1 - 0.027 12.9 0.1 0.033 12.6 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 GAP82705.1 - 0.054 12.3 0.2 0.072 11.9 0.2 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.11 GAP82705.1 - 0.097 12.1 0.4 0.13 11.6 0.3 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.2 GAP82705.1 - 0.12 11.3 0.3 0.16 10.9 0.2 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 GAP82705.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 GAP82705.1 - 0.14 12.4 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.16 GAP82705.1 - 0.14 11.9 0.3 0.21 11.3 0.2 1.2 1 0 0 1 1 1 0 ThiF family Amino_oxidase PF01593.19 GAP82705.1 - 0.4 9.6 2.5 0.3 10.0 0.2 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Git3 PF11710.3 GAP82707.1 - 2.9e-50 170.6 19.6 4.8e-50 169.9 13.6 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 GAP82707.1 - 6.9e-19 67.3 0.7 1.2e-12 47.4 0.1 2.9 2 0 0 2 2 2 2 G protein-coupled glucose receptor regulating Gpa2 C-term ABC_cobalt PF09819.4 GAP82707.1 - 0.26 11.2 9.4 0.32 10.9 2.5 2.6 1 1 1 2 2 2 0 ABC-type cobalt transport system, permease component K_channel_TID PF07941.6 GAP82707.1 - 0.69 10.1 11.7 0.48 10.6 5.8 2.4 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain GATase PF00117.23 GAP82708.1 - 1.3e-06 28.0 0.4 0.0037 16.7 0.1 2.2 1 1 1 2 2 2 2 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 GAP82708.1 - 0.17 11.2 0.4 1.2 8.5 0.3 2.3 1 1 0 1 1 1 0 Peptidase C26 F-box PF00646.28 GAP82709.1 - 3.4e-07 29.7 0.2 6.5e-07 28.8 0.2 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAP82709.1 - 5.4e-06 26.0 1.0 1.7e-05 24.4 0.1 2.2 2 0 0 2 2 2 1 F-box-like 2OG-FeII_Oxy PF03171.15 GAP82710.1 - 0.011 16.0 0.0 0.015 15.5 0.0 1.2 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 GAP82711.1 - 4e-08 32.3 38.0 4e-08 32.3 26.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily NDUF_B12 PF08122.7 GAP82711.1 - 0.11 12.2 0.0 0.36 10.5 0.0 1.9 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family zf-RING_6 PF14835.1 GAP82713.1 - 0.19 11.5 0.4 0.37 10.6 0.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Sporozoite_P67 PF05642.6 GAP82713.1 - 0.31 8.8 9.2 0.33 8.7 6.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen K_oxygenase PF13434.1 GAP82714.1 - 4.9e-14 51.9 0.0 1.6e-07 30.5 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 GAP82714.1 - 2.3e-12 47.3 0.0 3.4e-05 23.9 0.0 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAP82714.1 - 1e-06 27.8 0.4 0.69 8.7 0.0 3.2 3 0 0 3 3 3 3 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAP82714.1 - 1.8e-05 24.7 0.0 0.063 13.1 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAP82714.1 - 0.00014 21.6 0.0 0.0045 16.7 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 GAP82714.1 - 0.0026 17.8 0.1 0.14 12.2 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 GAP82714.1 - 0.0069 14.9 0.0 0.25 9.7 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 GAP82714.1 - 0.008 16.5 2.6 3.2 8.2 0.1 3.3 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAP82714.1 - 0.0099 14.9 0.2 0.09 11.8 0.0 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 GAP82714.1 - 0.01 14.8 1.4 0.78 8.7 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.1 GAP82714.1 - 0.012 15.5 0.2 0.28 11.2 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAP82714.1 - 0.022 13.6 0.1 0.11 11.3 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_10 PF13460.1 GAP82714.1 - 0.14 12.1 0.2 1.2 9.1 0.0 2.5 3 0 0 3 3 3 0 NADH(P)-binding DUF2196 PF09962.4 GAP82716.1 - 7.6e-21 73.6 3.1 1.2e-20 73.0 2.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) TOBE_2 PF08402.5 GAP82716.1 - 0.022 14.7 0.1 0.055 13.4 0.1 1.8 1 0 0 1 1 1 0 TOBE domain Abhydrolase_3 PF07859.8 GAP82717.1 - 5.8e-44 150.1 0.0 8e-44 149.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP82717.1 - 5.7e-05 22.9 0.0 8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 GAP82717.1 - 0.0002 20.2 0.0 0.0003 19.6 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 GAP82717.1 - 0.00071 19.5 0.1 0.0014 18.6 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAP82717.1 - 0.0027 16.9 0.0 0.018 14.2 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Kinesin PF00225.18 GAP82718.1 - 2.6e-50 171.0 0.0 1.7e-40 138.8 0.0 2.6 2 0 0 2 2 2 2 Kinesin motor domain Ribosomal_S21 PF01165.15 GAP82718.1 - 3.7e-13 48.7 9.6 4.3e-13 48.4 3.7 3.3 3 0 0 3 3 3 1 Ribosomal protein S21 PWI PF01480.12 GAP82719.1 - 3.2e-10 39.9 0.4 8.1e-10 38.6 0.3 1.7 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 GAP82719.1 - 0.002 17.7 0.0 0.0051 16.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ECH PF00378.15 GAP82720.1 - 3e-42 144.4 0.1 2.4e-33 115.2 1.1 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 GAP82720.1 - 0.013 15.3 0.1 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 Glyco_hydro_28 PF00295.12 GAP82721.1 - 5e-43 147.3 1.0 6.5e-43 146.9 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 SDH_alpha PF03313.10 GAP82721.1 - 0.2 10.6 1.3 0.34 9.9 0.9 1.3 1 0 0 1 1 1 0 Serine dehydratase alpha chain SH3_9 PF14604.1 GAP82722.1 - 2.8e-10 39.6 0.0 4.4e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAP82722.1 - 8.6e-08 31.4 0.0 1.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAP82722.1 - 6.7e-07 28.6 0.0 1.2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Herpes_gE PF02480.11 GAP82722.1 - 0.0017 16.7 0.8 0.071 11.3 0.0 2.2 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E Protocadherin PF08374.6 GAP82722.1 - 0.031 13.9 0.0 0.031 13.9 0.0 2.4 2 1 0 2 2 2 0 Protocadherin EphA2_TM PF14575.1 GAP82722.1 - 0.038 14.3 0.0 0.092 13.1 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1191 PF06697.7 GAP82722.1 - 0.054 12.2 0.0 0.079 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) SKG6 PF08693.5 GAP82722.1 - 0.076 12.3 0.1 0.076 12.3 0.1 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Amnionless PF14828.1 GAP82722.1 - 0.16 10.4 0.0 0.23 9.8 0.0 1.1 1 0 0 1 1 1 0 Amnionless Gar1 PF04410.9 GAP82724.1 - 5.4e-37 126.6 0.0 5.4e-37 126.6 0.0 2.6 3 0 0 3 3 3 1 Gar1/Naf1 RNA binding region Glyco_transf_22 PF03901.12 GAP82725.1 - 1.6e-79 267.9 17.8 1.9e-79 267.6 12.3 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Glyco_hydro_43 PF04616.9 GAP82726.1 - 1.8e-28 99.4 0.2 2.5e-28 99.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 HNF-1A_C PF04813.7 GAP82727.1 - 0.033 14.4 0.2 0.048 13.9 0.2 1.3 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus M_domain PF12938.2 GAP82727.1 - 2.3 7.9 7.9 3.1 7.5 5.5 1.3 1 0 0 1 1 1 0 M domain of GW182 CBM_1 PF00734.13 GAP82728.1 - 7.2e-10 38.3 8.4 1.4e-09 37.4 5.8 1.5 1 0 0 1 1 1 1 Fungal cellulose binding domain DNase_NucA_NucB PF14040.1 GAP82729.1 - 1.3e-28 99.4 0.2 2.1e-28 98.7 0.1 1.4 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB CoA_binding_2 PF13380.1 GAP82731.1 - 1.1e-27 96.5 0.1 1.4e-27 96.1 0.1 1.1 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 GAP82731.1 - 0.11 13.0 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 CoA binding domain Methyltransf_11 PF08241.7 GAP82733.1 - 1.6e-16 60.5 0.0 2.8e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP82733.1 - 2.5e-14 53.8 0.0 4.8e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP82733.1 - 1.6e-09 37.4 0.0 2.2e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP82733.1 - 3.3e-09 37.0 0.0 5.8e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP82733.1 - 4e-09 36.8 0.0 6.2e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP82733.1 - 4.2e-08 33.0 0.0 6.6e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP82733.1 - 1.8e-07 31.1 0.5 4.6e-07 29.8 0.3 1.6 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 GAP82733.1 - 0.00027 19.8 0.0 0.00046 19.1 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Ubie_methyltran PF01209.13 GAP82733.1 - 0.0022 17.1 0.0 0.0032 16.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 GAP82733.1 - 0.0024 17.2 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain tRNA_U5-meth_tr PF05958.6 GAP82733.1 - 0.013 14.1 0.0 0.019 13.6 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_24 PF13578.1 GAP82733.1 - 0.025 15.3 0.1 0.083 13.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain NodS PF05401.6 GAP82733.1 - 0.027 13.8 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) RrnaAD PF00398.15 GAP82733.1 - 0.049 12.6 0.0 0.075 12.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 GAP82733.1 - 0.049 13.3 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain EF-hand_7 PF13499.1 GAP82734.1 - 2.2e-14 53.3 0.1 6.9e-09 35.7 0.0 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_9 PF14658.1 GAP82734.1 - 1.5e-10 40.7 0.0 0.00018 21.3 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.1 GAP82734.1 - 2.7e-10 39.2 0.2 2.8e-05 23.6 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 GAP82734.1 - 2.3e-08 32.7 0.1 0.00039 19.5 0.0 3.8 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 GAP82734.1 - 1.1e-07 31.3 0.9 0.00041 19.9 0.0 3.4 2 2 1 3 3 3 2 EF-hand domain pair DUF3216 PF11505.3 GAP82734.1 - 0.14 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Peptidase_M3 PF01432.15 GAP82735.1 - 1e-157 525.8 0.0 1.3e-157 525.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.1 GAP82735.1 - 0.012 15.7 0.0 0.032 14.2 0.0 1.7 1 0 0 1 1 1 0 Effector protein BIR PF00653.16 GAP82736.1 - 4.9e-41 138.9 3.3 1.2e-20 73.6 0.7 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Lactamase_B_3 PF13483.1 GAP82738.1 - 1.6e-05 24.6 0.0 2.9e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.2 GAP82738.1 - 0.013 15.0 0.2 0.058 12.9 0.0 2.2 2 1 0 2 2 2 0 Beta-lactamase superfamily domain nec1 PF10379.4 GAP82740.1 - 0.039 13.2 0.3 0.057 12.6 0.2 1.2 1 0 0 1 1 1 0 Virulence protein nec1 SAC3_GANP PF03399.11 GAP82741.1 - 6.5e-05 22.5 0.3 0.0001 21.9 0.2 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DSPc PF00782.15 GAP82742.1 - 7.7e-12 44.9 0.0 1.5e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Macoilin PF09726.4 GAP82742.1 - 1 7.5 3.3 1.3 7.2 2.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Spo7 PF03907.8 GAP82744.1 - 2.4e-69 233.1 0.0 3.3e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 Spo7-like protein PBP1_TM PF14812.1 GAP82744.1 - 2.6 8.4 6.5 0.44 10.8 1.0 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Abhydrolase_6 PF12697.2 GAP82745.1 - 7.3e-28 98.0 0.7 1.2e-27 97.3 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP82745.1 - 1.7e-15 57.1 0.0 1.6e-12 47.4 0.0 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP82745.1 - 1.1e-12 47.8 0.0 3.8e-11 42.9 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 GAP82745.1 - 4.7e-06 26.2 0.0 1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.6 GAP82745.1 - 5e-05 22.5 0.0 8.9e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 GAP82745.1 - 0.0058 16.2 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.15 GAP82745.1 - 0.0094 16.1 0.0 0.066 13.4 0.0 2.1 1 1 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 GAP82745.1 - 0.011 15.6 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_3 PF07859.8 GAP82745.1 - 0.016 14.7 0.0 0.08 12.5 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold PGAP1 PF07819.8 GAP82745.1 - 0.023 14.2 0.0 0.091 12.3 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein Chlorophyllase2 PF12740.2 GAP82745.1 - 0.025 13.4 0.0 0.049 12.5 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme DLH PF01738.13 GAP82745.1 - 0.029 13.6 0.0 0.36 10.0 0.0 2.4 2 1 0 2 2 2 0 Dienelactone hydrolase family BAAT_C PF08840.6 GAP82745.1 - 0.041 13.5 0.0 0.23 11.1 0.0 2.1 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Ser_hydrolase PF06821.8 GAP82745.1 - 0.05 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_2 PF02230.11 GAP82745.1 - 0.08 12.3 0.0 11 5.4 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF2305 PF10230.4 GAP82745.1 - 0.086 12.2 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) CMD PF02627.15 GAP82746.1 - 3.7e-08 33.1 5.7 3.7e-08 33.1 4.0 2.1 2 1 0 2 2 2 1 Carboxymuconolactone decarboxylase family DUF1996 PF09362.5 GAP82747.1 - 2.2e-62 210.8 3.8 3e-62 210.3 2.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF3405 PF11885.3 GAP82748.1 - 2.3e-115 385.6 0.1 3.1e-115 385.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) SMC_Nse1 PF07574.8 GAP82749.1 - 3.7e-35 121.3 0.0 4.7e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 GAP82749.1 - 1.1e-11 44.4 8.7 1.9e-11 43.7 6.0 1.4 1 0 0 1 1 1 1 RING-like domain FYDLN_acid PF09538.5 GAP82749.1 - 0.0042 17.6 0.5 0.0042 17.6 0.3 2.4 2 0 0 2 2 2 1 Protein of unknown function (FYDLN_acid) FYVE PF01363.16 GAP82749.1 - 0.02 14.7 3.5 0.87 9.5 1.1 2.4 2 0 0 2 2 2 0 FYVE zinc finger PaaX PF07848.7 GAP82749.1 - 0.048 13.6 0.0 0.087 12.8 0.0 1.4 1 0 0 1 1 1 0 PaaX-like protein zf-RING_2 PF13639.1 GAP82749.1 - 0.27 11.0 6.7 0.75 9.6 3.9 2.1 2 0 0 2 2 2 0 Ring finger domain C1_1 PF00130.17 GAP82749.1 - 2.6 7.8 8.1 0.56 9.9 2.0 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4 PF00097.20 GAP82749.1 - 5.4 6.7 6.8 12 5.6 4.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2269 PF10027.4 GAP82750.1 - 0.04 13.7 0.1 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) OAD_gamma PF04277.8 GAP82750.1 - 0.069 13.5 4.3 1.4 9.3 0.0 2.8 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain K_channel_TID PF07941.6 GAP82750.1 - 0.1 12.8 0.3 0.1 12.8 0.2 3.6 5 0 0 5 5 5 0 Potassium channel Kv1.4 tandem inactivation domain DUF2555 PF10742.4 GAP82751.1 - 0.15 11.7 0.7 2 8.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2555) SPRY PF00622.23 GAP82752.1 - 9.9e-07 28.8 0.0 1.9e-05 24.7 0.0 2.9 2 1 0 2 2 2 1 SPRY domain DUF1258 PF06869.7 GAP82753.1 - 0.11 11.5 1.6 0.18 10.8 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) Glyco_hydro_16 PF00722.16 GAP82754.1 - 2.9e-37 127.7 0.3 4.5e-37 127.1 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 ADH_zinc_N PF00107.21 GAP82755.1 - 8.9e-06 25.2 0.1 9.2e-06 25.2 0.1 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PHD PF00628.24 GAP82756.1 - 1.8e-08 33.9 10.7 3.1e-08 33.1 7.4 1.4 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 GAP82756.1 - 0.007 16.0 5.8 0.007 16.0 4.0 1.9 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.1 GAP82756.1 - 0.012 14.9 4.1 0.022 14.0 2.9 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 GAP82756.1 - 0.029 13.6 11.0 0.15 11.4 7.6 2.1 1 1 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 GAP82756.1 - 0.11 12.3 4.7 0.26 11.0 3.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 F5_F8_type_C PF00754.20 GAP82757.1 - 0.00063 19.5 2.2 0.00063 19.5 1.5 2.2 2 0 0 2 2 2 1 F5/8 type C domain HET PF06985.6 GAP82758.1 - 1.7e-19 70.3 0.0 4e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) 2OG-FeII_Oxy_3 PF13640.1 GAP82758.1 - 0.039 14.4 0.0 0.12 12.8 0.0 1.9 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily CoA_transf_3 PF02515.12 GAP82759.1 - 1.2e-57 194.1 0.0 2.1e-57 193.4 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III PEPcase_2 PF14010.1 GAP82759.1 - 0.068 11.4 0.1 0.096 10.9 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase DUF3602 PF12223.3 GAP82760.1 - 0.00025 21.3 0.2 0.0008 19.7 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3602) Shisa PF13908.1 GAP82761.1 - 0.019 15.1 0.2 0.26 11.4 0.0 2.0 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator RCR PF12273.3 GAP82761.1 - 0.052 14.0 0.4 0.052 14.0 0.3 2.2 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF3481 PF11980.3 GAP82761.1 - 0.062 13.1 0.1 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) P12 PF12669.2 GAP82761.1 - 0.069 13.3 0.9 0.11 12.6 0.6 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family Herpes_gE PF02480.11 GAP82761.1 - 0.072 11.3 0.0 0.11 10.6 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 GAP82761.1 - 0.09 11.5 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Neur_chan_memb PF02932.11 GAP82761.1 - 3.3 7.5 4.2 0.97 9.2 0.5 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region TFIIB PF00382.14 GAP82762.1 - 4.1e-32 109.8 1.5 4.2e-20 71.3 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 GAP82762.1 - 6.9e-15 54.0 0.7 3.1e-14 51.9 0.5 2.0 2 0 0 2 2 2 1 TFIIB zinc-binding HTH_Tnp_ISL3 PF13542.1 GAP82762.1 - 0.012 14.7 0.0 0.032 13.3 0.0 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4_2 PF08281.7 GAP82762.1 - 0.024 14.0 0.0 0.059 12.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Med12-LCEWAV PF12145.3 GAP82762.1 - 0.044 12.2 0.3 0.086 11.3 0.2 1.5 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain GerE PF00196.14 GAP82762.1 - 0.073 12.4 0.2 0.2 10.9 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family RB_B PF01857.15 GAP82762.1 - 0.089 12.2 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain HTH_5 PF01022.15 GAP82762.1 - 0.11 12.1 0.0 12 5.6 0.0 2.9 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family zf-ribbon_3 PF13248.1 GAP82762.1 - 0.12 11.6 1.0 0.32 10.2 0.3 2.0 2 0 0 2 2 2 0 zinc-ribbon domain Rrf2 PF02082.15 GAP82762.1 - 0.14 12.3 0.0 24 5.1 0.0 2.6 2 1 0 2 2 2 0 Transcriptional regulator MDMPI_N PF11716.3 GAP82763.1 - 0.88 9.9 9.2 1.9 8.9 3.4 2.4 1 1 1 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain Chitin_bind_3 PF03067.10 GAP82764.1 - 2.4e-06 27.9 0.1 4e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Chitin binding domain CRC_subunit PF08624.5 GAP82766.1 - 5.8e-57 191.4 0.1 8.8e-57 190.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit DUF2890 PF11081.3 GAP82766.1 - 0.68 9.9 7.5 1.4 8.9 5.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Cyclin PF08613.6 GAP82767.1 - 2.4e-09 37.7 0.0 3.7e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 GAP82767.1 - 7.2e-05 22.3 0.0 0.00016 21.2 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Nefa_Nip30_N PF10187.4 GAP82768.1 - 5.4e-21 74.6 9.4 5.4e-21 74.6 6.5 1.6 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 adh_short_C2 PF13561.1 GAP82769.1 - 0.07 12.8 0.0 0.084 12.6 0.0 1.0 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Tim54 PF11711.3 GAP82770.1 - 1.5e-120 402.3 0.2 1.8e-120 402.0 0.1 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DSBA PF01323.15 GAP82771.1 - 6.1e-12 45.5 0.0 3.6e-06 26.6 0.0 2.1 2 0 0 2 2 2 2 DSBA-like thioredoxin domain Pkinase PF00069.20 GAP82772.1 - 2.4e-56 190.7 0.1 1.9e-39 135.3 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAP82772.1 - 1.5e-26 93.0 0.2 1.8e-20 73.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAP82772.1 - 0.00011 21.3 0.4 0.00023 20.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 GAP82772.1 - 0.00021 21.1 3.6 0.018 14.7 0.2 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 GAP82772.1 - 0.00058 18.9 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 GAP82772.1 - 0.04 12.7 0.1 0.061 12.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 GAP82772.1 - 0.069 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 GAP82772.1 - 0.47 9.7 2.4 0.36 10.1 0.0 1.8 2 0 0 2 2 2 0 RIO1 family zf-met PF12874.2 GAP82773.1 - 5.5e-06 26.3 1.6 1e-05 25.5 1.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.6 GAP82773.1 - 0.056 12.7 0.9 0.096 11.9 0.6 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like SKG6 PF08693.5 GAP82774.1 - 2.4e-07 29.9 3.2 4.5e-07 29.0 2.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.7 GAP82774.1 - 0.0012 18.2 0.1 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Herpes_gE PF02480.11 GAP82774.1 - 0.097 10.9 0.2 7.3 4.7 0.1 2.1 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Ldl_recept_b PF00058.12 GAP82774.1 - 0.097 13.0 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Low-density lipoprotein receptor repeat class B Syndecan PF01034.15 GAP82774.1 - 0.27 10.9 1.1 0.38 10.4 0.2 1.7 2 0 0 2 2 2 0 Syndecan domain GFA PF04828.9 GAP82775.1 - 1.8e-07 30.9 1.4 3.8e-07 29.9 1.0 1.5 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NHL PF01436.16 GAP82777.1 - 0.021 14.7 0.0 0.061 13.3 0.0 1.8 1 0 0 1 1 1 0 NHL repeat VCBS PF13517.1 GAP82777.1 - 4.2 7.8 7.5 0.42 11.0 0.4 3.0 4 1 0 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Nitroreductase PF00881.19 GAP82778.1 - 1.7e-26 92.9 0.0 2.8e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family Peptidase_C12 PF01088.16 GAP82779.1 - 1.6e-31 109.2 0.0 1.7e-31 109.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 AAA_16 PF13191.1 GAP82780.1 - 0.00022 21.2 3.1 0.0045 17.0 0.5 3.4 2 2 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 GAP82780.1 - 0.0026 17.1 0.1 0.0066 15.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 GAP82780.1 - 0.0076 15.9 0.0 0.021 14.5 0.0 1.8 1 1 0 1 1 1 1 Archaeal ATPase ATP-synt_ab PF00006.20 GAP82780.1 - 0.013 14.9 0.1 0.065 12.7 0.1 2.1 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF2075 PF09848.4 GAP82780.1 - 0.02 13.9 0.0 0.035 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 GAP82780.1 - 0.022 14.8 0.2 0.022 14.8 0.1 2.1 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 GAP82780.1 - 0.08 12.0 0.1 0.17 10.9 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA PF00004.24 GAP82780.1 - 0.11 12.7 0.5 0.62 10.2 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 GAP82780.1 - 0.12 12.8 0.1 2.9 8.4 0.0 2.9 2 1 1 3 3 3 0 Miro-like protein p450 PF00067.17 GAP82781.1 - 2.3e-46 158.2 0.0 2.9e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FSH1 PF03959.8 GAP82782.1 - 6.2e-25 87.8 0.0 4.1e-24 85.2 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 GAP82782.1 - 0.087 12.6 0.0 0.38 10.5 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family NmrA PF05368.8 GAP82783.1 - 6.3e-41 140.1 0.0 8.5e-41 139.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAP82783.1 - 1.8e-10 41.1 0.0 5.1e-10 39.6 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAP82783.1 - 3.4e-05 22.6 0.0 5e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 GAP82783.1 - 4e-05 23.6 0.0 7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.20 GAP82783.1 - 0.00021 21.2 0.0 0.00036 20.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 GAP82783.1 - 0.00065 19.2 0.0 0.00098 18.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 GAP82783.1 - 0.0026 17.4 0.0 0.0042 16.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.19 GAP82783.1 - 0.0028 17.9 0.0 0.0054 17.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 GAP82783.1 - 0.0035 16.3 0.0 0.012 14.6 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 GAP82783.1 - 0.0042 17.4 0.0 0.0083 16.5 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF3425 PF11905.3 GAP82785.1 - 2.6e-17 63.0 0.2 6.3e-17 61.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Baculo_p74_N PF08404.5 GAP82785.1 - 0.097 11.4 0.0 0.19 10.4 0.0 1.4 1 0 0 1 1 1 0 Baculoviridae P74 N-terminal DUF1295 PF06966.7 GAP82788.1 - 5.7e-12 45.4 0.6 4.8e-11 42.3 0.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 GAP82788.1 - 6.3e-10 38.1 0.2 4.4e-09 35.3 0.1 1.9 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.9 GAP82788.1 - 0.0019 18.3 0.0 0.0029 17.7 0.0 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 GAP82788.1 - 0.075 13.1 0.1 0.16 12.1 0.1 1.7 1 1 0 1 1 1 0 Phospholipid methyltransferase Kelch_5 PF13854.1 GAP82789.1 - 1e-06 28.5 0.1 0.0047 16.8 0.1 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 GAP82789.1 - 0.00077 19.5 1.5 0.061 13.5 0.1 3.0 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 GAP82789.1 - 0.041 14.0 0.6 0.93 9.7 0.0 2.3 2 1 0 2 2 2 0 Kelch motif SNF5 PF04855.7 GAP82790.1 - 1.3e-85 286.8 0.0 1.9e-85 286.2 0.0 1.2 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 GAP82790.1 - 3.8e-05 22.9 3.0 8.8e-05 21.7 2.1 1.7 1 0 0 1 1 1 1 GATA zinc finger Terminase_GpA PF05876.7 GAP82790.1 - 0.11 10.8 0.3 0.19 10.0 0.2 1.3 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) GST_N_3 PF13417.1 GAP82791.1 - 6.7e-09 35.8 0.1 1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAP82791.1 - 7.9e-06 25.7 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAP82791.1 - 0.061 13.4 0.0 0.18 11.9 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Abhydrolase_6 PF12697.2 GAP82793.1 - 3.6e-21 76.0 0.9 1.4e-20 74.1 0.6 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP82793.1 - 5.1e-09 36.0 0.1 0.0032 17.2 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP82793.1 - 7.8e-08 32.1 0.4 2.3e-07 30.6 0.3 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAP82793.1 - 0.058 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Redoxin PF08534.5 GAP82794.1 - 6.3e-09 35.5 0.0 6.5e-09 35.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin FA_hydroxylase PF04116.8 GAP82795.1 - 1.2e-05 25.6 3.4 1.2e-05 25.6 2.4 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Acyl-CoA_dh_M PF02770.14 GAP82796.1 - 0.042 13.3 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain NlpE PF04170.7 GAP82796.1 - 0.13 12.6 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 NlpE N-terminal domain Peptidase_M28 PF04389.12 GAP82797.1 - 1.4e-31 109.6 0.0 2.7e-31 108.7 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.17 GAP82797.1 - 1.7e-13 50.0 0.3 3.8e-13 48.9 0.2 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 GAP82797.1 - 0.00011 21.7 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 ThiF PF00899.16 GAP82798.1 - 2.3e-07 30.7 0.1 6.1e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 ThiF family TPR_12 PF13424.1 GAP82799.1 - 2e-37 126.9 18.6 7.3e-15 54.6 0.1 4.9 3 1 2 5 5 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 GAP82799.1 - 7.9e-34 114.6 28.0 1.2e-09 37.7 0.0 8.7 7 2 2 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.23 GAP82799.1 - 3.4e-11 42.2 6.3 0.0045 16.5 0.1 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAP82799.1 - 7.2e-11 41.0 6.5 0.0093 15.6 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAP82799.1 - 7.6e-11 42.3 11.9 0.00034 21.2 0.0 5.7 4 1 1 5 5 5 3 Tetratricopeptide repeat AAA_22 PF13401.1 GAP82799.1 - 7.7e-10 39.0 0.0 4.2e-09 36.6 0.0 2.3 1 0 0 1 1 1 1 AAA domain TPR_19 PF14559.1 GAP82799.1 - 1.2e-09 38.3 18.9 0.012 15.9 0.1 6.6 3 1 4 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 GAP82799.1 - 5.7e-08 32.1 12.6 0.06 13.2 0.0 6.5 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 GAP82799.1 - 3.8e-07 30.1 20.0 0.73 10.6 0.0 8.1 6 1 2 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAP82799.1 - 1.9e-06 27.4 10.7 0.00032 20.2 0.2 4.5 4 2 1 5 5 3 3 TPR repeat TPR_8 PF13181.1 GAP82799.1 - 3.9e-06 26.2 0.6 0.29 10.9 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat NB-ARC PF00931.17 GAP82799.1 - 5.7e-06 25.3 0.0 6.4e-05 21.9 0.0 2.3 1 1 0 1 1 1 1 NB-ARC domain TPR_6 PF13174.1 GAP82799.1 - 1.3e-05 25.3 4.8 6.9 7.3 0.1 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAP82799.1 - 2.3e-05 24.2 3.3 5.6 7.4 0.0 5.9 5 1 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 GAP82799.1 - 7.4e-05 22.8 6.7 0.023 14.8 0.1 4.3 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 GAP82799.1 - 0.0077 16.1 0.2 20 5.4 0.0 4.9 6 0 0 6 6 6 0 PPR repeat TPR_4 PF07721.9 GAP82799.1 - 0.008 16.5 19.6 0.3 11.6 0.0 7.2 8 0 0 8 8 5 1 Tetratricopeptide repeat AAA_16 PF13191.1 GAP82799.1 - 0.012 15.6 0.3 0.044 13.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Methyltransf_2 PF00891.13 GAP82801.1 - 3.5e-34 118.0 0.0 4.6e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 GAP82801.1 - 4.9e-05 23.8 0.0 0.00011 22.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAP82801.1 - 0.025 13.9 0.0 0.051 12.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain GST_C PF00043.20 GAP82801.1 - 0.027 14.4 0.0 4.1 7.4 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Methyltransf_31 PF13847.1 GAP82801.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain SNF2_N PF00176.18 GAP82803.1 - 1e-44 152.5 0.0 1.7e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAP82803.1 - 4.7e-13 48.7 0.0 1.2e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 GAP82803.1 - 1.9e-06 27.7 7.4 1.9e-06 27.7 5.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAP82803.1 - 2.9e-06 26.8 10.2 4.3e-06 26.2 5.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAP82803.1 - 4.3e-06 26.2 7.0 1e-05 25.1 4.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAP82803.1 - 1.3e-05 24.9 5.9 3.1e-05 23.7 4.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 GAP82803.1 - 2.1e-05 24.1 6.7 5e-05 22.9 4.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Helicase_C_4 PF13871.1 GAP82803.1 - 0.0076 15.7 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Helicase_C-like zf-RING_UBOX PF13445.1 GAP82803.1 - 0.017 14.8 3.4 0.054 13.2 2.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger SsgA PF04686.7 GAP82803.1 - 0.11 12.1 0.3 0.43 10.2 0.0 2.1 2 0 0 2 2 2 0 Streptomyces sporulation and cell division protein, SsgA zf-C3HC4_4 PF15227.1 GAP82803.1 - 0.39 10.6 7.8 1.1 9.1 5.4 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Peptidase_M20 PF01546.23 GAP82804.1 - 8.9e-25 87.3 0.0 1.4e-24 86.6 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAP82804.1 - 3.4e-18 65.4 0.0 5.5e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 GAP82804.1 - 0.00077 19.2 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 HD_3 PF13023.1 GAP82805.1 - 2e-46 157.7 0.0 2.6e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 HD domain Glyco_hydro_61 PF03443.9 GAP82808.1 - 1.2e-18 67.7 0.3 1.3e-18 67.5 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Astacin PF01400.19 GAP82810.1 - 2.6e-06 26.9 0.3 7.8e-06 25.4 0.2 1.9 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.1 GAP82810.1 - 0.00073 19.5 0.1 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 GAP82810.1 - 0.006 16.6 0.0 0.0095 16.0 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 GAP82810.1 - 0.0062 17.0 0.1 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 GAP82810.1 - 0.013 15.2 2.9 0.032 13.9 1.3 2.2 1 1 1 2 2 2 0 Matrixin Reprolysin_4 PF13583.1 GAP82810.1 - 0.045 13.2 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF3808 PF10300.4 GAP82811.1 - 2.5e-124 415.3 0.0 3.7e-124 414.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_11 PF13414.1 GAP82811.1 - 1.3e-05 24.7 3.0 0.088 12.4 0.4 3.2 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 GAP82811.1 - 0.00087 19.0 2.3 0.23 11.4 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAP82811.1 - 0.0042 17.0 0.5 0.023 14.6 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAP82811.1 - 0.027 14.6 1.1 0.64 10.3 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAP82811.1 - 0.03 15.0 1.0 0.16 12.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAP82811.1 - 0.045 14.2 2.0 42 4.8 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 GAP82811.1 - 0.13 12.7 5.0 12 6.6 0.5 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAP82811.1 - 0.17 11.5 1.3 22 4.8 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAP82811.1 - 3.3 8.5 5.7 3.6 8.4 0.1 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat DSS1_SEM1 PF05160.8 GAP82813.1 - 6.1e-23 80.3 9.8 1e-22 79.6 6.8 1.3 1 0 0 1 1 1 1 DSS1/SEM1 family PGK PF00162.14 GAP82814.1 - 1.5e-152 507.6 0.4 1.7e-152 507.4 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Mpv17_PMP22 PF04117.7 GAP82815.1 - 2.3e-23 81.5 2.1 3.2e-23 81.1 0.1 2.3 3 0 0 3 3 3 1 Mpv17 / PMP22 family DUF2759 PF10958.3 GAP82815.1 - 0.049 13.2 0.1 0.049 13.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) DUF3852 PF12963.2 GAP82815.1 - 0.4 10.7 3.2 0.39 10.7 0.2 2.4 2 2 0 2 2 2 0 Protein of unknown function (DUF3852) LysM PF01476.15 GAP82818.1 - 0.0014 18.4 0.1 0.0048 16.7 0.1 1.9 1 1 0 1 1 1 1 LysM domain LRV_FeS PF05484.6 GAP82818.1 - 0.058 12.9 0.1 0.1 12.1 0.1 1.5 1 1 0 1 1 1 0 LRV protein FeS4 cluster SNF2_N PF00176.18 GAP82819.1 - 1.9e-66 223.9 0.1 2.4e-66 223.5 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 GAP82819.1 - 4.4e-14 52.2 0.0 1.3e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 GAP82819.1 - 1.4e-12 47.2 0.0 4.8e-12 45.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 GAP82819.1 - 1.4e-11 44.0 6.0 3.1e-11 42.9 4.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAP82819.1 - 3.7e-08 33.2 7.7 9.9e-08 31.8 5.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAP82819.1 - 2e-07 31.0 1.7 5.6e-07 29.5 1.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 GAP82819.1 - 2.1e-07 30.5 6.2 4.4e-07 29.5 4.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 GAP82819.1 - 8.4e-07 28.5 5.5 2.1e-06 27.3 3.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAP82819.1 - 1.8e-06 27.7 0.7 3.8e-06 26.6 0.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 GAP82819.1 - 4.9e-06 26.0 7.7 9.6e-06 25.1 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 GAP82819.1 - 6.2e-05 22.4 3.8 0.00013 21.3 2.6 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 GAP82819.1 - 0.01 15.5 4.9 0.034 13.8 3.4 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 GAP82819.1 - 0.011 15.4 0.7 0.7 9.7 0.0 2.7 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 GAP82819.1 - 0.012 15.5 6.2 0.022 14.6 4.3 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-TFIIIC PF12660.2 GAP82819.1 - 0.019 14.8 0.6 0.046 13.6 0.4 1.6 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex zf-RING_4 PF14570.1 GAP82819.1 - 0.062 12.9 6.6 0.13 11.8 4.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain HDA2-3 PF11496.3 GAP82819.1 - 0.15 10.8 0.1 0.89 8.3 0.1 2.0 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 zf-P11 PF03854.9 GAP82819.1 - 0.2 11.1 4.0 3.3 7.2 0.1 2.5 1 1 1 2 2 2 0 P-11 zinc finger CDO_I PF05995.7 GAP82820.1 - 8.8e-39 132.4 0.1 1e-38 132.2 0.1 1.0 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 GAP82820.1 - 1.3e-05 24.6 0.4 1.6e-05 24.3 0.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1637) DUF1774 PF08611.5 GAP82821.1 - 2.3e-31 107.8 3.0 2.3e-31 107.8 2.1 2.6 4 0 0 4 4 4 1 Fungal protein of unknown function (DUF1774) Herpes_UL36 PF03586.8 GAP82821.1 - 0.089 11.8 1.3 2.7 7.0 0.0 2.8 3 0 0 3 3 3 0 Herpesvirus UL36 tegument protein Titin_Z PF09042.6 GAP82821.1 - 0.41 10.2 2.0 0.7 9.5 1.4 1.3 1 0 0 1 1 1 0 Titin Z DUF4231 PF14015.1 GAP82821.1 - 5.1 7.1 7.8 4.8 7.1 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Acyl-CoA_dh_M PF02770.14 GAP82822.1 - 0.024 14.1 0.1 0.071 12.6 0.0 1.8 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, middle domain ACPS PF01648.15 GAP82823.1 - 1.3e-10 41.0 0.0 3.2e-09 36.6 0.0 2.3 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Chorion_2 PF03964.10 GAP82823.1 - 0.039 14.4 1.0 0.039 14.4 0.7 1.8 2 0 0 2 2 2 0 Chorion family 2 Ribosomal_60s PF00428.14 GAP82823.1 - 0.4 11.1 5.3 0.32 11.4 0.7 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Peptidase_M20 PF01546.23 GAP82824.1 - 2.1e-18 66.4 1.7 3.7e-18 65.7 1.2 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAP82824.1 - 2.7e-18 65.7 0.0 4.7e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 GAP82824.1 - 0.0094 15.7 0.8 0.015 15.0 0.6 1.3 1 0 0 1 1 1 1 Peptidase family M28 Ank_2 PF12796.2 GAP82825.1 - 3.5e-36 123.4 15.7 8.3e-14 51.6 0.1 9.3 6 3 4 10 10 10 8 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAP82825.1 - 1.7e-28 98.4 17.3 2e-07 31.3 0.1 12.1 10 2 2 12 12 12 5 Ankyrin repeats (many copies) Ank PF00023.25 GAP82825.1 - 3.2e-28 96.1 13.2 4.9e-06 26.0 0.1 11.7 12 0 0 12 12 12 7 Ankyrin repeat Ank_5 PF13857.1 GAP82825.1 - 1.6e-22 79.0 9.3 1.3e-08 34.8 0.1 10.4 7 3 3 10 10 10 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP82825.1 - 5e-22 75.7 11.1 0.0077 16.3 0.0 13.2 13 0 0 13 13 13 3 Ankyrin repeat Thioredoxin PF00085.15 GAP82825.1 - 1.8e-18 66.1 0.0 4.2e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin NACHT PF05729.7 GAP82825.1 - 2.5e-10 40.2 0.0 8.1e-10 38.6 0.0 1.9 1 0 0 1 1 1 1 NACHT domain Thioredoxin_8 PF13905.1 GAP82825.1 - 0.00045 20.2 0.0 0.0031 17.6 0.0 2.6 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 GAP82825.1 - 0.0096 15.6 0.1 0.18 11.4 0.0 2.7 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.1 GAP82825.1 - 0.013 15.5 0.1 0.05 13.6 0.1 2.0 1 0 0 1 1 1 0 Thioredoxin-like DUF2075 PF09848.4 GAP82825.1 - 0.067 12.1 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Redoxin PF08534.5 GAP82825.1 - 0.13 11.8 0.0 0.6 9.6 0.0 2.1 2 0 0 2 2 2 0 Redoxin Ank_2 PF12796.2 GAP82826.1 - 7.5e-15 55.0 0.3 6.2e-08 32.8 0.0 1.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAP82826.1 - 1.8e-05 24.2 0.0 0.078 12.8 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 GAP82826.1 - 7.7e-05 22.8 0.0 0.46 10.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP82826.1 - 0.00033 20.6 0.0 0.76 10.1 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 GAP82826.1 - 0.039 14.4 0.0 0.37 11.3 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) cobW PF02492.14 GAP82827.1 - 8.3e-47 158.9 7.6 8.1e-35 119.8 0.6 2.1 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 GAP82827.1 - 5e-21 74.2 0.1 3.1e-15 55.6 0.0 3.1 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain CDC45 PF02724.9 GAP82827.1 - 1.8e-05 23.0 1.3 2.2e-05 22.7 0.9 1.1 1 0 0 1 1 1 1 CDC45-like protein GTP_EFTU PF00009.22 GAP82827.1 - 0.0043 16.5 0.1 0.66 9.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SDA1 PF05285.7 GAP82827.1 - 0.0075 15.5 9.5 0.013 14.8 6.6 1.4 1 0 0 1 1 1 1 SDA1 ArgK PF03308.11 GAP82827.1 - 0.0079 15.0 0.4 0.24 10.1 0.0 2.3 2 0 0 2 2 2 1 ArgK protein DUF615 PF04751.9 GAP82827.1 - 0.03 13.9 0.1 0.059 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF615) AAA_18 PF13238.1 GAP82827.1 - 0.036 14.3 2.8 0.13 12.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain TFIIA PF03153.8 GAP82827.1 - 0.038 13.9 7.1 0.047 13.5 4.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 GAP82827.1 - 0.04 11.8 11.0 0.055 11.3 7.7 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 GAP82827.1 - 0.051 12.8 6.2 0.079 12.2 4.3 1.3 1 0 0 1 1 1 0 NOA36 protein BUD22 PF09073.5 GAP82827.1 - 0.053 12.5 8.9 0.085 11.9 6.2 1.2 1 0 0 1 1 1 0 BUD22 UPF0079 PF02367.12 GAP82827.1 - 0.077 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 GAP82827.1 - 0.089 12.4 0.1 0.47 10.1 0.0 2.1 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 GAP82827.1 - 0.095 12.2 0.1 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cwf_Cwc_15 PF04889.7 GAP82827.1 - 1.2 8.8 10.2 2 8.0 7.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-T PF15511.1 GAP82827.1 - 1.2 8.3 7.5 0.15 11.2 1.9 1.7 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T DUF2457 PF10446.4 GAP82827.1 - 1.6 7.3 25.9 2.5 6.7 18.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NARP1 PF12569.3 GAP82829.1 - 5.4e-193 642.4 16.9 2e-191 637.3 6.3 2.4 2 1 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 GAP82829.1 - 4.7e-21 74.2 35.1 2e-06 27.3 0.2 7.8 9 0 0 9 9 8 6 TPR repeat TPR_19 PF14559.1 GAP82829.1 - 1.4e-18 66.9 33.6 3.6e-05 24.0 1.6 7.6 6 2 2 8 8 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 GAP82829.1 - 1.6e-18 65.4 22.4 0.00058 20.2 0.0 10.4 6 3 4 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.1 GAP82829.1 - 5.2e-17 62.0 40.6 4.2e-06 27.2 2.9 8.5 8 2 0 9 9 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 GAP82829.1 - 8.8e-12 43.9 45.1 5.9e-05 22.6 0.1 10.8 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_9 PF13371.1 GAP82829.1 - 1.1e-11 44.3 13.0 0.00011 21.9 0.1 6.6 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAP82829.1 - 5.1e-09 35.9 31.9 0.0027 17.5 0.1 7.7 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 GAP82829.1 - 5.9e-09 35.1 31.7 4.9e-06 25.9 0.2 8.7 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAP82829.1 - 1.7e-08 33.6 8.3 0.0063 16.2 0.0 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat Apc3 PF12895.2 GAP82829.1 - 2.6e-08 33.8 18.0 0.00091 19.3 1.5 5.7 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 GAP82829.1 - 9.4e-08 31.6 10.5 2.8 8.3 0.0 8.5 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_15 PF13429.1 GAP82829.1 - 1.3e-05 24.3 19.9 0.0024 16.9 2.6 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAP82829.1 - 0.00027 20.5 14.8 1.3 8.9 0.0 7.1 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_4 PF07721.9 GAP82829.1 - 0.0053 17.0 7.9 0.25 11.8 0.7 4.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAP82829.1 - 0.015 15.1 10.7 13 5.8 0.4 6.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAP82829.1 - 0.032 14.6 30.4 0.61 10.6 0.1 9.2 11 0 0 11 11 10 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 GAP82829.1 - 9.9 6.1 20.6 0.87 9.5 0.1 5.6 7 0 0 7 7 5 0 Fis1 C-terminal tetratricopeptide repeat Cid2 PF09774.4 GAP82830.1 - 5e-45 153.2 0.0 6.8e-45 152.8 0.0 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 RecX PF02631.11 GAP82831.1 - 0.073 13.2 0.0 0.086 13.0 0.0 1.1 1 0 0 1 1 1 0 RecX family AAA PF00004.24 GAP82832.1 - 8.6e-40 135.9 0.0 1.8e-39 134.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAP82832.1 - 0.00013 21.6 1.1 0.00079 19.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAP82832.1 - 0.00014 21.9 1.0 0.012 15.5 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 GAP82832.1 - 0.00026 20.1 0.0 0.00065 18.8 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 GAP82832.1 - 0.00096 19.3 2.6 0.019 15.1 0.0 3.2 3 1 1 4 4 3 1 AAA domain AAA_2 PF07724.9 GAP82832.1 - 0.0011 18.9 0.5 0.009 15.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 GAP82832.1 - 0.0046 16.2 0.3 0.045 12.9 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 GAP82832.1 - 0.0069 15.5 0.0 0.017 14.2 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 GAP82832.1 - 0.0079 15.1 0.0 0.017 14.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 GAP82832.1 - 0.0099 15.7 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAP82832.1 - 0.017 14.8 0.4 0.044 13.5 0.3 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 GAP82832.1 - 0.023 14.1 0.1 0.047 13.0 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 GAP82832.1 - 0.031 13.6 1.3 0.32 10.3 0.1 2.4 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 GAP82832.1 - 0.042 14.6 1.8 0.092 13.5 0.1 2.4 2 2 0 2 2 2 0 AAA domain AAA_24 PF13479.1 GAP82832.1 - 0.05 13.1 0.1 0.14 11.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 GAP82832.1 - 0.14 11.7 1.7 0.52 9.8 0.0 2.4 2 2 0 2 2 2 0 AAA domain NAM-associated PF14303.1 GAP82832.1 - 7.6 6.8 9.3 19 5.5 6.5 1.6 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Hydrophobin_2 PF06766.6 GAP82833.1 - 2.4e-26 91.1 8.7 3e-26 90.8 6.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin p450 PF00067.17 GAP82834.1 - 5.3e-44 150.4 0.0 8.4e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Aldedh PF00171.17 GAP82836.1 - 1.2e-156 521.7 0.0 1.3e-156 521.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family UCH PF00443.24 GAP82837.1 - 5.3e-41 140.4 0.0 7.9e-35 120.2 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAP82837.1 - 1.9e-11 43.9 3.6 9.5e-11 41.6 0.4 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Dscam_C PF12355.3 GAP82837.1 - 0.014 15.6 3.2 0.53 10.5 2.5 2.8 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal SSFA2_C PF14723.1 GAP82837.1 - 6.8 6.3 7.5 0.54 9.9 0.9 2.1 2 1 1 3 3 3 0 Sperm-specific antigen 2 C-terminus HAD PF12710.2 GAP82838.1 - 4e-12 46.6 0.0 5.5e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 GAP82838.1 - 0.00029 21.1 0.0 0.00073 19.8 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 GAP82838.1 - 0.021 13.9 0.1 0.36 9.9 0.0 2.2 2 0 0 2 2 2 0 Putative Phosphatase Hydrolase PF00702.21 GAP82838.1 - 0.033 14.6 0.3 0.25 11.7 0.1 2.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 GAP82838.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.5 1 1 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) MFS_1 PF07690.11 GAP82839.1 - 1.4e-23 83.2 54.5 4.2e-13 48.7 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAP82839.1 - 0.00019 19.9 26.3 0.0084 14.5 6.4 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein FMN_dh PF01070.13 GAP82840.1 - 1.3e-47 162.4 1.4 1.4e-47 162.3 1.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 GAP82840.1 - 1.3e-08 34.2 0.1 1.6e-08 33.8 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 GAP82840.1 - 9.1e-06 24.7 0.2 1.1e-05 24.5 0.1 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 GAP82840.1 - 0.00076 18.8 0.0 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.10 GAP82840.1 - 0.033 13.3 0.7 0.037 13.1 0.5 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase DHO_dh PF01180.16 GAP82840.1 - 0.053 12.4 0.0 0.11 11.3 0.0 1.5 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Ribul_P_3_epim PF00834.14 GAP82840.1 - 0.14 11.2 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family PI-PLC-X PF00388.14 GAP82841.1 - 8.8e-48 161.4 0.0 1.4e-47 160.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 GAP82841.1 - 8e-32 109.6 0.0 1.4e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain adh_short PF00106.20 GAP82841.1 - 2.6e-28 99.0 3.3 4.7e-28 98.1 2.3 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP82841.1 - 6.2e-14 52.0 0.7 1.2e-13 51.1 0.5 1.4 1 0 0 1 1 1 1 KR domain C2 PF00168.25 GAP82841.1 - 0.09 12.6 1.7 1.2 9.0 1.2 2.4 1 1 0 1 1 1 0 C2 domain tRNA-synt_2 PF00152.15 GAP82842.1 - 5.5e-69 232.4 0.0 7e-69 232.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 GAP82842.1 - 0.065 13.0 0.0 0.2 11.5 0.0 1.9 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain BLOC1_2 PF10046.4 GAP82842.1 - 0.15 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3176 PF11374.3 GAP82843.1 - 6.4e-29 100.0 2.0 1.7e-28 98.7 1.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF726 PF05277.7 GAP82844.1 - 2.4e-16 59.5 0.0 2.8e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF726) BCS1_N PF08740.6 GAP82845.1 - 3.8e-42 144.0 0.1 5.5e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 GAP82845.1 - 2.8e-18 66.3 0.0 4.3e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 GAP82845.1 - 8.6e-06 26.5 0.0 3.3e-05 24.7 0.0 2.1 3 0 0 3 3 1 1 AAA domain AAA_25 PF13481.1 GAP82845.1 - 0.00011 21.7 0.0 0.00027 20.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAP82845.1 - 0.00091 19.2 0.1 0.0038 17.2 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 GAP82845.1 - 0.002 18.0 0.0 0.0045 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 GAP82845.1 - 0.002 18.1 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 GAP82845.1 - 0.0025 16.7 0.0 0.0042 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 GAP82845.1 - 0.0027 17.8 0.0 0.0055 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 GAP82845.1 - 0.0046 16.6 0.0 0.0091 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 GAP82845.1 - 0.0046 16.0 0.0 0.0095 15.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 GAP82845.1 - 0.0057 16.1 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 GAP82845.1 - 0.0075 16.5 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter PPV_E1_C PF00519.12 GAP82845.1 - 0.015 13.9 0.0 0.022 13.3 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase Zeta_toxin PF06414.7 GAP82845.1 - 0.021 13.9 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 GAP82845.1 - 0.024 14.7 0.0 0.045 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 GAP82845.1 - 0.053 13.8 0.0 0.097 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 GAP82845.1 - 0.07 13.0 0.1 0.21 11.5 0.0 1.9 2 0 0 2 2 1 0 50S ribosome-binding GTPase DUF258 PF03193.11 GAP82845.1 - 0.073 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 GAP82845.1 - 0.087 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase KaiC PF06745.8 GAP82845.1 - 0.091 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 KaiC Miro PF08477.8 GAP82845.1 - 0.13 12.7 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein ATP_bind_1 PF03029.12 GAP82845.1 - 0.15 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 GAP82845.1 - 0.17 11.4 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 GAP82845.1 - 0.2 11.9 0.0 0.31 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain GMC_oxred_N PF00732.14 GAP82846.1 - 6.8e-57 192.8 0.0 9.1e-57 192.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAP82846.1 - 1.5e-33 116.0 0.0 3.4e-33 114.9 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAP82846.1 - 4.3e-07 29.1 2.5 0.00055 18.9 0.1 2.6 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAP82846.1 - 6.6e-07 28.5 2.9 2.5e-06 26.6 2.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAP82846.1 - 5.6e-05 23.0 0.1 0.00015 21.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAP82846.1 - 0.00018 20.5 0.7 0.00027 20.0 0.5 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 GAP82846.1 - 0.00057 19.8 0.0 0.0058 16.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAP82846.1 - 0.00098 18.2 0.1 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 GAP82846.1 - 0.016 13.7 0.1 0.027 12.9 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 GAP82846.1 - 0.045 12.3 0.2 0.066 11.8 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 GAP82846.1 - 0.068 13.2 0.1 3.3 7.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAP82846.1 - 0.088 13.2 0.0 0.52 10.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAP82846.1 - 0.1 11.6 0.3 0.16 11.0 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 GAP82846.1 - 0.12 12.1 0.0 0.37 10.5 0.0 1.9 1 0 0 1 1 1 0 FAD-NAD(P)-binding UbiA PF01040.13 GAP82847.1 - 1.2e-06 27.9 1.3 1.9e-06 27.3 0.9 1.4 1 0 0 1 1 1 1 UbiA prenyltransferase family HET PF06985.6 GAP82849.1 - 3e-29 101.9 0.0 4e-28 98.3 0.0 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WAPL PF07814.8 GAP82849.1 - 0.15 10.7 0.1 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin adh_short PF00106.20 GAP82850.1 - 9.6e-08 32.1 0.1 1.8e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.5 GAP82850.1 - 0.0001 21.5 0.0 0.00051 19.2 0.0 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short_C2 PF13561.1 GAP82850.1 - 0.069 12.9 0.2 0.091 12.5 0.1 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase MFS_1 PF07690.11 GAP82852.1 - 4.5e-32 111.1 32.2 5.4e-24 84.5 10.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP82852.1 - 2.9e-12 45.9 3.6 2.9e-12 45.9 2.5 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 GAP82852.1 - 0.00026 19.5 5.6 0.00026 19.5 3.9 3.0 2 1 1 3 3 3 1 MFS/sugar transport protein MFS_3 PF05977.8 GAP82852.1 - 0.047 11.8 11.3 0.1 10.7 1.2 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Pro_dh PF01619.13 GAP82853.1 - 3.2e-07 29.6 1.7 1.4e-05 24.2 1.2 2.0 1 1 0 1 1 1 1 Proline dehydrogenase DUF3740 PF12548.3 GAP82853.1 - 0.075 13.3 0.7 0.086 13.1 0.5 1.1 1 0 0 1 1 1 0 Sulfatase protein NUC153 PF08159.7 GAP82854.1 - 9.1e-15 53.9 13.4 7e-14 51.1 0.8 3.4 3 0 0 3 3 3 2 NUC153 domain Peptidase_A21 PF03566.8 GAP82854.1 - 0.095 10.7 1.1 0.16 10.0 0.8 1.4 1 0 0 1 1 1 0 Peptidase family A21 PLDc_2 PF13091.1 GAP82855.1 - 2.4e-14 53.1 0.9 5.9e-06 26.0 0.0 4.1 4 1 0 4 4 4 3 PLD-like domain PLDc PF00614.17 GAP82855.1 - 3.2e-10 39.4 3.3 0.00015 21.4 0.3 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Thioredoxin PF00085.15 GAP82856.1 - 1.3e-42 143.6 0.0 3.6e-25 87.6 0.0 3.7 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 GAP82856.1 - 1e-09 38.4 0.0 0.0097 15.7 0.0 4.7 4 1 0 5 5 5 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 GAP82856.1 - 4.4e-08 33.1 0.8 0.0015 18.5 0.0 3.9 4 0 0 4 4 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 GAP82856.1 - 1.3e-07 31.7 3.1 0.0011 19.1 0.1 4.5 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 GAP82856.1 - 1.9e-05 24.5 0.5 0.00024 21.0 0.1 2.6 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 GAP82856.1 - 0.00025 20.7 0.5 0.2 11.3 0.0 3.8 4 0 0 4 4 4 1 AhpC/TSA family Thioredoxin_3 PF13192.1 GAP82856.1 - 0.0027 17.4 0.0 0.098 12.4 0.0 2.9 3 0 0 3 3 3 1 Thioredoxin domain 7TM_GPCR_Srh PF10318.4 GAP82856.1 - 0.0028 16.4 0.1 0.005 15.6 0.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh HyaE PF07449.6 GAP82856.1 - 0.036 13.9 0.0 22 5.0 0.0 3.1 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE UBN_AB PF14075.1 GAP82856.1 - 0.13 11.9 0.1 0.13 11.9 0.1 1.5 2 0 0 2 2 1 0 Ubinuclein conserved middle domain TraF PF13728.1 GAP82856.1 - 0.2 11.1 2.5 2.1 7.7 0.0 3.0 3 1 1 4 4 4 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.1 GAP82856.1 - 3 7.8 10.8 0.099 12.6 0.4 3.1 4 0 0 4 4 4 0 Thioredoxin Tyr-DNA_phospho PF06087.7 GAP82857.1 - 1.8e-124 415.7 0.0 2.1e-124 415.5 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Mito_fiss_reg PF05308.6 GAP82857.1 - 0.63 9.3 8.1 1.2 8.4 5.6 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 GAP82857.1 - 7.3 5.7 10.2 13 4.9 7.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ACBP PF00887.14 GAP82859.1 - 3.6e-18 64.9 0.3 4.5e-18 64.6 0.2 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Pyr_redox_2 PF07992.9 GAP82860.1 - 3.8e-16 59.5 4.2 6.7e-16 58.7 1.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAP82860.1 - 8.8e-08 32.4 0.6 3.2e-05 24.2 0.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP82860.1 - 0.00026 21.1 1.9 0.0026 17.8 0.5 2.5 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAP82860.1 - 0.23 10.3 1.6 6.2 5.6 0.3 3.0 3 1 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) EF-hand_4 PF12763.2 GAP82861.1 - 7.6e-48 160.5 0.0 1.4e-47 159.7 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand End3 PF12761.2 GAP82861.1 - 8.2e-45 152.8 0.2 1.2e-44 152.2 0.1 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_8 PF13833.1 GAP82861.1 - 2.1e-06 27.2 0.1 5.6e-06 25.8 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 GAP82861.1 - 2.3e-06 26.4 0.2 2.3e-06 26.4 0.2 2.5 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 GAP82861.1 - 9.3e-05 22.4 0.0 0.00027 21.0 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 GAP82861.1 - 0.0083 15.4 3.6 0.013 14.8 0.1 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 GAP82861.1 - 0.015 15.1 0.1 0.015 15.1 0.1 2.5 3 0 0 3 3 3 0 EF-hand domain COG2 PF06148.6 GAP82861.1 - 0.026 14.3 0.5 0.17 11.7 0.1 2.4 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_MLP1_2 PF07926.7 GAP82861.1 - 0.083 12.6 1.1 8.1 6.1 0.1 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.15 GAP82861.1 - 4 7.2 6.1 3.9 7.2 0.1 2.7 3 0 0 3 3 3 0 Prefoldin subunit GFO_IDH_MocA PF01408.17 GAP82862.1 - 4.7e-17 62.6 0.0 1.3e-16 61.1 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 GAP82862.1 - 0.091 13.0 0.1 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain HET PF06985.6 GAP82865.1 - 4.4e-18 65.7 0.0 1.1e-17 64.5 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Flavodoxin_2 PF02525.12 GAP82866.1 - 1.7e-55 187.6 0.0 2e-55 187.4 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 GAP82866.1 - 3e-14 52.7 0.0 5.3e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.2 GAP82866.1 - 0.0068 15.7 0.2 0.016 14.5 0.1 1.6 1 0 0 1 1 1 1 Flavodoxin H_lectin PF09458.5 GAP82867.1 - 2.2e-18 65.6 0.6 3.7e-18 64.9 0.4 1.4 1 0 0 1 1 1 1 H-type lectin domain Lamprin PF06403.6 GAP82867.1 - 0.036 13.8 4.8 0.054 13.2 3.3 1.2 1 0 0 1 1 1 0 Lamprin HET PF06985.6 GAP82871.1 - 2.1e-34 118.6 0.0 4e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA_19 PF13245.1 GAP82873.1 - 0.027 14.2 0.0 0.073 12.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Methyltransf_11 PF08241.7 GAP82874.1 - 5.2e-10 39.6 0.0 1.1e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP82874.1 - 2.1e-07 31.4 0.0 4.4e-07 30.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP82874.1 - 1.9e-05 24.4 0.0 2.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP82874.1 - 3.3e-05 24.1 0.0 5.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP82874.1 - 0.0025 17.8 0.2 0.0042 17.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP82874.1 - 0.011 16.2 0.0 0.022 15.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Dynamin_N PF00350.18 GAP82875.1 - 1.8e-30 105.9 0.1 3.7e-30 104.9 0.1 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 GAP82875.1 - 6e-13 48.2 0.0 8.5e-12 44.4 0.0 2.2 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 GAP82875.1 - 7.1e-05 22.7 0.0 0.00043 20.2 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.1 GAP82875.1 - 0.00048 20.1 0.0 0.034 14.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Nucleoporin_FG PF13634.1 GAP82875.1 - 0.0017 18.5 89.9 0.3 11.3 26.3 3.5 1 1 2 3 3 3 2 Nucleoporin FG repeat region Miro PF08477.8 GAP82875.1 - 0.016 15.6 0.0 0.038 14.4 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 GAP82875.1 - 0.042 13.3 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 GAP82875.1 - 0.065 12.5 0.0 6.6 5.9 0.0 2.7 2 0 0 2 2 2 0 Ferrous iron transport protein B Methyltransf_2 PF00891.13 GAP82876.1 - 3e-27 95.3 0.0 4.9e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Esterase_phd PF10503.4 GAP82876.1 - 6.1e-24 84.4 1.8 1.1e-23 83.6 1.2 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 GAP82876.1 - 4.5e-07 29.7 0.3 1.1e-06 28.4 0.2 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAP82876.1 - 3.2e-06 26.5 1.5 1.2e-05 24.6 0.8 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.23 GAP82876.1 - 0.047 12.3 0.0 0.078 11.6 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Methyltransf_18 PF12847.2 GAP82878.1 - 7.8e-11 42.5 0.1 1.1e-10 42.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP82878.1 - 9.5e-09 35.6 0.0 1.7e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP82878.1 - 4.3e-08 33.5 0.0 7e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP82878.1 - 1.8e-07 30.8 0.0 2.8e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP82878.1 - 3.5e-06 27.3 0.1 7.8e-06 26.1 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 GAP82878.1 - 4.2e-05 22.9 0.1 6.6e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 GAP82878.1 - 0.00031 20.5 0.0 0.0005 19.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP82878.1 - 0.0021 17.1 0.0 0.003 16.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 GAP82878.1 - 0.0039 16.8 0.0 0.0063 16.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 GAP82878.1 - 0.0065 15.6 0.0 0.0096 15.0 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB DREV PF05219.7 GAP82878.1 - 0.016 14.0 0.0 0.39 9.5 0.0 2.0 2 0 0 2 2 2 0 DREV methyltransferase PCMT PF01135.14 GAP82878.1 - 0.022 14.3 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 GAP82878.1 - 0.025 14.6 5.1 0.066 13.2 3.5 1.8 1 1 0 1 1 1 0 Methyltransferase domain FmrO PF07091.6 GAP82878.1 - 0.033 13.1 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_2 PF00891.13 GAP82878.1 - 0.048 12.8 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_7 PF03492.10 GAP82878.1 - 0.06 12.1 0.0 0.089 11.5 0.0 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase FtsJ PF01728.14 GAP82878.1 - 0.069 13.1 0.0 0.087 12.8 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Cytotoxic PF09000.5 GAP82878.1 - 0.11 12.4 0.0 21 5.1 0.0 3.0 3 0 0 3 3 3 0 Cytotoxic RrnaAD PF00398.15 GAP82878.1 - 0.2 10.6 0.0 0.27 10.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase SR-25 PF10500.4 GAP82879.1 - 0.27 10.6 9.6 0.45 9.9 6.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein YchF-GTPase_C PF06071.8 GAP82880.1 - 1.5e-33 114.4 0.2 3.7e-33 113.1 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 GAP82880.1 - 1.1e-12 47.8 0.0 3.9e-12 46.1 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAP82880.1 - 0.00083 18.6 0.0 0.0019 17.5 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 GAP82880.1 - 0.0019 17.9 0.1 0.0047 16.7 0.0 1.7 1 0 0 1 1 1 1 TGS domain MobB PF03205.9 GAP82880.1 - 0.0074 15.9 0.7 2.5 7.7 0.1 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 GAP82880.1 - 0.031 14.5 0.5 6.6 7.0 0.6 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 GAP82880.1 - 0.039 14.2 2.2 0.26 11.5 1.5 2.0 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 GAP82880.1 - 0.093 12.6 0.0 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain SecA_PP_bind PF01043.15 GAP82880.1 - 0.17 12.2 0.8 1.2 9.5 0.1 2.4 2 1 0 2 2 2 0 SecA preprotein cross-linking domain Peptidase_C97 PF05903.9 GAP82881.1 - 2e-31 108.7 0.0 2.7e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 GAP82881.1 - 0.00086 19.2 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase DUF778 PF05608.7 GAP82881.1 - 0.063 13.2 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF778) Med10 PF09748.4 GAP82882.1 - 0.0039 17.0 0.1 0.0043 16.8 0.1 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex LXG PF04740.7 GAP82882.1 - 0.11 12.3 0.1 0.11 12.2 0.1 1.0 1 0 0 1 1 1 0 LXG domain of WXG superfamily Ribosomal_S11 PF00411.14 GAP82883.1 - 2.5e-13 50.1 0.0 4.4e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 DUF4160 PF13711.1 GAP82883.1 - 0.004 16.9 0.4 0.0088 15.8 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4160) Tim44 PF04280.10 GAP82884.1 - 1.2e-33 116.1 0.0 3.6e-33 114.6 0.0 1.8 2 0 0 2 2 2 1 Tim44-like domain Zip PF02535.17 GAP82884.1 - 2.8 6.8 3.8 4.2 6.2 2.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1768 PF08719.6 GAP82885.1 - 5.6e-47 159.4 0.0 2e-46 157.5 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1768) Spc97_Spc98 PF04130.8 GAP82890.1 - 9.6e-67 225.5 0.0 1.2e-66 225.1 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Senescence PF06911.7 GAP82891.1 - 2.4e-47 160.9 2.3 4e-47 160.2 1.6 1.4 1 0 0 1 1 1 1 Senescence-associated protein DUF3910 PF13049.1 GAP82891.1 - 0.088 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3910) Fungal_trans PF04082.13 GAP82892.1 - 2.4e-17 62.6 0.0 4.7e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP82892.1 - 1.5e-07 31.1 9.4 4e-07 29.8 6.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 GAP82892.1 - 9.5 4.3 16.3 14 3.7 11.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S28 PF05577.7 GAP82894.1 - 3.5e-55 187.3 0.0 4.7e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 GAP82894.1 - 0.0073 16.2 0.2 0.029 14.2 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP82894.1 - 0.045 13.4 0.0 0.17 11.6 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.11 GAP82896.1 - 2.3e-06 26.5 25.6 2.3e-06 26.5 17.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 GAP82896.1 - 3.8e-06 26.4 1.7 8.1e-06 25.4 1.2 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 DUF1772 PF08592.6 GAP82896.1 - 0.033 13.9 7.8 0.45 10.2 4.4 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) BSP PF04450.7 GAP82898.1 - 1e-65 221.0 0.0 1.2e-65 220.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 GAP82898.1 - 2.8e-08 33.8 0.2 6.3e-06 26.2 0.0 2.1 1 1 1 2 2 2 2 Peptidase MA superfamily SprT-like PF10263.4 GAP82898.1 - 0.074 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 SprT-like family CLASP_N PF12348.3 GAP82899.1 - 1.1e-133 443.6 0.1 9.8e-88 293.3 0.0 2.5 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 GAP82899.1 - 1.7e-05 24.4 0.3 9.8 6.5 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat Condensin2nSMC PF12422.3 GAP82899.1 - 0.0095 15.6 0.2 0.79 9.4 0.0 2.6 2 0 0 2 2 2 1 Condensin II non structural maintenance of chromosomes subunit HEAT_EZ PF13513.1 GAP82899.1 - 0.015 15.7 0.1 5 7.7 0.0 4.2 4 0 0 4 4 4 0 HEAT-like repeat Adaptin_N PF01602.15 GAP82899.1 - 0.15 10.3 1.3 6.8 4.8 0.0 3.1 4 1 0 5 5 5 0 Adaptin N terminal region Acetyltransf_1 PF00583.19 GAP82900.1 - 1.2e-08 34.8 0.1 1.8e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAP82900.1 - 4.2e-07 29.6 0.2 1.1e-06 28.2 0.0 1.8 3 0 0 3 3 3 1 FR47-like protein Acetyltransf_10 PF13673.1 GAP82900.1 - 1.2e-05 25.3 0.1 1.6e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAP82900.1 - 0.0031 17.6 0.0 0.0048 17.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAP82900.1 - 0.0054 16.5 0.1 0.017 14.9 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Ribonuclease_T2 PF00445.13 GAP82901.1 - 2.9e-29 102.0 0.0 4.5e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Sec62 PF03839.11 GAP82903.1 - 1.7e-55 187.9 0.4 2.5e-55 187.3 0.3 1.2 1 0 0 1 1 1 1 Translocation protein Sec62 PKI PF02827.11 GAP82903.1 - 0.14 12.2 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor HicB PF05534.7 GAP82903.1 - 0.15 11.6 0.2 1.6 8.3 0.1 2.3 2 0 0 2 2 2 0 HicB family Corona_M PF01635.13 GAP82903.1 - 1.1 8.1 9.7 2.2 7.1 6.7 1.4 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein His_Phos_2 PF00328.17 GAP82905.1 - 8.4e-53 179.9 0.0 1e-52 179.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) TFIIE_alpha PF02002.12 GAP82907.1 - 0.068 12.6 0.1 0.088 12.3 0.0 1.1 1 0 0 1 1 1 0 TFIIE alpha subunit DUF4078 PF13300.1 GAP82907.1 - 0.076 13.1 0.0 0.083 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) UbiA PF01040.13 GAP82908.1 - 1.5e-31 109.5 16.1 2.8e-31 108.6 11.2 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family p450 PF00067.17 GAP82909.1 - 2.8e-43 148.1 0.0 3.6e-43 147.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_4 PF07993.7 GAP82911.1 - 6.9e-31 107.0 0.0 1e-30 106.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 GAP82911.1 - 3.4e-30 104.7 0.0 6.5e-30 103.8 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 GAP82911.1 - 4.3e-12 45.9 0.0 8e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 GAP82911.1 - 4.5e-10 39.6 0.1 1e-09 38.5 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 GAP82911.1 - 0.021 14.7 0.0 0.056 13.3 0.0 1.8 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 GAP82911.1 - 0.03 13.9 0.0 0.075 12.6 0.0 1.7 1 1 0 1 1 1 0 KR domain Voldacs PF03517.8 GAP82912.1 - 1.8e-09 37.5 0.0 2e-09 37.3 0.0 1.0 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Transp_cyt_pur PF02133.10 GAP82913.1 - 8.4e-141 469.4 35.0 9.7e-141 469.2 24.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PARP PF00644.15 GAP82914.1 - 1.4e-49 168.3 1.5 1.2e-48 165.3 0.0 2.6 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 GAP82914.1 - 4.8e-42 142.7 0.4 7.8e-42 142.0 0.3 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 GAP82914.1 - 6.9e-23 80.4 0.7 1.6e-22 79.2 0.5 1.7 1 0 0 1 1 1 1 WGR domain BRCT PF00533.21 GAP82914.1 - 1.1e-12 47.9 0.0 2.1e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 GAP82914.1 - 1.4e-05 24.8 0.0 3.4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain Ndc1_Nup PF09531.5 GAP82914.1 - 9.6 4.4 9.2 23 3.2 6.4 1.6 1 1 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAT1 PF09770.4 GAP82915.1 - 0.032 12.4 39.8 0.033 12.4 27.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spore_coat_CotO PF14153.1 GAP82915.1 - 0.053 12.9 24.2 0.062 12.7 16.8 1.2 1 0 0 1 1 1 0 Spore coat protein CotO GAGA_bind PF06217.7 GAP82915.1 - 0.16 11.8 18.3 0.18 11.7 12.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family TFIIA PF03153.8 GAP82915.1 - 0.22 11.3 30.3 0.25 11.2 21.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.5 GAP82915.1 - 0.28 9.3 48.3 0.32 9.1 33.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MIP-T3 PF10243.4 GAP82915.1 - 0.37 9.2 34.2 0.37 9.2 23.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RCR PF12273.3 GAP82915.1 - 1.2 9.7 27.8 1.5 9.4 19.3 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red MMR1 PF08505.5 GAP82915.1 - 1.4 8.8 20.6 1.6 8.6 14.3 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein RR_TM4-6 PF06459.7 GAP82915.1 - 1.5 8.6 22.0 1.9 8.2 15.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Asp-B-Hydro_N PF05279.6 GAP82915.1 - 1.6 8.5 19.3 1.8 8.3 13.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Hid1 PF12722.2 GAP82915.1 - 1.7 6.2 19.6 1.8 6.1 13.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein eIF3_subunit PF08597.5 GAP82915.1 - 3.5 7.1 22.8 4.3 6.8 15.8 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF4220 PF13968.1 GAP82915.1 - 3.8 6.5 7.2 4.2 6.3 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Neur_chan_memb PF02932.11 GAP82915.1 - 3.8 7.3 15.6 4.1 7.2 10.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4551 PF15087.1 GAP82915.1 - 5.7 5.1 19.3 6.8 4.9 13.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Dicty_REP PF05086.7 GAP82915.1 - 6.1 4.4 16.4 7 4.2 11.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Raftlin PF15250.1 GAP82915.1 - 6.4 5.1 18.7 8.1 4.8 12.9 1.1 1 0 0 1 1 1 0 Raftlin IncA PF04156.9 GAP82915.1 - 7.1 6.1 22.8 9.5 5.7 15.8 1.3 1 0 0 1 1 1 0 IncA protein SprA-related PF12118.3 GAP82915.1 - 8.8 5.5 41.4 12 5.1 28.7 1.2 1 0 0 1 1 1 0 SprA-related family SPT2 PF08243.6 GAP82916.1 - 2.5e-05 24.5 31.4 3.2e-05 24.2 17.3 2.8 2 1 0 2 2 2 1 SPT2 chromatin protein DUF2423 PF10338.4 GAP82916.1 - 0.082 12.8 4.3 0.33 10.9 3.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2423) Ribosomal_60s PF00428.14 GAP82918.1 - 1.2e-28 99.3 9.7 1.4e-28 99.1 6.8 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein RibD_C PF01872.12 GAP82918.1 - 0.078 12.5 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 RibD C-terminal domain Pkinase PF00069.20 GAP82919.1 - 1.4e-44 152.2 0.0 2.1e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP82919.1 - 5.3e-19 68.2 0.0 1e-18 67.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 GAP82919.1 - 0.0054 16.0 0.5 0.06 12.6 0.3 2.1 1 1 0 1 1 1 1 RIO1 family PsaA_PsaB PF00223.14 GAP82919.1 - 0.053 11.6 0.0 0.076 11.0 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein Ribosomal_L21p PF00829.16 GAP82920.1 - 0.0039 17.2 0.0 0.0051 16.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein NUFIP1 PF10453.4 GAP82921.1 - 9e-09 34.7 0.6 2.7e-08 33.1 0.4 1.8 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 GAP82921.1 - 0.44 10.2 7.6 0.89 9.3 5.3 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HrpB7 PF09486.5 GAP82921.1 - 2.1 8.2 5.1 0.26 11.2 0.7 1.5 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Cut8_N PF14482.1 GAP82921.1 - 7.1 6.7 11.7 26 4.8 0.2 4.2 2 2 0 2 2 2 0 Cut8 proteasome-binding domain RNA_pol_Rbc25 PF08292.7 GAP82922.1 - 2.5e-29 101.9 0.5 4.5e-29 101.1 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 GAP82922.1 - 1.8e-16 59.9 0.0 3.3e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DUF106 PF01956.11 GAP82923.1 - 3e-52 176.5 3.2 3.8e-52 176.2 2.2 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 SPC25 PF06703.6 GAP82924.1 - 5.8e-53 178.7 0.0 7.6e-53 178.4 0.0 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Glyco_hydro_3_C PF01915.17 GAP82925.1 - 0.00012 21.6 0.1 0.00013 21.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain DUF1842 PF08896.5 GAP82925.1 - 0.028 14.1 0.0 0.03 14.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1842) MMS19_N PF14500.1 GAP82926.1 - 2.6e-34 118.7 0.6 1.7e-33 116.0 0.1 2.2 1 1 1 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II THF_DHG_CYH PF00763.18 GAP82927.1 - 2.6e-18 66.1 0.0 3.9e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 GAP82927.1 - 1.1e-13 50.5 0.0 1.6e-08 33.7 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SBP_bac_5 PF00496.17 GAP82927.1 - 0.0033 16.2 0.0 0.0045 15.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Ank_2 PF12796.2 GAP82928.1 - 1.3e-48 163.2 0.0 2.6e-17 62.9 0.1 8.5 6 1 1 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 GAP82928.1 - 2.2e-38 128.1 12.1 5.9e-07 28.9 0.0 11.8 12 0 0 12 12 12 5 Ankyrin repeat Ank_3 PF13606.1 GAP82928.1 - 2e-33 111.1 6.2 2.2e-05 24.2 0.0 12.7 15 0 0 15 15 15 7 Ankyrin repeat Ank_5 PF13857.1 GAP82928.1 - 1.5e-30 104.5 1.1 7.8e-05 22.7 0.0 10.1 9 0 0 9 9 9 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAP82928.1 - 2.3e-30 104.4 0.2 4.2e-05 23.9 0.0 9.8 8 1 1 9 9 9 5 Ankyrin repeats (many copies) CENP-C_C PF11699.3 GAP82929.1 - 0.023 14.6 0.0 0.023 14.6 0.0 1.0 1 0 0 1 1 1 0 Mif2/CENP-C like Abhydrolase_5 PF12695.2 GAP82930.1 - 1.8e-13 50.4 0.0 3.1e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 GAP82930.1 - 1.9e-12 46.5 0.0 4e-12 45.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.2 GAP82930.1 - 4.9e-11 42.9 3.4 4.9e-11 42.9 2.3 2.2 1 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 GAP82930.1 - 0.00025 20.5 0.0 0.00042 19.8 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.15 GAP82930.1 - 0.0013 18.1 0.0 0.0042 16.5 0.0 1.8 1 1 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 GAP82930.1 - 0.0015 18.1 0.2 0.17 11.4 0.1 3.0 1 1 1 3 3 3 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAP82930.1 - 0.0015 17.7 0.0 0.0038 16.4 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.7 GAP82930.1 - 0.0017 16.9 0.0 0.95 7.9 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 GAP82930.1 - 0.0028 17.1 0.0 0.0067 15.8 0.0 1.6 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.8 GAP82930.1 - 0.078 12.5 0.0 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S10 PF00450.17 GAP82931.1 - 7.1e-69 232.9 0.0 8.4e-69 232.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase GIDE PF12483.3 GAP82931.1 - 0.0065 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 E3 Ubiquitin ligase Abhydrolase_5 PF12695.2 GAP82931.1 - 0.025 14.3 0.1 0.057 13.1 0.1 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family ADH_N PF08240.7 GAP82932.1 - 1.4e-24 85.9 4.8 2.3e-24 85.2 3.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAP82932.1 - 1e-19 70.3 0.1 1.6e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAP82932.1 - 1.1e-06 29.5 0.0 2e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 GAP82932.1 - 0.018 14.1 0.1 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PolyA_pol PF01743.15 GAP82933.1 - 4.4e-19 68.9 0.0 9.5e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 GAP82933.1 - 0.0011 18.5 0.1 0.0028 17.1 0.0 1.8 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A DUF742 PF05331.6 GAP82933.1 - 0.025 14.1 0.1 0.22 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF742) Glycos_transf_4 PF00953.16 GAP82934.1 - 2.8e-31 108.4 13.5 2.8e-31 108.4 9.4 2.0 2 1 0 2 2 2 1 Glycosyl transferase family 4 Suf PF05843.9 GAP82935.1 - 0.0094 15.7 1.4 0.014 15.1 1.0 1.3 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Med15 PF09606.5 GAP82935.1 - 1.6 6.8 23.8 2 6.5 16.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CDK2AP PF09806.4 GAP82935.1 - 2.5 8.2 12.1 4.6 7.4 8.4 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein PAT1 PF09770.4 GAP82935.1 - 3.5 5.7 20.5 4.5 5.3 14.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 GAP82935.1 - 8.6 6.1 14.8 11 5.8 10.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PHD PF00628.24 GAP82939.1 - 1.2e-07 31.2 9.3 2.4e-07 30.3 6.5 1.5 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 GAP82939.1 - 2.6e-05 24.5 0.0 2.6e-05 24.5 0.0 3.0 3 1 0 3 3 3 1 SET domain GMC_oxred_N PF00732.14 GAP82940.1 - 4.1e-51 173.8 0.1 1e-50 172.5 0.1 1.6 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAP82940.1 - 4.8e-30 104.7 0.0 8.5e-30 103.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Amidase PF01425.16 GAP82941.1 - 4.3e-73 246.6 0.1 7.7e-70 235.9 0.0 2.1 2 0 0 2 2 2 2 Amidase DUF619 PF04768.8 GAP82942.1 - 1.7e-49 167.5 0.0 9e-49 165.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF619) rRNA_methylase PF06962.7 GAP82942.1 - 0.17 11.6 0.0 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Putative rRNA methylase HSP70 PF00012.15 GAP82943.1 - 1.4e-172 574.7 8.7 6.6e-172 572.5 6.0 1.9 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAP82943.1 - 3.8e-12 45.4 0.0 3.3e-10 39.0 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 GAP82943.1 - 0.0022 17.8 0.5 3.8 7.3 0.0 3.2 2 2 0 2 2 2 2 Cell division protein FtsA GTP_EFTU PF00009.22 GAP82944.1 - 6.3e-32 110.5 0.0 2.5e-31 108.5 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 GAP82944.1 - 6.9e-18 64.5 0.0 1.7e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 GAP82944.1 - 1.5e-09 37.8 9.0 9.1e-07 28.9 0.4 3.6 4 0 0 4 4 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAP82944.1 - 3.7e-06 26.8 0.2 1.4e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 GAP82944.1 - 0.00082 19.8 0.4 0.0038 17.7 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein ATP_bind_1 PF03029.12 GAP82944.1 - 0.0038 16.7 0.0 0.0092 15.5 0.0 1.7 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU_D4 PF14578.1 GAP82944.1 - 0.0048 16.5 0.1 0.013 15.1 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Ras PF00071.17 GAP82944.1 - 0.043 13.2 0.0 0.23 10.8 0.0 2.4 1 1 0 1 1 1 0 Ras family Reo_P9 PF06043.6 GAP82944.1 - 0.051 12.6 0.1 0.089 11.8 0.1 1.3 1 0 0 1 1 1 0 Reovirus P9-like family AAA_16 PF13191.1 GAP82944.1 - 0.092 12.7 0.0 0.092 12.7 0.0 2.4 1 1 1 2 2 2 0 AAA ATPase domain TrkA_C PF02080.16 GAP82944.1 - 0.094 12.3 0.8 4.9 6.8 0.0 2.5 2 0 0 2 2 2 0 TrkA-C domain AAA_22 PF13401.1 GAP82944.1 - 0.1 12.7 0.0 0.49 10.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain CytochromB561_N PF09786.4 GAP82944.1 - 1.1 7.6 3.7 2.5 6.4 2.6 1.5 1 0 0 1 1 1 0 Cytochrome B561, N terminal HET PF06985.6 GAP82945.1 - 2.1e-23 82.9 0.0 4.2e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MMS1_N PF10433.4 GAP82946.1 - 1.8e-76 257.2 0.0 3.8e-76 256.2 0.0 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term APH PF01636.18 GAP82947.1 - 9.2e-11 41.9 0.0 1.7e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RabGAP-TBC PF00566.13 GAP82948.1 - 7.2e-22 77.9 0.0 9.1e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Vps52 PF04129.7 GAP82949.1 - 7.8e-121 404.0 0.0 1.1e-120 403.6 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 GAP82949.1 - 1.1e-05 23.8 1.0 2.8e-05 22.5 0.7 1.5 1 1 0 1 1 1 1 Exocyst complex component Sec3 Mer2 PF09074.5 GAP82949.1 - 0.013 15.4 1.4 0.054 13.4 0.1 2.5 3 0 0 3 3 3 0 Mer2 DUF1664 PF07889.7 GAP82949.1 - 0.016 14.9 0.3 0.035 13.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) MscS_porin PF12795.2 GAP82949.1 - 0.02 14.2 1.0 0.02 14.2 0.7 1.7 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain eIF-5a PF01287.15 GAP82950.1 - 5e-15 55.1 0.3 7e-15 54.7 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 GAP82950.1 - 1.7e-05 24.3 0.6 3.9e-05 23.2 0.4 1.6 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 GAP82950.1 - 0.00018 21.3 0.2 0.024 14.4 0.0 2.5 3 0 0 3 3 3 2 Elongation factor P (EF-P) KOW-like domain RRN7 PF11781.3 GAP82951.1 - 0.026 14.0 4.4 0.023 14.1 1.9 1.8 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 ubiquitin PF00240.18 GAP82952.1 - 2.8e-34 116.3 0.9 3.9e-34 115.8 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 GAP82952.1 - 6.5e-30 102.4 9.4 1.2e-29 101.6 6.5 1.5 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 GAP82952.1 - 2.6e-19 68.6 0.7 3.7e-19 68.1 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 GAP82952.1 - 1.2e-05 25.4 0.2 4e-05 23.7 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 GAP82952.1 - 0.00028 20.6 0.0 0.0004 20.0 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 GAP82952.1 - 0.015 15.1 0.1 0.039 13.8 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 GAP82952.1 - 0.019 15.1 0.1 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Eaf7 PF07904.8 GAP82953.1 - 1.3e-25 89.2 0.1 1.3e-25 89.2 0.1 2.7 2 1 0 2 2 2 1 Chromatin modification-related protein EAF7 Nop14 PF04147.7 GAP82953.1 - 0.0088 14.0 36.6 0.013 13.4 25.3 1.3 1 0 0 1 1 1 1 Nop14-like family VID27 PF08553.5 GAP82953.1 - 0.017 13.4 17.0 0.023 12.9 11.8 1.4 1 0 0 1 1 1 0 VID27 cytoplasmic protein Paf1 PF03985.8 GAP82953.1 - 0.71 8.5 29.1 1.1 7.9 20.2 1.3 1 0 0 1 1 1 0 Paf1 Spc97_Spc98 PF04130.8 GAP82954.1 - 3.3e-75 253.4 0.0 4.7e-75 252.9 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family DASH_Ask1 PF08655.5 GAP82955.1 - 9.4e-33 111.8 0.1 1.4e-32 111.2 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 YqfQ PF14181.1 GAP82955.1 - 0.081 12.9 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 YqfQ-like protein CLAMP PF14769.1 GAP82956.1 - 0.002 18.2 0.0 0.0028 17.7 0.0 1.2 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 Codanin-1_C PF15296.1 GAP82956.1 - 0.009 15.8 1.2 0.23 11.3 0.2 2.1 1 1 1 2 2 2 2 Codanin-1 C-terminus DUF3484 PF11983.3 GAP82956.1 - 0.12 13.2 0.1 0.29 11.9 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3484) p450 PF00067.17 GAP82957.1 - 6.9e-50 169.9 0.0 1.1e-49 169.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Phage_T7_Capsid PF05396.6 GAP82957.1 - 0.14 12.3 0.0 0.43 10.7 0.0 1.8 2 0 0 2 2 2 0 Phage T7 capsid assembly protein LCM PF04072.9 GAP82959.1 - 3.1e-23 82.3 0.0 6.8e-23 81.1 0.0 1.6 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase Mito_carr PF00153.22 GAP82960.1 - 0.0017 18.0 0.1 1.1 9.0 0.0 2.6 2 1 0 2 2 2 2 Mitochondrial carrier protein AurF PF11583.3 GAP82960.1 - 0.13 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 P-aminobenzoate N-oxygenase AurF TFIID-18kDa PF02269.11 GAP82961.1 - 2.5e-27 94.5 0.9 3.4e-26 90.8 0.1 2.6 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.18 GAP82961.1 - 0.035 14.1 0.3 1.1 9.3 0.1 2.4 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Sporozoite_P67 PF05642.6 GAP82961.1 - 0.076 10.8 0.2 0.078 10.8 0.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3313 PF11769.3 GAP82961.1 - 0.081 12.2 0.3 0.52 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3313) DUF2027 PF09640.5 GAP82961.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2027) NACHT PF05729.7 GAP82962.1 - 1.3e-09 37.9 0.0 2.7e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.15 GAP82962.1 - 1.2e-08 34.2 0.9 8.1e-08 31.5 0.6 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_22 PF13401.1 GAP82962.1 - 1.5e-06 28.3 0.0 4.2e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAP82962.1 - 8.1e-06 25.9 0.5 2.5e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Ank_2 PF12796.2 GAP82962.1 - 0.00018 21.7 0.0 0.0014 18.9 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAP82962.1 - 0.003 17.2 0.1 0.2 11.5 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat KAP_NTPase PF07693.9 GAP82962.1 - 0.0063 15.5 0.1 0.38 9.7 0.0 2.5 3 0 0 3 3 3 1 KAP family P-loop domain Ank_4 PF13637.1 GAP82962.1 - 0.011 16.2 0.1 0.058 13.9 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) AAA_17 PF13207.1 GAP82962.1 - 0.051 14.4 0.0 0.2 12.4 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA PF00004.24 GAP82962.1 - 0.11 12.7 0.0 0.7 10.0 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ank_3 PF13606.1 GAP82962.1 - 0.14 12.5 0.0 4.2 7.8 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat FUN14 PF04930.10 GAP82962.1 - 0.49 10.7 1.7 17 5.7 0.0 2.8 2 1 0 2 2 2 0 FUN14 family DUF239 PF03080.10 GAP82964.1 - 3.1e-31 108.2 4.5 3.5e-31 108.0 3.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF239) BA14K PF07886.6 GAP82964.1 - 7.5 6.3 7.4 8.9 6.0 0.6 2.6 2 0 0 2 2 2 0 BA14K-like protein HET PF06985.6 GAP82965.1 - 4.4e-25 88.4 0.0 6.9e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.20 GAP82966.1 - 1.1e-23 84.0 3.0 1.6e-23 83.4 2.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 GAP82966.1 - 7.5e-11 42.3 0.1 1.4e-10 41.5 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 GAP82966.1 - 1.9e-09 37.6 0.0 4.2e-09 36.5 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP82966.1 - 2.9e-07 30.3 1.1 2.9e-07 30.3 0.7 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 GAP82966.1 - 6e-05 22.5 0.0 0.00013 21.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAP82966.1 - 0.0015 18.2 0.5 0.0015 18.2 0.4 2.0 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 GAP82966.1 - 0.0046 16.2 0.0 0.025 13.8 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family PP2C_2 PF13672.1 GAP82966.1 - 0.032 13.6 0.5 0.082 12.2 0.2 1.5 1 1 0 1 1 1 0 Protein phosphatase 2C adh_short PF00106.20 GAP82967.1 - 1.3e-27 96.8 8.1 1.9e-27 96.1 5.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP82967.1 - 1.2e-20 74.2 0.1 1e-19 71.2 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP82967.1 - 7.2e-12 45.3 3.8 1e-11 44.8 2.7 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 GAP82967.1 - 0.0015 18.1 1.9 0.0025 17.4 1.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 GAP82967.1 - 0.016 15.0 0.5 0.027 14.3 0.3 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 GAP82967.1 - 0.032 13.3 0.1 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 GAP82967.1 - 0.068 12.2 0.1 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glycos_transf_2 PF00535.21 GAP82968.1 - 5.6e-32 110.7 0.0 6.7e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 GAP82968.1 - 1.1e-10 41.7 0.0 1.6e-10 41.1 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 GAP82968.1 - 1.6e-08 33.9 0.0 2.1e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 GAP82968.1 - 0.00014 21.2 0.0 0.00022 20.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Ank_2 PF12796.2 GAP82969.1 - 3.9e-75 248.2 8.0 4.9e-16 58.8 0.0 7.1 3 2 4 8 8 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 GAP82969.1 - 3.1e-60 197.1 13.3 2.4e-06 27.0 0.0 13.9 13 0 0 13 13 13 12 Ankyrin repeat Ank_4 PF13637.1 GAP82969.1 - 7.7e-60 198.2 3.6 5.1e-09 36.4 0.1 10.0 6 3 3 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP82969.1 - 1.7e-48 157.7 4.0 0.0013 18.7 0.0 14.4 14 0 0 14 14 14 10 Ankyrin repeat Ank_5 PF13857.1 GAP82969.1 - 2.2e-48 161.1 15.2 6.4e-06 26.2 0.0 12.7 6 2 6 13 13 13 9 Ankyrin repeats (many copies) HeLo PF14479.1 GAP82969.1 - 1.6e-20 73.7 0.0 1.4e-19 70.7 0.0 2.2 1 1 0 1 1 1 1 Prion-inhibition and propagation NACHT PF05729.7 GAP82969.1 - 6.9e-12 45.3 0.0 1.8e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 GAP82969.1 - 3.2e-06 27.2 0.1 2.2e-05 24.5 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 GAP82969.1 - 0.00011 22.3 0.0 0.00044 20.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 GAP82969.1 - 0.00022 20.2 0.0 0.0008 18.3 0.0 1.8 1 1 0 1 1 1 1 NB-ARC domain AAA PF00004.24 GAP82969.1 - 0.0021 18.2 0.0 0.03 14.4 0.0 2.4 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 GAP82969.1 - 0.006 16.3 0.0 0.022 14.5 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 GAP82969.1 - 0.021 14.7 0.0 0.055 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 GAP82969.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 GAP82969.1 - 0.16 11.6 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase ZZ PF00569.12 GAP82969.1 - 0.18 11.3 6.2 0.46 10.0 4.3 1.6 1 0 0 1 1 1 0 Zinc finger, ZZ type PfkB PF00294.19 GAP82970.1 - 1.2e-14 54.2 0.0 1.7e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HET PF06985.6 GAP82971.1 - 6.5e-32 110.5 0.0 9.7e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Isochorismatase PF00857.15 GAP82972.1 - 6.2e-39 133.6 0.1 7.4e-39 133.4 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family Lipase_GDSL_2 PF13472.1 GAP82972.1 - 0.085 12.9 2.7 1.1 9.3 0.6 2.1 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family MDMPI_N PF11716.3 GAP82972.1 - 0.59 10.5 7.3 0.72 10.2 3.2 2.3 1 1 2 3 3 3 0 Mycothiol maleylpyruvate isomerase N-terminal domain TFR_dimer PF04253.10 GAP82974.1 - 1.9e-24 85.6 0.0 3.1e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 GAP82974.1 - 1.9e-13 50.5 0.0 3.5e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 GAP82974.1 - 2.9e-06 26.8 0.1 6.1e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.10 GAP82974.1 - 0.038 13.2 0.0 0.063 12.5 0.0 1.3 1 0 0 1 1 1 0 Nicastrin Vps35 PF03635.12 GAP82975.1 - 0 1023.0 0.0 0 1022.8 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 HET PF06985.6 GAP82977.1 - 1.4e-24 86.7 0.0 2.4e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fer4_8 PF13183.1 GAP82977.1 - 0.036 14.0 0.2 0.097 12.7 0.1 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain DUF1664 PF07889.7 GAP82978.1 - 4.3e-10 39.4 19.7 0.0036 17.1 1.7 4.3 1 1 3 4 4 4 4 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 GAP82978.1 - 8.3e-09 35.4 39.9 8.6e-07 28.8 16.1 2.8 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.8 GAP82978.1 - 2.3e-08 33.6 34.9 0.21 11.4 0.2 7.6 2 1 5 7 7 7 3 Lipoprotein leucine-zipper Apolipoprotein PF01442.13 GAP82978.1 - 7.5e-07 28.8 12.5 1.7e-05 24.4 2.6 2.0 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Phe_tRNA-synt_N PF02912.13 GAP82978.1 - 2.5e-05 23.9 12.5 0.037 13.7 0.4 5.5 1 1 4 5 5 5 1 Aminoacyl tRNA synthetase class II, N-terminal domain OmpH PF03938.9 GAP82978.1 - 0.00014 21.8 18.5 0.027 14.4 4.1 2.2 1 1 1 2 2 2 2 Outer membrane protein (OmpH-like) DUF3584 PF12128.3 GAP82978.1 - 0.00015 19.2 17.7 0.00087 16.7 12.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3584) Filament PF00038.16 GAP82978.1 - 0.00018 21.0 14.4 0.00028 20.4 8.9 1.8 1 1 0 1 1 1 1 Intermediate filament protein DUF883 PF05957.8 GAP82978.1 - 0.00054 20.3 8.3 0.081 13.3 0.9 3.3 1 1 2 3 3 3 2 Bacterial protein of unknown function (DUF883) DUF2580 PF10824.3 GAP82978.1 - 0.001 19.3 1.8 0.12 12.6 0.1 3.1 1 1 2 3 3 3 1 Protein of unknown function (DUF2580) AAA_13 PF13166.1 GAP82978.1 - 0.0011 17.5 21.3 0.0015 17.0 14.8 1.1 1 0 0 1 1 1 1 AAA domain Myosin_tail_1 PF01576.14 GAP82978.1 - 0.0011 16.7 14.4 0.0014 16.4 10.0 1.1 1 0 0 1 1 1 1 Myosin tail Cortex-I_coil PF09304.5 GAP82978.1 - 0.0015 18.5 4.7 0.0015 18.5 3.2 3.2 1 1 2 3 3 3 1 Cortexillin I, coiled coil SF-assemblin PF06705.6 GAP82978.1 - 0.0019 17.3 22.1 0.059 12.5 5.9 2.5 1 1 1 2 2 2 2 SF-assemblin/beta giardin V-SNARE PF05008.10 GAP82978.1 - 0.0022 18.1 10.7 0.016 15.3 1.3 3.2 1 1 1 3 3 3 2 Vesicle transport v-SNARE protein N-terminus Leu_zip PF15294.1 GAP82978.1 - 0.0028 16.7 11.6 0.19 10.8 0.4 3.1 1 1 2 3 3 3 2 Leucine zipper Prominin PF05478.6 GAP82978.1 - 0.0032 15.0 20.9 0.0057 14.2 14.5 1.3 1 1 0 1 1 1 1 Prominin Fzo_mitofusin PF04799.8 GAP82978.1 - 0.0051 16.2 17.6 0.042 13.2 3.8 3.4 1 1 3 4 4 4 2 fzo-like conserved region ApoO PF09769.4 GAP82978.1 - 0.0066 16.1 5.0 0.22 11.2 1.9 3.1 1 1 1 2 2 2 1 Apolipoprotein O COG2 PF06148.6 GAP82978.1 - 0.0069 16.2 13.2 1.1 9.0 0.2 4.1 1 1 2 3 3 3 2 COG (conserved oligomeric Golgi) complex component, COG2 Mer2 PF09074.5 GAP82978.1 - 0.0094 15.8 21.8 0.062 13.2 5.9 2.6 1 1 1 2 2 2 1 Mer2 DUF4407 PF14362.1 GAP82978.1 - 0.024 13.6 19.8 0.035 13.0 13.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RESP18 PF14948.1 GAP82978.1 - 0.027 14.5 3.8 0.14 12.2 0.1 3.1 1 1 1 3 3 3 0 RESP18 domain DUF3618 PF12277.3 GAP82978.1 - 0.028 14.4 5.3 21 5.2 0.2 5.0 3 1 3 6 6 5 0 Protein of unknown function (DUF3618) AIP3 PF03915.8 GAP82978.1 - 0.029 13.3 21.3 0.23 10.3 13.9 2.0 1 1 1 2 2 2 0 Actin interacting protein 3 APG17 PF04108.7 GAP82978.1 - 0.03 13.1 16.7 0.19 10.4 10.9 2.4 1 1 1 2 2 2 0 Autophagy protein Apg17 Mitofilin PF09731.4 GAP82978.1 - 0.032 12.8 12.8 0.046 12.3 8.8 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Alpha-E PF04168.7 GAP82978.1 - 0.034 13.5 7.0 0.44 9.8 0.2 3.0 1 1 2 3 3 3 0 A predicted alpha-helical domain with a conserved ER motif. ApoLp-III PF07464.6 GAP82978.1 - 0.047 13.7 19.5 0.42 10.6 7.3 2.3 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF1640 PF07798.6 GAP82978.1 - 0.048 13.6 17.3 0.028 14.4 7.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Baculo_p24 PF05073.7 GAP82978.1 - 0.052 13.0 22.1 0.1 12.1 5.1 2.2 1 1 1 2 2 2 0 Baculovirus P24 capsid protein DUF4071 PF13281.1 GAP82978.1 - 0.054 12.3 10.7 0.22 10.3 1.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4071) DUF948 PF06103.6 GAP82978.1 - 0.066 13.0 29.1 0.31 10.9 6.3 3.9 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) YlqD PF11068.3 GAP82978.1 - 0.071 13.1 17.7 8.1 6.4 8.9 3.2 1 1 2 3 3 3 0 YlqD protein Latarcin PF10279.4 GAP82978.1 - 0.081 13.1 7.9 35 4.6 5.5 3.4 1 1 0 1 1 1 0 Latarcin precursor SPX PF03105.14 GAP82978.1 - 0.086 12.6 4.0 0.2 11.3 2.8 1.6 1 1 0 1 1 1 0 SPX domain KfrA_N PF11740.3 GAP82978.1 - 0.11 12.9 6.7 1.9 8.9 0.1 2.8 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term WXG100 PF06013.7 GAP82978.1 - 0.16 11.9 16.4 9.3 6.3 0.1 4.8 1 1 4 5 5 5 0 Proteins of 100 residues with WXG DUF2451 PF10474.4 GAP82978.1 - 0.18 11.5 4.5 0.69 9.6 2.9 2.1 1 1 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) Val_tRNA-synt_C PF10458.4 GAP82978.1 - 0.23 11.5 1.4 19 5.4 0.1 3.6 1 1 4 6 6 4 0 Valyl tRNA synthetase tRNA binding arm DUF3810 PF12725.2 GAP82978.1 - 0.27 10.0 14.3 0.84 8.4 0.4 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3810) YtxH PF12732.2 GAP82978.1 - 0.36 11.2 14.7 8.8e+03 -2.9 10.2 4.1 1 1 0 1 1 0 0 YtxH-like protein DUF2317 PF10079.4 GAP82978.1 - 0.37 9.3 13.4 0.69 8.4 3.9 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF148 PF02520.12 GAP82978.1 - 0.43 10.3 22.6 2.8 7.7 5.0 3.0 1 1 1 2 2 2 0 Domain of unknown function DUF148 DUF1110 PF06533.7 GAP82978.1 - 0.45 10.3 4.0 9.1 6.0 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1110) DUF842 PF05811.8 GAP82978.1 - 0.61 9.5 6.8 1.7 8.1 0.8 2.2 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) DUF1515 PF07439.6 GAP82978.1 - 0.66 9.8 11.9 1.1 9.0 1.5 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) ATP-synt_B PF00430.13 GAP82978.1 - 0.73 9.6 18.3 0.81 9.4 2.0 2.7 1 1 2 3 3 3 0 ATP synthase B/B' CF(0) IncA PF04156.9 GAP82978.1 - 0.75 9.3 9.5 7.3 6.1 6.5 2.5 1 1 1 2 2 2 0 IncA protein CENP-F_leu_zip PF10473.4 GAP82978.1 - 0.87 9.4 10.1 0.21 11.4 2.5 2.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG5 PF10392.4 GAP82978.1 - 0.9 9.5 13.5 8.8 6.3 6.2 3.3 2 1 1 3 3 2 0 Golgi transport complex subunit 5 Allexi_40kDa PF05549.6 GAP82978.1 - 0.91 8.7 15.9 1.3 8.2 2.9 2.8 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF1451 PF07295.6 GAP82978.1 - 0.96 9.2 11.4 2.2 8.0 2.4 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1451) Tht1 PF04163.7 GAP82978.1 - 0.97 7.7 18.9 1.4 7.2 13.1 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein Phage_Mu_Gam PF07352.7 GAP82978.1 - 1 8.8 11.6 9 5.7 0.2 3.7 1 1 4 5 5 5 0 Bacteriophage Mu Gam like protein V_ATPase_I PF01496.14 GAP82978.1 - 1.2 6.9 10.9 21 2.8 7.6 2.1 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.8 GAP82978.1 - 1.2 8.1 12.9 2.3 7.2 1.6 2.2 1 1 1 2 2 2 0 TMPIT-like protein Phage_GPO PF05929.6 GAP82978.1 - 1.2 8.3 16.5 4.1 6.5 5.1 2.4 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF3418 PF11898.3 GAP82978.1 - 1.3 7.3 11.1 3.3 6.0 2.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3418) DUF2450 PF10475.4 GAP82978.1 - 1.4 7.7 12.5 3 6.6 2.6 3.0 1 1 2 3 3 3 0 Protein of unknown function N-terminal domain (DUF2450) Sds3 PF08598.6 GAP82978.1 - 1.5 8.3 10.4 2.6 7.5 0.3 2.4 1 1 1 2 2 2 0 Sds3-like Spectrin PF00435.16 GAP82978.1 - 1.7 8.9 11.9 1.9 8.8 3.4 2.9 1 1 2 3 3 3 0 Spectrin repeat PEP-utilisers_N PF05524.8 GAP82978.1 - 2.4 7.9 7.0 5 6.9 1.0 3.4 2 1 1 3 3 2 0 PEP-utilising enzyme, N-terminal Syntaxin PF00804.20 GAP82978.1 - 2.5 8.3 23.8 1.5e+04 -6.2 16.5 3.8 1 1 0 1 1 0 0 Syntaxin Ax_dynein_light PF10211.4 GAP82978.1 - 2.7 7.7 12.2 2.4 7.9 2.7 2.6 1 1 2 3 3 3 0 Axonemal dynein light chain DUF4600 PF15372.1 GAP82978.1 - 4.2 7.6 13.7 42 4.3 1.4 3.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) DUF3510 PF12022.3 GAP82978.1 - 4.4 7.4 9.3 15 5.7 0.5 2.8 1 1 2 3 3 2 0 Domain of unknown function (DUF3510) GrpE PF01025.14 GAP82978.1 - 4.9 6.6 14.2 31 4.0 1.1 2.8 1 1 1 2 2 2 0 GrpE GLE1 PF07817.8 GAP82978.1 - 5 5.9 16.0 4.5 6.1 3.0 2.7 1 1 1 2 2 2 0 GLE1-like protein Lectin_N PF03954.9 GAP82978.1 - 5.5 6.3 11.9 9.5 5.6 2.3 2.6 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF3708 PF12501.3 GAP82978.1 - 5.7 6.7 9.7 5.7e+02 0.2 6.7 2.4 1 1 0 1 1 1 0 Phosphate ATP-binding cassette transporter Fib_alpha PF08702.5 GAP82978.1 - 6.2 6.9 24.6 14 5.7 9.9 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family YgaB PF14182.1 GAP82978.1 - 7.1 6.9 10.8 3.1 8.1 0.8 3.5 1 1 1 3 3 3 0 YgaB-like protein ADH_N PF08240.7 GAP82979.1 - 4.6e-22 77.8 1.4 8.4e-22 77.0 1.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAP82979.1 - 1.9e-13 50.1 0.0 3.4e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 GAP82979.1 - 0.00034 19.8 0.2 0.00057 19.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 GAP82979.1 - 0.01 15.4 0.8 0.019 14.5 0.6 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 GAP82979.1 - 0.12 11.9 0.4 0.18 11.3 0.3 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase adh_short PF00106.20 GAP82980.1 - 1.3e-09 38.1 1.4 1.6e-05 24.8 0.1 3.3 2 1 1 3 3 3 3 short chain dehydrogenase NAD_binding_10 PF13460.1 GAP82980.1 - 0.00031 20.8 1.1 0.0031 17.5 0.8 2.3 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 GAP82980.1 - 0.0015 18.2 0.2 0.0033 17.1 0.1 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 GAP82980.1 - 0.0019 17.6 0.0 0.0043 16.5 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family CBFD_NFYB_HMF PF00808.18 GAP82981.1 - 7e-11 42.0 0.1 1.3e-10 41.1 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAP82981.1 - 2.6e-07 30.6 0.0 4.5e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Pox_Ag35 PF03286.9 GAP82981.1 - 0.0024 17.4 1.5 0.0024 17.4 1.1 3.2 2 1 1 3 3 3 2 Pox virus Ag35 surface protein zf-UDP PF14569.1 GAP82981.1 - 0.17 11.6 0.0 0.17 11.6 0.0 2.4 3 0 0 3 3 3 0 Zinc-binding RING-finger HLH PF00010.21 GAP82982.1 - 1.1e-12 47.3 1.4 2.2e-12 46.4 0.1 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Tetraspannin PF00335.15 GAP82983.1 - 0.15 11.3 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF1183 PF06682.7 GAP82983.1 - 0.38 10.3 3.6 7.6 6.0 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) Pkinase PF00069.20 GAP82984.1 - 3.1e-67 226.4 0.0 5.8e-67 225.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP82984.1 - 6e-36 123.8 0.0 1.2e-35 122.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP82984.1 - 3.3e-06 26.2 0.0 7.8e-06 25.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 GAP82984.1 - 0.028 13.2 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 SLD3 PF08639.5 GAP82985.1 - 6.2e-110 368.1 5.4 1.2e-109 367.2 3.7 1.4 1 0 0 1 1 1 1 DNA replication regulator SLD3 TarH PF02203.10 GAP82985.1 - 0.034 13.9 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue RNB PF00773.14 GAP82986.1 - 8.2e-94 314.5 0.0 1.2e-93 313.9 0.0 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 GAP82986.1 - 1.4e-09 38.1 0.6 5.2e-09 36.3 0.1 2.3 2 1 0 2 2 2 1 PIN domain CRC_subunit PF08624.5 GAP82988.1 - 1.6e-54 183.5 0.0 2.2e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit GN3L_Grn1 PF08701.6 GAP82989.1 - 5.3e-27 93.5 17.0 9.3e-27 92.7 11.8 1.4 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 GAP82989.1 - 2.5e-20 72.5 0.1 6.5e-14 51.8 0.0 2.7 2 1 1 3 3 3 2 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAP82989.1 - 1.6e-06 27.7 0.0 0.041 13.3 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 GAP82989.1 - 8.8e-06 25.6 7.4 0.034 13.9 0.0 3.9 3 1 1 4 4 4 2 Dynamin family FeoB_N PF02421.13 GAP82989.1 - 0.00067 18.9 0.1 0.019 14.2 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 GAP82989.1 - 0.0012 18.0 0.2 0.0023 17.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 GAP82989.1 - 0.0087 16.5 1.4 2.8 8.4 0.1 2.6 2 0 0 2 2 2 2 Miro-like protein Arf PF00025.16 GAP82989.1 - 0.033 13.4 0.0 0.36 10.0 0.0 2.2 1 1 1 2 2 2 0 ADP-ribosylation factor family IIGP PF05049.8 GAP82989.1 - 0.04 12.7 1.1 0.042 12.6 0.0 1.5 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) ArgK PF03308.11 GAP82989.1 - 0.052 12.3 0.1 0.052 12.3 0.1 2.3 2 0 0 2 2 2 0 ArgK protein cobW PF02492.14 GAP82989.1 - 0.14 11.5 0.2 0.81 9.1 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF1675 PF07897.6 GAP82989.1 - 1.3 8.8 5.7 0.14 12.0 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) AAA_16 PF13191.1 GAP82989.1 - 3.3 7.6 7.1 0.35 10.8 0.2 2.6 3 0 0 3 3 3 0 AAA ATPase domain Ank_2 PF12796.2 GAP82990.1 - 3.7e-39 132.9 0.3 4e-19 68.7 0.1 4.6 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAP82990.1 - 4.3e-33 111.4 7.5 7.4e-10 38.1 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 GAP82990.1 - 3.9e-24 84.1 15.8 6.1e-10 39.0 0.5 5.6 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAP82990.1 - 3.4e-23 81.5 5.6 2.1e-09 37.6 0.1 6.6 4 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP82990.1 - 6.4e-23 78.5 3.1 0.00013 21.8 0.0 7.0 7 0 0 7 7 6 5 Ankyrin repeat NACHT PF05729.7 GAP82990.1 - 8e-08 32.1 0.1 1.6e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 GAP82990.1 - 1.2e-06 28.6 0.2 3.7e-06 27.0 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAP82990.1 - 1.3e-06 28.5 0.0 4.9e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 GAP82990.1 - 0.00058 18.9 0.6 0.022 13.7 0.1 2.2 1 1 0 2 2 2 1 KAP family P-loop domain AAA PF00004.24 GAP82990.1 - 0.0067 16.6 0.0 0.027 14.6 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 GAP82990.1 - 0.0074 15.1 0.0 0.018 13.8 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.17 GAP82990.1 - 0.023 14.8 0.0 0.055 13.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 GAP82990.1 - 0.09 12.2 0.1 0.29 10.5 0.0 1.9 2 1 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 GAP82990.1 - 0.098 13.4 2.6 0.25 12.1 0.1 2.9 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.22 GAP82990.1 - 0.11 12.7 0.0 0.35 11.1 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 GAP82990.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase cobW PF02492.14 GAP82990.1 - 0.23 10.9 0.0 0.46 9.9 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PNP_UDP_1 PF01048.15 GAP82991.1 - 0.01 14.8 0.0 0.043 12.7 0.0 2.1 3 0 0 3 3 3 0 Phosphorylase superfamily Ank_2 PF12796.2 GAP82993.1 - 9.5e-43 144.4 12.1 8.9e-15 54.8 0.6 4.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAP82993.1 - 6.8e-30 101.3 15.2 3.2e-08 32.9 0.1 8.5 8 0 0 8 8 8 5 Ankyrin repeat Ank_3 PF13606.1 GAP82993.1 - 3.7e-22 76.1 8.2 4.3e-06 26.4 0.0 8.5 8 0 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.1 GAP82993.1 - 2.3e-21 75.7 6.3 4.9e-10 39.6 0.0 5.9 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP82993.1 - 8.5e-21 73.5 12.2 3.5e-07 30.2 0.0 7.1 4 1 3 7 7 7 5 Ankyrin repeats (many copies) HET PF06985.6 GAP82993.1 - 8.4e-20 71.3 10.4 5.7e-18 65.4 2.5 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF1109 PF06532.6 GAP82999.1 - 0.015 14.6 0.1 0.023 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1109) Granulin PF00396.13 GAP82999.1 - 0.041 13.9 4.5 0.18 11.9 0.7 2.3 2 0 0 2 2 2 0 Granulin HAD_2 PF13419.1 GAP83000.1 - 1.7e-18 67.4 0.0 2.1e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAP83000.1 - 3.7e-10 40.5 0.0 4.7e-08 33.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAP83000.1 - 2.3e-07 30.4 0.0 4.6e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 GAP83000.1 - 7.8e-06 26.1 0.0 9.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 GAP83000.1 - 0.014 15.2 0.0 0.19 11.6 0.0 2.5 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase GHL6 PF14871.1 GAP83000.1 - 0.12 12.4 0.0 0.33 10.9 0.0 1.7 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 Ribosomal_S21 PF01165.15 GAP83001.1 - 0.04 13.3 2.7 0.56 9.6 0.0 3.0 3 0 0 3 3 3 0 Ribosomal protein S21 Homeobox PF00046.24 GAP83003.1 - 2.3e-16 59.1 0.5 5e-16 58.0 0.4 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 GAP83003.1 - 9.3e-06 25.2 0.2 2.3e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain CENP-B_dimeris PF09026.5 GAP83003.1 - 0.021 15.0 12.7 0.046 13.9 8.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 GAP83003.1 - 0.34 10.4 9.3 0.59 9.6 6.5 1.4 1 0 0 1 1 1 0 Nucleoplasmin TRAP_alpha PF03896.11 GAP83003.1 - 0.93 8.4 5.4 1.7 7.5 3.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.7 GAP83003.1 - 4.6 5.0 18.9 6.1 4.6 13.1 1.1 1 0 0 1 1 1 0 Nop14-like family Fungal_trans PF04082.13 GAP83004.1 - 5.4e-17 61.5 0.0 8.8e-17 60.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP83004.1 - 2.3e-06 27.3 13.9 3.6e-06 26.7 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAP83005.1 - 1.4e-20 73.2 1.0 2.2e-20 72.6 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP83005.1 - 1.6e-07 31.0 9.3 2.7e-07 30.3 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 GAP83006.1 - 2.7e-95 319.5 22.7 3.1e-95 319.4 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP83006.1 - 1.2e-29 103.1 35.7 7.6e-24 84.0 9.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAP83006.1 - 0.00046 18.7 1.1 0.00046 18.7 0.7 3.6 1 1 2 3 3 3 2 MFS/sugar transport protein M20_dimer PF07687.9 GAP83007.1 - 1.9e-05 24.3 0.1 4.3e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 GAP83007.1 - 0.0001 21.8 9.6 0.00024 20.6 6.7 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Arginosuc_synth PF00764.14 GAP83008.1 - 1.2e-08 34.3 0.0 9.1e-08 31.5 0.0 1.9 1 1 0 1 1 1 1 Arginosuccinate synthase TPR_9 PF13371.1 GAP83009.1 - 6.4e-05 22.7 0.0 0.0003 20.5 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat Glyco_hydro_7 PF00840.15 GAP83010.1 - 8.6e-208 689.9 23.7 1e-207 689.7 16.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Abhydrolase_5 PF12695.2 GAP83011.1 - 0.0057 16.4 1.2 0.01 15.6 0.3 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP83011.1 - 0.64 9.8 9.2 0.055 13.3 1.2 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase family CorA PF01544.13 GAP83012.1 - 2.6e-10 39.8 2.8 2.9e-09 36.3 1.0 2.5 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Zot PF05707.7 GAP83012.1 - 0.0036 16.7 0.1 0.015 14.7 0.0 2.1 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) EXS PF03124.9 GAP83012.1 - 0.016 14.2 1.0 0.023 13.7 0.7 1.2 1 0 0 1 1 1 0 EXS family DUF3947 PF13135.1 GAP83012.1 - 3.4 7.9 5.2 56 4.0 3.6 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3947) DHDPS PF00701.17 GAP83013.1 - 2.1e-21 75.8 0.0 2.2e-20 72.4 0.0 2.0 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family Glyco_hydro_17 PF00332.13 GAP83014.1 - 0.0017 17.4 1.3 0.0078 15.2 0.9 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Glyco_hydro_53 PF07745.8 GAP83014.1 - 0.013 14.3 0.0 0.021 13.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 RE_XcyI PF09571.5 GAP83014.1 - 0.036 12.9 0.0 0.065 12.0 0.0 1.3 1 0 0 1 1 1 0 XcyI restriction endonuclease 2OG-FeII_Oxy_3 PF13640.1 GAP83015.1 - 1.4e-09 38.4 0.0 2.1e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 GAP83015.1 - 0.02 14.5 0.1 0.043 13.4 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily zf-MYND PF01753.13 GAP83016.1 - 7.5e-09 35.3 7.9 9.8e-09 34.9 5.5 1.2 1 0 0 1 1 1 1 MYND finger C1_3 PF07649.7 GAP83016.1 - 0.035 14.1 0.4 0.067 13.2 0.3 1.5 1 0 0 1 1 1 0 C1-like domain Glyco_hydro_28 PF00295.12 GAP83017.1 - 4.3e-43 147.5 3.9 6.4e-43 146.9 2.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_76 PF03663.9 GAP83018.1 - 5.4e-122 407.7 17.9 2.6e-107 359.4 10.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 GAP83018.1 - 0.061 12.3 6.6 0.89 8.5 0.1 3.0 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 RRM_1 PF00076.17 GAP83021.1 - 2.3e-19 68.7 0.3 2.3e-11 43.1 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP83021.1 - 8.1e-19 67.3 0.0 1.5e-08 34.5 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP83021.1 - 0.00015 21.5 0.5 0.033 14.0 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAP83021.1 - 0.0096 15.7 1.9 0.018 14.8 0.2 2.2 2 0 0 2 2 2 1 RNA binding motif PcfJ PF14284.1 GAP83022.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 PcfJ-like protein PRELI PF04707.9 GAP83023.1 - 2.8e-42 143.9 1.3 3.4e-42 143.6 0.9 1.1 1 0 0 1 1 1 1 PRELI-like family GATase_3 PF07685.9 GAP83023.1 - 0.011 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Ank PF00023.25 GAP83024.1 - 1.8e-61 201.0 5.6 2.1e-10 39.8 0.0 8.1 8 0 0 8 8 8 6 Ankyrin repeat Ank_2 PF12796.2 GAP83024.1 - 1.2e-54 182.5 16.0 4.1e-20 71.9 0.5 4.9 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAP83024.1 - 6.5e-46 153.9 8.8 8.5e-12 45.2 0.1 6.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP83024.1 - 1.6e-39 129.9 4.6 5.8e-07 29.1 0.0 8.5 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 GAP83024.1 - 2.1e-38 129.4 3.3 1.7e-12 47.1 0.0 5.2 3 1 2 5 5 5 5 Ankyrin repeats (many copies) NACHT PF05729.7 GAP83024.1 - 2.4e-06 27.2 0.2 9.8e-06 25.3 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 GAP83024.1 - 2.8e-06 27.4 0.0 8.6e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAP83024.1 - 0.0055 16.8 0.0 0.023 14.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 GAP83024.1 - 0.011 15.2 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain KAP_NTPase PF07693.9 GAP83024.1 - 0.024 13.6 0.7 0.13 11.2 0.0 2.3 2 1 0 3 3 3 0 KAP family P-loop domain S-methyl_trans PF02574.11 GAP83024.1 - 0.025 13.8 0.0 1.6 7.9 0.0 2.5 1 1 1 2 2 2 0 Homocysteine S-methyltransferase Sigma54_activ_2 PF14532.1 GAP83024.1 - 0.074 13.0 0.0 0.7 9.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.24 GAP83024.1 - 0.078 13.1 0.0 0.61 10.2 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RVP PF00077.15 GAP83024.1 - 0.19 11.6 5.4 6.4 6.7 0.0 4.7 4 1 1 5 5 5 0 Retroviral aspartyl protease YcgL PF05166.8 GAP83024.1 - 0.19 11.8 1.6 24 5.1 0.0 3.9 2 1 2 4 4 4 0 YcgL domain PepSY_2 PF13670.1 GAP83025.1 - 3 7.8 5.1 0.89 9.4 1.1 1.9 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Pyr_redox_3 PF13738.1 GAP83029.1 - 9.1e-25 87.9 0.0 4.4e-23 82.4 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAP83029.1 - 8.3e-11 42.1 0.0 8.4e-09 35.6 0.0 2.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAP83029.1 - 1e-08 34.5 0.1 4.3e-06 25.8 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 GAP83029.1 - 3.7e-08 32.0 0.0 2.1e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 GAP83029.1 - 5.3e-07 29.5 0.0 4.8e-06 26.5 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 GAP83029.1 - 4.8e-06 25.8 0.0 4.9e-05 22.5 0.0 2.4 3 0 0 3 3 3 1 FAD binding domain FAD_binding_2 PF00890.19 GAP83029.1 - 4.2e-05 22.5 0.5 0.00011 21.2 0.6 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 GAP83029.1 - 5.1e-05 23.5 0.1 0.5 10.7 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SnoaL_2 PF12680.2 GAP83029.1 - 6.7e-05 23.2 0.1 0.00024 21.4 0.0 2.0 2 0 0 2 2 1 1 SnoaL-like domain Shikimate_DH PF01488.15 GAP83029.1 - 7.1e-05 22.9 0.1 0.57 10.2 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 GAP83029.1 - 0.00018 20.5 1.0 0.0033 16.3 0.3 2.3 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.9 GAP83029.1 - 0.00029 19.4 0.3 0.00087 17.8 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 GAP83029.1 - 0.00055 18.9 0.5 0.0073 15.2 0.1 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAP83029.1 - 0.0014 17.7 0.0 0.0086 15.1 0.0 2.0 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 GAP83029.1 - 0.0036 16.4 0.1 0.0086 15.1 0.2 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 GAP83029.1 - 0.0038 16.3 0.1 0.03 13.4 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 GAP83029.1 - 0.0048 17.1 0.0 4.8 7.4 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_9 PF13454.1 GAP83029.1 - 0.024 14.4 0.0 3.4 7.4 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 GAP83029.1 - 0.04 13.5 1.1 6.6 6.3 0.1 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 GAP83029.1 - 0.041 13.8 0.1 0.42 10.6 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain AlaDh_PNT_C PF01262.16 GAP83029.1 - 0.041 13.4 0.1 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SnoaL_4 PF13577.1 GAP83029.1 - 0.06 13.2 0.2 0.35 10.7 0.1 2.2 1 1 0 1 1 1 0 SnoaL-like domain ThiF PF00899.16 GAP83029.1 - 0.083 12.7 0.3 0.21 11.4 0.2 1.7 1 0 0 1 1 1 0 ThiF family Lycopene_cycl PF05834.7 GAP83029.1 - 0.11 11.3 0.1 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Grp1_Fun34_YaaH PF01184.14 GAP83030.1 - 2.4e-28 98.8 16.4 3.2e-28 98.4 11.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Dicty_CAR PF05462.6 GAP83030.1 - 0.15 10.9 4.9 0.2 10.5 3.4 1.1 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor DUF3671 PF12420.3 GAP83030.1 - 0.19 11.7 0.3 1.4 8.9 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function ADH_zinc_N PF00107.21 GAP83032.1 - 1.6e-06 27.6 0.0 2.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 3A PF00803.13 GAP83032.1 - 0.13 11.2 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 3A/RNA2 movement protein family F-box-like PF12937.2 GAP83033.1 - 0.00039 20.0 0.8 0.0011 18.7 0.6 1.8 1 0 0 1 1 1 1 F-box-like GMC_oxred_N PF00732.14 GAP83034.1 - 1.4e-30 106.4 0.0 3.8e-30 105.0 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAP83034.1 - 1.5e-22 80.4 0.0 3.1e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAP83034.1 - 0.00018 20.5 0.1 0.27 10.1 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAP83034.1 - 0.0049 16.7 0.9 0.03 14.2 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP83034.1 - 0.006 16.6 0.6 2.2 8.3 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAP83034.1 - 0.011 14.7 0.0 0.018 13.9 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAP83034.1 - 0.013 14.3 1.9 0.032 13.0 0.3 2.2 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 GAP83034.1 - 0.14 11.1 0.4 0.34 9.9 0.0 1.8 2 0 0 2 2 2 0 Thi4 family HET PF06985.6 GAP83035.1 - 1.2e-19 70.8 0.0 2.8e-19 69.6 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UTP15_C PF09384.5 GAP83036.1 - 5.2e-41 139.7 0.1 8.1e-41 139.1 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 GAP83036.1 - 2.6e-26 90.4 7.5 7.1e-10 38.3 0.1 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat ECH PF00378.15 GAP83037.1 - 4.4e-38 130.7 0.3 8.9e-38 129.7 0.2 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 GAP83037.1 - 0.0064 16.6 0.1 0.011 15.8 0.1 1.4 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region Tbf5 PF06331.7 GAP83038.1 - 1.5e-26 91.9 1.6 1.6e-26 91.8 1.1 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Aldo_ket_red PF00248.16 GAP83040.1 - 2.6e-69 233.1 0.0 3e-69 232.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FliG_M PF14841.1 GAP83040.1 - 0.052 13.5 0.1 0.094 12.7 0.1 1.3 1 0 0 1 1 1 0 FliG middle domain PspB PF06667.7 GAP83041.1 - 0.24 11.3 1.7 7.6 6.5 0.1 2.5 1 1 0 2 2 2 0 Phage shock protein B Ribosomal_L16 PF00252.13 GAP83043.1 - 6.7e-31 106.7 0.1 8.8e-31 106.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L7Ae PF01248.21 GAP83044.1 - 2.4e-24 84.6 0.0 2.8e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Rotamase PF00639.16 GAP83045.1 - 0.42 11.3 0.0 0.42 11.3 0.0 3.6 2 1 1 3 3 3 0 PPIC-type PPIASE domain Z1 PF10593.4 GAP83045.1 - 4.5 6.4 11.1 3.6 6.7 6.0 1.9 1 1 1 2 2 2 0 Z1 domain V_ATPase_I PF01496.14 GAP83045.1 - 6.2 4.5 12.5 2.2 6.0 6.5 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Vac7 PF12751.2 GAP83046.1 - 1e-125 419.6 2.1 1e-125 419.6 1.5 2.2 2 1 0 2 2 2 1 Vacuolar segregation subunit 7 PRP1_N PF06424.7 GAP83047.1 - 4.9e-47 159.6 5.8 5.8e-29 101.1 1.3 2.9 2 0 0 2 2 2 2 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 GAP83047.1 - 4.6e-32 107.5 40.6 1.7e-05 25.0 0.4 14.2 4 2 10 15 15 14 12 Tetratricopeptide repeat TPR_19 PF14559.1 GAP83047.1 - 9.4e-29 99.5 20.2 8e-09 35.7 0.7 9.1 6 2 3 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 GAP83047.1 - 4.6e-21 74.9 33.7 2.5e-06 28.0 1.4 10.0 7 2 3 11 11 11 5 Tetratricopeptide repeat TPR_11 PF13414.1 GAP83047.1 - 1.1e-15 57.0 11.6 6e-06 25.8 0.1 7.5 7 1 1 8 8 8 3 TPR repeat TPR_2 PF07719.12 GAP83047.1 - 1.7e-13 49.3 10.3 0.26 11.3 0.0 10.0 10 1 1 11 11 11 4 Tetratricopeptide repeat TPR_15 PF13429.1 GAP83047.1 - 2.3e-08 33.4 22.4 0.0029 16.6 5.7 6.2 2 2 3 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 GAP83047.1 - 1.3e-07 31.2 2.2 2.7 8.4 0.0 8.4 9 1 1 10 10 10 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAP83047.1 - 4.2e-07 29.9 12.0 13 6.5 0.0 9.9 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAP83047.1 - 2.2e-06 27.0 0.0 0.29 11.0 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat NARP1 PF12569.3 GAP83047.1 - 5.2e-06 25.4 0.3 0.45 9.2 0.0 4.9 4 2 2 6 6 6 2 NMDA receptor-regulated protein 1 NRDE-2 PF08424.5 GAP83047.1 - 7.4e-06 25.0 15.0 4.9e-05 22.3 0.4 4.1 3 2 1 4 4 4 3 NRDE-2, necessary for RNA interference TPR_1 PF00515.23 GAP83047.1 - 1.1e-05 24.8 0.6 2.7 7.7 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat Suf PF05843.9 GAP83047.1 - 2.2e-05 24.3 0.1 0.34 10.6 0.0 4.9 4 1 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_12 PF13424.1 GAP83047.1 - 0.00018 21.3 11.7 0.24 11.3 0.0 6.0 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAP83047.1 - 0.057 13.2 8.0 70 3.5 0.0 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat Cutinase PF01083.17 GAP83047.1 - 0.098 12.3 1.1 1.4 8.6 0.0 3.1 3 1 1 4 4 4 0 Cutinase TPR_10 PF13374.1 GAP83047.1 - 1.9 8.4 15.1 3.9 7.5 0.1 5.6 5 0 0 5 5 4 0 Tetratricopeptide repeat RrnaAD PF00398.15 GAP83048.1 - 1.3e-55 188.2 0.0 1.9e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 GAP83048.1 - 3.1e-10 40.1 0.0 5.1e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP83048.1 - 1.2e-07 32.2 0.0 2.5e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP83048.1 - 1.3e-05 24.8 0.0 2.8e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 GAP83048.1 - 1.9e-05 24.1 0.0 3.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 GAP83048.1 - 0.00015 22.1 0.0 0.00033 21.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 GAP83048.1 - 0.00022 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.11 GAP83048.1 - 0.00029 20.4 0.0 0.00056 19.5 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_12 PF08242.7 GAP83048.1 - 0.001 19.5 0.0 0.0021 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP83048.1 - 0.0043 16.7 0.0 0.0071 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 GAP83048.1 - 0.014 14.5 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 GAP83048.1 - 0.015 14.3 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.1 GAP83048.1 - 0.024 14.9 0.0 0.049 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 GAP83048.1 - 0.052 12.7 0.0 0.087 12.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase PrmA PF06325.8 GAP83048.1 - 0.059 12.4 0.0 0.094 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 GAP83048.1 - 0.061 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_28 PF02636.12 GAP83048.1 - 0.096 12.0 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Apolipoprotein PF01442.13 GAP83049.1 - 0.0011 18.5 0.9 0.0014 18.2 0.6 1.0 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 GAP83049.1 - 1.4 9.3 7.8 0.94 9.9 4.0 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF3439 PF11921.3 GAP83050.1 - 0.62 9.8 14.5 1.1 8.9 10.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 GAP83050.1 - 7.8 6.2 27.6 0.44 10.3 15.3 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein Hemerythrin PF01814.18 GAP83051.1 - 0.02 15.0 11.8 0.058 13.5 0.1 2.6 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain He_PIG PF05345.7 GAP83052.1 - 1.6e-15 56.8 7.8 0.0001 22.2 0.8 4.1 3 0 0 3 3 3 3 Putative Ig domain PP2C PF00481.16 GAP83053.1 - 8.5e-81 271.0 0.0 1.3e-80 270.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 GAP83053.1 - 0.00056 19.3 0.0 0.0013 18.2 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C PPR_2 PF13041.1 GAP83054.1 - 4.9e-05 23.2 0.1 0.016 15.1 0.0 3.2 3 0 0 3 3 3 1 PPR repeat family KH_3 PF13014.1 GAP83054.1 - 0.0029 17.2 0.5 0.089 12.4 0.0 2.4 2 0 0 2 2 2 1 KH domain KH_1 PF00013.24 GAP83054.1 - 0.0079 15.8 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 2 KH domain DUF1858 PF08984.6 GAP83054.1 - 0.067 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1858) PPR_3 PF13812.1 GAP83054.1 - 0.14 12.4 1.1 9.6 6.7 0.0 3.5 3 0 0 3 3 3 0 Pentatricopeptide repeat domain Peptidase_M20 PF01546.23 GAP83055.1 - 2.1e-33 115.4 0.0 3.3e-33 114.7 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAP83055.1 - 6.2e-14 51.7 0.0 1.1e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Methyltransf_16 PF10294.4 GAP83056.1 - 3.3e-44 150.3 0.0 4.4e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 GAP83056.1 - 2.1e-05 25.0 0.0 3.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP83056.1 - 0.0056 16.4 0.0 0.0085 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP83056.1 - 0.013 15.0 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 GAP83056.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DPBB_1 PF03330.13 GAP83057.1 - 0.00014 21.8 0.0 0.0013 18.6 0.0 2.3 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel PAT1 PF09770.4 GAP83057.1 - 0.58 8.3 14.8 0.72 8.0 10.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1712 PF08217.6 GAP83058.1 - 3.5e-14 51.9 0.0 5.1e-12 44.8 0.0 2.8 3 0 0 3 3 3 2 Fungal domain of unknown function (DUF1712) TRP PF06011.7 GAP83059.1 - 9.6e-148 492.3 28.9 1.2e-147 492.0 20.0 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 GAP83059.1 - 1.6e-43 148.1 1.7 2.7e-43 147.4 1.2 1.4 1 0 0 1 1 1 1 ML-like domain Glyco_hydro_35 PF01301.14 GAP83060.1 - 7.4e-83 278.5 0.0 1.1e-82 277.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 GAP83060.1 - 4.4e-07 30.1 0.0 9.4e-06 25.8 0.0 2.8 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain Oxysterol_BP PF01237.13 GAP83061.1 - 5.3e-110 367.2 0.0 9.2e-110 366.4 0.0 1.4 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 GAP83061.1 - 3.1e-37 126.5 0.1 8.7e-37 125.0 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 GAP83061.1 - 0.00045 20.3 0.0 0.00098 19.2 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAP83061.1 - 0.00052 20.2 1.4 0.026 14.7 1.0 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain GOLD_2 PF13897.1 GAP83061.1 - 0.0047 17.1 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Golgi-dynamics membrane-trafficking SH2_2 PF14633.1 GAP83062.1 - 1.7e-84 282.2 0.1 1.7e-84 282.2 0.1 2.3 2 0 0 2 2 2 1 SH2 domain DLD PF14878.1 GAP83062.1 - 3.1e-35 120.7 3.0 3.1e-35 120.7 2.1 3.5 4 0 0 4 4 4 1 Death-like domain of SPT6 YqgF PF14639.1 GAP83062.1 - 4.9e-34 117.0 0.0 1.4e-33 115.5 0.0 1.9 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.1 GAP83062.1 - 7.2e-30 103.1 0.0 1.8e-29 101.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.1 GAP83062.1 - 1.3e-23 82.9 32.2 1.3e-23 82.9 22.3 5.4 6 0 0 6 6 6 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 GAP83062.1 - 5.6e-19 68.3 2.3 5.4e-18 65.1 1.6 2.7 1 1 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 GAP83062.1 - 4.8e-06 26.2 0.0 1.2e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 SH2 domain S1 PF00575.18 GAP83062.1 - 0.00088 19.3 0.2 0.0022 18.0 0.1 1.8 1 0 0 1 1 1 1 S1 RNA binding domain HHH_3 PF12836.2 GAP83062.1 - 0.0087 15.9 0.0 0.025 14.5 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif B12-binding PF02310.14 GAP83062.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain Pkinase PF00069.20 GAP83063.1 - 3.5e-60 203.3 0.0 4.5e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP83063.1 - 4.7e-38 130.7 0.0 6.4e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP83063.1 - 8.5e-06 24.9 0.1 3.7e-05 22.8 0.0 1.9 3 0 0 3 3 3 1 Kinase-like Hydrolase PF00702.21 GAP83064.1 - 4.4e-07 30.5 0.0 0.0001 22.7 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAP83064.1 - 1.7e-06 27.6 0.9 2.8e-06 26.9 0.7 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 GAP83064.1 - 0.0072 16.5 0.0 2.9 8.0 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Filament PF00038.16 GAP83065.1 - 6.1e-06 25.9 10.4 6.1e-06 25.9 7.2 4.3 4 2 1 5 5 5 2 Intermediate filament protein UBN2_3 PF14244.1 GAP83065.1 - 0.01 15.3 0.9 1.2 8.6 0.0 2.8 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Reo_sigmaC PF04582.7 GAP83065.1 - 0.097 11.8 11.6 0.27 10.3 1.1 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF4320 PF14208.1 GAP83065.1 - 0.43 10.5 2.9 1.1 9.1 0.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4320) p450 PF00067.17 GAP83066.1 - 7.1e-41 140.2 0.0 2.3e-27 95.6 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 DUF3956 PF13104.1 GAP83066.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) Ank_2 PF12796.2 GAP83069.1 - 1.4e-84 278.5 16.5 2.4e-13 50.2 0.0 9.7 6 2 4 10 10 10 8 Ankyrin repeats (3 copies) Ank PF00023.25 GAP83069.1 - 5.3e-61 199.5 40.2 7.9e-06 25.4 0.0 19.3 20 0 0 20 20 20 14 Ankyrin repeat Ank_4 PF13637.1 GAP83069.1 - 5.6e-50 166.8 15.8 1.9e-07 31.3 0.1 14.4 9 3 6 15 15 15 13 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP83069.1 - 7.6e-42 137.1 27.2 0.00022 21.1 0.0 18.6 19 1 1 20 20 20 9 Ankyrin repeat Ank_5 PF13857.1 GAP83069.1 - 3.3e-40 135.1 30.0 3.5e-05 23.8 0.1 13.8 6 5 7 14 14 14 9 Ankyrin repeats (many copies) Abhydrolase_6 PF12697.2 GAP83069.1 - 1.7e-06 28.1 0.3 2.9e-05 24.0 0.0 3.1 3 0 0 3 3 3 1 Alpha/beta hydrolase family DUF676 PF05057.9 GAP83069.1 - 0.016 14.5 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.8 GAP83069.1 - 0.036 13.6 0.0 0.091 12.3 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein SNARE_assoc PF09335.6 GAP83071.1 - 0.006 16.7 0.1 0.0086 16.2 0.0 1.2 1 0 0 1 1 1 1 SNARE associated Golgi protein Ank_2 PF12796.2 GAP83072.1 - 1.5e-62 207.9 12.2 4.5e-19 68.5 0.0 9.2 3 3 5 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 GAP83072.1 - 1.3e-42 141.5 25.7 4.5e-06 26.2 0.1 16.2 16 2 0 16 16 16 9 Ankyrin repeat Ank_4 PF13637.1 GAP83072.1 - 3.2e-39 132.6 15.0 3.4e-10 40.1 0.0 11.7 8 2 5 13 13 13 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP83072.1 - 1.8e-37 123.6 16.6 7.1e-05 22.6 0.0 17.0 19 0 0 19 19 19 6 Ankyrin repeat Ank_5 PF13857.1 GAP83072.1 - 1.2e-24 85.7 21.9 0.0018 18.4 0.0 12.2 9 1 3 12 12 12 7 Ankyrin repeats (many copies) p450 PF00067.17 GAP83073.1 - 6.8e-47 160.0 0.0 9.9e-47 159.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Nepo_coat_C PF03688.9 GAP83074.1 - 0.019 14.5 0.1 0.031 13.8 0.1 1.3 1 0 0 1 1 1 0 Nepovirus coat protein, C-terminal domain Hce2 PF14856.1 GAP83075.1 - 1.3e-10 41.0 0.1 1.7e-10 40.6 0.1 1.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor zf-C2H2 PF00096.21 GAP83077.1 - 1.2e-05 25.3 8.7 0.022 15.0 0.2 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP83077.1 - 6.3e-05 23.0 10.4 0.008 16.4 0.6 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger ALIX_LYPXL_bnd PF13949.1 GAP83077.1 - 0.0056 15.6 0.2 0.0079 15.1 0.1 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV zf-H2C2_2 PF13465.1 GAP83077.1 - 0.062 13.6 12.4 0.084 13.2 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double domain DUF1509 PF07420.6 GAP83077.1 - 5.1 6.2 25.4 3 7.0 6.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1509) DUF1680 PF07944.7 GAP83078.1 - 1.4e-96 323.8 0.0 2e-96 323.3 0.0 1.2 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) BCS1_N PF08740.6 GAP83079.1 - 6.8e-30 104.0 0.1 1e-29 103.5 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 GAP83079.1 - 6.8e-23 81.3 0.0 1.3e-22 80.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 GAP83079.1 - 0.00019 20.5 0.0 0.00035 19.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 GAP83079.1 - 0.0002 22.1 0.0 0.0005 20.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAP83079.1 - 0.0088 16.0 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 GAP83079.1 - 0.012 15.8 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 GAP83079.1 - 0.016 14.9 0.0 0.039 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 GAP83079.1 - 0.021 15.1 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 GAP83079.1 - 0.027 13.4 0.0 0.042 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.1 GAP83079.1 - 0.034 14.0 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 GAP83079.1 - 0.038 13.3 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 GAP83079.1 - 0.052 12.9 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAP83079.1 - 0.1 12.7 0.0 0.29 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 GAP83079.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pyr_redox_3 PF13738.1 GAP83080.1 - 9.7e-27 94.3 0.0 1.6e-25 90.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAP83080.1 - 3e-17 62.0 0.0 1.7e-11 43.0 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 GAP83080.1 - 9.1e-09 35.4 0.0 3.2e-07 30.4 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAP83080.1 - 6e-08 31.9 0.0 3.3e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 GAP83080.1 - 1.7e-05 24.6 0.1 0.0046 16.7 0.1 3.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 GAP83080.1 - 9.9e-05 21.5 0.1 0.015 14.3 0.0 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.1 GAP83080.1 - 0.0016 18.4 0.0 0.007 16.3 0.0 2.1 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAP83080.1 - 0.0024 16.3 0.0 0.49 8.8 0.0 2.9 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.22 GAP83080.1 - 0.0066 16.8 0.2 7.9 6.9 0.1 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAP83080.1 - 0.011 14.6 0.1 1.4 7.7 0.0 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.17 GAP83080.1 - 0.064 12.1 0.0 5.1 5.8 0.0 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A Bax1-I PF01027.15 GAP83081.1 - 0.038 13.5 0.6 0.038 13.5 0.4 2.4 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 DUF2834 PF11196.3 GAP83081.1 - 0.039 14.1 4.7 0.35 11.0 0.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2834) ketoacyl-synt PF00109.21 GAP83082.1 - 1.5e-60 204.8 0.6 6.3e-60 202.7 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAP83082.1 - 8.5e-60 202.7 0.0 1.4e-59 202.0 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 GAP83082.1 - 1.2e-59 201.8 0.2 2e-59 201.1 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 GAP83082.1 - 1.4e-57 194.2 1.1 1.4e-57 194.2 0.8 2.4 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 GAP83082.1 - 5.6e-47 159.7 2.8 1.7e-46 158.2 0.6 2.9 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAP83082.1 - 9.8e-32 109.3 0.1 3.5e-31 107.5 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 GAP83082.1 - 4e-06 26.0 0.2 8.1e-06 25.0 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 GAP83082.1 - 0.024 14.3 0.3 0.068 12.8 0.2 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SARS_3b PF12383.3 GAP83082.1 - 0.53 10.2 0.0 1.1 9.2 0.0 1.4 1 0 0 1 1 1 0 Severe acute respiratory syndrome coronavirus 3b protein Transferase PF02458.10 GAP83083.1 - 3.1e-11 42.3 0.0 3.8e-11 42.0 0.0 1.0 1 0 0 1 1 1 1 Transferase family Transferase PF02458.10 GAP83084.1 - 0.029 12.8 0.0 0.036 12.5 0.0 1.1 1 0 0 1 1 1 0 Transferase family HET PF06985.6 GAP83086.1 - 5.9e-21 75.0 0.0 1.1e-20 74.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_6 PF01341.12 GAP83087.1 - 4.1e-95 318.6 2.5 5.3e-95 318.2 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 OST3_OST6 PF04756.8 GAP83088.1 - 4.1e-21 75.1 1.8 5.9e-21 74.6 1.2 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Sulf_coat_C PF12193.3 GAP83090.1 - 0.062 13.1 0.1 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 Sulfolobus virus coat protein C terminal FtsJ PF01728.14 GAP83091.1 - 3e-63 213.0 0.0 3.7e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 GAP83091.1 - 1.8e-05 24.5 0.0 3.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP83091.1 - 0.0036 17.8 0.0 0.0073 16.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP83091.1 - 0.084 12.4 0.0 1.5 8.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain MFS_1 PF07690.11 GAP83092.1 - 2.2e-29 102.2 46.9 1.2e-28 99.8 32.5 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAP83092.1 - 5.1e-09 34.8 2.0 5.1e-09 34.8 1.4 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) SRCR_2 PF15494.1 GAP83092.1 - 0.0051 17.0 0.6 0.013 15.7 0.4 1.6 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Stc1 PF12898.2 GAP83092.1 - 0.12 12.4 0.3 0.26 11.3 0.2 1.5 1 0 0 1 1 1 0 Stc1 domain Acyl-CoA_dh_1 PF00441.19 GAP83093.1 - 3.4e-34 118.1 0.3 5.6e-34 117.4 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 GAP83093.1 - 2.9e-21 75.0 0.1 6.7e-21 73.8 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 GAP83093.1 - 2.6e-18 65.2 1.3 5.2e-18 64.3 0.4 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 GAP83093.1 - 9.5e-05 22.9 0.6 0.00027 21.4 0.1 2.1 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 GAP83093.1 - 0.00011 22.5 0.0 0.00025 21.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Amino_oxidase PF01593.19 GAP83094.1 - 1.8e-45 155.9 0.0 4.4e-45 154.5 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAP83094.1 - 6.2e-15 54.9 0.1 1.3e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAP83094.1 - 1.4e-05 25.2 0.3 4.2e-05 23.7 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAP83094.1 - 6e-05 23.0 0.1 0.00034 20.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAP83094.1 - 8.6e-05 22.8 2.4 0.0011 19.2 0.5 3.1 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAP83094.1 - 9.9e-05 21.3 0.0 0.0023 16.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAP83094.1 - 0.00011 20.8 0.1 0.0087 14.5 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 GAP83094.1 - 0.00059 19.0 0.5 0.0011 18.0 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 GAP83094.1 - 0.0013 17.6 0.5 0.0029 16.5 0.3 1.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 GAP83094.1 - 0.0014 18.3 1.1 0.78 9.5 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding 3HCDH_N PF02737.13 GAP83094.1 - 0.0025 17.5 0.4 0.0054 16.4 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 GAP83094.1 - 0.03 13.4 0.1 0.052 12.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 GAP83094.1 - 0.033 13.0 0.4 0.065 12.0 0.3 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 GAP83094.1 - 0.053 12.5 0.1 0.087 11.8 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_10 PF13460.1 GAP83094.1 - 0.13 12.2 0.3 0.29 11.1 0.2 1.7 1 1 0 1 1 1 0 NADH(P)-binding ATG2_CAD PF13329.1 GAP83095.1 - 4.8e-48 162.7 0.1 1.3e-47 161.2 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 GAP83095.1 - 5.9e-30 103.3 0.1 2.1e-29 101.5 0.0 2.1 1 0 0 1 1 1 1 ATG C terminal domain Pex24p PF06398.6 GAP83096.1 - 7.9e-89 297.9 0.0 9.6e-89 297.6 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.3 GAP83096.1 - 0.0017 16.3 0.2 0.0025 15.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) ECR1_N PF14382.1 GAP83097.1 - 5.8e-10 38.3 0.0 1.2e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 GAP83097.1 - 0.051 13.5 0.0 0.58 10.1 0.0 2.3 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 Aldedh PF00171.17 GAP83098.1 - 3e-75 253.3 0.0 3.4e-75 253.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ribosomal_L22e PF01776.12 GAP83099.1 - 1.3e-46 157.2 0.9 1.6e-46 156.9 0.6 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family FluMu_gp41 PF10109.4 GAP83099.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Mu-like prophage FluMu protein gp41 Mito_carr PF00153.22 GAP83100.1 - 2.6e-43 145.6 2.2 1.7e-19 69.3 0.0 3.9 3 1 1 4 4 4 3 Mitochondrial carrier protein PI-PLC-X PF00388.14 GAP83101.1 - 0.01 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain SnoaL PF07366.7 GAP83101.1 - 0.063 12.8 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase Pkinase PF00069.20 GAP83103.1 - 1e-51 175.5 0.0 1.4e-51 175.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP83103.1 - 6.9e-39 133.4 0.0 1e-38 132.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP83103.1 - 0.013 14.4 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 GAP83103.1 - 0.022 13.8 0.0 0.052 12.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CorA PF01544.13 GAP83104.1 - 2.2e-09 36.7 0.0 3.6e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein PIG-F PF06699.6 GAP83105.1 - 1.7e-54 184.6 2.0 2e-54 184.4 1.4 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Bacteriocin_IIc PF10439.4 GAP83105.1 - 3.7 7.7 11.0 1.2 9.3 1.5 2.5 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Translin PF01997.11 GAP83106.1 - 4.5e-48 163.5 0.0 5.6e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Translin family MRP-S28 PF10213.4 GAP83107.1 - 2.8e-45 153.4 0.5 9.1e-44 148.5 0.1 2.3 2 0 0 2 2 2 2 Mitochondrial ribosomal subunit protein Glyco_tran_28_C PF04101.11 GAP83108.1 - 2.5e-13 50.0 0.0 7.8e-13 48.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 GAP83108.1 - 0.001 18.3 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 1 zf-B_box PF00643.19 GAP83109.1 - 0.38 10.6 8.5 1 9.3 1.1 2.6 2 0 0 2 2 2 0 B-box zinc finger MRP-L20 PF12824.2 GAP83110.1 - 1.4e-28 99.9 8.1 1.4e-28 99.9 5.0 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Frankia_peptide PF14407.1 GAP83110.1 - 0.093 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. DUF3096 PF11295.3 GAP83110.1 - 0.12 11.9 0.6 0.19 11.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3096) RasGAP PF00616.14 GAP83113.1 - 3e-42 144.5 0.0 1.1e-41 142.6 0.0 2.0 1 1 1 2 2 2 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 GAP83113.1 - 0.0019 18.0 0.0 0.0044 16.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain Pro_isomerase PF00160.16 GAP83114.1 - 4.4e-45 153.6 0.7 6.3e-45 153.1 0.5 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 GAP83114.1 - 8.3e-07 28.5 4.6 0.0025 17.4 0.7 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 GAP83114.1 - 1.4e-05 24.6 2.2 0.00016 21.2 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAP83114.1 - 0.00031 20.2 0.0 0.002 17.6 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAP83114.1 - 0.0011 19.2 0.0 0.0083 16.5 0.0 2.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAP83114.1 - 0.0032 17.3 1.6 0.02 14.8 0.2 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAP83114.1 - 0.012 16.2 4.5 0.014 16.0 0.9 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAP83114.1 - 0.013 15.1 0.0 0.3 10.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAP83114.1 - 0.034 14.7 0.4 0.034 14.7 0.3 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3176 PF11374.3 GAP83115.1 - 3.5e-31 107.3 3.7 7.6e-31 106.2 2.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) MASE1 PF05231.9 GAP83115.1 - 0.076 12.0 12.7 0.14 11.1 8.8 1.4 1 0 0 1 1 1 0 MASE1 VWA_2 PF13519.1 GAP83116.1 - 3.2e-05 24.1 0.0 4.3e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 GAP83116.1 - 0.017 14.8 0.2 0.031 14.0 0.1 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain Integrin_beta PF00362.13 GAP83116.1 - 0.029 13.2 0.0 0.048 12.5 0.0 1.4 1 1 0 1 1 1 0 Integrin, beta chain PNP_UDP_1 PF01048.15 GAP83117.1 - 3.5e-07 29.4 0.3 9.6e-07 28.0 0.2 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_12 PF13424.1 GAP83118.1 - 2.8e-24 84.8 16.2 1.1e-07 31.7 0.0 7.3 5 2 1 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.1 GAP83118.1 - 1.6e-16 59.5 12.2 0.014 15.2 0.2 9.8 11 0 0 11 11 10 5 Tetratricopeptide repeat Apc3 PF12895.2 GAP83118.1 - 3.3e-14 52.7 11.4 0.0075 16.3 0.2 5.6 2 2 4 6 6 6 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 GAP83118.1 - 1.1e-12 47.3 11.0 0.00016 21.2 0.0 6.1 5 2 2 7 7 7 3 TPR repeat TPR_2 PF07719.12 GAP83118.1 - 1.6e-11 43.1 18.2 1 9.4 0.1 10.3 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAP83118.1 - 3.3e-11 43.3 5.9 1.1 9.6 0.0 7.2 5 3 2 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAP83118.1 - 2.1e-07 31.4 15.0 1.5 9.6 0.4 8.3 5 2 4 9 9 8 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAP83118.1 - 3.5e-07 29.5 16.6 3.1 7.5 0.1 9.8 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAP83118.1 - 8.1e-06 26.0 12.7 9.2 7.2 0.2 8.2 7 2 1 8 8 8 0 Tetratricopeptide repeat TPR_4 PF07721.9 GAP83118.1 - 1.8e-05 24.7 4.5 4.4 8.0 0.1 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAP83118.1 - 3.8e-05 23.1 7.0 0.33 10.8 0.1 6.4 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAP83118.1 - 7.5e-05 22.2 3.7 33 4.5 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat Apc5 PF12862.2 GAP83118.1 - 0.011 15.5 2.3 0.027 14.3 0.3 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_17 PF13431.1 GAP83118.1 - 0.048 13.8 4.4 32 5.0 0.1 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat PPR_1 PF12854.2 GAP83118.1 - 0.1 12.1 0.0 0.33 10.4 0.0 1.9 1 0 0 1 1 1 0 PPR repeat PPR PF01535.15 GAP83118.1 - 0.11 12.5 1.7 2.4 8.3 0.0 3.8 5 0 0 5 5 4 0 PPR repeat TPR_6 PF13174.1 GAP83118.1 - 5 7.7 15.7 85 3.9 0.0 8.0 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAP83119.1 - 4.6e-17 61.7 35.7 7.8e-05 22.5 0.2 10.9 7 4 6 13 13 13 5 Tetratricopeptide repeat TPR_11 PF13414.1 GAP83119.1 - 5.4e-15 54.7 27.0 0.00098 18.7 0.0 8.5 8 0 0 8 8 8 4 TPR repeat TPR_1 PF00515.23 GAP83119.1 - 1.1e-13 50.0 19.6 0.00052 19.5 0.0 10.6 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAP83119.1 - 1.2e-13 49.7 36.5 0.00031 20.4 0.0 12.1 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_16 PF13432.1 GAP83119.1 - 3.5e-12 46.6 22.9 0.06 14.0 0.0 9.9 9 3 1 10 10 9 4 Tetratricopeptide repeat Apc3 PF12895.2 GAP83119.1 - 1.9e-10 40.7 24.1 0.00019 21.5 0.5 7.7 4 2 2 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 GAP83119.1 - 1.9e-07 31.3 10.5 1.1 9.6 0.1 8.2 5 2 3 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAP83119.1 - 2.6e-07 29.9 13.5 0.0016 18.0 0.0 8.8 11 1 1 12 12 11 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAP83119.1 - 2.4e-06 26.9 4.7 0.54 10.1 0.0 6.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAP83119.1 - 6.1e-06 26.3 31.8 0.24 11.9 0.4 11.0 13 1 1 14 14 11 3 Tetratricopeptide repeat TPR_4 PF07721.9 GAP83119.1 - 0.00074 19.7 6.4 2 9.0 0.0 7.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAP83119.1 - 0.0076 16.3 8.2 53 4.3 0.0 7.4 6 1 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 GAP83119.1 - 0.0093 15.8 31.5 0.016 15.1 0.0 9.1 12 0 0 12 12 11 1 Tetratricopeptide repeat PPR PF01535.15 GAP83119.1 - 0.63 10.1 2.3 1.5e+02 2.7 0.0 4.7 4 0 0 4 4 4 0 PPR repeat DEAD PF00270.24 GAP83120.1 - 2e-31 108.7 0.1 2.6e-30 105.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP83120.1 - 5.3e-23 80.6 0.1 1.1e-22 79.6 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 GAP83120.1 - 0.00028 20.5 0.0 0.017 14.8 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain Helicase_C_2 PF13307.1 GAP83120.1 - 0.034 14.1 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain AAA_30 PF13604.1 GAP83120.1 - 0.036 13.6 0.0 0.15 11.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain NAD_binding_4 PF07993.7 GAP83120.1 - 0.095 11.6 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein CFEM PF05730.6 GAP83121.1 - 0.035 13.9 4.7 0.089 12.6 3.3 1.6 1 1 0 1 1 1 0 CFEM domain DUF2462 PF09495.5 GAP83122.1 - 1.1e-10 42.1 7.0 1.3e-10 41.7 4.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2462) CDK5_activator PF03261.10 GAP83122.1 - 0.018 14.4 0.1 0.02 14.2 0.1 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein PPR_2 PF13041.1 GAP83123.1 - 2.5e-15 56.1 0.0 1.7e-07 31.1 0.0 4.4 3 1 1 4 4 4 3 PPR repeat family PPR PF01535.15 GAP83123.1 - 4.6e-09 35.6 0.0 0.1 12.6 0.0 3.7 3 0 0 3 3 3 3 PPR repeat PPR_3 PF13812.1 GAP83123.1 - 4.6e-09 35.8 0.0 0.028 14.6 0.0 3.9 3 0 0 3 3 3 3 Pentatricopeptide repeat domain PPR_1 PF12854.2 GAP83123.1 - 6.7e-09 35.0 0.0 0.00062 19.1 0.0 4.3 4 0 0 4 4 4 3 PPR repeat cwf18 PF08315.7 GAP83124.1 - 1.1e-41 142.3 2.1 1.1e-41 142.3 1.5 1.5 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor SUZ PF12752.2 GAP83126.1 - 6.5e-14 52.1 1.6 6.5e-14 52.1 1.1 3.1 2 0 0 2 2 2 1 SUZ domain R3H PF01424.17 GAP83126.1 - 1e-07 31.4 0.0 2.6e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 R3H domain JAB PF01398.16 GAP83127.1 - 1.7e-17 63.2 0.0 2.8e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 GAP83127.1 - 1.4e-12 47.7 0.1 2.2e-12 47.0 0.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function DUF1253 PF06862.7 GAP83128.1 - 9.6e-148 492.2 0.0 1.3e-147 491.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DEAD PF00270.24 GAP83128.1 - 0.011 15.2 0.0 0.31 10.4 0.0 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase Corona_I PF03187.9 GAP83128.1 - 0.015 14.4 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Corona nucleocapsid I protein Ribosomal_L17 PF01196.14 GAP83129.1 - 1.7e-31 108.6 0.1 3.6e-31 107.5 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L17 Chol_subst-bind PF09129.6 GAP83129.1 - 0.041 13.0 0.0 0.044 12.9 0.0 1.1 1 0 0 1 1 1 0 Cholesterol oxidase, substrate-binding SR-25 PF10500.4 GAP83130.1 - 0.0045 16.4 3.2 0.0051 16.3 2.2 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF1490 PF07371.7 GAP83130.1 - 0.018 14.9 2.6 0.018 14.9 1.8 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1490) DUF639 PF04842.7 GAP83130.1 - 0.073 11.2 1.5 0.084 11.0 1.1 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) DUF4407 PF14362.1 GAP83130.1 - 1.9 7.3 11.0 3.6 6.4 7.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Zip PF02535.17 GAP83133.1 - 0.19 10.7 1.0 0.2 10.6 0.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter ABM PF03992.11 GAP83134.1 - 0.00016 21.5 0.1 0.00025 21.0 0.1 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase MFS_1 PF07690.11 GAP83135.1 - 1.5e-30 106.1 34.0 1.5e-30 106.1 23.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Choline_transpo PF04515.7 GAP83135.1 - 0.56 8.8 8.6 0.55 8.9 2.5 2.8 3 0 0 3 3 3 0 Plasma-membrane choline transporter ORMDL PF04061.9 GAP83137.1 - 1.8e-60 202.4 4.7 2.1e-60 202.1 3.2 1.0 1 0 0 1 1 1 1 ORMDL family U79_P34 PF03064.11 GAP83139.1 - 0.087 12.3 2.4 0.14 11.6 1.7 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RRN3 PF05327.6 GAP83139.1 - 0.16 10.0 0.1 0.19 9.7 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Adeno_terminal PF02459.10 GAP83139.1 - 7.7 4.5 6.9 11 4.0 4.8 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein UCH PF00443.24 GAP83140.1 - 5e-49 166.8 0.0 1e-48 165.7 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAP83140.1 - 1.3e-22 80.6 0.0 4.1e-22 78.9 0.0 1.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase SAE2 PF08573.5 GAP83141.1 - 1.8e-26 92.6 0.3 1.8e-26 92.6 0.2 2.4 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Kinesin-relat_1 PF12711.2 GAP83141.1 - 0.067 13.5 0.3 0.067 13.5 0.2 2.3 3 0 0 3 3 3 0 Kinesin motor Senescence PF06911.7 GAP83141.1 - 0.15 11.7 0.1 0.27 10.9 0.1 1.3 1 0 0 1 1 1 0 Senescence-associated protein BicD PF09730.4 GAP83141.1 - 0.82 7.9 8.7 3 6.0 6.0 1.8 1 1 0 1 1 1 0 Microtubule-associated protein Bicaudal-D ATG16 PF08614.6 GAP83141.1 - 1.3 8.7 9.4 4.8 6.9 6.5 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF342 PF03961.8 GAP83141.1 - 1.7 6.9 3.4 2.5 6.4 2.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) HOOK PF05622.7 GAP83141.1 - 2.2 5.9 10.6 0.26 9.0 0.4 2.1 2 0 0 2 2 2 0 HOOK protein BBP1_C PF15272.1 GAP83141.1 - 2.9 7.3 9.0 0.53 9.8 3.3 1.8 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal zf-CCHC PF00098.18 GAP83142.1 - 7.8e-51 167.7 64.7 1.1e-08 34.6 1.4 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 GAP83142.1 - 3e-11 42.7 46.0 0.031 13.9 0.6 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 GAP83142.1 - 4.2e-07 29.5 51.6 0.044 13.5 1.1 7.0 3 2 4 7 7 7 6 Zinc knuckle zf-CCHC_2 PF13696.1 GAP83142.1 - 0.0013 18.1 47.0 0.089 12.3 0.5 6.8 4 2 3 7 7 7 6 Zinc knuckle zf-CCHC_6 PF15288.1 GAP83142.1 - 0.31 10.7 49.2 0.4 10.3 0.5 6.7 5 2 2 7 7 7 0 Zinc knuckle RMF PF04957.7 GAP83142.1 - 9.8 5.9 18.8 0.27 10.9 0.9 4.5 3 2 2 5 5 5 0 Ribosome modulation factor DDHD PF02862.12 GAP83143.1 - 3e-73 246.3 2.3 1.2e-71 241.0 0.0 3.2 3 1 0 3 3 3 1 DDHD domain DUF2305 PF10230.4 GAP83143.1 - 0.022 14.2 0.1 0.092 12.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) RNA_pol_Rpb1_1 PF04997.7 GAP83144.1 - 3e-86 289.7 0.2 4.8e-86 289.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 GAP83144.1 - 1.3e-83 280.5 0.2 2.9e-83 279.3 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 GAP83144.1 - 5.3e-64 215.1 0.0 1.9e-63 213.3 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 GAP83144.1 - 3.6e-38 130.7 0.0 8.1e-38 129.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 GAP83144.1 - 1.7e-28 98.4 0.2 4.6e-28 97.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Mis14 PF08641.7 GAP83144.1 - 0.064 13.3 0.1 0.27 11.3 0.2 1.9 2 0 0 2 2 2 0 Kinetochore protein Mis14 like Mucin PF01456.12 GAP83145.1 - 0.17 11.6 18.1 0.032 14.0 9.8 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein Med3 PF11593.3 GAP83145.1 - 8.4 5.5 7.6 12 5.0 5.3 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MSP1_C PF07462.6 GAP83145.1 - 9.6 4.4 7.1 41 2.3 5.7 1.5 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus zf-C2H2 PF00096.21 GAP83146.1 - 8.8e-10 38.3 9.9 0.00014 21.9 0.9 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.13 GAP83146.1 - 6.3e-06 26.0 11.3 1.9e-05 24.4 7.9 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 GAP83146.1 - 3.4e-05 23.8 19.2 0.00056 20.0 0.9 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAP83146.1 - 0.0012 19.0 2.0 0.0012 19.0 1.4 4.5 4 1 0 4 4 4 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 GAP83146.1 - 0.0016 18.5 5.6 0.11 12.6 0.4 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAP83146.1 - 0.026 14.7 2.1 1.5 9.1 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.10 GAP83146.1 - 0.14 11.9 3.8 0.4 10.4 2.6 1.8 1 0 0 1 1 1 0 BED zinc finger adh_short PF00106.20 GAP83147.1 - 2.4e-32 112.1 1.3 3.2e-32 111.7 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP83147.1 - 6.4e-29 101.4 0.0 8.8e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP83147.1 - 5.3e-15 55.5 0.5 7.7e-15 55.0 0.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAP83147.1 - 0.00079 18.9 0.1 0.0013 18.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 GAP83147.1 - 0.023 14.7 0.1 0.042 13.9 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Peptidase_M17_N PF02789.12 GAP83147.1 - 0.09 12.5 1.6 0.15 11.7 1.1 1.3 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain Zn_clus PF00172.13 GAP83148.1 - 3.4e-06 26.8 7.8 6.5e-06 25.9 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.21 GAP83149.1 - 8.4e-73 244.9 0.0 1.9e-72 243.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAP83149.1 - 2.1e-43 148.8 0.0 1e-40 140.0 0.0 2.5 1 1 0 1 1 1 1 Acyl transferase domain Thioesterase PF00975.15 GAP83149.1 - 2.8e-43 148.7 0.0 2e-42 145.9 0.0 2.2 2 0 0 2 2 2 1 Thioesterase domain Ketoacyl-synt_C PF02801.17 GAP83149.1 - 1.7e-34 118.2 0.5 4.4e-34 116.8 0.4 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 GAP83149.1 - 1e-21 76.9 1.5 1.9e-10 40.8 0.2 3.2 3 0 0 3 3 3 2 Phosphopantetheine attachment site PS-DH PF14765.1 GAP83149.1 - 3.5e-12 46.1 0.0 7.2e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_5 PF12695.2 GAP83149.1 - 5.6e-08 32.6 0.2 0.0011 18.7 0.3 3.5 3 1 1 4 4 4 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP83149.1 - 5.5e-06 26.4 0.1 0.0024 17.7 0.0 2.9 3 0 0 3 3 3 1 Alpha/beta hydrolase family Thiolase_N PF00108.18 GAP83149.1 - 0.00022 20.2 0.1 0.00057 18.9 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Cu-oxidase_2 PF07731.9 GAP83150.1 - 7e-37 126.0 6.1 1.7e-34 118.3 0.2 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 GAP83150.1 - 6.5e-31 106.5 2.0 1.2e-29 102.4 0.4 3.2 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.17 GAP83150.1 - 1.4e-27 96.5 1.7 2.8e-24 85.8 0.1 3.1 3 0 0 3 3 3 2 Multicopper oxidase DUF92 PF01940.11 GAP83151.1 - 2.3e-62 210.0 4.3 3.1e-62 209.6 2.9 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Prenyltrans_1 PF13243.1 GAP83151.1 - 0.047 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Prenyltransferase-like Ras PF00071.17 GAP83152.1 - 1.8e-21 76.2 0.0 3.1e-21 75.4 0.0 1.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 GAP83152.1 - 8.6e-14 52.0 0.0 3.7e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAP83152.1 - 5.8e-05 22.3 0.0 0.00055 19.2 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family Arch_ATPase PF01637.13 GAP83152.1 - 0.065 12.9 0.2 0.13 11.9 0.1 1.6 1 1 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 GAP83152.1 - 0.078 13.2 0.3 0.37 11.0 0.2 2.0 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.15 GAP83152.1 - 0.081 11.6 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit SRPRB PF09439.5 GAP83152.1 - 0.088 12.0 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Mg_chelatase PF01078.16 GAP83152.1 - 0.098 11.8 0.2 0.29 10.2 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Septin PF00735.13 GAP83152.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_14 PF13173.1 GAP83152.1 - 0.15 11.9 0.1 0.25 11.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 GAP83152.1 - 0.2 11.5 2.4 0.95 9.4 1.7 2.1 1 1 0 1 1 1 0 AAA ATPase domain DUF3433 PF11915.3 GAP83153.1 - 9.3e-42 141.1 18.4 7e-25 87.0 0.5 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Pho86 PF11124.3 GAP83153.1 - 0.00082 18.4 0.8 0.034 13.1 0.1 2.3 2 0 0 2 2 2 2 Inorganic phosphate transporter Pho86 ICL PF00463.16 GAP83154.1 - 4.3e-277 919.4 0.1 4.9e-277 919.2 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 GAP83154.1 - 3.3e-12 46.1 1.4 7e-12 45.0 0.0 2.2 2 1 0 2 2 2 1 Phosphoenolpyruvate phosphomutase BTB PF00651.26 GAP83155.1 - 0.0068 16.3 0.0 0.025 14.5 0.0 1.8 2 1 1 3 3 3 1 BTB/POZ domain Trehalase PF01204.13 GAP83156.1 - 1.1e-189 631.4 0.1 1.3e-189 631.0 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 GAP83156.1 - 8.8e-18 63.3 1.4 1.4e-17 62.6 1.0 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Glyco_trans_2_3 PF13632.1 GAP83157.1 - 2.7e-45 154.4 1.4 2.7e-45 154.4 1.0 2.4 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAP83157.1 - 1.1e-08 35.1 0.0 2.7e-07 30.6 0.0 2.6 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 GAP83157.1 - 3.9e-05 23.3 0.0 0.00019 21.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 GAP83157.1 - 0.004 16.4 0.0 0.01 15.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 WD40 PF00400.27 GAP83158.1 - 1.7e-39 132.3 26.3 2.1e-09 36.9 0.4 10.7 11 0 0 11 11 11 6 WD domain, G-beta repeat Nup160 PF11715.3 GAP83158.1 - 0.014 13.5 0.3 0.037 12.1 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 PQQ_3 PF13570.1 GAP83158.1 - 0.02 15.1 17.1 2.8 8.3 0.0 7.5 7 1 0 7 7 7 0 PQQ-like domain DUF3639 PF12341.3 GAP83158.1 - 0.037 14.0 3.3 6.9 6.7 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3639) CPSF_A PF03178.10 GAP83158.1 - 0.081 12.0 0.0 5.2 6.0 0.0 3.1 3 1 0 3 3 3 0 CPSF A subunit region zf-CCHC PF00098.18 GAP83159.1 - 4.1e-59 193.8 119.8 1.2e-06 28.1 2.8 12.4 12 0 0 12 12 12 12 Zinc knuckle zf-CCHC_2 PF13696.1 GAP83159.1 - 1.5e-07 30.7 69.5 9e-05 21.8 0.6 11.6 5 4 6 11 11 11 9 Zinc knuckle zf-CCHC_3 PF13917.1 GAP83159.1 - 8e-06 25.4 94.8 0.0031 17.2 1.1 12.1 2 2 10 12 12 12 9 Zinc knuckle zf-CCHC_4 PF14392.1 GAP83159.1 - 1.7e-05 24.4 90.5 0.54 9.9 1.1 12.2 10 2 2 12 12 12 10 Zinc knuckle zf-CCHC_6 PF15288.1 GAP83159.1 - 5.2 6.8 94.9 0.37 10.4 0.4 12.1 8 3 4 12 12 12 0 Zinc knuckle Ribosomal_S28e PF01200.13 GAP83161.1 - 3.5e-33 113.1 3.2 3.8e-33 113.0 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e MFS_1 PF07690.11 GAP83162.1 - 1.1e-37 129.5 30.4 1.1e-37 129.5 21.1 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4381 PF14316.1 GAP83162.1 - 0.084 12.9 0.4 1.8 8.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) ATP-grasp_4 PF13535.1 GAP83163.1 - 8.1e-24 84.3 0.0 4.6e-16 59.0 0.0 3.8 3 1 1 4 4 4 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 GAP83163.1 - 3.6e-07 29.7 0.0 2.6e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 GAP83163.1 - 9.1e-07 27.9 0.0 0.00035 19.4 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.14 GAP83163.1 - 4.3e-06 26.4 0.0 7.1e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.9 GAP83163.1 - 6.3e-05 22.8 0.1 0.05 13.4 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp domain CPSase_L_D2 PF02786.12 GAP83163.1 - 0.00025 20.4 0.0 0.00097 18.4 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 GAP83163.1 - 0.018 14.5 0.0 0.042 13.3 0.0 1.6 1 0 0 1 1 1 0 RimK-like ATP-grasp domain AMP-binding PF00501.23 GAP83164.1 - 2.8e-57 193.9 0.0 3.3e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAP83164.1 - 2.9e-15 56.9 0.0 7.8e-15 55.5 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ICE2 PF08426.5 GAP83165.1 - 3.5e-138 460.6 11.7 4.1e-138 460.4 8.1 1.0 1 0 0 1 1 1 1 ICE2 Fungal_trans_2 PF11951.3 GAP83166.1 - 1e-06 27.6 0.2 1e-06 27.6 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain TauD PF02668.11 GAP83167.1 - 4.3e-53 180.6 0.0 5.4e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family SLAC1 PF03595.12 GAP83168.1 - 6.8e-85 284.6 35.9 7.8e-85 284.4 24.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel zf-CCHC_2 PF13696.1 GAP83169.1 - 0.056 12.9 0.7 0.12 11.9 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle CAF-1_p150 PF11600.3 GAP83169.1 - 0.27 10.5 24.2 0.57 9.5 16.8 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DDHD PF02862.12 GAP83169.1 - 0.47 10.2 2.9 0.8 9.4 2.0 1.4 1 0 0 1 1 1 0 DDHD domain DUF4337 PF14235.1 GAP83169.1 - 4.2 7.1 7.9 7.4 6.3 5.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF4407 PF14362.1 GAP83169.1 - 4.6 6.1 11.1 7.3 5.4 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.9 GAP83169.1 - 4.9 7.0 14.4 9.3 6.1 10.0 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ank_2 PF12796.2 GAP83170.1 - 4.9e-22 78.0 0.0 2.6e-06 27.6 0.0 4.7 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAP83170.1 - 4.8e-16 57.6 1.8 0.0028 17.3 0.0 6.8 6 1 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.1 GAP83170.1 - 3.3e-13 48.4 0.0 0.079 13.2 0.0 7.3 7 1 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.1 GAP83170.1 - 8.5e-11 42.0 0.0 0.034 14.6 0.0 6.0 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP83170.1 - 5.7e-10 39.1 0.4 0.058 13.6 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeats (many copies) TRAM_LAG1_CLN8 PF03798.11 GAP83171.1 - 1.5e-35 122.5 12.8 1.5e-35 122.5 8.9 2.2 3 0 0 3 3 3 1 TLC domain TRAM1 PF08390.6 GAP83171.1 - 1.4e-17 62.9 0.0 1.4e-17 62.9 0.0 1.8 2 0 0 2 2 2 1 TRAM1-like protein Cortexin PF11057.3 GAP83171.1 - 5.2 6.7 7.0 23 4.6 0.2 3.4 3 0 0 3 3 3 0 Cortexin of kidney PRELI PF04707.9 GAP83172.1 - 5.4e-19 68.3 0.0 7.5e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 PRELI-like family PalH PF08733.5 GAP83174.1 - 2.4 6.9 8.5 6.9 5.4 5.9 1.7 1 1 0 1 1 1 0 PalH/RIM21 G_glu_transpept PF01019.16 GAP83176.1 - 1.9e-138 462.1 0.0 2.2e-138 461.9 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase LysM PF01476.15 GAP83178.1 - 1.6e-17 63.0 0.4 7.4e-05 22.5 0.0 5.0 4 1 1 5 5 5 4 LysM domain UPF0203 PF05254.7 GAP83178.1 - 0.0046 16.7 0.5 11 6.0 0.0 3.7 3 1 0 3 3 3 2 Uncharacterised protein family (UPF0203) LysM PF01476.15 GAP83179.1 - 6.4e-13 48.3 0.1 2.3e-06 27.3 0.0 2.5 2 0 0 2 2 2 2 LysM domain Ank_2 PF12796.2 GAP83180.1 - 2.7e-26 91.7 0.0 1.6e-07 31.5 0.0 5.9 2 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAP83180.1 - 5e-24 84.2 1.9 3.9e-07 30.4 0.0 7.5 7 1 0 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.25 GAP83180.1 - 6.9e-23 79.2 12.9 4.4e-05 23.0 0.0 10.4 10 1 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.1 GAP83180.1 - 5.1e-16 58.3 5.6 0.0026 17.9 0.0 7.0 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP83180.1 - 2.7e-14 51.8 5.4 0.016 15.3 0.0 9.1 10 0 0 10 10 10 3 Ankyrin repeat PBP1_TM PF14812.1 GAP83182.1 - 0.06 13.6 2.0 0.14 12.5 1.4 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_hydro_7 PF00840.15 GAP83183.1 - 6.6e-176 584.9 15.3 7.8e-176 584.6 10.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF3680 PF12441.3 GAP83184.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3680) Beta_helix PF13229.1 GAP83185.1 - 2.2e-05 24.2 0.2 3.6e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.8 GAP83185.1 - 0.0018 17.4 0.1 0.0067 15.6 0.1 1.7 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Glutaredoxin PF00462.19 GAP83186.1 - 8e-14 51.3 0.0 1.4e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Flavoprotein PF02441.14 GAP83187.1 - 1.5e-40 137.8 0.0 2e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein zf-CCCH PF00642.19 GAP83188.1 - 0.00016 21.2 1.6 0.00029 20.4 1.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 GAP83188.1 - 0.031 14.2 3.6 0.067 13.2 2.5 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Sec1 PF00995.18 GAP83190.1 - 4.7e-149 497.6 0.0 5.5e-149 497.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Chitin_synth_1 PF01644.12 GAP83191.1 - 5.1e-81 270.2 0.4 7.7e-81 269.6 0.3 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 GAP83191.1 - 4e-33 112.9 0.1 7.8e-33 112.0 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 GAP83191.1 - 8.8e-22 77.1 0.8 6.5e-16 57.8 0.0 2.5 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 GAP83191.1 - 1.8e-08 34.5 0.0 9e-08 32.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 GAP83191.1 - 2.4e-08 33.8 8.9 2.4e-08 33.8 6.1 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 p450 PF00067.17 GAP83192.1 - 7.8e-71 238.9 0.0 9.7e-71 238.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Phage_lambda_P PF06992.6 GAP83192.1 - 0.0089 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Replication protein P Aconitase PF00330.15 GAP83193.1 - 5.4e-152 506.5 0.0 1.3e-151 505.2 0.0 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 GAP83193.1 - 1.5e-36 125.4 0.0 2.8e-36 124.5 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain FAD_binding_3 PF01494.14 GAP83195.1 - 5.7e-12 45.3 0.1 3.6e-11 42.7 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 GAP83195.1 - 8.3e-09 34.7 0.0 1.9e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAP83195.1 - 3.3e-08 32.8 4.4 3.6e-06 26.1 0.1 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAP83195.1 - 3e-07 30.3 0.0 9.1e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAP83195.1 - 3.6e-06 27.0 0.0 1.1e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAP83195.1 - 3.9e-06 25.6 0.0 1.5e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 GAP83195.1 - 8.1e-06 25.1 0.2 1.3e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAP83195.1 - 2.1e-05 24.8 0.1 0.00023 21.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAP83195.1 - 3.8e-05 22.7 0.0 6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 GAP83195.1 - 4.6e-05 22.5 0.1 0.00022 20.2 0.1 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 GAP83195.1 - 0.00038 19.2 0.1 0.2 10.2 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Thi4 PF01946.12 GAP83195.1 - 0.012 14.7 0.6 0.037 13.1 0.0 1.9 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.16 GAP83195.1 - 0.014 14.9 0.1 0.05 13.1 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 GAP83195.1 - 0.14 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.1 GAP83195.1 - 0.16 11.7 0.9 0.89 9.3 0.6 2.1 1 1 0 1 1 1 0 FAD-NAD(P)-binding MFS_1 PF07690.11 GAP83196.1 - 3.8e-34 117.9 23.9 3.8e-34 117.9 16.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sars6 PF12133.3 GAP83196.1 - 0.021 14.4 0.1 0.067 12.8 0.1 1.8 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus Actin PF00022.14 GAP83197.1 - 6.8e-133 442.8 0.0 7.7e-133 442.7 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 GAP83197.1 - 0.023 13.3 0.0 5.3 5.5 0.0 2.6 2 1 0 2 2 2 0 MreB/Mbl protein DUF3602 PF12223.3 GAP83198.1 - 3.9e-16 59.1 18.7 1.3e-11 44.7 2.1 2.8 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Pkinase PF00069.20 GAP83200.1 - 1.1e-05 24.7 0.0 1.8e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 GAP83200.1 - 0.0079 15.9 0.1 0.018 14.7 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Peptidase_C2 PF00648.16 GAP83201.1 - 3.1e-13 49.4 0.0 2.8e-07 29.8 0.0 2.1 2 0 0 2 2 2 2 Calpain family cysteine protease Acyl_transf_3 PF01757.17 GAP83202.1 - 2.2e-46 158.2 19.7 6.4e-46 156.7 13.7 1.7 1 1 0 1 1 1 1 Acyltransferase family BAF1_ABF1 PF04684.8 GAP83202.1 - 0.068 12.0 1.9 0.11 11.2 1.3 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Secretin_N_2 PF07655.8 GAP83202.1 - 0.7 10.3 10.0 1.6 9.1 7.0 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain Serglycin PF04360.7 GAP83202.1 - 1.7 8.3 4.2 3.3 7.4 2.9 1.4 1 0 0 1 1 1 0 Serglycin Peptidase_S9 PF00326.16 GAP83203.1 - 3.1e-45 154.0 0.5 5.1e-45 153.3 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAP83203.1 - 2.1e-06 27.5 0.1 4.7e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 GAP83203.1 - 0.0007 19.1 1.3 0.058 13.0 0.0 3.7 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Arylesterase PF01731.15 GAP83203.1 - 0.065 13.2 0.4 6.2 6.8 0.0 4.0 5 0 0 5 5 5 0 Arylesterase WD40 PF00400.27 GAP83204.1 - 2e-35 119.3 0.6 2.7e-10 39.7 0.0 6.1 5 1 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 GAP83204.1 - 0.00097 18.8 0.1 0.31 10.7 0.0 3.0 2 2 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 GAP83204.1 - 0.0023 17.3 0.5 0.012 14.9 0.2 1.8 1 1 1 2 2 2 1 Lipoprotein LpqB beta-propeller domain Coatomer_WDAD PF04053.9 GAP83204.1 - 0.0066 15.2 0.0 0.015 14.1 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region Nup160 PF11715.3 GAP83204.1 - 0.019 13.1 0.1 0.042 11.9 0.0 1.4 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAP83204.1 - 0.038 12.7 0.0 0.24 10.0 0.0 2.0 1 1 0 1 1 1 0 Nup133 N terminal like SdiA-regulated PF06977.6 GAP83204.1 - 0.066 12.1 0.0 0.84 8.5 0.0 2.2 2 0 0 2 2 2 0 SdiA-regulated FTHFS PF01268.14 GAP83205.1 - 1.2e-255 848.7 0.2 1.6e-255 848.3 0.1 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 GAP83205.1 - 4.5e-69 230.6 2.0 8.4e-69 229.7 0.3 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 GAP83205.1 - 9e-36 122.4 1.1 2e-35 121.3 0.7 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DUF4588 PF15251.1 GAP83206.1 - 1e-06 28.9 0.5 1e-06 28.9 0.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) SNF2_N PF00176.18 GAP83207.1 - 5.7e-81 271.5 0.0 9.3e-81 270.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 GAP83207.1 - 2.4e-42 143.4 2.6 4.9e-42 142.4 1.1 2.2 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 GAP83207.1 - 1.3e-33 115.7 2.7 1.3e-33 115.7 1.8 3.5 4 0 0 4 4 4 1 HAND Helicase_C PF00271.26 GAP83207.1 - 2.3e-15 56.2 0.1 3.9e-14 52.2 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAP83207.1 - 2.7e-09 37.1 0.1 3.1e-08 33.6 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 GAP83207.1 - 3.2e-07 29.4 0.0 7.9e-07 28.1 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 GAP83207.1 - 0.00013 21.5 0.0 0.00029 20.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.26 GAP83207.1 - 0.00063 19.7 0.0 0.19 11.8 0.0 3.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain AAA_22 PF13401.1 GAP83207.1 - 0.087 12.9 0.0 1.4 9.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain ALAD PF00490.16 GAP83208.1 - 2.9e-116 387.8 0.0 4.2e-116 387.3 0.0 1.2 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Avl9 PF09794.4 GAP83209.1 - 0.026 13.0 0.0 0.037 12.5 0.0 1.1 1 0 0 1 1 1 0 Transport protein Avl9 APH PF01636.18 GAP83209.1 - 0.045 13.4 0.1 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 GAP83209.1 - 0.052 12.8 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family MFS_1 PF07690.11 GAP83210.1 - 3.4e-14 52.3 54.1 3.4e-14 52.3 37.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Y_phosphatase3 PF13350.1 GAP83211.1 - 1.7e-36 125.9 0.0 2.1e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 GAP83211.1 - 8.8e-09 35.3 0.0 2.5e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 GAP83211.1 - 0.00086 18.7 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 GAP83211.1 - 0.0044 16.3 0.0 0.0062 15.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 GAP83211.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Amidohydro_3 PF07969.6 GAP83212.1 - 2.1e-57 195.2 2.6 2.6e-57 194.8 1.8 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 GAP83212.1 - 0.0014 18.3 0.0 0.016 14.8 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 GAP83212.1 - 0.0051 16.8 7.0 0.51 10.3 0.1 2.9 3 0 0 3 3 3 2 Amidohydrolase Amidohydro_5 PF13594.1 GAP83212.1 - 0.0062 16.3 0.0 0.027 14.2 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase PPR_2 PF13041.1 GAP83213.1 - 3e-08 33.5 0.0 1.1 9.3 0.0 5.6 5 1 1 6 6 6 3 PPR repeat family PPR_3 PF13812.1 GAP83213.1 - 5.3e-07 29.4 0.2 0.006 16.7 0.1 6.1 7 0 0 7 7 7 1 Pentatricopeptide repeat domain PPR PF01535.15 GAP83213.1 - 0.0012 18.6 0.9 2.9 8.0 0.0 5.2 5 0 0 5 5 5 1 PPR repeat UBA_2 PF08587.6 GAP83213.1 - 0.037 14.2 0.2 6.9 6.9 0.0 3.2 4 0 0 4 4 4 0 Ubiquitin associated domain (UBA) Ribosomal_S18 PF01084.15 GAP83214.1 - 1.6e-11 43.8 0.0 3.3e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 M_domain PF12938.2 GAP83214.1 - 0.038 13.7 7.0 0.054 13.3 4.9 1.2 1 0 0 1 1 1 0 M domain of GW182 Mito_fiss_reg PF05308.6 GAP83214.1 - 0.95 8.7 7.2 1.6 8.0 5.0 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 GAP83214.1 - 2.8 7.1 7.6 4.2 6.5 5.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal S4 PF01479.20 GAP83215.1 - 3.2e-11 42.4 0.0 6.2e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 S4 domain HORMA PF02301.13 GAP83217.1 - 3.1e-45 154.2 0.0 3.7e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 HORMA domain MSA-2c PF12238.3 GAP83217.1 - 0.012 15.2 0.4 0.017 14.7 0.3 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c UCH PF00443.24 GAP83218.1 - 2.1e-40 138.5 0.0 3.7e-40 137.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 GAP83218.1 - 8e-23 80.3 15.9 2.9e-18 65.7 1.9 3.0 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 GAP83218.1 - 6.7e-22 76.7 0.2 5.9e-10 38.6 0.0 2.7 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.1 GAP83218.1 - 1.3e-18 67.5 0.0 4.8e-18 65.6 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.1 GAP83218.1 - 0.0084 15.6 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Prenyltrans_1 PF13243.1 GAP83218.1 - 0.11 12.4 0.0 1.8 8.5 0.0 2.5 2 0 0 2 2 2 0 Prenyltransferase-like NifU_N PF01592.11 GAP83219.1 - 4.1e-52 175.4 0.0 5.1e-52 175.1 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain DEAD PF00270.24 GAP83220.1 - 4.9e-50 169.3 0.1 3.1e-47 160.1 0.0 2.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP83220.1 - 1.6e-29 101.5 0.0 2.5e-28 97.7 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 GAP83220.1 - 0.0039 15.6 0.0 0.0039 15.6 0.0 3.0 3 1 0 3 3 3 1 Protein of unknown function (DUF1253) MIP-T3 PF10243.4 GAP83220.1 - 0.0056 15.2 31.8 0.0074 14.8 22.0 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CMS1 PF14617.1 GAP83220.1 - 0.0058 15.7 0.0 0.0058 15.7 0.0 4.2 2 1 2 4 4 4 1 U3-containing 90S pre-ribosomal complex subunit SOBP PF15279.1 GAP83220.1 - 0.0072 16.7 8.2 0.011 16.1 5.7 1.2 1 0 0 1 1 1 1 Sine oculis-binding protein TFIIF_alpha PF05793.7 GAP83220.1 - 1.7 6.9 37.6 2.9 6.1 26.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Rft-1 PF04506.8 GAP83221.1 - 5.5e-89 298.9 0.1 6.7e-89 298.7 0.1 1.0 1 0 0 1 1 1 1 Rft protein GMC_oxred_N PF00732.14 GAP83222.1 - 2.9e-53 180.9 0.0 3.9e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAP83222.1 - 1.6e-38 132.2 0.0 2.6e-38 131.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAP83222.1 - 4e-07 29.2 0.2 0.0011 17.9 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAP83222.1 - 0.00055 18.9 1.5 0.00065 18.7 0.4 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAP83222.1 - 0.0021 17.9 0.2 0.0051 16.7 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP83222.1 - 0.0027 17.6 1.3 0.0061 16.5 0.9 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAP83222.1 - 0.0028 16.7 0.1 0.074 12.1 0.1 2.2 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 GAP83222.1 - 0.0064 15.4 0.1 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 GAP83222.1 - 0.02 14.9 0.8 0.13 12.3 0.3 2.4 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAP83222.1 - 0.04 13.6 0.1 0.096 12.4 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 GAP83222.1 - 0.054 12.1 0.3 0.083 11.5 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Sugar_tr PF00083.19 GAP83223.1 - 4.7e-122 407.8 19.6 5.3e-122 407.6 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP83223.1 - 1.3e-26 93.1 27.9 1.5e-17 63.3 6.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.4 GAP83223.1 - 3.4 7.7 7.2 9.9 6.2 1.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) HgmA PF04209.8 GAP83224.1 - 3.6e-13 48.7 0.1 3.9e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase RPE65 PF03055.10 GAP83225.1 - 5.1e-112 374.9 0.0 5.8e-112 374.7 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Lipase_GDSL PF00657.17 GAP83226.1 - 3.3e-06 27.1 0.1 5.8e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 GAP83226.1 - 0.00066 19.8 0.0 0.0013 18.8 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family MIT PF04212.13 GAP83227.1 - 1.1e-11 44.3 0.5 2.2e-11 43.4 0.4 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TIM PF00121.13 GAP83228.1 - 7.4e-40 136.5 0.0 1.3e-39 135.7 0.0 1.4 1 1 0 1 1 1 1 Triosephosphate isomerase LacAB_rpiB PF02502.13 GAP83229.1 - 1.4e-38 131.7 0.6 1.6e-38 131.5 0.4 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Dak1 PF02733.12 GAP83230.1 - 2.4e-105 351.7 0.1 3.1e-105 351.3 0.1 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 GAP83230.1 - 1e-36 126.2 2.2 1.8e-36 125.4 1.5 1.5 1 0 0 1 1 1 1 DAK2 domain F_bP_aldolase PF01116.15 GAP83231.1 - 2.6e-82 276.1 0.3 2.9e-82 275.9 0.2 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II NAD_binding_2 PF03446.10 GAP83232.1 - 7.7e-37 126.6 0.0 1.2e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 GAP83232.1 - 9.1e-32 109.6 0.0 5.3e-22 78.1 0.0 2.4 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 GAP83232.1 - 1.9e-06 28.1 0.0 7.1e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 GAP83232.1 - 5.8e-06 26.0 0.9 0.00031 20.4 0.0 2.9 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 GAP83232.1 - 0.00041 19.8 0.0 0.00069 19.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 GAP83232.1 - 0.052 12.6 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 GAP83232.1 - 0.081 12.3 0.0 0.19 11.0 0.0 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain zf-UBR PF02207.15 GAP83233.1 - 4.8e-16 58.2 2.4 4.8e-16 58.2 1.7 2.6 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) MCM PF00493.18 GAP83234.1 - 1e-139 464.9 0.1 1.5e-139 464.4 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 GAP83234.1 - 7e-34 117.0 33.9 7e-34 117.0 23.5 2.5 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 GAP83234.1 - 1.9e-21 76.8 0.1 4.7e-21 75.5 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 GAP83234.1 - 9e-08 31.5 0.0 6e-06 25.5 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 GAP83234.1 - 2.2e-06 27.4 0.0 4.7e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 GAP83234.1 - 0.00055 19.5 0.1 0.018 14.6 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 GAP83234.1 - 0.0013 18.1 0.2 0.0094 15.4 0.2 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain DUF3113 PF11310.3 GAP83234.1 - 0.029 14.0 0.2 1.7 8.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3113) zf-TFIIB PF13453.1 GAP83234.1 - 0.041 13.0 1.2 0.087 12.0 0.8 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger Zn_ribbon_2 PF12674.2 GAP83234.1 - 0.068 13.5 0.5 0.26 11.6 0.4 2.0 1 0 0 1 1 1 0 Putative zinc ribbon domain AA_permease PF00324.16 GAP83235.1 - 9.4e-79 264.9 40.1 1.1e-78 264.6 27.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAP83235.1 - 2.1e-33 115.5 41.2 2.6e-33 115.2 28.6 1.1 1 0 0 1 1 1 1 Amino acid permease Phage_lysis PF03245.8 GAP83236.1 - 0.12 12.3 2.0 0.19 11.7 0.3 2.2 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein Glyco_hydro_2_N PF02837.13 GAP83237.1 - 1.7e-27 96.0 0.2 8e-27 93.8 0.2 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 GAP83237.1 - 4.3e-12 46.4 0.1 9.6e-12 45.3 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 GAP83237.1 - 1.2e-11 44.0 0.5 2.2e-11 43.1 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain NAD_binding_10 PF13460.1 GAP83239.1 - 3e-07 30.6 2.7 3.7e-07 30.3 1.9 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAP83239.1 - 2e-06 27.4 0.3 2.4e-06 27.1 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 GAP83239.1 - 7.3e-05 22.7 0.2 9.9e-05 22.3 0.2 1.2 1 0 0 1 1 1 1 TrkA-N domain NmrA PF05368.8 GAP83239.1 - 0.0003 20.1 0.3 0.00037 19.8 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 GAP83239.1 - 0.00074 18.5 0.2 0.00094 18.2 0.2 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase ApbA PF02558.11 GAP83239.1 - 0.0034 16.8 0.2 0.0048 16.3 0.2 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3Beta_HSD PF01073.14 GAP83239.1 - 0.011 14.3 0.0 0.016 13.9 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 2-Hacid_dh_C PF02826.14 GAP83239.1 - 0.056 12.6 0.0 0.077 12.1 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 GAP83239.1 - 0.079 13.3 0.3 0.12 12.7 0.2 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 GAP83239.1 - 0.087 12.6 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 GAP83239.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 GAP83239.1 - 0.16 11.3 0.1 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF605 PF04652.11 GAP83241.1 - 0.48 9.7 7.0 0.56 9.5 4.8 1.1 1 0 0 1 1 1 0 Vta1 like Glyco_hydro_76 PF03663.9 GAP83242.1 - 1.4e-115 386.5 11.2 1.7e-115 386.3 7.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 His_Phos_1 PF00300.17 GAP83243.1 - 7.6e-20 71.5 0.0 9.5e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CTNNBL PF08216.6 GAP83244.1 - 4.3e-31 106.6 0.0 2.4e-30 104.2 0.0 2.4 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Sugar_tr PF00083.19 GAP83246.1 - 4e-74 249.8 23.4 4.6e-74 249.6 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP83246.1 - 4.2e-13 48.7 29.7 3e-11 42.6 14.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 GAP83247.1 - 2.3e-08 33.0 0.6 2.3e-08 33.0 0.4 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP83247.1 - 1.8e-07 30.9 9.4 3.4e-07 30.0 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF706 PF05153.10 GAP83248.1 - 8e-129 428.3 1.0 1e-128 427.9 0.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 GAP83248.1 - 0.03 14.3 0.0 0.52 10.3 0.0 2.3 2 0 0 2 2 2 0 HD domain DUF2270 PF10028.4 GAP83248.1 - 0.14 11.6 0.1 0.22 11.0 0.1 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2270) DUF1996 PF09362.5 GAP83249.1 - 3.2e-86 288.8 0.9 4.2e-86 288.4 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 GAP83249.1 - 4.4e-19 68.1 3.8 1.4e-18 66.5 2.6 1.9 1 0 0 1 1 1 1 WSC domain DUF2828 PF11443.3 GAP83250.1 - 8.8e-173 575.3 0.0 1.1e-172 575.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) zf-CCHC PF00098.18 GAP83252.1 - 1.7e-44 147.7 56.4 1.9e-07 30.6 1.3 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 GAP83252.1 - 1.3e-09 37.5 42.8 0.073 12.7 0.7 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 GAP83252.1 - 4.8e-06 26.2 43.6 0.13 12.0 0.6 6.9 4 2 2 6 6 6 4 Zinc knuckle zf-CCHC_2 PF13696.1 GAP83252.1 - 0.048 13.1 0.2 0.048 13.1 0.2 7.1 4 2 3 7 7 7 0 Zinc knuckle zf-CCHC_6 PF15288.1 GAP83252.1 - 0.09 12.4 0.5 0.09 12.4 0.3 7.1 6 1 1 7 7 7 0 Zinc knuckle WD40 PF00400.27 GAP83254.1 - 4.8e-50 165.7 10.4 3.2e-09 36.3 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 GAP83254.1 - 7.8e-06 24.8 4.4 0.042 12.6 0.7 3.4 1 1 0 2 2 2 2 Nup133 N terminal like TRAPP PF04051.11 GAP83255.1 - 1.8e-36 124.9 0.1 2.1e-36 124.7 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF4250 PF14056.1 GAP83255.1 - 0.12 12.1 0.1 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) LisH PF08513.6 GAP83256.1 - 0.076 12.8 0.2 0.13 12.0 0.2 1.4 1 0 0 1 1 1 0 LisH MFS_1 PF07690.11 GAP83257.1 - 3.5e-18 65.4 32.5 2.5e-12 46.2 14.3 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP83257.1 - 0.017 13.6 13.2 0.45 9.0 1.7 3.1 2 1 0 2 2 2 0 Sugar (and other) transporter MFS_1 PF07690.11 GAP83258.1 - 7.2e-26 90.7 48.7 1.2e-24 86.7 26.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAP83258.1 - 7.3e-05 21.1 4.7 0.00013 20.3 3.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1228 PF06779.9 GAP83258.1 - 0.013 15.4 3.0 0.036 14.0 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) COesterase PF00135.23 GAP83259.1 - 3.9e-85 286.5 0.0 5e-85 286.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAP83259.1 - 3.9e-11 42.9 0.1 1.9e-10 40.7 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 GAP83259.1 - 0.00076 18.4 0.0 0.0014 17.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.2 GAP83259.1 - 0.002 17.8 0.2 0.0042 16.8 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 GAP83259.1 - 0.0023 16.8 0.0 0.0039 16.0 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase DUF2424 PF10340.4 GAP83259.1 - 0.15 10.6 0.1 6 5.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) CitMHS PF03600.11 GAP83260.1 - 1.7 7.1 8.0 1.8 7.0 5.5 1.0 1 0 0 1 1 1 0 Citrate transporter Transaldolase PF00923.14 GAP83261.1 - 4e-24 85.2 0.0 5.4e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Transaldolase Pkinase PF00069.20 GAP83263.1 - 4.2e-57 193.2 0.0 6.6e-57 192.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP83263.1 - 4.3e-20 71.8 0.0 6.7e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAP83263.1 - 0.038 13.7 0.0 0.1 12.2 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAP83263.1 - 0.095 12.2 0.6 0.2 11.2 0.4 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Mpp10 PF04006.7 GAP83264.1 - 1.6e-96 324.0 69.0 3.4e-95 319.6 47.8 2.2 1 1 0 1 1 1 1 Mpp10 protein Adap_comp_sub PF00928.16 GAP83265.1 - 4.1e-60 203.0 0.0 3.7e-59 199.9 0.0 1.9 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 GAP83265.1 - 0.0001 22.0 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Acyl_transf_1 PF00698.16 GAP83266.1 - 5e-23 81.9 0.2 6.6e-17 61.8 0.1 2.1 1 1 1 2 2 2 2 Acyl transferase domain Sedlin_N PF04628.8 GAP83267.1 - 1.9e-18 66.5 0.0 2.5e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 GAP83267.1 - 0.15 11.7 0.0 2.9 7.6 0.0 2.1 2 0 0 2 2 2 0 Sybindin-like family Ribosomal_60s PF00428.14 GAP83267.1 - 0.18 12.2 3.4 0.11 12.8 1.2 1.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein AFG1_ATPase PF03969.11 GAP83268.1 - 1.8e-33 115.8 0.1 3e-16 59.2 0.0 4.1 4 0 0 4 4 4 4 AFG1-like ATPase Bac_DnaA PF00308.13 GAP83268.1 - 0.064 12.8 0.0 2.6 7.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial dnaA protein Nucleoporin_C PF03177.9 GAP83269.1 - 2.7e-76 257.3 11.8 4.3e-76 256.6 8.2 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 GAP83269.1 - 1.4e-65 221.7 0.0 2e-65 221.1 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Acetyltransf_1 PF00583.19 GAP83270.1 - 4e-13 49.1 0.5 6.2e-13 48.5 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAP83270.1 - 4.3e-10 39.7 2.1 4.4e-09 36.4 1.5 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAP83270.1 - 8.8e-08 32.2 0.0 1.8e-07 31.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAP83270.1 - 2.3e-07 30.4 0.1 5.1e-07 29.3 0.0 1.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.1 GAP83270.1 - 6e-06 26.1 0.2 0.0053 16.6 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAP83270.1 - 0.01 15.7 0.2 0.021 14.7 0.1 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Aldolase_II PF00596.16 GAP83272.1 - 5.2e-47 159.8 0.8 7.2e-47 159.3 0.6 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain TetR_N PF00440.18 GAP83272.1 - 0.038 13.6 1.5 0.67 9.6 0.0 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Fungal_trans_2 PF11951.3 GAP83273.1 - 0.0032 16.1 0.2 0.0078 14.8 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Arrestin_N PF00339.24 GAP83275.1 - 2.2e-16 60.0 0.0 7e-10 38.9 0.0 3.3 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain SRC-1 PF08832.5 GAP83275.1 - 0.17 12.6 0.0 0.37 11.5 0.0 1.6 1 0 0 1 1 1 0 Steroid receptor coactivator Iso_dh PF00180.15 GAP83276.1 - 5.9e-72 242.5 0.0 6.9e-72 242.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF2543 PF10820.3 GAP83276.1 - 0.14 12.2 0.3 0.36 10.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2543) AhpC-TSA PF00578.16 GAP83277.1 - 1.7e-23 82.6 0.0 2.6e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 GAP83277.1 - 2.5e-13 49.8 0.1 3.1e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 GAP83277.1 - 0.022 14.6 0.0 0.055 13.4 0.0 1.6 1 1 0 1 1 1 0 AhpC/TSA antioxidant enzyme DUF2360 PF10152.4 GAP83277.1 - 9.3 6.5 8.4 4.5 7.5 2.5 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) zf-C3HC4_4 PF15227.1 GAP83278.1 - 0.15 11.9 3.2 0.12 12.2 0.7 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING HypA PF01155.14 GAP83278.1 - 0.23 11.1 1.9 0.51 10.0 1.3 1.5 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Prok-RING_1 PF14446.1 GAP83278.1 - 0.86 9.3 6.5 0.083 12.6 0.7 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF1680 PF07944.7 GAP83281.1 - 2.1e-112 376.0 0.1 2.7e-112 375.7 0.1 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Not3 PF04065.10 GAP83282.1 - 3.4e-100 334.1 20.1 6.8e-100 333.1 13.9 1.5 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 GAP83282.1 - 7.3e-41 139.2 11.0 7.3e-41 139.2 7.6 1.8 2 0 0 2 2 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.4 GAP83282.1 - 0.0056 16.1 3.6 0.013 15.0 2.5 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) DUF1192 PF06698.6 GAP83282.1 - 0.0083 15.9 3.7 0.0083 15.9 2.5 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1192) Syntaxin PF00804.20 GAP83282.1 - 0.02 15.0 13.2 0.042 14.0 4.1 2.7 2 0 0 2 2 2 0 Syntaxin Sec5 PF15469.1 GAP83282.1 - 0.024 14.3 9.6 0.33 10.6 0.8 2.6 3 0 0 3 3 3 0 Exocyst complex component Sec5 Cep57_MT_bd PF06657.8 GAP83282.1 - 0.046 13.6 8.3 0.16 11.9 0.3 3.2 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Snapin_Pallidin PF14712.1 GAP83282.1 - 0.058 13.7 0.5 0.058 13.7 0.3 3.0 3 0 0 3 3 3 0 Snapin/Pallidin Poty_PP PF08440.5 GAP83282.1 - 0.22 10.5 4.4 0.16 10.9 0.6 2.2 2 0 0 2 2 2 0 Potyviridae polyprotein Syntaxin_2 PF14523.1 GAP83282.1 - 0.35 10.9 9.5 0.029 14.4 2.0 2.6 3 0 0 3 3 2 0 Syntaxin-like protein DUF664 PF04978.7 GAP83282.1 - 0.97 9.6 5.1 0.22 11.7 0.9 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF664) DUF241 PF03087.9 GAP83282.1 - 1.6 8.1 8.5 4 6.8 5.9 1.7 1 0 0 1 1 1 0 Arabidopsis protein of unknown function MerR-DNA-bind PF09278.6 GAP83282.1 - 4 7.9 13.8 2.7 8.4 1.4 3.3 2 1 1 3 3 3 0 MerR, DNA binding Tyr_Deacylase PF02580.11 GAP83283.1 - 1.2e-45 155.0 0.5 1.4e-45 154.8 0.3 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DUF4369 PF14289.1 GAP83283.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4369) Yippee-Mis18 PF03226.9 GAP83284.1 - 4.6e-18 65.0 0.0 6.6e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 GAP83284.1 - 0.00058 19.7 1.0 0.0061 16.4 0.3 2.0 2 0 0 2 2 2 1 C-terminal domain of RIG-I Marek_A PF02124.10 GAP83284.1 - 0.016 14.6 0.1 0.026 13.9 0.1 1.4 1 0 0 1 1 1 0 Marek's disease glycoprotein A RRN7 PF11781.3 GAP83284.1 - 0.096 12.2 4.4 0.8 9.2 0.9 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 DNA_RNApol_7kD PF03604.8 GAP83284.1 - 1.9 7.9 4.2 3 7.4 0.1 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Peptidase_M48 PF01435.13 GAP83287.1 - 5e-40 137.4 0.0 6.5e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 SpecificRecomb PF10136.4 GAP83287.1 - 0.027 12.5 0.6 0.04 11.9 0.4 1.1 1 0 0 1 1 1 0 Site-specific recombinase Ank_2 PF12796.2 GAP83288.1 - 2.4e-97 319.4 19.1 1.8e-20 73.0 0.4 6.7 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 GAP83288.1 - 2e-89 289.2 26.1 1.1e-09 37.5 0.1 12.4 12 0 0 12 12 12 11 Ankyrin repeat Ank_5 PF13857.1 GAP83288.1 - 9.5e-72 235.4 23.3 1.1e-13 50.9 0.2 11.0 3 2 8 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP83288.1 - 3.1e-64 206.4 19.9 7.8e-07 28.7 0.0 12.6 13 0 0 13 13 13 11 Ankyrin repeat Ank_4 PF13637.1 GAP83288.1 - 1.9e-59 197.0 16.9 4e-10 39.9 0.1 10.4 3 3 9 12 12 12 9 Ankyrin repeats (many copies) GATase_7 PF13537.1 GAP83288.1 - 0.0072 16.0 1.6 12 5.6 0.0 4.6 5 1 1 6 6 6 1 Glutamine amidotransferase domain Shigella_OspC PF06128.6 GAP83288.1 - 0.027 13.9 3.7 18 4.6 0.0 5.0 1 1 4 5 5 5 0 Shigella flexneri OspC protein Zn_clus PF00172.13 GAP83288.1 - 0.25 11.2 8.1 0.43 10.5 5.6 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyt-b5 PF00173.23 GAP83289.1 - 4.5e-18 64.8 0.1 5e-18 64.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.3 GAP83289.1 - 0.011 15.6 0.0 0.088 12.7 0.0 2.0 1 1 1 2 2 2 0 V-ATPase subunit H BRX PF08381.6 GAP83289.1 - 0.039 13.0 0.4 0.13 11.3 0.3 1.9 1 1 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 TPP_enzyme_C PF02775.16 GAP83289.1 - 0.088 12.3 0.0 0.091 12.3 0.0 1.1 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain EFP_N PF08207.7 GAP83289.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain dCMP_cyt_deam_1 PF00383.17 GAP83290.1 - 3.5e-25 87.6 2.0 4.6e-25 87.2 1.4 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region ThiF PF00899.16 GAP83291.1 - 7.8e-27 93.7 0.0 2e-26 92.4 0.0 1.7 2 0 0 2 2 2 1 ThiF family Shikimate_DH PF01488.15 GAP83291.1 - 0.04 14.0 0.0 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.11 GAP83293.1 - 6.1e-35 120.5 57.0 1.1e-29 103.3 25.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP83293.1 - 1.3e-21 76.7 19.8 2.7e-17 62.4 3.7 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter DnaJ PF00226.26 GAP83294.1 - 4.3e-07 29.5 0.0 7.3e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain K_channel_TID PF07941.6 GAP83294.1 - 4.5 7.5 7.4 0.67 10.2 0.3 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain GSK-3_bind PF05350.7 GAP83295.1 - 7.1e-05 22.3 1.1 0.075 12.4 0.1 2.3 2 0 0 2 2 2 2 Glycogen synthase kinase-3 binding F-box PF00646.28 GAP83295.1 - 0.0015 18.1 0.1 0.0055 16.3 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 GAP83295.1 - 0.002 17.8 2.4 0.06 13.0 0.1 2.9 2 0 0 2 2 2 1 F-box-like FA_desaturase PF00487.19 GAP83296.1 - 4.6e-32 111.4 18.4 6.3e-32 111.0 12.8 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 GAP83296.1 - 1.2e-19 69.2 0.4 2.2e-19 68.3 0.2 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Motile_Sperm PF00635.21 GAP83297.1 - 1.6e-24 85.6 0.2 3.6e-24 84.5 0.1 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF756 PF05506.7 GAP83297.1 - 0.024 15.1 0.0 0.059 13.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF756) FixG_C PF11614.3 GAP83297.1 - 0.071 13.2 0.5 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase DUF4148 PF13663.1 GAP83297.1 - 0.097 12.5 1.6 2.4 8.1 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Ycf9 PF01737.12 GAP83297.1 - 1.3 8.5 6.3 7.2 6.1 0.0 2.7 3 0 0 3 3 3 0 YCF9 UBX PF00789.15 GAP83298.1 - 0.0021 18.0 0.0 0.0069 16.4 0.0 1.9 2 0 0 2 2 2 1 UBX domain UBA PF00627.26 GAP83298.1 - 0.0033 17.2 0.1 0.0095 15.7 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain zf-C2H2_2 PF12756.2 GAP83298.1 - 0.045 13.8 0.8 0.091 12.8 0.1 1.8 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) GATA PF00320.22 GAP83298.1 - 0.072 12.4 0.1 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 GATA zinc finger zf-C2H2 PF00096.21 GAP83298.1 - 0.12 12.8 0.5 0.21 12.0 0.4 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type SOBP PF15279.1 GAP83298.1 - 0.27 11.5 3.7 0.3 11.4 2.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein CAF-1_p150 PF11600.3 GAP83298.1 - 0.29 10.5 38.9 0.4 10.0 27.0 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PLRV_ORF5 PF01690.12 GAP83298.1 - 0.78 8.8 13.7 0.96 8.5 9.5 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Adeno_PVIII PF01310.13 GAP83298.1 - 1.2 8.8 6.7 2.1 8.1 4.2 1.6 1 1 0 1 1 1 0 Adenovirus hexon associated protein, protein VIII DUF342 PF03961.8 GAP83298.1 - 1.7 7.0 18.4 2.4 6.4 12.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Neur_chan_memb PF02932.11 GAP83298.1 - 3.7 7.3 5.4 4.9 6.9 3.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ribosomal_60s PF00428.14 GAP83299.1 - 7.4e-26 90.3 8.6 1e-25 89.9 5.9 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2408 PF10303.4 GAP83300.1 - 4.5e-47 159.5 1.4 1.1e-27 96.8 0.0 5.0 3 2 2 5 5 5 3 Protein of unknown function (DUF2408) MitMem_reg PF13012.1 GAP83300.1 - 0.016 15.2 0.7 1.2 9.2 0.1 2.7 1 1 0 2 2 2 0 Maintenance of mitochondrial structure and function FbpA PF05833.6 GAP83300.1 - 0.035 12.6 0.4 0.053 12.0 0.3 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) NPV_P10 PF05531.7 GAP83300.1 - 0.063 13.5 3.1 1.9 8.8 0.0 3.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 GAP83300.1 - 0.066 13.0 1.4 0.7 9.6 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.1 GAP83300.1 - 0.083 13.2 1.5 4.7 7.5 0.2 3.6 3 1 0 3 3 3 0 Snapin/Pallidin YCII PF03795.9 GAP83301.1 - 0.00031 20.8 0.0 0.00042 20.4 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain SP_C-Propep PF08999.5 GAP83302.1 - 0.0067 15.8 3.2 0.0097 15.3 2.2 1.4 1 0 0 1 1 1 1 Surfactant protein C, N terminal propeptide Rifin_STEVOR PF02009.11 GAP83302.1 - 0.036 13.7 0.3 0.038 13.6 0.2 1.1 1 0 0 1 1 1 0 Rifin/stevor family AMP-binding PF00501.23 GAP83303.1 - 1.3e-82 277.4 0.0 1.7e-82 277.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAP83303.1 - 7e-13 49.3 0.0 1.9e-12 47.9 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 GAP83303.1 - 0.00015 20.4 0.0 0.0021 16.6 0.0 2.0 2 0 0 2 2 2 1 GH3 auxin-responsive promoter G-patch PF01585.18 GAP83304.1 - 1.9e-12 46.7 1.9 4.8e-12 45.4 1.4 1.7 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 GAP83304.1 - 2.4e-05 24.1 0.0 5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAP83304.1 - 0.00043 19.8 0.0 0.0016 18.0 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP83304.1 - 0.018 14.9 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Recep_L_domain PF01030.19 GAP83305.1 - 8.9e-11 41.7 1.5 0.0054 16.6 0.0 3.5 2 1 1 3 3 3 3 Receptor L domain Ecm33 PF12454.3 GAP83305.1 - 0.0007 19.4 0.5 0.0023 17.7 0.3 2.0 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein Secretin_N_2 PF07655.8 GAP83305.1 - 0.56 10.6 8.1 1.4 9.3 5.6 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Tannase PF07519.6 GAP83306.1 - 1.2e-95 321.0 0.7 1.6e-95 320.5 0.5 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 GAP83306.1 - 0.00012 21.8 0.2 0.013 15.2 0.0 2.8 2 0 0 2 2 2 2 Alpha/beta hydrolase family HhH-GPD PF00730.20 GAP83307.1 - 3.6e-13 49.7 0.0 1.4e-12 47.8 0.0 2.0 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein Anp1 PF03452.9 GAP83308.1 - 2.9e-110 367.6 0.0 3.6e-110 367.3 0.0 1.1 1 0 0 1 1 1 1 Anp1 UCR_14kD PF02271.11 GAP83309.1 - 7.7e-43 144.5 0.3 1.1e-42 144.0 0.2 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.22 GAP83310.1 - 4e-68 225.1 3.0 2.3e-23 81.7 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Methyltransf_2 PF00891.13 GAP83312.1 - 1.1e-22 80.3 0.0 1.6e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 GAP83312.1 - 0.00029 20.6 0.1 0.00074 19.2 0.1 1.7 1 0 0 1 1 1 1 Dimerisation domain Rrf2 PF02082.15 GAP83312.1 - 0.0064 16.5 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator DUF977 PF06163.6 GAP83312.1 - 0.01 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) FeoC PF09012.5 GAP83312.1 - 0.095 12.4 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 FeoC like transcriptional regulator RVT_1 PF00078.22 GAP83315.1 - 4.3e-13 49.1 0.1 1e-12 47.8 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) KilA-N PF04383.8 GAP83317.1 - 0.00058 19.4 0.0 0.0083 15.7 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain BRCT PF00533.21 GAP83319.1 - 0.00015 21.8 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 GAP83319.1 - 0.00064 19.5 0.5 0.0019 17.9 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain DUF2975 PF11188.3 GAP83321.1 - 0.36 10.5 6.5 0.12 12.0 2.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) APH PF01636.18 GAP83323.1 - 1.8e-12 47.5 1.2 1.3e-10 41.3 0.8 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAP83323.1 - 3.2e-06 26.8 0.0 5.1e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 GAP83323.1 - 0.0076 15.4 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1236 PF06823.7 GAP83323.1 - 0.024 14.3 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1236) Pkinase PF00069.20 GAP83323.1 - 0.096 11.8 0.0 0.71 8.9 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain Pyr_redox_3 PF13738.1 GAP83324.1 - 2.6e-07 30.9 0.3 0.024 14.7 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAP83324.1 - 2.7e-07 30.5 0.3 1e-05 25.3 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 GAP83324.1 - 3.2e-07 30.2 0.0 9.6e-07 28.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAP83324.1 - 1.4e-05 24.1 1.2 0.00013 21.0 0.8 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAP83324.1 - 0.0018 17.3 0.1 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.19 GAP83324.1 - 0.0036 16.4 0.0 0.18 10.8 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 GAP83324.1 - 0.0044 16.9 0.1 0.016 15.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAP83324.1 - 0.0055 15.8 0.2 0.036 13.1 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 GAP83324.1 - 0.011 16.1 0.1 2.9 8.3 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAP83324.1 - 0.075 11.8 0.3 2.3 6.9 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Malic_M PF03949.10 GAP83324.1 - 0.16 11.4 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain HI0933_like PF03486.9 GAP83324.1 - 0.2 10.0 0.5 0.64 8.4 0.2 1.7 2 0 0 2 2 2 0 HI0933-like protein ELMO_CED12 PF04727.8 GAP83326.1 - 2.3e-48 163.9 0.2 6.2e-48 162.5 0.2 1.8 2 0 0 2 2 2 1 ELMO/CED-12 family DUF3361 PF11841.3 GAP83326.1 - 0.00017 21.3 0.0 0.0017 18.1 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3361) zf-GRF PF06839.7 GAP83327.1 - 0.00052 19.8 0.9 0.00091 19.1 0.6 1.4 1 0 0 1 1 1 1 GRF zinc finger DUF1772 PF08592.6 GAP83328.1 - 0.00036 20.2 5.2 0.011 15.5 2.4 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1772) adh_short_C2 PF13561.1 GAP83329.1 - 6.5e-20 71.9 0.0 8.8e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAP83329.1 - 3e-19 69.5 0.8 3.8e-19 69.2 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP83329.1 - 1.3e-07 31.5 1.5 4.6e-07 29.6 1.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 GAP83329.1 - 0.024 14.0 0.1 0.038 13.4 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAP83329.1 - 0.055 12.3 0.1 0.078 11.8 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 GAP83331.1 - 2.1e-29 102.6 5.1 4.4e-29 101.5 3.5 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP83331.1 - 1e-12 48.3 0.0 1.4e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP83331.1 - 4.3e-11 42.8 7.4 3.3e-10 39.9 5.1 2.1 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAP83331.1 - 6.1e-08 32.8 0.2 1.7e-07 31.4 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAP83331.1 - 2.1e-07 30.6 0.4 4.3e-07 29.6 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAP83331.1 - 3.6e-05 22.6 0.1 5.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 GAP83331.1 - 0.003 16.4 0.0 0.0069 15.3 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain TrkA_N PF02254.13 GAP83331.1 - 0.0092 15.9 0.0 0.023 14.7 0.0 1.7 1 1 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.14 GAP83331.1 - 0.025 13.7 0.0 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 GAP83331.1 - 0.16 11.6 0.6 0.51 9.9 0.3 1.9 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Indigoidine_A PF04227.7 GAP83333.1 - 9.4e-102 340.1 0.1 1.3e-101 339.7 0.1 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 GAP83333.1 - 1e-08 34.6 0.0 9e-08 31.5 0.0 2.5 2 1 0 2 2 2 1 pfkB family carbohydrate kinase WD40 PF00400.27 GAP83334.1 - 1.5e-09 37.3 0.3 0.018 14.9 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat PD40 PF07676.7 GAP83334.1 - 0.042 13.5 1.9 3.1 7.5 0.0 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat NUMOD1 PF07453.8 GAP83335.1 - 0.0025 17.5 0.0 2.7 7.9 0.0 2.4 2 0 0 2 2 2 2 NUMOD1 domain DUF3357 PF11837.3 GAP83338.1 - 0.14 12.0 0.9 0.18 11.6 0.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) FAP PF07174.6 GAP83338.1 - 3.9 6.7 15.4 0.84 8.8 7.8 1.8 1 1 1 2 2 2 0 Fibronectin-attachment protein (FAP) MFS_1 PF07690.11 GAP83339.1 - 1.4e-20 73.3 35.5 5e-20 71.5 22.2 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Aconitase PF00330.15 GAP83340.1 - 3.6e-143 477.4 0.0 2.1e-142 474.9 0.0 1.9 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 GAP83340.1 - 4.3e-36 123.9 0.0 9.4e-36 122.8 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Fungal_trans PF04082.13 GAP83341.1 - 9.1e-14 50.9 0.6 9.6e-13 47.5 0.2 2.6 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP83341.1 - 4.6e-10 39.2 8.2 4.6e-10 39.2 5.7 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_2 PF04909.9 GAP83342.1 - 1.2e-11 44.7 6.8 1.1e-10 41.5 2.1 2.0 1 1 1 2 2 2 2 Amidohydrolase T6SS_Vgr PF13296.1 GAP83342.1 - 0.1 12.4 0.2 0.84 9.5 0.0 2.1 2 0 0 2 2 2 0 Putative type VI secretion system Rhs element Vgr Methyltransf_6 PF03737.10 GAP83343.1 - 8.7e-27 93.8 0.0 1.1e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase Abhydrolase_3 PF07859.8 GAP83344.1 - 2.6e-56 190.5 0.4 3.3e-56 190.2 0.3 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP83344.1 - 1.3e-07 31.5 1.6 2.2e-07 30.7 1.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAP83344.1 - 4.4e-07 29.3 0.0 0.00091 18.5 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.23 GAP83344.1 - 3.5e-06 26.0 0.1 4.7e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 GAP83344.1 - 7.4e-05 22.7 11.0 0.00013 21.9 7.6 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 GAP83344.1 - 0.01 15.1 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family AXE1 PF05448.7 GAP83344.1 - 0.094 11.1 0.0 0.16 10.4 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) zf-C2H2 PF00096.21 GAP83346.1 - 1.7e-12 46.8 11.0 7.7e-06 25.9 1.6 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP83346.1 - 3.2e-11 42.7 11.4 3.7e-05 23.7 1.8 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAP83346.1 - 4.1e-10 39.4 2.1 5e-08 32.8 0.2 4.8 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_jaz PF12171.3 GAP83346.1 - 1.5e-06 28.1 5.2 0.029 14.5 0.1 4.0 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAP83346.1 - 2.9e-05 24.0 1.2 0.013 15.6 0.2 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type Zn_ribbon_recom PF13408.1 GAP83346.1 - 0.14 12.4 0.5 0.33 11.2 0.3 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2H2_6 PF13912.1 GAP83346.1 - 0.52 10.2 7.9 11 6.1 0.4 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger LIM PF00412.17 GAP83346.1 - 1.7 8.7 4.5 9.1 6.4 2.4 2.5 2 1 1 3 3 3 0 LIM domain ADH_zinc_N PF00107.21 GAP83347.1 - 4e-13 49.0 1.6 5.8e-13 48.5 0.3 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP83347.1 - 3.1e-07 30.1 0.4 1.2e-06 28.2 0.1 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain CENP-T PF15511.1 GAP83348.1 - 0.93 8.6 7.1 2.8 7.0 4.9 1.7 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T PP2C PF00481.16 GAP83350.1 - 2.3e-53 181.2 0.0 8.8e-53 179.2 0.0 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C LRR_4 PF12799.2 GAP83350.1 - 5.3e-49 163.1 65.2 5.5e-07 29.0 0.7 12.9 8 3 3 12 12 12 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAP83350.1 - 6.7e-38 128.2 59.1 8.7e-08 31.8 0.6 9.3 5 2 6 11 11 11 11 Leucine rich repeat Guanylate_cyc PF00211.15 GAP83350.1 - 6.6e-29 100.5 0.0 1.3e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 GAP83350.1 - 2.9e-21 72.2 68.4 0.19 11.8 0.0 19.9 19 1 0 19 19 19 10 Leucine Rich Repeat Ad_cyc_g-alpha PF08509.6 GAP83350.1 - 1.8e-17 62.4 3.2 1.8e-17 62.4 2.2 2.4 2 0 0 2 2 2 1 Adenylate cyclase G-alpha binding domain RA PF00788.18 GAP83350.1 - 4.9e-12 46.1 0.0 9.8e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_7 PF13504.1 GAP83350.1 - 2e-09 36.1 62.0 0.64 10.4 0.1 17.8 21 0 0 21 21 21 5 Leucine rich repeat LRR_6 PF13516.1 GAP83350.1 - 0.00037 20.2 57.7 0.87 9.8 0.0 16.7 17 2 2 19 19 19 2 Leucine Rich repeat Dynamitin PF04912.9 GAP83351.1 - 2e-35 122.3 10.5 3.1e-34 118.4 7.3 2.5 1 1 0 1 1 1 1 Dynamitin FH2 PF02181.18 GAP83351.1 - 3.7e-05 22.8 6.6 0.21 10.4 0.1 3.2 3 0 0 3 3 3 3 Formin Homology 2 Domain Sipho_Gp157 PF05565.6 GAP83351.1 - 0.00054 19.5 5.4 0.26 10.8 0.4 2.9 3 0 0 3 3 3 2 Siphovirus Gp157 Laminin_II PF06009.7 GAP83351.1 - 0.0026 17.5 11.8 0.072 12.8 0.2 4.1 2 1 2 4 4 4 2 Laminin Domain II Mnd1 PF03962.10 GAP83351.1 - 0.0052 16.4 10.4 0.023 14.3 0.3 3.1 3 0 0 3 3 3 1 Mnd1 family IFT57 PF10498.4 GAP83351.1 - 0.0088 14.8 5.0 0.29 9.8 0.0 3.2 3 0 0 3 3 3 1 Intra-flagellar transport protein 57 Spore_III_AB PF09548.5 GAP83351.1 - 0.025 14.3 3.9 0.83 9.3 0.0 3.4 4 0 0 4 4 3 0 Stage III sporulation protein AB (spore_III_AB) TPR_MLP1_2 PF07926.7 GAP83351.1 - 0.028 14.1 18.3 0.4 10.4 0.1 3.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Dor1 PF04124.7 GAP83351.1 - 0.029 12.8 4.1 0.52 8.7 0.0 3.0 3 0 0 3 3 3 0 Dor1-like family COG5 PF10392.4 GAP83351.1 - 0.069 13.1 7.5 0.15 12.0 0.1 3.1 3 0 0 3 3 3 0 Golgi transport complex subunit 5 DUF2203 PF09969.4 GAP83351.1 - 0.09 13.0 4.8 4.7 7.4 0.1 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) BLOC1_2 PF10046.4 GAP83351.1 - 0.12 12.5 10.9 2.2 8.4 0.2 4.3 4 1 0 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 VIT1 PF01988.14 GAP83351.1 - 0.17 11.3 0.7 0.34 10.3 0.5 1.5 1 1 0 1 1 1 0 VIT family DivIC PF04977.10 GAP83351.1 - 0.19 11.2 16.3 0.34 10.4 0.3 4.0 3 1 1 4 4 4 0 Septum formation initiator Tropomyosin_1 PF12718.2 GAP83351.1 - 0.22 11.3 16.1 1 9.2 0.6 3.3 3 0 0 3 3 3 0 Tropomyosin like Baculo_PEP_C PF04513.7 GAP83351.1 - 0.25 11.1 5.6 3.8 7.3 0.3 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus RmuC PF02646.11 GAP83351.1 - 0.35 9.6 7.0 5.7 5.6 0.3 3.0 3 0 0 3 3 3 0 RmuC family Fib_alpha PF08702.5 GAP83351.1 - 0.4 10.8 8.8 4.8 7.2 0.1 3.5 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family Bacillus_HBL PF05791.6 GAP83351.1 - 0.4 10.0 9.0 4.4 6.6 0.1 3.3 2 1 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) TMPIT PF07851.8 GAP83351.1 - 0.98 8.4 6.2 11 4.9 0.1 3.0 3 0 0 3 3 3 0 TMPIT-like protein DUF904 PF06005.7 GAP83351.1 - 2.1 8.6 12.7 3.1 8.1 0.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF904) Snapin_Pallidin PF14712.1 GAP83351.1 - 2.2 8.6 9.7 2.7 8.3 0.1 3.9 3 2 0 3 3 3 0 Snapin/Pallidin Fmp27_WPPW PF10359.4 GAP83351.1 - 2.5 6.4 8.1 0.5 8.7 0.2 2.7 2 1 1 3 3 3 0 RNA pol II promoter Fmp27 protein domain DUF342 PF03961.8 GAP83351.1 - 3.6 5.8 7.1 3.7 5.8 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF342) FlgN PF05130.7 GAP83351.1 - 3.9 7.7 19.9 2 8.6 2.5 3.2 2 1 1 3 3 3 0 FlgN protein DUF4254 PF14063.1 GAP83351.1 - 4.5 6.8 9.8 1.1 8.8 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF4254) Phage_GP20 PF06810.6 GAP83351.1 - 4.8 6.6 10.1 1.3 8.4 0.3 3.2 3 1 0 3 3 3 0 Phage minor structural protein GP20 DUF2884 PF11101.3 GAP83351.1 - 6.8 6.0 9.5 3.3 7.0 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2884) EzrA PF06160.7 GAP83351.1 - 7.8 4.5 10.2 2.2 6.3 0.2 3.0 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA Uds1 PF15456.1 GAP83351.1 - 8.1 6.4 17.9 7.9 6.4 2.1 3.7 2 2 0 3 3 3 0 Up-regulated During Septation YkyA PF10368.4 GAP83351.1 - 9.9 5.4 9.3 0.62 9.3 0.1 2.8 3 1 0 3 3 3 0 Putative cell-wall binding lipoprotein RTC4 PF14474.1 GAP83352.1 - 4.5e-35 120.3 0.1 9.6e-35 119.2 0.1 1.6 1 0 0 1 1 1 1 RTC4-like domain Cu-oxidase_3 PF07732.10 GAP83355.1 - 3.8e-20 71.7 0.0 7.9e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.17 GAP83355.1 - 5.9e-05 23.0 0.0 0.00018 21.4 0.0 1.7 1 1 0 1 1 1 1 Multicopper oxidase DUF2205 PF10224.4 GAP83356.1 - 3.1e-31 106.7 1.1 4.5e-31 106.2 0.8 1.2 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Myosin_tail_1 PF01576.14 GAP83356.1 - 0.007 14.1 1.0 0.0083 13.9 0.7 1.0 1 0 0 1 1 1 1 Myosin tail TACC PF05010.9 GAP83356.1 - 0.046 13.4 0.2 0.059 13.1 0.1 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) AAA_32 PF13654.1 GAP83356.1 - 0.054 12.1 0.1 0.055 12.1 0.1 1.1 1 0 0 1 1 1 0 AAA domain FYVE PF01363.16 GAP83358.1 - 1.1e-21 76.4 0.8 1.1e-21 76.4 0.6 2.4 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 GAP83358.1 - 8.2e-10 38.3 6.3 8.2e-10 38.3 4.4 3.3 3 0 0 3 3 3 1 Ring finger domain FYVE_2 PF02318.11 GAP83358.1 - 0.073 12.9 8.9 0.048 13.5 1.3 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger Rad50_zn_hook PF04423.9 GAP83358.1 - 0.25 10.8 2.5 0.94 8.9 0.4 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif RINGv PF12906.2 GAP83358.1 - 0.64 10.1 8.0 0.7 9.9 3.5 2.4 2 0 0 2 2 2 0 RING-variant domain zf-rbx1 PF12678.2 GAP83358.1 - 0.66 10.1 15.9 0.028 14.5 3.1 3.1 3 0 0 3 3 3 0 RING-H2 zinc finger DUF4428 PF14471.1 GAP83358.1 - 7.5 6.3 6.0 2.6 7.8 0.4 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) ABC_membrane PF00664.18 GAP83360.1 - 1.8e-72 244.0 36.9 1.3e-41 142.8 8.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAP83360.1 - 2.9e-60 202.5 0.6 6.9e-32 110.6 0.0 3.4 3 0 0 3 3 3 3 ABC transporter SMC_N PF02463.14 GAP83360.1 - 4.4e-12 45.7 3.1 0.00065 18.9 0.6 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAP83360.1 - 2.3e-10 40.9 5.9 0.031 14.2 0.0 4.6 4 1 1 5 5 5 3 AAA domain AAA_16 PF13191.1 GAP83360.1 - 9.4e-08 32.2 1.8 3.6e-06 27.0 0.1 2.9 3 0 0 3 3 3 1 AAA ATPase domain ABC_ATPase PF09818.4 GAP83360.1 - 5.7e-07 28.4 0.7 0.0058 15.2 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 GAP83360.1 - 0.0001 21.5 0.1 0.027 13.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAP83360.1 - 0.00016 21.7 1.5 0.14 12.2 0.1 4.0 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.1 GAP83360.1 - 0.00019 20.9 1.1 0.59 9.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 GAP83360.1 - 0.00024 20.9 0.9 0.44 10.4 0.1 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA PF00004.24 GAP83360.1 - 0.0015 18.7 0.3 13 6.0 0.0 3.7 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) BLVR PF06375.6 GAP83360.1 - 0.0019 18.0 3.3 0.0035 17.1 2.3 1.3 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) AAA_17 PF13207.1 GAP83360.1 - 0.0025 18.6 1.7 0.14 12.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain ATP-synt_ab PF00006.20 GAP83360.1 - 0.0068 15.9 0.6 0.34 10.3 0.0 3.0 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 GAP83360.1 - 0.017 14.5 0.5 1.4 8.3 0.0 3.0 4 0 0 4 4 4 0 AAA domain AAA_15 PF13175.1 GAP83360.1 - 0.068 12.2 1.7 0.08 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.1 GAP83360.1 - 2.4 7.6 8.2 0.93 9.0 0.1 3.8 4 1 0 4 4 4 0 AAA domain AAA_5 PF07728.9 GAP83360.1 - 4 7.1 5.4 1.9 8.2 0.0 3.1 5 0 0 5 5 5 0 AAA domain (dynein-related subfamily) G6PD_C PF02781.11 GAP83361.1 - 1.8e-134 447.2 0.0 2.6e-134 446.6 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 GAP83361.1 - 1e-63 214.8 0.0 1.7e-63 214.1 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain CZB PF13682.1 GAP83361.1 - 0.022 14.9 0.6 0.054 13.6 0.4 1.6 1 0 0 1 1 1 0 Chemoreceptor zinc-binding domain Ribosomal_L35Ae PF01247.13 GAP83362.1 - 1.7e-37 127.0 0.2 1.9e-37 126.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 GAP83362.1 - 1.8e-05 24.5 0.0 0.049 13.5 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain DUF2406 PF10295.4 GAP83363.1 - 1.2e-15 57.7 9.9 1.2e-15 57.7 6.9 3.6 3 1 0 3 3 3 1 Uncharacterised protein (DUF2406) TORC_M PF12885.2 GAP83363.1 - 0.27 10.9 8.4 1.1 9.0 5.8 2.0 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain PAT1 PF09770.4 GAP83363.1 - 8.8 4.4 47.4 0.39 8.8 27.5 1.9 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 VMA21 PF09446.5 GAP83364.1 - 2.9e-14 52.7 8.7 4.2e-14 52.2 6.0 1.2 1 0 0 1 1 1 1 VMA21-like domain STAG PF08514.6 GAP83364.1 - 0.099 12.3 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 STAG domain Pribosyl_synth PF14572.1 GAP83365.1 - 6.4e-41 140.1 2.4 1.7e-35 122.4 0.6 2.6 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 GAP83365.1 - 1.9e-28 98.4 0.3 5.7e-18 64.7 0.0 4.0 3 1 0 3 3 3 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 GAP83365.1 - 2.9e-12 46.4 0.5 5.8e-12 45.4 0.3 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 GAP83365.1 - 0.047 12.8 0.2 0.075 12.2 0.2 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Glyco_hydro_42C PF08533.5 GAP83365.1 - 0.078 12.5 0.0 11 5.5 0.0 2.4 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain SNF2_N PF00176.18 GAP83366.1 - 8.5e-57 192.2 0.3 1.4e-56 191.5 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAP83366.1 - 6.9e-11 41.8 0.0 1.7e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CENP-X PF09415.5 GAP83367.1 - 0.15 11.8 1.4 0.3 10.9 1.0 1.6 1 1 0 1 1 1 0 CENP-S associating Centromere protein X G-patch PF01585.18 GAP83368.1 - 3.6e-05 23.4 0.0 0.00016 21.3 0.0 2.3 1 0 0 1 1 1 1 G-patch domain MIP-T3 PF10243.4 GAP83368.1 - 0.27 9.6 53.5 0.37 9.2 37.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 NMO PF03060.10 GAP83370.1 - 2.3e-22 79.5 0.5 1.2e-18 67.3 0.1 2.6 1 1 1 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 GAP83370.1 - 0.028 13.3 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain RhoGAP PF00620.22 GAP83372.1 - 2.3e-43 147.4 0.4 5.7e-43 146.1 0.3 1.7 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 GAP83372.1 - 1.3e-10 41.4 0.0 3e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAP83372.1 - 2.2e-06 27.8 0.0 4.7e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3450 PF11932.3 GAP83372.1 - 0.00018 20.8 2.1 0.00041 19.6 1.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) PH_8 PF15409.1 GAP83372.1 - 0.008 16.2 0.0 0.036 14.1 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain Dpoe2NT PF12213.3 GAP83372.1 - 0.048 13.5 0.1 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal PX PF00787.19 GAP83372.1 - 0.14 11.9 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 PX domain bZIP_2 PF07716.10 GAP83373.1 - 2.3e-10 40.1 5.3 4.5e-10 39.2 3.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 GAP83373.1 - 4.2e-08 33.0 6.6 4.2e-08 33.0 4.6 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 GAP83373.1 - 0.00016 21.8 3.3 0.00032 20.9 2.3 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor SR-25 PF10500.4 GAP83373.1 - 0.0075 15.7 6.4 0.01 15.3 4.5 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Golgin_A5 PF09787.4 GAP83373.1 - 0.01 14.3 0.7 0.015 13.8 0.5 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF737 PF05300.6 GAP83373.1 - 0.37 10.7 5.2 0.75 9.7 3.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF737) Glyco_hydro_18 PF00704.23 GAP83374.1 - 4.9e-15 55.8 1.0 7.6e-15 55.1 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Amidoligase_2 PF12224.3 GAP83375.1 - 3.1e-17 63.0 0.0 1.8e-15 57.2 0.0 2.3 2 0 0 2 2 2 2 Putative amidoligase enzyme DUF4611 PF15387.1 GAP83375.1 - 6.4 6.9 16.7 3.8 7.7 0.5 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4611) Kinesin PF00225.18 GAP83377.1 - 4.7e-60 203.0 0.0 7.2e-60 202.4 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain HxxPF_rpt PF13745.1 GAP83377.1 - 0.065 13.5 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 HxxPF-repeated domain OmpH PF03938.9 GAP83377.1 - 0.091 12.6 5.0 0.25 11.2 3.4 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Glyco_hydro_53 PF07745.8 GAP83378.1 - 3.5e-100 335.0 0.0 5.3e-100 334.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 TMEM154 PF15102.1 GAP83378.1 - 0.0044 16.7 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family TMEM51 PF15345.1 GAP83378.1 - 0.038 13.6 0.0 0.038 13.6 0.0 1.7 2 0 0 2 2 2 0 Transmembrane protein 51 EphA2_TM PF14575.1 GAP83378.1 - 0.065 13.6 1.0 0.099 13.0 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF1183 PF06682.7 GAP83378.1 - 0.16 11.5 3.1 1.6 8.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) DUF912 PF06024.7 GAP83378.1 - 0.97 9.5 10.1 19 5.3 0.0 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Glyco_hydro_17 PF00332.13 GAP83379.1 - 0.00047 19.3 0.1 0.00067 18.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 ArabFuran-catal PF09206.6 GAP83380.1 - 1.3e-163 543.5 19.9 1.9e-163 543.0 13.8 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.8 GAP83380.1 - 6.5e-62 207.4 3.6 1.1e-61 206.7 2.5 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) HSP20 PF00011.16 GAP83381.1 - 3.8e-20 71.6 0.4 1.3e-13 50.6 0.1 2.5 2 0 0 2 2 2 2 Hsp20/alpha crystallin family YTH PF04146.10 GAP83382.1 - 2.3e-56 189.2 0.0 7.3e-56 187.6 0.0 1.7 2 0 0 2 2 2 1 YT521-B-like domain RRM_6 PF14259.1 GAP83382.1 - 0.014 15.3 0.0 0.047 13.6 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAP83382.1 - 0.026 14.1 0.0 0.081 12.5 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP83382.1 - 0.096 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Proteasome PF00227.21 GAP83383.1 - 3.5e-30 104.7 0.1 7e-30 103.7 0.1 1.5 1 1 0 1 1 1 1 Proteasome subunit PI3_PI4_kinase PF00454.22 GAP83384.1 - 3.9e-39 134.5 0.0 2.3e-38 132.0 0.0 2.3 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 GAP83384.1 - 2.8e-21 75.5 0.1 7.3e-21 74.1 0.1 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) LacY_symp PF01306.14 GAP83384.1 - 0.073 11.6 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 LacY proton/sugar symporter Trypsin_2 PF13365.1 GAP83385.1 - 3.5e-06 27.0 0.0 1.1e-05 25.3 0.0 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF972 PF06156.8 GAP83385.1 - 1.1 9.5 4.4 0.7 10.2 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Cation_efflux PF01545.16 GAP83387.1 - 1e-29 103.5 11.3 1.3e-29 103.1 7.8 1.1 1 0 0 1 1 1 1 Cation efflux family PBP1_TM PF14812.1 GAP83388.1 - 3.9 7.8 16.3 9.5 6.6 5.1 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DMRL_synthase PF00885.14 GAP83389.1 - 1.9e-41 141.0 0.1 2e-23 82.6 0.0 2.0 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase DNA_mis_repair PF01119.14 GAP83390.1 - 2.7e-10 39.7 0.0 5.5e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain Apolipoprotein PF01442.13 GAP83391.1 - 0.00029 20.4 4.1 0.00056 19.4 2.8 1.5 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF4351 PF14261.1 GAP83391.1 - 0.03 14.2 0.1 0.11 12.4 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) Lipoprotein_6 PF01441.14 GAP83391.1 - 0.089 12.6 4.2 0.093 12.5 1.7 2.0 2 0 0 2 2 2 0 Lipoprotein DUF3584 PF12128.3 GAP83391.1 - 0.12 9.6 7.5 0.14 9.4 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PV-1 PF06637.6 GAP83391.1 - 2.3 6.6 6.1 1.2 7.5 2.5 1.6 1 1 0 1 1 1 0 PV-1 protein (PLVAP) DUF2317 PF10079.4 GAP83391.1 - 2.9 6.4 6.6 2.8 6.4 2.7 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2317) WXG100 PF06013.7 GAP83391.1 - 3.9 7.5 7.5 1.6 8.7 1.5 3.0 1 1 0 2 2 2 0 Proteins of 100 residues with WXG DUF3708 PF12501.3 GAP83391.1 - 7.2 6.4 12.1 11 5.7 0.4 3.3 1 1 2 3 3 3 0 Phosphate ATP-binding cassette transporter AIG2_2 PF13772.1 GAP83392.1 - 2e-05 24.6 0.0 0.00088 19.3 0.0 2.2 2 0 0 2 2 2 2 AIG2-like family NAD_Gly3P_dh_N PF01210.18 GAP83393.1 - 9.5e-49 165.1 0.1 2.2e-48 163.9 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 GAP83393.1 - 3.7e-41 140.3 0.5 6.3e-41 139.5 0.4 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 GAP83393.1 - 0.0036 17.7 0.0 2 8.9 0.0 2.6 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent hDGE_amylase PF14701.1 GAP83394.1 - 2e-172 573.8 0.0 2.6e-172 573.5 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 GAP83394.1 - 4e-87 292.3 1.8 6e-86 288.4 0.1 2.7 2 1 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 GAP83394.1 - 2.4e-28 99.0 5.6 5.8e-12 45.3 0.4 4.2 1 1 3 4 4 4 3 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 GAP83394.1 - 4.1e-26 90.6 0.0 8.7e-26 89.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 GAP83394.1 - 3.2e-05 23.4 0.0 0.25 10.6 0.0 2.2 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Ctr PF04145.10 GAP83396.1 - 3.5e-33 114.6 8.4 6.6e-33 113.7 5.8 1.4 1 1 0 1 1 1 1 Ctr copper transporter family Ni_hydr_CYTB PF01292.15 GAP83396.1 - 0.0019 17.5 0.5 0.0022 17.4 0.4 1.1 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 NUDIX PF00293.23 GAP83397.1 - 4.7e-14 52.1 0.0 8.6e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Corona_nucleoca PF00937.13 GAP83397.1 - 0.028 13.3 5.6 0.041 12.8 3.9 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Pkinase PF00069.20 GAP83399.1 - 1.1e-77 260.7 0.0 1.5e-77 260.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP83399.1 - 1.1e-36 126.2 0.0 1.5e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 GAP83399.1 - 2e-16 59.8 0.0 4.4e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 GAP83399.1 - 1.6e-10 40.4 0.0 3.1e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 GAP83399.1 - 0.001 18.1 0.0 0.002 17.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 GAP83399.1 - 0.0065 15.3 0.1 0.015 14.1 0.0 1.5 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase APH PF01636.18 GAP83399.1 - 0.054 13.2 0.1 0.2 11.3 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 GAP83399.1 - 0.068 12.4 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL E1-E2_ATPase PF00122.15 GAP83400.1 - 4.8e-73 245.0 0.0 9.7e-73 243.9 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAP83400.1 - 1.2e-35 122.6 10.9 3.9e-20 72.1 1.2 2.8 2 1 1 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAP83400.1 - 7.7e-31 108.1 0.0 9.1e-30 104.6 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAP83400.1 - 1.5e-18 65.9 0.0 2.8e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 GAP83400.1 - 1.8e-14 53.4 0.0 3.5e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 GAP83400.1 - 8.3e-14 52.1 0.0 1.8e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAP83400.1 - 3.5e-05 23.5 0.6 0.00048 19.7 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.8 GAP83401.1 - 2e-35 121.0 0.0 3.6e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 GAP83401.1 - 6.4e-08 31.6 0.2 1.6e-07 30.4 0.1 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 GAP83401.1 - 0.032 13.8 0.0 0.42 10.1 0.0 2.1 2 0 0 2 2 2 0 ScpA/B protein Elongin_A PF06881.6 GAP83403.1 - 1.7e-21 76.6 0.2 3.7e-21 75.5 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A ubiquitin PF00240.18 GAP83404.1 - 1.8e-23 81.7 0.1 2e-23 81.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 GAP83404.1 - 4.5e-11 42.2 0.1 5e-11 42.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 GAP83404.1 - 0.00035 20.7 0.0 0.00041 20.5 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 GAP83404.1 - 0.0015 18.4 0.1 0.0052 16.6 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Band_7 PF01145.20 GAP83405.1 - 5.7e-23 81.7 2.7 8.3e-23 81.1 1.8 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family CSTF2_hinge PF14327.1 GAP83406.1 - 3.6e-31 107.0 1.6 3.6e-31 107.0 1.1 2.0 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 GAP83406.1 - 8.4e-22 76.5 0.0 1.5e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP83406.1 - 7.4e-16 57.8 0.0 2.3e-15 56.2 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP83406.1 - 3.3e-08 33.2 0.0 4.8e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 GAP83406.1 - 3.7e-05 22.8 5.0 3.7e-05 22.8 3.5 2.7 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal DUF3135 PF11333.3 GAP83406.1 - 0.13 12.4 3.5 0.097 12.8 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) CorA PF01544.13 GAP83407.1 - 8.4e-41 139.8 0.9 2.8e-39 134.8 0.6 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein NAD_binding_8 PF13450.1 GAP83408.1 - 2.2e-10 40.4 0.3 6.7e-10 38.8 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 GAP83408.1 - 1.3e-09 37.6 0.1 9.9e-05 21.5 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 GAP83408.1 - 2.5e-08 33.2 0.0 2e-05 23.7 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 GAP83408.1 - 0.00051 19.2 0.0 0.001 18.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 GAP83408.1 - 0.00067 19.4 0.0 0.037 13.8 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAP83408.1 - 0.00085 19.4 0.0 0.02 14.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAP83408.1 - 0.0053 16.6 0.4 0.15 11.9 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAP83408.1 - 0.0058 17.0 0.3 0.09 13.1 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase zf-CCCH_2 PF14608.1 GAP83409.1 - 1.4e-05 24.8 11.6 1.4e-05 24.8 8.0 5.6 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 GAP83409.1 - 0.00054 20.0 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) p450 PF00067.17 GAP83410.1 - 2.4e-58 197.7 0.0 1.7e-57 194.9 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 DpnII PF04556.7 GAP83410.1 - 0.12 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 DpnII restriction endonuclease Glyco_hydro_20 PF00728.17 GAP83411.1 - 5.5e-84 282.3 0.0 6.8e-84 282.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 GAP83411.1 - 1.1e-21 77.8 0.0 1.8e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 GAP83411.1 - 4.5e-07 30.4 0.0 3.8e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Aldedh PF00171.17 GAP83412.1 - 5.2e-186 618.4 0.4 6e-186 618.2 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 GAP83412.1 - 0.0038 16.4 0.0 0.13 11.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Aminotran_1_2 PF00155.16 GAP83413.1 - 1.8e-18 66.6 0.0 2.3e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 GAP83413.1 - 4e-05 22.3 0.0 0.00038 19.1 0.0 2.0 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 GAP83413.1 - 0.029 13.3 0.0 0.1 11.5 0.0 1.7 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_hydro_16 PF00722.16 GAP83414.1 - 6.3e-38 129.9 0.3 1.1e-37 129.1 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Topoisom_I_N PF02919.10 GAP83416.1 - 1.9e-97 324.7 2.2 1.9e-97 324.7 1.5 3.0 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 GAP83416.1 - 4e-85 284.6 7.1 4e-85 284.6 4.9 2.6 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 GAP83416.1 - 2.3e-30 104.0 0.1 7.2e-30 102.4 0.1 1.9 1 0 0 1 1 1 1 C-terminal topoisomerase domain ATP-synt PF00231.14 GAP83417.1 - 4.4e-71 239.5 2.1 5.1e-71 239.3 1.4 1.0 1 0 0 1 1 1 1 ATP synthase Amino_oxidase PF01593.19 GAP83418.1 - 7.9e-83 279.0 0.0 1.9e-82 277.7 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 GAP83418.1 - 4.4e-08 33.1 0.0 1.3e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.1 GAP83418.1 - 2.3e-07 30.7 0.3 5.5e-07 29.5 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box_2 PF09011.5 GAP83418.1 - 4e-07 30.2 5.2 8.8e-07 29.2 3.6 1.5 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 GAP83418.1 - 9.7e-05 22.5 5.8 9.7e-05 22.5 4.0 2.4 2 1 0 2 2 2 1 HMG (high mobility group) box DAO PF01266.19 GAP83418.1 - 0.0021 17.0 0.6 0.13 11.0 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Sec1 PF00995.18 GAP83419.1 - 1.9e-137 459.2 0.0 2.3e-137 459.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family UQ_con PF00179.21 GAP83420.1 - 1.2e-26 92.7 0.0 1.4e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAP83420.1 - 1.1e-07 31.7 0.0 1.3e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 GAP83420.1 - 0.00032 20.5 0.0 0.00039 20.2 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 GAP83420.1 - 0.0062 16.2 0.0 0.0088 15.7 0.0 1.2 1 0 0 1 1 1 1 UEV domain UFC1 PF08694.6 GAP83420.1 - 0.064 12.7 0.0 0.076 12.4 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Pkinase PF00069.20 GAP83422.1 - 1.7e-71 240.4 0.0 2.4e-71 239.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP83422.1 - 5e-34 117.5 0.0 7.1e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP83422.1 - 1.3e-05 24.3 0.0 1.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAP83422.1 - 0.00021 20.4 0.0 0.00039 19.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 GAP83422.1 - 0.00065 19.0 0.0 0.0018 17.6 0.0 1.7 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL KTI12 PF08433.5 GAP83423.1 - 0.053 12.7 0.0 0.074 12.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 TACC PF05010.9 GAP83424.1 - 0.099 12.3 0.1 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) DUF4172 PF13776.1 GAP83424.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4172) Med14 PF08638.6 GAP83425.1 - 4.8e-68 228.2 0.0 7.7e-68 227.5 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 ArfGap PF01412.13 GAP83427.1 - 2e-33 114.6 1.3 5.8e-33 113.1 0.0 2.5 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf PH PF00169.24 GAP83427.1 - 1e-11 44.9 0.1 2.9e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 PH domain Hemocyanin_C PF03723.9 GAP83428.1 - 0.071 12.2 0.0 0.08 12.0 0.0 1.1 1 0 0 1 1 1 0 Hemocyanin, ig-like domain Membr_traf_MHD PF10540.4 GAP83429.1 - 3e-20 72.4 0.2 8.6e-20 70.9 0.1 1.9 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 GAP83429.1 - 3.3e-16 58.8 0.1 8.1e-16 57.6 0.0 1.8 2 0 0 2 2 2 1 C2 domain DUF3819 PF12842.2 GAP83429.1 - 0.032 13.9 0.4 0.094 12.3 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) Microvir_lysis PF04517.7 GAP83429.1 - 0.16 11.7 1.5 0.39 10.5 1.0 1.6 1 0 0 1 1 1 0 Microvirus lysis protein (E), C terminus HAMP PF00672.20 GAP83431.1 - 4e-47 158.2 16.9 6.6e-10 39.0 0.1 7.0 6 0 0 6 6 6 6 HAMP domain HATPase_c PF02518.21 GAP83431.1 - 8.3e-30 102.7 0.0 2.7e-29 101.1 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAP83431.1 - 1.5e-26 92.5 0.3 4e-25 87.9 0.2 2.6 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 GAP83431.1 - 5.6e-18 64.6 0.6 5.6e-18 64.6 0.4 3.9 5 0 0 5 5 5 1 His Kinase A (phospho-acceptor) domain AAA_13 PF13166.1 GAP83431.1 - 0.1 11.0 19.3 0.14 10.5 3.5 3.3 1 1 1 3 3 3 0 AAA domain DUF2365 PF10157.4 GAP83431.1 - 0.18 11.6 15.0 22 4.9 0.0 6.9 5 2 0 6 6 6 0 Uncharacterized conserved protein (DUF2365) DUF883 PF05957.8 GAP83431.1 - 0.32 11.4 18.7 0.98 9.8 0.0 5.7 6 1 1 7 7 7 0 Bacterial protein of unknown function (DUF883) NAAA-beta PF15508.1 GAP83431.1 - 1.2 9.5 4.7 31 5.0 0.1 5.1 4 2 2 6 6 6 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase HrpB7 PF09486.5 GAP83432.1 - 0.019 14.9 1.5 0.023 14.6 1.1 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Tropomyosin PF00261.15 GAP83432.1 - 0.053 12.6 0.2 0.062 12.3 0.2 1.1 1 0 0 1 1 1 0 Tropomyosin Tropomyosin_1 PF12718.2 GAP83432.1 - 0.064 13.1 0.3 0.066 13.0 0.2 1.1 1 0 0 1 1 1 0 Tropomyosin like DUF2360 PF10152.4 GAP83432.1 - 3.3 7.9 5.5 1.4 9.2 0.3 2.0 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) HMG_box PF00505.14 GAP83433.1 - 2.8e-17 62.7 0.5 6e-17 61.6 0.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 GAP83433.1 - 2.7e-15 56.4 0.5 6.3e-15 55.3 0.3 1.6 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.25 GAP83433.1 - 2.9e-10 40.1 0.0 5e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 GAP83433.1 - 6.2e-07 29.1 0.0 1.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Cnd2 PF05786.9 GAP83434.1 - 5.5e-217 722.7 6.0 8.3e-217 722.1 4.2 1.2 1 0 0 1 1 1 1 Condensin complex subunit 2 Lipase_GDSL_2 PF13472.1 GAP83434.1 - 0.094 12.8 0.4 3.5 7.7 0.0 2.5 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family ADC PF06314.6 GAP83435.1 - 0.0016 17.8 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Fungal_trans PF04082.13 GAP83436.1 - 2.1e-10 39.9 0.1 3.9e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP83436.1 - 2.5e-07 30.5 8.6 2.5e-07 30.5 6.0 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-MYND PF01753.13 GAP83437.1 - 0.00046 20.0 10.9 0.0008 19.2 7.6 1.4 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.8 GAP83437.1 - 0.07 10.8 2.4 0.096 10.3 1.7 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 2OG-FeII_Oxy_3 PF13640.1 GAP83438.1 - 0.018 15.5 0.0 0.034 14.6 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily p450 PF00067.17 GAP83439.1 - 3.3e-57 194.0 0.0 1.1e-41 142.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Stirrup PF09061.1 GAP83439.1 - 0.15 12.0 0.0 0.42 10.5 0.0 1.7 1 0 0 1 1 1 0 Stirrup MFS_1 PF07690.11 GAP83440.1 - 1.2e-36 126.1 27.9 1.2e-36 126.1 19.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 GAP83440.1 - 0.0035 16.8 0.4 0.0035 16.8 0.3 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF4231 PF14015.1 GAP83440.1 - 0.07 13.1 0.5 0.07 13.1 0.3 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF4231) DUF4229 PF14012.1 GAP83440.1 - 0.89 9.4 9.7 0.13 12.1 2.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) 7tm_2 PF00002.19 GAP83441.1 - 8.7e-10 38.0 9.3 8.7e-10 38.0 6.4 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 GAP83441.1 - 4.2e-08 32.4 9.5 4.2e-08 32.4 6.6 1.8 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.16 GAP83441.1 - 4.6e-07 29.2 3.3 7.2e-07 28.6 2.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.3 GAP83441.1 - 1e-06 28.4 13.2 1.7e-06 27.7 9.2 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 MFS_1 PF07690.11 GAP83442.1 - 2.2e-33 115.4 23.2 2.2e-33 115.4 16.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3311 PF11755.3 GAP83442.1 - 0.23 11.0 7.2 2.1 7.9 0.0 4.7 6 0 0 6 6 6 0 Protein of unknown function (DUF3311) PDZ_2 PF13180.1 GAP83443.1 - 6.3e-07 29.2 0.1 2.2e-06 27.4 0.1 2.0 1 1 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.9 GAP83443.1 - 2.1e-05 24.5 0.0 6.1e-05 23.0 0.0 1.8 1 1 1 2 2 2 1 GRASP55/65 PDZ-like domain PDZ PF00595.19 GAP83443.1 - 0.0003 20.8 0.0 0.00049 20.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Ras PF00071.17 GAP83444.1 - 7.5e-49 165.2 0.0 9e-49 164.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAP83444.1 - 8.4e-15 55.3 0.0 1.7e-14 54.3 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAP83444.1 - 4.4e-10 39.0 0.0 5.7e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 GAP83444.1 - 0.00053 20.1 0.1 0.0053 16.9 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 GAP83444.1 - 0.0043 16.2 0.0 0.0056 15.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.7 GAP83444.1 - 0.026 13.8 0.1 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.15 GAP83444.1 - 0.064 11.9 1.9 0.94 8.0 0.1 2.3 2 1 1 3 3 3 0 G-protein alpha subunit AAA_33 PF13671.1 GAP83444.1 - 0.08 12.8 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAP83444.1 - 0.082 13.0 0.2 0.32 11.1 0.1 2.0 1 1 1 2 2 2 0 AAA domain UPF0079 PF02367.12 GAP83444.1 - 0.14 11.8 0.1 0.25 10.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 E1-E2_ATPase PF00122.15 GAP83445.1 - 3.3e-64 216.0 7.5 9.6e-64 214.5 5.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAP83445.1 - 1.2e-44 152.0 5.3 1.2e-44 152.0 3.7 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAP83445.1 - 3.3e-33 115.9 0.0 4.2e-32 112.2 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAP83445.1 - 1.9e-23 82.2 0.0 3.7e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 GAP83445.1 - 1.3e-19 69.4 0.0 3.8e-19 67.9 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 GAP83445.1 - 1.3e-18 67.9 0.2 3.8e-18 66.3 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAP83445.1 - 8e-10 38.7 1.9 1.3e-06 28.2 0.9 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 GAP83445.1 - 0.0023 18.1 0.0 0.006 16.8 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 GAP83445.1 - 0.0072 16.2 0.0 0.034 14.0 0.0 2.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase GHL6 PF14871.1 GAP83445.1 - 0.039 13.9 0.0 2.7 8.0 0.0 2.6 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 Proteasome PF00227.21 GAP83446.1 - 9.9e-43 145.6 0.0 1.2e-42 145.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TUG-UBL1 PF11470.3 GAP83447.1 - 6.4e-22 77.2 0.1 1.6e-21 76.0 0.1 1.7 1 0 0 1 1 1 1 GLUT4 regulating protein TUG Rad60-SLD PF11976.3 GAP83447.1 - 8.2e-05 22.2 0.0 0.00018 21.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBX PF00789.15 GAP83447.1 - 0.087 12.8 0.0 0.3 11.1 0.0 1.9 2 0 0 2 2 2 0 UBX domain Mif2_N PF15624.1 GAP83447.1 - 0.63 10.6 5.1 0.38 11.3 1.6 2.1 2 1 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Ribosomal_L36e PF01158.13 GAP83448.1 - 3.9e-36 122.9 8.8 4.3e-36 122.8 6.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 GAP83448.1 - 0.12 11.5 0.9 0.13 11.3 0.6 1.1 1 0 0 1 1 1 0 LemA family RhoGEF PF00621.15 GAP83449.1 - 4.7e-25 88.4 0.0 7.3e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain DUF4638 PF15472.1 GAP83449.1 - 0.038 13.5 0.8 0.071 12.6 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) SBDS PF01172.13 GAP83450.1 - 4.9e-24 83.9 0.6 5.8e-24 83.6 0.4 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein OsmC PF02566.14 GAP83450.1 - 0.11 12.7 0.1 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 OsmC-like protein 7TMR-DISM_7TM PF07695.6 GAP83451.1 - 0.12 12.0 5.2 0.21 11.2 3.6 1.4 1 1 0 1 1 1 0 7TM diverse intracellular signalling OPA3 PF07047.7 GAP83453.1 - 4.2e-40 136.6 1.3 8.2e-40 135.6 0.9 1.5 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DltD_M PF04918.7 GAP83453.1 - 0.084 13.0 1.5 0.096 12.8 0.2 1.6 2 0 0 2 2 2 0 DltD central region Pkinase PF00069.20 GAP83454.1 - 1.3e-67 227.6 0.0 1.8e-67 227.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP83454.1 - 3.3e-42 144.3 0.0 4.6e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP83454.1 - 1.3e-07 30.9 0.0 2.2e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like POLO_box PF00659.13 GAP83454.1 - 3.6e-07 30.0 0.0 0.001 18.9 0.0 2.9 2 0 0 2 2 2 2 POLO box duplicated region Kdo PF06293.9 GAP83454.1 - 0.0018 17.3 0.0 0.0032 16.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Sel1 PF08238.7 GAP83455.1 - 1e-35 121.3 29.7 7.9e-06 26.3 0.2 7.5 6 1 1 7 7 7 7 Sel1 repeat Chitin_synth_2 PF03142.10 GAP83456.1 - 4.5e-291 965.8 0.1 6e-291 965.4 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 GAP83456.1 - 8.3e-17 61.5 1.9 2.8e-16 59.8 1.3 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAP83456.1 - 1.5e-14 54.4 0.0 1.8e-13 50.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 GAP83456.1 - 1e-12 47.6 0.1 2.5e-09 36.7 0.0 2.5 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 GAP83456.1 - 0.0009 18.5 0.0 0.016 14.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 GAP83456.1 - 0.13 11.9 0.0 0.69 9.5 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 WD40 PF00400.27 GAP83457.1 - 4.8e-11 42.0 0.1 8.2e-09 35.0 0.1 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF2415 PF10313.4 GAP83457.1 - 0.0028 17.3 0.0 0.0089 15.6 0.0 1.9 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) PQQ PF01011.16 GAP83457.1 - 0.067 12.7 0.0 0.21 11.2 0.0 1.9 1 0 0 1 1 1 0 PQQ enzyme repeat Glyco_hydro_17 PF00332.13 GAP83458.1 - 0.0048 15.9 0.0 0.13 11.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 DUF2105 PF09878.4 GAP83459.1 - 0.026 14.0 0.2 0.03 13.9 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2105) MraY_sig1 PF10555.4 GAP83459.1 - 3.7 7.0 6.4 1.8 8.0 0.8 2.7 2 0 0 2 2 2 0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 RNB PF00773.14 GAP83460.1 - 8.5e-64 215.8 0.0 1.3e-63 215.2 0.0 1.3 1 0 0 1 1 1 1 RNB domain DUF1752 PF08550.5 GAP83461.1 - 1.1e-08 34.4 2.0 2.2e-08 33.5 1.4 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Met_10 PF02475.11 GAP83462.1 - 2.7e-70 236.0 0.0 3.5e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 GAP83462.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TRM PF02005.11 GAP83462.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase 2OG-FeII_Oxy_2 PF13532.1 GAP83463.1 - 1.6e-27 96.6 0.0 2e-26 93.0 0.0 2.5 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 GAP83463.1 - 2.6e-05 24.4 0.0 4.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Prenyltransf PF01255.14 GAP83464.1 - 4.4e-06 25.9 0.0 0.00028 20.0 0.0 2.2 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase DUF3291 PF11695.3 GAP83464.1 - 0.085 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3291) DUF2415 PF10313.4 GAP83464.1 - 0.098 12.3 0.2 0.22 11.2 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) Sec10 PF07393.6 GAP83465.1 - 1.1e-212 708.1 6.7 2.1e-212 707.2 4.7 1.4 1 1 0 1 1 1 1 Exocyst complex component Sec10 Hpt PF01627.18 GAP83465.1 - 0.041 13.8 0.9 1.5 8.9 0.0 3.2 2 0 0 2 2 2 0 Hpt domain Homeobox PF00046.24 GAP83466.1 - 2.9e-14 52.4 1.9 7.3e-14 51.1 1.3 1.7 1 0 0 1 1 1 1 Homeobox domain NAD_kinase PF01513.16 GAP83467.1 - 3.3e-70 236.0 0.0 4.6e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase RNase_PH PF01138.16 GAP83468.1 - 3.2e-11 43.6 0.0 6.2e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 GAP83468.1 - 0.11 12.4 0.0 0.91 9.5 0.0 2.2 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 PTPA PF03095.10 GAP83469.1 - 1.3e-110 369.3 0.0 1.5e-110 369.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Ank_2 PF12796.2 GAP83471.1 - 1.8e-52 175.6 0.0 2.4e-15 56.6 0.0 6.1 5 1 4 9 9 9 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAP83471.1 - 5.8e-41 138.1 0.0 2.7e-09 37.2 0.0 8.2 8 0 0 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.25 GAP83471.1 - 4.8e-36 120.7 10.4 7.3e-06 25.5 0.0 10.5 11 0 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.1 GAP83471.1 - 5.2e-34 115.4 1.9 3.3e-09 36.7 0.0 8.3 7 2 3 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP83471.1 - 4.1e-27 91.5 0.1 0.0019 18.2 0.0 10.4 10 0 0 10 10 10 5 Ankyrin repeat NACHT PF05729.7 GAP83471.1 - 4.6e-05 23.1 0.0 0.00027 20.6 0.0 2.4 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 GAP83471.1 - 8.6e-05 22.5 0.0 0.00023 21.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAP83471.1 - 0.03 14.4 0.0 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Anp1 PF03452.9 GAP83472.1 - 6e-108 360.0 0.0 7.5e-108 359.7 0.0 1.1 1 0 0 1 1 1 1 Anp1 UQ_con PF00179.21 GAP83473.1 - 8.2e-28 96.5 0.0 8.9e-28 96.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAP83473.1 - 0.0076 16.0 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B CDC45 PF02724.9 GAP83474.1 - 1.6 6.6 2.9 2.8 5.8 2.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Cgr1 PF03879.9 GAP83475.1 - 1.1e-36 125.2 30.9 1.3e-36 125.0 21.4 1.0 1 0 0 1 1 1 1 Cgr1 family PH_4 PF15404.1 GAP83475.1 - 0.066 12.7 5.8 0.075 12.5 4.0 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain PRP1_N PF06424.7 GAP83475.1 - 0.24 11.7 10.7 0.3 11.3 7.4 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Birna_RdRp PF04197.7 GAP83475.1 - 0.82 7.6 7.5 0.83 7.6 5.2 1.0 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) GAGA_bind PF06217.7 GAP83475.1 - 0.89 9.4 13.6 0.97 9.3 9.4 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family HCMV_UL139 PF12507.3 GAP83476.1 - 0.0023 18.1 1.8 0.0072 16.4 1.3 1.8 1 1 0 1 1 1 1 Human Cytomegalovirus UL139 protein Fib_alpha PF08702.5 GAP83476.1 - 0.014 15.4 7.4 0.021 14.9 4.4 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family T4SS PF07996.6 GAP83476.1 - 0.015 15.1 7.6 0.021 14.7 4.5 1.6 1 1 0 1 1 1 0 Type IV secretion system proteins CorA PF01544.13 GAP83476.1 - 0.53 9.2 5.3 5.8 5.8 3.7 2.3 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF607 PF04678.8 GAP83476.1 - 0.92 9.4 5.0 4.5 7.1 3.4 2.2 1 1 0 1 1 1 0 Protein of unknown function, DUF607 DUF2205 PF10224.4 GAP83476.1 - 1.9 8.1 5.9 6.9 6.3 1.1 2.8 2 1 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) GAS PF13851.1 GAP83476.1 - 1.9 7.6 9.4 0.36 10.0 2.9 2.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3818 PF12825.2 GAP83477.1 - 1.3e-134 448.1 3.7 1.9e-134 447.6 2.5 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 GAP83477.1 - 1e-42 144.9 0.2 2.6e-42 143.6 0.1 1.6 1 0 0 1 1 1 1 PX-associated PX PF00787.19 GAP83477.1 - 5.2e-17 61.6 0.6 1.5e-15 56.9 0.0 3.3 3 1 0 3 3 3 1 PX domain FAD_binding_2 PF00890.19 GAP83478.1 - 7.3e-125 417.0 3.4 8.9e-125 416.7 2.3 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 GAP83478.1 - 4.2e-46 155.9 0.2 6.3e-46 155.4 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 GAP83478.1 - 1.5e-06 28.2 0.0 0.0048 16.8 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAP83478.1 - 1.3e-05 24.2 1.1 0.038 12.8 1.3 3.0 3 0 0 3 3 3 2 Glucose inhibited division protein A Thi4 PF01946.12 GAP83478.1 - 3.5e-05 23.0 0.4 0.026 13.6 0.0 2.5 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 GAP83478.1 - 0.00068 18.6 0.1 0.0027 16.6 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 GAP83478.1 - 0.0022 17.1 0.7 0.0039 16.3 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain DUF600 PF04634.7 GAP83478.1 - 0.085 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF600 HI0933_like PF03486.9 GAP83478.1 - 0.17 10.3 0.6 0.61 8.4 0.2 2.0 2 0 0 2 2 2 0 HI0933-like protein adh_short PF00106.20 GAP83479.1 - 1.9e-23 83.2 3.3 3.1e-23 82.5 2.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP83479.1 - 3.2e-21 76.2 0.1 3.6e-21 76.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP83479.1 - 1.4e-10 41.1 1.0 2e-10 40.6 0.7 1.2 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.11 GAP83480.1 - 4.9e-37 127.4 22.4 4.9e-37 127.4 15.5 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP83480.1 - 2.3e-17 62.7 2.8 2.3e-17 62.7 2.0 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 GAP83480.1 - 0.0043 15.3 1.9 0.0098 14.1 1.3 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 GAP83481.1 - 1.3e-12 47.1 1.2 2.6e-12 46.1 0.5 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 GAP83481.1 - 8.2e-09 35.2 14.1 8e-06 25.8 1.2 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type Zn_clus PF00172.13 GAP83481.1 - 2.5e-06 27.3 9.9 2.5e-06 27.3 6.8 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 GAP83481.1 - 6e-06 26.2 13.0 0.01 16.1 0.1 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAP83481.1 - 8.2e-05 22.7 6.5 0.0014 18.8 0.4 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 GAP83481.1 - 0.24 11.6 4.5 0.65 10.2 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Vps39_2 PF10367.4 GAP83481.1 - 0.46 10.6 0.0 0.46 10.6 0.0 2.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Ribosomal_L37ae PF01780.14 GAP83481.1 - 4.5 7.2 8.5 0.45 10.4 1.0 2.7 2 1 0 2 2 2 0 Ribosomal L37ae protein family Ank PF00023.25 GAP83482.1 - 7.8e-10 38.0 0.2 0.00056 19.5 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 GAP83482.1 - 3e-09 36.2 0.1 0.0007 19.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 GAP83482.1 - 4.5e-08 33.3 0.0 2.1e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAP83482.1 - 0.00014 22.2 1.3 0.0015 18.9 0.2 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP83482.1 - 0.00054 20.1 0.4 2.5 8.4 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) BDV_P10 PF06515.6 GAP83482.1 - 0.41 10.4 0.1 0.41 10.4 0.0 2.6 3 0 0 3 3 3 0 Borna disease virus P10 protein SSP160 PF06933.6 GAP83482.1 - 5.5 4.8 13.9 1.3 6.8 4.0 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Beta_helix PF13229.1 GAP83483.1 - 2e-08 34.1 17.9 6.4e-08 32.5 12.4 1.9 1 1 0 1 1 1 1 Right handed beta helix region Chondroitinas_B PF14592.1 GAP83483.1 - 9.1e-07 28.0 0.0 1.5e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Chondroitinase B DUF1565 PF07602.6 GAP83483.1 - 0.01 14.9 0.5 0.01 14.9 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1565) MGC-24 PF05283.6 GAP83484.1 - 7.5 6.2 17.4 0.091 12.5 6.5 1.8 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) eIF3_subunit PF08597.5 GAP83485.1 - 1.8e-68 230.7 18.1 2e-68 230.6 12.6 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit IRF PF00605.12 GAP83485.1 - 0.12 12.1 1.2 0.29 10.9 0.8 1.6 1 0 0 1 1 1 0 Interferon regulatory factor transcription factor FNIP_N PF14636.1 GAP83485.1 - 0.27 11.6 7.1 0.2 12.1 2.2 2.1 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus Spore_coat_CotO PF14153.1 GAP83485.1 - 5.4 6.4 14.4 0.28 10.6 5.1 2.0 2 0 0 2 2 2 0 Spore coat protein CotO DUF2413 PF10310.4 GAP83485.1 - 8.1 5.1 23.1 0.29 9.9 9.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) MDM31_MDM32 PF08118.6 GAP83486.1 - 3.9e-183 609.5 0.0 6.8e-183 608.7 0.0 1.3 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins KH_1 PF00013.24 GAP83487.1 - 5.6e-05 22.7 0.6 0.00011 21.7 0.4 1.4 1 0 0 1 1 1 1 KH domain GMC_oxred_N PF00732.14 GAP83488.1 - 1.6e-27 96.4 0.0 6.5e-19 68.1 0.0 3.2 3 0 0 3 3 3 2 GMC oxidoreductase GMC_oxred_C PF05199.8 GAP83488.1 - 9.3e-26 90.8 0.0 2e-25 89.7 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAP83488.1 - 2.4e-05 23.4 0.0 0.00083 18.3 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAP83488.1 - 0.00016 21.6 0.0 0.0054 16.6 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP83488.1 - 0.00035 20.5 0.0 0.0011 18.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAP83488.1 - 0.0048 16.9 0.0 0.27 11.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAP83488.1 - 0.007 15.2 0.6 0.019 13.8 0.1 1.9 3 0 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.14 GAP83488.1 - 0.03 13.3 0.1 0.047 12.7 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 GAP83488.1 - 0.046 12.1 0.1 0.1 11.0 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein ApbA PF02558.11 GAP83488.1 - 0.2 11.0 0.1 0.43 10.0 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_hydro_15 PF00723.16 GAP83489.1 - 1.4e-51 175.5 0.0 6.1e-46 156.9 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 IL10 PF00726.12 GAP83489.1 - 0.13 11.5 0.0 0.41 9.9 0.0 1.8 2 0 0 2 2 2 0 Interleukin 10 F-box-like PF12937.2 GAP83490.1 - 0.00011 21.9 0.3 0.00022 20.8 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAP83490.1 - 0.004 16.7 0.3 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 F-box domain Bromo_TP PF07524.8 GAP83491.1 - 0.00026 20.6 0.0 0.00041 20.0 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TAFII55_N PF04658.8 GAP83492.1 - 3.3e-41 140.4 0.0 6.6e-41 139.5 0.0 1.5 1 0 0 1 1 1 1 TAFII55 protein conserved region YL1 PF05764.8 GAP83492.1 - 0.84 9.2 42.0 0.044 13.3 7.4 3.2 3 0 0 3 3 3 0 YL1 nuclear protein Ribosomal_L37 PF08561.5 GAP83493.1 - 6.9e-29 99.2 3.6 3.2e-21 74.7 0.1 2.3 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L37 DUF2011 PF09428.5 GAP83493.1 - 0.08 12.8 3.4 0.19 11.5 2.3 1.6 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF2011) Dicty_REP PF05086.7 GAP83493.1 - 0.24 9.0 1.6 0.27 8.9 1.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 GAP83493.1 - 3.4 7.4 25.9 4.5 7.0 17.2 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein Pkinase PF00069.20 GAP83494.1 - 1.8e-06 27.2 0.5 3.1e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.9 GAP83494.1 - 6.4e-05 22.1 0.0 0.00016 20.7 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAP83494.1 - 0.00021 21.1 0.1 0.00021 21.1 0.1 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family HSDR_N_2 PF13588.1 GAP83494.1 - 0.0039 16.9 0.0 1.4 8.7 0.0 2.5 2 0 0 2 2 2 2 Type I restriction enzyme R protein N terminus (HSDR_N) Choline_kinase PF01633.15 GAP83494.1 - 0.0082 15.7 0.1 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Seadorna_VP7 PF07387.6 GAP83494.1 - 0.02 13.7 0.1 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_Tyr PF07714.12 GAP83494.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Macoilin PF09726.4 GAP83494.1 - 0.2 9.9 13.9 0.0066 14.8 5.4 1.5 2 0 0 2 2 2 0 Transmembrane protein NDUFB10 PF10249.4 GAP83495.1 - 0.00054 20.1 0.1 0.00061 19.9 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.9 GAP83495.1 - 0.052 13.9 0.0 0.083 13.3 0.0 1.3 1 0 0 1 1 1 0 HWE histidine kinase Ank_2 PF12796.2 GAP83496.1 - 3.7e-07 30.3 0.0 1.4e-06 28.5 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAP83496.1 - 0.00011 21.8 0.0 0.12 12.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 GAP83496.1 - 0.0052 17.2 0.0 4.9 7.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP83496.1 - 0.012 15.7 0.0 7.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP83496.1 - 0.017 15.3 0.0 3.8 8.0 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat AAA_16 PF13191.1 GAP83497.1 - 4.4e-05 23.5 0.0 6.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAP83497.1 - 0.00066 19.8 0.1 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAP83497.1 - 0.0011 18.7 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 GAP83497.1 - 0.0013 18.4 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 NACHT domain APS_kinase PF01583.15 GAP83497.1 - 0.0016 18.1 0.1 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.1 GAP83497.1 - 0.0026 18.5 0.1 0.0087 16.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 GAP83497.1 - 0.0049 17.0 0.0 0.0071 16.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 GAP83497.1 - 0.0089 15.1 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.17 GAP83497.1 - 0.018 15.1 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase cobW PF02492.14 GAP83497.1 - 0.019 14.4 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 GAP83497.1 - 0.026 14.8 0.0 0.053 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 GAP83497.1 - 0.034 13.6 0.1 0.052 13.0 0.1 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 GAP83497.1 - 0.044 12.7 0.0 0.062 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 GAP83497.1 - 0.062 12.7 0.2 0.11 11.8 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein Thymidylate_kin PF02223.12 GAP83497.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Thymidylate kinase RRM_1 PF00076.17 GAP83498.1 - 1.7e-37 126.8 0.5 3.4e-18 65.0 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP83498.1 - 3.1e-32 110.3 0.0 1.6e-15 56.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP83498.1 - 8.1e-14 51.2 0.0 1.9e-05 24.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Herpes_pp38 PF04846.8 GAP83499.1 - 0.031 13.5 0.1 0.071 12.4 0.1 1.5 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein Pkinase PF00069.20 GAP83500.1 - 1.5e-60 204.5 0.0 5.1e-39 133.9 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAP83500.1 - 1.5e-27 96.3 0.0 4.5e-20 71.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 GAP83500.1 - 1.5e-13 50.7 0.0 2.9e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 GAP83500.1 - 2.7e-08 33.1 0.1 1e-05 24.6 0.0 2.8 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 GAP83500.1 - 1.2e-06 28.5 0.1 0.0041 16.8 0.1 3.2 2 1 0 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 GAP83500.1 - 0.024 13.7 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 GAP83500.1 - 0.054 12.3 0.0 0.095 11.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 TMEM247 PF15444.1 GAP83500.1 - 4.3 7.0 4.6 42 3.8 0.1 3.4 3 0 0 3 3 3 0 Transmembrane protein 247 bZIP_1 PF00170.16 GAP83502.1 - 0.00038 20.3 7.4 0.0011 18.8 5.1 1.8 1 0 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.13 GAP83502.1 - 0.064 13.2 0.3 0.16 11.9 0.2 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF904 PF06005.7 GAP83502.1 - 1.2 9.4 6.4 0.19 12.0 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF904) NYD-SP28_assoc PF14775.1 GAP83502.1 - 1.7 8.3 7.3 0.23 11.1 1.6 2.0 1 1 1 2 2 2 0 Sperm tail C-terminal domain bZIP_2 PF07716.10 GAP83502.1 - 2 8.3 10.9 14 5.6 7.5 2.1 1 1 0 1 1 1 0 Basic region leucine zipper DUF2205 PF10224.4 GAP83502.1 - 3.2 7.4 8.1 0.81 9.2 3.1 1.8 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) eIF-3_zeta PF05091.7 GAP83503.1 - 1.3e-197 657.5 0.0 1.6e-197 657.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.8 GAP83503.1 - 0.0063 15.9 0.1 0.015 14.7 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF569) Ribul_P_3_epim PF00834.14 GAP83504.1 - 6.8e-64 214.6 0.0 3.6e-63 212.3 0.0 1.9 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 GAP83504.1 - 0.085 12.2 0.1 0.17 11.2 0.1 1.5 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Aminotran_5 PF00266.14 GAP83505.1 - 2.1e-42 145.2 0.0 6.6e-37 127.1 0.0 2.9 3 0 0 3 3 3 3 Aminotransferase class-V Fringe PF02434.11 GAP83506.1 - 4.5e-10 39.1 0.0 9.8e-08 31.5 0.0 3.0 2 1 0 2 2 2 1 Fringe-like Acetyltransf_6 PF13480.1 GAP83506.1 - 0.0046 16.9 3.3 0.062 13.2 0.2 3.2 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain PAN_4 PF14295.1 GAP83506.1 - 0.0099 15.5 2.0 0.023 14.3 1.4 1.6 1 0 0 1 1 1 1 PAN domain Glyco_transf_34 PF05637.7 GAP83506.1 - 0.27 10.7 1.3 0.45 9.9 0.9 1.2 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family Ofd1_CTDD PF10637.4 GAP83507.1 - 9.8e-96 319.9 0.0 2.3e-89 299.0 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 GAP83507.1 - 4.2e-15 56.0 0.0 1.3e-14 54.5 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 GAP83507.1 - 0.022 14.3 0.0 0.051 13.2 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily TFIIF_alpha PF05793.7 GAP83507.1 - 3.4 5.9 24.3 0.025 12.9 10.8 1.9 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Metallophos PF00149.23 GAP83508.1 - 3.3e-08 33.1 1.4 8.8e-08 31.7 1.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase WBS_methylT PF12589.3 GAP83508.1 - 1.3 9.5 12.4 1.6 9.2 2.1 2.8 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome His_Phos_1 PF00300.17 GAP83509.1 - 4.9e-13 49.4 0.0 6.5e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Stk19 PF10494.4 GAP83510.1 - 1.6e-27 96.5 0.0 3.2e-27 95.5 0.0 1.4 1 1 0 1 1 1 1 Serine-threonine protein kinase 19 LexA_DNA_bind PF01726.11 GAP83510.1 - 0.069 12.7 0.0 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 LexA DNA binding domain Kinesin PF00225.18 GAP83511.1 - 4.5e-97 324.7 0.0 7e-97 324.1 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Atg14 PF10186.4 GAP83511.1 - 5.2 5.9 9.7 7 5.4 3.0 2.9 3 0 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 p450 PF00067.17 GAP83513.1 - 1.5e-68 231.4 0.0 1.8e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3045 PF11243.3 GAP83513.1 - 0.12 12.5 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3045) DUF3074 PF11274.3 GAP83514.1 - 2.6e-33 115.2 0.1 3.5e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) CRT10 PF08728.5 GAP83515.1 - 1.1e-07 30.3 0.0 6.1e-07 27.8 0.0 2.1 2 1 0 2 2 2 1 CRT10 Ammonium_transp PF00909.16 GAP83516.1 - 1.2e-110 369.7 28.6 1.4e-110 369.5 19.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family SieB PF14163.1 GAP83516.1 - 0.053 13.0 1.3 0.56 9.7 0.0 2.2 2 0 0 2 2 2 0 Superinfection exclusion protein B DUF3185 PF11381.3 GAP83516.1 - 1.1 9.0 8.1 6 6.7 0.2 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) COX2-transmemb PF09125.5 GAP83516.1 - 9.4 5.8 7.4 3.1 7.4 0.0 3.0 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane Fungal_trans PF04082.13 GAP83517.1 - 5e-28 97.6 0.0 4.7e-27 94.4 0.0 2.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP83517.1 - 2.3e-09 37.0 7.6 3.9e-09 36.2 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4306 PF14154.1 GAP83517.1 - 0.13 12.2 0.2 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) DcpS_C PF11969.3 GAP83518.1 - 9.8e-29 99.9 0.7 2.7e-28 98.5 0.5 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 GAP83518.1 - 2.1e-25 89.2 0.0 3.4e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Hexokinase_1 PF00349.16 GAP83519.1 - 7.6e-25 87.4 0.0 1.3e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 GAP83519.1 - 3.7e-21 75.4 0.0 1.1e-20 73.8 0.0 1.8 1 1 0 1 1 1 1 Hexokinase DUF1951 PF09188.5 GAP83519.1 - 0.026 14.4 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1951) MFS_1 PF07690.11 GAP83520.1 - 2.5e-42 144.8 52.4 1.3e-41 142.4 33.5 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP83520.1 - 1.9e-12 46.4 8.9 1.9e-12 46.4 6.2 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 GAP83520.1 - 7.6e-07 27.7 6.4 7.6e-07 27.7 4.4 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Myb_Cef PF11831.3 GAP83521.1 - 2.6e-60 203.5 1.5 2.6e-60 203.5 1.0 3.6 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 GAP83521.1 - 1.8e-22 79.1 3.9 1.7e-10 40.7 0.2 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAP83521.1 - 2.1e-21 75.7 8.1 5.7e-15 55.1 1.8 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.3 GAP83521.1 - 0.048 13.5 1.0 2 8.3 0.0 3.4 2 1 1 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF2560 PF10834.3 GAP83521.1 - 0.11 12.4 4.4 7.6 6.5 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2560) Ribosomal_S8e PF01201.17 GAP83521.1 - 1.1 9.4 10.3 0.033 14.3 1.0 2.6 2 0 0 2 2 2 0 Ribosomal protein S8e Cyt-b5 PF00173.23 GAP83523.1 - 1.5e-13 50.3 0.0 1.9e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PRA1 PF03208.14 GAP83523.1 - 0.045 13.0 0.0 0.061 12.6 0.0 1.1 1 0 0 1 1 1 0 PRA1 family protein MACPF PF01823.14 GAP83524.1 - 6.1e-09 35.8 0.5 1.7e-08 34.4 0.1 1.7 1 1 1 2 2 2 1 MAC/Perforin domain Glyco_transf_15 PF01793.11 GAP83525.1 - 1.2e-117 392.5 4.5 1.5e-117 392.2 3.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase EXS PF03124.9 GAP83526.1 - 2.4e-101 339.2 1.9 2.8e-101 339.0 1.3 1.0 1 0 0 1 1 1 1 EXS family Pex2_Pex12 PF04757.9 GAP83527.1 - 2.6e-44 151.3 1.2 3.5e-44 150.9 0.8 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 GAP83527.1 - 2.6e-12 46.3 8.1 4.6e-12 45.5 5.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAP83527.1 - 5.9e-12 45.4 7.7 9.5e-12 44.7 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAP83527.1 - 5.3e-10 38.7 6.4 9.2e-10 38.0 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAP83527.1 - 7.6e-10 38.3 6.2 1.2e-09 37.6 4.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAP83527.1 - 2.1e-08 33.7 5.5 3.3e-08 33.1 3.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 GAP83527.1 - 6.2e-07 29.1 7.7 1e-06 28.4 5.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 GAP83527.1 - 6.1e-05 22.7 2.7 0.00011 21.8 1.9 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 GAP83527.1 - 0.00016 21.7 8.1 0.00054 20.0 5.6 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 GAP83527.1 - 0.00082 19.0 4.6 0.0016 18.0 3.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 GAP83527.1 - 0.0032 16.9 0.9 0.0053 16.2 0.6 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit TerY-C PF15616.1 GAP83527.1 - 0.091 12.6 2.0 0.17 11.8 1.4 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_4 PF14570.1 GAP83527.1 - 0.096 12.2 8.0 0.18 11.4 5.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Dicty_REP PF05086.7 GAP83527.1 - 0.11 10.2 5.4 0.15 9.8 3.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-Apc11 PF12861.2 GAP83527.1 - 0.2 11.5 4.3 0.53 10.1 3.0 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Mucin PF01456.12 GAP83527.1 - 0.92 9.2 22.0 1.8 8.3 15.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein IBR PF01485.16 GAP83527.1 - 2.2 8.2 7.3 6 6.8 5.1 1.7 1 1 0 1 1 1 0 IBR domain SSP160 PF06933.6 GAP83527.1 - 2.6 5.9 14.9 4 5.2 10.3 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-LYAR PF08790.6 GAP83528.1 - 3e-08 33.2 0.2 5.7e-08 32.3 0.2 1.5 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger Abhydrolase_5 PF12695.2 GAP83529.1 - 4.3e-22 78.4 0.0 6.6e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP83529.1 - 5.1e-17 62.5 0.0 2.4e-15 57.0 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP83529.1 - 4.2e-08 33.0 0.0 0.00012 21.6 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.7 GAP83529.1 - 3.3e-07 29.1 0.0 0.022 13.2 0.0 3.1 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 GAP83529.1 - 5.9e-05 22.3 0.0 0.00013 21.2 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 GAP83529.1 - 0.00033 20.1 0.0 0.03 13.7 0.0 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.8 GAP83529.1 - 0.00038 19.9 0.0 0.00084 18.8 0.0 1.6 2 0 0 2 2 2 1 Serine hydrolase (FSH1) DUF818 PF05677.7 GAP83529.1 - 0.00051 18.8 0.0 0.00078 18.2 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DLH PF01738.13 GAP83529.1 - 0.00086 18.6 0.0 0.013 14.7 0.0 2.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 GAP83529.1 - 0.0011 18.5 0.0 0.0022 17.6 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 GAP83529.1 - 0.011 15.3 0.2 0.049 13.2 0.1 2.2 1 1 0 1 1 1 0 PGAP1-like protein BAAT_C PF08840.6 GAP83529.1 - 0.015 14.9 0.0 0.39 10.3 0.0 2.2 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.3 GAP83529.1 - 0.032 14.1 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Thioredoxin PF00085.15 GAP83531.1 - 3.5e-65 216.2 3.8 3.8e-32 110.0 0.1 4.0 4 1 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 GAP83531.1 - 8.9e-53 178.8 2.3 4.1e-39 134.2 0.1 3.7 3 2 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 GAP83531.1 - 5.6e-12 45.8 3.9 6.2e-05 23.1 0.1 4.3 2 2 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 GAP83531.1 - 8.1e-12 45.0 0.9 8.9e-05 22.4 0.0 3.3 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_8 PF13905.1 GAP83531.1 - 1e-10 41.6 0.1 0.00022 21.2 0.0 3.6 3 1 1 4 4 4 2 Thioredoxin-like Calsequestrin PF01216.12 GAP83531.1 - 6.8e-09 34.9 0.9 6.8e-09 34.9 0.6 2.2 3 1 0 3 3 3 1 Calsequestrin Redoxin PF08534.5 GAP83531.1 - 2e-07 30.6 4.0 0.0018 17.8 0.0 3.3 2 1 0 3 3 3 2 Redoxin AhpC-TSA PF00578.16 GAP83531.1 - 2.7e-07 30.2 1.2 0.0056 16.3 0.1 3.1 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_4 PF13462.1 GAP83531.1 - 2.3e-05 24.4 1.8 0.068 13.1 0.0 3.7 3 1 0 3 3 3 2 Thioredoxin ERp29_N PF07912.8 GAP83531.1 - 0.00021 21.1 0.4 2.5 8.0 0.0 3.9 3 2 0 3 3 3 1 ERp29, N-terminal domain DSBA PF01323.15 GAP83531.1 - 0.0031 17.1 0.1 16 4.9 0.0 4.1 3 1 1 4 4 4 0 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.1 GAP83531.1 - 0.0031 17.2 1.5 0.011 15.5 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin domain Mon1 PF03164.9 GAP83533.1 - 1.5e-117 392.7 0.0 1.8e-117 392.4 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 Dopey_N PF04118.9 GAP83534.1 - 7.5e-117 389.5 0.0 6.3e-116 386.4 0.0 2.3 2 0 0 2 2 2 1 Dopey, N-terminal bZIP_1 PF00170.16 GAP83535.1 - 0.016 15.1 13.3 0.05 13.5 9.2 1.8 1 1 0 1 1 1 0 bZIP transcription factor DivIC PF04977.10 GAP83535.1 - 0.033 13.6 5.1 0.076 12.5 3.5 1.6 1 1 0 1 1 1 0 Septum formation initiator Atg14 PF10186.4 GAP83535.1 - 0.095 11.6 5.1 0.15 10.9 3.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Prominin PF05478.6 GAP83535.1 - 0.34 8.3 0.5 0.5 7.8 0.3 1.1 1 0 0 1 1 1 0 Prominin bZIP_Maf PF03131.12 GAP83535.1 - 0.81 10.0 12.3 1.7 9.0 8.5 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor BTV_NS2 PF04514.7 GAP83535.1 - 2 7.2 8.2 3.4 6.4 5.7 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF3584 PF12128.3 GAP83535.1 - 3.9 4.6 13.5 5.1 4.2 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Bap31 PF05529.7 GAP83535.1 - 4.2 6.7 7.5 7.2 6.0 5.2 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like BEX PF04538.7 GAP83535.1 - 6 7.1 12.0 1.2 9.3 2.7 2.5 3 0 0 3 3 3 0 Brain expressed X-linked like family HET PF06985.6 GAP83536.1 - 0.00038 20.6 1.3 0.25 11.5 0.6 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) RRN3 PF05327.6 GAP83537.1 - 3.3e-167 557.0 0.0 3.3e-167 557.0 0.0 2.1 3 0 0 3 3 3 1 RNA polymerase I specific transcription initiation factor RRN3 DUF885 PF05960.6 GAP83537.1 - 0.0079 15.4 0.2 0.014 14.6 0.2 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) CBFD_NFYB_HMF PF00808.18 GAP83538.1 - 4.2e-29 100.4 0.9 5.5e-29 100.0 0.6 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAP83538.1 - 8.4e-07 29.0 0.1 1.3e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 GAP83538.1 - 0.00097 18.9 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 GAP83538.1 - 0.0018 17.9 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 GAP83538.1 - 0.036 14.3 0.1 0.11 12.8 0.0 1.7 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Prefoldin_2 PF01920.15 GAP83539.1 - 1.7e-26 92.0 9.7 1.9e-26 91.8 6.7 1.0 1 0 0 1 1 1 1 Prefoldin subunit IncA PF04156.9 GAP83539.1 - 0.0021 17.6 4.6 0.0026 17.3 3.2 1.1 1 0 0 1 1 1 1 IncA protein Syntaxin-6_N PF09177.6 GAP83539.1 - 0.0062 16.9 4.3 0.21 12.0 0.5 2.1 1 1 1 2 2 2 1 Syntaxin 6, N-terminal Tho2 PF11262.3 GAP83539.1 - 0.012 14.6 3.5 0.2 10.6 0.1 2.0 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 GAS PF13851.1 GAP83539.1 - 0.015 14.4 8.4 0.025 13.7 5.8 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF2205 PF10224.4 GAP83539.1 - 0.02 14.4 7.1 0.094 12.2 0.3 2.1 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) IMD PF08397.6 GAP83539.1 - 0.024 13.9 1.8 0.03 13.6 1.2 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain V_ATPase_I PF01496.14 GAP83539.1 - 0.025 12.4 2.7 0.03 12.2 1.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin PF02996.12 GAP83539.1 - 0.031 13.9 7.3 0.16 11.6 0.3 2.3 1 1 1 2 2 2 0 Prefoldin subunit DUF641 PF04859.7 GAP83539.1 - 0.071 12.8 5.0 0.11 12.2 0.3 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) CDC37_N PF03234.9 GAP83539.1 - 0.098 12.9 5.0 0.12 12.6 3.5 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding FliJ PF02050.11 GAP83539.1 - 0.1 12.6 5.8 1.1 9.2 0.4 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein Mnd1 PF03962.10 GAP83539.1 - 0.13 11.9 7.3 0.26 10.9 5.1 1.5 1 1 0 1 1 1 0 Mnd1 family DUF4200 PF13863.1 GAP83539.1 - 0.21 11.5 5.2 0.28 11.1 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) p25-alpha PF05517.7 GAP83539.1 - 0.28 11.4 3.6 1.1 9.5 0.2 2.0 1 1 0 2 2 2 0 p25-alpha FTA4 PF13093.1 GAP83539.1 - 0.36 10.2 5.9 0.59 9.5 3.8 1.5 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 STAT_alpha PF01017.15 GAP83539.1 - 0.39 10.4 7.5 0.54 9.9 5.2 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain DASH_Dad3 PF08656.5 GAP83539.1 - 0.61 9.8 5.7 0.49 10.1 1.6 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad3 Seryl_tRNA_N PF02403.17 GAP83539.1 - 0.74 9.8 7.6 1.3 9.0 0.8 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF948 PF06103.6 GAP83539.1 - 0.88 9.4 5.1 9.2 6.2 0.3 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Phage_GP20 PF06810.6 GAP83539.1 - 1.5 8.2 10.5 0.5 9.8 1.2 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 GP41 PF00517.12 GAP83539.1 - 1.7 8.1 6.0 0.67 9.4 0.8 1.9 1 1 0 2 2 2 0 Retroviral envelope protein bZIP_Maf PF03131.12 GAP83539.1 - 2.3 8.5 5.4 6.7 7.0 1.1 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor Spc24 PF08286.6 GAP83539.1 - 2.3 7.9 10.6 1 9.0 2.3 2.1 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 TMF_DNA_bd PF12329.3 GAP83539.1 - 5.6 6.8 11.6 1 9.2 2.9 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 GAP83539.1 - 6.1 5.7 8.9 18 4.2 6.0 1.7 1 1 0 1 1 1 0 Autophagy protein Apg6 Tmemb_14 PF03647.8 GAP83540.1 - 5.6e-24 84.3 8.2 6.4e-24 84.1 5.7 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF1427 PF07235.6 GAP83540.1 - 3 7.9 7.4 18 5.4 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1427) DAD PF02109.11 GAP83541.1 - 2e-49 166.3 1.1 2.4e-49 166.0 0.8 1.1 1 0 0 1 1 1 1 DAD family TrbL PF04610.9 GAP83541.1 - 0.012 15.2 0.4 0.018 14.7 0.2 1.4 1 1 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein GRASP55_65 PF04495.9 GAP83542.1 - 9.1e-44 148.8 0.0 5.4e-43 146.2 0.0 1.9 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain Methyltransf_15 PF09445.5 GAP83543.1 - 9.4e-41 139.0 0.0 1.2e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.11 GAP83543.1 - 1.4e-06 28.0 0.0 1.7e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 GAP83543.1 - 1.3e-05 25.2 0.0 1.9e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP83543.1 - 0.0002 21.8 0.0 0.00036 21.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 GAP83543.1 - 0.001 18.7 0.0 0.0016 18.0 0.0 1.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_3 PF01596.12 GAP83543.1 - 0.0059 15.6 0.0 0.0089 15.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase N6_Mtase PF02384.11 GAP83543.1 - 0.012 14.7 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase DNA_methylase PF00145.12 GAP83543.1 - 0.051 12.6 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase DSPc PF00782.15 GAP83544.1 - 7.3e-24 83.8 0.0 9.5e-24 83.4 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain HEAT_2 PF13646.1 GAP83545.1 - 8.4e-40 134.9 17.2 1.2e-07 31.9 2.1 6.7 2 2 5 8 8 8 8 HEAT repeats Cnd1 PF12717.2 GAP83545.1 - 1.8e-21 76.7 14.4 0.085 12.7 0.0 11.1 2 2 8 10 10 10 8 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 GAP83545.1 - 7.4e-20 69.2 22.9 0.38 10.9 0.0 11.8 12 0 0 12 12 11 6 HEAT repeat NACHT PF05729.7 GAP83545.1 - 5.4e-19 68.4 0.0 1.4e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain HEAT_EZ PF13513.1 GAP83545.1 - 7.4e-18 64.4 30.7 0.001 19.4 1.7 10.5 5 3 6 11 11 11 7 HEAT-like repeat Vac14_Fab1_bd PF12755.2 GAP83545.1 - 2.9e-14 53.2 15.1 0.052 13.9 0.1 10.7 2 2 9 11 11 11 2 Vacuolar 14 Fab1-binding region V-ATPase_H_C PF11698.3 GAP83545.1 - 5.3e-10 39.2 5.9 20 5.1 0.0 10.3 7 3 4 11 11 10 0 V-ATPase subunit H Adaptin_N PF01602.15 GAP83545.1 - 4.7e-09 35.0 5.1 9.7e-06 24.1 0.1 4.5 2 2 0 2 2 2 1 Adaptin N terminal region NB-ARC PF00931.17 GAP83545.1 - 1.4e-06 27.4 0.0 2.4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Nipped-B_C PF12830.2 GAP83545.1 - 2.9e-05 23.7 11.9 4.1 7.0 0.0 7.2 4 2 5 9 9 9 1 Sister chromatid cohesion C-terminus SopA PF13981.1 GAP83545.1 - 6.4e-05 22.9 0.1 3.6 7.6 0.0 4.2 2 2 0 3 3 3 2 SopA-like central domain AAA_22 PF13401.1 GAP83545.1 - 0.00015 21.9 0.5 0.0032 17.6 0.0 3.2 2 1 0 2 2 2 1 AAA domain SEN1_N PF12726.2 GAP83545.1 - 0.00041 18.5 0.0 0.16 9.9 0.0 3.0 2 1 1 3 3 3 1 SEN1 N terminal Arm PF00514.18 GAP83545.1 - 0.00054 19.6 13.8 16 5.4 0.0 8.7 10 0 0 10 10 9 0 Armadillo/beta-catenin-like repeat AAA_17 PF13207.1 GAP83545.1 - 0.0021 18.8 0.2 0.012 16.4 0.0 2.5 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 GAP83545.1 - 0.0026 18.0 0.0 0.01 16.1 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA PF00004.24 GAP83545.1 - 0.0056 16.8 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sec6 PF06046.8 GAP83545.1 - 0.0066 14.5 0.1 1.2 7.1 0.0 2.9 1 1 1 2 2 2 1 Exocyst complex component Sec6 AAA_19 PF13245.1 GAP83545.1 - 0.039 13.6 0.0 0.17 11.6 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain Aconitase_B_N PF11791.3 GAP83545.1 - 0.042 13.6 0.1 49 3.7 0.0 4.3 4 0 0 4 4 4 0 Aconitate B N-terminal domain NTPase_1 PF03266.10 GAP83545.1 - 0.045 13.4 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 NTPase DUF1827 PF08860.5 GAP83545.1 - 0.075 13.1 0.4 31 4.7 0.0 4.0 3 2 2 5 5 5 0 Domain of unknown function (DUF1827) AAA_24 PF13479.1 GAP83545.1 - 0.075 12.6 0.0 1.1 8.7 0.0 2.5 2 1 1 3 3 3 0 AAA domain PduV-EutP PF10662.4 GAP83545.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 GAP83545.1 - 0.15 11.8 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B APP_E2 PF12925.2 GAP83545.1 - 0.21 11.1 0.5 4.6 6.7 0.5 2.5 2 1 0 2 2 2 0 E2 domain of amyloid precursor protein Drf_GBD PF06371.8 GAP83545.1 - 0.53 9.6 2.0 95 2.2 0.0 4.5 6 1 0 6 6 5 0 Diaphanous GTPase-binding Domain RasGEF_N_2 PF14663.1 GAP83545.1 - 1.1 9.2 13.5 47 3.9 0.1 6.1 3 2 2 7 7 6 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Cas_GSU0054 PF09609.5 GAP83545.1 - 2.4 6.8 6.4 20 3.8 0.2 3.3 2 1 2 4 4 4 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) WSC PF01822.14 GAP83546.1 - 1.4e-52 175.5 45.3 1.5e-18 66.5 7.7 3.3 3 0 0 3 3 3 3 WSC domain Glyoxal_oxid_N PF07250.6 GAP83546.1 - 3e-27 95.2 0.0 3.8e-26 91.6 0.0 2.6 4 0 0 4 4 4 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 GAP83546.1 - 3.2e-19 68.8 0.0 6e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) R3H PF01424.17 GAP83547.1 - 3.6e-13 48.9 0.1 7.7e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 GAP83547.1 - 1.7e-05 24.6 25.7 0.00029 20.7 8.3 7.6 7 2 1 8 8 8 2 NF-X1 type zinc finger zf-HIT PF04438.11 GAP83548.1 - 7.6e-08 31.8 4.4 1.1e-07 31.3 3.0 1.3 1 0 0 1 1 1 1 HIT zinc finger Lactonase PF10282.4 GAP83551.1 - 0.00019 20.6 0.0 0.0058 15.7 0.0 2.6 1 1 0 2 2 2 2 Lactonase, 7-bladed beta-propeller bZIP_1 PF00170.16 GAP83552.1 - 9.4e-05 22.2 0.4 9.4e-05 22.2 0.3 1.6 2 0 0 2 2 2 1 bZIP transcription factor TIP39 PF14980.1 GAP83552.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 TIP39 peptide WLM PF08325.5 GAP83553.1 - 3.2e-50 170.5 0.4 8.6e-50 169.1 0.3 1.6 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.12 GAP83553.1 - 5.7e-08 32.7 0.2 5.7e-08 32.7 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function DUF45 DZR PF12773.2 GAP83553.1 - 1 9.2 7.6 0.31 10.9 1.1 2.4 1 1 0 2 2 2 0 Double zinc ribbon zf-RanBP PF00641.13 GAP83553.1 - 1.6 7.9 7.4 0.072 12.2 0.8 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF4110 PF13422.1 GAP83554.1 - 7.5e-29 99.4 0.1 7.5e-29 99.4 0.1 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.1 GAP83554.1 - 7.4e-24 83.3 13.9 1.7e-08 34.3 0.0 6.7 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.1 GAP83554.1 - 4.9e-21 74.2 1.1 3.5e-07 30.0 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.1 GAP83554.1 - 4e-16 58.5 17.4 9.2e-05 22.1 0.2 6.8 5 2 1 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.10 GAP83554.1 - 1.9e-13 49.5 6.0 0.0014 18.2 0.0 6.2 6 1 0 6 6 6 3 Kelch motif Kelch_6 PF13964.1 GAP83554.1 - 3.5e-12 45.9 4.7 0.001 19.1 0.2 5.7 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.20 GAP83554.1 - 6.2e-10 38.4 0.6 0.00014 21.3 0.0 5.2 5 0 0 5 5 5 1 Kelch motif Mito_carr PF00153.22 GAP83555.1 - 2.8e-65 216.0 0.3 1.3e-22 79.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TspO_MBR PF03073.10 GAP83556.1 - 4.7e-42 143.0 2.6 5.5e-42 142.7 1.8 1.1 1 0 0 1 1 1 1 TspO/MBR family DUF3546 PF12066.3 GAP83557.1 - 1.5e-25 89.3 1.4 1.5e-25 89.3 1.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) DUF4187 PF13821.1 GAP83557.1 - 5.5e-24 83.5 0.1 1.2e-23 82.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.8 GAP83557.1 - 2.7e-10 40.7 1.8 7.1e-10 39.4 1.3 1.8 1 0 0 1 1 1 1 Arsenite-resistance protein 2 GvpL_GvpF PF06386.6 GAP83557.1 - 0.78 9.2 8.5 0.52 9.8 0.2 2.3 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Ribonuc_L-PSP PF01042.16 GAP83558.1 - 4.3e-24 84.5 0.0 5.5e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP Sulf_transp PF04143.9 GAP83559.1 - 4.8e-12 45.6 28.7 1.7e-09 37.5 7.0 4.7 5 1 1 6 6 6 2 Sulphur transport ADH_zinc_N PF00107.21 GAP83560.1 - 1.9e-19 69.4 0.2 3.6e-19 68.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAP83560.1 - 1.6e-11 45.1 0.8 1.1e-10 42.4 0.0 2.3 2 1 1 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP83560.1 - 8.2e-05 22.3 0.0 0.00016 21.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SMK-1 PF04802.10 GAP83561.1 - 5e-75 251.2 1.3 1.7e-74 249.5 0.9 2.0 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 RNase_H2-Ydr279 PF09468.5 GAP83561.1 - 0.15 11.2 4.0 1.1 8.4 0.0 2.4 1 1 1 2 2 2 0 Ydr279p protein family (RNase H2 complex component) Kelch_4 PF13418.1 GAP83563.1 - 0.00055 19.6 0.4 0.29 10.9 0.0 2.9 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 GAP83563.1 - 0.00076 19.5 0.0 2.1 8.6 0.1 2.8 2 0 0 2 2 2 2 Kelch motif F5_F8_type_C PF00754.20 GAP83563.1 - 0.0079 16.0 0.3 0.014 15.2 0.2 1.3 1 0 0 1 1 1 1 F5/8 type C domain Kelch_2 PF07646.10 GAP83563.1 - 0.01 15.6 0.1 0.48 10.2 0.1 2.6 2 0 0 2 2 2 1 Kelch motif Glyoxal_oxid_N PF07250.6 GAP83563.1 - 0.024 13.7 0.1 0.18 10.8 0.0 2.1 1 1 0 2 2 2 0 Glyoxal oxidase N-terminus Kelch_5 PF13854.1 GAP83563.1 - 0.026 14.4 0.2 6.4 6.8 0.0 2.8 2 0 0 2 2 2 0 Kelch motif MFS_1 PF07690.11 GAP83564.1 - 1.9e-25 89.3 77.0 2.9e-24 85.4 32.9 3.0 1 1 1 3 3 3 3 Major Facilitator Superfamily PufQ PF05398.6 GAP83565.1 - 0.11 12.5 0.3 0.63 10.1 0.2 2.2 2 0 0 2 2 2 0 PufQ cytochrome subunit Caps_synth PF05704.7 GAP83566.1 - 1.6e-16 60.2 0.0 2.9e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 GAP83566.1 - 0.00017 21.9 0.0 0.00047 20.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Vfa1 PF08432.5 GAP83567.1 - 0.0015 18.5 29.8 0.0031 17.5 20.7 1.4 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 GAP83567.1 - 0.0032 15.5 5.1 0.0049 14.9 3.5 1.2 1 0 0 1 1 1 1 CDC45-like protein SAPS PF04499.10 GAP83567.1 - 0.0034 16.0 3.1 0.0047 15.6 2.1 1.2 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein DUF262 PF03235.9 GAP83567.1 - 0.0075 16.2 2.4 0.018 14.9 1.6 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF262 DDHD PF02862.12 GAP83567.1 - 0.017 14.9 7.6 0.041 13.6 5.3 1.6 1 0 0 1 1 1 0 DDHD domain DUF1510 PF07423.6 GAP83567.1 - 0.038 13.3 25.4 0.074 12.4 17.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Strabismus PF06638.6 GAP83567.1 - 0.054 11.7 0.6 0.086 11.1 0.4 1.2 1 0 0 1 1 1 0 Strabismus protein Pox_Ag35 PF03286.9 GAP83567.1 - 0.11 12.0 24.5 0.27 10.7 17.0 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DDRGK PF09756.4 GAP83567.1 - 0.13 11.7 36.6 0.24 10.7 25.4 1.3 1 0 0 1 1 1 0 DDRGK domain Rtf2 PF04641.7 GAP83567.1 - 0.16 11.1 24.5 0.31 10.2 17.0 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger U79_P34 PF03064.11 GAP83567.1 - 0.32 10.4 18.0 0.62 9.5 12.5 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 NARP1 PF12569.3 GAP83567.1 - 0.37 9.4 26.2 0.72 8.5 18.1 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ycf1 PF05758.7 GAP83567.1 - 1.8 6.2 18.9 2.6 5.6 13.1 1.1 1 0 0 1 1 1 0 Ycf1 RRN3 PF05327.6 GAP83567.1 - 2 6.4 9.0 3.4 5.6 6.2 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 MIP-T3 PF10243.4 GAP83567.1 - 2.6 6.4 43.0 4.2 5.7 29.8 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Glycos_transf_2 PF00535.21 GAP83568.1 - 1.7e-22 79.8 0.0 5.2e-22 78.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 GAP83568.1 - 1.8e-09 37.7 0.7 2.6e-06 27.4 0.0 3.1 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 GAP83568.1 - 0.036 14.3 0.0 0.083 13.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 SE PF08491.5 GAP83569.1 - 9.6e-83 277.1 0.0 1.2e-82 276.8 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 GAP83569.1 - 4.7e-10 39.0 0.2 6.8e-07 28.6 0.0 2.3 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAP83569.1 - 1.4e-08 34.0 0.1 1.3e-06 27.5 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAP83569.1 - 0.00035 19.7 0.0 0.0006 18.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 GAP83569.1 - 0.00053 18.9 0.0 0.0015 17.4 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 GAP83569.1 - 0.00072 19.9 0.1 0.002 18.4 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 GAP83569.1 - 0.00078 19.1 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 GAP83569.1 - 0.00099 19.0 0.1 0.0029 17.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAP83569.1 - 0.001 18.9 0.1 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAP83569.1 - 0.0018 17.2 0.2 0.04 12.8 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.2 GAP83569.1 - 0.0027 16.8 0.3 0.016 14.2 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 GAP83569.1 - 0.0027 17.4 0.1 0.0049 16.6 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.17 GAP83569.1 - 0.0029 16.5 0.0 0.014 14.2 0.1 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Shikimate_DH PF01488.15 GAP83569.1 - 0.004 17.2 0.0 0.0068 16.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 GAP83569.1 - 0.0059 16.0 0.1 0.0096 15.3 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 GAP83569.1 - 0.063 11.7 0.1 0.096 11.1 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein ThiF PF00899.16 GAP83569.1 - 0.069 12.9 0.3 0.13 12.1 0.2 1.4 1 0 0 1 1 1 0 ThiF family TPR_7 PF13176.1 GAP83570.1 - 0.011 15.4 0.0 14 5.7 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAP83570.1 - 0.16 12.6 3.5 4.2 8.1 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Trypan_PARP PF05887.6 GAP83570.1 - 0.31 10.8 8.0 0.077 12.8 3.4 1.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) PLRV_ORF5 PF01690.12 GAP83570.1 - 1.9 7.5 18.0 3.6 6.6 12.5 1.4 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Mito_carr PF00153.22 GAP83571.1 - 1.4e-65 217.0 1.7 8.8e-21 73.4 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S24 PF00717.18 GAP83572.1 - 1.3e-06 27.9 0.2 5.2e-06 26.0 0.0 2.0 2 1 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.4 GAP83572.1 - 0.00013 21.4 0.0 0.012 15.1 0.0 2.2 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 EIF_2_alpha PF07541.7 GAP83573.1 - 9.6e-38 128.4 0.0 1.8e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 GAP83573.1 - 2.9e-13 49.7 0.7 5.2e-13 48.8 0.5 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Hemagglutinin PF00509.13 GAP83573.1 - 0.021 12.9 0.1 0.037 12.1 0.1 1.3 1 0 0 1 1 1 0 Haemagglutinin cNMP_binding PF00027.24 GAP83574.1 - 3.8e-39 132.3 0.1 5.2e-17 61.4 0.0 4.6 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Patatin PF01734.17 GAP83574.1 - 5.2e-18 65.7 2.2 2.3e-17 63.5 1.5 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase U79_P34 PF03064.11 GAP83575.1 - 1.7 8.1 12.9 2.1 7.8 8.9 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 UPF0542 PF15086.1 GAP83575.1 - 1.7 8.3 9.0 0.17 11.6 2.0 2.3 1 1 1 2 2 2 0 Uncharacterised protein family UPF0542 DUF2489 PF10675.4 GAP83575.1 - 3.5 7.3 8.1 1.7 8.3 3.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) RD3 PF14473.1 GAP83575.1 - 8 5.9 7.9 30 4.0 5.2 1.9 1 1 1 2 2 2 0 RD3 protein Pyridoxal_deC PF00282.14 GAP83576.1 - 1.4e-115 385.7 0.0 1.7e-115 385.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain HNH_3 PF13392.1 GAP83577.1 - 0.026 13.8 0.1 0.055 12.8 0.1 1.5 1 0 0 1 1 1 0 HNH endonuclease DUF1272 PF06906.6 GAP83577.1 - 0.079 12.8 1.1 0.22 11.4 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) UPF0547 PF10571.4 GAP83577.1 - 4.1 7.1 6.9 0.16 11.7 0.3 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Glyco_hydro_61 PF03443.9 GAP83578.1 - 4.3e-17 62.6 0.0 8.7e-17 61.6 0.0 1.5 1 1 1 2 2 2 1 Glycosyl hydrolase family 61 NACHT PF05729.7 GAP83579.1 - 3.4e-06 26.7 0.0 9e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 GAP83579.1 - 3.8e-06 27.0 0.1 1.4e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAP83579.1 - 0.00034 20.7 0.0 0.0014 18.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_10 PF12846.2 GAP83579.1 - 0.0052 16.2 0.0 0.011 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA-like domain DUF676 PF05057.9 GAP83579.1 - 0.013 14.7 0.0 0.065 12.5 0.0 1.9 2 0 0 2 2 2 0 Putative serine esterase (DUF676) NB-ARC PF00931.17 GAP83579.1 - 0.023 13.5 0.0 0.052 12.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain PGAP1 PF07819.8 GAP83579.1 - 0.028 14.0 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein MMR_HSR1 PF01926.18 GAP83579.1 - 0.058 13.3 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 GAP83579.1 - 0.073 13.3 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Strep_pep PF14404.1 GAP83579.1 - 0.085 13.0 0.2 0.35 11.1 0.2 2.0 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Streptomyces species AAA_29 PF13555.1 GAP83579.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 GAP83579.1 - 0.13 13.1 0.0 0.55 11.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 GAP83579.1 - 0.13 12.7 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein ATP_bind_1 PF03029.12 GAP83579.1 - 0.14 11.6 0.1 0.28 10.6 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 GAP83579.1 - 0.15 11.8 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain DDOST_48kD PF03345.9 GAP83579.1 - 0.2 10.1 0.0 1.1 7.6 0.0 1.9 2 0 0 2 2 2 0 Oligosaccharyltransferase 48 kDa subunit beta cobW PF02492.14 GAP83579.1 - 0.3 10.5 0.0 0.56 9.6 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain KH_1 PF00013.24 GAP83580.1 - 4.6e-40 135.0 5.7 4.7e-16 58.1 0.7 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 GAP83580.1 - 1e-29 101.5 13.6 2.6e-11 42.8 2.8 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 GAP83580.1 - 2.5e-11 42.9 3.3 0.0057 16.1 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 GAP83580.1 - 9.5e-05 21.9 1.0 1.2 8.8 0.1 3.1 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 GAP83580.1 - 0.0016 18.2 6.0 0.83 9.4 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain CENP-K PF11802.3 GAP83581.1 - 9.5e-08 31.5 1.3 0.015 14.5 0.9 2.6 3 0 0 3 3 3 2 Centromere-associated protein K Tropomyosin PF00261.15 GAP83581.1 - 0.025 13.6 9.6 0.06 12.4 3.8 2.3 2 0 0 2 2 2 0 Tropomyosin IncA PF04156.9 GAP83581.1 - 0.22 11.1 9.2 0.21 11.1 1.1 2.7 3 0 0 3 3 3 0 IncA protein Unstab_antitox PF09720.5 GAP83581.1 - 0.52 10.0 3.3 0.59 9.8 0.2 2.6 3 0 0 3 3 3 0 Putative addiction module component Syntaxin_2 PF14523.1 GAP83581.1 - 0.6 10.1 6.4 4.2 7.4 0.7 3.6 3 1 1 4 4 4 0 Syntaxin-like protein Microtub_assoc PF07989.6 GAP83581.1 - 0.65 9.8 7.4 2.4 8.0 0.5 2.8 3 0 0 3 3 3 0 Microtubule associated DUF1664 PF07889.7 GAP83581.1 - 0.9 9.3 3.3 3 7.6 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.2 GAP83581.1 - 2.5 7.9 12.8 14 5.5 5.7 3.0 2 1 1 3 3 3 0 Tropomyosin like DUF2514 PF10721.4 GAP83581.1 - 5.7 6.6 9.5 0.076 12.7 1.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2514) DUF745 PF05335.8 GAP83581.1 - 7.5 6.0 9.1 8.6 5.8 2.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF745) dUTPase PF00692.14 GAP83582.1 - 1.8e-35 121.2 0.0 2.5e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 dUTPase PCNA_N PF00705.13 GAP83583.1 - 7.9e-53 177.3 5.3 1.9e-52 176.1 2.9 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 GAP83583.1 - 3.6e-50 169.1 0.0 6.9e-50 168.2 0.0 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 GAP83583.1 - 5.2e-10 38.8 0.1 6.3e-10 38.6 0.1 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 GAP83583.1 - 1.5e-07 30.4 0.7 3.6e-06 25.9 0.5 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.7 GAP83583.1 - 0.00094 18.2 0.5 0.0076 15.2 0.3 2.4 1 1 0 1 1 1 1 Hus1-like protein Pneumovirus_M2 PF06436.6 GAP83583.1 - 0.014 14.6 0.6 0.23 10.6 0.0 2.4 2 1 1 3 3 3 0 Pneumovirus matrix protein 2 (M2) DNA_pol3_beta_3 PF02768.10 GAP83583.1 - 0.041 13.4 0.2 0.48 9.9 0.0 2.5 2 2 0 2 2 2 0 DNA polymerase III beta subunit, C-terminal domain Vezatin PF12632.2 GAP83584.1 - 2.3e-26 92.3 0.4 3.6e-26 91.7 0.3 1.3 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes NfeD PF01957.13 GAP83584.1 - 0.053 13.6 0.5 0.094 12.8 0.3 1.3 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding Rab5ip PF07019.7 GAP83585.1 - 6.4e-21 74.2 9.4 2e-20 72.6 4.7 2.1 2 0 0 2 2 2 1 Rab5-interacting protein (Rab5ip) GTP_EFTU PF00009.22 GAP83586.1 - 6.6e-09 35.4 0.0 4.5e-08 32.7 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 GAP83586.1 - 0.0076 15.4 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MobB PF03205.9 GAP83586.1 - 0.15 11.7 0.1 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SNARE PF05739.14 GAP83587.1 - 3.6e-07 29.7 4.8 1.3e-06 27.9 0.4 2.6 2 0 0 2 2 2 2 SNARE domain Complex1_LYR_2 PF13233.1 GAP83588.1 - 0.023 15.1 0.0 0.037 14.5 0.0 1.4 1 1 0 1 1 1 0 Complex1_LYR-like Complex1_LYR PF05347.10 GAP83588.1 - 0.038 13.7 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAP83588.1 - 0.094 12.9 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Complex1_LYR-like OB_NTP_bind PF07717.11 GAP83589.1 - 4e-16 58.8 0.0 1.1e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 GAP83589.1 - 2.1e-15 56.5 0.0 4.5e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 GAP83589.1 - 5.4e-12 45.4 0.0 1.4e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAP83589.1 - 1.3e-07 31.2 0.1 1.5e-06 27.8 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAP83589.1 - 0.00055 20.0 0.0 0.002 18.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 GAP83589.1 - 0.014 14.9 0.1 0.06 12.8 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.1 GAP83589.1 - 0.026 14.0 0.0 0.06 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 GAP83589.1 - 0.028 13.3 0.0 0.08 11.8 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.22 GAP83589.1 - 0.14 12.4 0.0 0.42 10.9 0.0 1.8 2 0 0 2 2 2 0 ABC transporter KaiC PF06745.8 GAP83589.1 - 0.15 11.1 0.0 0.39 9.7 0.0 1.6 1 0 0 1 1 1 0 KaiC MaoC_dehydratas PF01575.14 GAP83591.1 - 2.3e-22 78.6 0.0 3.7e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 GAP83591.1 - 8.1e-06 25.6 0.0 0.002 17.9 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase SIC PF03482.8 GAP83591.1 - 0.0047 16.5 0.4 0.0057 16.3 0.3 1.2 1 0 0 1 1 1 1 sic protein CAP_GLY PF01302.20 GAP83592.1 - 1.4e-18 66.3 0.0 2.7e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 GAP83592.1 - 6.3e-17 60.7 3.3 0.00034 20.1 0.0 5.3 3 2 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAP83592.1 - 1.1e-12 47.5 4.1 0.00086 19.0 2.3 4.2 4 1 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 GAP83592.1 - 1.2e-08 33.7 7.9 1.6 9.0 0.0 7.2 7 1 1 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.1 GAP83592.1 - 5.9e-08 31.9 6.4 3.2 8.1 0.0 6.9 6 2 1 7 7 7 2 Leucine Rich repeat LRR_7 PF13504.1 GAP83592.1 - 2.8e-07 29.6 3.2 3.2 8.3 0.0 7.2 7 0 0 7 7 7 1 Leucine rich repeat Fer2_3 PF13085.1 GAP83594.1 - 3e-33 113.9 0.0 4.9e-33 113.2 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.1 GAP83594.1 - 5.8e-09 35.8 4.1 5.8e-09 35.8 2.8 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.1 GAP83594.1 - 6e-09 36.1 5.7 6e-09 36.1 4.0 2.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 GAP83594.1 - 0.00026 21.3 1.6 0.00026 21.3 1.1 2.8 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 GAP83594.1 - 0.00032 20.9 4.1 0.042 14.1 0.4 3.0 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 GAP83594.1 - 0.0012 18.5 7.4 0.0013 18.4 3.2 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 GAP83594.1 - 0.0014 19.0 4.0 0.0014 19.0 2.8 2.4 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 GAP83594.1 - 0.0014 18.3 0.3 0.0014 18.3 0.2 2.4 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain DNA_pol3_tau_4 PF12168.3 GAP83594.1 - 0.4 11.1 2.2 0.29 11.5 0.2 1.8 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer4_15 PF13459.1 GAP83594.1 - 4.2 7.9 7.5 0.67 10.5 0.1 2.6 3 0 0 3 3 3 0 4Fe-4S single cluster domain SpoIIE PF07228.7 GAP83595.1 - 1.6e-12 47.5 0.1 6.5e-12 45.5 0.1 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 GAP83595.1 - 3.2e-11 43.0 0.0 6.4e-11 42.0 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 GAP83595.1 - 1.6e-10 40.8 0.0 0.0003 20.2 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C GPI-anchored PF10342.4 GAP83596.1 - 1.8e-16 60.4 0.6 1.8e-16 60.4 0.4 2.7 2 1 0 2 2 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF605 PF04652.11 GAP83596.1 - 0.12 11.7 15.2 0.14 11.5 10.6 1.1 1 0 0 1 1 1 0 Vta1 like Macoilin PF09726.4 GAP83596.1 - 0.4 8.9 16.5 0.42 8.8 11.4 1.1 1 0 0 1 1 1 0 Transmembrane protein DHHW PF14286.1 GAP83596.1 - 2 7.6 7.6 2.8 7.1 5.2 1.3 1 0 0 1 1 1 0 DHHW protein DUF966 PF06136.8 GAP83596.1 - 3.5 6.9 19.6 4.5 6.5 13.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF1675 PF07897.6 GAP83596.1 - 3.8 7.2 17.6 5.4 6.7 12.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) PIH1 PF08190.7 GAP83596.1 - 7.1 5.9 7.6 9 5.6 5.3 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 CAML PF14963.1 GAP83596.1 - 7.5 5.8 11.2 11 5.3 7.8 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand DUF2146 PF10220.4 GAP83596.1 - 8.3 4.2 7.0 9.8 4.0 4.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DDHD PF02862.12 GAP83596.1 - 9.2 5.9 11.8 12 5.5 8.2 1.2 1 0 0 1 1 1 0 DDHD domain Plasmodium_Vir PF05795.6 GAP83596.1 - 9.8 5.2 7.1 12 4.9 4.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Methyltransf_16 PF10294.4 GAP83597.1 - 0.00063 19.2 0.0 0.017 14.5 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_31 PF13847.1 GAP83597.1 - 0.032 13.8 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 GAP83597.1 - 0.077 13.5 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PQ-loop PF04193.9 GAP83597.1 - 0.099 12.2 0.1 0.26 10.8 0.1 1.7 1 0 0 1 1 1 0 PQ loop repeat Pyr_redox_3 PF13738.1 GAP83598.1 - 1.8e-15 57.5 0.0 4.7e-15 56.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAP83598.1 - 5.3e-06 24.9 0.0 2.4e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 GAP83598.1 - 7e-05 22.7 0.0 0.00023 21.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 GAP83598.1 - 0.00071 18.5 0.0 0.017 14.0 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Ank_2 PF12796.2 GAP83599.1 - 9e-135 439.3 0.0 6.3e-21 74.5 0.0 7.5 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 GAP83599.1 - 7.5e-130 416.8 0.0 3.9e-09 35.8 0.0 14.6 14 0 0 14 14 14 13 Ankyrin repeat Ank_3 PF13606.1 GAP83599.1 - 3.7e-105 333.1 0.0 2.7e-07 30.1 0.0 15.0 14 0 0 14 14 14 13 Ankyrin repeat Ank_5 PF13857.1 GAP83599.1 - 7.4e-93 302.4 2.9 8.4e-10 38.5 0.0 14.1 3 2 11 14 14 14 13 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAP83599.1 - 8.5e-82 268.2 1.3 7.5e-13 48.6 0.0 10.3 4 2 6 10 10 10 10 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 GAP83599.1 - 4.5e-17 61.8 0.2 9.6e-17 60.7 0.0 1.6 2 0 0 2 2 2 1 Phosphorylase superfamily NACHT PF05729.7 GAP83599.1 - 1.8e-06 27.7 0.0 6e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 GAP83599.1 - 6.2e-06 26.3 0.0 0.00017 21.6 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAP83599.1 - 1.7e-05 24.9 0.0 4.8e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 GAP83599.1 - 0.0023 18.0 0.0 0.0058 16.7 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_10 PF12846.2 GAP83599.1 - 0.0033 16.9 0.1 0.0091 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA-like domain KAP_NTPase PF07693.9 GAP83599.1 - 0.026 13.5 0.2 2.9 6.8 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain ABC_tran PF00005.22 GAP83599.1 - 0.027 14.7 0.0 0.066 13.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 GAP83599.1 - 0.045 14.5 0.0 0.16 12.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 GAP83599.1 - 0.053 12.3 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.1 GAP83599.1 - 0.062 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 GAP83599.1 - 0.11 12.3 0.0 0.45 10.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain NUP PF06516.6 GAP83599.1 - 0.11 11.2 0.0 0.27 10.0 0.0 1.5 1 0 0 1 1 1 0 Purine nucleoside permease (NUP) MMR_HSR1 PF01926.18 GAP83599.1 - 0.14 12.1 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.1 GAP83599.1 - 0.14 11.7 0.4 0.33 10.4 0.2 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 GAP83599.1 - 0.19 12.0 0.1 0.19 12.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 GAP83599.1 - 0.2 11.3 0.0 0.4 10.3 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA PF00004.24 GAP83599.1 - 0.21 11.7 0.0 0.53 10.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 GAP83599.1 - 0.41 9.7 0.1 2.1 7.3 0.0 2.1 1 1 1 2 2 2 0 KaiC Cyt-b5 PF00173.23 GAP83600.1 - 7.7e-21 73.6 0.0 1.6e-20 72.6 0.0 1.6 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FMN_dh PF01070.13 GAP83600.1 - 6.2e-18 64.7 5.6 5.3e-12 45.2 0.7 3.2 1 1 2 3 3 3 3 FMN-dependent dehydrogenase DUF3712 PF12505.3 GAP83601.1 - 5.6e-27 94.2 4.8 5.6e-27 94.2 3.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) LEA_2 PF03168.8 GAP83601.1 - 4.2e-05 23.8 0.6 0.0012 19.2 0.0 2.7 2 1 0 2 2 2 1 Late embryogenesis abundant protein FolB PF02152.13 GAP83602.1 - 1.3e-17 63.9 0.0 1.8e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Dihydroneopterin aldolase K_channel_TID PF07941.6 GAP83602.1 - 0.26 11.5 10.1 0.64 10.2 7.0 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Acetyltransf_1 PF00583.19 GAP83603.1 - 1.5e-08 34.5 0.1 2.6e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAP83603.1 - 0.00014 21.9 0.0 0.00032 20.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAP83603.1 - 0.00066 19.7 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAP83603.1 - 0.085 12.6 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein SET PF00856.23 GAP83604.1 - 5.8e-09 36.4 0.0 1e-08 35.6 0.0 1.4 1 0 0 1 1 1 1 SET domain STIL_N PF15253.1 GAP83604.1 - 0.05 12.2 0.0 0.07 11.8 0.0 1.2 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus AAA_13 PF13166.1 GAP83605.1 - 2.9e-05 22.7 13.3 2.9e-05 22.7 9.2 1.5 2 0 0 2 2 2 1 AAA domain Spc7 PF08317.6 GAP83605.1 - 0.00081 18.1 17.2 0.014 14.1 5.5 2.4 1 1 1 2 2 2 2 Spc7 kinetochore protein NPV_P10 PF05531.7 GAP83605.1 - 0.00093 19.4 10.5 1.1 9.5 0.6 4.6 2 1 3 5 5 5 1 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.4 GAP83605.1 - 0.0018 18.1 20.2 0.17 11.7 5.0 3.5 2 1 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF904 PF06005.7 GAP83605.1 - 0.0076 16.5 15.5 2.7 8.3 0.1 4.8 3 1 1 4 4 4 2 Protein of unknown function (DUF904) YlqD PF11068.3 GAP83605.1 - 0.0097 15.9 11.2 1.4 8.9 0.7 3.3 1 1 1 2 2 2 1 YlqD protein Oxysterol_BP PF01237.13 GAP83605.1 - 0.01 14.3 3.9 0.013 13.9 2.7 1.3 1 0 0 1 1 1 0 Oxysterol-binding protein WEMBL PF05701.6 GAP83605.1 - 0.017 13.6 18.6 0.016 13.6 10.4 1.9 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 GAP83605.1 - 0.021 14.0 10.4 0.46 9.6 1.2 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein IFT57 PF10498.4 GAP83605.1 - 0.021 13.5 13.8 0.046 12.4 5.2 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Lebercilin PF15619.1 GAP83605.1 - 0.026 13.9 0.9 0.026 13.9 0.6 3.2 2 1 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Phage_GP20 PF06810.6 GAP83605.1 - 0.036 13.5 12.7 5 6.5 1.9 3.3 3 0 0 3 3 3 0 Phage minor structural protein GP20 DUF972 PF06156.8 GAP83605.1 - 0.073 13.4 19.6 1.1 9.6 0.9 4.3 1 1 3 4 4 4 0 Protein of unknown function (DUF972) Lectin_N PF03954.9 GAP83605.1 - 0.08 12.3 6.5 0.077 12.4 1.2 2.9 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF812 PF05667.6 GAP83605.1 - 0.083 11.3 16.0 0.029 12.9 7.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Filament PF00038.16 GAP83605.1 - 0.19 11.1 20.7 0.072 12.5 1.8 3.8 1 1 3 4 4 4 0 Intermediate filament protein ADIP PF11559.3 GAP83605.1 - 0.35 10.7 22.5 0.74 9.7 0.3 4.1 2 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding MscS_porin PF12795.2 GAP83605.1 - 0.41 9.9 19.4 2 7.6 9.3 3.0 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain Mnd1 PF03962.10 GAP83605.1 - 0.47 10.0 19.0 0.17 11.5 3.4 3.6 2 1 2 4 4 4 0 Mnd1 family DUF1664 PF07889.7 GAP83605.1 - 0.52 10.1 11.9 0.23 11.2 0.3 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) MCPsignal PF00015.16 GAP83605.1 - 0.63 9.5 11.4 0.33 10.4 1.4 2.4 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Lipoprotein_7 PF01540.11 GAP83605.1 - 0.74 8.8 10.4 0.39 9.7 3.7 2.3 1 1 2 3 3 3 0 Adhesin lipoprotein FlaC_arch PF05377.6 GAP83605.1 - 1.1 9.2 15.6 1.4 8.8 0.3 5.4 3 2 2 5 5 5 0 Flagella accessory protein C (FlaC) IncA PF04156.9 GAP83605.1 - 1.1 8.8 19.3 2.7 7.5 0.1 2.8 1 1 0 2 2 2 0 IncA protein TMF_TATA_bd PF12325.3 GAP83605.1 - 1.3 8.7 18.1 2.2 8.0 1.4 3.7 2 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.7 GAP83605.1 - 1.4 8.6 18.8 37 4.0 8.5 3.2 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein GAS PF13851.1 GAP83605.1 - 1.5 7.9 17.7 2.2 7.4 9.5 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Spectrin PF00435.16 GAP83605.1 - 1.7 8.9 16.0 2.8 8.2 0.1 3.7 2 1 2 4 4 4 0 Spectrin repeat GSH_synthase PF03199.10 GAP83605.1 - 1.9 8.6 5.0 2.2 8.4 0.4 3.0 2 1 1 3 3 3 0 Eukaryotic glutathione synthase SlyX PF04102.7 GAP83605.1 - 2.1 8.7 10.6 2.3 8.6 0.1 4.5 2 1 3 5 5 4 0 SlyX COG2 PF06148.6 GAP83605.1 - 2.2 8.1 13.7 0.24 11.2 1.2 3.4 2 1 2 4 4 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TBPIP PF07106.8 GAP83605.1 - 3.3 7.2 21.0 1 8.8 3.9 4.0 2 1 1 4 4 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Atg14 PF10186.4 GAP83605.1 - 4.8 6.0 17.8 6 5.7 6.0 2.7 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 GAP83605.1 - 5.3 6.9 18.7 25 4.7 0.6 4.5 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding FliJ PF02050.11 GAP83605.1 - 6 6.9 16.3 6.9 6.7 1.8 3.9 2 1 2 4 4 4 0 Flagellar FliJ protein WXG100 PF06013.7 GAP83605.1 - 6.2 6.8 6.8 27 4.8 0.0 3.9 4 1 0 4 4 3 0 Proteins of 100 residues with WXG FemAB PF02388.11 GAP83605.1 - 7.7 5.0 10.9 0.52 8.9 1.4 2.5 2 1 1 3 3 3 0 FemAB family Prefoldin PF02996.12 GAP83605.1 - 8.9 5.9 14.0 19 4.9 0.1 4.4 3 2 1 4 4 4 0 Prefoldin subunit Syntaxin-6_N PF09177.6 GAP83605.1 - 8.9 6.7 14.0 7.8 6.9 3.7 3.2 2 1 1 3 3 3 0 Syntaxin 6, N-terminal RNase_T PF00929.19 GAP83606.1 - 2.4e-23 83.2 0.0 4e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Exonuclease TPR_11 PF13414.1 GAP83607.1 - 1.3e-24 85.6 7.2 4.8e-10 38.9 0.5 4.4 2 2 3 5 5 5 5 TPR repeat TPR_1 PF00515.23 GAP83607.1 - 2.9e-22 77.2 2.1 4.7e-07 29.1 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 GAP83607.1 - 1.1e-20 71.8 4.7 2.6e-05 23.8 0.1 6.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 GAP83607.1 - 1.9e-13 49.7 6.9 0.0019 18.6 0.5 6.1 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 GAP83607.1 - 3.9e-13 48.4 2.0 0.0047 17.0 0.0 5.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAP83607.1 - 1.9e-12 47.4 5.5 6.7e-05 23.4 0.1 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 GAP83607.1 - 6.6e-12 45.5 6.2 0.00022 21.5 1.9 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAP83607.1 - 6.8e-12 45.1 5.4 7.3e-08 32.2 0.2 4.2 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAP83607.1 - 1.4e-10 40.8 1.2 0.002 17.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAP83607.1 - 1.1e-08 34.2 6.9 0.0032 17.1 0.1 6.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAP83607.1 - 1.2e-08 34.1 0.7 0.00097 18.7 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat Apc3 PF12895.2 GAP83607.1 - 8.4e-07 29.0 2.8 0.0024 17.9 0.3 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 GAP83607.1 - 1.6e-06 28.1 3.6 0.43 11.1 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_20 PF14561.1 GAP83607.1 - 7.2e-06 26.0 7.1 0.25 11.4 0.0 4.6 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_3 PF07720.7 GAP83607.1 - 0.016 15.0 0.0 6.5 6.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 GAP83607.1 - 0.025 14.4 6.1 0.98 9.4 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Death PF00531.17 GAP83607.1 - 0.062 13.0 0.8 3.4 7.4 0.0 3.5 2 1 1 3 3 3 0 Death domain MIT PF04212.13 GAP83607.1 - 0.084 12.7 5.4 5.8 6.8 0.7 4.5 3 1 1 4 4 3 0 MIT (microtubule interacting and transport) domain DUF1641 PF07849.6 GAP83607.1 - 0.12 12.0 0.4 0.36 10.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) RRM_1 PF00076.17 GAP83608.1 - 1.7e-36 123.6 0.0 2.9e-18 65.2 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP83608.1 - 1.3e-29 101.9 0.0 4.3e-14 52.2 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP83608.1 - 9.8e-21 73.3 0.0 2.3e-12 46.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 GAP83608.1 - 0.003 17.2 0.1 0.076 12.7 0.0 2.3 1 1 1 2 2 2 1 Limkain b1 RRM_3 PF08777.6 GAP83608.1 - 0.014 15.1 0.0 0.56 10.0 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif Nup35_RRM_2 PF14605.1 GAP83608.1 - 0.025 14.3 0.0 0.054 13.2 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif HLH PF00010.21 GAP83609.1 - 2.4e-12 46.3 2.5 4.6e-12 45.4 1.0 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF904 PF06005.7 GAP83609.1 - 0.0044 17.2 0.1 0.0044 17.2 0.1 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF904) TMF_DNA_bd PF12329.3 GAP83609.1 - 0.15 11.8 0.8 0.33 10.7 0.1 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding NifQ PF04891.7 GAP83609.1 - 0.51 10.4 2.9 0.96 9.5 2.0 1.4 1 0 0 1 1 1 0 NifQ RepA_C PF04796.7 GAP83610.1 - 0.029 13.9 0.0 0.036 13.6 0.0 1.1 1 0 0 1 1 1 0 Plasmid encoded RepA protein Zn_clus PF00172.13 GAP83611.1 - 1.2e-07 31.4 13.5 2.4e-07 30.5 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain THOC7 PF05615.8 GAP83612.1 - 0.01 16.0 4.9 0.01 16.0 3.4 2.5 2 0 0 2 2 2 0 Tho complex subunit 7 Tropomyosin_1 PF12718.2 GAP83612.1 - 5.1 6.9 19.0 1.9 8.3 1.0 2.7 2 1 0 2 2 2 0 Tropomyosin like Fungal_trans PF04082.13 GAP83613.1 - 5.6e-29 100.8 0.0 9e-29 100.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP83613.1 - 3.1e-07 30.1 12.6 5.3e-07 29.4 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ThiF PF00899.16 GAP83614.1 - 6.3e-10 38.9 0.0 1.6e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 ThiF family DUF2633 PF11119.3 GAP83614.1 - 0.1 12.3 0.1 0.86 9.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) PAPS_reduct PF01507.14 GAP83614.1 - 0.11 12.2 0.0 2 8.2 0.0 2.5 3 0 0 3 3 3 0 Phosphoadenosine phosphosulfate reductase family MFS_1 PF07690.11 GAP83616.1 - 7.4e-41 140.0 44.3 3.4e-39 134.5 31.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP83616.1 - 4.4e-15 55.2 11.7 4.4e-15 55.2 8.1 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 GAP83616.1 - 6.2e-05 21.3 20.4 0.00011 20.5 14.1 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 GAP83616.1 - 0.00011 20.4 4.8 0.00011 20.4 3.3 2.7 2 1 0 3 3 3 1 Transmembrane secretion effector Pox_A14 PF05767.7 GAP83616.1 - 0.028 14.3 0.0 0.028 14.3 0.0 3.1 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 Anp1 PF03452.9 GAP83617.1 - 9.6e-122 405.3 0.9 1.9e-121 404.3 0.0 1.7 2 0 0 2 2 2 1 Anp1 DUF2146 PF10220.4 GAP83617.1 - 2.1 6.2 10.4 2.9 5.7 7.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Sec7 PF01369.15 GAP83618.1 - 2.5e-57 193.6 0.0 4.5e-57 192.7 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 GAP83618.1 - 2e-21 76.1 0.3 5.3e-12 45.5 0.0 3.9 4 0 0 4 4 4 3 Guanine nucleotide exchange factor in Golgi transport N-terminal SGL PF08450.7 GAP83619.1 - 0.00041 19.7 0.1 0.0086 15.4 0.1 2.1 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Kelch_3 PF13415.1 GAP83619.1 - 0.078 13.1 0.7 2.9 8.1 0.0 3.1 4 0 0 4 4 4 0 Galactose oxidase, central domain bZIP_1 PF00170.16 GAP83620.1 - 6.3e-10 38.8 10.6 6.3e-10 38.8 7.4 2.3 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 GAP83620.1 - 4.1e-05 23.3 9.4 4.1e-05 23.3 6.5 2.7 2 1 0 2 2 2 1 Basic region leucine zipper BAF1_ABF1 PF04684.8 GAP83620.1 - 4.6 5.9 12.9 7.5 5.2 8.9 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor adh_short PF00106.20 GAP83623.1 - 1e-14 54.7 0.1 4.8e-14 52.6 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP83623.1 - 2.6e-06 27.2 0.0 1.3e-05 24.9 0.0 2.0 2 1 1 3 3 3 1 KR domain Epimerase PF01370.16 GAP83623.1 - 2.4e-05 23.8 0.0 0.00073 19.0 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 GAP83623.1 - 0.093 12.4 0.0 0.11 12.2 0.0 1.3 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 GAP83623.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Fungal_trans_2 PF11951.3 GAP83624.1 - 1.2e-30 106.3 0.6 1e-18 67.1 0.3 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP83624.1 - 2.8e-08 33.5 6.4 4.8e-08 32.7 4.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SEN1_N PF12726.2 GAP83624.1 - 0.14 10.1 0.0 0.21 9.5 0.0 1.1 1 0 0 1 1 1 0 SEN1 N terminal Ribosomal_L44 PF00935.14 GAP83626.1 - 1.8e-34 117.6 10.4 2.4e-34 117.1 7.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 zf-RanBP PF00641.13 GAP83626.1 - 0.052 12.6 0.3 0.098 11.7 0.2 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Ribosomal_L33 PF00471.15 GAP83626.1 - 0.51 10.6 5.6 0.57 10.4 0.3 2.6 2 1 0 2 2 2 0 Ribosomal protein L33 CIAPIN1 PF05093.8 GAP83627.1 - 2.9e-34 117.1 1.1 5.3e-34 116.2 0.8 1.4 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis RdRP PF05183.7 GAP83628.1 - 1.2e-129 433.7 0.0 1.8e-129 433.1 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase AAA_12 PF13087.1 GAP83628.1 - 7.7e-50 169.0 0.0 1.2e-49 168.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAP83628.1 - 5.1e-44 150.6 1.3 3.4e-42 144.6 0.9 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAP83628.1 - 4e-14 52.1 0.2 1e-12 47.6 0.1 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 GAP83628.1 - 5.4e-12 45.7 0.1 2.3e-11 43.6 0.0 2.1 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.13 GAP83628.1 - 2.1e-06 27.4 0.1 0.0036 16.8 0.0 3.3 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 GAP83628.1 - 2.6e-06 27.4 0.0 9e-06 25.6 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 GAP83628.1 - 1.3e-05 24.7 0.0 5.2e-05 22.8 0.0 2.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.11 GAP83628.1 - 5.2e-05 22.5 0.1 0.00018 20.7 0.0 1.9 1 1 0 1 1 1 1 PhoH-like protein Helicase_RecD PF05127.9 GAP83628.1 - 0.0002 21.0 0.0 0.00065 19.3 0.0 1.9 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.16 GAP83628.1 - 0.0015 17.8 0.1 0.0049 16.2 0.1 1.9 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Flavi_DEAD PF07652.9 GAP83628.1 - 0.0025 17.5 0.3 1 9.1 0.1 2.7 1 1 1 2 2 2 1 Flavivirus DEAD domain UvrD_C_2 PF13538.1 GAP83628.1 - 0.0055 16.8 0.1 0.019 15.1 0.0 2.0 2 0 0 2 2 1 1 UvrD-like helicase C-terminal domain AAA PF00004.24 GAP83628.1 - 0.042 14.0 0.3 0.15 12.2 0.2 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAP83628.1 - 0.11 12.6 0.1 1.2 9.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.4 GAP83628.1 - 0.12 11.3 0.2 2.4 7.0 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 GAP83629.1 - 1.2e-29 103.4 0.1 1.5e-29 103.0 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAP83629.1 - 2.5e-07 30.8 0.8 5.4e-07 29.7 0.4 1.6 1 1 1 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.18 GAP83629.1 - 0.00043 20.1 0.0 0.00062 19.6 0.0 1.3 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 GAP83629.1 - 0.0023 17.8 0.0 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF2742 PF10888.3 GAP83629.1 - 0.0025 17.7 0.8 0.0061 16.4 0.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2742) Miro PF08477.8 GAP83629.1 - 0.0052 17.2 0.0 0.011 16.2 0.0 1.6 2 0 0 2 2 1 1 Miro-like protein T2SE PF00437.15 GAP83629.1 - 0.0071 15.2 0.1 0.027 13.3 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein Thymidylate_kin PF02223.12 GAP83629.1 - 0.012 15.0 0.0 0.039 13.3 0.0 1.7 2 0 0 2 2 2 0 Thymidylate kinase AAA_19 PF13245.1 GAP83629.1 - 0.017 14.8 0.8 0.017 14.8 0.5 2.9 3 1 0 3 3 3 0 Part of AAA domain GTP_EFTU PF00009.22 GAP83629.1 - 0.03 13.7 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_32 PF13654.1 GAP83629.1 - 0.03 12.9 0.0 0.055 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAP83629.1 - 0.039 14.0 0.0 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 GAP83629.1 - 0.058 12.3 0.0 0.085 11.8 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_17 PF13207.1 GAP83629.1 - 0.077 13.8 0.5 0.39 11.5 0.4 2.2 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 GAP83629.1 - 0.081 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 GAP83629.1 - 0.098 12.1 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 GAP83629.1 - 0.17 12.0 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase RHD3 PF05879.7 GAP83629.1 - 0.17 9.7 0.0 0.23 9.3 0.0 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) Pyr_redox_3 PF13738.1 GAP83631.1 - 5.4e-24 85.3 0.0 8e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAP83631.1 - 2.3e-11 43.7 0.0 1.7e-09 37.6 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 GAP83631.1 - 0.00087 18.3 0.0 0.012 14.5 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAP83631.1 - 0.0013 18.6 0.1 1.3 8.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Frag1 PF10277.4 GAP83633.1 - 5.4e-12 45.6 3.3 6.7e-12 45.3 2.3 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Herpes_BMRF2 PF04633.7 GAP83633.1 - 0.014 14.3 2.0 0.021 13.7 1.4 1.3 1 0 0 1 1 1 0 Herpesvirus BMRF2 protein Pox_A14 PF05767.7 GAP83633.1 - 0.053 13.4 0.7 0.085 12.8 0.3 1.6 1 1 0 1 1 1 0 Poxvirus virion envelope protein A14 Sugar_tr PF00083.19 GAP83634.1 - 8e-65 219.1 21.5 1.6e-63 214.8 14.9 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP83634.1 - 1.3e-15 56.9 32.4 5.7e-15 54.8 16.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Baculo_PEP_C PF04513.7 GAP83635.1 - 9.4e-06 25.5 0.3 0.0014 18.4 0.0 2.1 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_DNA_bd PF12329.3 GAP83635.1 - 2.5e-05 23.9 0.0 0.00015 21.4 0.0 2.1 1 1 0 1 1 1 1 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.7 GAP83635.1 - 3.8e-05 23.8 0.8 0.00072 19.7 0.1 2.8 1 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.4 GAP83635.1 - 4.1e-05 23.6 0.1 0.0015 18.6 0.1 2.6 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.7 GAP83635.1 - 9.4e-05 22.2 0.1 0.00053 19.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) PspA_IM30 PF04012.7 GAP83635.1 - 0.001 18.4 0.6 0.0027 17.0 0.1 1.8 2 1 0 2 2 2 1 PspA/IM30 family Tropomyosin_1 PF12718.2 GAP83635.1 - 0.0015 18.3 0.1 0.01 15.6 0.0 2.1 2 1 0 2 2 2 1 Tropomyosin like Osmo_CC PF08946.5 GAP83635.1 - 0.0018 18.2 2.1 0.38 10.8 0.3 3.2 2 1 1 3 3 2 1 Osmosensory transporter coiled coil CENP-F_leu_zip PF10473.4 GAP83635.1 - 0.0019 18.0 0.1 0.0032 17.3 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MbeB_N PF04837.7 GAP83635.1 - 0.0021 18.1 0.1 0.0065 16.5 0.0 1.9 2 0 0 2 2 1 1 MbeB-like, N-term conserved region MbeD_MobD PF04899.7 GAP83635.1 - 0.0022 17.8 1.4 0.13 12.1 0.1 3.0 2 1 1 3 3 3 1 MbeD/MobD like SlyX PF04102.7 GAP83635.1 - 0.0028 17.9 0.3 0.0083 16.4 0.1 1.9 2 0 0 2 2 2 1 SlyX Laminin_II PF06009.7 GAP83635.1 - 0.0031 17.2 0.1 0.01 15.6 0.0 1.7 2 0 0 2 2 2 1 Laminin Domain II TelA PF05816.6 GAP83635.1 - 0.0049 15.6 0.8 0.0098 14.6 0.1 1.7 2 0 0 2 2 2 1 Toxic anion resistance protein (TelA) DUF4164 PF13747.1 GAP83635.1 - 0.0065 16.5 0.7 0.31 11.1 0.0 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF4164) Cep57_CLD PF14073.1 GAP83635.1 - 0.009 15.8 0.1 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 Gp58 PF07902.6 GAP83635.1 - 0.013 13.7 0.3 0.031 12.4 0.0 1.6 2 0 0 2 2 2 0 gp58-like protein Reo_sigmaC PF04582.7 GAP83635.1 - 0.016 14.4 0.0 0.02 14.0 0.0 1.2 1 1 0 1 1 1 0 Reovirus sigma C capsid protein FlaC_arch PF05377.6 GAP83635.1 - 0.016 15.0 0.0 0.17 11.7 0.0 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) ADIP PF11559.3 GAP83635.1 - 0.016 15.0 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding XhlA PF10779.4 GAP83635.1 - 0.023 14.5 0.8 0.067 13.1 0.1 2.1 2 1 1 3 3 2 0 Haemolysin XhlA AAA_13 PF13166.1 GAP83635.1 - 0.026 13.0 0.0 0.038 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain bZIP_1 PF00170.16 GAP83635.1 - 0.027 14.4 0.1 0.46 10.4 0.0 2.3 1 1 1 2 2 2 0 bZIP transcription factor Tropomyosin PF00261.15 GAP83635.1 - 0.029 13.4 0.0 0.049 12.7 0.0 1.3 1 0 0 1 1 1 0 Tropomyosin DUF948 PF06103.6 GAP83635.1 - 0.036 13.9 0.2 0.61 9.9 0.0 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3552 PF12072.3 GAP83635.1 - 0.067 12.3 0.2 0.16 11.1 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DUF724 PF05266.9 GAP83635.1 - 0.076 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TMCO5 PF14992.1 GAP83635.1 - 0.088 11.9 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 TMCO5 family Myosin_tail_1 PF01576.14 GAP83635.1 - 0.099 10.3 0.1 0.13 9.9 0.1 1.1 1 0 0 1 1 1 0 Myosin tail DivIVA PF05103.8 GAP83635.1 - 0.1 12.6 0.0 15 5.6 0.0 2.3 2 0 0 2 2 2 0 DivIVA protein Surfac_D-trimer PF09006.6 GAP83635.1 - 0.11 12.2 1.0 1.6 8.4 0.1 2.7 1 1 1 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation DUF16 PF01519.11 GAP83635.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 Dynamitin PF04912.9 GAP83635.1 - 0.12 11.1 0.3 0.32 9.7 0.2 1.9 1 1 0 1 1 1 0 Dynamitin GAS PF13851.1 GAP83635.1 - 0.13 11.4 0.4 0.84 8.7 0.0 2.1 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding H-kinase_dim PF02895.9 GAP83635.1 - 0.17 12.2 2.4 2 8.8 1.6 2.6 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain DUF904 PF06005.7 GAP83635.1 - 0.19 12.0 1.4 0.9 9.8 0.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 GAP83635.1 - 0.37 10.6 3.6 2.9 7.8 0.4 2.7 2 1 1 3 3 2 0 Basic region leucine zipper Amidase PF01425.16 GAP83637.1 - 5.6e-65 219.9 0.0 7.2e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 Amidase Glyco_tranf_2_2 PF10111.4 GAP83640.1 - 0.13 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Ded_cyto PF06920.8 GAP83641.1 - 1e-13 51.0 0.2 4.7e-13 48.8 0.2 2.0 2 0 0 2 2 2 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 GAP83641.1 - 5.3e-12 45.7 0.0 1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_1 PF00018.23 GAP83641.1 - 2.9e-05 23.3 0.0 6.6e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAP83641.1 - 0.00011 21.7 0.2 0.00029 20.3 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain zf-CpG_bind_C PF12269.3 GAP83641.1 - 0.51 9.7 0.4 0.95 8.8 0.3 1.3 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain zf-C2H2_4 PF13894.1 GAP83642.1 - 0.11 12.9 7.7 0.05 13.9 1.3 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger Ufd2P_core PF10408.4 GAP83643.1 - 5.9e-190 632.6 3.0 7.5e-190 632.3 2.1 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 GAP83643.1 - 8.4e-20 70.5 1.4 3.3e-19 68.5 1.0 2.1 1 0 0 1 1 1 1 U-box domain V-SNARE PF05008.10 GAP83643.1 - 0.00089 19.3 2.8 0.057 13.5 0.0 3.8 4 0 0 4 4 4 1 Vesicle transport v-SNARE protein N-terminus Rubella_Capsid PF05750.6 GAP83643.1 - 0.038 13.3 3.8 0.066 12.5 2.7 1.3 1 0 0 1 1 1 0 Rubella capsid protein Epimerase PF01370.16 GAP83645.1 - 2.9e-15 56.3 0.0 4e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAP83645.1 - 1.3e-12 47.0 0.0 2.2e-12 46.2 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAP83645.1 - 6.6e-11 42.5 0.0 1e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAP83645.1 - 8.7e-09 34.6 0.2 8e-08 31.5 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 GAP83645.1 - 7.5e-07 29.2 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 GAP83645.1 - 3.3e-05 22.9 0.0 4.5e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 GAP83645.1 - 0.0017 18.0 0.0 0.0037 16.9 0.0 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 GAP83645.1 - 0.021 14.0 0.2 0.037 13.2 0.2 1.4 1 1 0 1 1 1 0 NmrA-like family zf-C2H2 PF00096.21 GAP83647.1 - 1.1e-17 63.1 30.0 6.2e-05 23.1 0.5 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAP83647.1 - 2.9e-15 55.6 36.1 3.5e-07 30.1 1.3 5.2 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAP83647.1 - 1.6e-06 27.9 35.8 0.00043 20.4 0.5 4.9 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAP83647.1 - 0.00017 21.5 3.3 2.6 8.3 0.0 3.9 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAP83647.1 - 0.0049 17.0 8.2 0.2 11.9 0.1 4.6 4 0 0 4 4 4 1 Zinc-finger of C2H2 type MFS_1 PF07690.11 GAP83648.1 - 6.7e-20 71.1 39.6 6.5e-19 67.8 23.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAP83648.1 - 0.00067 18.1 10.3 0.00067 18.1 7.1 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein DUF3938 PF13074.1 GAP83648.1 - 0.016 15.0 0.2 0.042 13.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) DUF2811 PF10929.3 GAP83648.1 - 0.092 12.7 0.2 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) Sugar_tr PF00083.19 GAP83648.1 - 0.31 9.5 23.3 4.1 5.8 16.2 2.5 1 1 0 1 1 1 0 Sugar (and other) transporter DUF1469 PF07332.6 GAP83648.1 - 0.68 9.6 0.0 0.68 9.6 0.0 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1469) Mito_carr PF00153.22 GAP83649.1 - 2.7e-46 155.2 10.1 1e-16 60.4 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Dioxygenase_C PF00775.16 GAP83651.1 - 2e-10 40.2 0.1 3.3e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase DUF2763 PF10961.3 GAP83651.1 - 0.014 15.7 0.7 0.051 13.9 0.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) adh_short PF00106.20 GAP83652.1 - 5.4e-26 91.4 5.2 7.7e-18 64.9 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 GAP83652.1 - 2.1e-23 83.3 1.6 1.2e-14 54.6 0.8 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP83652.1 - 2.9e-10 40.1 3.3 1.2e-08 34.7 0.0 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.16 GAP83652.1 - 0.00079 18.9 0.0 0.6 9.4 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Glyco_hydro_12 PF01670.11 GAP83653.1 - 8.9e-35 119.7 2.3 8.9e-35 119.7 1.6 1.8 1 1 1 2 2 2 1 Glycosyl hydrolase family 12 Fimbrial_PilY2 PF14481.1 GAP83653.1 - 0.031 13.6 0.3 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 Type 4 fimbrial biogenesis protein PilY2 LRR_1 PF00560.28 GAP83654.1 - 0.007 16.2 1.6 25 5.4 0.1 4.4 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_7 PF13504.1 GAP83654.1 - 0.038 14.1 1.2 45 4.8 0.1 4.7 4 0 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 GAP83654.1 - 0.051 13.6 3.3 2.3 8.5 0.1 3.4 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.2 GAP83654.1 - 0.1 12.2 0.1 8.8 6.0 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) zf-C2H2 PF00096.21 GAP83655.1 - 0.0095 16.2 0.3 0.022 15.1 0.2 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP83655.1 - 0.015 15.6 0.5 0.036 14.4 0.4 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Hexapep PF00132.19 GAP83656.1 - 8.7e-09 34.4 0.1 0.0047 16.3 0.0 2.8 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 GAP83656.1 - 0.012 15.6 0.0 0.027 14.5 0.0 1.6 1 1 0 1 1 1 0 MobA-like NTP transferase domain Hexapep_2 PF14602.1 GAP83656.1 - 0.014 14.9 7.1 12 5.5 0.7 3.9 2 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase HIG_1_N PF04588.8 GAP83657.1 - 0.066 12.9 0.3 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Hypoxia induced protein conserved region Spt20 PF12090.3 GAP83658.1 - 1.1e-41 142.1 0.0 1.1e-41 142.1 0.0 3.8 2 1 0 2 2 2 1 Spt20 family AAA_23 PF13476.1 GAP83658.1 - 3.8 7.7 32.6 6.9 6.9 22.6 1.4 1 0 0 1 1 1 0 AAA domain ATG27 PF09451.5 GAP83661.1 - 6.2e-70 235.4 4.3 7.6e-69 231.9 3.0 1.9 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 GAP83661.1 - 0.015 15.0 0.1 5.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Cation-independent mannose-6-phosphate receptor repeat CobT PF06213.7 GAP83661.1 - 0.99 8.4 6.6 1.6 7.8 4.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Coprogen_oxidas PF01218.13 GAP83662.1 - 1.1e-133 444.3 0.0 1.4e-133 444.0 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Trp_oprn_chp PF09534.5 GAP83662.1 - 0.01 15.4 0.0 0.049 13.2 0.1 1.8 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Peptidase_C12 PF01088.16 GAP83663.1 - 6e-40 136.7 0.0 1.2e-31 109.5 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 bZIP_1 PF00170.16 GAP83664.1 - 5.9e-08 32.5 8.4 7.8e-08 32.1 5.8 1.1 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAP83664.1 - 0.00011 21.9 14.6 0.00027 20.6 8.6 2.0 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.12 GAP83664.1 - 0.0015 18.7 4.6 0.0021 18.2 3.2 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor MCC-bdg_PDZ PF10506.4 GAP83664.1 - 0.0044 16.8 1.5 0.0044 16.8 1.0 1.8 1 1 1 2 2 2 1 PDZ domain of MCC-2 bdg protein for Usher syndrome PBP_sp32 PF07222.7 GAP83664.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Takusan PF04822.8 GAP83664.1 - 0.18 11.5 2.6 0.3 10.8 1.8 1.3 1 0 0 1 1 1 0 Takusan Clat_adaptor_s PF01217.15 GAP83665.1 - 1.4e-44 151.2 0.0 2.4e-44 150.4 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Mito_fiss_reg PF05308.6 GAP83666.1 - 0.064 12.6 8.3 0.075 12.3 5.8 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 GAP83666.1 - 2.5 7.3 11.7 2.8 7.1 8.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-CSL PF05207.8 GAP83668.1 - 3.8e-15 55.1 0.1 4.1e-15 55.0 0.1 1.2 1 0 0 1 1 1 1 CSL zinc finger ABC_membrane_2 PF06472.10 GAP83669.1 - 2.8e-107 358.0 0.4 2.8e-107 358.0 0.3 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 GAP83669.1 - 1.5e-17 64.2 0.0 3.1e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAP83669.1 - 0.00062 19.8 0.0 0.0018 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAP83669.1 - 0.012 15.6 0.3 0.042 13.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 GAP83669.1 - 0.034 13.6 0.0 0.078 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 GAP83669.1 - 0.045 14.0 0.2 0.21 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 GAP83669.1 - 0.074 12.2 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SMC_N PF02463.14 GAP83669.1 - 0.095 11.9 0.0 0.22 10.7 0.0 1.6 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.16 GAP83669.1 - 0.14 11.2 0.1 0.42 9.7 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TRAM1 PF08390.6 GAP83670.1 - 0.048 13.1 2.6 0.099 12.1 1.8 1.4 1 0 0 1 1 1 0 TRAM1-like protein DUF2818 PF10993.3 GAP83670.1 - 0.34 11.4 3.3 1.1 9.7 2.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2818) HET PF06985.6 GAP83671.1 - 0.00036 20.7 0.6 0.04 14.0 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HET PF06985.6 GAP83672.1 - 2e-05 24.7 0.9 0.0025 17.9 0.6 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 GAP83674.1 - 3.1e-39 134.6 53.4 1.2e-32 113.0 23.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP83674.1 - 1.5e-38 132.5 21.1 2.7e-38 131.7 14.7 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter ATG22 PF11700.3 GAP83674.1 - 1.9e-08 33.2 13.7 1.5e-06 26.9 1.6 2.3 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like HTH_38 PF13936.1 GAP83674.1 - 0.00069 19.1 0.2 0.0025 17.3 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain DUF791 PF05631.9 GAP83674.1 - 0.0043 15.8 0.9 0.05 12.2 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF791) Esterase_phd PF10503.4 GAP83675.1 - 3.4e-21 75.5 0.8 5.5e-21 74.8 0.5 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 GAP83675.1 - 1.4e-12 47.2 2.1 2e-12 46.7 1.4 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAP83675.1 - 7e-05 22.6 0.3 0.00011 22.0 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 GAP83675.1 - 0.00057 18.7 2.3 0.00095 17.9 1.6 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 GAP83675.1 - 0.0031 17.4 0.1 0.0055 16.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 GAP83675.1 - 0.0096 15.5 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold AIP3 PF03915.8 GAP83676.1 - 7e-158 525.9 12.8 1.1e-157 525.3 8.9 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 Lectin_N PF03954.9 GAP83676.1 - 0.0056 16.0 0.2 0.0056 16.0 0.1 3.3 4 0 0 4 4 4 1 Hepatic lectin, N-terminal domain FliL PF03748.9 GAP83676.1 - 0.024 14.6 0.2 0.024 14.6 0.2 3.1 3 0 0 3 3 3 0 Flagellar basal body-associated protein FliL GNVR PF13807.1 GAP83676.1 - 0.15 11.7 1.7 0.75 9.5 0.2 2.5 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase DUF1664 PF07889.7 GAP83676.1 - 0.29 10.9 12.9 0.62 9.8 0.1 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 GAP83676.1 - 0.74 10.1 10.8 0.14 12.4 0.4 4.2 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein P120R PF08062.6 GAP83676.1 - 2.3 8.6 7.4 8.6 6.8 5.1 2.0 1 0 0 1 1 1 0 P120R (NUC006) repeat LsmAD PF06741.8 GAP83677.1 - 5.4e-24 84.0 3.5 5.4e-24 84.0 2.4 2.4 2 0 0 2 2 2 1 LsmAD domain DUF677 PF05055.7 GAP83677.1 - 0.12 11.0 0.1 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DUF605 PF04652.11 GAP83678.1 - 0.7 9.2 16.8 1.2 8.4 11.6 1.3 1 0 0 1 1 1 0 Vta1 like DUF3408 PF11888.3 GAP83679.1 - 0.013 15.3 1.8 0.67 9.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3408) BRO1 PF03097.13 GAP83680.1 - 3.6e-111 371.5 0.0 5.4e-111 370.9 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 GAP83680.1 - 9.4e-74 248.0 3.9 1.9e-73 247.0 2.7 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Fringe PF02434.11 GAP83681.1 - 5.3e-09 35.6 0.0 8.8e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.7 GAP83681.1 - 6.6e-09 35.3 0.1 8.4e-07 28.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF604 2-oxoacid_dh PF00198.18 GAP83682.1 - 0.017 14.4 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) HMGL-like PF00682.14 GAP83683.1 - 5.8e-40 137.4 0.1 2.8e-39 135.1 0.0 1.8 1 1 0 1 1 1 1 HMGL-like ATP-synt_ab PF00006.20 GAP83684.1 - 2.6e-60 203.6 0.0 3.5e-60 203.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 GAP83684.1 - 5.7e-17 62.2 0.1 1.1e-16 61.3 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 GAP83684.1 - 6.1e-10 39.1 0.5 1.2e-09 38.2 0.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 GAP83684.1 - 0.0032 17.3 0.4 0.0066 16.3 0.3 1.5 1 0 0 1 1 1 1 HAS barrel domain Aldose_epim PF01263.15 GAP83685.1 - 2e-47 161.7 0.7 2.7e-47 161.3 0.5 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Period_C PF12114.3 GAP83686.1 - 2.5 7.6 10.0 4.5 6.8 7.0 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Herpes_capsid PF06112.6 GAP83686.1 - 7.6 6.5 12.1 21 5.1 8.4 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Methyltransf_3 PF01596.12 GAP83687.1 - 2.2e-28 98.7 0.0 2.7e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 GAP83687.1 - 1.3e-09 38.8 0.1 2.4e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP83687.1 - 2.5e-05 24.2 0.6 4.8e-05 23.3 0.4 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP83687.1 - 4.4e-05 24.0 0.1 7.7e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 GAP83687.1 - 0.074 12.6 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DUF633 PF04816.7 GAP83687.1 - 0.12 11.6 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF633) Diphthamide_syn PF01866.12 GAP83688.1 - 7.2e-112 373.5 0.0 8.4e-112 373.3 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DUF3328 PF11807.3 GAP83689.1 - 6.8e-28 97.8 1.2 8.9e-28 97.4 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) SKG6 PF08693.5 GAP83690.1 - 0.00035 19.8 0.0 0.00073 18.7 0.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM51 PF15345.1 GAP83690.1 - 0.051 13.2 0.1 0.07 12.8 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 HET PF06985.6 GAP83691.1 - 4.4e-19 69.0 2.6 1.3e-16 61.0 0.1 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HET PF06985.6 GAP83692.1 - 5.1e-20 72.0 0.7 1e-19 71.0 0.5 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1996 PF09362.5 GAP83693.1 - 1.5e-70 237.5 0.1 2e-70 237.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) AAA_16 PF13191.1 GAP83694.1 - 6e-08 32.8 0.7 2.4e-07 30.8 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 GAP83694.1 - 3.6e-07 29.9 0.1 1.8e-06 27.7 0.1 2.2 1 1 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 GAP83694.1 - 0.0001 22.0 0.0 0.00021 21.0 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 GAP83694.1 - 0.00062 19.9 0.1 0.0026 17.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 GAP83694.1 - 0.0022 16.8 0.0 0.0053 15.6 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.17 GAP83694.1 - 0.0033 17.5 0.0 0.0071 16.5 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA PF00004.24 GAP83694.1 - 0.0043 17.2 0.0 0.0093 16.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.20 GAP83694.1 - 0.0048 16.4 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ABC_tran PF00005.22 GAP83694.1 - 0.013 15.7 0.0 0.052 13.8 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_17 PF13207.1 GAP83694.1 - 0.018 15.8 0.0 0.07 13.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain Rad4 PF03835.10 GAP83694.1 - 0.021 14.2 0.1 1.3 8.3 0.0 2.3 1 1 1 2 2 2 0 Rad4 transglutaminase-like domain AAA_24 PF13479.1 GAP83694.1 - 0.027 14.0 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 GAP83694.1 - 0.031 13.6 0.0 0.081 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 GAP83694.1 - 0.032 13.9 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 GAP83694.1 - 0.043 13.7 0.0 0.11 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain TPR_1 PF00515.23 GAP83694.1 - 0.12 12.0 1.8 20 4.9 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 GAP83694.1 - 0.12 12.4 1.9 0.2 11.7 0.2 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 GAP83694.1 - 0.19 11.7 4.9 10 6.3 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAP83694.1 - 1.3 8.9 10.7 3.6 7.5 0.2 4.4 5 1 1 6 6 4 0 Tetratricopeptide repeat DUF2435 PF10363.4 GAP83695.1 - 1.8e-14 53.3 0.1 6.6e-14 51.5 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 GAP83695.1 - 2.3e-11 42.9 1.3 8.4e-11 41.1 0.9 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) DUF1977 PF09320.6 GAP83696.1 - 2.3e-21 76.0 0.0 3.7e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 GAP83696.1 - 3.8e-21 74.5 0.1 7.7e-21 73.6 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DUF3353 PF11833.3 GAP83697.1 - 0.024 14.0 0.3 0.026 14.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) DUF2611 PF11022.3 GAP83697.1 - 0.033 14.2 0.0 0.94 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2611) Y_phosphatase2 PF03162.8 GAP83698.1 - 8e-43 145.6 0.0 1.1e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 GAP83698.1 - 1.9e-07 31.4 0.0 4.6e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 GAP83698.1 - 0.00072 19.1 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAP83698.1 - 0.0033 16.7 0.0 0.0052 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DAO PF01266.19 GAP83699.1 - 4.1e-24 85.1 1.4 4e-23 81.8 1.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAP83699.1 - 0.0011 19.3 1.4 0.0024 18.2 0.3 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 GAP83699.1 - 0.0026 17.9 0.0 0.0067 16.6 0.0 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 GAP83699.1 - 0.0038 17.2 0.3 0.0082 16.1 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 GAP83699.1 - 0.0066 15.5 0.1 0.011 14.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 GAP83699.1 - 0.011 14.6 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 GAP83699.1 - 0.17 11.7 0.1 0.42 10.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 GAP83699.1 - 0.19 11.1 0.1 0.33 10.3 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Het-C PF07217.6 GAP83701.1 - 3.1e-284 943.8 0.0 3.9e-284 943.5 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Ydc2-catalyt PF09159.5 GAP83702.1 - 3.9e-61 206.9 0.0 4.8e-61 206.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.22 GAP83702.1 - 5.8e-09 35.2 0.0 2.7e-07 29.9 0.0 2.5 2 0 0 2 2 2 1 SAP domain Pox_A22 PF04848.8 GAP83702.1 - 0.022 14.6 0.0 2.7 7.8 0.0 2.7 3 0 0 3 3 3 0 Poxvirus A22 protein Pyr_redox_dim PF02852.17 GAP83703.1 - 7.4e-35 119.3 0.2 2.6e-33 114.3 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 GAP83703.1 - 1.1e-30 107.0 0.1 1.8e-30 106.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAP83703.1 - 3e-15 56.3 0.0 8.4e-15 54.9 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP83703.1 - 1.6e-06 28.3 0.0 4.1e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAP83703.1 - 0.041 12.7 0.0 0.78 8.5 0.0 2.1 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.13 GAP83703.1 - 0.18 11.4 1.0 0.42 10.2 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SOG2 PF10428.4 GAP83704.1 - 1.7e-91 307.1 0.0 1.7e-91 307.1 0.0 3.0 4 0 0 4 4 4 1 RAM signalling pathway protein LRR_4 PF12799.2 GAP83704.1 - 2.2e-15 55.8 10.8 9.1e-08 31.5 0.9 3.9 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAP83704.1 - 3.9e-13 48.9 10.2 5.8e-07 29.1 1.9 3.1 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 GAP83704.1 - 1.3e-08 33.6 12.1 0.31 11.2 0.0 6.6 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 GAP83704.1 - 3.3e-06 26.3 7.4 3.6 8.2 0.0 5.7 5 0 0 5 5 5 3 Leucine rich repeat LRR_6 PF13516.1 GAP83704.1 - 0.012 15.6 5.9 7.8 6.9 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich repeat Helicase_C PF00271.26 GAP83705.1 - 2.1e-20 72.3 0.0 2.6e-16 59.2 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 GAP83705.1 - 1.6e-15 56.9 0.0 3.8e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase GCN5L1 PF06320.8 GAP83706.1 - 1.4e-05 24.8 1.1 2.2e-05 24.2 0.8 1.2 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) DUF2968 PF11180.3 GAP83706.1 - 0.19 11.0 3.6 0.29 10.5 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Steroid_dh PF02544.11 GAP83707.1 - 9.5e-31 106.5 0.6 1.4e-30 106.0 0.4 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 GAP83707.1 - 1.2e-05 25.3 0.5 2.5e-05 24.3 0.4 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 GAP83707.1 - 0.00032 20.0 0.2 0.00052 19.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) zf-TRAF PF02176.13 GAP83708.1 - 6.6e-13 48.8 31.7 3.3e-06 27.3 1.9 3.9 2 1 2 4 4 3 3 TRAF-type zinc finger zf-RING_5 PF14634.1 GAP83708.1 - 1.9e-07 30.6 5.3 1.9e-07 30.6 3.6 3.7 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAP83708.1 - 9.9e-07 28.6 8.0 9.9e-07 28.6 5.6 3.8 2 1 2 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAP83708.1 - 1.2e-05 25.0 7.1 1.2e-05 25.0 5.0 3.6 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 GAP83708.1 - 2.4e-05 23.9 4.7 2.4e-05 23.9 3.2 3.8 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAP83708.1 - 7.7e-05 22.2 8.2 7.7e-05 22.2 5.7 4.2 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAP83708.1 - 8.6e-05 22.3 8.7 8.6e-05 22.3 6.0 2.7 4 0 0 4 4 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 GAP83708.1 - 0.0092 15.6 5.6 0.0092 15.6 3.9 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 GAP83708.1 - 0.01 15.6 1.3 0.01 15.6 0.9 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger TelA PF05816.6 GAP83708.1 - 0.13 10.8 0.0 0.28 9.8 0.0 1.5 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) Sina PF03145.11 GAP83708.1 - 0.87 9.2 16.9 0.15 11.6 0.8 2.7 1 1 2 3 3 2 0 Seven in absentia protein family IBR PF01485.16 GAP83708.1 - 1.4 8.8 26.9 4.7 7.1 0.9 4.3 2 1 1 3 3 3 0 IBR domain zf-RING_6 PF14835.1 GAP83708.1 - 4.2 7.2 12.0 0.16 11.7 2.4 2.7 2 1 0 2 2 2 0 zf-RING of BARD1-type protein zf-P11 PF03854.9 GAP83708.1 - 5.1 6.6 9.9 3.1 7.3 1.3 3.0 1 1 1 2 2 2 0 P-11 zinc finger DENN PF02141.16 GAP83709.1 - 9.6e-40 136.2 0.0 1.6e-39 135.5 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 GAP83709.1 - 9.6e-06 25.4 0.1 3.6e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 uDENN domain PCRF PF03462.13 GAP83709.1 - 0.11 12.2 3.9 1.5 8.5 0.3 2.4 2 0 0 2 2 2 0 PCRF domain DUF2570 PF10828.3 GAP83709.1 - 1 8.9 13.4 0.52 9.9 6.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) Pirin PF02678.11 GAP83713.1 - 3e-31 107.4 0.0 5.2e-31 106.6 0.0 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 GAP83713.1 - 8.5e-23 80.4 0.0 1.7e-21 76.2 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 GAP83713.1 - 2.8e-05 23.5 0.5 9.6e-05 21.8 0.3 1.9 2 0 0 2 2 2 1 Cupin domain Glyco_hydro_11 PF00457.12 GAP83715.1 - 9.7e-61 204.3 15.9 1.2e-60 204.0 11.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Ank PF00023.25 GAP83716.1 - 2.4e-45 150.1 16.9 6.4e-09 35.1 0.1 7.0 6 0 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.2 GAP83716.1 - 3e-44 149.2 9.6 1.7e-18 66.7 1.3 4.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAP83716.1 - 6.5e-43 144.3 13.2 2.3e-11 43.8 0.1 7.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP83716.1 - 5.2e-40 134.5 24.8 5.9e-12 45.4 0.6 5.3 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP83716.1 - 8.7e-34 112.1 4.9 3.1e-05 23.7 0.0 7.9 7 0 0 7 7 7 6 Ankyrin repeat NACHT PF05729.7 GAP83716.1 - 1.2e-08 34.8 0.0 2.8e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 GAP83716.1 - 2.1e-05 23.5 0.0 0.01 14.7 0.0 2.7 2 0 0 2 2 2 2 NB-ARC domain V-SNARE PF05008.10 GAP83716.1 - 0.00025 21.1 5.3 0.00039 20.5 0.3 3.3 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus AAA_16 PF13191.1 GAP83716.1 - 0.00065 19.7 3.8 0.013 15.5 0.0 3.6 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 GAP83716.1 - 0.0044 17.1 2.9 1.2 9.2 0.0 3.9 3 1 0 3 3 3 1 AAA domain Shigella_OspC PF06128.6 GAP83716.1 - 0.035 13.5 1.7 0.47 9.8 0.1 2.9 2 1 2 4 4 4 0 Shigella flexneri OspC protein Syntaxin_2 PF14523.1 GAP83716.1 - 0.07 13.1 11.3 0.14 12.1 0.6 3.5 3 0 0 3 3 3 0 Syntaxin-like protein Syntaxin PF00804.20 GAP83716.1 - 0.072 13.2 7.5 0.045 13.9 1.3 2.8 2 0 0 2 2 2 0 Syntaxin AAA_13 PF13166.1 GAP83716.1 - 0.11 10.9 4.6 0.18 10.2 3.2 1.2 1 0 0 1 1 1 0 AAA domain But2 PF09792.4 GAP83717.1 - 4.1e-05 23.3 0.0 0.29 10.8 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin 3 binding protein But2 C-terminal domain DUF3712 PF12505.3 GAP83718.1 - 2.4e-10 40.4 0.2 1.1e-06 28.6 0.0 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF3712) LEA_2 PF03168.8 GAP83718.1 - 0.00044 20.5 1.5 1.6 9.1 0.4 4.2 4 0 0 4 4 4 2 Late embryogenesis abundant protein OTCace PF00185.19 GAP83719.1 - 2.2e-39 134.8 0.0 3.5e-39 134.2 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 GAP83719.1 - 1.2e-38 131.9 0.0 1.7e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain ALS_ss_C PF10369.4 GAP83720.1 - 1e-17 63.6 0.0 1.4e-16 59.9 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 GAP83720.1 - 3.6e-12 45.4 0.1 6.5e-12 44.6 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 GAP83720.1 - 2.1e-09 37.0 0.0 3.6e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 ACT domain KH_1 PF00013.24 GAP83721.1 - 3.4e-12 45.8 0.0 1.2e-08 34.5 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 GAP83721.1 - 9.3e-08 31.5 0.8 1.8e-05 24.2 0.0 2.8 2 0 0 2 2 2 2 KH domain CDK2AP PF09806.4 GAP83721.1 - 0.41 10.8 5.6 2.1 8.5 0.6 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Ank_2 PF12796.2 GAP83722.1 - 2.9e-55 184.5 0.0 3.8e-19 68.8 0.1 6.9 3 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAP83722.1 - 3e-46 153.0 4.4 2e-07 30.4 0.0 10.9 11 0 0 11 11 11 7 Ankyrin repeat Ank_4 PF13637.1 GAP83722.1 - 3e-42 142.2 0.8 1.2e-10 41.6 0.0 8.9 5 2 4 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP83722.1 - 1.4e-38 130.0 2.7 4e-09 36.4 0.0 7.6 8 1 1 9 9 9 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP83722.1 - 1e-30 102.6 1.8 0.00051 20.0 0.0 10.8 11 0 0 11 11 11 6 Ankyrin repeat AAA_16 PF13191.1 GAP83722.1 - 1.4e-06 28.4 0.0 1e-05 25.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 GAP83722.1 - 4.9e-06 26.2 0.0 2.6e-05 23.9 0.0 2.2 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 GAP83722.1 - 0.00069 19.7 0.0 0.0019 18.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 GAP83722.1 - 0.012 15.2 0.0 0.038 13.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MCR_gamma PF02240.11 GAP83723.1 - 0.029 13.4 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase gamma subunit Peptidase_S8 PF00082.17 GAP83724.1 - 8.9e-13 48.0 0.0 2.4e-12 46.6 0.0 1.7 2 0 0 2 2 2 1 Subtilase family Ank_2 PF12796.2 GAP83724.1 - 1.4e-11 44.5 1.1 1.3e-05 25.4 0.3 3.2 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAP83724.1 - 9.5e-07 28.4 7.6 0.23 11.8 0.0 5.5 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.1 GAP83724.1 - 1.1e-06 28.6 2.5 0.018 15.3 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAP83724.1 - 1.4e-05 25.4 1.8 0.71 10.4 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 GAP83724.1 - 0.00096 18.8 4.6 0.013 15.2 0.0 4.5 5 1 0 5 5 5 1 Ankyrin repeat DUF974 PF06159.8 GAP83725.1 - 3.3e-79 265.8 0.0 4.2e-79 265.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Gryzun PF07919.7 GAP83725.1 - 4.1e-05 22.1 0.0 6.4e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi DENN PF02141.16 GAP83726.1 - 2e-53 180.8 0.0 3.4e-53 180.1 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 GAP83726.1 - 1.8e-17 63.0 0.0 3.7e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 GAP83726.1 - 2.3e-16 59.5 0.1 4.6e-16 58.6 0.1 1.5 1 0 0 1 1 1 1 dDENN domain C1_3 PF07649.7 GAP83726.1 - 0.2 11.7 6.1 0.34 10.9 4.2 1.4 1 0 0 1 1 1 0 C1-like domain PHD PF00628.24 GAP83726.1 - 1.5 8.5 8.7 2.7 7.7 6.0 1.4 1 0 0 1 1 1 0 PHD-finger MMR_HSR1 PF01926.18 GAP83727.1 - 1.9e-05 24.5 0.0 5.3e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GET2 PF08690.5 GAP83728.1 - 2.1e-08 33.8 4.2 1.1e-05 24.8 0.5 3.5 2 2 0 2 2 2 2 GET complex subunit GET2 bZIP_C PF12498.3 GAP83728.1 - 0.72 11.1 6.8 2.4 9.4 4.7 1.9 1 1 0 1 1 1 0 Basic leucine-zipper C terminal CDC45 PF02724.9 GAP83729.1 - 0.00097 17.2 0.8 0.00097 17.2 0.6 1.1 1 0 0 1 1 1 1 CDC45-like protein Daxx PF03344.10 GAP83729.1 - 0.025 13.0 8.4 0.033 12.6 5.8 1.2 1 0 0 1 1 1 0 Daxx Family DUF2201_N PF13203.1 GAP83729.1 - 0.1 11.7 0.5 0.15 11.2 0.4 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Mito_fiss_reg PF05308.6 GAP83729.1 - 0.14 11.5 5.6 0.18 11.1 3.9 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Sigma70_ner PF04546.8 GAP83729.1 - 0.63 9.6 8.4 0.96 9.0 5.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region PPP4R2 PF09184.6 GAP83729.1 - 1.1 8.7 12.7 1.5 8.2 8.8 1.1 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.7 GAP83729.1 - 1.2 8.3 10.7 1.6 7.9 7.4 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 GAP83729.1 - 3 5.6 13.9 3.8 5.3 9.6 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 GAP83729.1 - 3.3 6.3 18.7 4.7 5.8 13.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.7 GAP83729.1 - 5.2 6.7 10.7 7.1 6.2 7.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.7 GAP83729.1 - 9.5 5.3 12.1 14 4.8 8.4 1.2 1 0 0 1 1 1 0 NOA36 protein Glyco_hydro_18 PF00704.23 GAP83731.1 - 3.3e-20 72.8 1.1 3.3e-20 72.8 0.8 1.6 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 SART-1 PF03343.8 GAP83732.1 - 9.4e-153 509.7 55.4 1.1e-152 509.6 38.4 1.0 1 0 0 1 1 1 1 SART-1 family Glyco_hydro_15 PF00723.16 GAP83733.1 - 1.2e-104 350.4 0.1 1.6e-104 350.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 GAP83733.1 - 4.3e-33 112.7 1.4 1e-32 111.6 1.0 1.7 1 0 0 1 1 1 1 Starch binding domain Fructosamin_kin PF03881.9 GAP83735.1 - 3.8e-75 252.5 0.0 4.4e-75 252.3 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 GAP83735.1 - 0.00018 21.3 0.0 0.00027 20.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 GAP83735.1 - 0.051 12.2 0.0 0.081 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) ATP-grasp_2 PF08442.5 GAP83736.1 - 7.8e-78 260.4 0.3 7.8e-78 260.4 0.2 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 GAP83736.1 - 8.6e-27 93.6 0.5 1.7e-26 92.6 0.4 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 GAP83736.1 - 1.2e-09 37.7 0.0 2.7e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 GAP83736.1 - 0.00028 20.5 1.1 0.012 15.2 0.1 2.7 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 GAP83736.1 - 0.018 14.7 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain p450 PF00067.17 GAP83737.1 - 4.3e-55 187.0 0.0 6e-55 186.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HSF_DNA-bind PF00447.12 GAP83739.1 - 2.8e-36 123.8 0.7 5.3e-36 122.9 0.5 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Aa_trans PF01490.13 GAP83741.1 - 3.2e-55 187.2 34.7 3.6e-55 187.0 24.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein GMC_oxred_N PF00732.14 GAP83742.1 - 4.6e-32 111.3 0.0 1.9e-30 106.0 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAP83742.1 - 2.5e-30 105.6 0.0 4.7e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAP83742.1 - 1.3e-06 27.5 0.0 0.0061 15.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAP83742.1 - 3.5e-05 22.8 0.0 0.00012 21.1 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAP83742.1 - 3.9e-05 23.5 0.1 0.00012 22.0 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAP83742.1 - 0.00023 21.1 0.0 0.0013 18.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAP83742.1 - 0.0048 15.8 0.0 0.013 14.4 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 GAP83742.1 - 0.0056 15.5 0.1 0.2 10.4 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 GAP83742.1 - 0.024 15.0 0.0 0.077 13.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAP83742.1 - 0.026 13.6 0.1 0.043 12.8 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 GAP83742.1 - 0.045 13.8 0.0 3.5 7.6 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAP83742.1 - 0.047 12.1 0.0 0.074 11.5 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 GAP83742.1 - 0.093 11.8 0.1 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family SDA1 PF05285.7 GAP83743.1 - 9.7e-83 278.1 38.0 9.7e-83 278.1 26.3 2.5 3 0 0 3 3 3 2 SDA1 NUC130_3NT PF08158.7 GAP83743.1 - 2.2e-17 63.0 0.0 5.4e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 NUC130/3NT domain Plasmod_dom_1 PF09715.5 GAP83743.1 - 0.061 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Plasmodium protein of unknown function (Plasmod_dom_1) Pkinase PF00069.20 GAP83744.1 - 2.8e-53 180.7 0.0 3.8e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP83744.1 - 9.2e-40 136.3 0.0 1.3e-39 135.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP83744.1 - 0.00014 20.9 0.0 0.00033 19.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 GAP83744.1 - 0.0096 15.6 0.0 0.11 12.1 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 GAP83744.1 - 0.011 14.8 0.0 0.04 12.9 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2934 PF11154.3 GAP83744.1 - 0.06 12.7 0.2 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) His_Phos_1 PF00300.17 GAP83745.1 - 6.7e-21 75.0 0.1 2.2e-20 73.3 0.1 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DASH_Dad3 PF08656.5 GAP83746.1 - 7.9e-29 99.1 0.1 8.7e-29 99.0 0.1 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 Ribosomal_S5_C PF03719.10 GAP83747.1 - 1.9e-18 65.5 0.0 5.5e-18 64.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 GAP83747.1 - 8.3e-09 35.0 0.1 1.5e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DUF4366 PF14283.1 GAP83748.1 - 0.014 14.8 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) S1FA PF04689.8 GAP83748.1 - 0.031 14.1 0.2 0.036 13.9 0.1 1.1 1 0 0 1 1 1 0 DNA binding protein S1FA OAD_gamma PF04277.8 GAP83748.1 - 0.034 14.4 0.1 0.049 13.9 0.1 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain ATP_synt_I PF03899.10 GAP83748.1 - 0.051 13.7 0.0 0.063 13.4 0.0 1.1 1 0 0 1 1 1 0 ATP synthase I chain Ni_hydr_CYTB PF01292.15 GAP83748.1 - 0.072 12.4 0.0 0.073 12.4 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 2TM PF13239.1 GAP83748.1 - 0.1 12.6 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 2TM domain Vpu PF00558.14 GAP83748.1 - 0.13 11.8 0.1 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Vpu protein Ecm29 PF13001.2 GAP83749.1 - 0.03 12.8 0.4 0.043 12.3 0.3 1.1 1 0 0 1 1 1 0 Proteasome stabiliser Ribosomal_L16 PF00252.13 GAP83750.1 - 7e-29 100.2 0.5 8.4e-29 100.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RFC1 PF08519.7 GAP83751.1 - 1.5e-55 187.2 0.0 3.4e-55 186.0 0.0 1.7 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 GAP83751.1 - 1e-14 54.4 0.0 2.2e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 GAP83751.1 - 2.5e-09 37.4 0.0 8e-09 35.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 GAP83751.1 - 1.2e-05 24.2 0.0 2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 GAP83751.1 - 5.2e-05 23.3 0.0 0.0002 21.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAP83751.1 - 0.00027 20.6 0.1 0.00085 19.0 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 GAP83751.1 - 0.00057 20.6 0.0 0.00057 20.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 GAP83751.1 - 0.0015 18.5 0.0 0.056 13.4 0.0 2.9 1 1 1 2 2 2 1 AAA ATPase domain DNA_pol3_delta PF06144.8 GAP83751.1 - 0.0016 17.9 0.0 0.0053 16.2 0.0 1.9 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_18 PF13238.1 GAP83751.1 - 0.0066 16.7 0.1 0.0066 16.7 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 GAP83751.1 - 0.016 15.1 0.0 0.049 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 GAP83751.1 - 0.018 15.0 0.9 0.097 12.6 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.1 GAP83751.1 - 0.018 14.9 0.0 0.051 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 GAP83751.1 - 0.019 14.6 0.1 2 8.0 0.0 2.7 3 0 0 3 3 3 0 NACHT domain RuvB_N PF05496.7 GAP83751.1 - 0.043 12.8 0.0 0.079 11.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DEAD PF00270.24 GAP83751.1 - 0.054 12.9 0.1 3.3 7.1 0.0 2.5 1 1 1 2 2 2 0 DEAD/DEAH box helicase PTCB-BRCT PF12738.2 GAP83751.1 - 0.074 12.9 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 twin BRCT domain AAA_5 PF07728.9 GAP83751.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ERF PF04404.7 GAP83752.1 - 0.31 10.5 1.1 0.66 9.4 0.8 1.4 1 0 0 1 1 1 0 ERF superfamily GrpE PF01025.14 GAP83753.1 - 5.2e-50 169.2 6.2 6.7e-50 168.8 4.3 1.1 1 0 0 1 1 1 1 GrpE DUF334 PF03904.8 GAP83753.1 - 0.057 12.7 1.4 0.079 12.2 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) RNA_pol_A_bac PF01000.21 GAP83754.1 - 1.2e-31 109.1 0.0 1.8e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 GAP83754.1 - 4.1e-15 54.6 0.0 5.3e-15 54.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Mito_carr PF00153.22 GAP83755.1 - 1e-52 175.7 0.5 6.3e-20 70.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CNTF PF01110.12 GAP83755.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Ciliary neurotrophic factor tRNA-synt_2d PF01409.15 GAP83756.1 - 1.7e-47 161.6 0.0 9.7e-25 87.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 GAP83756.1 - 1.4e-24 86.0 0.0 3e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.15 GAP83756.1 - 0.11 11.2 0.1 0.33 9.6 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) Calcipressin PF04847.7 GAP83757.1 - 1.6e-50 171.2 0.2 1.9e-50 170.9 0.1 1.1 1 0 0 1 1 1 1 Calcipressin Phage_cap_P2 PF05125.7 GAP83757.1 - 0.097 11.5 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Phage major capsid protein, P2 family DUF2236 PF09995.4 GAP83758.1 - 2.3e-33 115.4 3.2 3.4e-33 114.9 2.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Neugrin PF06413.6 GAP83759.1 - 5.8e-14 52.4 0.2 1e-13 51.6 0.2 1.3 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.2 GAP83759.1 - 2.8e-06 27.4 0.4 5.6e-06 26.4 0.3 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_29 PF13551.1 GAP83759.1 - 0.0012 19.0 0.2 0.019 15.1 0.0 2.5 2 0 0 2 2 2 1 Winged helix-turn helix DUF383 PF04063.9 GAP83759.1 - 0.04 13.4 0.0 0.079 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF383) ADH_zinc_N PF00107.21 GAP83760.1 - 4e-08 32.8 0.0 8.8e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP83760.1 - 5.1e-05 23.0 0.4 0.00012 21.7 0.2 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.17 GAP83762.1 - 4e-29 101.4 0.0 4.9e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2195 PF09961.4 GAP83762.1 - 0.04 13.7 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2195) FliX PF10768.4 GAP83762.1 - 0.073 13.2 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Class II flagellar assembly regulator MFS_1 PF07690.11 GAP83763.1 - 1e-34 119.8 51.2 4e-34 117.8 35.5 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAP83763.1 - 1.5e-17 63.0 21.6 2.2e-17 62.5 15.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAP83763.1 - 9.4e-11 40.9 27.4 1.1e-10 40.7 8.8 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter zf-LITAF-like PF10601.4 GAP83763.1 - 1.4 8.8 6.0 18 5.3 0.0 4.3 4 1 1 5 5 5 0 LITAF-like zinc ribbon domain Zn_clus PF00172.13 GAP83765.1 - 1.6e-06 27.9 9.8 3.6e-06 26.7 6.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.23 GAP83766.1 - 2e-76 257.0 0.0 3.4e-76 256.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 GAP83766.1 - 4.9e-72 242.4 0.0 1.6e-71 240.7 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAP83766.1 - 4.7e-58 197.0 0.1 1e-57 195.9 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Condensation PF00668.15 GAP83766.1 - 1.8e-48 164.9 0.2 3.4e-48 164.0 0.2 1.4 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.1 GAP83766.1 - 1e-47 162.7 0.3 1.9e-47 161.8 0.2 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 GAP83766.1 - 3.5e-47 160.4 0.2 1.4e-46 158.4 0.0 2.2 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 GAP83766.1 - 1.1e-37 129.5 1.1 5.6e-37 127.2 0.0 2.6 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 GAP83766.1 - 1.1e-36 126.0 0.0 3.4e-35 121.1 0.0 2.6 2 0 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.17 GAP83766.1 - 2.3e-29 101.6 0.0 7.4e-29 100.0 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 GAP83766.1 - 2.4e-18 66.1 1.8 2.7e-09 37.1 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 GAP83766.1 - 1.1e-15 57.9 0.0 5.2e-15 55.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain HxxPF_rpt PF13745.1 GAP83766.1 - 4.3e-14 52.5 0.0 1.5e-13 50.8 0.0 2.0 1 0 0 1 1 1 1 HxxPF-repeated domain Epimerase PF01370.16 GAP83766.1 - 1.1e-11 44.6 0.0 9.1e-10 38.3 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.1 GAP83766.1 - 9.5e-11 41.6 0.0 2.7e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP83766.1 - 9e-10 38.3 0.0 3.2e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP83766.1 - 1.7e-09 38.0 0.0 5.4e-09 36.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP83766.1 - 2.7e-07 31.1 0.1 1.7e-06 28.5 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 GAP83766.1 - 0.0002 20.1 0.0 0.0004 19.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.13 GAP83766.1 - 0.00041 19.5 0.0 0.00087 18.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 GAP83766.1 - 0.0013 18.2 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Thiolase_N PF00108.18 GAP83766.1 - 0.0027 16.7 0.0 0.0049 15.8 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain RrnaAD PF00398.15 GAP83766.1 - 0.012 14.6 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase WD40 PF00400.27 GAP83767.1 - 1.6e-12 46.7 13.5 0.00099 18.9 0.1 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat PQQ_2 PF13360.1 GAP83767.1 - 0.0032 16.9 0.0 0.05 13.0 0.0 3.0 2 2 1 3 3 3 1 PQQ-like domain Phage_CI_repr PF07022.8 GAP83767.1 - 0.1 12.7 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Rgp1 PF08737.5 GAP83768.1 - 6.9e-120 400.9 0.0 2.9e-119 398.8 0.0 1.8 2 0 0 2 2 2 1 Rgp1 Arrestin_C PF02752.17 GAP83768.1 - 0.0066 16.5 0.1 0.15 12.1 0.0 2.9 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 GAP83768.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain COesterase PF00135.23 GAP83769.1 - 2.9e-79 267.2 0.7 5.8e-79 266.2 0.5 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAP83769.1 - 1.8e-06 27.7 0.0 3.7e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP83769.1 - 0.0074 16.0 0.1 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAP83769.1 - 0.02 14.1 0.1 0.043 13.0 0.0 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family Ribonuclease_3 PF00636.21 GAP83771.1 - 3.8e-42 143.3 0.0 3.9e-22 78.8 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 GAP83771.1 - 8.5e-25 87.1 0.0 3.1e-14 53.0 0.0 3.7 3 0 0 3 3 3 3 Ribonuclease-III-like DEAD PF00270.24 GAP83771.1 - 2.1e-19 69.6 0.0 5.4e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP83771.1 - 9.7e-19 67.0 0.0 3.2e-18 65.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 GAP83771.1 - 4.1e-13 48.9 0.0 9.1e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain ResIII PF04851.10 GAP83771.1 - 3.9e-10 39.8 0.0 8.9e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 GAP83771.1 - 0.01 14.6 0.0 0.019 13.7 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain DEAD_2 PF06733.10 GAP83771.1 - 0.022 14.1 0.0 0.053 12.9 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 Proteasome PF00227.21 GAP83772.1 - 5.1e-52 175.9 0.0 2.1e-28 98.8 0.0 2.0 2 0 0 2 2 2 2 Proteasome subunit RINGv PF12906.2 GAP83773.1 - 4.1e-11 42.7 1.1 4.1e-11 42.7 0.8 2.1 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 GAP83773.1 - 0.06 13.1 2.4 0.12 12.2 0.4 2.1 2 0 0 2 2 2 0 Ring finger domain PHD PF00628.24 GAP83773.1 - 1.1 8.9 4.7 0.48 10.1 1.4 1.7 2 0 0 2 2 2 0 PHD-finger Glyco_transf_34 PF05637.7 GAP83774.1 - 2.7e-71 239.8 0.0 3.4e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 GAP83774.1 - 9.8e-05 21.7 0.0 0.12 11.7 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function, DUF273 Pyridoxal_deC PF00282.14 GAP83775.1 - 4.3e-18 64.9 0.0 6.1e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 GAP83775.1 - 0.005 15.6 0.0 0.0089 14.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 GAP83775.1 - 0.014 14.4 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family BCDHK_Adom3 PF10436.4 GAP83777.1 - 5e-69 231.0 0.0 6.9e-69 230.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 GAP83777.1 - 7.6e-13 48.1 0.0 2.1e-12 46.7 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 GAP83777.1 - 0.054 13.1 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Packaging_FI PF14000.1 GAP83778.1 - 0.0025 17.9 0.9 0.43 10.7 0.0 2.4 2 0 0 2 2 2 1 DNA packaging protein FI CENP-F_leu_zip PF10473.4 GAP83778.1 - 0.22 11.3 11.1 0.11 12.3 5.2 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 GAP83778.1 - 1.1 8.2 8.4 1.6 7.7 5.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 FlaC_arch PF05377.6 GAP83778.1 - 2.5 8.0 4.3 4.1 7.3 0.1 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) FUSC PF04632.7 GAP83778.1 - 6.7 5.0 5.0 5.2 5.3 1.9 1.7 2 0 0 2 2 2 0 Fusaric acid resistance protein family WLM PF08325.5 GAP83779.1 - 9.3e-28 97.3 0.0 2.6e-27 95.8 0.0 1.7 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.12 GAP83779.1 - 0.00072 19.3 1.8 0.0012 18.6 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.4 GAP83779.1 - 0.0028 17.3 0.0 0.0039 16.8 0.0 1.2 1 0 0 1 1 1 1 SprT-like family Peptidase_MA_2 PF13485.1 GAP83779.1 - 0.073 13.1 0.5 0.15 12.1 0.3 1.4 1 1 0 1 1 1 0 Peptidase MA superfamily ubiquitin PF00240.18 GAP83779.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family DUF955 PF06114.8 GAP83779.1 - 0.15 11.8 0.2 0.24 11.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF955) ER_lumen_recept PF00810.13 GAP83780.1 - 7.1e-54 182.3 5.9 1.1e-53 181.7 4.1 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 GAP83780.1 - 1.4 8.5 0.0 1.4 8.5 0.0 3.7 4 1 0 4 4 4 0 PQ loop repeat Adeno_E3_CR2 PF02439.10 GAP83781.1 - 0.12 11.9 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 IMS_HHH PF11798.3 GAP83781.1 - 0.16 12.0 0.1 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 IMS family HHH motif Rifin_STEVOR PF02009.11 GAP83781.1 - 0.56 9.7 4.2 1.8 8.1 2.9 1.7 1 1 0 1 1 1 0 Rifin/stevor family Ctf8 PF09696.5 GAP83782.1 - 1.7e-32 111.7 0.0 2.3e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Ctf8 Ribosomal_S6e PF01092.14 GAP83783.1 - 5.3e-62 207.1 0.3 1.1e-61 206.0 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Pribosyltran_N PF13793.1 GAP83784.1 - 1e-42 144.5 0.5 3e-41 139.7 0.0 2.7 3 1 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 GAP83784.1 - 1.2e-37 129.4 3.6 7.8e-33 113.7 1.3 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 GAP83784.1 - 1.2e-14 54.1 1.0 3.6e-14 52.5 0.4 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 GAP83784.1 - 0.0007 18.8 0.1 0.0012 18.1 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF218 PF02698.12 GAP83784.1 - 0.037 13.5 0.0 0.12 11.8 0.0 1.8 1 1 0 1 1 1 0 DUF218 domain TFIID_30kDa PF03540.8 GAP83785.1 - 8.6e-24 83.1 0.4 1.3e-23 82.5 0.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.1 GAP83785.1 - 0.0092 16.4 0.2 0.0092 16.4 0.1 1.6 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 Cellulase PF00150.13 GAP83786.1 - 5.4e-55 186.5 7.0 6.4e-55 186.3 4.9 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF913 PF06025.7 GAP83787.1 - 1.4e-100 336.7 0.0 1.4e-100 336.7 0.0 2.7 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) HECT PF00632.20 GAP83787.1 - 2.8e-96 322.4 0.1 4.7e-96 321.6 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 GAP83787.1 - 5.2e-88 295.5 0.5 5.2e-88 295.5 0.3 3.0 2 1 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 GAP83787.1 - 4.9e-29 100.4 8.3 4.9e-29 100.4 5.8 4.7 3 2 1 4 4 4 1 Domain of unknown function (DUF4414) WW PF00397.21 GAP83788.1 - 1e-08 34.8 0.4 2.1e-08 33.8 0.3 1.6 1 0 0 1 1 1 1 WW domain DUF605 PF04652.11 GAP83788.1 - 0.0078 15.6 13.4 0.0085 15.5 9.1 1.3 1 1 0 1 1 1 1 Vta1 like Tubulin PF00091.20 GAP83789.1 - 5e-71 238.9 0.0 6.6e-71 238.5 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 GAP83789.1 - 3.3e-47 159.6 0.0 6e-47 158.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 GAP83789.1 - 0.0018 17.7 0.0 0.0048 16.3 0.0 1.7 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 GAP83789.1 - 0.14 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain EF-hand_4 PF12763.2 GAP83790.1 - 1.9e-34 117.5 0.0 4.3e-13 48.8 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.26 GAP83790.1 - 1.9e-06 27.4 0.1 4.1e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_7 PF13499.1 GAP83790.1 - 2.5e-06 27.5 0.0 0.00075 19.5 0.0 3.6 2 1 1 3 3 3 1 EF-hand domain pair COG2 PF06148.6 GAP83790.1 - 0.00081 19.2 14.7 0.013 15.3 2.2 2.5 1 1 1 2 2 2 2 COG (conserved oligomeric Golgi) complex component, COG2 TPR_MLP1_2 PF07926.7 GAP83790.1 - 0.00091 18.9 31.6 0.018 14.7 13.2 2.8 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein EF-hand_1 PF00036.27 GAP83790.1 - 0.0027 16.9 1.2 13 5.4 0.0 4.3 5 0 0 5 5 3 0 EF hand AAA_13 PF13166.1 GAP83790.1 - 0.0033 15.9 15.2 0.0054 15.2 10.5 1.2 1 0 0 1 1 1 1 AAA domain CENP-F_leu_zip PF10473.4 GAP83790.1 - 0.0038 17.0 26.3 0.013 15.3 6.2 2.5 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 GAP83790.1 - 0.005 16.4 33.1 0.27 10.8 15.1 2.4 1 1 1 2 2 2 2 IncA protein DUF3584 PF12128.3 GAP83790.1 - 0.0051 14.2 27.8 0.007 13.7 19.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF1664 PF07889.7 GAP83790.1 - 0.0051 16.6 4.3 0.0051 16.6 3.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) DUF812 PF05667.6 GAP83790.1 - 0.024 13.1 22.7 0.031 12.7 15.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Mnd1 PF03962.10 GAP83790.1 - 0.063 12.9 26.3 0.33 10.6 5.2 2.2 1 1 1 2 2 2 0 Mnd1 family EF-hand_6 PF13405.1 GAP83790.1 - 0.063 13.1 3.1 1.5 8.9 0.0 4.2 5 1 1 6 6 2 0 EF-hand domain TMF_TATA_bd PF12325.3 GAP83790.1 - 0.068 12.9 22.8 0.23 11.2 3.4 3.1 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding ATG16 PF08614.6 GAP83790.1 - 0.08 12.7 31.2 0.56 10.0 7.4 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Spc7 PF08317.6 GAP83790.1 - 0.11 11.0 28.1 0.061 11.9 7.4 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein AAA_27 PF13514.1 GAP83790.1 - 0.13 9.9 17.8 0.21 9.2 12.3 1.2 1 0 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 GAP83790.1 - 0.16 11.1 10.5 0.49 9.5 2.2 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Nit_Regul_Hom PF10126.4 GAP83790.1 - 0.29 10.9 0.0 0.83 9.4 0.0 1.7 2 0 0 2 2 1 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII WEMBL PF05701.6 GAP83790.1 - 0.31 9.4 21.5 0.46 8.8 14.9 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Myosin_tail_1 PF01576.14 GAP83790.1 - 0.34 8.5 29.5 0.66 7.6 20.4 1.3 1 1 0 1 1 1 0 Myosin tail Lebercilin PF15619.1 GAP83790.1 - 0.54 9.6 29.3 2.1 7.7 19.6 1.9 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease ADIP PF11559.3 GAP83790.1 - 0.67 9.8 32.0 2.6 7.9 7.0 2.6 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4201 PF13870.1 GAP83790.1 - 0.87 8.9 24.5 5 6.5 9.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Vac_Fusion PF02346.11 GAP83790.1 - 0.94 8.9 2.3 5 6.6 0.6 2.7 2 1 1 3 3 3 0 Chordopoxvirus fusion protein Rab5-bind PF09311.6 GAP83790.1 - 1.1 9.1 32.6 2.9 7.7 6.7 3.4 1 1 1 2 2 2 0 Rabaptin-like protein EzrA PF06160.7 GAP83790.1 - 1.8 6.6 20.8 5.1 5.1 14.5 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA APG6 PF04111.7 GAP83790.1 - 2.6 7.0 28.4 1.8 7.5 10.8 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 MscS_porin PF12795.2 GAP83790.1 - 2.8 7.1 38.9 0.4 9.9 11.3 2.4 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain TMCO5 PF14992.1 GAP83790.1 - 3.2 6.8 23.3 0.98 8.4 4.3 2.4 1 1 1 2 2 2 0 TMCO5 family CENP-Q PF13094.1 GAP83790.1 - 3.9 7.4 30.1 0.086 12.8 7.1 2.8 1 1 1 2 2 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4559 PF15112.1 GAP83790.1 - 4.1 6.4 12.3 7.2 5.6 8.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) FliJ PF02050.11 GAP83790.1 - 4.4 7.3 30.3 1.7 8.7 7.8 2.5 1 1 1 2 2 2 0 Flagellar FliJ protein DUF3450 PF11932.3 GAP83790.1 - 4.5 6.4 28.3 4.7 6.4 8.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) GAS PF13851.1 GAP83790.1 - 4.7 6.3 28.8 16 4.5 12.3 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.2 GAP83790.1 - 5.2 6.9 29.3 1.5 8.6 11.6 2.4 1 1 1 2 2 2 0 Tropomyosin like MAD PF05557.8 GAP83790.1 - 5.9 4.8 25.4 14 3.5 17.6 1.5 1 1 0 1 1 1 0 Mitotic checkpoint protein DUF724 PF05266.9 GAP83790.1 - 6 6.4 20.0 5 6.6 6.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) ERM PF00769.14 GAP83790.1 - 7.8 5.9 25.9 73 2.7 18.0 2.3 1 1 0 1 1 1 0 Ezrin/radixin/moesin family PHO4 PF01384.15 GAP83791.1 - 4.4e-87 291.7 11.2 5.7e-87 291.4 7.8 1.1 1 0 0 1 1 1 1 Phosphate transporter family Ribosomal_S8e PF01201.17 GAP83792.1 - 1.3e-47 161.2 1.4 1.5e-47 161.0 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.1 GAP83792.1 - 0.048 13.9 2.9 0.14 12.3 2.0 1.9 1 1 0 1 1 1 0 Small acidic protein family RabGAP-TBC PF00566.13 GAP83793.1 - 3.5e-47 160.6 0.0 5.5e-46 156.7 0.0 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Microtub_assoc PF07989.6 GAP83793.1 - 5.5e-05 22.9 19.6 0.0051 16.6 4.9 3.1 1 1 1 2 2 2 2 Microtubule associated PilJ PF13675.1 GAP83793.1 - 1.3 9.3 8.4 5 7.4 1.6 3.0 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term ADIP PF11559.3 GAP83793.1 - 4.1 7.2 34.3 0.25 11.2 5.5 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Cellulase PF00150.13 GAP83795.1 - 5.2e-52 176.7 2.5 6.6e-52 176.4 1.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Steroid_dh PF02544.11 GAP83796.1 - 5.6e-22 78.1 1.4 3e-21 75.7 0.9 2.1 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 GAP83796.1 - 4.2e-06 26.2 1.3 4.2e-06 26.2 0.9 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) PhyH PF05721.8 GAP83797.1 - 5.1e-13 49.5 0.1 7.5e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans_2 PF11951.3 GAP83797.1 - 8.6e-07 27.8 0.0 1.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP83797.1 - 7.5e-06 25.7 9.4 1.6e-05 24.6 6.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF544 PF04424.8 GAP83798.1 - 9.5e-16 57.6 0.0 1.5e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) DUF2370 PF10176.4 GAP83798.1 - 0.35 10.1 2.7 0.97 8.7 1.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) TRF PF08558.5 GAP83799.1 - 6.9e-42 143.4 0.5 1.4e-41 142.4 0.4 1.4 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 GAP83799.1 - 0.00011 22.1 0.0 0.00028 20.8 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAP83799.1 - 0.022 14.8 0.0 0.066 13.3 0.0 1.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain Aldedh PF00171.17 GAP83800.1 - 5.8e-186 618.3 0.7 6.5e-186 618.1 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAP83800.1 - 0.0019 16.9 0.0 0.0032 16.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) FAA_hydrolase PF01557.13 GAP83801.1 - 3.1e-53 180.4 0.0 3.8e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAD_binding_3 PF01494.14 GAP83802.1 - 1e-38 133.3 0.0 3.7e-23 82.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 GAP83802.1 - 8.6e-05 21.7 0.1 0.00014 21.0 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 GAP83802.1 - 0.00027 21.0 0.0 0.00046 20.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAP83802.1 - 0.00095 18.1 0.1 0.0014 17.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 GAP83802.1 - 0.0011 18.9 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAP83802.1 - 0.0018 16.8 0.0 0.0026 16.2 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 GAP83802.1 - 0.0027 17.6 0.0 0.0069 16.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAP83802.1 - 0.0056 15.6 0.0 0.012 14.4 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAP83802.1 - 0.0057 15.6 0.0 0.046 12.6 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein K_oxygenase PF13434.1 GAP83802.1 - 0.056 12.3 0.0 0.096 11.5 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 GAP83802.1 - 0.11 12.9 0.2 0.32 11.4 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAP83802.1 - 0.22 10.3 0.0 0.32 9.8 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Glyoxalase PF00903.20 GAP83803.1 - 2.5e-09 37.1 3.0 1e-08 35.1 1.1 2.4 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAP83803.1 - 0.00017 22.1 1.1 0.65 10.6 0.1 2.8 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 GAP83803.1 - 0.035 14.1 0.1 0.74 9.8 0.0 2.5 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Fungal_trans PF04082.13 GAP83804.1 - 1e-11 44.2 0.3 1.8e-11 43.4 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP83804.1 - 5.7e-09 35.7 12.3 9.8e-09 34.9 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TMEM89 PF15098.1 GAP83804.1 - 0.12 12.3 0.1 12 5.9 0.0 2.6 2 0 0 2 2 2 0 TMEM89 protein family Glycos_transf_1 PF00534.15 GAP83805.1 - 4.4e-30 104.3 0.0 1.7e-28 99.1 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 GAP83805.1 - 3.6e-10 40.2 2.9 1.2e-09 38.5 1.2 2.1 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 GAP83805.1 - 5.5e-09 36.2 0.0 1.8e-07 31.3 0.0 2.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 GAP83805.1 - 5.2e-07 29.5 0.1 4.9e-06 26.3 0.1 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 GAP83805.1 - 0.022 15.0 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 IPK PF03770.11 GAP83806.1 - 1.1e-54 185.1 0.0 3.5e-54 183.4 0.0 1.8 2 0 0 2 2 2 1 Inositol polyphosphate kinase Pam17 PF08566.5 GAP83806.1 - 0.016 14.8 0.1 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Tcp11 PF05794.8 GAP83807.1 - 3.8e-45 154.4 0.0 1.1e-44 152.9 0.0 1.7 2 0 0 2 2 2 1 T-complex protein 11 SPX PF03105.14 GAP83807.1 - 0.13 11.9 7.4 0.019 14.7 1.8 1.9 2 0 0 2 2 2 0 SPX domain T2SF PF00482.18 GAP83807.1 - 6.8 6.6 9.0 18 5.2 4.1 2.9 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F Mre11_DNA_bind PF04152.9 GAP83808.1 - 1.3e-52 178.1 1.7 1.3e-52 178.1 1.2 2.2 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 GAP83808.1 - 1e-24 87.0 2.6 1.6e-24 86.4 1.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAP83808.1 - 1.2e-06 28.4 0.1 2.8e-06 27.2 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain LicD PF04991.8 GAP83809.1 - 1.4e-35 123.3 4.4 2.5e-17 63.6 0.7 3.1 2 1 0 2 2 2 2 LicD family ADH_N PF08240.7 GAP83810.1 - 2.3e-08 33.7 0.0 6.2e-08 32.3 0.0 1.8 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Cpn10 PF00166.16 GAP83810.1 - 0.015 15.2 0.1 0.039 13.8 0.0 1.8 2 1 0 2 2 2 0 Chaperonin 10 Kd subunit Fungal_trans PF04082.13 GAP83811.1 - 3.7e-17 62.0 1.8 6.1e-17 61.3 0.3 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 GAP83811.1 - 3.2e-07 30.3 16.4 2.4e-05 24.4 2.6 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAP83811.1 - 3.6e-06 26.9 8.4 5.8e-05 23.1 0.9 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAP83811.1 - 5.6e-06 26.3 14.3 0.00042 20.4 3.2 3.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 GAP83811.1 - 0.00097 18.7 3.0 0.0027 17.3 2.1 1.8 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 GAP83811.1 - 0.034 14.2 1.2 0.055 13.6 0.1 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 GAP83811.1 - 0.056 13.5 4.5 1.9 8.6 3.3 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-UBR PF02207.15 GAP83811.1 - 1.4 8.6 8.4 0.16 11.7 0.4 2.5 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) zf-C2H2_4 PF13894.1 GAP83812.1 - 0.0054 16.9 1.4 2.4 8.6 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger CTD_bind PF04818.8 GAP83812.1 - 0.067 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase II-binding domain. zf-C2H2 PF00096.21 GAP83812.1 - 0.32 11.4 1.2 4.6 7.7 0.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF2583 PF10762.4 GAP83813.1 - 0.59 10.3 3.8 21 5.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) Cu_bind_like PF02298.12 GAP83814.1 - 0.005 16.5 0.1 0.016 14.9 0.0 1.8 1 1 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.15 GAP83814.1 - 0.021 15.0 1.9 0.12 12.6 0.4 2.2 1 1 1 2 2 2 0 Copper binding proteins, plastocyanin/azurin family RRM_1 PF00076.17 GAP83815.1 - 1.4e-14 53.4 0.1 2.6e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP83815.1 - 1.3e-11 44.3 0.0 2.3e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP83815.1 - 8.1e-10 38.4 0.2 1.5e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAP83815.1 - 0.024 14.4 0.1 0.046 13.4 0.1 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Ebola_NP PF05505.7 GAP83815.1 - 7.1 4.5 14.2 5.6 4.9 0.3 2.0 2 0 0 2 2 2 0 Ebola nucleoprotein Glycophorin_A PF01102.13 GAP83816.1 - 0.0058 16.3 0.8 0.0095 15.6 0.1 1.6 1 1 1 2 2 2 1 Glycophorin A DUF3147 PF11345.3 GAP83816.1 - 0.011 15.7 0.0 0.58 10.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3147) Podoplanin PF05808.6 GAP83816.1 - 0.016 14.8 5.3 0.013 15.0 2.6 1.5 1 1 0 1 1 1 0 Podoplanin GRAB PF10375.4 GAP83817.1 - 2.4e-08 33.2 0.1 4.5e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Myosin_tail_1 PF01576.14 GAP83817.1 - 6e-07 27.6 52.0 8.5e-07 27.1 36.0 1.2 1 0 0 1 1 1 1 Myosin tail WEMBL PF05701.6 GAP83817.1 - 1.4e-05 23.7 51.7 0.0052 15.3 11.6 3.1 1 1 2 3 3 3 3 Weak chloroplast movement under blue light CENP-F_leu_zip PF10473.4 GAP83817.1 - 0.00021 21.1 60.1 0.14 11.9 12.0 3.3 1 1 1 3 3 3 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.7 GAP83817.1 - 0.0021 18.2 17.3 0.045 13.9 0.3 4.3 3 2 1 4 4 4 2 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 GAP83817.1 - 0.0041 16.3 14.9 0.071 12.2 0.4 3.1 1 1 2 3 3 3 2 Reovirus sigma C capsid protein Filament PF00038.16 GAP83817.1 - 0.0077 15.7 51.6 0.43 10.0 11.2 2.8 1 1 1 2 2 2 2 Intermediate filament protein Baculo_PEP_C PF04513.7 GAP83817.1 - 0.017 14.9 14.4 0.76 9.6 5.1 3.0 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_27 PF13514.1 GAP83817.1 - 0.075 10.7 48.0 0.11 10.2 33.2 1.1 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.5 GAP83817.1 - 0.098 12.7 25.5 0.036 14.1 5.3 4.2 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family IncA PF04156.9 GAP83817.1 - 0.13 11.8 59.6 0.2 11.2 7.4 3.3 1 1 1 2 2 1 0 IncA protein TPR_MLP1_2 PF07926.7 GAP83817.1 - 0.39 10.4 55.7 0.21 11.3 9.7 3.8 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 GAP83817.1 - 0.4 9.6 50.7 0.019 14.0 17.3 2.8 1 1 2 3 3 3 0 Autophagy protein Apg6 COG5 PF10392.4 GAP83817.1 - 0.4 10.6 20.3 1.4 8.8 4.0 3.6 1 1 1 3 3 3 0 Golgi transport complex subunit 5 Lectin_N PF03954.9 GAP83817.1 - 0.78 9.1 19.8 1.1 8.6 0.3 3.4 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain DUF3450 PF11932.3 GAP83817.1 - 1.3 8.2 43.8 0.62 9.2 6.5 3.9 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF1664 PF07889.7 GAP83817.1 - 1.4 8.6 23.8 2.4 7.9 4.9 3.9 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) DUF3584 PF12128.3 GAP83817.1 - 3.4 4.8 52.0 12 3.1 35.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) IFT57 PF10498.4 GAP83817.1 - 5 5.7 33.2 0.93 8.1 14.0 2.3 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Tropomyosin PF00261.15 GAP83817.1 - 5.2 6.0 60.8 4.6 6.2 19.4 3.2 1 1 0 2 2 2 0 Tropomyosin DivIVA PF05103.8 GAP83817.1 - 5.4 7.0 49.9 1.2 9.2 8.0 3.8 1 1 2 3 3 3 0 DivIVA protein HOOK PF05622.7 GAP83817.1 - 6.4 4.4 51.1 0.15 9.8 22.5 2.1 1 1 1 2 2 2 0 HOOK protein V_ATPase_I PF01496.14 GAP83817.1 - 8.1 4.1 35.3 2.6 5.7 9.8 3.0 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family Laminin_I PF06008.9 GAP83817.1 - 8.3 5.6 47.4 30 3.8 26.4 2.3 1 1 1 2 2 2 0 Laminin Domain I Bacillus_HBL PF05791.6 GAP83817.1 - 8.9 5.6 21.9 13 5.0 2.2 3.5 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) CHD5 PF04420.9 GAP83818.1 - 2e-54 183.5 0.6 3.5e-54 182.8 0.4 1.4 1 0 0 1 1 1 1 CHD5-like protein MADF_DNA_bdg PF10545.4 GAP83818.1 - 0.13 12.4 1.4 0.24 11.5 1.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PPTA PF01239.17 GAP83819.1 - 9.6e-05 21.5 8.6 0.18 11.2 0.4 4.2 4 0 0 4 4 4 2 Protein prenyltransferase alpha subunit repeat Asp PF00026.18 GAP83820.1 - 3.2e-73 246.7 5.0 4.1e-73 246.4 3.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAP83820.1 - 6.1e-12 45.7 0.8 1.1e-11 44.9 0.1 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 GAP83820.1 - 0.00016 22.1 0.4 0.04 14.4 0.1 2.8 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 GAP83820.1 - 0.00022 20.8 0.0 0.0005 19.6 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Aa_trans PF01490.13 GAP83821.1 - 1.3e-70 238.0 28.7 1.6e-70 237.6 19.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SPT6_acidic PF14632.1 GAP83821.1 - 1.9 8.6 6.6 3.3 7.9 4.5 1.2 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Ras PF00071.17 GAP83823.1 - 7.4e-56 188.0 0.0 8.5e-56 187.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAP83823.1 - 1.9e-15 57.4 0.0 2.7e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAP83823.1 - 2.8e-07 29.9 0.0 4.6e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 GAP83823.1 - 0.00086 18.5 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 GAP83823.1 - 0.02 14.0 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region KOW PF00467.24 GAP83824.1 - 0.0002 20.9 0.1 0.00048 19.7 0.1 1.6 1 0 0 1 1 1 1 KOW motif IKI3 PF04762.7 GAP83825.1 - 0 1049.7 0.0 0 1049.4 0.0 1.1 1 0 0 1 1 1 1 IKI3 family WD40 PF00400.27 GAP83825.1 - 1.4 8.9 5.4 63 3.6 0.0 5.2 6 0 0 6 6 6 0 WD domain, G-beta repeat TPR_1 PF00515.23 GAP83825.1 - 2.1 8.0 4.6 10 5.9 1.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAP83825.1 - 6.3 6.9 8.4 14 5.9 2.2 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3984 PF13136.1 GAP83826.1 - 7e-62 209.5 12.3 9.8e-62 209.0 8.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) Hpt PF01627.18 GAP83827.1 - 2.8e-15 56.0 0.0 3.9e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Hpt domain AKAP7_NLS PF10469.4 GAP83828.1 - 6.3e-31 107.7 0.0 7.7e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 GAP83828.1 - 0.00018 21.2 0.0 0.00025 20.8 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 GAP83828.1 - 0.018 15.0 0.0 6.7 6.7 0.0 3.0 2 1 1 3 3 3 0 LigT like Phosphoesterase ERM PF00769.14 GAP83829.1 - 0.0034 16.9 11.4 0.054 13.0 7.5 2.2 1 1 1 2 2 2 2 Ezrin/radixin/moesin family TBPIP PF07106.8 GAP83829.1 - 0.0088 15.6 4.2 0.0088 15.6 2.9 2.2 1 1 1 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 GAP83829.1 - 0.014 14.9 9.5 0.03 13.9 6.6 1.5 1 0 0 1 1 1 0 IncA protein Bap31 PF05529.7 GAP83829.1 - 0.02 14.3 4.5 0.1 12.0 1.5 2.4 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like Reo_sigmaC PF04582.7 GAP83829.1 - 0.024 13.8 1.7 0.044 12.9 0.2 1.9 2 1 0 2 2 2 0 Reovirus sigma C capsid protein IFT57 PF10498.4 GAP83829.1 - 0.034 12.8 5.7 0.06 12.0 4.0 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 AAA_13 PF13166.1 GAP83829.1 - 0.049 12.0 4.5 0.071 11.5 3.1 1.1 1 0 0 1 1 1 0 AAA domain BRE1 PF08647.6 GAP83829.1 - 0.065 13.2 3.9 0.11 12.4 0.5 2.5 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase FlxA PF14282.1 GAP83829.1 - 0.11 12.4 3.7 0.3 11.0 1.5 2.5 1 1 1 2 2 2 0 FlxA-like protein Cast PF10174.4 GAP83829.1 - 0.13 10.3 15.5 0.0086 14.1 6.8 1.7 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone ADIP PF11559.3 GAP83829.1 - 0.13 12.1 13.6 0.41 10.5 5.0 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Ax_dynein_light PF10211.4 GAP83829.1 - 0.23 11.2 7.6 1.8 8.3 1.0 2.4 2 0 0 2 2 2 0 Axonemal dynein light chain Nup54 PF13874.1 GAP83829.1 - 0.23 11.1 5.6 0.47 10.1 3.9 1.6 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 CENP-F_leu_zip PF10473.4 GAP83829.1 - 0.23 11.3 10.9 0.48 10.2 7.5 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V_ATPase_I PF01496.14 GAP83829.1 - 0.26 9.0 2.7 0.32 8.7 1.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MscS_porin PF12795.2 GAP83829.1 - 0.26 10.5 12.9 0.12 11.6 6.9 1.9 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Bacillus_HBL PF05791.6 GAP83829.1 - 0.31 10.3 3.2 2.3 7.5 2.2 2.1 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF2959 PF11172.3 GAP83829.1 - 0.33 10.6 11.9 0.071 12.8 4.6 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2959) Spc7 PF08317.6 GAP83829.1 - 0.43 9.2 10.7 0.21 10.1 5.2 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein FlaF PF07309.6 GAP83829.1 - 0.86 9.4 7.0 0.14 12.0 0.6 2.5 2 1 1 3 3 3 0 Flagellar protein FlaF Atg14 PF10186.4 GAP83829.1 - 2 7.2 11.8 11 4.8 8.0 2.1 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 GAP83829.1 - 5.1 6.9 10.2 3.7 7.4 1.6 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.7 GAP83829.1 - 6.1 6.6 12.4 5.8 6.6 7.5 1.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.17 GAP83829.1 - 6.4 6.8 11.8 5.4 7.0 0.2 3.0 2 1 1 3 3 2 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.5 GAP83829.1 - 9.6 6.3 7.5 4.1 7.5 2.7 2.2 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4140 PF13600.1 GAP83829.1 - 9.9 6.6 12.1 16 5.9 2.1 2.9 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) HSP70 PF00012.15 GAP83830.1 - 3.9e-07 28.3 0.2 2.5e-06 25.7 0.0 1.9 2 0 0 2 2 2 2 Hsp70 protein Pkinase PF00069.20 GAP83831.1 - 1e-59 201.8 0.0 1.5e-59 201.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP83831.1 - 2.1e-31 108.9 0.0 1.2e-29 103.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 GAP83831.1 - 0.04 12.7 0.0 0.056 12.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Stc1 PF12898.2 GAP83832.1 - 2.9e-13 49.6 12.0 5.4e-13 48.8 8.3 1.5 1 0 0 1 1 1 1 Stc1 domain MIP-T3 PF10243.4 GAP83833.1 - 2.1 6.7 29.6 0.49 8.8 17.0 2.3 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Sugar_tr PF00083.19 GAP83834.1 - 1.6e-89 300.5 17.9 1.9e-89 300.3 12.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP83834.1 - 3.5e-22 78.5 32.4 7.6e-19 67.6 2.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PLDc_N PF13396.1 GAP83835.1 - 1.8e-13 49.8 2.1 1.8e-13 49.8 1.4 1.8 2 0 0 2 2 2 1 Phospholipase_D-nuclease N-terminal DUF3951 PF13131.1 GAP83835.1 - 0.012 15.4 3.3 0.036 13.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) DUF3169 PF11368.3 GAP83835.1 - 0.041 13.0 0.1 0.059 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Pox_A14 PF05767.7 GAP83835.1 - 0.053 13.4 0.2 0.077 12.9 0.2 1.3 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Cytochrom_B561 PF03188.11 GAP83835.1 - 0.071 12.9 1.1 0.88 9.3 0.1 2.0 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 DUF3976 PF13121.1 GAP83835.1 - 0.1 12.4 0.6 0.1 12.4 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3976) RSN1_TM PF13967.1 GAP83835.1 - 0.11 12.0 0.5 0.16 11.5 0.4 1.3 1 1 0 1 1 1 0 Late exocytosis, associated with Golgi transport DUF2207 PF09972.4 GAP83835.1 - 0.25 9.9 0.7 0.25 9.8 0.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3784 PF12650.2 GAP83835.1 - 0.37 10.7 4.3 0.092 12.6 0.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF805 PF05656.9 GAP83835.1 - 6.5 6.6 6.1 19 5.0 4.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF805) CMAS PF02353.15 GAP83836.1 - 1.5e-17 63.5 0.0 2.3e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 GAP83836.1 - 2.3e-14 53.4 0.0 3.5e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP83836.1 - 6.6e-11 42.5 0.0 1.8e-10 41.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP83836.1 - 7.3e-10 38.6 0.0 3.7e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 GAP83836.1 - 8.7e-09 35.7 0.0 5.2e-08 33.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP83836.1 - 1.4e-07 32.0 0.0 2.9e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP83836.1 - 2.4e-07 31.0 0.0 7.3e-07 29.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAP83836.1 - 0.00019 20.8 0.0 0.00043 19.6 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 GAP83836.1 - 0.00026 20.9 0.0 0.00041 20.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 GAP83836.1 - 0.0012 18.2 0.1 0.029 13.7 0.0 2.6 3 1 1 4 4 4 1 Methionine biosynthesis protein MetW DOT1 PF08123.8 GAP83836.1 - 0.031 13.5 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 PCMT PF01135.14 GAP83836.1 - 0.12 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GFO_IDH_MocA PF01408.17 GAP83837.1 - 7.3e-21 74.9 0.1 1.1e-20 74.2 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 GAP83837.1 - 0.081 13.3 0.2 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Bac_rhodopsin PF01036.13 GAP83837.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacteriorhodopsin-like protein DUF4234 PF14018.1 GAP83837.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) Aldo_ket_red PF00248.16 GAP83838.1 - 1.1e-19 70.2 0.0 2e-19 69.4 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family Methyltransf_11 PF08241.7 GAP83839.1 - 2.8e-07 30.9 0.2 4.6e-05 23.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP83839.1 - 1e-06 28.5 0.0 9.8e-06 25.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP83839.1 - 0.00086 19.6 3.0 0.0022 18.2 2.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP83839.1 - 0.0017 18.7 0.0 0.0064 16.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP83839.1 - 0.0022 17.6 0.0 0.43 10.1 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 GAP83839.1 - 0.025 15.1 2.1 0.43 11.1 1.5 2.4 1 1 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 GAP83839.1 - 0.078 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 GAP83839.1 - 0.08 12.9 3.8 0.043 13.8 1.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain CAP_GLY PF01302.20 GAP83841.1 - 2.5e-22 78.3 0.9 4.2e-22 77.6 0.6 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 GAP83841.1 - 4.2e-22 78.1 0.0 7.1e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 GAP83841.1 - 2.5e-05 23.5 0.0 4.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family zf-RING_2 PF13639.1 GAP83842.1 - 1.5e-13 50.3 4.3 2.7e-13 49.4 3.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAP83842.1 - 6e-07 29.4 0.9 1.1e-06 28.6 0.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 GAP83842.1 - 9e-07 28.4 2.2 1.5e-06 27.7 1.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAP83842.1 - 8e-06 25.4 1.6 1.5e-05 24.6 1.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAP83842.1 - 1e-05 25.4 4.3 2.2e-05 24.3 3.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAP83842.1 - 0.00016 21.2 1.7 0.00031 20.3 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAP83842.1 - 0.0064 16.3 1.1 0.012 15.3 0.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 GAP83842.1 - 0.024 14.2 2.1 0.04 13.4 1.4 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 GAP83842.1 - 0.21 11.6 2.4 0.34 10.9 1.7 1.3 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 GAP83842.1 - 0.32 10.7 2.4 0.63 9.7 1.7 1.5 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 GAP83842.1 - 0.4 10.4 2.2 7.6 6.3 0.9 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF2360 PF10152.4 GAP83842.1 - 4.7 7.4 6.3 3.7 7.8 2.3 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Glyco_hydro_cc PF11790.3 GAP83843.1 - 1.9e-54 184.5 1.1 3e-54 183.9 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Zn_clus PF00172.13 GAP83844.1 - 4.6e-08 32.8 9.1 8.1e-08 32.0 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAP83844.1 - 0.00012 20.8 0.1 0.00019 20.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Macoilin PF09726.4 GAP83845.1 - 0.014 13.6 0.1 0.019 13.3 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF4614 PF15391.1 GAP83845.1 - 0.17 11.5 10.7 0.13 12.0 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) SR-25 PF10500.4 GAP83845.1 - 0.71 9.3 18.6 1.9 7.9 7.9 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TFIIF_alpha PF05793.7 GAP83845.1 - 3.3 5.9 4.6 5.5 5.2 3.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Med3 PF11593.3 GAP83845.1 - 3.5 6.7 10.1 9.3 5.3 0.1 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal BING4CT PF08149.6 GAP83846.1 - 1.6e-35 120.4 0.0 2.5e-34 116.6 0.0 3.0 4 0 0 4 4 4 1 BING4CT (NUC141) domain Coatomer_WDAD PF04053.9 GAP83846.1 - 0.00014 20.7 0.1 0.00028 19.8 0.0 1.4 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 GAP83846.1 - 0.0013 18.4 0.0 9.3 6.3 0.0 4.6 4 1 0 4 4 4 1 WD domain, G-beta repeat DUF663 PF04950.7 GAP83847.1 - 1.9e-106 355.3 0.0 2.6e-106 354.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 GAP83847.1 - 4.5e-20 70.9 0.0 1.1e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain cobW PF02492.14 GAP83848.1 - 9.3e-35 119.6 0.0 1.3e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 GAP83848.1 - 2.9e-05 22.9 1.2 0.00023 20.0 0.9 1.9 1 1 0 1 1 1 1 ArgK protein AAA_23 PF13476.1 GAP83848.1 - 0.0018 18.6 0.0 0.0025 18.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 GAP83848.1 - 0.047 13.0 0.4 0.079 12.3 0.3 1.5 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 GAP83848.1 - 0.16 11.3 0.1 0.36 10.2 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_21 PF13304.1 GAP83848.1 - 0.17 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain PSK PF06404.7 GAP83849.1 - 4.9 7.9 8.5 7.1 7.4 1.5 2.9 2 0 0 2 2 2 0 Phytosulfokine precursor protein (PSK) zf-HIT PF04438.11 GAP83850.1 - 1.4e-08 34.2 8.7 2e-08 33.7 6.1 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 GAP83850.1 - 0.041 13.7 5.0 0.063 13.1 3.5 1.3 1 0 0 1 1 1 0 MYND finger zf-B_box PF00643.19 GAP83850.1 - 0.2 11.5 4.7 0.33 10.8 3.2 1.3 1 0 0 1 1 1 0 B-box zinc finger Nfu_N PF08712.6 GAP83851.1 - 4.3e-28 96.7 0.0 1.6e-27 94.9 0.0 1.9 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 GAP83851.1 - 5.7e-21 74.0 0.1 9.4e-21 73.3 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain PSP1 PF04468.7 GAP83852.1 - 2e-30 104.6 0.4 2e-30 104.6 0.3 1.8 2 0 0 2 2 2 1 PSP1 C-terminal conserved region Rotavirus_VP3 PF06929.6 GAP83852.1 - 0.34 8.7 0.4 0.49 8.2 0.3 1.1 1 0 0 1 1 1 0 Rotavirus VP3 protein Ribosomal_L15e PF00827.12 GAP83854.1 - 2.5e-91 304.4 11.1 2.8e-91 304.2 7.7 1.0 1 0 0 1 1 1 1 Ribosomal L15 PUF PF00806.14 GAP83855.1 - 4.6e-58 189.5 11.2 3.3e-08 32.5 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat RNA_pol_Rpb2_6 PF00562.23 GAP83856.1 - 2.9e-117 391.7 0.0 4.5e-117 391.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 GAP83856.1 - 4.3e-52 175.9 0.3 4.4e-51 172.7 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 GAP83856.1 - 4.3e-29 100.5 0.2 1.1e-28 99.2 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 GAP83856.1 - 4.4e-27 94.7 0.0 1.1e-26 93.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 GAP83856.1 - 7.3e-21 73.7 0.0 1.7e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 GAP83856.1 - 3e-20 71.7 0.0 1.1e-19 70.0 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 GAP83856.1 - 7.8e-14 51.3 0.0 3.9e-13 49.1 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Rad51 PF08423.6 GAP83857.1 - 3.3e-21 75.3 0.0 7e-21 74.2 0.0 1.4 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.1 GAP83857.1 - 4.9e-11 42.4 0.1 1.2e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 GAP83857.1 - 1.1e-06 28.0 0.0 1.2e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 recA bacterial DNA recombination protein KaiC PF06745.8 GAP83857.1 - 9.3e-05 21.6 0.0 0.00019 20.6 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.1 GAP83857.1 - 0.0061 16.6 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Myosin_head PF00063.16 GAP83857.1 - 0.06 11.3 0.0 0.085 10.8 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) Podoplanin PF05808.6 GAP83858.1 - 0.018 14.6 0.6 0.03 13.8 0.4 1.3 1 0 0 1 1 1 0 Podoplanin SKG6 PF08693.5 GAP83858.1 - 0.03 13.6 0.4 0.063 12.6 0.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TrbC PF04956.8 GAP83858.1 - 0.048 13.6 0.7 0.089 12.8 0.0 1.7 2 0 0 2 2 2 0 TrbC/VIRB2 family Syndecan PF01034.15 GAP83858.1 - 0.12 12.0 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 Syndecan domain Secretin_N_2 PF07655.8 GAP83858.1 - 0.82 10.0 14.5 1.6 9.2 10.0 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Carn_acyltransf PF00755.15 GAP83859.1 - 1.1e-164 548.8 0.0 6.3e-149 496.7 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase Ras PF00071.17 GAP83862.1 - 1.3e-65 219.6 0.5 1.5e-65 219.4 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAP83862.1 - 1.2e-21 77.4 0.0 1.7e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAP83862.1 - 2.8e-16 59.2 0.1 3.4e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAP83862.1 - 2.1e-05 23.7 0.1 2.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAP83862.1 - 3e-05 23.5 0.1 6.2e-05 22.5 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAP83862.1 - 7.4e-05 22.6 0.0 0.00012 21.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 GAP83862.1 - 0.00038 19.7 0.0 0.00056 19.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 GAP83862.1 - 0.0013 18.9 0.0 0.0021 18.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 GAP83862.1 - 0.0014 18.7 0.0 0.095 12.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 GAP83862.1 - 0.0031 16.8 0.0 0.021 14.1 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 GAP83862.1 - 0.0069 15.5 0.0 0.02 14.0 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 GAP83862.1 - 0.015 15.3 0.1 0.084 12.8 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 GAP83862.1 - 0.022 14.6 0.2 0.067 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 GAP83862.1 - 0.039 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 GAP83862.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 GAP83862.1 - 0.09 13.0 0.0 0.14 12.4 0.0 1.5 1 1 0 1 1 1 0 ABC transporter Septin PF00735.13 GAP83862.1 - 0.093 11.7 0.0 0.2 10.6 0.0 1.5 1 0 0 1 1 1 0 Septin PduV-EutP PF10662.4 GAP83862.1 - 0.1 12.1 0.0 0.94 8.9 0.0 2.1 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IBR PF01485.16 GAP83864.1 - 6.1e-13 48.4 38.7 2.5e-07 30.4 3.6 4.2 4 0 0 4 4 4 3 IBR domain zf-RING_2 PF13639.1 GAP83864.1 - 0.0052 16.5 5.1 0.0052 16.5 3.6 3.9 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 GAP83864.1 - 0.017 14.7 2.2 0.017 14.7 1.5 4.3 5 1 0 5 5 5 0 Zinc finger, C3HC4 type (RING finger) Pox_vIL-18BP PF05566.7 GAP83864.1 - 0.035 14.1 0.1 0.16 11.9 0.1 2.1 1 0 0 1 1 1 0 Orthopoxvirus interleukin 18 binding protein DUF1563 PF07599.6 GAP83864.1 - 0.37 10.6 2.3 0.69 9.8 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) adh_short PF00106.20 GAP83865.1 - 6e-12 45.7 0.4 4.8e-11 42.8 0.0 2.4 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 GAP83865.1 - 3.8e-06 26.6 0.0 7.1e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAP83865.1 - 0.0066 15.9 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAP83865.1 - 0.053 13.5 0.8 1.1 9.1 0.2 2.8 2 1 0 2 2 2 0 NADH(P)-binding WD40 PF00400.27 GAP83866.1 - 4.2e-20 70.8 16.9 0.00043 20.0 0.1 6.6 6 1 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 GAP83866.1 - 0.00024 19.4 0.4 0.051 11.6 0.0 2.7 2 1 0 2 2 2 2 Nucleoporin Nup120/160 DUF627 PF04781.7 GAP83866.1 - 0.023 14.3 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF627) PQQ_3 PF13570.1 GAP83866.1 - 0.036 14.3 3.4 0.77 10.1 0.1 3.7 4 0 0 4 4 4 0 PQQ-like domain WD40 PF00400.27 GAP83867.1 - 3.2e-27 93.3 3.6 7.3e-10 38.3 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat DUF3639 PF12341.3 GAP83867.1 - 4.4e-10 39.3 3.3 5.3e-10 39.1 0.8 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3639) eIF2A PF08662.6 GAP83867.1 - 3.9e-05 23.4 0.1 0.00076 19.2 0.0 2.6 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 GAP83867.1 - 0.0011 17.8 0.0 0.002 16.9 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region IKI3 PF04762.7 GAP83867.1 - 0.0023 15.8 0.0 0.0038 15.1 0.0 1.5 1 0 0 1 1 1 1 IKI3 family DNA_pol_alpha_N PF12254.3 GAP83867.1 - 0.0029 17.3 0.5 0.0093 15.7 0.3 1.8 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal PD40 PF07676.7 GAP83867.1 - 0.0079 15.8 0.6 41 3.9 0.0 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat MRJP PF03022.11 GAP83867.1 - 0.18 10.9 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 Major royal jelly protein DUF3312 PF11768.3 GAP83867.1 - 0.19 9.9 0.0 1.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Abhydrolase_3 PF07859.8 GAP83870.1 - 5.4e-37 127.4 0.0 1.7e-26 93.1 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 GAP83870.1 - 0.019 13.6 0.0 0.029 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Lipase_3 PF01764.20 GAP83870.1 - 0.023 14.3 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Aminotran_3 PF00202.16 GAP83871.1 - 2.7e-95 319.1 0.0 3.3e-95 318.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Pyridoxal_deC PF00282.14 GAP83872.1 - 2.2e-58 197.4 0.0 3.3e-58 196.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain OKR_DC_1 PF01276.15 GAP83872.1 - 0.058 11.9 0.0 0.077 11.5 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Fungal_trans PF04082.13 GAP83875.1 - 5.9e-26 90.8 0.2 8.6e-26 90.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Shugoshin_N PF07558.6 GAP83875.1 - 0.0071 16.0 2.1 0.014 15.0 1.4 1.4 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Herpes_BLRF2 PF05812.7 GAP83875.1 - 0.048 13.4 0.2 0.088 12.6 0.2 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein RabGAP-TBC PF00566.13 GAP83876.1 - 3.7e-50 170.3 0.0 6.8e-50 169.5 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Fungal_trans PF04082.13 GAP83877.1 - 1.8e-29 102.4 0.0 3e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP83877.1 - 1.8e-05 24.5 11.1 3.1e-05 23.7 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3439 PF11921.3 GAP83877.1 - 7.6e-05 22.4 3.4 0.00015 21.4 2.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) APC8 PF04049.8 GAP83877.1 - 0.0094 15.6 1.6 1.6 8.4 0.9 2.3 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 Ctr PF04145.10 GAP83877.1 - 0.02 14.9 0.4 0.056 13.4 0.3 1.7 1 0 0 1 1 1 0 Ctr copper transporter family SSP160 PF06933.6 GAP83877.1 - 1.5 6.7 11.8 2.2 6.1 8.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PBP_sp32 PF07222.7 GAP83877.1 - 2.2 7.3 10.6 4 6.5 7.3 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Dicty_REP PF05086.7 GAP83877.1 - 3.4 5.3 3.3 5.6 4.5 2.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2076 PF09849.4 GAP83877.1 - 3.6 7.5 10.3 0.26 11.3 3.6 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) adh_short PF00106.20 GAP83878.1 - 2.7e-25 89.2 1.6 3.9e-25 88.6 1.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP83878.1 - 4.4e-23 82.3 0.1 6e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP83878.1 - 3.1e-16 59.5 0.3 4.2e-16 59.1 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAP83878.1 - 1.6e-08 34.3 0.0 2.1e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAP83878.1 - 0.0023 16.7 0.2 0.0031 16.2 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 GAP83878.1 - 0.003 16.4 0.0 0.0043 15.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 GAP83878.1 - 0.035 13.0 0.2 0.054 12.4 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase AAA_17 PF13207.1 GAP83879.1 - 3.8e-07 30.9 0.0 1.2e-06 29.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 GAP83879.1 - 8.2e-06 25.5 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 GAP83879.1 - 1e-05 25.4 0.4 0.00015 21.6 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAP83879.1 - 9.8e-05 22.4 0.1 0.00018 21.5 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 GAP83879.1 - 0.00026 20.1 0.1 0.00078 18.5 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 GAP83879.1 - 0.00059 19.5 0.2 0.00059 19.5 0.2 1.9 2 1 0 2 2 1 1 Part of AAA domain AAA PF00004.24 GAP83879.1 - 0.00071 19.7 0.0 0.001 19.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 GAP83879.1 - 0.001 18.0 0.2 0.0023 16.8 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.1 GAP83879.1 - 0.0013 19.0 0.0 0.0019 18.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAP83879.1 - 0.0017 18.5 0.0 0.0026 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 GAP83879.1 - 0.0022 16.9 0.0 0.0033 16.3 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain CobU PF02283.11 GAP83879.1 - 0.0066 15.8 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_25 PF13481.1 GAP83879.1 - 0.0069 15.8 0.2 0.014 14.8 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 GAP83879.1 - 0.0088 15.5 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain NTPase_1 PF03266.10 GAP83879.1 - 0.0093 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 NTPase AAA_28 PF13521.1 GAP83879.1 - 0.011 15.7 0.0 0.042 13.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain CoaE PF01121.15 GAP83879.1 - 0.021 14.2 0.1 1.4 8.2 0.1 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_5 PF07728.9 GAP83879.1 - 0.021 14.5 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 GAP83879.1 - 0.028 14.0 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.1 GAP83879.1 - 0.029 13.9 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 GAP83879.1 - 0.029 14.5 0.0 0.046 13.9 0.0 1.3 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.15 GAP83879.1 - 0.03 13.9 0.0 0.057 13.0 0.0 1.6 2 0 0 2 2 1 0 Adenylylsulphate kinase Mg_chelatase PF01078.16 GAP83879.1 - 0.032 13.4 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ArgK PF03308.11 GAP83879.1 - 0.036 12.8 0.0 0.055 12.2 0.0 1.2 1 0 0 1 1 1 0 ArgK protein ABC_tran PF00005.22 GAP83879.1 - 0.037 14.3 0.0 0.04 14.2 0.0 1.5 1 1 0 1 1 1 0 ABC transporter KTI12 PF08433.5 GAP83879.1 - 0.051 12.7 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_30 PF13604.1 GAP83879.1 - 0.066 12.7 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 GAP83879.1 - 0.07 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 GAP83879.1 - 0.092 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain DUF2075 PF09848.4 GAP83879.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.9 GAP83879.1 - 0.12 11.3 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_PrkA PF08298.6 GAP83879.1 - 0.13 10.9 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain adh_short_C2 PF13561.1 GAP83880.1 - 3.4e-30 105.6 1.4 4e-30 105.3 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAP83880.1 - 1.4e-27 96.6 2.6 1.7e-27 96.3 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP83880.1 - 8.6e-16 58.1 1.0 1.2e-15 57.6 0.7 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAP83880.1 - 0.00087 18.7 0.5 0.0013 18.2 0.3 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 GAP83880.1 - 0.009 15.9 1.1 0.026 14.4 0.7 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.1 GAP83880.1 - 0.027 14.4 1.5 0.065 13.2 1.0 1.7 1 1 0 1 1 1 0 NADH(P)-binding THF_DHG_CYH_C PF02882.14 GAP83880.1 - 0.054 12.5 0.2 0.11 11.5 0.1 1.6 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Saccharop_dh PF03435.13 GAP83880.1 - 0.057 12.3 1.2 0.2 10.6 0.3 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase GRDA PF04723.9 GAP83880.1 - 0.074 12.7 0.3 0.19 11.3 0.2 1.8 1 1 0 1 1 1 0 Glycine reductase complex selenoprotein A PHD PF00628.24 GAP83881.1 - 1.2 8.8 10.8 1.5 8.5 1.8 2.8 1 1 1 2 2 2 0 PHD-finger ADK_lid PF05191.9 GAP83881.1 - 5.6 6.7 6.9 0.98 9.1 1.2 2.3 2 0 0 2 2 2 0 Adenylate kinase, active site lid P21-Arc PF04062.9 GAP83883.1 - 4e-77 257.9 0.0 4.5e-77 257.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Hormone_3 PF00159.13 GAP83883.1 - 0.0081 16.1 1.5 0.017 15.1 1.0 1.4 1 0 0 1 1 1 1 Pancreatic hormone peptide Gcd10p PF04189.8 GAP83884.1 - 1.8e-69 234.1 0.0 3.4e-69 233.2 0.0 1.5 1 0 0 1 1 1 1 Gcd10p family Band_7 PF01145.20 GAP83885.1 - 1e-13 51.5 0.1 1e-13 51.5 0.1 3.0 2 1 0 2 2 2 1 SPFH domain / Band 7 family DUF4192 PF13830.1 GAP83885.1 - 0.32 10.6 11.0 0.49 10.0 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) WEMBL PF05701.6 GAP83887.1 - 3.4e-05 22.5 7.3 5.2e-05 21.9 5.0 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Spc7 PF08317.6 GAP83887.1 - 0.00011 20.9 2.4 0.00019 20.2 1.7 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Vps5 PF09325.5 GAP83887.1 - 0.0014 17.9 2.5 0.16 11.2 1.5 2.4 2 1 0 2 2 2 1 Vps5 C terminal like GAS PF13851.1 GAP83887.1 - 0.0031 16.7 4.1 0.0066 15.6 2.9 1.5 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF724 PF05266.9 GAP83887.1 - 0.0066 16.0 3.3 0.011 15.3 2.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF724) Vps53_N PF04100.7 GAP83887.1 - 0.035 12.9 0.8 0.066 11.9 0.6 1.4 1 0 0 1 1 1 0 Vps53-like, N-terminal ERM PF00769.14 GAP83887.1 - 0.037 13.5 5.1 0.062 12.8 3.6 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Ring_hydroxyl_B PF00866.13 GAP83887.1 - 0.067 12.8 0.7 0.19 11.4 0.2 1.9 2 0 0 2 2 2 0 Ring hydroxylating beta subunit V-SNARE_C PF12352.3 GAP83887.1 - 0.067 13.2 0.4 0.25 11.4 0.0 2.2 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Fib_alpha PF08702.5 GAP83887.1 - 0.11 12.6 1.0 0.24 11.5 0.7 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family IncA PF04156.9 GAP83887.1 - 0.12 12.0 1.7 0.3 10.6 1.0 1.8 1 1 1 2 2 2 0 IncA protein V_ATPase_I PF01496.14 GAP83887.1 - 0.16 9.7 1.4 0.22 9.3 0.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Laminin_II PF06009.7 GAP83887.1 - 0.18 11.5 5.4 0.27 10.9 1.9 2.2 2 0 0 2 2 2 0 Laminin Domain II APG6 PF04111.7 GAP83887.1 - 0.21 10.5 1.9 0.35 9.8 1.3 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Vps51 PF08700.6 GAP83887.1 - 0.23 11.3 3.7 0.38 10.6 0.7 2.7 3 0 0 3 3 3 0 Vps51/Vps67 Nup54 PF13874.1 GAP83887.1 - 0.94 9.1 4.7 1.8 8.2 1.6 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF972 PF06156.8 GAP83887.1 - 2.1 8.7 4.5 2.7 8.3 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) FlaC_arch PF05377.6 GAP83887.1 - 4.7 7.1 11.8 1.4 8.8 0.9 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Rep-A_N PF04057.7 GAP83888.1 - 0.0015 18.2 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain Glyco_hydro_61 PF03443.9 GAP83889.1 - 1.4e-05 24.9 0.2 0.00024 20.9 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 61 Shisa PF13908.1 GAP83891.1 - 1.7e-06 28.3 0.3 2.6e-06 27.7 0.2 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 GAP83891.1 - 0.00056 18.3 0.0 0.00064 18.1 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E RCR PF12273.3 GAP83891.1 - 0.00075 20.0 0.7 0.0013 19.2 0.5 1.5 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF1183 PF06682.7 GAP83891.1 - 0.00088 18.9 0.9 0.001 18.7 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) MLANA PF14991.1 GAP83891.1 - 0.0015 18.5 0.0 0.002 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein melan-A DUF4328 PF14219.1 GAP83891.1 - 0.0025 17.1 0.2 0.0035 16.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4328) Peptidase_M56 PF05569.6 GAP83891.1 - 0.0057 15.6 0.0 0.0067 15.4 0.0 1.2 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF2668 PF10873.3 GAP83891.1 - 0.0072 16.4 0.9 0.0082 16.3 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2668) SNARE_assoc PF09335.6 GAP83891.1 - 0.0085 16.2 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 1 SNARE associated Golgi protein DUF4229 PF14012.1 GAP83891.1 - 0.022 14.6 0.2 0.034 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Neur_chan_memb PF02932.11 GAP83891.1 - 0.023 14.6 0.0 0.025 14.4 0.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EphA2_TM PF14575.1 GAP83891.1 - 0.023 15.1 0.5 0.047 14.0 0.3 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1469 PF07332.6 GAP83891.1 - 0.023 14.4 0.3 0.034 13.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) P12 PF12669.2 GAP83891.1 - 0.026 14.7 0.4 0.042 14.0 0.2 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family Choline_transpo PF04515.7 GAP83891.1 - 0.035 12.8 0.0 0.044 12.5 0.0 1.1 1 0 0 1 1 1 0 Plasma-membrane choline transporter Vpu PF00558.14 GAP83891.1 - 0.045 13.3 0.1 0.071 12.6 0.1 1.3 1 0 0 1 1 1 0 Vpu protein IncA PF04156.9 GAP83891.1 - 0.045 13.3 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 IncA protein DUF2244 PF10003.4 GAP83891.1 - 0.049 13.0 0.0 0.068 12.5 0.0 1.1 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) DUF4117 PF13491.1 GAP83891.1 - 0.062 12.7 0.0 0.079 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4117) SKG6 PF08693.5 GAP83891.1 - 0.12 11.7 3.9 0.22 10.8 2.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.11 GAP83891.1 - 0.16 11.5 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family EssA PF10661.4 GAP83891.1 - 0.19 11.3 0.3 0.25 10.9 0.2 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA PMP1_2 PF08114.6 GAP83891.1 - 0.66 9.5 3.7 1.1 8.8 2.5 1.3 1 0 0 1 1 1 0 ATPase proteolipid family p450 PF00067.17 GAP83892.1 - 1.1e-82 278.0 0.0 1.4e-82 277.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF996 PF06195.8 GAP83893.1 - 0.0023 17.9 3.8 0.0026 17.7 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF996) UL2 PF08196.6 GAP83893.1 - 0.014 15.1 1.6 0.027 14.1 0.9 1.8 1 1 1 2 2 2 0 UL2 protein Sensor PF13796.1 GAP83893.1 - 0.04 13.5 1.1 0.056 13.0 0.8 1.2 1 0 0 1 1 1 0 Putative sensor DUF2207 PF09972.4 GAP83893.1 - 0.098 11.2 2.4 0.1 11.1 1.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MARVEL PF01284.18 GAP83893.1 - 0.11 12.3 4.3 0.15 11.8 3.0 1.2 1 0 0 1 1 1 0 Membrane-associating domain DUF3112 PF11309.3 GAP83893.1 - 0.21 11.3 4.2 0.28 10.9 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) DUF2417 PF10329.4 GAP83893.1 - 0.24 10.7 4.9 0.35 10.2 0.4 2.0 1 1 1 2 2 2 0 Region of unknown function (DUF2417) DUF4231 PF14015.1 GAP83893.1 - 0.51 10.3 3.1 0.62 10.0 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Sigma_reg_N PF13800.1 GAP83893.1 - 0.75 9.8 5.4 3 7.9 0.7 2.1 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Peptidase_M50 PF02163.17 GAP83893.1 - 0.92 8.4 3.0 2 7.3 0.6 1.9 2 0 0 2 2 2 0 Peptidase family M50 DUF1218 PF06749.7 GAP83893.1 - 1.4 9.4 5.5 14 6.2 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) DUF2116 PF09889.4 GAP83893.1 - 1.6 8.5 4.0 12 5.8 0.6 2.2 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF3671 PF12420.3 GAP83893.1 - 2.3 8.2 4.6 4.8 7.2 3.3 1.3 1 1 0 1 1 1 0 Protein of unknown function DUF4519 PF15012.1 GAP83893.1 - 3.4 7.6 7.2 3.7 7.5 0.9 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4519) T2SF PF00482.18 GAP83893.1 - 3.7 7.4 7.8 5.2 6.9 1.2 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Glyco_hydro_61 PF03443.9 GAP83894.1 - 1.6e-53 181.8 0.4 1.8e-53 181.5 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF3425 PF11905.3 GAP83895.1 - 6.1e-30 103.8 1.5 1.6e-29 102.5 1.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 GAP83895.1 - 0.02 14.8 4.0 0.036 14.0 2.8 1.4 1 0 0 1 1 1 0 bZIP transcription factor FAD_binding_4 PF01565.18 GAP83896.1 - 3.1e-19 68.8 3.6 6.6e-19 67.7 2.2 1.8 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP83896.1 - 0.00098 18.9 0.0 0.0024 17.7 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.11 GAP83897.1 - 8.5e-48 162.8 35.8 8.5e-48 162.8 24.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP83897.1 - 1.3e-13 50.3 20.0 4.2e-13 48.6 13.9 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter DUF869 PF05911.6 GAP83899.1 - 0.0013 17.1 2.6 0.0015 16.8 1.8 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) TMF_DNA_bd PF12329.3 GAP83899.1 - 0.079 12.7 1.1 0.16 11.7 0.2 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 GAP83899.1 - 0.088 11.8 2.8 0.1 11.5 1.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 CCDC155 PF14662.1 GAP83899.1 - 0.39 10.2 7.7 2.6 7.6 5.2 1.9 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 Phlebovirus_NSM PF07246.6 GAP83899.1 - 0.62 9.1 2.4 0.78 8.8 1.6 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M FUSC PF04632.7 GAP83899.1 - 2.3 6.5 16.7 2.9 6.2 11.5 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family ADIP PF11559.3 GAP83899.1 - 4.3 7.2 12.4 2.7 7.8 5.5 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.2 GAP83900.1 - 0.0039 17.0 8.0 0.0039 17.0 5.6 1.6 2 0 0 2 2 2 1 Tropomyosin like ATG16 PF08614.6 GAP83900.1 - 0.0044 16.8 4.0 0.0044 16.8 2.8 2.8 2 1 1 3 3 3 1 Autophagy protein 16 (ATG16) AAA_27 PF13514.1 GAP83900.1 - 0.02 12.6 7.8 0.031 11.9 5.4 1.3 1 0 0 1 1 1 0 AAA domain DUF4200 PF13863.1 GAP83900.1 - 0.034 14.1 6.1 0.075 12.9 4.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Spc7 PF08317.6 GAP83900.1 - 0.056 12.1 4.5 0.088 11.4 3.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein EzrA PF06160.7 GAP83900.1 - 0.059 11.5 4.0 0.16 10.0 1.5 1.9 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA IncA PF04156.9 GAP83900.1 - 0.076 12.6 7.3 0.01 15.4 2.2 1.6 2 0 0 2 2 2 0 IncA protein Tropomyosin PF00261.15 GAP83900.1 - 0.28 10.2 11.1 0.016 14.3 4.0 1.6 2 0 0 2 2 2 0 Tropomyosin TPR_MLP1_2 PF07926.7 GAP83900.1 - 0.35 10.6 12.7 0.06 13.0 2.2 2.6 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Laminin_II PF06009.7 GAP83900.1 - 0.43 10.3 6.1 11 5.7 0.0 2.6 2 1 1 3 3 3 0 Laminin Domain II FRG1 PF06229.7 GAP83900.1 - 0.51 9.7 5.5 1.7 8.0 0.6 2.3 2 0 0 2 2 2 0 FRG1-like family KIAA1430 PF13879.1 GAP83900.1 - 1 9.8 7.3 0.1 13.0 0.5 2.5 2 0 0 2 2 2 0 KIAA1430 homologue AAA_13 PF13166.1 GAP83900.1 - 1.9 6.8 11.2 0.1 11.0 3.0 1.8 2 0 0 2 2 2 0 AAA domain SlyX PF04102.7 GAP83900.1 - 2.3 8.6 4.9 1.8 9.0 0.1 2.8 3 0 0 3 3 3 0 SlyX DUF3416 PF11896.3 GAP83900.1 - 3.1 7.7 6.1 0.86 9.5 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3416) DBR1 PF05011.8 GAP83902.1 - 4.3e-18 65.5 0.0 1.1e-17 64.2 0.0 1.7 1 1 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 GAP83902.1 - 1.8e-11 43.8 0.8 3.8e-11 42.7 0.6 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase MIP-T3 PF10243.4 GAP83902.1 - 0.086 11.2 3.9 0.16 10.4 2.7 1.4 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF605 PF04652.11 GAP83902.1 - 4.8 6.4 17.1 6.8 5.9 11.8 1.2 1 0 0 1 1 1 0 Vta1 like Skp1_POZ PF03931.10 GAP83903.1 - 1.1e-12 47.8 0.0 1.4e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Ras PF00071.17 GAP83904.1 - 1.9e-47 160.6 0.0 2.6e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAP83904.1 - 2.3e-12 47.4 0.0 3.6e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAP83904.1 - 1.2e-05 24.6 0.0 3.2e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 GAP83904.1 - 0.063 12.4 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 GAP83904.1 - 0.093 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DASH_Dad1 PF08649.5 GAP83905.1 - 8.1e-24 83.0 0.8 1e-23 82.7 0.5 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 WVELL PF14043.1 GAP83905.1 - 0.088 12.4 0.1 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 WVELL protein Metallophos PF00149.23 GAP83906.1 - 4.8e-38 130.5 0.0 2.7e-33 115.0 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAP83906.1 - 0.021 14.6 0.0 0.091 12.5 0.0 2.0 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Smg4_UPF3 PF03467.10 GAP83907.1 - 2.3e-28 99.3 0.0 7.8e-28 97.6 0.0 1.9 2 0 0 2 2 2 1 Smg-4/UPF3 family RRM_6 PF14259.1 GAP83907.1 - 1.8e-06 27.8 0.0 3e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAP83907.1 - 1.3e-05 24.7 0.3 8.6e-05 22.0 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP83907.1 - 0.0086 15.9 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PBP1_TM PF14812.1 GAP83908.1 - 0.69 10.2 7.7 0.3 11.4 1.8 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BTV_NS2 PF04514.7 GAP83908.1 - 3.1 6.5 7.7 5.5 5.7 5.3 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 TPR_19 PF14559.1 GAP83909.1 - 0.0054 17.0 0.1 0.05 13.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-ZPR1 PF03367.8 GAP83910.1 - 2.5e-103 342.0 0.0 2.1e-51 173.2 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Rpr2 PF04032.11 GAP83911.1 - 1e-08 34.8 0.1 3.3e-08 33.2 0.1 1.8 1 1 1 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Mito_fiss_reg PF05308.6 GAP83911.1 - 0.093 12.0 5.1 0.13 11.6 3.5 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 GAP83911.1 - 1.3 8.2 5.8 2 7.6 4.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Abhydrolase_6 PF12697.2 GAP83912.1 - 9.6e-26 91.0 9.3 3.1e-25 89.4 6.4 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP83912.1 - 2e-17 63.3 0.0 4.8e-17 62.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP83912.1 - 2.2e-07 30.6 0.1 3.3e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 GAP83912.1 - 2.4e-06 27.3 0.2 2.4e-06 27.3 0.1 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Thioesterase PF00975.15 GAP83912.1 - 0.00011 22.5 0.4 0.00018 21.7 0.3 1.3 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.16 GAP83912.1 - 0.00067 18.9 0.9 0.064 12.4 0.4 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Lipase_3 PF01764.20 GAP83912.1 - 0.031 13.8 0.1 0.049 13.2 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 GAP83912.1 - 0.075 12.6 1.1 0.2 11.2 0.7 1.7 1 1 0 1 1 1 0 PGAP1-like protein DUF3467 PF11950.3 GAP83913.1 - 0.012 15.6 2.4 0.39 10.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3467) DUF3425 PF11905.3 GAP83914.1 - 1.6e-22 79.8 0.0 2.6e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Amidohydro_1 PF01979.15 GAP83915.1 - 2.7e-16 60.1 0.1 3.6e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 GAP83915.1 - 3.8e-09 36.9 6.5 2.4e-08 34.3 4.5 1.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 GAP83915.1 - 0.00031 20.0 1.6 0.002 17.4 1.1 2.3 1 1 0 1 1 1 1 Amidohydrolase family RRM_1 PF00076.17 GAP83916.1 - 7.2e-23 80.0 0.1 3.7e-14 52.0 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP83916.1 - 1.3e-19 69.9 0.0 4.3e-11 42.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP83916.1 - 3.3e-13 49.2 0.0 1.4e-06 28.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 GAP83916.1 - 0.018 14.7 0.0 5.3 6.7 0.0 2.3 2 0 0 2 2 2 0 DbpA RNA binding domain MFS_1 PF07690.11 GAP83917.1 - 6.6e-31 107.3 43.9 6.6e-31 107.3 30.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAP83917.1 - 3.1e-13 48.8 16.9 5.4e-13 48.0 10.5 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3574 PF12098.3 GAP83918.1 - 0.0014 18.1 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3574) DUF4443 PF14544.1 GAP83918.1 - 0.045 13.6 0.0 0.067 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4443) PAN_4 PF14295.1 GAP83920.1 - 5.8e-05 22.7 1.1 0.00011 21.8 0.8 1.4 1 0 0 1 1 1 1 PAN domain 2Fe-2S_thioredx PF01257.14 GAP83921.1 - 0.18 11.4 0.1 1.2 8.7 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like [2Fe-2S] ferredoxin SET PF00856.23 GAP83922.1 - 3e-09 37.3 0.9 3.6e-08 33.8 0.0 2.7 3 0 0 3 3 3 1 SET domain DUF3328 PF11807.3 GAP83925.1 - 7.2e-30 104.2 4.1 9.6e-30 103.8 2.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Lpp-LpqN PF10738.4 GAP83926.1 - 1.3 8.2 3.4 27 3.9 0.1 2.7 1 1 2 3 3 3 0 Probable lipoprotein LpqN ROKNT PF08067.6 GAP83926.1 - 8.8 6.2 17.3 9 6.2 0.3 4.6 1 1 4 6 6 6 0 ROKNT (NUC014) domain DUF3328 PF11807.3 GAP83927.1 - 1.2e-24 87.2 0.0 3.3e-24 85.7 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) FAD_binding_4 PF01565.18 GAP83928.1 - 3.5e-25 88.0 2.3 3.5e-25 88.0 1.6 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 GAP83928.1 - 0.00083 19.2 0.4 0.0024 17.7 0.3 1.8 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.11 GAP83929.1 - 7.6e-43 146.5 52.8 7.6e-43 146.5 36.6 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Methyltransf_33 PF10017.4 GAP83930.1 - 9e-25 87.0 0.1 1.3e-24 86.5 0.1 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent SRCR PF00530.13 GAP83930.1 - 0.026 14.8 0.1 0.065 13.5 0.1 1.6 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain Methyltransf_23 PF13489.1 GAP83930.1 - 0.11 12.2 0.0 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain AMP-binding PF00501.23 GAP83931.1 - 0 1230.5 0.0 1.6e-83 280.4 0.0 5.4 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.15 GAP83931.1 - 4.2e-207 685.8 0.0 1.6e-37 129.0 0.0 6.5 6 0 0 6 6 6 6 Condensation domain PP-binding PF00550.20 GAP83931.1 - 4.2e-57 190.3 1.8 4.5e-12 46.0 0.0 5.8 5 0 0 5 5 5 5 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 GAP83931.1 - 0.0022 18.2 0.0 1.5 9.1 0.0 3.2 2 0 0 2 2 2 2 HxxPF-repeated domain ArsC PF03960.10 GAP83931.1 - 0.58 10.2 1.1 6.7 6.8 0.0 3.0 3 0 0 3 3 3 0 ArsC family adh_short PF00106.20 GAP83932.1 - 4.2e-07 30.0 1.4 5e-07 29.7 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Acyl-CoA_dh_1 PF00441.19 GAP83935.1 - 2.2e-08 34.3 0.0 5.7e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 GAP83935.1 - 0.028 14.6 0.1 0.083 13.1 0.0 2.0 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Peptidase_S28 PF05577.7 GAP83936.1 - 1.6e-54 185.1 0.0 2.7e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 NB-ARC PF00931.17 GAP83937.1 - 0.0002 20.3 0.0 0.00027 19.8 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.1 GAP83938.1 - 6e-10 38.9 0.0 8.5e-07 28.8 0.0 2.7 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAP83938.1 - 8e-09 35.0 0.1 1.3e-05 24.7 0.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 GAP83938.1 - 7.6e-07 28.5 0.6 0.0033 17.2 0.1 4.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAP83938.1 - 0.00031 20.2 1.1 0.017 14.7 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAP83938.1 - 0.00094 19.6 0.3 7.7 7.4 0.1 3.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAP83938.1 - 0.011 16.0 0.3 0.055 13.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAP83938.1 - 0.045 14.2 0.1 15 6.3 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 GAP83938.1 - 0.057 13.3 0.2 20 5.2 0.0 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAP83938.1 - 0.08 13.6 0.3 7.6 7.3 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat Sugar_tr PF00083.19 GAP83939.1 - 8.6e-107 357.4 20.4 9.8e-107 357.3 14.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP83939.1 - 6.8e-20 71.0 40.8 3.4e-14 52.3 9.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 GAP83939.1 - 0.0015 16.6 0.3 0.0028 15.7 0.2 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 GAP83939.1 - 0.0037 15.4 0.7 0.0037 15.4 0.5 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector TPR_11 PF13414.1 GAP83940.1 - 1.8e-09 37.0 0.0 2.7e-08 33.3 0.0 2.8 3 0 0 3 3 3 1 TPR repeat UBA PF00627.26 GAP83940.1 - 4.4e-06 26.3 1.6 9.9e-06 25.2 0.0 2.4 3 0 0 3 3 3 1 UBA/TS-N domain TPR_12 PF13424.1 GAP83940.1 - 0.001 18.9 1.6 0.0068 16.3 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAP83940.1 - 0.0023 17.4 0.1 0.7 9.6 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat DnaJ PF00226.26 GAP83940.1 - 0.0033 17.1 0.5 0.014 15.0 0.0 2.2 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.12 GAP83940.1 - 0.004 16.9 0.0 0.32 11.0 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat Bacteriocin_IIc PF10439.4 GAP83940.1 - 5.1 7.3 5.6 9.6 6.4 0.8 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DUF1996 PF09362.5 GAP83941.1 - 1e-73 247.8 1.1 1.5e-73 247.3 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Voldacs PF03517.8 GAP83943.1 - 7.4e-23 80.8 0.1 1.4e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Zn_clus PF00172.13 GAP83946.1 - 6.2e-08 32.4 8.9 1.1e-07 31.6 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAP83946.1 - 0.00028 19.5 0.1 0.00036 19.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Transp_cyt_pur PF02133.10 GAP83947.1 - 9.6e-21 73.8 38.8 2.3e-20 72.5 26.9 1.6 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2672 PF10878.3 GAP83947.1 - 0.056 13.1 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2672) Pro-kuma_activ PF09286.6 GAP83948.1 - 8.5e-37 126.3 0.4 2.9e-35 121.3 0.0 2.8 2 1 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 GAP83948.1 - 2.6e-10 39.9 0.0 4.8e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Subtilase family SNAP-25 PF00835.14 GAP83949.1 - 0.17 12.6 2.5 11 6.9 0.4 2.9 2 1 0 2 2 2 0 SNAP-25 family Neisseria_TspB PF05616.8 GAP83949.1 - 2.1 6.5 5.9 2.6 6.3 4.1 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Glyco_hydro_18 PF00704.23 GAP83950.1 - 4.5e-09 36.2 0.0 9.4e-09 35.1 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 EXS PF03124.9 GAP83951.1 - 9.1e-94 314.2 29.3 1.1e-93 314.0 20.3 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 GAP83951.1 - 5.7e-59 200.1 0.0 8.4e-59 199.5 0.0 1.3 1 0 0 1 1 1 1 SPX domain FUR PF01475.14 GAP83951.1 - 0.14 12.0 0.1 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Ferric uptake regulator family p450 PF00067.17 GAP83952.1 - 2.5e-77 260.3 0.0 3.4e-77 259.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M18 PF02127.10 GAP83953.1 - 1.1e-126 422.8 0.0 1.4e-126 422.5 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) PAF-AH_p_II PF03403.8 GAP83954.1 - 2.1e-44 151.3 0.0 9.9e-41 139.2 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 GAP83954.1 - 1.2e-09 38.1 0.0 2.2e-09 37.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP83954.1 - 0.00061 19.7 0.3 0.0023 17.8 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 GAP83954.1 - 0.0042 16.0 0.0 0.0071 15.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 GAP83954.1 - 0.015 14.1 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Hydrolase_4 PF12146.3 GAP83954.1 - 0.036 13.9 0.0 0.092 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase DLH PF01738.13 GAP83954.1 - 0.047 12.9 0.0 0.099 11.9 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Sporozoite_P67 PF05642.6 GAP83954.1 - 0.28 8.9 4.1 0.42 8.4 2.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.12 GAP83954.1 - 0.53 10.0 16.4 1 9.1 11.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Menin PF05053.8 GAP83954.1 - 1.1 7.2 3.1 1.7 6.6 2.1 1.1 1 0 0 1 1 1 0 Menin Dicty_REP PF05086.7 GAP83954.1 - 1.6 6.3 5.4 2.1 5.9 3.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 GAP83954.1 - 9.2 6.0 11.0 23 4.7 7.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) GCD14 PF08704.5 GAP83955.1 - 5.9e-59 199.5 0.0 7.6e-41 140.2 0.0 2.7 2 1 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 GAP83955.1 - 0.062 13.3 0.0 0.15 12.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 GAP83955.1 - 0.076 13.5 0.0 0.2 12.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain tRNA-synt_1e PF01406.14 GAP83956.1 - 1e-112 376.1 0.0 1.7e-112 375.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 GAP83956.1 - 2.4e-06 26.4 0.8 0.017 13.8 0.1 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.6 GAP83956.1 - 0.024 14.8 0.7 0.056 13.6 0.0 2.0 2 0 0 2 2 2 0 DALR domain HTH_34 PF13601.1 GAP83956.1 - 0.085 12.8 0.1 0.54 10.3 0.0 2.3 2 0 0 2 2 2 0 Winged helix DNA-binding domain LSM PF01423.17 GAP83957.1 - 4.7e-15 54.8 0.2 6.1e-15 54.5 0.2 1.1 1 0 0 1 1 1 1 LSM domain tRNA-synt_1b PF00579.20 GAP83958.1 - 3.1e-18 65.9 0.0 1.6e-17 63.6 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF3176 PF11374.3 GAP83960.1 - 9.8e-31 105.9 1.0 1.8e-30 105.0 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) BRCT PF00533.21 GAP83961.1 - 0.029 14.5 0.0 0.16 12.0 0.0 2.3 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain Chorion_3 PF05387.6 GAP83963.1 - 4 6.8 11.2 5.5 6.3 7.8 1.1 1 0 0 1 1 1 0 Chorion family 3 Zw10 PF06248.8 GAP83964.1 - 2.4e-15 55.7 3.5 9.5e-13 47.1 0.8 2.6 2 1 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 GAP83964.1 - 3.3e-06 26.4 0.0 1e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal Peptidase_M16_C PF05193.16 GAP83965.1 - 8e-20 71.2 0.0 1.3e-13 51.0 0.0 3.7 3 1 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 GAP83965.1 - 1.8e-06 27.8 0.1 1.1e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Polyketide_cyc2 PF10604.4 GAP83966.1 - 0.00058 20.0 2.0 0.013 15.6 1.4 2.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF3681 PF12442.3 GAP83967.1 - 0.00074 19.6 0.0 0.0019 18.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3681) Virul_fac_BrkB PF03631.10 GAP83967.1 - 4.9 6.4 20.3 5.8 6.1 9.5 2.8 2 1 0 2 2 2 0 Virulence factor BrkB DIOX_N PF14226.1 GAP83968.1 - 1.3e-19 70.8 0.0 2.9e-19 69.7 0.0 1.6 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAP83968.1 - 3.6e-18 65.6 0.0 5.4e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_61 PF03443.9 GAP83969.1 - 2.9e-54 184.1 0.2 3.4e-54 183.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 zf-C2H2_4 PF13894.1 GAP83970.1 - 4.3e-07 29.8 14.7 0.00029 20.9 0.3 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-Di19 PF05605.7 GAP83970.1 - 0.0029 17.7 6.3 1.3 9.2 0.1 3.9 3 1 1 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 GAP83970.1 - 0.52 10.7 0.1 0.52 10.7 0.1 4.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type Peptidase_M35 PF02102.10 GAP83973.1 - 8.6e-64 215.4 16.5 9.5e-64 215.3 11.4 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 GAP83973.1 - 3.3e-13 50.4 0.8 5.8e-13 49.5 0.5 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase PA14_2 PF10528.4 GAP83973.1 - 0.003 17.5 2.7 0.3 11.0 0.1 2.6 2 0 0 2 2 2 2 GLEYA domain CARDB PF07705.6 GAP83973.1 - 0.74 9.9 3.7 3.4 7.7 0.2 3.0 2 2 0 2 2 2 0 CARDB DUF2823 PF11034.3 GAP83977.1 - 2.5e-30 104.3 14.3 2.8e-30 104.2 9.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) EBP PF05241.7 GAP83978.1 - 1.3e-64 216.7 11.7 1.6e-64 216.5 8.1 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF2781 PF10914.3 GAP83978.1 - 0.023 14.4 5.4 0.055 13.2 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) Gln-synt_C PF00120.19 GAP83979.1 - 1.6e-57 194.5 0.0 2e-57 194.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Med15 PF09606.5 GAP83981.1 - 0.00025 19.4 43.0 0.00026 19.3 29.8 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal RR_TM4-6 PF06459.7 GAP83981.1 - 0.13 12.1 6.4 0.15 11.9 4.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ndc1_Nup PF09531.5 GAP83981.1 - 0.16 10.3 6.5 0.18 10.1 4.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DDRGK PF09756.4 GAP83981.1 - 0.22 10.9 22.3 0.31 10.4 15.4 1.2 1 0 0 1 1 1 0 DDRGK domain eIF-3_zeta PF05091.7 GAP83981.1 - 0.34 9.4 17.0 0.41 9.2 11.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur_chan_memb PF02932.11 GAP83981.1 - 0.49 10.2 10.0 0.74 9.6 6.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.4 GAP83981.1 - 0.96 7.6 44.0 1.2 7.3 30.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 GAP83981.1 - 1.3 8.6 17.4 1.9 8.1 12.1 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Hid1 PF12722.2 GAP83981.1 - 2.2 5.8 14.4 2.7 5.5 10.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM60A PF15396.1 GAP83981.1 - 2.8 7.6 13.1 4.3 7.0 9.1 1.3 1 0 0 1 1 1 0 Protein Family FAM60A TFIIA PF03153.8 GAP83981.1 - 3.1 7.6 27.6 3.7 7.3 19.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Band_3_cyto PF07565.8 GAP83981.1 - 3.5 7.0 17.1 4.8 6.6 11.8 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain AUX_IAA PF02309.11 GAP83981.1 - 5.2 6.7 12.0 7.3 6.2 8.3 1.2 1 0 0 1 1 1 0 AUX/IAA family ADSL_C PF10397.4 GAP83982.1 - 3.1e-13 49.5 0.0 2.8e-12 46.4 0.0 2.5 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus Lyase_1 PF00206.15 GAP83982.1 - 3.8e-10 39.4 0.0 9.7e-10 38.1 0.0 1.7 1 1 0 1 1 1 1 Lyase RAI16-like PF10257.4 GAP83983.1 - 1.7e-76 257.4 3.2 2.7e-76 256.8 2.2 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DUF667 PF05018.8 GAP83983.1 - 0.0077 15.4 0.1 0.013 14.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF667) DLH PF01738.13 GAP83984.1 - 6.3e-12 45.2 0.2 2.1e-11 43.5 0.1 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 GAP83984.1 - 3.9e-08 33.1 0.1 5.6e-08 32.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP83984.1 - 0.0012 18.7 7.1 0.0029 17.5 4.9 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_23 PF13489.1 GAP83985.1 - 1.2e-20 73.8 0.1 3.8e-20 72.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP83985.1 - 1.3e-09 38.6 0.0 2e-08 34.8 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP83985.1 - 5.9e-09 35.6 0.0 1.5e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP83985.1 - 3e-06 27.6 0.0 1.4e-05 25.4 0.0 2.2 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP83985.1 - 5e-06 26.9 0.0 1.3e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP83985.1 - 0.0024 18.2 0.0 0.0061 16.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP83985.1 - 0.0078 16.2 0.0 0.02 14.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP83985.1 - 0.026 13.6 0.0 0.31 10.1 0.0 2.4 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 GAP83985.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.9 GAP83985.1 - 0.054 12.8 0.0 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_16 PF10294.4 GAP83985.1 - 0.07 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase DUF869 PF05911.6 GAP83985.1 - 0.07 11.3 0.3 0.1 10.8 0.2 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) DUF938 PF06080.7 GAP83985.1 - 0.074 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PrmA PF06325.8 GAP83985.1 - 0.079 12.0 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.11 GAP83985.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein B12-binding_2 PF02607.12 GAP83985.1 - 0.12 12.3 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 B12 binding domain MUG113 PF13455.1 GAP83986.1 - 2.3e-31 108.0 0.5 6e-31 106.7 0.1 1.9 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 GAP83986.1 - 5.7e-23 81.2 0.0 1.4e-22 79.9 0.0 1.7 1 0 0 1 1 1 1 T5orf172 domain Pyr_redox_3 PF13738.1 GAP83987.1 - 1e-26 94.2 0.1 1.5e-25 90.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAP83987.1 - 7e-16 57.5 0.0 2.1e-14 52.6 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 GAP83987.1 - 3.3e-15 55.8 1.1 4e-12 45.7 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAP83987.1 - 1.5e-13 51.1 0.0 1.8e-12 47.5 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAP83987.1 - 2.6e-08 34.1 0.4 0.0093 16.3 0.0 3.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP83987.1 - 6.7e-07 29.2 0.3 5e-06 26.4 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAP83987.1 - 2.6e-06 26.6 7.7 0.16 10.8 0.0 4.2 3 1 1 4 4 4 2 FAD dependent oxidoreductase Shikimate_DH PF01488.15 GAP83987.1 - 4e-06 26.9 0.1 0.01 15.9 0.0 2.9 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 GAP83987.1 - 4.6e-06 26.5 0.5 0.075 12.8 0.0 2.4 2 0 0 2 2 2 2 ThiF family 2-Hacid_dh_C PF02826.14 GAP83987.1 - 1.2e-05 24.5 0.1 0.056 12.6 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 GAP83987.1 - 1.3e-05 24.2 0.3 0.0025 16.7 0.1 2.4 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 GAP83987.1 - 2.5e-05 23.5 1.0 2.5e-05 23.5 0.7 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 GAP83987.1 - 3.6e-05 23.5 3.1 0.17 11.6 0.4 3.8 3 1 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.9 GAP83987.1 - 0.0005 18.6 2.7 0.2 10.1 0.6 2.9 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.12 GAP83987.1 - 0.00074 18.6 2.4 0.23 10.5 0.1 3.6 4 0 0 4 4 4 1 Thi4 family TrkA_N PF02254.13 GAP83987.1 - 0.001 19.0 0.3 1.7 8.6 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain Lycopene_cycl PF05834.7 GAP83987.1 - 0.0012 17.9 1.1 0.089 11.6 0.0 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_oxidored PF12831.2 GAP83987.1 - 0.0018 17.4 1.0 0.006 15.7 0.7 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.11 GAP83987.1 - 0.0031 16.9 0.2 2.7 7.3 0.0 3.1 2 1 1 3 3 3 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.7 GAP83987.1 - 0.0043 16.4 0.1 0.49 9.7 0.0 2.4 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 GAP83987.1 - 0.0066 16.1 0.5 0.28 10.8 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 GAP83987.1 - 0.015 14.1 3.8 1.9 7.2 0.1 3.8 4 0 0 4 4 4 0 Glucose inhibited division protein A Amino_oxidase PF01593.19 GAP83987.1 - 0.022 13.8 0.9 0.79 8.7 0.0 2.4 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.1 GAP83987.1 - 0.058 13.6 0.0 5 7.4 0.0 2.5 3 0 0 3 3 2 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 GAP83987.1 - 0.16 11.7 0.3 3 7.5 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.16 GAP83987.1 - 0.83 9.1 4.9 12 5.3 0.0 3.1 4 0 0 4 4 4 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.11 GAP83988.1 - 1.5e-35 122.5 61.0 1.5e-35 122.5 42.3 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAP83988.1 - 1.9e-11 42.9 15.1 3.9e-11 41.8 10.5 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Zn_clus PF00172.13 GAP83990.1 - 1.2 9.1 14.7 3.4 7.6 10.2 1.8 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain FemAB PF02388.11 GAP83991.1 - 0.0043 15.7 1.0 0.0043 15.7 0.7 2.5 3 0 0 3 3 3 1 FemAB family GAS PF13851.1 GAP83991.1 - 0.069 12.3 14.2 0.44 9.7 0.6 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Inhibitor_I68 PF10468.4 GAP83991.1 - 0.21 11.8 0.0 0.98 9.6 0.0 2.0 2 0 0 2 2 2 0 Carboxypeptidase inhibitor I68 Seryl_tRNA_N PF02403.17 GAP83991.1 - 0.25 11.3 19.9 0.99 9.4 4.7 3.0 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Macoilin PF09726.4 GAP83991.1 - 0.96 7.6 20.9 4.4 5.4 13.6 2.1 2 0 0 2 2 2 0 Transmembrane protein Nexin_C PF08628.7 GAP83991.1 - 9 6.4 9.0 4.5 7.4 0.2 3.4 2 1 0 3 3 3 0 Sorting nexin C terminal 4HBT_2 PF13279.1 GAP83992.1 - 8.4e-16 58.5 0.1 1.2e-15 58.0 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 GAP83992.1 - 0.0099 15.9 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily Sec5 PF15469.1 GAP83992.1 - 0.084 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec5 Complex1_LYR_2 PF13233.1 GAP83993.1 - 4.9e-06 26.9 0.3 5.5e-06 26.8 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 GAP83993.1 - 0.0052 16.5 0.1 0.0086 15.8 0.0 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAP83993.1 - 0.0054 16.8 0.1 0.0075 16.4 0.1 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Methyltransf_25 PF13649.1 GAP83994.1 - 2.3e-11 43.9 0.0 4.4e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP83994.1 - 7e-11 42.4 0.0 1.6e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP83994.1 - 8.8e-09 35.1 0.0 1.6e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP83994.1 - 4.4e-08 33.6 0.0 7.9e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP83994.1 - 7.4e-07 28.5 0.0 1.1e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 GAP83994.1 - 5.3e-06 26.2 0.0 1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP83994.1 - 4.1e-05 23.9 0.0 0.00014 22.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP83994.1 - 5.2e-05 23.2 0.0 0.00019 21.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 GAP83994.1 - 0.0014 18.3 0.1 0.0062 16.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 GAP83994.1 - 0.028 13.7 0.0 0.075 12.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 GAP83994.1 - 0.11 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Exo_endo_phos PF03372.18 GAP83995.1 - 9.4e-22 78.1 0.1 1.5e-21 77.4 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 GAP83995.1 - 2.5e-15 55.6 4.9 1.2e-08 34.3 0.3 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAP83995.1 - 3e-08 33.2 2.0 6.4e-08 32.2 1.4 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 GAP83995.1 - 1.8e-07 30.1 5.6 0.024 14.5 0.1 4.6 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 GAP83995.1 - 0.0098 15.9 7.0 0.42 11.0 0.2 4.1 4 0 0 4 4 4 1 Leucine rich repeat LRR_6 PF13516.1 GAP83995.1 - 0.15 12.2 1.8 14 6.1 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich repeat 2OG-FeII_Oxy PF03171.15 GAP83996.1 - 5.3e-14 52.2 0.0 8.6e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 GAP83996.1 - 8.3e-10 39.2 0.0 1.4e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Spexin PF15171.1 GAP83996.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Neuropeptide secretory protein family, NPQ, spexin SKG6 PF08693.5 GAP83997.1 - 2.1 7.7 8.3 5.2 6.4 0.3 2.8 3 0 0 3 3 3 0 Transmembrane alpha-helix domain FtsH_ext PF06480.10 GAP83999.1 - 0.089 12.9 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 FtsH Extracellular Gemini_mov PF01708.11 GAP83999.1 - 0.092 12.3 0.1 0.092 12.3 0.1 2.0 2 0 0 2 2 2 0 Geminivirus putative movement protein Ribonuclease_T2 PF00445.13 GAP84000.1 - 2.1e-35 122.0 0.1 2.9e-35 121.6 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family TPR_MLP1_2 PF07926.7 GAP84001.1 - 0.013 15.2 2.7 0.013 15.2 1.8 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Cortex-I_coil PF09304.5 GAP84001.1 - 3.5 7.7 6.8 22 5.1 0.6 2.8 2 1 0 2 2 2 0 Cortexillin I, coiled coil DUF676 PF05057.9 GAP84002.1 - 2.7e-06 26.8 0.1 4.8e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 GAP84002.1 - 1.3e-05 25.0 0.0 2.8e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAP84002.1 - 1.9e-05 24.3 0.2 4.3e-05 23.2 0.1 1.6 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 GAP84002.1 - 3.4e-05 23.8 0.1 7.1e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Macoilin PF09726.4 GAP84002.1 - 0.004 15.5 3.9 0.0053 15.1 2.7 1.2 1 0 0 1 1 1 1 Transmembrane protein Abhydrolase_1 PF00561.15 GAP84002.1 - 0.007 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2305 PF10230.4 GAP84002.1 - 0.012 15.0 0.1 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 GAP84002.1 - 0.017 14.7 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) UPF0227 PF05728.7 GAP84002.1 - 0.028 14.1 0.0 0.073 12.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF900 PF05990.7 GAP84002.1 - 0.041 13.2 0.0 0.16 11.2 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Thioesterase PF00975.15 GAP84002.1 - 0.058 13.5 2.5 0.42 10.8 0.0 2.7 2 1 0 2 2 2 0 Thioesterase domain F-box-like PF12937.2 GAP84003.1 - 0.00038 20.1 0.1 0.001 18.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 GAP84003.1 - 0.015 15.0 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain LRR_4 PF12799.2 GAP84003.1 - 0.049 13.2 3.0 0.33 10.6 0.1 2.9 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) Rox3 PF08633.5 GAP84004.1 - 6.6e-47 160.3 1.5 2.8e-45 155.0 0.1 2.1 2 0 0 2 2 2 2 Rox3 mediator complex subunit UQ_con PF00179.21 GAP84005.1 - 2.5e-36 124.1 0.0 3.2e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAP84005.1 - 0.059 13.1 0.0 0.2 11.4 0.0 1.8 1 1 0 1 1 1 0 Prokaryotic E2 family B UBA_4 PF14555.1 GAP84006.1 - 4.2e-05 22.9 0.1 0.0001 21.7 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.26 GAP84006.1 - 0.00072 19.3 0.2 0.0022 17.7 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain DnaJ PF00226.26 GAP84007.1 - 7.6e-28 96.0 3.0 1.3e-27 95.3 2.1 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 GAP84007.1 - 5.3e-20 71.0 3.8 1.1e-17 63.6 0.1 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain Epimerase PF01370.16 GAP84008.1 - 6.9e-05 22.3 0.0 0.00028 20.3 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAP84008.1 - 0.00017 20.6 0.0 0.0008 18.4 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 GAP84008.1 - 0.00087 19.3 0.0 0.008 16.2 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding PBP PF01161.15 GAP84009.1 - 9.4e-13 48.2 0.0 1.1e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ribosomal_60s PF00428.14 GAP84009.1 - 0.0096 16.3 4.7 0.0096 16.3 3.3 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein Aminotran_1_2 PF00155.16 GAP84010.1 - 8e-43 146.7 0.0 1e-42 146.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II MCLC PF05934.6 GAP84011.1 - 3 6.0 6.3 4.3 5.5 4.4 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) TauD PF02668.11 GAP84013.1 - 1.3e-23 84.0 0.0 2.3e-23 83.1 0.0 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Methyltransf_2 PF00891.13 GAP84014.1 - 1.2e-20 73.7 0.0 1.4e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 GAP84014.1 - 0.042 13.4 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 GAP84014.1 - 0.05 14.1 0.0 0.073 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ank_2 PF12796.2 GAP84015.1 - 3.8e-85 280.3 0.6 2e-13 50.4 0.0 7.8 3 1 5 8 8 8 6 Ankyrin repeats (3 copies) Ank PF00023.25 GAP84015.1 - 4.5e-74 240.7 0.4 2.8e-06 26.8 0.0 14.8 15 0 0 15 15 15 12 Ankyrin repeat Ank_4 PF13637.1 GAP84015.1 - 6.3e-70 230.4 11.8 6.4e-09 36.0 0.0 9.7 2 1 11 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP84015.1 - 8.8e-51 164.8 7.4 0.0093 16.1 0.0 15.0 15 0 0 15 15 15 11 Ankyrin repeat Ank_5 PF13857.1 GAP84015.1 - 1.3e-39 133.3 11.7 8.9e-08 32.1 0.3 11.5 4 1 9 14 14 14 10 Ankyrin repeats (many copies) NACHT PF05729.7 GAP84015.1 - 1.9e-05 24.3 0.8 5.1e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 GAP84015.1 - 3.7e-05 23.8 2.1 6.9e-05 23.0 0.0 2.4 3 0 0 3 3 3 1 AAA domain DUF3734 PF12536.3 GAP84015.1 - 0.05 13.7 4.5 5.3 7.2 0.0 5.5 7 0 0 7 7 7 0 Patatin phospholipase Abhydrolase_6 PF12697.2 GAP84017.1 - 0.00064 19.6 0.0 0.00087 19.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 GAP84017.1 - 0.0022 17.3 0.0 0.0034 16.6 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 GAP84017.1 - 0.0079 15.9 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAP84017.1 - 0.033 13.7 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein LCAT PF02450.10 GAP84017.1 - 0.04 12.8 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Ser_hydrolase PF06821.8 GAP84017.1 - 0.073 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase CBS PF00571.23 GAP84019.1 - 2.4e-26 91.2 4.8 6.3e-10 38.6 0.0 4.3 4 0 0 4 4 4 4 CBS domain RhoGAP PF00620.22 GAP84020.1 - 2e-12 46.9 0.0 3.8e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Zn_clus PF00172.13 GAP84021.1 - 1.1e-06 28.4 11.3 1.1e-06 28.4 7.8 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_jaz PF12171.3 GAP84021.1 - 1.8e-05 24.6 0.9 0.00013 22.0 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAP84021.1 - 2.5e-05 24.3 0.1 8.6e-05 22.5 0.1 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 GAP84021.1 - 0.058 13.7 0.3 0.058 13.7 0.2 3.3 1 1 1 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 GAP84021.1 - 0.1 12.9 0.7 0.1 12.9 0.5 3.4 2 2 1 3 3 3 0 Zinc finger, C2H2 type Metallophos PF00149.23 GAP84023.1 - 4.7e-14 52.2 0.8 8.6e-14 51.4 0.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Nitroreductase PF00881.19 GAP84024.1 - 2.8e-11 43.5 0.0 3.7e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family FAD_binding_1 PF00667.15 GAP84025.1 - 3.9e-42 144.1 0.0 5.6e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 GAP84025.1 - 2.7e-08 34.3 0.0 5.3e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_3 PF01494.14 GAP84026.1 - 1.4e-12 47.4 7.1 1.2e-11 44.2 4.9 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAP84026.1 - 0.0001 22.2 1.5 0.00033 20.6 1.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAP84026.1 - 0.0015 17.5 4.0 0.013 14.4 1.3 2.4 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAP84026.1 - 0.0021 17.8 0.3 0.0061 16.3 0.2 1.8 1 0 0 1 1 1 1 FAD-NAD(P)-binding SE PF08491.5 GAP84026.1 - 0.02 13.6 0.0 0.061 12.1 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_2 PF07992.9 GAP84026.1 - 0.038 13.8 1.5 0.062 13.1 1.0 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAP84026.1 - 0.14 11.0 3.3 0.089 11.6 0.2 2.1 3 0 0 3 3 3 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAP84026.1 - 0.24 10.1 6.3 0.019 13.8 1.0 1.7 2 0 0 2 2 2 0 FAD binding domain p450 PF00067.17 GAP84027.1 - 1.9e-36 125.5 0.1 1.9e-26 92.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Mito_fiss_reg PF05308.6 GAP84027.1 - 1.6 8.0 6.0 4.1 6.6 4.0 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator NNMT_PNMT_TEMT PF01234.12 GAP84028.1 - 0.44 9.4 0.0 0.69 8.8 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family PBP PF01161.15 GAP84029.1 - 1.3e-13 51.0 0.0 1.8e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein 2-Hacid_dh_C PF02826.14 GAP84030.1 - 8.7e-52 174.8 0.0 1.4e-51 174.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAP84030.1 - 6.7e-16 57.9 0.0 9.6e-16 57.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 GAP84030.1 - 0.0012 18.6 0.0 0.003 17.4 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase TIMELESS PF04821.9 GAP84031.1 - 1.3e-88 296.7 4.2 7e-88 294.3 0.0 2.8 3 0 0 3 3 3 2 Timeless protein TIMELESS_C PF05029.8 GAP84031.1 - 2.1e-31 109.5 14.3 2.1e-31 109.5 9.9 4.1 2 1 1 3 3 3 1 Timeless protein C terminal region 3HCDH_N PF02737.13 GAP84032.1 - 3.3e-53 180.0 1.9 4.3e-53 179.6 1.3 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 GAP84032.1 - 1.5e-32 111.8 0.0 2.9e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 GAP84032.1 - 0.00026 20.8 0.6 0.00068 19.5 0.3 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.19 GAP84032.1 - 0.002 17.1 0.0 0.0028 16.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 GAP84032.1 - 0.0038 16.9 0.5 0.0081 15.8 0.3 1.7 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 GAP84032.1 - 0.0094 15.1 0.4 0.025 13.7 0.2 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 GAP84032.1 - 0.035 13.9 0.1 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 GAP84032.1 - 0.035 13.4 0.0 0.073 12.4 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 GAP84032.1 - 0.04 14.3 0.4 0.096 13.1 0.1 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP84032.1 - 0.1 12.6 1.2 0.21 11.6 0.6 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 GAP84032.1 - 0.17 12.3 3.7 0.15 12.5 0.8 2.3 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Fungal_trans PF04082.13 GAP84033.1 - 4.6e-38 130.5 0.7 9.6e-38 129.5 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP84033.1 - 3.8e-08 33.1 8.6 7.8e-08 32.1 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 GAP84034.1 - 1e-69 234.6 0.0 1.7e-69 233.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP84034.1 - 5.2e-36 124.0 0.0 9.2e-36 123.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP84034.1 - 0.00039 19.4 0.2 0.0034 16.3 0.0 2.0 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 GAP84034.1 - 0.002 17.2 0.1 0.004 16.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2011 PF09428.5 GAP84036.1 - 6.7e-25 87.4 15.6 1.7e-24 86.1 10.8 1.6 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF2011) NDT80_PhoG PF05224.7 GAP84038.1 - 8.8e-34 117.1 0.0 5.4e-33 114.5 0.0 2.1 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family IBR PF01485.16 GAP84040.1 - 8.9e-21 73.5 39.0 8.1e-14 51.2 2.7 4.3 3 1 1 4 4 4 3 IBR domain RWD PF05773.17 GAP84040.1 - 3.7e-18 65.4 0.0 6.4e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 GAP84040.1 - 6.4e-05 22.6 8.1 6.4e-05 22.6 5.6 3.5 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 GAP84040.1 - 0.00033 20.2 8.4 0.00033 20.2 5.8 4.2 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAP84040.1 - 0.00054 19.9 9.1 0.00054 19.9 6.3 4.0 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAP84040.1 - 0.011 15.4 3.5 0.011 15.4 2.4 2.7 3 0 0 3 3 3 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 GAP84040.1 - 0.017 14.9 5.3 0.017 14.9 3.7 4.3 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING Baculo_RING PF05883.6 GAP84040.1 - 0.2 11.4 7.3 0.03 14.1 2.0 1.8 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain PAP2 PF01569.16 GAP84041.1 - 5.2e-14 52.0 1.7 6.6e-14 51.6 0.4 1.9 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.9 GAP84041.1 - 0.0073 16.0 0.0 0.15 11.7 0.0 2.2 2 0 0 2 2 2 1 Divergent PAP2 family PrgI PF12666.2 GAP84041.1 - 2.3 8.4 7.7 0.24 11.5 0.3 2.5 3 0 0 3 3 3 0 PrgI family protein UbiA PF01040.13 GAP84041.1 - 3.6 6.7 8.1 0.68 9.1 2.3 1.9 1 1 1 2 2 2 0 UbiA prenyltransferase family DUF3402 PF11882.3 GAP84042.1 - 6.8e-150 499.6 0.0 9.5e-150 499.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 GAP84042.1 - 1.6e-65 220.8 0.0 2.3e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein GAS2 PF02187.12 GAP84043.1 - 3.8e-05 23.3 0.0 8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain PQ-loop PF04193.9 GAP84044.1 - 2.3e-32 110.3 11.2 4e-17 61.5 2.4 3.1 3 0 0 3 3 3 2 PQ loop repeat Glycophorin_A PF01102.13 GAP84044.1 - 0.18 11.5 0.1 5.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Glycophorin A Fun_ATP-synt_8 PF05933.8 GAP84044.1 - 1.2 9.2 6.5 0.14 12.2 0.7 2.3 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) GATase_4 PF13230.1 GAP84045.1 - 7.4e-18 64.1 0.0 5.7e-16 58.0 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 GAP84045.1 - 6.6e-10 39.0 0.0 1.1e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 GAP84045.1 - 5.7e-07 28.5 0.0 4.1e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II Dynamin_N PF00350.18 GAP84046.1 - 1.2e-42 145.5 0.0 2.8e-42 144.3 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 GAP84046.1 - 5.9e-10 38.3 0.1 1.6e-08 33.6 0.0 2.3 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 GAP84046.1 - 0.00056 19.8 0.0 0.0042 17.0 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 GAP84046.1 - 0.0039 17.6 0.0 0.01 16.3 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein SRI PF08236.6 GAP84046.1 - 0.0052 16.7 0.1 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain AAA_21 PF13304.1 GAP84046.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain RFC1 PF08519.7 GAP84046.1 - 0.12 12.1 0.1 2.3 7.9 0.0 2.8 3 0 0 3 3 3 0 Replication factor RFC1 C terminal domain AAA PF00004.24 GAP84049.1 - 4e-18 65.9 0.1 1.9e-17 63.7 0.0 2.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 GAP84049.1 - 0.0018 17.3 0.0 0.0031 16.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 GAP84049.1 - 0.021 14.7 0.2 0.089 12.7 0.1 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 GAP84049.1 - 0.038 14.1 0.1 0.15 12.1 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.1 GAP84049.1 - 0.071 12.8 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain KaiC PF06745.8 GAP84049.1 - 0.14 11.2 0.2 0.29 10.2 0.1 1.5 1 0 0 1 1 1 0 KaiC GSDH PF07995.6 GAP84050.1 - 1.3e-05 24.4 0.1 4e-05 22.8 0.1 1.9 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase SGL PF08450.7 GAP84050.1 - 0.005 16.2 0.0 0.014 14.8 0.0 1.8 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Orn_Arg_deC_N PF02784.11 GAP84053.1 - 2.5e-78 262.7 0.0 3.4e-78 262.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 GAP84053.1 - 1.9e-30 104.9 0.1 3.6e-30 104.0 0.1 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 GAP84053.1 - 0.0023 17.2 0.0 0.0045 16.3 0.0 1.5 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF2793 PF10983.3 GAP84054.1 - 0.022 14.5 0.1 0.039 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2793) HTH_Tnp_4 PF13613.1 GAP84054.1 - 0.054 13.0 0.0 0.099 12.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 GAP84054.1 - 0.082 12.5 0.2 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HET PF06985.6 GAP84055.1 - 3.4e-22 79.1 0.0 6.9e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ferric_reduct PF01794.14 GAP84056.1 - 2.5e-18 66.3 10.7 2.5e-18 66.3 7.4 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 GAP84056.1 - 0.052 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 FAD-binding domain M16C_assoc PF08367.6 GAP84057.1 - 2e-60 203.6 0.0 3.1e-60 203.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 GAP84057.1 - 1.6e-37 128.9 0.0 2.2e-22 79.6 0.0 3.4 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 GAP84057.1 - 2e-07 30.8 0.0 1.1e-06 28.4 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Taxilin PF09728.4 GAP84058.1 - 3.9e-83 279.0 60.5 6e-83 278.4 41.9 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein TMF_TATA_bd PF12325.3 GAP84058.1 - 0.012 15.3 14.5 0.012 15.3 10.1 4.7 2 2 1 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF1180 PF06679.7 GAP84058.1 - 0.43 10.4 5.7 0.15 11.9 1.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) Shugoshin_N PF07558.6 GAP84058.1 - 1.9 8.2 15.0 1.8 8.3 0.2 4.2 3 1 0 3 3 3 0 Shugoshin N-terminal coiled-coil region LTV PF04180.9 GAP84059.1 - 1.8e-97 327.5 16.3 2.1e-97 327.3 11.3 1.0 1 0 0 1 1 1 1 Low temperature viability protein MMR_HSR1 PF01926.18 GAP84060.1 - 8.5e-18 64.3 0.3 1.8e-15 56.8 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 GAP84060.1 - 3.3e-07 29.6 0.4 8.6e-06 25.1 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 GAP84060.1 - 0.00024 20.3 0.0 0.00045 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 GAP84060.1 - 0.0023 17.7 6.3 0.057 13.2 0.4 3.2 3 1 1 4 4 4 2 Dynamin family AIG1 PF04548.11 GAP84060.1 - 0.0027 16.8 0.0 0.0052 15.9 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 GAP84060.1 - 0.048 14.1 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Prothymosin PF03247.9 GAP84060.1 - 0.1 12.7 12.2 0.21 11.7 8.5 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family RRP7 PF12923.2 GAP84061.1 - 0.016 15.2 0.2 0.022 14.7 0.1 1.3 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) TFIIF_alpha PF05793.7 GAP84061.1 - 0.34 9.2 3.4 0.38 9.0 2.4 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HCV_NS4a PF01006.15 GAP84062.1 - 0.083 12.4 0.4 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a Aldo_ket_red PF00248.16 GAP84063.1 - 1.2e-56 191.6 0.0 1.3e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hydrolase_6 PF13344.1 GAP84064.1 - 4.5e-20 71.4 0.0 1.1e-19 70.2 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAP84064.1 - 3.7e-18 65.0 0.0 1.3e-17 63.2 0.0 2.0 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 GAP84064.1 - 0.0013 19.0 0.0 0.093 12.9 0.0 2.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAP84064.1 - 0.012 16.0 0.0 0.16 12.3 0.0 2.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Apt1 PF10351.4 GAP84064.1 - 0.25 10.1 0.0 0.25 10.1 0.0 1.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain Cerato-platanin PF07249.7 GAP84065.1 - 0.0026 17.7 0.1 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 Cerato-platanin HET PF06985.6 GAP84066.1 - 3.5e-29 101.7 0.2 6.3e-29 100.9 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_M20 PF01546.23 GAP84067.1 - 3.2e-27 95.2 0.0 5e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAP84067.1 - 1.1e-11 44.3 0.1 2.4e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 GAP84067.1 - 0.02 14.6 0.0 0.045 13.4 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M28 Abhydrolase_1 PF00561.15 GAP84069.1 - 3.6e-10 39.7 0.0 1.2e-08 34.7 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAP84069.1 - 4.4e-10 39.8 0.0 6.9e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP84069.1 - 0.027 14.2 0.1 0.94 9.2 0.1 2.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family CutC PF03932.9 GAP84070.1 - 5.1e-26 91.1 0.2 6.8e-24 84.2 0.1 3.3 1 1 0 1 1 1 1 CutC family adh_short PF00106.20 GAP84071.1 - 3.8e-08 33.4 0.1 6.1e-08 32.7 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 GAP84071.1 - 0.00041 20.4 0.0 0.00059 19.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 GAP84071.1 - 0.0007 19.4 0.0 0.00083 19.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAP84071.1 - 0.019 14.3 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 GAP84071.1 - 0.094 11.8 0.1 0.2 10.8 0.0 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PGP_phosphatase PF09419.5 GAP84072.1 - 8.2e-63 210.7 0.0 9.7e-63 210.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 GAP84072.1 - 3.1e-06 26.7 0.0 6.1e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like ORC2 PF04084.9 GAP84073.1 - 4.6e-100 334.6 0.0 5.7e-100 334.3 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 GFA PF04828.9 GAP84074.1 - 2.7e-10 40.0 0.1 2.7e-10 40.0 0.1 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-dskA_traR PF01258.12 GAP84074.1 - 0.81 9.4 4.6 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Lipase_GDSL_2 PF13472.1 GAP84076.1 - 5e-12 46.3 0.0 7.2e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAP84076.1 - 5.6e-10 39.4 0.0 1.8e-09 37.7 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 GAP84076.1 - 0.00023 20.9 0.1 0.00081 19.1 0.0 1.9 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Fasciclin PF02469.17 GAP84077.1 - 5.2e-22 78.2 0.2 2e-15 56.8 0.1 2.5 2 1 0 2 2 2 2 Fasciclin domain Imm37 PF15598.1 GAP84078.1 - 0.11 12.4 0.2 3.1 7.6 0.0 2.5 2 1 0 2 2 2 0 Immunity protein 37 Pkinase PF00069.20 GAP84079.1 - 7.5e-70 235.0 0.0 1e-69 234.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP84079.1 - 3.4e-50 170.5 0.0 5e-50 169.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP84079.1 - 2.6e-06 26.6 0.0 5.6e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Transglut_core PF01841.14 GAP84080.1 - 7.8e-10 38.9 0.9 1.6e-09 37.9 0.6 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.12 GAP84080.1 - 1.2e-08 34.2 0.2 2.6e-08 33.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAP84080.1 - 8.8e-08 31.4 1.1 2.1e-07 30.1 0.0 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 GAP84080.1 - 6.4e-05 22.4 0.1 0.00013 21.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain Astacin PF01400.19 GAP84080.1 - 0.25 10.7 0.1 0.45 9.8 0.0 1.3 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Sugar_tr PF00083.19 GAP84081.1 - 6.2e-61 206.3 4.8 7e-61 206.1 3.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP84081.1 - 8.5e-14 51.0 12.0 1e-13 50.7 8.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Homeobox PF00046.24 GAP84083.1 - 3.6e-17 61.7 4.8 8.6e-17 60.5 3.3 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 GAP84083.1 - 0.0012 18.4 0.1 0.0037 16.9 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain HCO3_cotransp PF00955.16 GAP84084.1 - 4.7e-63 213.5 9.9 7.8e-41 140.2 2.5 3.1 2 1 1 3 3 3 3 HCO3- transporter family Spt5_N PF11942.3 GAP84084.1 - 0.004 17.7 1.6 0.0071 16.9 1.1 1.4 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal CAF1A PF12253.3 GAP84084.1 - 0.027 14.5 0.3 0.054 13.6 0.2 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Peptidase_M41 PF01434.13 GAP84085.1 - 7.1e-71 238.0 0.0 1e-70 237.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 GAP84085.1 - 3.4e-42 143.7 0.0 7.7e-42 142.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 GAP84085.1 - 3.5e-12 46.4 0.0 1.3e-11 44.5 0.0 2.1 1 0 0 1 1 1 1 FtsH Extracellular AAA_22 PF13401.1 GAP84085.1 - 0.00025 21.1 0.5 0.043 13.9 0.4 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 GAP84085.1 - 0.0013 18.4 0.0 0.0046 16.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 GAP84085.1 - 0.0014 18.5 0.0 0.031 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 GAP84085.1 - 0.0037 18.0 0.0 0.014 16.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 GAP84085.1 - 0.0041 16.5 1.0 0.1 11.9 0.2 3.2 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.7 GAP84085.1 - 0.0048 15.9 0.1 0.019 13.9 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 GAP84085.1 - 0.01 14.5 0.1 0.019 13.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus IstB_IS21 PF01695.12 GAP84085.1 - 0.011 15.1 0.0 0.026 13.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.1 GAP84085.1 - 0.017 15.0 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 GAP84085.1 - 0.043 13.7 0.5 0.67 9.9 0.1 2.7 2 1 1 3 3 3 0 AAA ATPase domain Zeta_toxin PF06414.7 GAP84085.1 - 0.044 12.8 0.1 0.14 11.1 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 GAP84085.1 - 0.045 13.5 1.5 0.14 11.9 0.4 2.3 3 0 0 3 3 2 0 Part of AAA domain AAA_14 PF13173.1 GAP84085.1 - 0.067 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 GAP84085.1 - 0.14 11.3 0.2 0.28 10.3 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Fungal_trans PF04082.13 GAP84086.1 - 1.7e-28 99.1 0.0 3e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP84086.1 - 1.3e-08 34.5 8.3 2.3e-08 33.7 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain efThoc1 PF11957.3 GAP84086.1 - 0.049 12.1 0.1 0.13 10.7 0.0 1.6 2 0 0 2 2 2 0 THO complex subunit 1 transcription elongation factor Syndecan PF01034.15 GAP84087.1 - 0.022 14.4 0.1 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Skp1 PF01466.14 GAP84088.1 - 0.38 10.7 3.4 0.83 9.7 2.3 1.6 1 0 0 1 1 1 0 Skp1 family, dimerisation domain DUF1666 PF07891.7 GAP84088.1 - 2.5 7.4 9.4 0.22 10.9 3.4 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1666) RR_TM4-6 PF06459.7 GAP84088.1 - 3.6 7.4 11.2 4.4 7.1 7.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 IGPD PF00475.13 GAP84089.1 - 2.9e-61 205.5 0.4 4.2e-61 205.0 0.3 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase MARVEL PF01284.18 GAP84090.1 - 0.00056 19.7 15.3 0.00099 18.9 10.6 1.4 1 0 0 1 1 1 1 Membrane-associating domain DUF4233 PF14017.1 GAP84090.1 - 0.78 9.6 5.9 2.7 7.9 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) CENP-S PF15630.1 GAP84091.1 - 4.7e-35 119.6 0.0 7.5e-35 118.9 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TFIID-18kDa PF02269.11 GAP84091.1 - 0.0085 15.8 0.1 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 GAP84091.1 - 0.0085 16.1 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T PF15511.1 GAP84091.1 - 0.0087 15.3 0.0 0.0095 15.2 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 GAP84091.1 - 0.0089 15.7 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF PF02969.12 GAP84091.1 - 0.024 14.5 0.1 0.41 10.6 0.0 2.5 3 0 0 3 3 3 0 TATA box binding protein associated factor (TAF) PGA2 PF07543.7 GAP84092.1 - 1.2e-36 125.5 4.6 1.4e-36 125.3 3.2 1.1 1 0 0 1 1 1 1 Protein trafficking PGA2 INCENP_ARK-bind PF03941.10 GAP84092.1 - 1.5 8.7 6.0 10 6.0 0.1 2.4 1 1 1 2 2 2 0 Inner centromere protein, ARK binding region Drc1-Sld2 PF11719.3 GAP84092.1 - 1.6 7.7 8.1 2 7.3 5.6 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein AA_permease_2 PF13520.1 GAP84093.1 - 4.8e-45 153.8 30.8 6e-45 153.5 21.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAP84093.1 - 7.7e-26 90.4 31.9 1.8e-25 89.2 22.1 1.5 1 1 0 1 1 1 1 Amino acid permease Glyco_hydro_28 PF00295.12 GAP84095.1 - 3.4e-44 151.1 9.6 4.5e-44 150.7 6.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 GAP84095.1 - 5.5 6.7 27.4 6.7e+02 -0.1 19.0 2.5 1 1 0 1 1 1 0 Right handed beta helix region Malic_M PF03949.10 GAP84096.1 - 4.4e-85 285.3 0.0 6.3e-85 284.7 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 GAP84096.1 - 3.8e-69 231.8 0.0 6e-69 231.2 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Epimerase PF01370.16 GAP84098.1 - 1.2e-11 44.4 0.0 2.7e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAP84098.1 - 4.9e-06 26.6 0.0 1.3e-05 25.2 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding Semialdhyde_dh PF01118.19 GAP84098.1 - 1.2e-05 25.6 0.0 3.7e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 GAP84098.1 - 3.9e-05 22.7 0.0 5.5e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 GAP84098.1 - 5.3e-05 22.0 0.0 0.003 16.2 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 GAP84098.1 - 0.00028 20.2 0.0 0.0004 19.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 GAP84098.1 - 0.0016 17.3 0.0 0.0024 16.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 GAP84098.1 - 0.0019 17.1 0.0 0.0086 15.0 0.0 2.1 2 1 0 2 2 2 1 Male sterility protein Shikimate_DH PF01488.15 GAP84098.1 - 0.0035 17.4 0.0 0.0054 16.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.15 GAP84098.1 - 0.02 14.7 0.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.18 GAP84098.1 - 0.13 12.1 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DUF4066 PF13278.1 GAP84099.1 - 2.2e-14 53.0 0.1 2.9e-14 52.6 0.1 1.3 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 GAP84099.1 - 0.0006 19.2 0.1 0.00091 18.7 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family FAD_binding_4 PF01565.18 GAP84100.1 - 6.9e-21 74.1 1.3 9.4e-21 73.7 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain Mito_carr PF00153.22 GAP84101.1 - 1.2e-60 201.2 5.1 4.3e-21 74.4 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PG_binding_1 PF01471.13 GAP84101.1 - 0.025 14.5 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative peptidoglycan binding domain NIF PF03031.13 GAP84102.1 - 7.4e-18 64.7 0.0 1.3e-17 63.8 0.0 1.4 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase DUF947 PF06102.7 GAP84103.1 - 5.6e-50 169.4 10.4 9.1e-50 168.7 7.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF947) DNA_pol_phi PF04931.8 GAP84103.1 - 7.4 4.2 18.6 9.9 3.7 12.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi ABC1 PF03109.11 GAP84104.1 - 2.2e-30 105.0 0.0 4.2e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 ABC1 family WD40 PF00400.27 GAP84105.1 - 2.7e-73 239.4 25.3 2.1e-09 36.8 0.0 12.0 11 1 0 11 11 11 11 WD domain, G-beta repeat Utp13 PF08625.6 GAP84105.1 - 3e-41 140.3 0.1 4.5e-41 139.8 0.1 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 GAP84105.1 - 1.4e-09 36.6 6.4 0.028 12.5 0.0 5.5 2 2 2 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAP84105.1 - 1.2e-06 27.5 9.1 0.13 10.9 0.0 6.0 4 2 0 5 5 5 4 Nup133 N terminal like CHB_HEX_C PF03174.8 GAP84107.1 - 0.0035 17.1 0.3 0.011 15.5 0.2 1.9 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain CHB_HEX_C_1 PF13290.1 GAP84107.1 - 0.042 13.6 0.5 0.042 13.6 0.3 1.9 2 0 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain adh_short PF00106.20 GAP84108.1 - 5.3e-18 65.4 0.5 1.9e-17 63.7 0.3 1.9 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 GAP84108.1 - 1.7e-08 34.3 0.0 5.3e-08 32.7 0.1 1.7 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 GAP84108.1 - 1.2e-07 31.9 0.9 3.6e-07 30.3 0.4 1.8 2 0 0 2 2 2 1 NADH(P)-binding adh_short_C2 PF13561.1 GAP84108.1 - 1.8e-07 31.2 0.0 2.6e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAP84108.1 - 0.0052 16.2 0.0 0.007 15.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAP84108.1 - 0.098 12.4 0.4 0.3 10.9 0.3 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF4556 PF15094.1 GAP84108.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4556) Oxidored_FMN PF00724.15 GAP84109.1 - 4.4e-24 85.0 0.0 4e-20 72.0 0.0 2.2 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family DUF561 PF04481.7 GAP84109.1 - 0.015 14.2 0.0 0.021 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF561) Abhydrolase_6 PF12697.2 GAP84110.1 - 2.8e-34 118.9 12.9 5.8e-34 117.9 8.9 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP84110.1 - 8.6e-17 61.4 0.0 1.3e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP84110.1 - 5.8e-15 55.3 0.9 4.6e-14 52.4 0.7 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAP84110.1 - 6.4e-05 22.7 0.2 0.00013 21.7 0.1 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 GAP84110.1 - 0.00012 20.6 0.0 0.00018 20.1 0.0 1.2 1 0 0 1 1 1 1 Ndr family Mito_carr PF00153.22 GAP84111.1 - 6.4e-74 243.7 1.5 6.2e-26 89.9 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 GAP84111.1 - 1.1e-18 65.0 3.7 3.1e-06 26.0 0.0 5.9 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.1 GAP84111.1 - 2.2e-18 66.1 3.8 2.8e-07 30.5 0.1 4.7 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 GAP84111.1 - 1.2e-16 58.9 3.1 4.5e-05 22.9 0.0 6.3 7 0 0 7 7 7 3 EF-hand domain EF-hand_5 PF13202.1 GAP84111.1 - 2.6e-11 42.2 1.4 0.00099 18.3 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 GAP84111.1 - 2.8e-11 42.8 2.8 0.00036 20.0 0.1 5.4 4 2 1 5 5 5 4 EF-hand domain pair EF-hand_9 PF14658.1 GAP84111.1 - 0.1 12.5 0.0 41 4.1 0.0 3.9 4 0 0 4 4 4 0 EF-hand domain Cyclin_N PF00134.18 GAP84112.1 - 4.1e-43 145.9 0.0 7.4e-43 145.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 GAP84112.1 - 1.6e-32 111.9 0.1 3.5e-32 110.7 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF433 PF04255.9 GAP84112.1 - 0.14 11.6 0.1 0.4 10.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Zn_clus PF00172.13 GAP84114.1 - 0.00052 19.8 11.7 0.00097 18.9 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 GAP84114.1 - 0.077 12.2 0.1 0.077 12.2 0.1 2.7 3 0 0 3 3 3 0 Histone chaperone domain CHZ MFS_1 PF07690.11 GAP84115.1 - 5.8e-25 87.7 22.5 8e-25 87.2 15.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2427 PF10348.4 GAP84115.1 - 0.24 10.9 3.3 1.7 8.2 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) Abhydrolase_3 PF07859.8 GAP84116.1 - 9.5e-06 25.3 3.0 0.00026 20.6 0.2 3.2 3 1 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAP84116.1 - 1.4e-05 25.0 1.6 2e-05 24.5 1.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP84116.1 - 0.00068 19.4 1.6 0.0012 18.6 1.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 GAP84116.1 - 0.0027 17.9 0.1 0.0053 17.0 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain DUF3089 PF11288.3 GAP84116.1 - 0.089 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Abhydrolase_1 PF00561.15 GAP84116.1 - 0.089 12.3 0.0 0.25 10.8 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 GAP84116.1 - 0.12 11.9 0.1 0.17 11.5 0.0 1.4 1 1 0 1 1 1 0 Lipase (class 3) RNA_pol_Rpc4 PF05132.9 GAP84117.1 - 1.7e-20 73.3 0.0 1.7e-20 73.3 0.0 3.2 4 0 0 4 4 4 1 RNA polymerase III RPC4 UreD PF01774.12 GAP84118.1 - 6.7e-56 189.0 0.0 8.1e-56 188.8 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein STAG PF08514.6 GAP84119.1 - 7.5e-27 93.3 0.3 2.5e-26 91.6 0.0 2.1 2 0 0 2 2 2 1 STAG domain HEAT_2 PF13646.1 GAP84119.1 - 2.5e-05 24.4 0.0 0.00069 19.8 0.0 2.8 1 1 1 2 2 2 2 HEAT repeats Cnd1 PF12717.2 GAP84119.1 - 0.0072 16.1 0.4 0.051 13.4 0.1 2.6 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 GAP84119.1 - 0.036 13.4 0.1 0.2 10.9 0.0 2.2 3 0 0 3 3 3 0 CLASP N terminal HEAT PF02985.17 GAP84119.1 - 0.038 14.0 2.4 24 5.3 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat POT1 PF02765.12 GAP84120.1 - 9.4e-12 45.0 0.0 2e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Arm PF00514.18 GAP84121.1 - 3.3e-93 302.6 14.1 1.5e-13 49.9 0.0 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 GAP84121.1 - 2.1e-24 85.5 0.4 4.6e-10 39.6 0.0 5.7 1 1 3 5 5 5 5 HEAT repeats IBB PF01749.15 GAP84121.1 - 2.6e-23 82.0 0.8 4.7e-23 81.1 0.6 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 GAP84121.1 - 2.9e-21 75.3 12.3 7.3e-10 39.0 0.1 6.3 5 1 2 7 7 7 3 HEAT-like repeat HEAT PF02985.17 GAP84121.1 - 9e-20 68.9 2.2 4.7e-06 26.2 0.0 7.2 7 0 0 7 7 7 4 HEAT repeat Arm_2 PF04826.8 GAP84121.1 - 1.7e-09 37.1 0.0 0.0024 17.0 0.0 4.0 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 GAP84121.1 - 1.2e-05 23.8 0.0 0.0011 17.4 0.0 2.9 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 GAP84121.1 - 0.00052 19.9 0.0 1.1 9.1 0.0 4.3 2 1 4 6 6 6 1 V-ATPase subunit H HEAT_PBS PF03130.11 GAP84121.1 - 0.00071 19.8 0.5 1.6 9.4 0.0 4.4 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 GAP84121.1 - 0.00072 17.9 0.8 0.11 10.8 0.0 3.0 3 1 0 3 3 3 1 Proteasome non-ATPase 26S subunit SURF6 PF04935.7 GAP84121.1 - 2.6 7.3 7.7 3.9 6.7 5.4 1.2 1 0 0 1 1 1 0 Surfeit locus protein 6 6PF2K PF01591.13 GAP84122.1 - 3.5e-61 206.1 0.1 4.7e-61 205.6 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 GAP84122.1 - 7e-19 68.4 0.8 1.2e-18 67.7 0.5 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 GAP84122.1 - 0.00041 20.2 0.1 0.0019 18.0 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAP84122.1 - 0.0017 19.1 0.9 0.44 11.3 0.0 3.1 2 1 1 3 3 3 1 AAA domain Porin_3 PF01459.17 GAP84123.1 - 7e-78 261.6 0.4 8.1e-78 261.4 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin SPC22 PF04573.7 GAP84124.1 - 2.7e-08 33.2 0.8 1.5e-07 30.8 0.0 1.9 1 1 1 2 2 2 1 Signal peptidase subunit IL17_R_N PF15037.1 GAP84124.1 - 0.063 12.2 0.0 0.068 12.1 0.0 1.0 1 0 0 1 1 1 0 Interleukin-17 receptor extracellular region Peptidase_C48 PF02902.14 GAP84125.1 - 2.6e-33 115.4 0.0 7.5e-33 113.9 0.0 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain WSC PF01822.14 GAP84127.1 - 6.6e-73 240.6 56.6 1e-19 70.2 4.1 4.5 4 0 0 4 4 4 4 WSC domain peroxidase PF00141.18 GAP84127.1 - 1.3e-20 73.9 0.0 2.4e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 Peroxidase SUI1 PF01253.17 GAP84128.1 - 2.4e-28 97.7 1.8 3e-28 97.4 1.3 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Ribosomal_L4 PF00573.17 GAP84129.1 - 7.7e-41 139.5 0.2 1e-40 139.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 GAP84129.1 - 5.5e-25 87.0 1.8 1e-24 86.2 0.1 2.0 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Aminotran_1_2 PF00155.16 GAP84130.1 - 3.4e-07 29.5 0.0 6.5e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II MTHFR PF02219.12 GAP84133.1 - 4.9e-102 340.8 0.0 7.1e-102 340.3 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase HTH_WhiA PF02650.9 GAP84134.1 - 4.9e-06 26.8 0.1 0.0029 17.9 0.0 2.8 3 0 0 3 3 3 2 WhiA C-terminal HTH domain PQ-loop PF04193.9 GAP84135.1 - 1.5e-18 66.0 2.6 2e-12 46.4 0.3 2.6 2 0 0 2 2 2 2 PQ loop repeat Zn_clus PF00172.13 GAP84136.1 - 4.9e-07 29.5 8.3 8e-07 28.8 5.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cohesin_load PF10345.4 GAP84138.1 - 7.6e-127 424.0 11.8 7.6e-127 424.0 8.2 1.5 2 0 0 2 2 2 1 Cohesin loading factor Ycf1 PF05758.7 GAP84138.1 - 0.23 9.1 9.2 0.037 11.7 3.5 1.7 2 0 0 2 2 2 0 Ycf1 Gti1_Pac2 PF09729.4 GAP84138.1 - 0.84 9.4 6.5 1.7 8.4 4.5 1.6 1 0 0 1 1 1 0 Gti1/Pac2 family Abhydrolase_1 PF00561.15 GAP84140.1 - 2.3e-10 40.4 0.0 3.5e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAP84140.1 - 2.4e-09 37.4 0.0 9.4e-09 35.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP84140.1 - 1.5e-05 24.7 0.0 0.00019 21.1 0.0 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family Cutinase PF01083.17 GAP84140.1 - 0.0011 18.7 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 Cutinase RAI1 PF08652.6 GAP84141.1 - 7.7e-29 99.2 0.0 1.6e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease DUF410 PF04190.8 GAP84143.1 - 4.3e-51 173.9 0.0 5.1e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) EHN PF06441.7 GAP84145.1 - 1.6e-17 63.3 0.0 3.3e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 GAP84145.1 - 0.00061 19.7 0.1 0.0011 18.9 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family ELO PF01151.13 GAP84146.1 - 1e-63 214.9 20.0 1.4e-63 214.5 13.9 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family adh_short PF00106.20 GAP84148.1 - 2.9e-07 30.5 2.9 2.8e-06 27.3 2.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 GAP84148.1 - 0.0002 21.0 0.4 0.00039 20.1 0.3 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.1 GAP84148.1 - 0.025 14.3 0.0 0.052 13.3 0.0 1.5 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase FAD_oxidored PF12831.2 GAP84148.1 - 0.076 12.0 0.1 0.094 11.7 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_10 PF13460.1 GAP84148.1 - 0.082 12.9 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding KR PF08659.5 GAP84148.1 - 0.23 11.1 2.6 0.34 10.5 0.9 2.0 2 1 0 2 2 2 0 KR domain COX5A PF02284.11 GAP84149.1 - 2.1e-41 140.2 0.6 2.5e-41 139.9 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va HDA2-3 PF11496.3 GAP84150.1 - 1.4e-11 43.7 1.5 1.2e-10 40.7 1.0 2.2 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Myosin_tail_1 PF01576.14 GAP84150.1 - 0.011 13.4 23.9 0.14 9.8 11.0 2.1 1 1 0 2 2 2 0 Myosin tail Chromo PF00385.19 GAP84151.1 - 0.00023 20.7 0.1 0.00038 20.0 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Trypan_PARP PF05887.6 GAP84151.1 - 0.00057 19.7 5.1 0.00057 19.7 3.5 2.0 2 1 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.8 GAP84151.1 - 0.0039 15.6 10.3 0.0053 15.1 7.1 1.2 1 0 0 1 1 1 1 Neisseria meningitidis TspB protein GMC_oxred_C PF05199.8 GAP84152.1 - 4.3e-10 40.0 0.0 1.7e-07 31.6 0.0 2.8 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.14 GAP84152.1 - 1.8e-08 33.9 0.0 9.6e-08 31.5 0.0 2.1 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAP84152.1 - 5.8e-05 22.1 0.1 9.7e-05 21.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAP84152.1 - 0.00011 22.1 0.3 0.00035 20.5 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 GAP84152.1 - 0.00054 19.1 0.1 0.00098 18.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 GAP84152.1 - 0.0044 15.9 0.2 0.014 14.3 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAP84152.1 - 0.0056 16.5 0.0 0.037 13.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAP84152.1 - 0.0075 15.1 0.1 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 GAP84152.1 - 0.042 12.3 0.0 0.066 11.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 GAP84152.1 - 0.046 12.7 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 GAP84152.1 - 0.092 13.1 0.0 0.092 13.1 0.0 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 GAP84152.1 - 0.17 10.2 0.0 0.25 9.6 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Lycopene_cycl PF05834.7 GAP84152.1 - 0.21 10.4 0.0 0.34 9.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein ELFV_dehydrog PF00208.16 GAP84154.1 - 1.2e-81 273.8 3.8 1.5e-81 273.5 2.6 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 GAP84154.1 - 6e-47 158.4 0.0 1.1e-46 157.6 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 GAP84154.1 - 0.0057 16.8 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding DNA_pol_B PF00136.16 GAP84155.1 - 1.1e-144 482.7 3.2 1.6e-144 482.1 2.2 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 GAP84155.1 - 1.4e-79 267.3 0.0 8.1e-79 264.8 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 GAP84155.1 - 2.4e-23 81.9 4.2 5e-23 80.8 2.9 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 GAP84155.1 - 4e-05 23.4 0.2 0.00022 21.0 0.1 2.3 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_2 PF03175.8 GAP84155.1 - 0.023 13.3 4.2 0.8 8.3 0.7 2.9 2 1 0 2 2 2 0 DNA polymerase type B, organellar and viral C1_1 PF00130.17 GAP84155.1 - 0.33 10.7 9.4 0.14 11.9 0.5 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Peptidase_M48 PF01435.13 GAP84156.1 - 2.6e-52 177.6 0.2 3.7e-52 177.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 GAP84156.1 - 0.0001 21.4 0.1 0.00017 20.7 0.1 1.4 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF2201_N PF13203.1 GAP84156.1 - 0.066 12.3 1.4 0.073 12.2 0.2 1.5 2 0 0 2 2 2 0 Putative metallopeptidase domain SprT-like PF10263.4 GAP84156.1 - 0.11 12.1 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 SprT-like family DUF4538 PF15061.1 GAP84156.1 - 1 8.7 3.9 0.32 10.3 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Ish1 PF10281.4 GAP84157.1 - 0.00013 21.9 0.2 0.00034 20.6 0.2 1.7 1 1 0 1 1 1 1 Putative stress-responsive nuclear envelope protein SAP PF02037.22 GAP84157.1 - 0.0047 16.3 0.1 0.0095 15.4 0.1 1.5 1 1 0 1 1 1 1 SAP domain HeH PF12949.2 GAP84157.1 - 0.054 13.0 0.0 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 HeH/LEM domain Ribosomal_L38e PF01781.13 GAP84158.1 - 1e-31 108.4 3.9 1.3e-31 108.1 2.7 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family DUF1395 PF07160.7 GAP84158.1 - 0.055 12.9 0.5 0.061 12.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) ABM PF03992.11 GAP84159.1 - 5.7e-05 23.0 8.7 0.016 15.2 3.5 3.4 2 2 0 2 2 2 2 Antibiotic biosynthesis monooxygenase GHMP_kinases_N PF00288.21 GAP84160.1 - 1.1e-19 70.2 0.0 1.1e-19 70.2 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 GAP84160.1 - 5.7e-07 29.6 0.1 1.3e-06 28.5 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GvpG PF05120.7 GAP84160.1 - 0.039 13.7 0.1 0.084 12.6 0.1 1.5 1 0 0 1 1 1 0 Gas vesicle protein G WW PF00397.21 GAP84160.1 - 0.072 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 WW domain GalKase_gal_bdg PF10509.4 GAP84160.1 - 0.12 11.6 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Galactokinase galactose-binding signature PPTA PF01239.17 GAP84161.1 - 1.5e-38 128.5 13.9 1.9e-07 30.1 0.1 5.9 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_7 PF13176.1 GAP84161.1 - 0.021 14.5 1.5 0.48 10.3 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAP84161.1 - 0.041 13.6 1.1 0.75 9.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAP84161.1 - 0.061 13.2 1.0 6.2 6.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF572 PF04502.8 GAP84162.1 - 4.4e-76 256.1 4.4 5.1e-76 255.9 3.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-dskA_traR PF01258.12 GAP84162.1 - 0.055 13.2 0.1 0.29 10.9 0.1 2.2 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger IBR PF01485.16 GAP84162.1 - 0.056 13.3 0.5 0.11 12.3 0.3 1.5 1 0 0 1 1 1 0 IBR domain Benyvirus_14KDa PF07255.6 GAP84162.1 - 0.17 11.7 0.6 0.75 9.6 0.5 1.8 1 1 0 1 1 1 0 Benyvirus 14KDa protein Phage_B PF02304.10 GAP84162.1 - 7.5 6.8 9.6 3.9 7.7 0.5 2.4 1 1 1 2 2 2 0 Scaffold protein B Spc97_Spc98 PF04130.8 GAP84163.1 - 1.2e-68 231.7 5.6 1.2e-68 231.7 3.9 1.4 2 0 0 2 2 2 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 GAP84163.1 - 5.2e-08 31.5 0.0 8.2e-08 30.8 0.0 1.2 1 0 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 TilS PF09179.6 GAP84163.1 - 0.017 15.1 0.3 0.088 12.8 0.2 2.3 1 0 0 1 1 1 0 TilS substrate binding domain EntA_Immun PF08951.5 GAP84163.1 - 0.056 13.5 0.1 0.39 10.9 0.1 2.4 2 0 0 2 2 2 0 Enterocin A Immunity Glyco_transf_15 PF01793.11 GAP84164.1 - 1.1e-134 448.5 6.6 1.4e-134 448.2 4.6 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase WD40 PF00400.27 GAP84165.1 - 1.9e-25 87.7 5.2 5.6e-07 29.1 0.1 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 GAP84165.1 - 0.042 12.1 0.1 0.15 10.2 0.1 1.8 2 0 0 2 2 2 0 Cytochrome D1 heme domain PQQ_3 PF13570.1 GAP84165.1 - 5.9 7.3 12.6 3.3 8.1 0.5 4.6 4 1 1 5 5 5 0 PQQ-like domain Pet127 PF08634.5 GAP84166.1 - 4.5e-121 403.2 3.6 6.7e-121 402.6 2.5 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Serglycin PF04360.7 GAP84167.1 - 0.0013 18.5 5.8 0.0099 15.6 0.6 2.2 2 0 0 2 2 2 2 Serglycin Pkinase PF00069.20 GAP84168.1 - 5.3e-75 251.9 0.0 2.2e-36 125.3 0.0 4.5 5 1 0 5 5 5 3 Protein kinase domain HGTP_anticodon2 PF12745.2 GAP84168.1 - 2e-67 227.2 0.0 2e-67 227.2 0.0 2.3 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.12 GAP84168.1 - 1.6e-44 151.9 0.0 3.9e-17 62.1 0.0 3.7 4 0 0 4 4 4 3 Protein tyrosine kinase tRNA-synt_His PF13393.1 GAP84168.1 - 2.5e-15 56.3 0.0 7.7e-15 54.7 0.0 1.8 1 0 0 1 1 1 1 Histidyl-tRNA synthetase RWD PF05773.17 GAP84168.1 - 4.6e-12 45.8 0.1 1.4e-11 44.2 0.0 1.9 1 0 0 1 1 1 1 RWD domain APH PF01636.18 GAP84168.1 - 0.0001 22.0 7.0 0.067 12.9 0.0 3.1 3 0 0 3 3 3 2 Phosphotransferase enzyme family HGTP_anticodon PF03129.15 GAP84168.1 - 0.0067 16.3 0.0 0.018 15.0 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain Pox_ser-thr_kin PF05445.6 GAP84168.1 - 0.33 9.6 0.1 13 4.4 0.0 2.2 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Cut12 PF11500.3 GAP84169.1 - 1.6e-34 118.7 16.7 1.6e-34 118.7 11.6 4.3 3 1 1 4 4 4 1 Spindle pole body formation-associated protein UreF PF01730.11 GAP84169.1 - 1.2e-08 35.2 0.2 1.2e-08 35.2 0.1 2.5 3 0 0 3 3 3 1 UreF Pox_A_type_inc PF04508.7 GAP84169.1 - 0.19 11.6 28.1 3.5 7.6 0.2 7.3 5 1 2 7 7 7 0 Viral A-type inclusion protein repeat IncA PF04156.9 GAP84169.1 - 0.61 9.6 41.2 6.6 6.2 13.3 3.5 1 1 1 2 2 2 0 IncA protein Bacillus_HBL PF05791.6 GAP84169.1 - 0.65 9.3 17.8 0.27 10.5 2.9 3.2 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) RRM_1 PF00076.17 GAP84170.1 - 9.9e-08 31.5 0.0 1.7e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP84170.1 - 1.3e-06 28.1 0.0 2.7e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP84170.1 - 3.6e-05 23.6 0.0 7.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAP84170.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 GAP84170.1 - 0.014 15.0 0.7 0.03 14.0 0.5 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Acyl-CoA_dh_1 PF00441.19 GAP84171.1 - 6.2e-30 104.2 0.4 1.2e-29 103.3 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 GAP84171.1 - 1.9e-15 56.0 0.0 4.3e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 GAP84171.1 - 1.5e-14 54.3 1.1 2.7e-14 53.5 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAP84171.1 - 2.1e-11 44.3 0.1 4.3e-11 43.3 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Spo12 PF05032.7 GAP84172.1 - 1.9e-15 56.1 0.3 3.7e-15 55.2 0.2 1.5 1 0 0 1 1 1 1 Spo12 family TGS PF02824.16 GAP84173.1 - 2.4e-19 68.8 0.1 4.5e-19 68.0 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 GAP84173.1 - 7.4e-19 67.8 0.0 1.4e-18 66.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAP84173.1 - 1.1e-12 47.5 0.0 1.6e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 GAP84173.1 - 7e-05 22.7 0.3 0.062 13.1 0.0 2.5 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 GAP84173.1 - 0.015 15.8 0.0 0.039 14.4 0.0 1.7 1 1 0 1 1 1 0 Miro-like protein ArgK PF03308.11 GAP84173.1 - 0.049 12.4 0.1 0.11 11.1 0.1 1.6 1 0 0 1 1 1 0 ArgK protein MCM PF00493.18 GAP84173.1 - 0.07 11.9 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family AAA_22 PF13401.1 GAP84173.1 - 0.095 12.8 0.1 0.79 9.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain TPR_12 PF13424.1 GAP84174.1 - 2.2e-27 94.7 22.4 1.5e-11 44.0 0.2 7.3 7 1 1 8 8 8 4 Tetratricopeptide repeat NB-ARC PF00931.17 GAP84174.1 - 7.3e-20 70.9 0.0 1.2e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.1 GAP84174.1 - 6.5e-19 67.2 18.4 2.2e-05 24.2 0.0 9.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.1 GAP84174.1 - 5.8e-12 45.0 5.2 1.2e-05 24.8 0.2 5.6 3 1 2 5 5 5 4 TPR repeat TPR_1 PF00515.23 GAP84174.1 - 3.5e-10 39.0 3.5 0.02 14.4 0.0 6.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAP84174.1 - 1.8e-09 36.7 8.3 1.8 8.6 0.0 8.5 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAP84174.1 - 3.9e-08 32.5 6.9 0.34 10.8 0.0 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAP84174.1 - 4e-08 33.2 11.4 0.25 12.1 0.0 8.4 6 2 1 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAP84174.1 - 2.1e-07 30.1 5.0 0.59 10.0 0.1 6.1 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAP84174.1 - 5.8e-06 26.8 10.1 0.93 10.2 0.2 6.1 4 2 1 5 5 4 2 Tetratricopeptide repeat AAA_16 PF13191.1 GAP84174.1 - 1.4e-05 25.1 0.4 6.9e-05 22.9 0.0 2.5 3 0 0 3 3 2 1 AAA ATPase domain TPR_19 PF14559.1 GAP84174.1 - 2.6e-05 24.4 7.3 0.12 12.7 0.0 5.7 5 1 1 6 6 5 1 Tetratricopeptide repeat Apc3 PF12895.2 GAP84174.1 - 4.2e-05 23.5 1.8 0.22 11.6 0.1 3.7 4 0 0 4 4 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 GAP84174.1 - 5.1e-05 23.4 3.0 20 5.8 0.0 6.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 GAP84174.1 - 0.0002 21.4 0.4 2.2 8.9 0.0 4.6 5 0 0 5 5 3 1 Tetratricopeptide repeat AAA_22 PF13401.1 GAP84174.1 - 0.0004 20.5 0.0 0.0016 18.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain TPR_17 PF13431.1 GAP84174.1 - 0.0025 17.8 0.4 11 6.5 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.15 GAP84174.1 - 0.017 15.0 0.2 4.3 7.5 0.0 3.8 5 0 0 5 5 2 0 PPR repeat PPR_3 PF13812.1 GAP84174.1 - 0.017 15.3 0.1 10 6.7 0.0 3.8 3 0 0 3 3 3 0 Pentatricopeptide repeat domain KaiC PF06745.8 GAP84174.1 - 0.13 11.3 0.0 0.28 10.2 0.0 1.5 1 0 0 1 1 1 0 KaiC ArsA_ATPase PF02374.10 GAP84174.1 - 0.16 10.9 0.0 0.34 9.8 0.0 1.5 1 0 0 1 1 1 0 Anion-transporting ATPase Peptidase_M49 PF03571.10 GAP84176.1 - 1.7e-188 627.1 0.0 2e-188 626.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 GFO_IDH_MocA PF01408.17 GAP84177.1 - 2.3e-11 44.2 0.6 9.7e-11 42.2 0.4 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DHDPS PF00701.17 GAP84178.1 - 3.5e-32 111.1 0.0 4e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DAO PF01266.19 GAP84179.1 - 4.9e-54 183.6 5.0 1.1e-53 182.4 3.4 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAP84179.1 - 0.00024 21.0 0.7 0.00071 19.5 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAP84179.1 - 0.00097 19.4 0.1 0.037 14.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAP84179.1 - 0.0023 16.6 1.0 0.0033 16.1 0.3 1.5 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 GAP84179.1 - 0.013 15.3 1.0 1.2 8.9 0.2 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Spermine_synth PF01564.12 GAP84179.1 - 0.056 12.3 0.0 1.9 7.3 0.0 2.1 2 0 0 2 2 2 0 Spermine/spermidine synthase NAD_binding_9 PF13454.1 GAP84179.1 - 0.057 13.1 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Saccharop_dh PF03435.13 GAP84179.1 - 0.081 11.8 0.1 0.15 10.9 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase GSHPx PF00255.14 GAP84180.1 - 3.6e-38 129.2 0.0 4.5e-38 128.9 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 GAP84180.1 - 0.00013 21.6 0.2 0.0003 20.4 0.1 1.8 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 GAP84180.1 - 0.0025 17.3 0.2 0.0036 16.8 0.1 1.4 1 1 0 1 1 1 1 Redoxin DUF4174 PF13778.1 GAP84180.1 - 0.0037 17.3 0.0 0.0058 16.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) Fungal_trans_2 PF11951.3 GAP84183.1 - 3.6e-52 177.2 0.5 6.9e-52 176.3 0.3 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Nop16 PF09420.5 GAP84184.1 - 1.5e-49 168.2 0.1 1.7e-49 168.0 0.1 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 MARVEL PF01284.18 GAP84185.1 - 2.4e-07 30.6 7.0 4.1e-07 29.9 4.9 1.4 1 0 0 1 1 1 1 Membrane-associating domain DUF4281 PF14108.1 GAP84185.1 - 0.014 15.4 0.6 0.024 14.7 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4281) MKT1_C PF12246.3 GAP84186.1 - 1.3e-63 214.2 0.0 1.8e-63 213.7 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 GAP84186.1 - 1.8e-26 92.2 0.1 3.8e-26 91.2 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 GAP84186.1 - 0.0007 19.8 0.0 0.012 15.8 0.0 2.4 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 GAP84186.1 - 0.025 14.6 0.0 0.051 13.6 0.0 1.6 1 0 0 1 1 1 0 XPG I-region DIOX_N PF14226.1 GAP84187.1 - 4.9e-21 75.4 0.0 7.9e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAP84187.1 - 9.6e-14 51.4 0.0 1.7e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3449 PF11931.3 GAP84188.1 - 2.7 7.4 15.3 0.52 9.7 2.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) Zn_clus PF00172.13 GAP84190.1 - 4.4e-09 36.1 11.1 8.6e-09 35.1 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAP84190.1 - 2.5e-05 23.0 0.1 0.00012 20.8 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 GAP84191.1 - 5.3e-16 58.2 1.5 8.4e-16 57.6 1.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP84191.1 - 2.3e-07 30.6 9.8 4.4e-07 29.7 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.8 GAP84192.1 - 3.1e-76 255.7 0.0 3.8e-76 255.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAP84192.1 - 0.004 17.1 0.4 0.15 12.0 0.3 2.2 1 1 0 1 1 1 1 NADH(P)-binding DUF2498 PF10692.4 GAP84192.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2498) DNA_pol_E_B PF04042.11 GAP84194.1 - 2.2e-53 180.6 0.0 2.9e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B WD40 PF00400.27 GAP84195.1 - 2.1e-27 93.9 15.2 1.4e-07 31.1 0.1 6.3 6 1 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.7 GAP84195.1 - 4.9e-19 68.1 0.2 7.7e-19 67.4 0.1 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 GAP84195.1 - 0.067 11.3 2.1 5.7 4.9 0.0 3.1 1 1 1 3 3 3 0 Nucleoporin Nup120/160 DNA_pol_A_exo1 PF01612.15 GAP84196.1 - 6.7e-13 48.4 0.0 1.1e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease RNA_pol_L_2 PF13656.1 GAP84197.1 - 2.8e-19 68.3 0.0 3.6e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 GAP84197.1 - 4.3e-05 22.5 0.0 7.6e-05 21.7 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain GntR PF00392.16 GAP84197.1 - 0.13 11.6 0.0 0.34 10.3 0.0 1.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Aa_trans PF01490.13 GAP84198.1 - 3.2e-82 276.1 34.5 4e-82 275.8 23.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein XRN_N PF03159.13 GAP84199.1 - 9.3e-103 342.7 0.0 1.5e-102 342.0 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-RanBP PF00641.13 GAP84201.1 - 1.8e-16 58.9 15.3 2e-09 36.3 2.0 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 GAP84201.1 - 1.8e-08 33.8 0.0 3.4e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 GAP84201.1 - 1.8e-06 28.3 0.0 3.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_6 PF14259.1 GAP84201.1 - 1.5e-05 24.8 0.0 3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 GAP84201.1 - 4.1 7.2 11.6 0.5 10.2 0.9 2.4 2 0 0 2 2 2 0 Double zinc ribbon Pmp3 PF01679.12 GAP84202.1 - 1.3e-18 66.4 6.9 1.6e-18 66.1 4.8 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF2371 PF10177.4 GAP84202.1 - 0.048 13.5 0.1 0.053 13.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) PA14_2 PF10528.4 GAP84204.1 - 2e-22 79.2 0.3 2.7e-22 78.8 0.2 1.2 1 0 0 1 1 1 1 GLEYA domain TMEM52 PF14979.1 GAP84205.1 - 0.056 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Transmembrane 52 SH3_7 PF12914.2 GAP84205.1 - 0.11 12.3 1.0 12 5.7 0.1 2.8 3 0 0 3 3 3 0 SH3 domain of SH3b2 type ETRAMP PF09716.5 GAP84205.1 - 0.52 10.3 3.6 1.7 8.6 0.0 3.0 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) HET PF06985.6 GAP84207.1 - 1.6e-24 86.6 0.1 3e-24 85.7 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.20 GAP84207.1 - 6e-17 62.0 0.9 1.2e-16 61.0 0.6 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP84207.1 - 2.3e-08 33.9 0.4 5.3e-08 32.7 0.3 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAP84207.1 - 2.6e-08 33.6 0.0 4.2e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAP84207.1 - 0.0015 18.5 0.1 0.0031 17.5 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 GAP84207.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF3425 PF11905.3 GAP84208.1 - 5.7e-31 107.2 0.0 9.5e-31 106.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) AAA PF00004.24 GAP84209.1 - 5.9e-14 52.4 0.0 1.6e-13 51.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAP84209.1 - 6.9e-05 22.9 0.0 0.00024 21.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 GAP84209.1 - 0.0017 19.1 0.0 0.0051 17.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAP84209.1 - 0.0019 18.3 0.4 0.028 14.5 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 GAP84209.1 - 0.0026 17.4 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) CPT PF07931.7 GAP84209.1 - 0.004 16.7 0.0 0.012 15.2 0.0 1.8 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_19 PF13245.1 GAP84209.1 - 0.01 15.6 0.1 0.049 13.3 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 GAP84209.1 - 0.033 14.1 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAP84209.1 - 0.058 13.7 0.1 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 GAP84209.1 - 0.092 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Ank_2 PF12796.2 GAP84210.1 - 4.8e-76 251.1 0.0 1.3e-15 57.4 0.2 6.4 1 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 GAP84210.1 - 5e-71 231.1 1.3 1.8e-07 30.5 0.0 11.8 12 0 0 12 12 12 10 Ankyrin repeat Ank_3 PF13606.1 GAP84210.1 - 1.6e-55 179.4 0.8 8.2e-05 22.4 0.0 11.5 11 0 0 11 11 11 10 Ankyrin repeat Ank_4 PF13637.1 GAP84210.1 - 4.8e-51 170.2 0.0 2e-09 37.7 0.0 8.4 3 2 6 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP84210.1 - 2.4e-48 161.0 1.9 5.3e-10 39.2 0.1 9.3 4 3 5 9 9 9 9 Ankyrin repeats (many copies) Amidase PF01425.16 GAP84211.1 - 3.5e-07 29.4 0.0 3.9e-07 29.2 0.0 1.0 1 0 0 1 1 1 1 Amidase ABC2_membrane PF01061.19 GAP84212.1 - 3.4e-36 124.4 17.6 6.9e-36 123.3 12.2 1.6 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 GAP84212.1 - 3.7e-24 85.5 0.0 8.5e-24 84.4 0.0 1.6 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 GAP84212.1 - 2e-09 37.8 0.0 6.8e-09 36.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 GAP84212.1 - 2.4e-06 26.8 26.4 2.4e-06 26.8 18.3 2.2 1 1 1 2 2 2 1 ABC-2 family transporter protein hEGF PF12661.2 GAP84212.1 - 8.6e-05 22.3 22.0 0.024 14.6 2.8 4.3 3 0 0 3 3 3 2 Human growth factor-like EGF AAA_25 PF13481.1 GAP84212.1 - 0.00079 18.8 0.0 0.18 11.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 GAP84212.1 - 0.0029 16.7 0.0 1.6 7.7 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 GAP84212.1 - 0.017 14.3 0.0 0.037 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 GAP84212.1 - 0.026 14.0 0.1 0.057 12.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.14 GAP84212.1 - 0.034 13.3 0.0 0.21 10.7 0.0 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 GAP84212.1 - 0.046 13.8 0.0 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 GAP84212.1 - 0.072 13.0 0.1 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.1 GAP84212.1 - 0.14 12.0 0.0 0.37 10.7 0.0 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 GAP84212.1 - 0.17 12.2 0.2 0.3 11.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain EphA2_TM PF14575.1 GAP84212.1 - 0.3 11.5 1.5 0.9 9.9 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain EGF_2 PF07974.8 GAP84212.1 - 5 7.3 38.0 0.18 12.0 8.4 4.1 4 0 0 4 4 4 0 EGF-like domain DUF4585 PF15232.1 GAP84213.1 - 0.056 13.2 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4585) NGP1NT PF08153.7 GAP84214.1 - 2.6e-46 156.7 0.0 4.4e-46 156.0 0.0 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 GAP84214.1 - 1.5e-19 70.0 0.0 7.1e-16 58.2 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 GAP84214.1 - 8.6e-06 25.1 0.0 0.00018 20.8 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 GAP84214.1 - 0.00063 18.9 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 GAP84214.1 - 0.0056 16.5 0.2 1.7 8.4 0.0 3.2 2 1 1 3 3 3 1 Dynamin family Arf PF00025.16 GAP84214.1 - 0.037 13.2 0.1 0.28 10.4 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family But2 PF09792.4 GAP84215.1 - 3.9e-14 52.6 0.0 1.4e-13 50.8 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain Glyco_hydro_18 PF00704.23 GAP84216.1 - 2.1e-24 86.6 2.5 2.1e-24 86.6 1.7 2.2 2 1 0 3 3 3 1 Glycosyl hydrolases family 18 CBM_1 PF00734.13 GAP84216.1 - 6.1e-12 44.9 13.4 2e-11 43.3 9.3 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain NHL PF01436.16 GAP84218.1 - 0.0012 18.7 0.1 0.062 13.2 0.0 3.0 3 0 0 3 3 3 1 NHL repeat Arylesterase PF01731.15 GAP84218.1 - 0.038 13.9 0.0 0.85 9.6 0.0 2.5 2 0 0 2 2 2 0 Arylesterase Toxin_65 PF15543.1 GAP84219.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 65 AMP-binding PF00501.23 GAP84221.1 - 2.2e-36 125.1 1.0 4e-13 48.5 0.7 5.2 3 2 1 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 GAP84221.1 - 2.9e-11 42.7 0.0 6.8e-11 41.5 0.0 1.6 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.20 GAP84221.1 - 1.4e-07 31.6 0.0 0.018 15.3 0.0 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding PF00501.23 GAP84222.1 - 1.1e-17 63.5 0.1 1.7e-17 62.9 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 GAP84222.1 - 1.2e-11 44.6 0.1 2.8e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Condensation PF00668.15 GAP84222.1 - 4.6e-08 32.2 0.0 7.8e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Condensation domain GH3 PF03321.8 GAP84222.1 - 0.0037 15.8 0.0 0.0052 15.3 0.0 1.1 1 0 0 1 1 1 1 GH3 auxin-responsive promoter Abhydrolase_6 PF12697.2 GAP84223.1 - 7.1e-13 48.9 0.3 1.2e-12 48.2 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP84223.1 - 2e-06 27.5 0.0 4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP84223.1 - 3.1e-05 23.7 0.0 4.4e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 GAP84223.1 - 0.0018 17.0 0.0 0.0027 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Thioesterase PF00975.15 GAP84223.1 - 0.025 14.8 0.0 0.042 14.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain WD40 PF00400.27 GAP84227.1 - 1.6e-43 145.0 3.3 8.8e-10 38.0 0.0 7.7 7 1 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 GAP84227.1 - 1.1e-05 25.2 0.7 0.078 12.6 0.0 3.3 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Cornichon PF03311.9 GAP84228.1 - 2.8e-54 182.6 10.8 3.2e-54 182.4 7.5 1.0 1 0 0 1 1 1 1 Cornichon protein Peptidase_M24 PF00557.19 GAP84229.1 - 5.3e-44 150.2 0.1 6.7e-44 149.9 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 GAP84229.1 - 5e-06 26.2 4.2 5e-06 26.2 2.9 2.3 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.11 GAP84229.1 - 1.2 8.8 5.6 4.5 7.0 3.9 2.1 1 0 0 1 1 1 0 HIT zinc finger EGF_CA PF07645.10 GAP84229.1 - 3.6 7.6 9.3 2.9 7.9 1.2 2.8 1 1 1 2 2 2 0 Calcium-binding EGF domain FAD_binding_3 PF01494.14 GAP84230.1 - 5.3e-18 65.2 0.0 8.5e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAP84230.1 - 1.6e-05 24.8 0.1 3.8e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAP84230.1 - 3.7e-05 24.0 0.0 0.00019 21.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAP84230.1 - 0.0002 20.4 0.0 0.00062 18.7 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 GAP84230.1 - 0.0017 17.2 0.0 0.0042 15.9 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 GAP84230.1 - 0.0026 17.6 0.1 0.0063 16.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAP84230.1 - 0.0041 15.6 0.0 0.006 15.0 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 GAP84230.1 - 0.017 14.2 0.1 0.074 12.1 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase SE PF08491.5 GAP84230.1 - 0.025 13.4 0.0 0.048 12.4 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase 3HCDH_N PF02737.13 GAP84230.1 - 0.048 13.3 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 GAP84230.1 - 0.062 12.3 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.16 GAP84230.1 - 0.08 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.20 GAP84231.1 - 4.1e-21 75.5 0.5 9e-21 74.4 0.3 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP84231.1 - 6e-10 39.0 0.1 1.1e-09 38.2 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAP84231.1 - 1.2e-06 28.5 0.0 2.1e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAP84231.1 - 1.5e-06 27.8 0.0 2.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAP84231.1 - 0.00025 20.3 0.1 0.00039 19.7 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAP84231.1 - 0.0023 17.9 0.4 0.0056 16.7 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding TIM-br_sig_trns PF09370.5 GAP84232.1 - 4.1e-126 419.5 2.1 4.6e-126 419.3 1.5 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein Amidohydro_2 PF04909.9 GAP84232.1 - 0.00019 21.1 1.7 0.00098 18.7 1.2 2.2 1 1 0 1 1 1 1 Amidohydrolase NMO PF03060.10 GAP84232.1 - 0.57 9.2 7.2 0.055 12.6 1.8 1.6 2 0 0 2 2 2 0 Nitronate monooxygenase UPF0261 PF06792.6 GAP84233.1 - 2.1e-08 33.0 0.0 2.1e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) UPF0261 PF06792.6 GAP84234.1 - 3.3e-108 361.7 0.4 3.8e-108 361.5 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) RmlD_sub_bind PF04321.12 GAP84234.1 - 0.13 11.0 0.8 1.9 7.3 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain SR-25 PF10500.4 GAP84234.1 - 0.4 10.1 7.8 0.6 9.5 5.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 GAP84234.1 - 2.1 8.4 6.9 3.2 7.8 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) WD40 PF00400.27 GAP84236.1 - 3.2e-59 194.8 31.4 1.6e-09 37.2 0.0 11.7 12 0 0 12 12 12 8 WD domain, G-beta repeat NACHT PF05729.7 GAP84236.1 - 5.5e-09 35.8 0.1 1.3e-08 34.7 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 GAP84236.1 - 6.3e-05 23.0 0.0 0.00022 21.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Nup160 PF11715.3 GAP84236.1 - 0.00033 18.9 0.0 0.016 13.3 0.0 3.0 3 0 0 3 3 3 1 Nucleoporin Nup120/160 AAA_22 PF13401.1 GAP84236.1 - 0.0068 16.5 0.1 0.054 13.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 GAP84236.1 - 0.034 13.5 0.0 0.074 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 GAP84236.1 - 0.13 11.2 1.2 0.18 10.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 GAP84236.1 - 0.15 11.7 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain KAP_NTPase PF07693.9 GAP84236.1 - 0.28 10.1 1.9 0.47 9.3 0.7 1.7 2 0 0 2 2 2 0 KAP family P-loop domain AAA_10 PF12846.2 GAP84236.1 - 0.37 10.1 1.1 0.74 9.1 0.1 2.0 3 0 0 3 3 3 0 AAA-like domain GATase_5 PF13507.1 GAP84237.1 - 1.8e-94 315.4 0.0 2.7e-94 314.9 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 GAP84237.1 - 2.5e-38 131.4 0.1 4.8e-18 65.6 0.0 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 GAP84237.1 - 6.2e-21 74.4 0.0 2.7e-20 72.4 0.0 2.2 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Abhydrolase_6 PF12697.2 GAP84238.1 - 2e-12 47.4 1.6 2e-12 47.4 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP84238.1 - 1.1e-08 34.9 0.0 1.8e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP84238.1 - 1.6e-05 24.6 0.0 3.1e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cupin_2 PF07883.6 GAP84239.1 - 2.6e-14 52.4 0.2 3.7e-14 51.9 0.2 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 GAP84239.1 - 7e-05 22.2 0.0 9.8e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 GAP84239.1 - 8.4e-05 21.8 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.14 GAP84239.1 - 0.00013 21.6 0.2 0.00017 21.2 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain GPI PF06560.6 GAP84239.1 - 0.012 14.6 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) ARD PF03079.9 GAP84239.1 - 0.059 13.3 0.1 0.084 12.8 0.0 1.1 1 0 0 1 1 1 0 ARD/ARD' family FdtA PF05523.6 GAP84239.1 - 0.1 12.1 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 WxcM-like, C-terminal DUF3506 PF12014.3 GAP84240.1 - 7.6e-44 148.8 0.0 1.1e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) DUF1769 PF08588.5 GAP84241.1 - 6.2e-28 96.5 1.3 1.5e-27 95.3 0.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) Ada3 PF10198.4 GAP84242.1 - 6.4e-42 142.3 0.3 1.8e-41 140.9 0.0 1.9 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 Amidohydro_1 PF01979.15 GAP84243.1 - 1.9e-61 208.5 1.7 3.3e-61 207.7 1.2 1.4 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 GAP84243.1 - 2.5e-54 182.5 2.2 4.7e-54 181.6 1.5 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 GAP84243.1 - 1e-39 134.4 0.3 1.1e-38 131.1 0.0 2.3 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 GAP84243.1 - 1.6e-39 133.9 0.8 2.8e-39 133.1 0.1 1.8 2 0 0 2 2 2 1 Urease, gamma subunit Amidohydro_5 PF13594.1 GAP84243.1 - 1.4e-06 28.0 2.0 3.6e-06 26.7 1.4 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 GAP84243.1 - 0.00025 20.3 5.1 0.00079 18.7 0.7 2.7 1 1 0 2 2 2 1 Amidohydrolase family Amidohydro_2 PF04909.9 GAP84243.1 - 0.0016 18.0 0.3 0.0046 16.5 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase HMG_box PF00505.14 GAP84244.1 - 9e-08 32.2 0.1 2e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 GAP84244.1 - 4.3e-05 23.8 0.2 0.00019 21.7 0.0 2.2 2 0 0 2 2 2 1 HMG-box domain Het-C PF07217.6 GAP84245.1 - 4.8e-258 857.3 0.0 6.4e-258 856.9 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Zn_dep_PLPC PF00882.13 GAP84245.1 - 0.082 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Zinc dependent phospholipase C Glyco_hydro_45 PF02015.11 GAP84246.1 - 5.7e-84 281.1 20.9 6.8e-84 280.9 14.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 GMC_oxred_C PF05199.8 GAP84247.1 - 6.8e-16 58.8 0.0 1.7e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 GAP84247.1 - 1.7e-07 30.7 0.1 1.2e-05 24.6 0.0 2.6 3 0 0 3 3 3 1 GMC oxidoreductase ApbA PF02558.11 GAP84247.1 - 9.9e-06 25.0 0.1 1.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 GAP84247.1 - 1.9e-05 24.6 0.0 0.017 15.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAP84247.1 - 0.0002 20.5 0.2 0.00035 19.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 GAP84247.1 - 0.00036 20.2 0.1 0.00062 19.4 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 GAP84247.1 - 0.0048 16.8 0.1 0.011 15.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAP84247.1 - 0.012 15.9 0.1 0.03 14.7 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP84247.1 - 0.013 15.5 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAP84247.1 - 0.021 13.7 0.3 0.091 11.6 0.2 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 GAP84247.1 - 0.021 14.1 0.1 0.038 13.3 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 GAP84247.1 - 0.04 13.6 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.9 GAP84247.1 - 0.057 11.8 0.2 0.1 11.0 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein 2-Hacid_dh_C PF02826.14 GAP84247.1 - 0.12 11.5 0.1 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 GAP84247.1 - 0.16 12.0 0.2 0.27 11.2 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_2 PF00890.19 GAP84247.1 - 0.16 10.7 0.0 6.4 5.5 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Fructosamin_kin PF03881.9 GAP84249.1 - 1.4e-12 47.2 0.0 5.5e-12 45.2 0.0 1.7 1 1 1 2 2 2 1 Fructosamine kinase HET PF06985.6 GAP84250.1 - 1.1e-26 93.6 0.0 2.6e-26 92.4 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 GAP84251.1 - 4.7e-26 91.6 0.3 7.6e-26 90.9 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Surp PF01805.15 GAP84251.1 - 0.058 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Surp module DAO PF01266.19 GAP84252.1 - 9.7e-22 77.3 0.0 1.7e-21 76.5 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAP84252.1 - 1.1e-07 31.0 0.0 1.6e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 GAP84252.1 - 4.8e-05 23.3 0.0 7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP84252.1 - 0.00019 21.3 0.2 0.00054 19.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 GAP84252.1 - 0.0046 15.8 0.2 0.0069 15.2 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A ApbA PF02558.11 GAP84252.1 - 0.0051 16.2 0.8 0.011 15.2 0.0 2.0 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 GAP84252.1 - 0.0059 15.1 0.5 0.0079 14.7 0.3 1.1 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 GAP84252.1 - 0.012 14.7 0.1 0.022 13.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 GAP84252.1 - 0.013 15.8 1.1 0.033 14.5 0.5 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 GAP84252.1 - 0.029 14.7 0.1 0.063 13.7 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Lycopene_cycl PF05834.7 GAP84252.1 - 0.047 12.5 0.1 0.065 12.1 0.1 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 GAP84252.1 - 0.058 12.4 0.2 0.089 11.8 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 GAP84252.1 - 0.059 12.7 0.2 0.095 12.0 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 GAP84252.1 - 0.14 11.9 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 GAP84252.1 - 0.15 11.6 0.2 0.25 10.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 GAP84252.1 - 0.17 12.1 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Acyl-CoA_dh_1 PF00441.19 GAP84253.1 - 2.5e-29 102.3 6.5 4.9e-29 101.3 4.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAP84253.1 - 4.4e-20 72.3 0.0 1.5e-19 70.6 0.0 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 GAP84253.1 - 3.3e-19 68.1 3.1 6.3e-19 67.2 2.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 GAP84253.1 - 0.00046 20.4 3.3 0.00046 20.4 2.3 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DUF2404 PF10296.4 GAP84254.1 - 0.00027 21.0 0.0 0.002 18.2 0.0 2.1 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) PIP5K PF01504.13 GAP84255.1 - 4e-59 199.7 0.2 7.7e-59 198.8 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 GAP84255.1 - 4.1e-25 88.3 0.0 6.1e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 GAP84255.1 - 3.6e-12 46.0 11.0 3.6e-12 46.0 7.6 2.0 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.11 GAP84255.1 - 0.85 9.5 9.7 0.12 12.2 2.8 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger AMP-binding PF00501.23 GAP84257.1 - 1.2e-67 228.1 0.0 5.8e-34 117.1 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 GAP84257.1 - 2.5e-10 41.1 0.0 8.2e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IF4E PF01652.13 GAP84258.1 - 2.2e-60 202.9 0.1 2.6e-60 202.6 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Methyltransf_16 PF10294.4 GAP84259.1 - 1.7e-15 56.9 0.0 3e-14 52.8 0.0 2.1 1 1 1 2 2 2 1 Putative methyltransferase 2OG-FeII_Oxy_3 PF13640.1 GAP84259.1 - 5.5e-11 42.8 0.0 1.1e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_18 PF12847.2 GAP84259.1 - 2.3e-05 24.9 0.0 5.4e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain 2OG-FeII_Oxy_4 PF13661.1 GAP84259.1 - 7.2e-05 22.3 0.0 0.00031 20.3 0.0 2.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_23 PF13489.1 GAP84259.1 - 0.0061 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP84259.1 - 0.018 15.5 0.0 0.061 13.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 GAP84259.1 - 0.02 14.2 0.0 0.27 10.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_11 PF08241.7 GAP84259.1 - 0.084 13.3 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain APH PF01636.18 GAP84261.1 - 6.7e-15 55.4 0.0 9.4e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAP84261.1 - 0.00027 20.5 0.0 0.0004 20.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Sugar_tr PF00083.19 GAP84262.1 - 2.4e-103 346.1 19.9 2.7e-103 345.9 13.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP84262.1 - 7.7e-27 93.9 59.4 8.6e-23 80.6 21.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 GAP84262.1 - 8.6e-05 20.7 1.1 0.00014 20.0 0.7 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans_2 PF11951.3 GAP84263.1 - 1.9e-20 72.7 2.5 6.9e-20 70.9 1.7 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 GAP84264.1 - 1.5e-17 64.0 0.5 2e-17 63.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP84264.1 - 4.2e-10 39.5 0.2 6e-10 39.0 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAP84264.1 - 2.1e-06 27.6 0.0 2.7e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 GAP84264.1 - 0.056 12.1 0.0 0.12 11.0 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAP84264.1 - 0.073 12.4 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Transketolase_N PF00456.16 GAP84265.1 - 6.7e-121 403.1 0.0 1.3e-120 402.2 0.0 1.5 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 GAP84265.1 - 5.4e-40 136.7 0.1 3e-39 134.3 0.0 2.3 3 0 0 3 3 3 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 GAP84265.1 - 1.3e-10 40.6 0.0 7.6e-10 38.1 0.0 1.9 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.15 GAP84265.1 - 9.4e-06 25.5 0.0 2.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.15 GAP84265.1 - 1.9e-05 23.5 0.0 2.9e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_N PF02776.13 GAP84265.1 - 0.016 14.6 0.1 0.85 9.0 0.0 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Peptidase_C14 PF00656.17 GAP84266.1 - 7e-22 78.3 0.0 1.2e-21 77.5 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.13 GAP84266.1 - 0.083 12.1 0.0 0.44 9.7 0.0 2.0 2 0 0 2 2 2 0 Peptidase C13 family Actin PF00022.14 GAP84268.1 - 6.6e-140 465.9 0.0 7.5e-140 465.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 GAP84268.1 - 8.8e-07 27.8 0.1 0.01 14.4 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein D-ser_dehydrat PF14031.1 GAP84269.1 - 5.3e-23 81.0 0.0 1e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 GAP84269.1 - 6.2e-09 35.7 0.0 1.9e-08 34.1 0.0 1.7 2 0 0 2 2 2 1 Alanine racemase, N-terminal domain Nucleoplasmin PF03066.10 GAP84269.1 - 0.024 14.1 2.4 0.044 13.2 1.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin Daxx PF03344.10 GAP84269.1 - 0.19 10.1 3.5 0.26 9.7 2.4 1.1 1 0 0 1 1 1 0 Daxx Family Sporozoite_P67 PF05642.6 GAP84269.1 - 0.22 9.3 1.5 0.31 8.8 1.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PBP1_TM PF14812.1 GAP84269.1 - 1.8 8.9 9.4 3.4 8.0 6.5 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.9 GAP84269.1 - 3.9 5.3 6.4 5.5 4.9 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein HMG-CoA_red PF00368.13 GAP84270.1 - 4.9e-153 509.1 6.9 6.2e-153 508.8 4.8 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 GAP84270.1 - 2e-46 157.4 0.6 3.3e-46 156.7 0.4 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 GAP84270.1 - 5.8e-13 48.5 6.8 1.9e-11 43.6 4.7 2.5 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 GAP84270.1 - 1.9e-08 32.7 0.5 1.9e-08 32.7 0.3 1.7 2 0 0 2 2 2 1 Patched family Isochorismatase PF00857.15 GAP84272.1 - 2.5e-14 53.5 0.0 6.3e-14 52.2 0.0 1.6 1 1 0 1 1 1 1 Isochorismatase family Abhydrolase_3 PF07859.8 GAP84273.1 - 1.3e-26 93.4 0.1 1.7e-26 93.1 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 GAP84273.1 - 3.4e-13 48.9 0.0 6.8e-12 44.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 GAP84273.1 - 0.0015 18.3 0.2 0.0022 17.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 GAP84273.1 - 0.002 16.9 0.8 0.076 11.7 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family DUF2063 PF09836.4 GAP84273.1 - 0.17 11.8 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2063) DHquinase_II PF01220.14 GAP84274.1 - 1.5e-56 189.6 0.1 1.7e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Reticulon PF02453.12 GAP84275.1 - 0.29 10.7 2.1 5.4 6.6 0.4 2.2 2 0 0 2 2 2 0 Reticulon DUF3844 PF12955.2 GAP84276.1 - 2.7e-36 123.7 3.4 4.8e-36 122.9 2.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) NTR2 PF15458.1 GAP84277.1 - 3.8e-37 127.9 16.8 1.7e-33 115.9 5.1 2.9 2 1 1 3 3 3 2 Nineteen complex-related protein 2 TMF_TATA_bd PF12325.3 GAP84277.1 - 0.1 12.3 0.3 0.1 12.3 0.2 2.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding LSM PF01423.17 GAP84278.1 - 2.5e-19 68.5 0.6 2.8e-19 68.4 0.4 1.0 1 0 0 1 1 1 1 LSM domain Glyco_hydro_76 PF03663.9 GAP84279.1 - 1.9e-127 425.6 1.5 2.3e-127 425.3 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Caudo_TAP PF02413.12 GAP84280.1 - 0.19 11.8 7.0 0.075 13.2 2.9 1.8 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein DUF336 PF03928.9 GAP84280.1 - 4.9 6.9 7.5 0.42 10.4 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF336) Glyco_tranf_2_3 PF13641.1 GAP84281.1 - 1.8e-19 70.4 0.0 2.4e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 GAP84281.1 - 2.1e-07 30.3 0.0 4.8e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 GAP84281.1 - 5e-05 23.0 0.0 9.4e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Meth_synt_2 PF01717.13 GAP84282.1 - 4.1e-07 29.2 0.0 4e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain YrhK PF14145.1 GAP84283.1 - 3.1e-05 23.5 22.0 0.059 13.0 0.1 4.6 4 1 0 4 4 4 3 YrhK-like protein Pkinase PF00069.20 GAP84284.1 - 6.7e-63 212.2 0.0 1.3e-62 211.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP84284.1 - 1.5e-35 122.5 0.0 1.5e-30 106.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAP84284.1 - 1.1e-06 27.7 0.0 0.0013 17.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 GAP84284.1 - 0.0062 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 GAP84284.1 - 0.011 15.0 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 GAP84284.1 - 0.084 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DAHP_synth_2 PF01474.11 GAP84285.1 - 1.8e-194 646.1 0.0 2e-194 645.9 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family ASL_C PF08328.6 GAP84286.1 - 0.012 15.4 0.1 0.014 15.1 0.1 1.2 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal Secretin_N PF03958.12 GAP84286.1 - 0.2 11.8 1.2 0.29 11.3 0.8 1.2 1 0 0 1 1 1 0 Bacterial type II/III secretion system short domain Peptidase_M35 PF02102.10 GAP84286.1 - 0.86 8.1 5.9 1.1 7.8 4.1 1.1 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family RR_TM4-6 PF06459.7 GAP84286.1 - 1.3 8.8 5.2 1.5 8.6 3.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 p450 PF00067.17 GAP84287.1 - 2e-48 165.0 0.0 2.3e-47 161.5 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 Na_Ca_ex PF01699.19 GAP84288.1 - 2.9e-38 130.6 31.9 2.4e-22 79.0 9.7 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Zip PF02535.17 GAP84288.1 - 0.0002 20.5 0.3 0.0002 20.5 0.2 2.3 3 0 0 3 3 3 1 ZIP Zinc transporter SPRY PF00622.23 GAP84289.1 - 5.6e-05 23.2 0.0 0.0001 22.4 0.0 1.4 1 0 0 1 1 1 1 SPRY domain WD40 PF00400.27 GAP84290.1 - 1.1e-07 31.4 0.3 0.002 17.9 0.0 4.8 4 0 0 4 4 4 1 WD domain, G-beta repeat Abhydrolase_6 PF12697.2 GAP84290.1 - 1.1e-06 28.7 0.2 2.2e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 GAP84290.1 - 1.9e-05 24.0 0.0 4.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 GAP84290.1 - 2.3e-05 24.1 0.0 4.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein NACHT PF05729.7 GAP84290.1 - 6.9e-05 22.5 0.0 0.00016 21.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 GAP84290.1 - 0.0022 17.9 0.0 0.006 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Abhydrolase_5 PF12695.2 GAP84290.1 - 0.0074 16.0 0.0 0.03 14.0 0.0 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2075 PF09848.4 GAP84290.1 - 0.013 14.4 0.0 0.025 13.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 GAP84290.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 GAP84290.1 - 0.055 13.6 0.0 0.53 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF1375 PF07119.7 GAP84291.1 - 0.15 11.8 1.5 3.1 7.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1375) TIG PF01833.19 GAP84291.1 - 2.5 8.1 7.9 0.36 10.8 2.0 2.2 3 0 0 3 3 3 0 IPT/TIG domain Fructosamin_kin PF03881.9 GAP84292.1 - 1.1e-27 96.7 0.0 1.3e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 GAP84292.1 - 0.0076 16.0 0.1 0.016 14.9 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family ADH_N PF08240.7 GAP84293.1 - 1.3e-27 95.7 1.4 1.3e-27 95.7 1.0 2.1 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAP84293.1 - 1.4e-14 53.7 0.0 2.1e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase S1-like PF14444.1 GAP84293.1 - 0.062 13.0 0.0 3.1 7.5 0.0 2.7 2 0 0 2 2 2 0 S1-like ATP-synt_G PF04718.10 GAP84294.1 - 4.1e-27 94.8 3.0 1.2e-26 93.3 0.3 2.1 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit Apolipoprotein PF01442.13 GAP84294.1 - 0.059 12.8 0.9 0.13 11.7 0.1 1.7 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF3037 PF11236.3 GAP84294.1 - 0.15 12.1 0.3 0.35 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) Methyltransf_23 PF13489.1 GAP84295.1 - 3e-17 62.8 0.0 5.2e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP84295.1 - 8.5e-08 31.9 0.0 8.8e-07 28.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP84295.1 - 5.5e-07 30.1 0.1 9.4e-06 26.1 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP84295.1 - 6.9e-07 29.6 0.0 1.7e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP84295.1 - 1e-05 25.8 0.0 3.2e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP84295.1 - 6.4e-05 22.9 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP84295.1 - 6.8e-05 23.2 0.1 0.00068 20.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP84295.1 - 0.026 13.6 0.0 0.091 11.8 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family MTS PF05175.9 GAP84295.1 - 0.027 13.8 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 GAP84295.1 - 0.084 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase TFIIA PF03153.8 GAP84297.1 - 1.7e-80 271.7 18.9 1e-79 269.1 13.1 1.8 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 GAP84297.1 - 0.64 7.8 4.6 0.79 7.5 3.2 1.1 1 0 0 1 1 1 0 Nop14-like family WD40 PF00400.27 GAP84298.1 - 7.1e-25 85.9 16.7 1.7e-06 27.6 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 GAP84298.1 - 3.4e-06 26.9 0.4 0.00043 20.0 0.2 2.6 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 GAP84298.1 - 0.044 13.2 0.0 0.55 9.7 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.2 GAP84298.1 - 0.084 12.5 8.3 3.2 7.4 0.1 3.9 4 1 0 4 4 4 0 Transcription factor IIIC subunit delta N-term Kelch_4 PF13418.1 GAP84299.1 - 6.8e-26 89.7 6.0 4.9e-08 32.6 0.0 5.3 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 GAP84299.1 - 6.4e-24 83.4 2.1 3.5e-06 26.8 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 GAP84299.1 - 4.5e-22 77.2 3.2 0.00014 21.8 0.0 5.3 4 1 2 6 6 6 4 Kelch motif Kelch_3 PF13415.1 GAP84299.1 - 4.7e-21 74.3 3.4 4.6e-07 29.8 0.0 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.20 GAP84299.1 - 3.9e-18 64.7 0.3 6.3e-05 22.4 0.0 4.8 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.10 GAP84299.1 - 1.8e-17 62.3 2.6 0.00019 21.0 0.0 4.6 4 0 0 4 4 4 4 Kelch motif BTB PF00651.26 GAP84299.1 - 7.4e-10 38.8 0.0 1.3e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_4 PF13894.1 GAP84300.1 - 0.0042 17.3 15.1 0.79 10.1 0.1 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 GAP84300.1 - 0.35 11.3 20.3 0.4 11.1 0.5 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAP84300.1 - 0.62 10.4 22.5 0.03 14.6 2.2 3.7 4 0 0 4 4 4 0 Zinc-finger double domain zf-BED PF02892.10 GAP84300.1 - 0.66 9.7 6.9 0.78 9.5 2.1 2.6 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.3 GAP84300.1 - 0.96 9.6 12.6 0.4 10.8 2.1 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding HIG_1_N PF04588.8 GAP84301.1 - 8.3e-08 31.8 1.4 8.3e-08 31.8 1.0 1.9 2 0 0 2 2 2 1 Hypoxia induced protein conserved region TraQ PF09679.5 GAP84301.1 - 0.19 11.6 1.0 2.6 8.0 0.0 2.4 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) Romo1 PF10247.4 GAP84301.1 - 3.2 8.0 5.8 2.7 8.2 2.7 1.8 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Kelch_4 PF13418.1 GAP84302.1 - 4.4e-45 151.2 18.8 5e-11 42.1 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 GAP84302.1 - 4.3e-44 147.7 22.5 1.6e-11 44.0 0.0 7.1 8 0 0 8 8 8 6 Galactose oxidase, central domain Kelch_5 PF13854.1 GAP84302.1 - 1.4e-41 139.8 14.2 8.5e-07 28.7 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 GAP84302.1 - 1.2e-35 120.7 13.7 5.6e-07 29.0 0.3 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 GAP84302.1 - 1.5e-33 113.5 13.6 7.3e-07 29.0 0.0 6.4 3 2 3 6 6 6 6 Kelch motif Kelch_2 PF07646.10 GAP84302.1 - 1.1e-26 91.5 18.2 1.4e-05 24.6 0.2 6.6 6 1 0 6 6 6 6 Kelch motif Dus PF01207.12 GAP84303.1 - 6.3e-37 127.0 0.0 3.7e-27 94.9 0.0 2.6 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 GAP84303.1 - 0.77 9.5 7.2 7.7 6.3 0.5 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Bap31 PF05529.7 GAP84304.1 - 6.9e-64 214.8 5.2 7.8e-64 214.6 3.6 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Phage_GP20 PF06810.6 GAP84304.1 - 0.005 16.2 2.1 0.0076 15.6 1.5 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 TMF_TATA_bd PF12325.3 GAP84304.1 - 0.05 13.3 2.2 0.098 12.3 1.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 GAP84304.1 - 0.093 12.3 0.5 0.15 11.6 0.4 1.4 1 0 0 1 1 1 0 IncA protein DUF4446 PF14584.1 GAP84304.1 - 0.15 11.9 0.1 0.15 11.9 0.1 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) TMF_DNA_bd PF12329.3 GAP84304.1 - 0.48 10.2 7.0 0.83 9.5 3.3 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 GAP84304.1 - 0.88 9.1 9.1 0.28 10.6 0.7 3.2 2 2 2 4 4 4 0 Septum formation initiator DUF1479 PF07350.7 GAP84305.1 - 3.9e-147 490.0 0.0 3.5e-128 427.6 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) HHH PF00633.18 GAP84307.1 - 0.014 15.0 0.0 0.033 13.8 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif zf-met2 PF12907.2 GAP84308.1 - 2.5e-16 59.3 0.9 3.8e-16 58.7 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 GAP84308.1 - 2.2e-07 31.5 12.8 2.2e-07 31.5 8.9 1.5 2 0 0 2 2 2 1 4F5 protein family CLAG PF03805.8 GAP84308.1 - 0.28 8.4 1.4 0.3 8.3 1.0 1.0 1 0 0 1 1 1 0 Cytoadherence-linked asexual protein DIOX_N PF14226.1 GAP84309.1 - 2.1e-31 108.8 0.0 3.9e-30 104.7 0.0 2.2 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAP84309.1 - 3.5e-14 52.9 0.0 1e-13 51.4 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.27 GAP84310.1 - 1.6e-09 37.2 0.1 0.0001 22.0 0.1 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat PPK2 PF03976.9 GAP84310.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) RNA_pol_N PF01194.12 GAP84311.1 - 2.7e-29 100.9 0.7 3.3e-29 100.6 0.5 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit XK-related PF09815.4 GAP84312.1 - 0.00012 21.1 0.0 0.00024 20.2 0.0 1.3 1 0 0 1 1 1 1 XK-related protein Myb_DNA-bind_6 PF13921.1 GAP84314.1 - 0.025 14.6 1.4 0.39 10.8 0.0 3.0 2 1 0 2 2 2 0 Myb-like DNA-binding domain Methyltransf_16 PF10294.4 GAP84315.1 - 2e-24 85.9 0.0 4.6e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 GAP84315.1 - 0.00044 20.8 0.0 0.0018 18.8 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP84315.1 - 0.0013 18.4 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP84315.1 - 0.0098 15.9 0.0 0.27 11.2 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.9 GAP84315.1 - 0.013 14.9 0.1 0.03 13.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 GAP84315.1 - 0.016 14.8 0.0 0.054 13.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 GAP84315.1 - 0.039 13.0 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Dynein_light PF01221.13 GAP84318.1 - 1.5e-41 140.2 1.2 1.7e-41 140.1 0.9 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 RRM_1 PF00076.17 GAP84319.1 - 6.1e-76 250.0 1.9 1.5e-17 62.9 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP84319.1 - 1.2e-64 214.2 2.1 8.3e-15 54.5 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP84319.1 - 8.2e-37 124.8 0.0 1.2e-06 28.2 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 GAP84319.1 - 4.7e-12 45.4 0.3 0.003 17.2 0.0 4.9 4 1 0 4 4 4 3 Limkain b1 Nup35_RRM_2 PF14605.1 GAP84319.1 - 1.6e-09 37.4 0.0 0.075 12.8 0.0 4.0 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 GAP84319.1 - 1.8e-09 37.3 0.7 0.19 11.6 0.0 5.0 5 0 0 5 5 5 4 RNA binding motif DUF4651 PF15513.1 GAP84319.1 - 0.013 14.9 0.0 0.36 10.3 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4651) SET_assoc PF11767.3 GAP84319.1 - 0.13 11.5 0.0 1.7e+02 1.6 0.0 4.0 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated TEA PF01285.13 GAP84320.1 - 1.7e-16 60.4 4.7 1.3e-11 44.3 0.0 3.0 2 1 0 3 3 3 2 TEA/ATTS domain family GAS PF13851.1 GAP84321.1 - 0.00093 18.4 17.7 0.00093 18.4 12.3 5.5 2 1 4 6 6 6 3 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 GAP84321.1 - 0.001 17.8 17.5 0.001 17.8 12.1 4.4 2 1 1 4 4 4 1 Spc7 kinetochore protein HET PF06985.6 GAP84322.1 - 3.3e-08 33.7 0.1 3.3e-06 27.2 0.0 2.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) TPR_12 PF13424.1 GAP84322.1 - 4.1e-07 29.8 12.3 0.00028 20.7 2.2 4.0 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.1 GAP84322.1 - 0.0018 18.1 12.8 0.09 12.7 0.2 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAP84322.1 - 0.016 15.8 18.6 8.5 7.3 0.4 7.1 6 2 1 7 7 7 0 Tetratricopeptide repeat TPR_5 PF12688.2 GAP84322.1 - 0.077 13.0 1.0 0.2 11.6 0.7 1.7 1 0 0 1 1 1 0 Tetratrico peptide repeat VCBS PF13517.1 GAP84323.1 - 1.3e-06 28.6 5.8 0.00047 20.4 1.3 3.6 2 1 1 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 GAP84323.1 - 2.5e-05 23.8 3.0 0.077 12.7 0.3 3.6 3 0 0 3 3 3 2 FG-GAP repeat EF-hand_6 PF13405.1 GAP84323.1 - 3.4e-05 23.3 0.5 1.3 9.1 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain P_proprotein PF01483.15 GAP84323.1 - 0.00017 21.2 3.3 0.89 9.3 0.1 4.1 2 1 2 4 4 4 1 Proprotein convertase P-domain TcdB_toxin_midN PF12256.3 GAP84323.1 - 0.001 18.5 2.3 1.1 8.6 0.1 2.9 2 1 1 3 3 3 2 Insecticide toxin TcdB middle/N-terminal region EF-hand_1 PF00036.27 GAP84323.1 - 0.0061 15.7 0.4 1.9 7.9 0.0 3.2 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.1 GAP84323.1 - 0.03 13.6 2.5 10 5.6 0.0 3.2 3 0 0 3 3 3 0 EF hand Cleaved_Adhesin PF07675.6 GAP84323.1 - 0.058 12.9 0.3 2.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Cleaved Adhesin Domain DUF756 PF05506.7 GAP84323.1 - 0.14 12.6 1.7 17 5.9 0.1 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF756) PNP_UDP_1 PF01048.15 GAP84324.1 - 2.4e-07 29.9 1.1 1.5e-06 27.3 0.8 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily Glyco_transf_90 PF05686.7 GAP84327.1 - 5.8e-07 28.5 1.1 0.00055 18.7 0.2 3.4 3 1 0 3 3 3 2 Glycosyl transferase family 90 EF-hand_9 PF14658.1 GAP84327.1 - 0.16 11.9 0.1 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain PX PF00787.19 GAP84328.1 - 2.8e-18 65.7 1.4 3.9e-18 65.2 0.0 2.0 3 0 0 3 3 3 1 PX domain Vps5 PF09325.5 GAP84328.1 - 1.5e-07 30.9 11.7 7.6e-05 22.0 1.4 2.3 2 1 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 GAP84328.1 - 9.6e-05 21.9 3.8 0.0002 20.9 2.6 1.5 1 1 0 1 1 1 1 BAR domain Reo_sigmaC PF04582.7 GAP84328.1 - 0.036 13.2 0.3 0.06 12.5 0.2 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein IncA PF04156.9 GAP84328.1 - 0.33 10.5 9.5 0.017 14.7 1.1 2.1 2 0 0 2 2 2 0 IncA protein DUF1664 PF07889.7 GAP84328.1 - 0.59 9.9 4.6 2.4 7.9 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) UPF0242 PF06785.6 GAP84328.1 - 2.1 6.9 9.8 0.24 10.0 1.7 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) DUF724 PF05266.9 GAP84328.1 - 4.7 6.7 9.8 6 6.4 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF724) Peptidase_S8 PF00082.17 GAP84330.1 - 9.5e-54 182.4 1.7 1.7e-53 181.5 1.2 1.4 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 GAP84330.1 - 7.1e-28 96.2 1.2 1.6e-27 95.0 0.8 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain Glyco_hydro_47 PF01532.15 GAP84332.1 - 6.8e-135 450.2 0.0 8.3e-135 449.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.17 GAP84332.1 - 0.038 13.6 0.0 0.084 12.5 0.0 1.5 1 0 0 1 1 1 0 PA domain Myb_DNA-binding PF00249.26 GAP84333.1 - 0.0027 17.6 1.2 0.13 12.3 0.1 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAP84333.1 - 0.028 14.5 6.2 0.53 10.4 0.4 3.3 3 0 0 3 3 3 0 Myb-like DNA-binding domain Fungal_trans PF04082.13 GAP84335.1 - 3.3e-07 29.4 0.1 7.1e-07 28.3 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP84335.1 - 0.05 13.5 10.8 0.11 12.4 1.3 2.6 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF983 PF06170.7 GAP84335.1 - 0.47 10.5 8.9 1.5 9.0 6.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF983) Cupin_2 PF07883.6 GAP84337.1 - 2.9e-10 39.4 0.6 2.6e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 GAP84337.1 - 0.0029 17.0 0.1 0.0056 16.1 0.0 1.5 1 1 0 1 1 1 1 Cupin 3-HAO PF06052.7 GAP84337.1 - 0.0032 16.8 0.1 0.016 14.5 0.0 1.8 1 1 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_3 PF05899.7 GAP84337.1 - 0.018 14.4 0.0 0.037 13.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF861) DUF4266 PF14086.1 GAP84337.1 - 3.6 8.1 10.2 6.8 7.2 7.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4266) NmrA PF05368.8 GAP84338.1 - 4.6e-58 196.2 0.0 5.8e-58 195.9 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAP84338.1 - 1.1e-16 61.3 0.0 1.6e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAP84338.1 - 3.3e-08 32.5 0.1 4.8e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAP84338.1 - 0.0006 19.3 0.1 0.0012 18.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 GAP84338.1 - 0.0024 16.9 0.1 0.0033 16.4 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 GAP84338.1 - 0.096 12.6 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Peroxin-13_N PF04088.8 GAP84339.1 - 5.3e-57 192.1 0.0 8.3e-57 191.5 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 GAP84339.1 - 2.5e-08 33.2 0.0 5e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAP84339.1 - 1.4e-07 30.8 0.0 2.9e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAP84339.1 - 3.4e-07 29.7 0.0 6e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain tRNA-synt_2 PF00152.15 GAP84340.1 - 2.7e-98 328.8 0.0 3.6e-98 328.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 GAP84340.1 - 0.00011 21.8 0.8 0.0092 15.5 0.2 2.3 1 1 1 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 GAP84340.1 - 0.015 14.4 0.1 0.1 11.7 0.1 2.0 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) ANTH PF07651.11 GAP84341.1 - 5.9e-65 218.7 0.2 7.5e-65 218.4 0.1 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 GAP84341.1 - 3.4e-07 30.1 0.0 5.5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 ENTH domain MAT1 PF06391.8 GAP84342.1 - 7e-26 91.0 7.0 9.5e-26 90.6 4.9 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 GAP84342.1 - 0.0021 17.6 7.8 0.0052 16.4 5.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) eIF-3_zeta PF05091.7 GAP84342.1 - 0.0029 16.3 1.3 0.0035 16.0 0.9 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) zf-UDP PF14569.1 GAP84342.1 - 0.017 14.8 1.4 0.04 13.6 0.9 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_2 PF13923.1 GAP84342.1 - 0.025 14.5 6.0 0.025 14.5 4.2 2.1 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MRP-S26 PF14943.1 GAP84342.1 - 0.16 11.4 12.5 0.33 10.4 8.7 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 zf-RING_5 PF14634.1 GAP84342.1 - 0.19 11.4 9.1 0.8 9.4 6.4 2.0 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_6 PF14835.1 GAP84342.1 - 0.4 10.4 4.6 0.52 10.1 2.1 2.1 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-RING_2 PF13639.1 GAP84342.1 - 0.72 9.7 7.4 2.3 8.1 5.1 1.9 1 1 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.1 GAP84342.1 - 5.4 6.6 8.6 25 4.5 6.2 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain CS PF04969.11 GAP84343.1 - 1.1e-15 57.8 0.0 2.4e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 CS domain Prefoldin_3 PF13758.1 GAP84344.1 - 1.3e-23 82.6 0.9 3.6e-23 81.1 0.6 1.8 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.2 GAP84344.1 - 2.2e-16 60.5 0.0 2.2e-16 60.5 0.0 4.0 3 2 2 5 5 5 1 Domain of unknown function (DUF3835) UBN2 PF14223.1 GAP84344.1 - 0.02 14.6 0.3 0.064 13.0 0.2 1.8 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DASH_Dad1 PF08649.5 GAP84344.1 - 0.23 11.1 0.7 0.44 10.2 0.0 1.7 2 0 0 2 2 2 0 DASH complex subunit Dad1 Prefoldin_2 PF01920.15 GAP84344.1 - 9.8 5.9 9.5 0.86 9.3 0.1 3.4 3 1 1 4 4 4 0 Prefoldin subunit RhgB_N PF09284.5 GAP84345.1 - 4.1e-83 278.5 10.1 6.9e-83 277.8 7.0 1.3 1 0 0 1 1 1 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 GAP84345.1 - 3.2e-49 166.7 0.0 7e-49 165.6 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 GAP84345.1 - 2.3e-15 56.4 0.7 9.4e-15 54.5 0.5 2.1 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 GAP84345.1 - 0.0007 19.6 0.2 0.0007 19.6 0.2 2.6 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain PEGA PF08308.6 GAP84345.1 - 0.027 14.2 0.1 0.25 11.1 0.0 2.4 2 0 0 2 2 2 0 PEGA domain Ig_2 PF13895.1 GAP84345.1 - 0.59 10.2 4.7 3 8.0 0.1 3.5 3 1 0 3 3 3 0 Immunoglobulin domain WLM PF08325.5 GAP84346.1 - 1.5e-56 191.2 0.0 1.5e-56 191.2 0.0 2.4 3 0 0 3 3 3 1 WLM domain zf-RanBP PF00641.13 GAP84346.1 - 0.0017 17.4 5.3 0.0017 17.4 3.7 3.3 2 1 1 3 3 3 2 Zn-finger in Ran binding protein and others PAT1 PF09770.4 GAP84346.1 - 0.031 12.5 9.5 0.048 11.9 6.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF45 PF01863.12 GAP84346.1 - 0.042 13.6 1.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF45 DZR PF12773.2 GAP84346.1 - 0.067 13.0 8.9 0.76 9.6 6.2 2.3 1 1 0 1 1 1 0 Double zinc ribbon K_channel_TID PF07941.6 GAP84346.1 - 0.48 10.6 9.8 0.16 12.2 2.4 2.8 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Glyco_hydro_71 PF03659.9 GAP84347.1 - 2.7e-65 220.3 0.1 3.3e-65 220.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 PPC PF04151.10 GAP84347.1 - 0.084 13.8 0.4 0.084 13.8 0.3 3.4 3 1 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain WD40 PF00400.27 GAP84348.1 - 1.5e-10 40.5 10.5 0.0065 16.3 0.0 8.0 8 1 0 8 8 8 3 WD domain, G-beta repeat PQQ_2 PF13360.1 GAP84348.1 - 2.7e-07 30.2 2.1 5.2e-05 22.8 0.1 2.8 2 1 1 3 3 3 2 PQQ-like domain PD40 PF07676.7 GAP84348.1 - 0.02 14.5 0.1 1.4 8.6 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.1 GAP84348.1 - 0.042 14.1 3.5 5.5 7.4 0.1 4.7 5 0 0 5 5 5 0 PQQ-like domain Rad4 PF03835.10 GAP84349.1 - 3.4e-16 58.9 3.1 6.7e-16 57.9 2.2 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 GAP84349.1 - 1.4e-14 54.2 1.9 3.2e-14 53.1 1.3 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Scramblase PF03803.10 GAP84352.1 - 0.018 14.1 0.3 4.2 6.3 0.0 2.2 2 0 0 2 2 2 0 Scramblase Zn_Tnp_IS1 PF03811.8 GAP84353.1 - 0.0013 18.1 1.8 0.34 10.4 0.2 2.4 2 0 0 2 2 2 2 InsA N-terminal domain Lar_restr_allev PF14354.1 GAP84353.1 - 0.053 13.8 4.4 0.28 11.4 3.0 2.0 1 1 0 1 1 1 0 Restriction alleviation protein Lar Cys_rich_KTR PF14205.1 GAP84353.1 - 0.091 12.2 0.6 1.1 8.7 0.1 2.3 2 0 0 2 2 2 0 Cysteine-rich KTR BRCT PF00533.21 GAP84354.1 - 0.16 12.1 0.0 0.62 10.2 0.0 1.9 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain MFS_1 PF07690.11 GAP84355.1 - 1.9e-45 155.1 56.1 1.3e-44 152.4 37.1 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAP84355.1 - 1.7e-16 59.5 16.0 2.5e-16 59.0 11.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAP84355.1 - 1.2e-15 57.0 4.8 1.2e-15 57.0 3.4 3.3 2 1 1 3 3 3 1 Sugar (and other) transporter LETM1 PF07766.8 GAP84357.1 - 3.7e-106 354.0 0.6 6.3e-106 353.3 0.4 1.4 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 GAP84357.1 - 2.2e-05 23.8 0.0 0.019 14.4 0.0 3.2 3 0 0 3 3 3 2 SAP domain Myosin_tail_1 PF01576.14 GAP84358.1 - 0.016 12.9 4.1 0.026 12.2 2.8 1.2 1 0 0 1 1 1 0 Myosin tail PG_binding_1 PF01471.13 GAP84358.1 - 0.1 12.5 0.0 13 5.8 0.0 2.8 2 0 0 2 2 2 0 Putative peptidoglycan binding domain Syntaxin-6_N PF09177.6 GAP84358.1 - 0.11 12.9 1.8 0.44 10.9 1.3 2.1 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Mem_trans PF03547.13 GAP84358.1 - 0.27 9.4 0.1 0.53 8.5 0.0 1.5 2 0 0 2 2 2 0 Membrane transport protein APG6 PF04111.7 GAP84358.1 - 2.3 7.1 8.9 0.71 8.8 4.1 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 GAP84358.1 - 2.6 7.7 16.1 0.046 13.4 6.1 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CLTH PF10607.4 GAP84359.1 - 3.6e-30 104.5 0.0 6e-30 103.8 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 GAP84359.1 - 9.1e-16 57.3 0.1 2e-15 56.2 0.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 GAP84359.1 - 5.9e-06 26.0 0.1 1.2e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAP84359.1 - 0.00014 21.7 0.1 0.00028 20.8 0.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 GAP84359.1 - 0.00021 20.5 0.0 0.00036 19.8 0.0 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.1 GAP84359.1 - 0.0036 16.9 0.1 0.0062 16.2 0.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 GAP84359.1 - 0.0041 16.7 0.1 0.0076 15.8 0.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAP84359.1 - 0.046 13.5 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 GAP84359.1 - 0.047 13.3 0.1 0.087 12.5 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SLEI_Leptospira PF07620.6 GAP84359.1 - 0.32 10.8 1.5 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 SLEI PetG PF02529.10 GAP84360.1 - 1.5 8.3 5.0 8.1 6.0 0.0 3.1 3 0 0 3 3 3 0 Cytochrome B6-F complex subunit 5 DUF2681 PF10883.3 GAP84360.1 - 3.6 7.8 5.9 1.4 9.1 0.1 3.3 4 1 1 5 5 5 0 Protein of unknown function (DUF2681) MpPF26 PF07666.6 GAP84360.1 - 6 6.7 17.0 0.12 12.3 4.2 3.0 2 2 0 2 2 2 0 M penetrans paralogue family 26 PPP4R2 PF09184.6 GAP84361.1 - 7.6e-10 38.8 0.1 6.2e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 PPP4R2 PsiA PF06952.6 GAP84361.1 - 0.13 11.2 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 PsiA protein SbcCD_C PF13558.1 GAP84362.1 - 3.9e-12 45.9 0.0 1.6e-11 43.9 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 GAP84362.1 - 2.5e-10 40.7 2.0 4e-05 23.7 0.0 3.5 4 0 0 4 4 4 2 AAA domain AAA_23 PF13476.1 GAP84362.1 - 2.2e-08 34.6 47.5 2.2e-08 34.6 32.9 6.7 1 1 1 2 2 2 1 AAA domain SMC_N PF02463.14 GAP84362.1 - 7.8e-06 25.2 0.0 7.8e-06 25.2 0.0 3.2 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_13 PF13166.1 GAP84362.1 - 7.2e-05 21.4 106.6 0.00053 18.6 0.0 7.5 2 1 4 7 7 7 5 AAA domain AAA_15 PF13175.1 GAP84362.1 - 0.0064 15.5 0.0 0.0026 16.8 10.0 5.1 3 2 1 5 5 5 2 AAA ATPase domain AAA_29 PF13555.1 GAP84362.1 - 0.007 15.8 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 GAP84362.1 - 0.098 12.9 0.0 0.098 12.9 0.0 7.7 4 2 0 4 4 4 0 ABC transporter GATA PF00320.22 GAP84363.1 - 1.1e-15 56.6 5.2 1.9e-15 55.9 3.6 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 GAP84363.1 - 1e-10 41.5 0.0 1.8e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 GAP84363.1 - 2.4e-08 34.3 0.0 5.9e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 GAP84363.1 - 3.3e-06 27.0 0.0 8.3e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 GAP84363.1 - 1.5e-05 24.7 0.1 4.1e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.1 GAP84363.1 - 0.00049 20.0 0.0 0.0013 18.6 0.0 1.7 2 0 0 2 2 2 1 PAS domain FmdE PF02663.9 GAP84363.1 - 0.03 14.2 0.0 0.072 12.9 0.0 1.6 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon TF_Zn_Ribbon PF08271.7 GAP84363.1 - 0.14 11.5 0.5 1 8.7 0.0 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Spc7 PF08317.6 GAP84363.1 - 0.16 10.6 0.7 0.46 9.1 0.4 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4428 PF14471.1 GAP84363.1 - 0.84 9.4 4.9 0.21 11.3 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) ECH PF00378.15 GAP84364.1 - 2.6e-33 115.1 0.0 4.3e-21 75.1 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family NYAP_N PF15439.1 GAP84365.1 - 0.032 13.4 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter HrpB1_HrpK PF09613.5 GAP84365.1 - 0.18 11.2 3.4 0.21 11.0 1.6 1.6 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) SGT1 PF07093.6 GAP84365.1 - 0.67 8.2 8.2 0.76 8.0 5.7 1.0 1 0 0 1 1 1 0 SGT1 protein FAD_binding_3 PF01494.14 GAP84366.1 - 4e-71 239.9 0.0 4.8e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAP84366.1 - 2.6e-06 26.6 0.1 4.5e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAP84366.1 - 3.4e-06 26.3 0.1 6.2e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 GAP84366.1 - 3.2e-05 23.8 0.1 8.8e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAP84366.1 - 8.5e-05 21.5 0.2 0.0019 17.1 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 GAP84366.1 - 0.00071 19.9 0.2 0.012 16.0 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP84366.1 - 0.0011 19.1 0.1 0.0025 17.9 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAP84366.1 - 0.0012 17.4 0.2 0.0049 15.3 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.9 GAP84366.1 - 0.0025 16.5 0.0 0.0046 15.6 0.0 1.5 2 0 0 2 2 2 1 Tryptophan halogenase TrkA_N PF02254.13 GAP84366.1 - 0.0032 17.4 0.0 0.027 14.4 0.0 2.5 3 0 0 3 3 2 1 TrkA-N domain Phe_hydrox_dim PF07976.7 GAP84366.1 - 0.0041 16.7 0.0 0.011 15.3 0.0 1.8 2 0 0 2 2 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.9 GAP84366.1 - 0.0074 16.1 2.2 0.026 14.4 0.5 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 GAP84366.1 - 0.029 13.7 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.2 GAP84366.1 - 0.03 13.4 0.6 0.068 12.2 0.4 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase ThiF PF00899.16 GAP84366.1 - 0.034 13.9 0.2 0.069 12.9 0.1 1.5 1 0 0 1 1 1 0 ThiF family NAD_binding_7 PF13241.1 GAP84366.1 - 0.036 14.3 0.0 0.083 13.1 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 GAP84366.1 - 0.047 12.6 0.2 0.077 11.8 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.13 GAP84366.1 - 0.097 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 GAP84366.1 - 0.11 11.3 0.2 0.16 10.7 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Transp_cyt_pur PF02133.10 GAP84367.1 - 8.6e-38 130.0 29.4 8.6e-38 130.0 20.4 1.8 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin F-box PF00646.28 GAP84368.1 - 0.0041 16.7 1.2 0.026 14.1 0.2 2.4 2 0 0 2 2 2 1 F-box domain RecR PF02132.10 GAP84368.1 - 2.1 7.8 5.6 1.8 8.0 0.0 2.7 2 1 0 2 2 2 0 RecR protein ADH_N PF08240.7 GAP84370.1 - 7.2e-25 86.8 0.6 1.1e-24 86.2 0.4 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAP84370.1 - 2.6e-05 23.7 0.0 4.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAP84370.1 - 0.025 15.4 0.1 0.039 14.8 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF2401 PF10287.4 GAP84371.1 - 3e-74 249.4 0.0 4.3e-74 248.9 0.0 1.2 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 GAP84371.1 - 4.7e-21 74.6 0.0 1.3e-20 73.2 0.0 1.8 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) DUF423 PF04241.10 GAP84372.1 - 6.6e-23 80.4 4.1 9.2e-23 79.9 2.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) YwiC PF14256.1 GAP84372.1 - 0.047 13.7 2.2 0.57 10.2 0.4 2.0 1 1 1 2 2 2 0 YwiC-like protein Lyase_1 PF00206.15 GAP84373.1 - 1.7e-86 290.2 0.0 2.2e-86 289.8 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 GAP84373.1 - 1.4e-25 89.1 0.1 2.8e-25 88.1 0.1 1.5 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal SHOCT PF09851.4 GAP84373.1 - 0.073 12.5 0.4 0.63 9.6 0.1 2.4 2 0 0 2 2 2 0 Short C-terminal domain Pribosyltran PF00156.22 GAP84374.1 - 3.1e-15 55.9 0.0 4.6e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_3 PF15610.1 GAP84374.1 - 0.021 13.7 0.0 0.029 13.2 0.0 1.1 1 0 0 1 1 1 0 PRTase ComF-like UPRTase PF14681.1 GAP84374.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase MFS_1_like PF12832.2 GAP84375.1 - 2.3e-18 65.7 0.4 1.5e-17 63.1 0.0 2.6 2 0 0 2 2 2 1 MFS_1 like family Cytochrom_B558a PF05038.8 GAP84375.1 - 0.039 13.5 0.8 0.089 12.4 0.3 1.8 1 1 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Zn_clus PF00172.13 GAP84376.1 - 8.6e-11 41.5 9.3 2.3e-10 40.2 6.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAP84376.1 - 4.4e-10 38.8 0.1 6.6e-10 38.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pex2_Pex12 PF04757.9 GAP84377.1 - 1.9e-39 135.4 2.0 3.3e-39 134.6 1.4 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 GAP84377.1 - 0.00015 21.5 4.3 0.0003 20.6 3.0 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Ferric_reduct PF01794.14 GAP84377.1 - 0.043 13.9 2.8 0.086 12.9 1.9 1.4 1 0 0 1 1 1 0 Ferric reductase like transmembrane component zf-C3HC4 PF00097.20 GAP84377.1 - 0.095 12.3 2.1 0.22 11.1 1.5 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAP84377.1 - 0.13 12.0 1.4 0.21 11.3 0.2 1.9 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 GAP84377.1 - 0.22 11.6 9.3 0.081 12.9 3.4 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) IBN_N PF03810.14 GAP84378.1 - 2.6e-12 46.4 0.1 5.1e-11 42.3 0.0 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 GAP84378.1 - 1.1e-05 25.4 3.1 0.00047 20.0 0.0 3.8 3 1 1 4 4 4 1 Exportin 1-like protein Cse1 PF08506.5 GAP84378.1 - 0.034 12.6 0.0 0.072 11.6 0.0 1.5 1 0 0 1 1 1 0 Cse1 PH_6 PF15406.1 GAP84379.1 - 5.9e-44 148.7 1.3 5.9e-44 148.7 0.9 3.0 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.24 GAP84379.1 - 0.047 13.8 0.0 0.14 12.3 0.0 1.9 1 0 0 1 1 1 0 PH domain tRNA-synt_2 PF00152.15 GAP84381.1 - 5e-82 275.3 0.0 6.1e-82 275.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 GAP84381.1 - 1.7e-10 40.5 0.0 4e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 GAP84381.1 - 5.7e-06 25.7 0.0 0.0019 17.4 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 GAP84381.1 - 0.01 15.4 0.0 0.78 9.3 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) zf-Tim10_DDP PF02953.10 GAP84382.1 - 7.9e-22 76.3 2.2 9.2e-22 76.1 1.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 GAP84382.1 - 0.022 14.1 1.9 0.026 13.9 1.3 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) BrkDBD PF09607.5 GAP84382.1 - 0.065 12.8 0.1 0.38 10.3 0.0 2.1 2 1 0 2 2 2 0 Brinker DNA-binding domain ADK PF00406.17 GAP84383.1 - 1.3e-38 132.2 0.0 7.9e-21 74.5 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 GAP84383.1 - 6.7e-14 51.2 0.0 1.1e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 GAP84383.1 - 2e-06 28.1 0.2 0.004 17.4 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_17 PF13207.1 GAP84383.1 - 0.0024 18.7 0.1 0.0058 17.4 0.0 1.8 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 GAP84383.1 - 0.008 16.0 0.5 0.059 13.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 GAP84383.1 - 0.07 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 GAP84383.1 - 0.11 11.6 0.0 0.25 10.3 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Glyco_hydro_76 PF03663.9 GAP84384.1 - 1.6e-19 70.5 0.2 8.7e-12 45.0 0.0 3.3 3 0 0 3 3 3 3 Glycosyl hydrolase family 76 ER_lumen_recept PF00810.13 GAP84386.1 - 2.7e-35 121.9 8.7 5.8e-35 120.9 6.0 1.6 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 GAP84386.1 - 0.078 12.5 0.1 0.078 12.5 0.1 3.0 3 0 0 3 3 3 0 PQ loop repeat DUF3816 PF12822.2 GAP84386.1 - 0.83 9.5 6.4 0.93 9.3 3.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3816) Sigma70_ner PF04546.8 GAP84386.1 - 5.2 6.6 15.0 0.19 11.2 6.3 1.5 2 0 0 2 2 2 0 Sigma-70, non-essential region CDC45 PF02724.9 GAP84386.1 - 9.2 4.1 7.5 13 3.6 5.2 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-GRF PF06839.7 GAP84387.1 - 0.11 12.4 1.5 0.2 11.5 1.0 1.6 1 1 0 1 1 1 0 GRF zinc finger A2L_zn_ribbon PF08792.5 GAP84387.1 - 0.31 10.5 1.4 3.7 7.1 0.1 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain Ribosomal_L37ae PF01780.14 GAP84388.1 - 1.5e-37 127.2 6.5 1.7e-37 127.1 4.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family A2L_zn_ribbon PF08792.5 GAP84388.1 - 0.015 14.7 1.1 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 GAP84388.1 - 0.031 14.0 5.9 0.05 13.4 4.1 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-Sec23_Sec24 PF04810.10 GAP84388.1 - 0.14 11.7 1.1 0.79 9.3 0.0 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Zn-ribbon_8 PF09723.5 GAP84388.1 - 0.16 11.9 2.7 0.27 11.2 0.3 2.1 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.1 GAP84388.1 - 0.16 12.3 0.6 5.9 7.3 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain zf-BED PF02892.10 GAP84388.1 - 0.44 10.3 2.7 3 7.6 1.9 2.1 1 1 0 1 1 1 0 BED zinc finger zf-C2H2_4 PF13894.1 GAP84388.1 - 0.61 10.5 2.4 14 6.3 0.7 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 GAP84388.1 - 3.6 8.1 5.7 35 5.0 1.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type CHCH PF06747.8 GAP84391.1 - 0.017 15.0 2.7 0.14 12.1 0.2 2.4 2 0 0 2 2 2 0 CHCH domain Ribosomal_S17 PF00366.15 GAP84392.1 - 7.8e-30 102.7 1.4 1.3e-29 101.9 1.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 Spc7_N PF15402.1 GAP84393.1 - 5e-246 819.0 48.6 6.6e-246 818.7 33.7 1.1 1 0 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 GAP84393.1 - 4.6e-119 396.8 3.7 1.2e-118 395.5 2.5 1.6 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 GAP84393.1 - 6.1e-18 64.2 0.1 1.3e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Spc7_C2 Mnd1 PF03962.10 GAP84393.1 - 0.043 13.4 18.3 0.069 12.8 2.0 3.5 2 1 1 3 3 3 0 Mnd1 family IncA PF04156.9 GAP84393.1 - 5.4 6.5 15.9 0.23 11.0 5.2 2.4 2 0 0 2 2 2 0 IncA protein Atg14 PF10186.4 GAP84395.1 - 3.1e-75 252.9 0.0 3.6e-75 252.7 0.0 1.0 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 AIP3 PF03915.8 GAP84395.1 - 0.00065 18.7 1.4 0.00094 18.1 1.0 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 DUF488 PF04343.8 GAP84396.1 - 0.19 12.1 6.4 0.58 10.5 1.4 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF488 DUF3807 PF12720.2 GAP84397.1 - 3.1e-34 118.6 3.8 5.8e-34 117.7 2.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3807) DUF1517 PF07466.6 GAP84397.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Pkinase PF00069.20 GAP84398.1 - 3.8e-61 206.4 0.0 4.4e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP84398.1 - 5.8e-21 74.7 0.0 8.1e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAP84398.1 - 3.5e-08 33.4 0.0 1.1e-05 25.2 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAP84398.1 - 0.012 15.2 0.1 0.035 13.6 0.1 1.8 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.1 GAP84398.1 - 0.037 12.9 0.0 0.057 12.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 GAP84398.1 - 0.055 12.5 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Scm3 PF10384.4 GAP84399.1 - 4e-11 42.2 0.5 8.2e-11 41.2 0.3 1.5 1 0 0 1 1 1 1 Centromere protein Scm3 FISNA PF14484.1 GAP84399.1 - 0.012 15.6 0.2 0.039 13.9 0.0 1.9 2 0 0 2 2 2 0 Fish-specific NACHT associated domain APG6 PF04111.7 GAP84400.1 - 1.1e-117 392.6 0.0 1.3e-117 392.3 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 zf-C4H2 PF10146.4 GAP84400.1 - 0.072 13.1 6.4 0.14 12.1 4.5 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein bZIP_2 PF07716.10 GAP84400.1 - 0.24 11.2 8.6 0.54 10.1 6.0 1.5 1 0 0 1 1 1 0 Basic region leucine zipper V_ATPase_I PF01496.14 GAP84400.1 - 0.55 8.0 5.5 0.74 7.5 3.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 GAP84400.1 - 0.7 10.2 4.9 1.4 9.2 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) IncA PF04156.9 GAP84400.1 - 2.6 7.6 12.9 4 6.9 8.9 1.2 1 0 0 1 1 1 0 IncA protein OmpH PF03938.9 GAP84400.1 - 8.5 6.2 10.9 14 5.6 7.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HET PF06985.6 GAP84401.1 - 1.1e-19 70.9 0.0 2.4e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA PF00004.24 GAP84401.1 - 0.0012 19.0 0.0 0.0037 17.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) COesterase PF00135.23 GAP84403.1 - 2.8e-59 201.2 0.0 3.3e-59 201.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAP84403.1 - 0.066 12.7 0.1 0.2 11.1 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAP84404.1 - 2.8e-19 69.9 0.1 3.4e-19 69.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP84404.1 - 2.1e-10 40.5 0.0 2.4e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 GAP84404.1 - 2.7e-05 23.8 0.0 3.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 GAP84404.1 - 0.017 15.3 0.0 0.064 13.4 0.0 1.9 2 1 0 2 2 2 0 Thioesterase domain PGAP1 PF07819.8 GAP84404.1 - 0.027 14.0 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF2305 PF10230.4 GAP84404.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Eno-Rase_NADH_b PF12242.3 GAP84404.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Peptidase_S8 PF00082.17 GAP84405.1 - 2.7e-43 148.1 17.0 4.2e-43 147.5 11.8 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 GAP84405.1 - 5.3e-18 65.3 0.2 9.6e-18 64.5 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF3176 PF11374.3 GAP84406.1 - 7.2e-32 109.5 3.2 1.5e-31 108.5 2.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Glyco_hydro_18 PF00704.23 GAP84408.1 - 8.4e-49 166.8 0.0 1e-48 166.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 WD40 PF00400.27 GAP84409.1 - 0.0028 17.4 9.3 0.015 15.2 0.5 4.4 5 0 0 5 5 5 1 WD domain, G-beta repeat Nop14 PF04147.7 GAP84409.1 - 0.81 7.5 17.0 1 7.1 11.8 1.1 1 0 0 1 1 1 0 Nop14-like family SURF2 PF05477.6 GAP84409.1 - 2.5 7.1 14.8 3.7 6.6 10.3 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CDC45 PF02724.9 GAP84409.1 - 2.9 5.8 17.3 4.1 5.3 12.0 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 GAP84409.1 - 8.3 5.5 24.4 13 4.9 16.9 1.2 1 0 0 1 1 1 0 SDA1 Inositol_P PF00459.20 GAP84410.1 - 3e-78 262.8 0.0 3.6e-78 262.5 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family Ant_C PF05586.6 GAP84410.1 - 0.08 13.4 0.1 0.14 12.6 0.1 1.3 1 0 0 1 1 1 0 Anthrax receptor C-terminus region Shikimate_dh_N PF08501.6 GAP84412.1 - 2.1e-20 72.5 0.0 4.4e-20 71.5 0.0 1.5 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 GAP84412.1 - 1.2e-10 41.5 0.1 1.9e-10 40.9 0.1 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.19 GAP84413.1 - 6.9e-120 400.6 20.9 1.2e-119 399.9 14.5 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP84413.1 - 1.8e-22 79.5 38.8 3.6e-22 78.5 24.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily AP_endonuc_2 PF01261.19 GAP84414.1 - 1.5e-28 99.5 0.7 2.3e-28 98.9 0.5 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Fungal_trans PF04082.13 GAP84415.1 - 4.8e-19 68.2 0.1 7.9e-19 67.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP84415.1 - 0.00013 21.7 11.9 0.00025 20.9 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_I PF01487.10 GAP84416.1 - 2.1e-40 138.7 0.0 3.3e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 GAP84416.1 - 4.4e-21 74.7 0.0 9.6e-21 73.6 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 GAP84416.1 - 1.5e-16 60.7 0.0 3.3e-16 59.5 0.0 1.5 2 0 0 2 2 2 1 Shikimate kinase Shikimate_DH PF01488.15 GAP84416.1 - 6.3e-10 39.2 0.1 1.2e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.1 GAP84416.1 - 0.0065 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAP84416.1 - 0.014 16.2 0.0 0.031 15.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain F420_oxidored PF03807.12 GAP84416.1 - 0.042 14.2 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AAA_18 PF13238.1 GAP84416.1 - 0.099 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 GAP84416.1 - 0.13 11.7 0.2 0.32 10.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 GAP84416.1 - 0.16 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 GAP84416.1 - 0.29 10.2 1.6 0.26 10.3 0.1 1.6 2 0 0 2 2 2 0 Zeta toxin CTD PF12815.2 GAP84417.1 - 2.1e-27 95.9 64.3 1.2e-14 54.7 9.2 5.2 3 1 3 6 6 6 3 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.8 GAP84417.1 - 3e-22 78.1 0.0 5.1e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 GAP84417.1 - 1.1e-10 42.0 10.0 1.1e-10 42.0 6.9 3.7 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 GAP84417.1 - 2.7e-05 23.6 13.0 0.0031 17.1 0.1 5.7 6 0 0 6 6 6 2 KOW motif WD40 PF00400.27 GAP84418.1 - 1.1e-21 75.8 9.3 2e-08 33.8 0.0 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Rho_RNA_bind PF07497.7 GAP84418.1 - 0.13 11.9 0.1 2.7 7.7 0.0 2.5 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain CTP_transf_2 PF01467.21 GAP84419.1 - 0.00095 19.2 1.2 0.0091 16.0 0.9 2.6 1 1 0 1 1 1 1 Cytidylyltransferase DOCK-C2 PF14429.1 GAP84419.1 - 0.047 13.3 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins adh_short PF00106.20 GAP84420.1 - 6e-23 81.5 1.3 7.9e-23 81.2 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP84420.1 - 1.5e-18 67.4 0.0 1.9e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP84420.1 - 1.3e-12 47.7 0.1 1.7e-12 47.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAP84420.1 - 5.1e-07 29.3 0.0 6.6e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAP84420.1 - 5.8e-05 21.9 0.0 8.3e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 GAP84420.1 - 0.016 14.0 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 GAP84420.1 - 0.047 13.8 0.4 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF3994 PF13159.1 GAP84422.1 - 0.033 14.4 0.4 0.16 12.2 0.3 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3994) Seryl_tRNA_N PF02403.17 GAP84422.1 - 0.56 10.2 9.1 0.32 11.0 3.7 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4140 PF13600.1 GAP84422.1 - 0.93 9.9 8.2 40 4.7 0.0 4.1 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF3287 PF11690.3 GAP84422.1 - 8.8 6.4 8.4 1.5 8.8 1.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3287) DUF972 PF06156.8 GAP84422.1 - 9.4 6.6 7.4 3.5 8.0 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF972) DUF1748 PF08520.5 GAP84423.1 - 7.7e-33 111.9 0.1 9.3e-33 111.7 0.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) PK PF00224.16 GAP84424.1 - 2.7e-167 555.7 2.8 3.4e-167 555.3 2.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 GAP84424.1 - 1.8e-29 101.6 0.0 4.7e-29 100.3 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 GAP84424.1 - 9.6e-05 21.3 1.1 0.00025 20.0 0.3 1.9 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Ank PF00023.25 GAP84425.1 - 5.8e-20 70.0 0.5 0.00048 19.7 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_2 PF12796.2 GAP84425.1 - 5.9e-18 64.9 0.0 1.3e-07 31.8 0.0 4.3 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAP84425.1 - 3.1e-13 49.8 0.6 0.018 15.5 0.0 6.5 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP84425.1 - 7.4e-13 47.3 0.2 0.0026 17.8 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 GAP84425.1 - 9.4e-09 35.2 0.0 0.13 12.6 0.0 4.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) F-box-like PF12937.2 GAP84425.1 - 1e-07 31.5 0.2 3.4e-07 29.8 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAP84425.1 - 4.6e-07 29.3 0.4 1.5e-06 27.7 0.1 2.0 2 0 0 2 2 2 1 F-box domain LCM PF04072.9 GAP84426.1 - 5.2e-41 140.2 0.0 6.6e-41 139.8 0.0 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase PRNT PF15174.1 GAP84426.1 - 0.095 12.3 0.1 0.27 10.9 0.1 1.7 1 0 0 1 1 1 0 Prion-related protein testis-specific MFS_1 PF07690.11 GAP84427.1 - 2.4e-48 164.6 29.6 2.4e-48 164.6 20.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP84427.1 - 2.2e-13 49.6 13.4 2.2e-13 49.6 9.3 2.8 2 2 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 GAP84427.1 - 6.2e-06 24.6 0.3 6.2e-06 24.6 0.2 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2269 PF10027.4 GAP84427.1 - 0.12 12.1 8.4 2.4 7.9 0.1 2.6 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) Fungal_trans PF04082.13 GAP84428.1 - 2.1e-18 66.1 0.0 4.9e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP84428.1 - 3.6e-05 23.5 10.1 6.5e-05 22.7 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_13 PF13166.1 GAP84428.1 - 0.33 9.3 0.0 0.54 8.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Aldo_ket_red PF00248.16 GAP84429.1 - 1.2e-40 139.1 0.0 1.5e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Integrase_Zn PF02022.14 GAP84429.1 - 0.0083 15.5 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Integrase Zinc binding domain MFS_1 PF07690.11 GAP84430.1 - 2.1e-31 108.9 32.5 2.1e-31 108.9 22.5 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily MMPL PF03176.10 GAP84430.1 - 4.4 5.9 10.5 0.024 13.3 0.5 2.2 3 0 0 3 3 3 0 MMPL family Polysacc_synt_4 PF04669.8 GAP84431.1 - 1.8e-25 89.4 1.3 1e-24 86.9 0.9 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis ABC_membrane PF00664.18 GAP84432.1 - 1.1e-64 218.5 30.3 8.2e-39 133.6 9.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAP84432.1 - 8.5e-62 207.4 0.0 1.7e-31 109.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 GAP84432.1 - 3.4e-14 53.5 0.1 0.0097 15.8 0.0 4.7 5 0 0 5 5 5 3 AAA domain SMC_N PF02463.14 GAP84432.1 - 5.1e-14 52.0 1.0 1.6e-05 24.2 0.0 5.2 5 0 0 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAP84432.1 - 5.2e-08 32.2 0.3 0.0097 15.4 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 GAP84432.1 - 7.3e-08 33.2 0.1 0.02 15.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 GAP84432.1 - 3.3e-07 29.2 0.1 3.3e-05 22.6 0.0 3.3 4 0 0 4 4 4 1 Predicted ATPase of the ABC class DUF258 PF03193.11 GAP84432.1 - 1.2e-06 27.8 0.0 0.017 14.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 GAP84432.1 - 4e-06 26.9 1.8 0.11 12.4 0.3 3.8 3 1 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.1 GAP84432.1 - 1.2e-05 25.7 0.1 0.0068 16.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAP84432.1 - 2e-05 24.8 0.1 0.14 12.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 GAP84432.1 - 4.4e-05 22.9 0.0 0.36 10.2 0.0 3.2 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.1 GAP84432.1 - 0.00028 21.0 1.9 1.4 9.0 0.1 4.1 3 1 0 3 3 3 1 AAA domain AAA_10 PF12846.2 GAP84432.1 - 0.00028 20.4 1.6 0.62 9.4 0.0 3.1 3 0 0 3 3 3 2 AAA-like domain AAA PF00004.24 GAP84432.1 - 0.00044 20.4 0.1 0.19 11.9 0.0 3.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 GAP84432.1 - 0.003 17.4 0.1 4.1 7.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 GAP84432.1 - 0.003 17.2 0.3 4.2 7.0 0.0 3.8 5 0 0 5 5 4 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 GAP84432.1 - 0.0047 16.3 0.1 3.2 7.1 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein SbcCD_C PF13558.1 GAP84432.1 - 0.0049 16.7 0.3 0.54 10.2 0.0 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 GAP84432.1 - 0.0097 16.0 0.0 4.4 7.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase MMR_HSR1 PF01926.18 GAP84432.1 - 0.011 15.7 1.1 1.9 8.4 0.0 2.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.7 GAP84432.1 - 0.04 13.0 0.0 11 5.0 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin FtsK_SpoIIIE PF01580.13 GAP84432.1 - 0.045 13.2 0.1 11 5.4 0.0 3.3 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF87 PF01935.12 GAP84432.1 - 0.053 13.3 2.2 5.2 6.8 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_13 PF13166.1 GAP84432.1 - 0.064 11.7 0.1 4 5.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.17 GAP84432.1 - 0.071 11.9 0.2 2.9 6.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.1 GAP84432.1 - 0.083 12.7 0.2 4.7 7.1 0.0 3.6 4 0 0 4 4 4 0 AAA domain MobB PF03205.9 GAP84432.1 - 0.19 11.4 0.5 23 4.6 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B KaiC PF06745.8 GAP84432.1 - 0.81 8.7 2.4 34 3.4 0.1 3.1 3 0 0 3 3 3 0 KaiC Glyco_hydro_61 PF03443.9 GAP84433.1 - 7e-44 150.2 0.0 7.9e-44 150.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NmrA PF05368.8 GAP84435.1 - 3e-24 85.5 0.0 4e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAP84435.1 - 1.6e-18 67.3 1.3 2.2e-18 66.8 0.9 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 GAP84435.1 - 6.4e-05 22.9 1.8 0.00016 21.6 1.2 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 GAP84435.1 - 0.00058 18.9 0.8 0.00097 18.2 0.3 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase Epimerase PF01370.16 GAP84435.1 - 0.00063 19.2 0.7 0.0012 18.3 0.5 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAP84435.1 - 0.002 16.9 0.2 0.0043 15.7 0.1 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 GAP84435.1 - 0.015 14.1 0.2 0.023 13.5 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DapB_N PF01113.15 GAP84435.1 - 0.024 14.5 0.5 0.04 13.8 0.4 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 GAP84435.1 - 0.044 14.0 0.5 0.074 13.3 0.4 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 GAP84435.1 - 0.047 14.1 1.1 0.11 12.8 0.7 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 GAP84435.1 - 0.061 12.9 2.9 0.16 11.6 2.0 1.8 1 1 0 1 1 1 0 KR domain DFP PF04127.10 GAP84435.1 - 0.36 10.4 3.5 0.62 9.6 2.4 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Glyco_trans_4_4 PF13579.1 GAP84435.1 - 1.3 9.1 8.2 0.66 10.1 3.7 2.0 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain Tyrosinase PF00264.15 GAP84436.1 - 9.7e-33 114.1 4.0 1.5e-32 113.5 2.8 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase MutS_V PF00488.16 GAP84438.1 - 4e-79 265.3 0.1 6.5e-79 264.6 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 GAP84438.1 - 1.2e-52 178.7 0.2 2.1e-52 177.8 0.2 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 GAP84438.1 - 4.5e-31 107.2 0.1 1e-30 106.0 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 GAP84438.1 - 1.1e-16 61.1 0.0 3.1e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 GAP84438.1 - 4.8e-12 45.9 0.4 1.3e-11 44.4 0.3 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.1 GAP84438.1 - 0.0062 16.8 0.1 0.0062 16.8 0.1 3.0 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.1 GAP84438.1 - 0.012 15.0 0.1 0.036 13.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 GAP84438.1 - 0.081 12.8 0.2 0.081 12.8 0.2 2.1 2 0 0 2 2 2 0 AAA domain UbiA PF01040.13 GAP84439.1 - 7.2e-29 100.7 21.5 1e-28 100.2 14.9 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Mito_carr PF00153.22 GAP84439.1 - 0.016 14.8 0.3 2.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial carrier protein Myb_DNA-bind_6 PF13921.1 GAP84440.1 - 0.00013 21.9 1.2 0.00039 20.4 0.8 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Orbi_NS1 PF01718.11 GAP84440.1 - 0.013 13.5 0.2 0.019 13.0 0.1 1.1 1 0 0 1 1 1 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein Tmemb_cc2 PF10267.4 GAP84440.1 - 6.1 5.3 6.8 9.2 4.7 4.7 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Sugar_tr PF00083.19 GAP84441.1 - 5e-116 387.9 23.8 6e-116 387.6 16.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP84441.1 - 2.9e-26 92.0 53.8 6.4e-24 84.3 19.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Lysis_S PF04971.7 GAP84441.1 - 0.13 11.9 2.7 0.17 11.5 0.2 2.3 2 0 0 2 2 2 0 Lysis protein S mRNA_triPase PF02940.10 GAP84443.1 - 2.1e-46 158.3 1.6 2.2e-46 158.3 0.0 1.8 2 0 0 2 2 2 1 mRNA capping enzyme, beta chain Ycf1 PF05758.7 GAP84443.1 - 0.027 12.2 4.3 0.036 11.8 3.0 1.1 1 0 0 1 1 1 0 Ycf1 AAA_23 PF13476.1 GAP84443.1 - 1.3 9.3 16.1 2.1 8.6 11.2 1.3 1 0 0 1 1 1 0 AAA domain PC_rep PF01851.17 GAP84444.1 - 7e-37 123.6 22.1 2.2e-08 33.8 0.0 9.5 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 GAP84444.1 - 6.5e-17 61.6 0.1 4.5e-12 46.0 0.0 4.6 2 1 2 5 5 5 2 HEAT repeats HEAT PF02985.17 GAP84444.1 - 3.4e-09 36.0 0.1 0.28 11.3 0.0 5.9 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 GAP84444.1 - 7.2e-08 32.6 0.0 8e-05 23.0 0.0 4.2 3 0 0 3 3 3 1 HEAT-like repeat Codanin-1_C PF15296.1 GAP84444.1 - 0.004 17.0 0.1 0.011 15.5 0.1 1.7 1 0 0 1 1 1 1 Codanin-1 C-terminus Xan_ur_permease PF00860.15 GAP84445.1 - 1.2e-62 211.6 35.7 2.7e-61 207.1 24.8 2.1 1 1 0 1 1 1 1 Permease family SR-25 PF10500.4 GAP84446.1 - 0.0019 17.7 10.5 0.0022 17.5 7.3 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF3752 PF12572.3 GAP84446.1 - 0.02 15.0 10.3 0.023 14.7 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) CAF-1_p150 PF11600.3 GAP84446.1 - 0.041 13.2 18.7 0.047 13.0 13.0 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FAM176 PF14851.1 GAP84446.1 - 0.051 13.2 2.5 0.057 13.0 1.7 1.0 1 0 0 1 1 1 0 FAM176 family YqfQ PF14181.1 GAP84446.1 - 0.1 12.6 7.8 0.1 12.6 5.4 1.0 1 0 0 1 1 1 0 YqfQ-like protein DUF1764 PF08576.5 GAP84446.1 - 0.12 13.2 6.3 0.13 13.0 4.3 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF4355 PF14265.1 GAP84446.1 - 0.13 12.2 17.2 0.15 12.0 12.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) MotA_ExbB PF01618.11 GAP84446.1 - 0.16 11.6 0.5 0.18 11.4 0.4 1.1 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family Activator_LAG-3 PF11498.3 GAP84446.1 - 0.22 10.2 4.3 0.23 10.1 3.0 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 NARP1 PF12569.3 GAP84446.1 - 0.31 9.7 13.1 0.32 9.6 9.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Pox_Ag35 PF03286.9 GAP84446.1 - 0.37 10.2 7.9 0.39 10.1 5.5 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2992 PF11208.3 GAP84446.1 - 0.45 10.4 15.9 0.54 10.1 11.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DUF3365 PF11845.3 GAP84446.1 - 0.63 9.8 3.1 0.72 9.6 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) Bud13 PF09736.4 GAP84446.1 - 0.71 10.1 10.1 0.82 9.9 7.0 1.0 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF607 PF04678.8 GAP84446.1 - 0.9 9.4 3.6 0.96 9.3 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF607 DUF4140 PF13600.1 GAP84446.1 - 1.1 9.6 6.9 1.3 9.5 4.8 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) AIF_C PF14721.1 GAP84446.1 - 1.3 9.2 3.5 1.5 9.1 2.4 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3451 PF11933.3 GAP84446.1 - 1.8 8.3 9.7 2 8.1 6.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3451) Borrelia_P83 PF05262.6 GAP84446.1 - 1.8 6.7 12.3 2 6.5 8.5 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Cid2 PF09774.4 GAP84446.1 - 1.9 8.5 8.0 2.2 8.3 5.5 1.0 1 0 0 1 1 1 0 Caffeine-induced death protein 2 DUF1510 PF07423.6 GAP84446.1 - 2 7.7 10.3 2.2 7.6 7.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3682 PF12446.3 GAP84446.1 - 2 8.7 8.4 2.6 8.3 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Mitofilin PF09731.4 GAP84446.1 - 2.1 6.8 12.2 2.3 6.7 8.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein APG6 PF04111.7 GAP84446.1 - 2.2 7.2 9.5 2.3 7.1 6.6 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Peptidase_S49_N PF08496.5 GAP84446.1 - 2.3 7.9 9.2 3.1 7.5 6.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal G0-G1_switch_2 PF15103.1 GAP84446.1 - 2.5 8.3 6.2 3 8.1 4.3 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 G-alpha PF00503.15 GAP84446.1 - 2.9 6.5 5.8 2.8 6.5 4.0 1.0 1 0 0 1 1 1 0 G-protein alpha subunit RR_TM4-6 PF06459.7 GAP84446.1 - 3.2 7.5 9.7 3.5 7.4 6.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.7 GAP84446.1 - 3.7 7.4 6.8 4 7.3 4.7 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family GvpL_GvpF PF06386.6 GAP84446.1 - 4.4 6.8 8.0 4.6 6.7 5.5 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF2228 PF10228.4 GAP84446.1 - 4.7 6.6 6.0 5.4 6.4 4.2 1.0 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) DDHD PF02862.12 GAP84446.1 - 5.2 6.8 7.6 5.7 6.6 5.3 1.0 1 0 0 1 1 1 0 DDHD domain Sec62 PF03839.11 GAP84446.1 - 5.4 6.3 9.2 6.3 6.1 6.4 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 Ycf1 PF05758.7 GAP84446.1 - 5.9 4.4 7.5 6.2 4.4 5.2 1.0 1 0 0 1 1 1 0 Ycf1 DUF3464 PF11947.3 GAP84446.1 - 6.7 6.1 7.6 7.7 5.9 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) eIF3_subunit PF08597.5 GAP84446.1 - 6.9 6.1 17.1 8.5 5.8 11.9 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF4337 PF14235.1 GAP84446.1 - 7.2 6.4 10.3 8 6.2 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) NinG PF05766.7 GAP84446.1 - 7.2 6.3 10.3 8.3 6.1 7.1 1.0 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein DUF4582 PF15189.1 GAP84446.1 - 7.7 5.7 9.1 9.2 5.4 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4582) Ribosomal_S19 PF00203.16 GAP84447.1 - 4.2e-30 103.1 0.0 6e-30 102.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 DUF3619 PF12279.3 GAP84447.1 - 0.064 13.3 0.1 0.086 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Pedibin PF08182.6 GAP84448.1 - 0.0099 15.3 0.6 0.026 14.0 0.4 1.8 1 0 0 1 1 1 1 Pedibin/Hym-346 family TMF_DNA_bd PF12329.3 GAP84448.1 - 0.021 14.6 6.0 0.034 13.9 4.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Siah-Interact_N PF09032.6 GAP84448.1 - 0.031 14.3 0.7 0.053 13.5 0.5 1.4 1 0 0 1 1 1 0 Siah interacting protein, N terminal Glyco_hydro_61 PF03443.9 GAP84449.1 - 7.2e-49 166.5 0.0 1.1e-48 165.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_31 PF01055.21 GAP84450.1 - 1.1e-162 541.8 5.0 1.4e-162 541.5 3.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 zf-CCCH PF00642.19 GAP84451.1 - 8.3e-13 47.6 15.2 2.2e-06 27.2 0.2 3.3 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 GAP84451.1 - 0.012 15.5 0.2 0.012 15.5 0.2 3.4 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type LRV_FeS PF05484.6 GAP84451.1 - 4 7.0 7.0 4.3 7.0 0.1 3.0 2 1 1 3 3 3 0 LRV protein FeS4 cluster GRP PF07172.6 GAP84451.1 - 5.1 7.6 25.2 7.9 7.0 17.4 1.4 1 0 0 1 1 1 0 Glycine rich protein family DUF1776 PF08643.5 GAP84452.1 - 4.1e-104 347.9 0.0 4.9e-104 347.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Oxidored_FMN PF00724.15 GAP84453.1 - 6.9e-94 314.6 0.0 8e-94 314.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Toxin_27 PF08099.6 GAP84453.1 - 0.057 13.3 0.9 0.1 12.5 0.7 1.4 1 0 0 1 1 1 0 Scorpion calcine family Kinesin PF00225.18 GAP84454.1 - 7.1e-48 163.0 0.0 2.6e-24 85.5 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain AAA_16 PF13191.1 GAP84454.1 - 0.19 11.7 2.5 1.8 8.5 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain p450 PF00067.17 GAP84455.1 - 9.5e-63 212.3 0.0 1.6e-62 211.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 GAP84456.1 - 2.4e-32 112.0 26.3 3.3e-32 111.5 18.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Neurensin PF14927.1 GAP84456.1 - 0.1 12.0 1.8 4.4 6.6 0.0 2.8 3 0 0 3 3 3 0 Neurensin BATS PF06968.8 GAP84457.1 - 1.2e-29 101.9 0.0 3.4e-29 100.5 0.0 1.8 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 GAP84457.1 - 4.5e-15 56.2 0.1 7.5e-15 55.4 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Aminotran_1_2 PF00155.16 GAP84458.1 - 5.3e-20 71.6 0.0 7.7e-20 71.1 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.16 GAP84459.1 - 6.2e-43 146.9 0.0 8.6e-24 84.0 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 GAP84459.1 - 4e-16 59.2 0.0 8.9e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Peptidase_M35 PF02102.10 GAP84460.1 - 7.9e-81 271.4 22.4 9.6e-81 271.2 15.5 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 GAP84460.1 - 8.5e-10 39.3 3.5 1.2e-09 38.7 2.1 1.5 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase Apolipoprotein PF01442.13 GAP84461.1 - 0.0042 16.6 0.1 0.0046 16.5 0.0 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain HCR PF07111.7 GAP84461.1 - 0.036 12.0 0.1 0.039 11.9 0.1 1.1 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) Sds3 PF08598.6 GAP84461.1 - 0.041 13.4 0.2 0.059 12.8 0.2 1.3 1 0 0 1 1 1 0 Sds3-like Baculo_PEP_C PF04513.7 GAP84461.1 - 0.049 13.4 0.4 0.11 12.2 0.1 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HSCB_C PF07743.8 GAP84461.1 - 0.077 13.4 3.3 0.29 11.6 1.7 2.0 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain IFP_35_N PF07334.8 GAP84461.1 - 0.085 12.8 0.2 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus NAAA-beta PF15508.1 GAP84461.1 - 0.14 12.5 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase XhlA PF10779.4 GAP84461.1 - 0.14 12.1 0.6 0.26 11.2 0.4 1.5 1 0 0 1 1 1 0 Haemolysin XhlA HalX PF08663.5 GAP84461.1 - 0.94 9.5 6.1 3.8 7.5 0.6 2.6 2 1 1 3 3 3 0 HalX domain GMC_oxred_N PF00732.14 GAP84463.1 - 1.2e-52 178.9 0.0 1.6e-52 178.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAP84463.1 - 2.3e-30 105.7 0.1 4.1e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAP84463.1 - 3.4e-11 42.6 0.5 2.4e-10 39.8 0.3 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 GAP84463.1 - 5.2e-09 35.4 0.3 0.0013 17.6 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 GAP84463.1 - 7.2e-08 31.6 0.1 0.0011 17.9 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 GAP84463.1 - 2.4e-06 26.2 0.0 0.0024 16.4 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.1 GAP84463.1 - 2.4e-05 24.2 0.0 6.9e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 GAP84463.1 - 5.3e-05 22.4 0.4 0.0021 17.2 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAP84463.1 - 5.5e-05 23.1 0.0 0.0042 16.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAP84463.1 - 0.00014 20.8 0.1 0.00022 20.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 GAP84463.1 - 0.0046 17.0 0.0 0.055 13.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAP84463.1 - 0.011 15.5 0.1 0.36 10.5 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 GAP84463.1 - 0.032 12.8 0.0 0.046 12.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.22 GAP84463.1 - 0.061 13.7 0.1 0.23 11.8 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAP84463.1 - 0.082 11.9 0.1 0.23 10.5 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Abhydrolase_6 PF12697.2 GAP84465.1 - 1.4e-28 100.3 0.2 1.8e-28 99.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP84465.1 - 1.8e-17 63.6 0.2 3.4e-15 56.2 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP84465.1 - 3.8e-15 55.8 0.0 6.5e-15 55.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.7 GAP84465.1 - 6.8e-06 25.1 0.0 8.7e-06 24.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Hydrolase_4 PF12146.3 GAP84465.1 - 3.6e-05 23.5 0.0 7.1e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 GAP84465.1 - 0.00032 19.2 0.0 0.00048 18.6 0.0 1.2 1 0 0 1 1 1 1 Ndr family UPF0227 PF05728.7 GAP84465.1 - 0.0068 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Ser_hydrolase PF06821.8 GAP84465.1 - 0.021 14.4 0.0 0.049 13.2 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase PGAP1 PF07819.8 GAP84465.1 - 0.039 13.5 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF915 PF06028.6 GAP84465.1 - 0.062 12.3 0.1 0.08 12.0 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) PAF-AH_p_II PF03403.8 GAP84465.1 - 0.077 11.2 0.0 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Lipase_3 PF01764.20 GAP84465.1 - 0.083 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Pex24p PF06398.6 GAP84466.1 - 0.031 13.0 0.4 0.083 11.6 0.0 1.8 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin DUF1675 PF07897.6 GAP84466.1 - 4.4 7.0 21.5 6.7 6.4 14.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) TPR_12 PF13424.1 GAP84467.1 - 2e-27 94.9 18.9 8e-11 41.7 0.0 6.0 3 1 2 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 GAP84467.1 - 2e-24 84.7 21.8 2.7e-08 33.4 0.0 7.2 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_11 PF13414.1 GAP84467.1 - 5.8e-11 41.8 8.3 0.0045 16.6 0.6 4.6 4 0 0 4 4 4 3 TPR repeat TPR_7 PF13176.1 GAP84467.1 - 1.2e-07 31.0 16.5 0.18 11.6 0.0 6.5 6 0 0 6 6 5 3 Tetratricopeptide repeat NB-ARC PF00931.17 GAP84467.1 - 1.8e-07 30.2 0.0 3.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 GAP84467.1 - 1.6e-06 28.2 0.0 8e-06 26.0 0.0 2.2 2 0 0 2 2 1 1 AAA domain TPR_14 PF13428.1 GAP84467.1 - 1.9e-06 27.9 12.9 0.081 13.6 0.1 6.8 3 2 4 7 7 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAP84467.1 - 3.7e-05 23.3 16.8 5.9 7.0 1.1 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat Abhydrolase_5 PF12695.2 GAP84467.1 - 0.0002 21.1 0.1 0.0025 17.5 0.0 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP84467.1 - 0.00043 20.2 0.2 0.0015 18.4 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family NACHT PF05729.7 GAP84467.1 - 0.001 18.7 0.0 0.0093 15.6 0.0 2.4 2 0 0 2 2 2 1 NACHT domain PGAP1 PF07819.8 GAP84467.1 - 0.0017 18.0 0.0 0.0042 16.7 0.0 1.6 2 0 0 2 2 1 1 PGAP1-like protein TPR_19 PF14559.1 GAP84467.1 - 0.0029 17.8 9.2 0.06 13.6 0.0 5.0 2 1 3 5 5 5 2 Tetratricopeptide repeat AAA_16 PF13191.1 GAP84467.1 - 0.0052 16.8 0.0 0.048 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 GAP84467.1 - 0.0081 16.4 0.0 0.059 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain TPR_1 PF00515.23 GAP84467.1 - 0.011 15.3 12.9 3.6 7.3 0.3 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 GAP84467.1 - 0.02 15.2 12.9 20 5.9 0.0 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAP84467.1 - 0.045 13.9 1.5 1.2e+02 3.3 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat IstB_IS21 PF01695.12 GAP84467.1 - 0.053 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein PPR PF01535.15 GAP84467.1 - 0.077 13.0 0.5 15 5.7 0.0 3.5 3 0 0 3 3 3 0 PPR repeat Abhydrolase_1 PF00561.15 GAP84467.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.6 2 0 0 2 2 1 0 alpha/beta hydrolase fold TPR_16 PF13432.1 GAP84467.1 - 0.31 11.7 24.5 0.12 13.1 1.7 5.9 3 2 4 7 7 7 0 Tetratricopeptide repeat DUF1657 PF07870.6 GAP84467.1 - 0.34 10.6 4.5 0.32 10.7 0.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1657) TPR_9 PF13371.1 GAP84467.1 - 3 7.7 15.6 1.7 8.5 0.1 5.1 3 2 2 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 GAP84467.1 - 4.1 7.3 10.0 2 8.3 0.5 3.6 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain HET PF06985.6 GAP84468.1 - 1.9e-20 73.4 1.6 5e-20 72.0 1.1 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AMP-binding PF00501.23 GAP84469.1 - 9.4e-66 221.9 0.0 1.2e-65 221.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAP84469.1 - 0.00058 20.7 0.1 0.0013 19.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3176 PF11374.3 GAP84470.1 - 1.7e-28 98.7 0.4 2.8e-28 98.0 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) FHA PF00498.21 GAP84471.1 - 3.3e-17 62.3 0.1 8.6e-17 61.0 0.0 1.8 1 0 0 1 1 1 1 FHA domain Myosin_tail_1 PF01576.14 GAP84471.1 - 0.00089 17.1 5.1 0.00089 17.1 3.6 2.2 2 0 0 2 2 2 1 Myosin tail Med9 PF07544.8 GAP84471.1 - 0.036 13.8 3.8 0.31 10.7 0.1 3.3 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 YlqD PF11068.3 GAP84471.1 - 4.6 7.2 16.2 1.1 9.3 4.5 2.5 2 0 0 2 2 2 0 YlqD protein Cu-oxidase_3 PF07732.10 GAP84472.1 - 1.1e-42 144.4 8.6 7.6e-42 141.7 0.2 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 GAP84472.1 - 3.5e-34 117.9 2.5 1.4e-32 112.8 0.0 2.8 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 GAP84472.1 - 8e-33 112.8 12.1 2.6e-31 107.9 1.7 3.8 3 1 0 3 3 3 2 Multicopper oxidase Ras PF00071.17 GAP84473.1 - 1.1e-52 177.6 0.0 1.3e-52 177.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAP84473.1 - 9.8e-17 61.5 0.0 1.4e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAP84473.1 - 4.8e-10 38.9 0.0 1.3e-09 37.4 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAP84473.1 - 2.8e-06 26.6 0.0 3.3e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAP84473.1 - 0.0013 18.6 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 GAP84473.1 - 0.0027 16.9 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 GAP84473.1 - 0.0069 15.1 0.0 0.0073 15.0 0.0 1.2 1 1 0 1 1 1 1 G-protein alpha subunit GTP_EFTU PF00009.22 GAP84473.1 - 0.076 12.4 0.0 0.41 10.0 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_21 PF13304.1 GAP84473.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain CWC25 PF12542.3 GAP84474.1 - 1.9e-22 79.4 0.0 1.9e-22 79.4 0.0 4.0 4 1 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 GAP84474.1 - 2.3e-13 49.9 2.3 2.3e-13 49.9 1.6 4.2 5 1 1 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR PCI PF01399.22 GAP84475.1 - 3.3e-18 65.9 1.4 5.4e-18 65.2 0.1 2.1 2 1 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 GAP84475.1 - 1.4e-07 31.3 0.2 4.2e-07 29.8 0.1 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Pkinase_Tyr PF07714.12 GAP84475.1 - 0.0071 15.4 0.4 0.098 11.7 0.1 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase TPR_7 PF13176.1 GAP84475.1 - 0.022 14.5 1.9 1.7 8.6 0.1 4.3 5 1 0 5 5 5 0 Tetratricopeptide repeat FeoC PF09012.5 GAP84475.1 - 0.029 14.0 0.0 0.087 12.5 0.0 1.8 1 0 0 1 1 1 0 FeoC like transcriptional regulator TPR_2 PF07719.12 GAP84475.1 - 0.071 13.0 3.9 1.3 9.0 0.1 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Ipi1_N PF12333.3 GAP84475.1 - 0.093 12.7 0.3 0.31 11.0 0.1 1.9 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation TPR_10 PF13374.1 GAP84475.1 - 0.16 11.9 0.4 18 5.4 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Sigma70_ner PF04546.8 GAP84475.1 - 0.22 11.0 4.1 0.53 9.8 2.8 1.7 1 1 0 1 1 1 0 Sigma-70, non-essential region TPR_12 PF13424.1 GAP84475.1 - 0.42 10.5 3.1 1.1 9.2 0.2 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 GAP84475.1 - 0.55 9.9 2.7 2 8.1 0.1 3.0 4 0 0 4 4 3 0 TPR repeat NUDIX PF00293.23 GAP84476.1 - 4.4e-17 61.9 0.0 7.1e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NmrA PF05368.8 GAP84477.1 - 8e-12 44.9 0.0 9.5e-12 44.6 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAP84477.1 - 0.0014 18.7 0.1 0.0014 18.6 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding WD40 PF00400.27 GAP84478.1 - 5.4e-09 35.5 0.6 8.8e-06 25.4 0.1 4.4 5 0 0 5 5 5 1 WD domain, G-beta repeat DUF3312 PF11768.3 GAP84478.1 - 0.016 13.5 0.0 0.58 8.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) SKG6 PF08693.5 GAP84480.1 - 0.073 12.3 1.3 0.13 11.6 0.9 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.1 GAP84480.1 - 4.2 7.8 0.0 4.2 7.8 0.0 3.1 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Activator_LAG-3 PF11498.3 GAP84480.1 - 8 5.0 36.3 14 4.2 25.2 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 PFK PF00365.15 GAP84481.1 - 1.4e-168 559.0 0.7 1.2e-121 405.0 1.2 2.1 2 0 0 2 2 2 2 Phosphofructokinase Med17 PF10156.4 GAP84482.1 - 1.4e-75 254.3 0.0 1.7e-75 254.1 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex IncA PF04156.9 GAP84483.1 - 2.1 7.8 5.5 6.1 6.3 0.2 2.2 2 0 0 2 2 2 0 IncA protein KAR9 PF08580.5 GAP84484.1 - 3.1 5.9 10.8 4.4 5.4 7.5 1.3 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF605 PF04652.11 GAP84484.1 - 9.5 5.5 12.3 19 4.5 8.5 1.5 1 0 0 1 1 1 0 Vta1 like CBFD_NFYB_HMF PF00808.18 GAP84485.1 - 1.1e-17 63.7 0.2 1.9e-17 63.0 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAP84485.1 - 0.00012 22.1 0.0 0.00027 21.0 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 adh_short PF00106.20 GAP84486.1 - 9.4e-31 106.9 0.7 1.5e-30 106.3 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP84486.1 - 6.7e-13 48.9 0.0 8.6e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP84486.1 - 1.6e-11 44.2 0.8 3.7e-11 43.0 0.3 1.6 1 1 1 2 2 2 2 KR domain NAD_binding_10 PF13460.1 GAP84486.1 - 0.0021 18.0 0.4 0.004 17.1 0.3 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAP84486.1 - 0.014 14.8 0.1 0.082 12.3 0.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAP84486.1 - 0.05 12.5 0.7 7 5.4 0.3 2.5 2 1 1 3 3 3 0 Male sterility protein DUF1776 PF08643.5 GAP84486.1 - 0.091 11.8 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Borrelia_REV PF03978.8 GAP84487.1 - 0.15 11.8 0.0 0.96 9.1 0.0 2.1 2 0 0 2 2 2 0 Borrelia burgdorferi REV protein MFS_1 PF07690.11 GAP84488.1 - 1.7e-41 142.1 33.0 1.7e-41 142.1 22.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP84488.1 - 3.3e-06 25.9 9.1 3.3e-06 25.9 6.3 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter DUF4231 PF14015.1 GAP84488.1 - 0.019 14.9 0.0 0.019 14.9 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) DUF3405 PF11885.3 GAP84489.1 - 4.2e-184 612.4 0.1 6.1e-184 611.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Abhydrolase_6 PF12697.2 GAP84491.1 - 1.2e-10 41.7 2.3 1.7e-10 41.2 1.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAP84491.1 - 2.1e-08 34.0 0.0 3.9e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 GAP84491.1 - 2.1e-06 27.5 1.4 2.9e-06 27.1 0.4 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 GAP84491.1 - 8.7e-06 25.1 0.0 2.9e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 GAP84491.1 - 5e-05 22.9 0.0 6.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 GAP84491.1 - 0.00048 19.2 0.0 0.00074 18.5 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Glyco_trans_4_4 PF13579.1 GAP84491.1 - 0.0017 18.5 1.5 0.033 14.3 0.2 2.4 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Lipase_2 PF01674.13 GAP84491.1 - 0.0046 16.2 0.0 0.042 13.1 0.0 2.2 2 0 0 2 2 2 1 Lipase (class 2) DUF900 PF05990.7 GAP84491.1 - 0.014 14.7 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF915 PF06028.6 GAP84491.1 - 0.028 13.4 0.0 0.061 12.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.15 GAP84491.1 - 0.03 14.5 0.0 0.044 14.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Ser_hydrolase PF06821.8 GAP84491.1 - 0.038 13.5 0.1 0.087 12.4 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase Peptidase_S10 PF00450.17 GAP84493.1 - 7.6e-113 377.8 0.1 1e-112 377.3 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 GAP84493.1 - 0.011 15.5 0.0 0.08 12.8 0.0 2.3 2 1 0 2 2 2 0 Alpha/beta hydrolase family Minor_tail_Z PF06763.6 GAP84493.1 - 0.069 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Prophage minor tail protein Z (GPZ) NOSIC PF08060.8 GAP84493.1 - 0.28 11.0 0.9 0.63 9.8 0.2 1.8 2 0 0 2 2 2 0 NOSIC (NUC001) domain zf-MIZ PF02891.15 GAP84494.1 - 3.2e-07 29.7 6.2 2.9e-06 26.6 4.3 2.3 1 1 0 1 1 1 1 MIZ/SP-RING zinc finger SAM_2 PF07647.12 GAP84495.1 - 4.9e-14 51.9 0.0 9.8e-14 50.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 GAP84495.1 - 1.1e-13 50.5 0.1 3.7e-13 48.8 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 GAP84495.1 - 7.1e-12 44.5 0.0 1.4e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 GAP84495.1 - 5.6e-09 36.1 0.0 1.3e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAP84495.1 - 1.4e-06 28.4 0.1 4.3e-06 26.9 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.12 GAP84495.1 - 1.3e-05 24.5 0.0 2.7e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 GAP84495.1 - 0.054 13.6 0.1 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PH_8 PF15409.1 GAP84495.1 - 0.062 13.3 0.0 0.39 10.8 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Gastrin PF00918.12 GAP84495.1 - 0.2 12.5 0.0 0.2 12.5 0.0 3.3 4 0 0 4 4 4 0 Gastrin/cholecystokinin family Formyl_trans_N PF00551.14 GAP84496.1 - 3.6e-19 68.9 0.0 5.3e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase HABP4_PAI-RBP1 PF04774.10 GAP84497.1 - 0.0084 16.6 5.4 0.02 15.4 3.7 1.6 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family Dehydrin PF00257.14 GAP84497.1 - 0.32 11.3 3.6 0.44 10.8 2.5 1.3 1 1 0 1 1 1 0 Dehydrin DUF1279 PF06916.8 GAP84498.1 - 5.7e-29 100.2 0.0 1.8e-28 98.6 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) GMC_oxred_N PF00732.14 GAP84499.1 - 4.7e-59 199.9 0.0 5.8e-59 199.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAP84499.1 - 5.9e-32 110.9 0.0 1e-31 110.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAP84499.1 - 6e-09 35.2 2.3 0.0016 17.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAP84499.1 - 3e-08 32.9 0.2 0.00014 20.8 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAP84499.1 - 1.7e-07 31.5 0.2 0.00022 21.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP84499.1 - 1.4e-05 25.0 0.6 4.7e-05 23.3 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAP84499.1 - 1.4e-05 25.4 2.8 0.02 15.2 0.2 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAP84499.1 - 7e-05 22.7 2.5 0.046 13.5 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAP84499.1 - 0.00085 18.3 0.3 0.0014 17.6 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 GAP84499.1 - 0.0067 14.9 1.2 0.031 12.7 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 GAP84499.1 - 0.012 14.7 1.9 0.012 14.7 0.2 1.7 2 0 0 2 2 2 0 Thi4 family K_oxygenase PF13434.1 GAP84499.1 - 0.027 13.4 0.2 4.2 6.1 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.13 GAP84499.1 - 0.03 14.3 0.3 0.23 11.4 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.1 GAP84499.1 - 0.048 13.4 2.0 0.11 12.2 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 GAP84499.1 - 0.1 11.2 0.4 0.19 10.2 0.3 1.4 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.2 GAP84499.1 - 0.62 9.0 7.8 0.48 9.4 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase MARVEL PF01284.18 GAP84500.1 - 2.8e-19 69.3 18.4 3.4e-19 69.0 12.8 1.0 1 0 0 1 1 1 1 Membrane-associating domain Tic20 PF09685.5 GAP84500.1 - 2.1 8.3 13.5 1.4 8.9 7.4 1.9 2 0 0 2 2 2 0 Tic20-like protein Glyco_hydro_43 PF04616.9 GAP84501.1 - 7.4e-71 238.5 1.2 9.4e-71 238.2 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Sugar_tr PF00083.19 GAP84502.1 - 1.1e-99 334.0 17.3 1.3e-99 333.8 12.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP84502.1 - 3.3e-24 85.2 32.3 3.4e-23 81.9 16.4 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAP84502.1 - 9.5e-07 27.3 1.0 1.4e-06 26.7 0.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 GAP84502.1 - 0.0038 16.9 0.1 0.0038 16.9 0.1 2.8 3 0 0 3 3 3 1 MFS_1 like family DUF1228 PF06779.9 GAP84502.1 - 0.017 15.1 8.1 0.73 9.8 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Fungal_trans PF04082.13 GAP84503.1 - 1.4e-15 56.8 1.6 2.6e-15 56.0 1.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 GAP84503.1 - 1.2e-07 31.6 11.3 0.0014 18.8 0.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP84503.1 - 2.5e-06 27.4 10.8 0.00027 21.0 1.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger DHO_dh PF01180.16 GAP84505.1 - 5.1e-17 61.7 0.0 7.7e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase zf-C3HC4_2 PF13923.1 GAP84505.1 - 4.6e-07 29.7 10.9 9.6e-07 28.7 7.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAP84505.1 - 1.4e-06 28.0 9.3 3.1e-06 26.8 6.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 GAP84505.1 - 5.6e-06 25.9 7.7 1e-05 25.1 5.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 GAP84505.1 - 1.3e-05 24.6 9.3 3e-05 23.5 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAP84505.1 - 2.2e-05 24.0 8.5 4.3e-05 23.0 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAP84505.1 - 0.00059 19.4 5.6 0.00087 18.9 2.8 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 GAP84505.1 - 0.0046 16.8 8.3 0.059 13.2 6.3 2.3 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING CFEM PF05730.6 GAP84506.1 - 0.15 11.8 11.4 0.36 10.6 7.9 1.9 1 1 0 1 1 1 0 CFEM domain Oxidored_q6 PF01058.17 GAP84507.1 - 6.3e-22 77.5 0.0 1e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit F-box-like PF12937.2 GAP84509.1 - 0.012 15.3 0.1 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 F-box-like CTP_transf_2 PF01467.21 GAP84510.1 - 1.6e-21 77.0 0.0 2.7e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase Tctex-1 PF03645.8 GAP84511.1 - 5.9e-33 112.7 0.0 6.9e-33 112.5 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family DUF202 PF02656.10 GAP84512.1 - 0.0063 16.6 2.1 0.02 15.0 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Cyt_c_ox_IV PF12270.3 GAP84512.1 - 0.041 13.6 0.3 0.045 13.5 0.2 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Choline_transpo PF04515.7 GAP84512.1 - 0.12 11.0 1.1 0.15 10.8 0.8 1.1 1 0 0 1 1 1 0 Plasma-membrane choline transporter Phageshock_PspG PF09583.5 GAP84512.1 - 0.14 12.2 0.4 0.14 12.2 0.3 2.0 2 0 0 2 2 2 0 Phage shock protein G (Phageshock_PspG) DUF1029 PF06269.7 GAP84512.1 - 2.5 8.1 5.1 0.33 10.9 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1029) Hamartin PF04388.7 GAP84514.1 - 7.3 5.1 6.3 11 4.6 4.4 1.2 1 0 0 1 1 1 0 Hamartin protein HECT PF00632.20 GAP84515.1 - 4.9e-92 308.4 0.0 6.9e-92 307.9 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 GAP84515.1 - 1.5e-32 111.0 21.5 1.7e-11 43.7 4.6 3.9 3 0 0 3 3 3 3 WW domain C2 PF00168.25 GAP84515.1 - 2.8e-16 59.1 0.1 7.5e-16 57.7 0.0 1.8 1 0 0 1 1 1 1 C2 domain Apc3 PF12895.2 GAP84516.1 - 0.17 12.0 1.7 0.26 11.4 0.4 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 2-Hacid_dh_C PF02826.14 GAP84517.1 - 5.2e-44 149.5 0.0 8.5e-44 148.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAP84517.1 - 0.00042 19.7 0.0 0.00088 18.7 0.0 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_7 PF13241.1 GAP84517.1 - 0.0033 17.6 0.0 0.088 13.0 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding AdoHcyase_NAD PF00670.16 GAP84517.1 - 0.0097 15.7 0.0 0.2 11.4 0.0 2.2 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.1 GAP84517.1 - 0.016 15.5 0.0 0.055 13.7 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain Shikimate_DH PF01488.15 GAP84517.1 - 0.028 14.5 0.0 0.06 13.4 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.16 GAP84517.1 - 0.041 13.4 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase SNF2_N PF00176.18 GAP84518.1 - 1.7e-25 89.4 0.2 3.1e-25 88.5 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.10 GAP84518.1 - 1.2e-07 31.7 0.0 1.5e-06 28.1 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 GAP84518.1 - 0.0019 18.0 0.0 0.0046 16.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_11 PF13086.1 GAP84518.1 - 0.021 14.4 0.4 14 5.2 0.0 3.4 2 1 0 3 3 3 0 AAA domain DEAD PF00270.24 GAP84518.1 - 0.073 12.5 0.0 0.44 10.0 0.0 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase MFS_1 PF07690.11 GAP84519.1 - 1e-35 123.1 28.7 1e-35 123.1 19.9 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Cu-oxidase_3 PF07732.10 GAP84520.1 - 1.9e-40 137.2 4.0 2.5e-40 136.9 0.8 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 GAP84520.1 - 1.1e-37 128.5 8.2 1.6e-35 121.6 0.2 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 GAP84520.1 - 5.4e-36 123.8 1.2 5.4e-35 120.6 0.1 2.7 3 0 0 3 3 3 1 Multicopper oxidase HAD_2 PF13419.1 GAP84522.1 - 8.7e-15 55.3 0.1 9.3e-14 52.0 0.1 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAP84522.1 - 0.0057 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Ribosomal_L18p PF00861.17 GAP84523.1 - 9.7e-43 145.1 0.1 9.7e-43 145.1 0.1 2.2 3 0 0 3 3 3 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 GAP84523.1 - 2.2e-33 114.6 8.3 2.2e-33 114.6 5.8 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF4407 PF14362.1 GAP84523.1 - 1.9 7.3 5.7 3.3 6.5 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LRR_4 PF12799.2 GAP84525.1 - 8.4 6.1 16.6 1.5 8.5 1.3 5.4 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) ODV-E18 PF10717.4 GAP84526.1 - 1.3 8.5 6.0 2.2 7.7 0.0 3.5 4 0 0 4 4 4 0 Occlusion-derived virus envelope protein ODV-E18 His_Phos_1 PF00300.17 GAP84528.1 - 4.6e-18 65.7 0.0 6.1e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MRP_L53 PF10780.4 GAP84528.1 - 0.037 13.9 0.2 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 39S ribosomal protein L53/MRP-L53 MutS_II PF05188.12 GAP84528.1 - 0.1 12.6 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 MutS domain II PBP_sp32 PF07222.7 GAP84529.1 - 0.039 13.1 4.3 0.068 12.3 3.0 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 adh_short PF00106.20 GAP84530.1 - 2.3e-10 40.6 12.0 1.7e-07 31.3 1.5 4.0 4 0 0 4 4 4 3 short chain dehydrogenase KR PF08659.5 GAP84530.1 - 0.00013 21.7 0.7 0.00041 20.0 0.5 1.9 1 0 0 1 1 1 1 KR domain Voldacs PF03517.8 GAP84530.1 - 0.005 16.6 0.5 0.19 11.6 0.0 2.2 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling Eno-Rase_NADH_b PF12242.3 GAP84530.1 - 0.028 14.2 0.3 0.062 13.0 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 GAP84530.1 - 0.035 14.1 1.2 0.055 13.4 0.1 1.9 2 0 0 2 2 2 0 NADH(P)-binding ApbA PF02558.11 GAP84530.1 - 0.038 13.4 0.2 0.1 12.0 0.2 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sporozoite_P67 PF05642.6 GAP84530.1 - 0.18 9.6 1.0 2.8 5.7 0.1 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen CDV3 PF15359.1 GAP84530.1 - 0.57 10.2 0.0 0.57 10.2 0.0 1.9 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 DUF3439 PF11921.3 GAP84530.1 - 0.97 9.2 5.8 2.3 8.0 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Nucleoplasmin PF03066.10 GAP84530.1 - 3.8 7.0 5.5 2 7.8 1.0 2.0 2 0 0 2 2 2 0 Nucleoplasmin Peptidase_S10 PF00450.17 GAP84531.1 - 7.3e-97 325.1 0.3 8.5e-97 324.9 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF4603 PF15376.1 GAP84532.1 - 1.9 5.5 7.9 2.5 5.1 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Ion_trans PF00520.26 GAP84533.1 - 0.0091 15.2 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 Ion transport protein Ribosomal_60s PF00428.14 GAP84533.1 - 1.3 9.4 7.0 3.4 8.1 4.8 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Herpes_LP PF03363.8 GAP84534.1 - 0.063 12.8 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus leader protein SUR7 PF06687.7 GAP84535.1 - 1.9e-18 66.8 14.3 1.9e-18 66.8 9.9 1.9 1 1 1 2 2 2 1 SUR7/PalI family DuoxA PF10204.4 GAP84535.1 - 0.14 11.2 4.7 0.048 12.7 1.4 1.6 2 0 0 2 2 2 0 Dual oxidase maturation factor SPT16 PF08644.6 GAP84536.1 - 1.1e-57 194.1 0.1 1.1e-57 194.1 0.1 3.0 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 GAP84536.1 - 4.6e-55 185.5 0.6 4.6e-55 185.5 0.4 2.2 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 GAP84536.1 - 7.8e-24 84.4 0.0 1.3e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 GAP84536.1 - 1e-22 79.8 0.1 3.4e-22 78.2 0.0 2.0 1 0 0 1 1 1 1 Histone chaperone Rttp106-like MFS_1 PF07690.11 GAP84537.1 - 4.3e-26 91.4 45.6 5.1e-22 78.0 19.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 GAP84538.1 - 2.3e-08 33.5 0.1 3.2e-08 33.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP84538.1 - 0.00041 19.5 0.0 0.00061 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 GAP84538.1 - 0.00044 19.3 0.0 0.00068 18.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAP84538.1 - 0.0019 17.9 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 GAP84538.1 - 0.095 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL WD40 PF00400.27 GAP84539.1 - 7.3e-61 200.0 18.8 9.9e-12 44.2 0.1 11.5 11 0 0 11 11 11 7 WD domain, G-beta repeat NACHT PF05729.7 GAP84539.1 - 3e-13 49.7 0.1 5.5e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 NACHT domain eIF2A PF08662.6 GAP84539.1 - 2.3e-08 33.9 0.0 0.063 12.9 0.0 4.4 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 GAP84539.1 - 3.3e-05 23.1 1.3 4.3 6.3 0.0 5.7 3 1 3 6 6 6 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 GAP84539.1 - 4.9e-05 22.8 0.4 8 6.2 0.0 6.3 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 GAP84539.1 - 0.00013 20.8 0.6 0.17 10.5 0.0 4.0 2 2 0 2 2 2 1 Nup133 N terminal like PQQ_2 PF13360.1 GAP84539.1 - 0.0014 18.1 5.2 0.77 9.1 3.5 3.4 1 1 0 1 1 1 1 PQQ-like domain AAA_16 PF13191.1 GAP84539.1 - 0.0076 16.2 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain UPF0079 PF02367.12 GAP84539.1 - 0.018 14.6 0.0 0.052 13.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Nup160 PF11715.3 GAP84539.1 - 0.019 13.0 6.2 0.11 10.6 0.3 4.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PIF1 PF05970.9 GAP84539.1 - 0.066 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Inhibitor_I69 PF13734.1 GAP84539.1 - 0.069 13.2 0.0 3.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Spi protease inhibitor DUF1513 PF07433.6 GAP84539.1 - 0.08 11.8 0.1 5.2 5.8 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1513) AAA_22 PF13401.1 GAP84539.1 - 0.086 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 GAP84539.1 - 0.12 11.2 0.2 1.8 7.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) p450 PF00067.17 GAP84540.1 - 1.5e-29 102.8 0.0 2.5e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 DUF2802 PF10975.3 GAP84540.1 - 0.096 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) ketoacyl-synt PF00109.21 GAP84541.1 - 2.9e-75 253.0 0.8 2.9e-75 253.0 0.5 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 GAP84541.1 - 1.7e-37 127.9 0.7 4e-37 126.6 0.5 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 GAP84541.1 - 6.6e-31 107.8 0.2 1e-26 94.0 0.0 2.3 2 0 0 2 2 2 2 Acyl transferase domain PS-DH PF14765.1 GAP84541.1 - 6.9e-18 64.8 0.0 1.8e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.7 GAP84541.1 - 4.8e-14 52.6 0.0 1.2e-13 51.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 GAP84541.1 - 2.4e-12 46.9 0.4 7.2e-12 45.3 0.3 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 GAP84541.1 - 2.6e-10 40.2 0.0 8.7e-10 38.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP84541.1 - 2.2e-07 31.2 0.0 7.8e-07 29.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP84541.1 - 7.3e-07 28.8 0.0 2e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP84541.1 - 1e-06 29.0 0.0 5.6e-06 26.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP84541.1 - 2.5e-06 28.0 0.0 1.1e-05 26.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 GAP84541.1 - 1.6e-05 24.0 0.4 3.5e-05 22.9 0.3 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_26 PF13659.1 GAP84541.1 - 0.00011 22.2 0.2 0.00035 20.5 0.2 1.9 1 0 0 1 1 1 1 Methyltransferase domain p450 PF00067.17 GAP84542.1 - 7.4e-51 173.1 0.0 1.1e-50 172.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.14 GAP84543.1 - 5.5e-52 176.7 2.9 5.1e-51 173.5 2.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAP84543.1 - 3.7e-35 121.3 0.0 6.3e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAP84543.1 - 4.3e-06 25.8 0.4 0.012 14.4 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 GAP84543.1 - 6.4e-05 22.9 0.3 0.017 15.0 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAP84543.1 - 0.00012 21.1 0.3 0.0064 15.4 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAP84543.1 - 0.0014 18.5 0.5 0.0042 17.0 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 GAP84543.1 - 0.061 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 GAP84543.1 - 0.065 12.1 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Maf1 PF09174.5 GAP84544.1 - 7.4e-59 198.6 0.0 1.1e-58 198.0 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator Clat_adaptor_s PF01217.15 GAP84545.1 - 2.1e-51 173.3 1.0 2.5e-51 173.1 0.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Aldo_ket_red PF00248.16 GAP84546.1 - 1.2e-11 43.9 0.0 1.6e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Kdo PF06293.9 GAP84547.1 - 5.6e-09 35.3 0.0 2.2e-05 23.6 0.0 2.3 2 1 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 GAP84547.1 - 1.6e-07 30.7 0.0 2.4e-07 30.1 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 GAP84547.1 - 1.9e-06 27.7 6.0 0.004 16.9 1.4 3.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 GAP84547.1 - 3.4e-05 23.2 0.1 0.0071 15.7 0.0 2.5 2 1 0 2 2 2 1 RIO1 family Pkinase_Tyr PF07714.12 GAP84547.1 - 3.6e-05 22.9 0.0 8.3e-05 21.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase PPDK_N PF01326.14 GAP84547.1 - 0.039 12.9 0.0 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain RRP7 PF12923.2 GAP84549.1 - 6.6e-36 123.2 12.4 6.6e-36 123.2 8.6 2.2 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) Ehbp PF10622.4 GAP84549.1 - 0.14 12.0 0.0 0.41 10.6 0.0 1.7 2 0 0 2 2 2 0 Energy-converting hydrogenase B subunit P (EhbP) MFS_1 PF07690.11 GAP84550.1 - 1.4e-49 168.7 35.8 7e-43 146.6 14.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.7 GAP84551.1 - 5e-07 29.4 0.0 9.3e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAP84551.1 - 3.9e-06 26.4 0.1 6.4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.13 GAP84552.1 - 2.2e-11 43.1 0.0 3.6e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S32 PF05579.8 GAP84552.1 - 0.11 11.5 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 DUF202 PF02656.10 GAP84553.1 - 5.9 7.1 15.8 19 5.5 3.4 4.2 3 1 0 3 3 3 0 Domain of unknown function (DUF202) Sugar_tr PF00083.19 GAP84554.1 - 1.2e-71 241.6 21.5 1.5e-71 241.3 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP84554.1 - 2.1e-23 82.6 23.9 3.1e-23 82.0 16.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 GAP84554.1 - 1e-05 24.1 2.7 1e-05 24.1 1.9 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein eIF-5_eIF-2B PF01873.12 GAP84556.1 - 6.3e-45 151.8 0.2 9.2e-45 151.3 0.2 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 ZapA PF05164.8 GAP84556.1 - 0.02 14.8 1.0 0.04 13.8 0.7 1.6 1 1 0 1 1 1 0 Cell division protein ZapA BRF1 PF07741.8 GAP84556.1 - 0.034 14.3 2.4 0.08 13.1 1.7 1.7 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Lar_restr_allev PF14354.1 GAP84556.1 - 0.042 14.1 0.2 0.11 12.8 0.2 1.7 1 0 0 1 1 1 0 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.7 GAP84556.1 - 0.14 11.5 0.5 0.27 10.5 0.4 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Arc_trans_TRASH PF08394.5 GAP84556.1 - 0.89 9.7 6.0 1.4 9.1 0.1 2.8 1 1 1 2 2 2 0 Archaeal TRASH domain HET PF06985.6 GAP84557.1 - 4.9e-21 75.3 7.2 1.2e-19 70.8 0.8 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF3425 PF11905.3 GAP84559.1 - 9.8e-21 74.0 1.1 2.7e-20 72.6 0.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 GAP84559.1 - 0.0011 18.8 11.7 0.013 15.4 8.1 2.1 1 1 0 1 1 1 1 bZIP transcription factor DUF904 PF06005.7 GAP84559.1 - 0.0064 16.7 1.9 0.011 15.9 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF904) Mnd1 PF03962.10 GAP84559.1 - 0.032 13.8 6.2 0.051 13.2 4.3 1.2 1 0 0 1 1 1 0 Mnd1 family ATG16 PF08614.6 GAP84559.1 - 0.12 12.1 7.5 0.2 11.4 5.2 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Lzipper-MIP1 PF14389.1 GAP84559.1 - 2.2 8.4 6.6 2.1 8.4 1.5 2.3 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 bZIP_2 PF07716.10 GAP84559.1 - 3.7 7.4 13.6 2.7 7.8 5.2 2.2 1 1 1 2 2 2 0 Basic region leucine zipper DivIC PF04977.10 GAP84559.1 - 5.5 6.5 6.6 18 4.9 4.6 1.8 1 1 0 1 1 1 0 Septum formation initiator PseudoU_synth_2 PF00849.17 GAP84560.1 - 8e-29 100.5 0.0 1.2e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Ub-Mut7C PF14451.1 GAP84560.1 - 0.063 12.8 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Mut7-C ubiquitin S4 PF01479.20 GAP84560.1 - 0.084 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 S4 domain 4HBT_2 PF13279.1 GAP84561.1 - 4e-08 33.7 0.0 5.1e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 GAP84561.1 - 9.3e-07 28.8 0.0 1.2e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 GAP84561.1 - 2.2e-05 23.5 0.6 3.8e-05 22.7 0.4 1.4 1 0 0 1 1 1 1 Acyl-ACP thioesterase GFO_IDH_MocA PF01408.17 GAP84562.1 - 3.7e-15 56.5 0.1 2.4e-14 53.8 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 GAP84562.1 - 3.9e-05 23.3 0.0 6.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Transglut_core PF01841.14 GAP84562.1 - 0.081 13.1 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily NmrA PF05368.8 GAP84563.1 - 6.8e-26 90.9 0.0 9.1e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAP84563.1 - 3.1e-11 43.6 0.6 8.5e-11 42.1 0.4 1.7 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 GAP84563.1 - 0.00066 18.7 0.0 0.00094 18.2 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 GAP84563.1 - 0.0024 16.6 0.0 0.0051 15.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3394 PF11874.3 GAP84563.1 - 0.079 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) Epimerase PF01370.16 GAP84563.1 - 0.2 11.0 0.1 0.2 11.0 0.1 1.9 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Acetyltransf_1 PF00583.19 GAP84564.1 - 6.3e-05 22.9 0.2 0.00013 21.9 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAP84564.1 - 0.022 14.8 0.1 0.04 14.0 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3328 PF11807.3 GAP84566.1 - 1.5e-37 129.4 0.6 1.8e-37 129.1 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) GFA PF04828.9 GAP84567.1 - 1.1e-21 76.5 0.0 1.5e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Zn_ribbon_recom PF13408.1 GAP84567.1 - 0.97 9.7 0.0 0.97 9.7 0.0 2.7 3 1 0 3 3 3 0 Recombinase zinc beta ribbon domain MBF1 PF08523.5 GAP84569.1 - 2.1e-19 69.2 1.0 4.1e-19 68.3 0.7 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 GAP84569.1 - 2.3e-09 36.9 0.0 3.3e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 GAP84569.1 - 0.00016 21.8 0.0 0.00026 21.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 GAP84569.1 - 0.0031 17.5 0.0 0.0045 17.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.1 GAP84569.1 - 0.033 13.5 0.0 0.086 12.2 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Dicty_REP PF05086.7 GAP84570.1 - 0.0011 16.8 10.4 0.01 13.6 2.9 2.1 2 0 0 2 2 2 2 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 GAP84570.1 - 0.0012 18.6 21.5 0.1 12.3 8.7 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3439) Mucin PF01456.12 GAP84570.1 - 0.44 10.3 29.8 0.06 13.1 7.5 3.0 3 0 0 3 3 3 0 Mucin-like glycoprotein GST_N_3 PF13417.1 GAP84574.1 - 0.0012 18.9 0.0 0.0024 18.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain eIF-4B PF06273.6 GAP84574.1 - 0.11 11.2 0.3 0.15 10.7 0.2 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Aft1_HRA PF11786.3 GAP84575.1 - 6.9e-26 90.3 9.2 6.9e-26 90.3 6.4 3.2 3 0 0 3 3 3 1 Aft1 HRA domain Aft1_HRR PF11787.3 GAP84575.1 - 7e-22 78.2 4.9 7e-22 78.2 3.4 3.8 3 1 0 3 3 3 1 Aft1 HRR domain bZIP_1 PF00170.16 GAP84575.1 - 6.9e-13 48.3 6.3 1.1e-12 47.6 4.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.3 GAP84575.1 - 4.8e-10 39.8 5.9 4.8e-10 39.8 4.1 3.6 4 1 0 4 4 4 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.10 GAP84575.1 - 2.5e-06 27.1 6.4 4.4e-06 26.4 4.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 GAP84575.1 - 0.0062 16.8 3.3 0.0062 16.8 2.3 1.9 2 0 0 2 2 2 1 bZIP Maf transcription factor Macoilin PF09726.4 GAP84575.1 - 0.31 9.2 7.2 0.41 8.8 5.0 1.1 1 0 0 1 1 1 0 Transmembrane protein MIS13 PF08202.6 GAP84576.1 - 2.5e-61 207.3 0.6 2.5e-61 207.3 0.4 2.1 2 0 0 2 2 2 1 Mis12-Mtw1 protein family Sdh5 PF03937.11 GAP84577.1 - 2.5e-23 81.5 0.1 4.8e-23 80.6 0.1 1.4 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase PAP1 PF08601.5 GAP84577.1 - 0.12 12.0 4.8 0.16 11.6 3.3 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Lamp PF01299.12 GAP84577.1 - 5.7 5.9 12.0 8.2 5.4 8.3 1.1 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Med3 PF11593.3 GAP84577.1 - 5.8 6.0 10.5 7.9 5.5 7.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF566 PF04484.7 GAP84577.1 - 7.6 5.9 7.2 13 5.1 5.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) EMP24_GP25L PF01105.19 GAP84578.1 - 2e-41 141.7 0.0 2.5e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.7 GAP84578.1 - 0.065 11.4 0.2 0.083 11.0 0.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA RE_SacI PF09566.5 GAP84578.1 - 0.065 12.1 0.0 0.099 11.5 0.0 1.3 1 1 0 1 1 1 0 SacI restriction endonuclease zf-U1 PF06220.7 GAP84579.1 - 5.5e-22 77.0 3.4 8.3e-22 76.4 2.3 1.3 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 GAP84579.1 - 0.019 15.0 3.4 0.041 14.0 2.4 1.5 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF2959 PF11172.3 GAP84580.1 - 0.062 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) SpoU_methylase PF00588.14 GAP84583.1 - 6.6e-26 90.8 0.0 1e-25 90.2 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 GAP84583.1 - 3e-08 33.7 0.0 5e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Ring_hydroxyl_B PF00866.13 GAP84583.1 - 0.034 13.8 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Ring hydroxylating beta subunit HET PF06985.6 GAP84584.1 - 4e-24 85.3 0.0 7.4e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-PHD-like PF15446.1 GAP84585.1 - 1.3e-68 229.6 9.7 2.3e-68 228.9 6.7 1.4 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 GAP84585.1 - 4.2e-54 183.3 0.0 5.8e-54 182.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAP84585.1 - 6.8e-15 54.6 0.0 1.5e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 GAP84585.1 - 1.7e-09 36.9 1.5 3.3e-09 36.0 1.1 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.19 GAP84585.1 - 9e-06 25.2 1.5 0.002 17.7 0.0 3.3 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.10 GAP84585.1 - 0.00013 21.8 0.0 0.00054 19.8 0.0 2.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit PHD PF00628.24 GAP84585.1 - 0.0041 16.7 4.3 0.0041 16.7 3.0 4.3 4 1 1 5 5 5 2 PHD-finger PHD_2 PF13831.1 GAP84585.1 - 0.0042 16.3 2.4 0.0042 16.3 1.7 3.4 4 0 0 4 4 4 1 PHD-finger ADK_lid PF05191.9 GAP84585.1 - 0.14 11.8 4.8 0.24 11.0 0.0 2.9 2 0 0 2 2 2 0 Adenylate kinase, active site lid adh_short PF00106.20 GAP84587.1 - 4.7e-23 81.9 0.3 6.5e-23 81.4 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP84587.1 - 1.5e-12 47.8 0.0 2.1e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP84587.1 - 9.1e-09 35.2 0.1 1.5e-08 34.5 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAP84587.1 - 7.5e-08 32.5 0.1 1.6e-07 31.4 0.1 1.6 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 GAP84587.1 - 2.1e-05 23.5 0.0 4e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 GAP84587.1 - 3.4e-05 23.4 0.0 9.8e-05 21.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAP84587.1 - 0.0006 19.5 0.7 0.0014 18.3 0.5 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 GAP84587.1 - 0.041 13.1 0.0 0.15 11.2 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family NACHT PF05729.7 GAP84588.1 - 6e-10 39.0 0.7 1.4e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 GAP84588.1 - 3.6e-06 27.1 3.4 2.1e-05 24.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain TMEM154 PF15102.1 GAP84588.1 - 0.00051 19.7 0.0 0.0014 18.3 0.0 1.7 1 0 0 1 1 1 1 TMEM154 protein family AAA_10 PF12846.2 GAP84588.1 - 0.011 15.2 0.3 0.037 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain SKG6 PF08693.5 GAP84588.1 - 0.017 14.4 1.6 0.042 13.1 1.1 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain cobW PF02492.14 GAP84588.1 - 0.052 12.9 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 GAP84588.1 - 0.066 13.5 0.5 0.31 11.3 0.0 2.2 2 1 0 2 2 2 0 ABC transporter AAA_29 PF13555.1 GAP84588.1 - 0.087 12.3 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1664 PF07889.7 GAP84588.1 - 9.9 5.9 9.7 16 5.2 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Acetyltransf_3 PF13302.1 GAP84589.1 - 4e-12 46.4 0.0 5.5e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAP84589.1 - 7e-07 29.1 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 GAP84589.1 - 0.00025 21.0 0.0 0.00037 20.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAP84589.1 - 0.005 16.7 0.0 0.0064 16.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Cutinase PF01083.17 GAP84590.1 - 1.3e-30 106.4 1.3 1.5e-30 106.2 0.9 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 GAP84590.1 - 0.00042 19.7 0.0 0.00056 19.3 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_5 PF12695.2 GAP84590.1 - 0.00083 19.1 0.2 0.001 18.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 GAP84590.1 - 0.0073 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 GAP84590.1 - 0.02 14.7 0.0 0.029 14.2 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF3089 PF11288.3 GAP84590.1 - 0.062 12.4 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) PMM PF03332.8 GAP84590.1 - 0.065 12.7 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic phosphomannomutase UPF0565 PF10561.4 GAP84590.1 - 0.12 11.2 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Mur_ligase_M PF08245.7 GAP84592.1 - 5.1e-05 23.3 0.0 0.00017 21.7 0.0 1.7 1 1 0 1 1 1 1 Mur ligase middle domain Methyltransf_23 PF13489.1 GAP84593.1 - 4.8e-09 36.1 0.0 8e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP84593.1 - 1.8e-06 28.3 0.0 3.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP84593.1 - 3.9e-05 24.1 0.0 0.00023 21.7 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP84593.1 - 0.00019 21.8 0.0 0.00049 20.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP84593.1 - 0.00024 20.7 0.0 0.0005 19.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP84593.1 - 0.00049 20.4 0.0 0.0012 19.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP84593.1 - 0.0009 19.2 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 GAP84593.1 - 0.003 16.8 0.0 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain MTS PF05175.9 GAP84593.1 - 0.0047 16.3 0.0 0.0078 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 GAP84593.1 - 0.07 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase DUF218 PF02698.12 GAP84594.1 - 1.7e-06 27.5 0.0 2.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain Abhydrolase_6 PF12697.2 GAP84595.1 - 6.2e-07 29.5 1.6 8.8e-07 29.0 1.0 1.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP84595.1 - 1.2e-06 28.3 0.2 1.8e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Zn_clus PF00172.13 GAP84596.1 - 7e-05 22.6 9.9 7e-05 22.6 6.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAP84596.1 - 0.00022 19.9 0.7 0.00097 17.8 0.5 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain CorA PF01544.13 GAP84597.1 - 6e-05 22.2 0.4 0.00013 21.0 0.0 1.8 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF4094 PF13334.1 GAP84597.1 - 0.0068 16.7 0.8 5.4 7.4 0.0 3.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4094) Pkinase PF00069.20 GAP84598.1 - 4e-36 124.5 0.0 1.3e-23 83.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAP84598.1 - 7.6e-18 64.5 0.0 6.4e-17 61.4 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase 4HBT_2 PF13279.1 GAP84599.1 - 7.2e-06 26.4 0.0 1e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily CFEM PF05730.6 GAP84600.1 - 4.1e-10 39.3 13.2 7.3e-10 38.5 9.1 1.4 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.15 GAP84600.1 - 0.21 11.6 3.2 0.39 10.7 2.2 1.4 1 0 0 1 1 1 0 Gamma-thionin family DUF3435 PF11917.3 GAP84601.1 - 1.2e-11 44.0 0.4 8.9e-06 24.6 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) CN_hydrolase PF00795.17 GAP84602.1 - 2.6e-26 92.1 0.0 5.8e-26 90.9 0.0 1.6 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 GAP84602.1 - 1.7e-23 82.7 0.0 6.1e-23 80.9 0.0 1.7 1 1 0 1 1 1 1 NAD synthase CorA PF01544.13 GAP84602.1 - 0.16 11.0 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein RF-1 PF00472.15 GAP84603.1 - 5.4e-34 116.4 1.3 1.2e-33 115.3 0.9 1.5 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 GAP84603.1 - 4.2e-24 84.4 0.0 2.1e-23 82.2 0.0 2.1 2 0 0 2 2 2 1 PCRF domain CorA PF01544.13 GAP84603.1 - 0.18 10.7 0.7 0.3 10.0 0.5 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Peptidase_S10 PF00450.17 GAP84604.1 - 4.3e-88 296.2 0.0 5.8e-88 295.8 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Pkinase PF00069.20 GAP84605.1 - 2e-70 236.9 0.0 3.6e-70 236.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP84605.1 - 8.8e-49 165.8 0.0 1.7e-48 164.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP84605.1 - 0.00039 19.4 0.0 0.0015 17.5 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 GAP84605.1 - 0.086 11.8 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MtrA PF04208.9 GAP84605.1 - 0.24 10.8 0.0 0.56 9.6 0.0 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A adh_short_C2 PF13561.1 GAP84606.1 - 1.1e-20 74.3 0.1 8.5e-20 71.5 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAP84606.1 - 3.5e-16 59.5 5.4 8.2e-16 58.3 3.8 1.6 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 GAP84606.1 - 2.8e-05 24.2 1.5 0.00011 22.2 0.8 1.9 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 GAP84606.1 - 0.0002 21.0 3.3 0.0002 21.0 0.8 2.0 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 GAP84606.1 - 0.00027 20.4 0.6 0.018 14.4 0.1 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 GAP84606.1 - 0.00085 19.3 0.2 0.0013 18.6 0.2 1.3 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 GAP84606.1 - 0.0065 15.4 0.4 0.011 14.7 0.3 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Pyr_redox PF00070.22 GAP84606.1 - 0.0087 16.4 0.6 0.017 15.4 0.4 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 GAP84606.1 - 0.015 14.7 0.3 0.023 14.1 0.2 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA B12-binding PF02310.14 GAP84606.1 - 0.015 15.1 0.2 0.025 14.4 0.2 1.4 1 0 0 1 1 1 0 B12 binding domain Methyltransf_18 PF12847.2 GAP84606.1 - 0.031 14.8 0.0 0.051 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.13 GAP84606.1 - 0.074 12.6 1.7 0.11 12.0 1.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 GAP84606.1 - 0.091 11.4 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_zinc_N PF00107.21 GAP84606.1 - 0.1 12.1 1.3 0.21 11.1 0.9 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 GAP84606.1 - 0.1 12.6 0.4 0.17 11.9 0.3 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Rad52_Rad22 PF04098.10 GAP84608.1 - 1.2e-61 206.9 0.0 1.7e-61 206.4 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Cut8_C PF08559.5 GAP84609.1 - 1.4e-46 157.8 0.0 2e-46 157.3 0.0 1.3 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 GAP84609.1 - 5.5e-14 51.6 0.4 1.1e-13 50.7 0.2 1.5 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 GAP84609.1 - 7.6e-08 32.2 0.4 1.7e-07 31.1 0.3 1.6 1 0 0 1 1 1 1 Cut8 proteasome-binding domain Lyase_aromatic PF00221.14 GAP84611.1 - 8.4e-160 532.2 2.3 1e-159 531.9 1.6 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase adh_short PF00106.20 GAP84612.1 - 1.7e-24 86.6 0.0 2.5e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP84612.1 - 4.1e-18 66.0 0.0 5.1e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP84612.1 - 1.2e-11 44.6 0.0 1.6e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAP84612.1 - 5e-06 26.1 0.1 1e-05 25.1 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAP84612.1 - 0.00019 21.5 0.1 0.0004 20.4 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 GAP84612.1 - 0.0048 15.8 0.0 0.0064 15.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.5 GAP84612.1 - 0.0095 15.0 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 GAP84612.1 - 0.042 13.6 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 GAP84612.1 - 0.053 12.7 0.0 0.49 9.6 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family F420_oxidored PF03807.12 GAP84612.1 - 0.085 13.3 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 GAP84613.1 - 7.4e-13 48.7 0.7 1.9e-12 47.4 0.5 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 GAP84613.1 - 3.1e-05 23.5 0.1 0.1 12.0 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.5 GAP84613.1 - 0.00049 19.7 0.2 0.0014 18.3 0.1 1.7 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 GAP84613.1 - 0.0082 15.9 0.1 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 GAP84613.1 - 0.062 12.1 0.3 0.19 10.6 0.1 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein FAD_binding_4 PF01565.18 GAP84614.1 - 1.8e-21 76.0 0.4 3.3e-21 75.2 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP84614.1 - 0.0002 21.2 0.2 0.00073 19.3 0.1 2.1 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_3 PF01494.14 GAP84615.1 - 2.5e-19 69.5 0.0 3.7e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAP84615.1 - 2e-10 40.1 0.3 2.3e-06 26.7 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAP84615.1 - 6.6e-07 29.2 0.8 1.5e-06 28.1 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAP84615.1 - 3.6e-06 27.2 0.1 0.0003 21.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 GAP84615.1 - 1.9e-05 23.9 1.4 0.0033 16.5 0.7 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 GAP84615.1 - 6.4e-05 21.9 0.8 0.00011 21.2 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 GAP84615.1 - 6.5e-05 21.5 0.1 0.0087 14.5 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 GAP84615.1 - 0.00018 21.4 0.0 0.0056 16.5 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP84615.1 - 0.00087 19.4 0.0 0.0025 17.9 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 GAP84615.1 - 0.007 15.8 0.2 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 GAP84615.1 - 0.012 14.4 0.3 0.018 13.9 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 GAP84615.1 - 0.017 14.9 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 GAP84615.1 - 0.023 13.6 0.0 0.38 9.6 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 GAP84615.1 - 0.027 13.5 0.1 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 GAP84615.1 - 0.034 13.8 0.1 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 GAP84615.1 - 0.12 12.3 0.2 0.48 10.4 0.1 1.9 2 0 0 2 2 2 0 NADH(P)-binding Cupin_2 PF07883.6 GAP84616.1 - 3.7e-08 32.7 0.0 7.1e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Cupin domain p450 PF00067.17 GAP84617.1 - 4.3e-61 206.8 0.0 5e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 COG2 PF06148.6 GAP84617.1 - 0.18 11.6 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 UbiA PF01040.13 GAP84618.1 - 6.3e-28 97.6 17.7 8e-28 97.3 12.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family NPP1 PF05630.6 GAP84621.1 - 1.2e-62 211.3 0.0 1.4e-62 211.1 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) HET PF06985.6 GAP84622.1 - 7.5e-23 81.2 0.9 2.2e-22 79.6 0.6 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Tubulin PF00091.20 GAP84623.1 - 9.1e-74 247.9 0.0 1.3e-73 247.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 GAP84623.1 - 4.7e-46 155.9 0.4 9.2e-46 154.9 0.0 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 GAP84623.1 - 3.7e-08 33.4 0.0 8.8e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain DUF3927 PF13064.1 GAP84624.1 - 0.1 12.0 0.5 0.29 10.6 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3927) WD40 PF00400.27 GAP84625.1 - 4.7e-27 92.8 3.8 8.6e-06 25.4 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 GAP84625.1 - 0.12 11.8 0.0 0.33 10.4 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_M24 PF00557.19 GAP84626.1 - 4.7e-42 143.9 0.0 6e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 NACHT PF05729.7 GAP84627.1 - 2.6e-05 23.9 0.0 9.3e-05 22.1 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAP84627.1 - 0.00046 20.3 0.0 0.0022 18.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain TPR_11 PF13414.1 GAP84627.1 - 0.0063 16.1 1.6 1 9.0 0.0 2.9 2 0 0 2 2 2 2 TPR repeat AAA_16 PF13191.1 GAP84627.1 - 0.049 13.6 0.1 0.94 9.4 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 GAP84627.1 - 0.062 13.4 0.0 0.3 11.2 0.0 2.3 1 0 0 1 1 1 0 RNA helicase TPR_2 PF07719.12 GAP84627.1 - 0.064 13.2 3.6 28 4.9 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat C2 PF00168.25 GAP84628.1 - 2e-10 40.3 0.0 3.5e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain DUF3668 PF12416.3 GAP84628.1 - 0.19 10.8 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 Cep120 protein DUF3653 PF12375.3 GAP84628.1 - 0.61 10.3 3.6 9.2 6.5 0.0 3.4 3 0 0 3 3 3 0 Phage protein DUF1053 PF06327.9 GAP84629.1 - 0.22 11.8 5.0 0.16 12.3 0.3 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1053) UPF0546 PF10639.4 GAP84630.1 - 1.3e-36 124.8 0.2 1.8e-36 124.3 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 EamA PF00892.15 GAP84630.1 - 0.0003 20.8 0.9 0.0068 16.4 0.8 2.2 2 0 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 GAP84630.1 - 0.015 15.4 2.3 0.015 15.4 1.6 1.6 2 0 0 2 2 2 0 Multidrug resistance efflux transporter DUF485 PF04341.7 GAP84630.1 - 0.11 12.2 0.7 2.1 8.1 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function, DUF485 UPF0060 PF02694.10 GAP84630.1 - 1.5 8.9 6.6 0.2 11.6 1.9 1.7 2 1 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family CH PF00307.26 GAP84632.1 - 1.9e-59 198.3 0.0 1.4e-15 57.2 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 GAP84632.1 - 0.00022 21.2 0.7 0.0049 16.9 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain pair MBOAT PF03062.14 GAP84633.1 - 4.4e-34 118.0 13.0 4.4e-34 118.0 9.0 2.7 2 1 1 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 GAP84633.1 - 1.6e-05 24.8 2.3 5.1e-05 23.2 1.6 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family RRM_1 PF00076.17 GAP84634.1 - 8.9e-12 44.4 0.0 1.3e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP84634.1 - 6.4e-08 32.4 0.0 1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP84634.1 - 1.1e-07 31.5 0.0 1.5e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAP84634.1 - 7.2e-05 22.4 0.0 0.0001 21.9 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Mito_carr PF00153.22 GAP84635.1 - 4.8e-75 247.3 4.8 3.5e-25 87.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L18e PF00828.14 GAP84636.1 - 1.1e-25 90.5 0.0 2e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 DUF159 PF02586.9 GAP84637.1 - 2.5e-58 197.0 0.0 4.5e-58 196.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Amidase_6 PF12671.2 GAP84637.1 - 0.0015 18.6 0.8 0.0033 17.4 0.6 1.6 1 0 0 1 1 1 1 Putative amidase domain Shadoo PF14999.1 GAP84638.1 - 0.057 13.2 2.6 0.07 12.9 1.8 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective IncA PF04156.9 GAP84638.1 - 0.34 10.4 2.2 0.51 9.9 1.5 1.4 1 1 0 1 1 1 0 IncA protein Tub_2 PF04525.7 GAP84639.1 - 1.2e-07 31.3 0.4 2e-07 30.5 0.3 1.3 1 1 0 1 1 1 1 Tubby C 2 NYAP_C PF15452.1 GAP84639.1 - 0.033 13.2 0.0 0.037 13.0 0.0 1.1 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter MBOAT_2 PF13813.1 GAP84640.1 - 3.8e-16 58.9 2.7 3.8e-16 58.9 1.9 2.3 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Cellulase PF00150.13 GAP84641.1 - 1.5e-50 172.0 0.0 1.8e-50 171.7 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_61 PF03443.9 GAP84642.1 - 3.7e-40 138.0 0.1 4.4e-40 137.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 GMC_oxred_N PF00732.14 GAP84643.1 - 4.7e-26 91.6 0.0 1.2e-25 90.2 0.0 1.8 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAP84643.1 - 9.2e-23 81.1 0.0 1.6e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAP84643.1 - 1.7e-07 30.5 0.0 0.00054 18.9 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAP84643.1 - 2.2e-06 26.7 0.0 0.002 17.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAP84643.1 - 8.5e-05 22.5 0.0 0.0002 21.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAP84643.1 - 0.00016 21.5 0.0 0.0006 19.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP84643.1 - 0.0007 19.7 0.3 0.14 12.1 0.1 2.8 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAP84643.1 - 0.0027 16.8 0.0 0.0048 16.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 GAP84643.1 - 0.0047 15.4 0.0 0.0069 14.9 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein DOMON PF03351.12 GAP84643.1 - 0.0055 16.6 0.0 0.031 14.2 0.0 2.2 2 0 0 2 2 2 1 DOMON domain Lycopene_cycl PF05834.7 GAP84643.1 - 0.0095 14.8 0.1 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Zn_clus PF00172.13 GAP84644.1 - 3.1e-07 30.1 7.0 5.8e-07 29.3 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAP84644.1 - 0.00024 20.0 0.0 0.00043 19.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain NifW PF03206.9 GAP84646.1 - 0.034 14.2 0.1 0.079 13.0 0.1 1.6 1 0 0 1 1 1 0 Nitrogen fixation protein NifW 6PF2K PF01591.13 GAP84647.1 - 7.4e-66 221.4 0.0 9.8e-66 221.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 GAP84647.1 - 3.1e-16 59.8 0.0 5.2e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 GAP84647.1 - 1.9e-07 31.0 0.0 4.4e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAP84647.1 - 7.9e-06 26.6 0.0 2.1e-05 25.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 GAP84647.1 - 0.0011 18.2 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 GAP84647.1 - 0.0044 16.1 0.0 0.0089 15.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Torsin PF06309.6 GAP84647.1 - 0.031 14.1 0.0 0.097 12.5 0.0 1.7 2 0 0 2 2 2 0 Torsin AAA_22 PF13401.1 GAP84647.1 - 0.07 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 GAP84647.1 - 0.084 12.3 0.0 0.17 11.3 0.0 1.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_18 PF13238.1 GAP84647.1 - 0.096 12.9 0.0 0.39 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Abhydrolase_3 PF07859.8 GAP84648.1 - 2.3e-55 187.4 0.1 3e-55 187.0 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 GAP84648.1 - 1.1e-09 37.6 0.0 3.2e-09 36.0 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 GAP84648.1 - 6.4e-06 25.9 0.0 1.2e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAP84648.1 - 0.00027 20.2 0.0 0.16 11.1 0.0 2.9 3 0 0 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.13 GAP84648.1 - 0.0014 17.9 0.0 0.024 13.9 0.0 2.6 3 0 0 3 3 3 1 Dienelactone hydrolase family Esterase_phd PF10503.4 GAP84648.1 - 0.0028 16.9 4.4 0.0028 16.9 0.1 2.4 2 1 0 2 2 2 1 Esterase PHB depolymerase AXE1 PF05448.7 GAP84648.1 - 0.053 12.0 0.1 0.25 9.8 0.1 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) IDO PF01231.13 GAP84649.1 - 2.6e-43 148.0 0.0 3.5e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase INO80_Ies4 PF08193.6 GAP84650.1 - 1.3e-47 162.6 18.7 1.4e-47 162.5 13.0 1.0 1 0 0 1 1 1 1 INO80 complex subunit Ies4 DUF605 PF04652.11 GAP84650.1 - 0.53 9.6 12.9 0.57 9.5 8.9 1.0 1 0 0 1 1 1 0 Vta1 like DUF4349 PF14257.1 GAP84650.1 - 9.3 5.3 6.9 0.64 9.1 0.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4349) CLTH PF10607.4 GAP84651.1 - 1.4e-36 125.3 0.2 5.7e-36 123.3 0.1 1.9 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 GAP84651.1 - 2.5e-24 85.7 0.1 4.2e-24 85.0 0.1 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 GAP84651.1 - 9.6e-05 22.0 1.6 0.00017 21.2 0.0 2.3 3 0 0 3 3 3 1 LisH DUF3123 PF11321.3 GAP84652.1 - 5.7 7.2 7.9 9.5 6.5 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) GST_C_3 PF14497.1 GAP84653.1 - 5.8e-06 26.7 0.1 8.6e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.4 GAP84653.1 - 0.00026 21.1 0.1 0.00069 19.8 0.0 1.6 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C PF00043.20 GAP84653.1 - 0.0086 16.0 0.0 0.028 14.3 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAP84653.1 - 0.019 14.8 0.6 0.036 13.9 0.4 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain adh_short_C2 PF13561.1 GAP84654.1 - 2.2e-19 70.1 0.0 5.1e-17 62.4 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAP84654.1 - 8e-13 48.6 2.8 2e-09 37.6 2.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase TFIIB PF00382.14 GAP84654.1 - 0.31 10.8 1.7 0.83 9.5 0.0 2.2 2 0 0 2 2 2 0 Transcription factor TFIIB repeat DUF4238 PF14022.1 GAP84655.1 - 3.8e-34 118.1 1.9 5.2e-34 117.7 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) DUF3129 PF11327.3 GAP84656.1 - 6.5e-28 97.7 11.5 6.5e-28 97.7 8.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3129) TPMT PF05724.6 GAP84657.1 - 1.6e-33 115.9 0.0 2.6e-28 98.9 0.0 2.1 2 0 0 2 2 2 2 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 GAP84657.1 - 3.4e-10 40.4 0.0 5.7e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP84657.1 - 1e-08 35.2 0.3 1.8e-08 34.4 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP84657.1 - 1.4e-08 34.5 0.0 3.1e-08 33.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP84657.1 - 1.9e-08 34.6 0.0 3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP84657.1 - 1.5e-07 31.8 0.0 3.1e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP84657.1 - 6.2e-07 29.1 0.0 1.5e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP84657.1 - 1.5e-06 28.4 0.0 2.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 GAP84657.1 - 0.002 17.3 0.0 0.0034 16.5 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB N2227 PF07942.7 GAP84657.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein Aldedh PF00171.17 GAP84658.1 - 4.6e-13 48.3 8.3 2.6e-08 32.6 3.3 2.4 1 1 0 2 2 2 2 Aldehyde dehydrogenase family URO-D PF01208.12 GAP84658.1 - 0.0023 16.9 0.0 0.0037 16.2 0.0 1.2 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Peptidase_M14 PF00246.19 GAP84659.1 - 1e-17 64.6 0.1 2.6e-17 63.3 0.0 1.7 2 0 0 2 2 2 1 Zinc carboxypeptidase AstE_AspA PF04952.9 GAP84659.1 - 0.00097 18.1 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.3 GAP84659.1 - 0.0046 16.0 0.0 0.0067 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) MFS_1 PF07690.11 GAP84661.1 - 2e-39 135.3 46.5 7.2e-36 123.6 17.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily PALP PF00291.20 GAP84662.1 - 3.6e-67 226.7 0.3 3.6e-67 226.7 0.2 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Transglut_core PF01841.14 GAP84662.1 - 0.12 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily DegT_DnrJ_EryC1 PF01041.12 GAP84662.1 - 0.15 11.0 0.3 0.23 10.4 0.2 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family IlvN PF07991.7 GAP84663.1 - 4e-46 156.3 0.0 5.8e-46 155.8 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 GAP84663.1 - 8.2e-45 152.2 0.0 1.4e-44 151.5 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 GAP84663.1 - 0.045 14.1 0.0 0.15 12.4 0.0 2.0 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 GAP84663.1 - 0.059 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase UQ_con PF00179.21 GAP84664.1 - 2e-36 124.4 0.0 2.9e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme eIF3_subunit PF08597.5 GAP84664.1 - 0.011 15.3 1.2 0.011 15.3 0.8 1.4 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Prok-E2_B PF14461.1 GAP84664.1 - 0.012 15.3 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 GAP84664.1 - 0.029 14.2 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 GAP84664.1 - 0.061 13.0 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 UEV domain Mcp5_PH PF12814.2 GAP84665.1 - 3.2e-46 156.2 0.1 8.8e-46 154.8 0.0 1.8 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Ras PF00071.17 GAP84666.1 - 2.5e-51 173.2 0.0 4.1e-51 172.5 0.0 1.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 GAP84666.1 - 1.3e-17 64.4 0.1 1.8e-15 57.5 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAP84666.1 - 0.00033 19.9 0.0 0.0011 18.2 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAP84666.1 - 0.02 14.8 0.0 0.027 14.4 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.13 GAP84666.1 - 0.037 13.2 0.1 0.29 10.4 0.0 2.1 2 1 0 2 2 2 0 Ferrous iron transport protein B Abhydrolase_4 PF08386.5 GAP84666.1 - 0.045 13.6 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 TAP-like protein AAA_25 PF13481.1 GAP84666.1 - 0.089 12.1 0.1 0.18 11.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 GAP84666.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region HAD_2 PF13419.1 GAP84667.1 - 6.1e-21 75.4 0.1 1.3e-20 74.3 0.1 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAP84667.1 - 2.1e-05 25.0 0.0 4.5e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAP84667.1 - 0.00086 18.9 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Opy2 PF09463.5 GAP84668.1 - 1.6e-09 37.6 20.6 2.7e-09 36.9 14.3 1.4 1 0 0 1 1 1 1 Opy2 protein Syndecan PF01034.15 GAP84668.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain P12 PF12669.2 GAP84668.1 - 0.2 11.8 0.0 0.2 11.8 0.0 2.4 2 1 0 2 2 2 0 Virus attachment protein p12 family Chitin_synth_1 PF01644.12 GAP84669.1 - 2.5e-71 238.7 0.1 4e-71 238.0 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 GAP84669.1 - 5.3e-26 90.1 0.1 1.1e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 GAP84669.1 - 1.8e-25 89.3 0.0 5.1e-21 74.6 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase OTU PF02338.14 GAP84669.1 - 7.3e-17 62.0 0.0 2.4e-16 60.4 0.0 2.0 1 1 0 1 1 1 1 OTU-like cysteine protease Glyco_trans_2_3 PF13632.1 GAP84669.1 - 3.3e-10 40.0 0.2 3.3e-10 40.0 0.1 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAP84669.1 - 1.1e-06 28.5 0.0 2.9e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Peptidase_C65 PF10275.4 GAP84669.1 - 0.0011 18.4 0.0 0.045 13.1 0.0 2.3 2 0 0 2 2 2 1 Peptidase C65 Otubain OPT PF03169.10 GAP84670.1 - 9.9e-128 427.2 45.9 1.1e-127 427.0 31.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF616 PF04765.8 GAP84670.1 - 0.22 10.6 0.1 0.35 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF616) APH PF01636.18 GAP84671.1 - 4.7e-09 36.3 0.0 5.5e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAP84671.1 - 0.012 15.1 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.15 GAP84671.1 - 0.16 11.0 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase DUF3405 PF11885.3 GAP84672.1 - 5.5e-174 579.0 0.4 7.8e-174 578.5 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) LIM PF00412.17 GAP84673.1 - 4.8e-24 84.1 17.0 5.2e-13 48.8 4.0 2.9 3 0 0 3 3 3 2 LIM domain TF_Zn_Ribbon PF08271.7 GAP84673.1 - 0.46 9.8 5.7 0.9 8.9 0.4 2.9 2 0 0 2 2 2 0 TFIIB zinc-binding NAD_binding_5 PF07994.7 GAP84674.1 - 2.1e-113 378.6 0.1 2.6e-113 378.4 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 GAP84674.1 - 1.2e-45 153.9 0.7 2.8e-45 152.7 0.5 1.7 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Aldo_ket_red PF00248.16 GAP84676.1 - 1.1e-42 145.8 0.0 1.5e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Ribonuc_L-PSP PF01042.16 GAP84676.1 - 1.4e-12 47.4 0.0 4.4e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 Endoribonuclease L-PSP PIF1 PF05970.9 GAP84677.1 - 6.3e-38 130.6 0.0 1.6e-27 96.3 0.0 2.5 2 1 1 3 3 3 2 PIF1-like helicase AAA_30 PF13604.1 GAP84677.1 - 2e-18 66.6 0.0 2e-16 60.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.9 GAP84677.1 - 7.5e-07 27.3 0.0 2.2e-05 22.4 0.0 2.6 3 0 0 3 3 3 1 Helicase NTPase_1 PF03266.10 GAP84677.1 - 1.7e-06 27.8 0.0 0.017 14.8 0.0 2.8 3 0 0 3 3 3 2 NTPase Viral_helicase1 PF01443.13 GAP84677.1 - 5.8e-06 25.9 1.0 0.11 12.0 0.1 3.6 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 GAP84677.1 - 1.4e-05 25.2 0.0 3.9e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 GAP84677.1 - 8.4e-05 21.4 0.2 0.00014 20.7 0.1 1.2 1 0 0 1 1 1 1 ArgK protein UvrD_C_2 PF13538.1 GAP84677.1 - 0.00016 21.7 0.0 0.00049 20.1 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 GAP84677.1 - 0.0004 20.4 0.0 0.0015 18.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 GAP84677.1 - 0.0012 18.7 0.0 0.0044 16.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAP84677.1 - 0.0025 17.5 0.1 0.006 16.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 GAP84677.1 - 0.0037 16.9 0.1 0.023 14.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 GAP84677.1 - 0.004 16.1 0.0 0.0079 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA PF00004.24 GAP84677.1 - 0.0069 16.5 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 GAP84677.1 - 0.0098 16.1 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 GAP84677.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DEAD PF00270.24 GAP84677.1 - 0.015 14.8 0.0 0.7 9.3 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase PRK PF00485.13 GAP84677.1 - 0.059 12.9 0.1 0.28 10.7 0.0 2.0 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family TrwB_AAD_bind PF10412.4 GAP84677.1 - 0.061 11.9 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain APS_kinase PF01583.15 GAP84677.1 - 0.067 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.1 GAP84677.1 - 0.068 13.9 0.1 0.35 11.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain PhoH PF02562.11 GAP84677.1 - 0.12 11.6 0.0 0.42 9.8 0.0 1.8 3 0 0 3 3 2 0 PhoH-like protein KTI12 PF08433.5 GAP84677.1 - 0.17 11.1 0.0 0.37 9.9 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 DUF1996 PF09362.5 GAP84678.1 - 2.5e-86 289.1 0.2 3.3e-86 288.7 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) AMP-binding PF00501.23 GAP84679.1 - 1.1e-79 267.7 0.0 1.4e-79 267.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAP84679.1 - 3.6e-10 40.6 0.1 8.5e-10 39.4 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pyr_redox_2 PF07992.9 GAP84680.1 - 3.5e-15 56.4 0.0 5.1e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAP84680.1 - 0.00062 18.7 0.4 0.011 14.6 0.1 2.4 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.9 GAP84680.1 - 0.0012 17.4 0.1 0.0019 16.7 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 GAP84680.1 - 0.0019 18.3 0.6 0.14 12.2 0.1 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAP84680.1 - 0.0032 16.5 0.3 0.007 15.4 0.1 1.6 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 GAP84680.1 - 0.0039 17.1 0.0 0.0085 16.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAP84680.1 - 0.0056 15.6 1.7 0.0076 15.1 0.4 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 GAP84680.1 - 0.011 14.6 0.1 0.025 13.4 0.0 1.6 1 1 1 2 2 2 0 Glucose inhibited division protein A K_oxygenase PF13434.1 GAP84680.1 - 0.033 13.1 0.5 0.28 10.0 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 GAP84680.1 - 0.05 12.5 0.6 0.15 10.9 0.2 1.7 1 1 0 2 2 2 0 Lycopene cyclase protein Cyt-b5 PF00173.23 GAP84681.1 - 2.8e-15 55.8 0.0 4.3e-14 52.0 0.0 2.7 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain IDO PF01231.13 GAP84681.1 - 1.2e-11 43.6 0.0 8.7e-11 40.8 0.0 2.0 2 0 0 2 2 2 1 Indoleamine 2,3-dioxygenase NAD_binding_1 PF00175.16 GAP84681.1 - 4.2e-09 36.9 0.0 1.1e-08 35.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.15 GAP84681.1 - 7.6e-09 35.3 0.0 7.4e-07 28.8 0.0 2.7 2 0 0 2 2 2 1 FAD binding domain Lipase_GDSL PF00657.17 GAP84682.1 - 5.7e-10 39.4 3.3 9.2e-10 38.7 2.3 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 GAP84682.1 - 7.1e-09 36.0 5.6 1.6e-08 34.8 3.9 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DPBB_1 PF03330.13 GAP84683.1 - 1.3e-06 28.3 0.4 2.3e-06 27.4 0.3 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 GAP84683.1 - 0.013 15.2 0.1 0.015 14.9 0.0 1.3 1 0 0 1 1 1 0 Barwin family DUF221 PF02714.10 GAP84684.1 - 2.2e-90 302.8 14.7 3.3e-90 302.2 10.2 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 GAP84684.1 - 5.5e-36 123.5 2.2 5.5e-36 123.5 1.5 2.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 GAP84684.1 - 4.3e-17 62.3 0.2 9.8e-17 61.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) A_deaminase PF00962.17 GAP84686.1 - 2.8e-41 141.5 0.0 3.2e-40 138.0 0.0 2.0 1 1 0 1 1 1 1 Adenosine/AMP deaminase NmrA PF05368.8 GAP84687.1 - 1.9e-08 33.8 0.0 5.3e-08 32.3 0.0 1.7 2 1 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 GAP84687.1 - 1.5e-07 31.5 0.0 2.8e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 GAP84687.1 - 0.00072 18.6 0.0 0.001 18.1 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 GAP84687.1 - 0.058 13.4 0.0 0.12 12.5 0.0 1.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 GAP84687.1 - 0.12 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 GAP84687.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding CsbD PF05532.7 GAP84688.1 - 2e-18 65.8 20.4 2.9e-09 36.4 2.0 3.3 2 1 1 3 3 3 3 CsbD-like Aminotran_5 PF00266.14 GAP84689.1 - 4.1e-93 312.0 0.0 4.9e-93 311.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 GAP84689.1 - 2.6e-07 30.0 0.0 3.5e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 GAP84689.1 - 3.2e-05 23.1 0.0 6e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 GAP84689.1 - 0.00011 20.8 0.0 0.00015 20.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.15 GAP84689.1 - 0.017 13.4 0.0 0.025 12.8 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme BAR PF03114.13 GAP84690.1 - 3.2e-63 213.3 6.5 4e-63 213.0 4.5 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 GAP84690.1 - 1.7e-14 52.9 0.0 3.1e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAP84690.1 - 3.4e-13 48.9 0.0 5.7e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAP84690.1 - 1.3e-10 40.6 0.1 2.6e-10 39.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain AMP-binding PF00501.23 GAP84691.1 - 1.3e-161 537.7 0.0 5.1e-87 291.9 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 GAP84691.1 - 9.7e-114 379.2 0.0 2.9e-61 206.9 0.0 3.4 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.20 GAP84691.1 - 1.9e-31 108.0 0.1 1e-09 38.5 0.0 3.9 3 0 0 3 3 3 3 Phosphopantetheine attachment site ApbA_C PF08546.6 GAP84691.1 - 7.7e-31 106.6 0.0 2.1e-30 105.2 0.0 1.9 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 GAP84691.1 - 3.5e-25 88.1 0.0 7.9e-25 87.0 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HxxPF_rpt PF13745.1 GAP84691.1 - 1.2e-22 80.0 1.1 8.5e-22 77.2 0.4 2.5 2 0 0 2 2 2 1 HxxPF-repeated domain AMP-binding_C PF13193.1 GAP84691.1 - 6.3e-13 49.4 0.1 0.0026 18.6 0.0 4.2 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Methyltransf_26 PF13659.1 GAP84691.1 - 0.00034 20.6 0.0 0.0015 18.5 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP84691.1 - 0.0022 18.5 0.0 0.011 16.2 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP84691.1 - 0.0035 17.0 0.0 0.02 14.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP84691.1 - 0.0095 15.5 0.0 0.028 14.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP84691.1 - 0.021 15.2 0.0 0.064 13.7 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain GH3 PF03321.8 GAP84691.1 - 0.096 11.1 0.0 3.7 5.9 0.0 2.4 2 0 0 2 2 2 0 GH3 auxin-responsive promoter PMI_typeI PF01238.16 GAP84692.1 - 2.9e-120 401.6 0.0 3.4e-120 401.4 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 GAP84692.1 - 0.0084 15.7 0.0 5.9 6.5 0.0 2.6 2 0 0 2 2 2 2 AraC-like ligand binding domain F-box-like PF12937.2 GAP84695.1 - 5.6e-07 29.1 0.2 2.1e-06 27.3 0.2 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 GAP84695.1 - 0.0093 15.6 1.0 1.4 8.6 0.1 2.8 3 0 0 3 3 3 2 F-box domain Meth_synt_2 PF01717.13 GAP84696.1 - 7.5e-16 58.0 0.0 7.4e-12 44.8 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 GAP84696.1 - 0.0027 17.0 0.0 0.1 11.8 0.0 2.5 2 1 0 2 2 2 1 Cobalamin-independent synthase, N-terminal domain B12-binding PF02310.14 GAP84696.1 - 0.057 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain 5_nucleotid_C PF02872.13 GAP84697.1 - 4.8e-35 120.8 0.0 2.1e-34 118.7 0.0 1.9 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 GAP84697.1 - 4.4e-08 32.7 0.0 7.2e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAP84697.1 - 0.074 12.8 0.0 0.17 11.7 0.0 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain EamA PF00892.15 GAP84698.1 - 7.2e-09 35.7 34.6 3.5e-06 27.0 2.0 2.9 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 GAP84698.1 - 6.8e-07 29.4 0.3 6.8e-07 29.4 0.2 3.0 3 1 0 3 3 3 1 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 GAP84698.1 - 0.012 14.7 0.2 0.012 14.7 0.2 1.7 2 0 0 2 2 2 0 Nucleotide-sugar transporter DUF914 PF06027.7 GAP84698.1 - 0.056 12.2 6.7 0.1 11.4 4.5 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 GAP84698.1 - 0.35 10.5 20.3 0.33 10.6 5.9 2.8 3 0 0 3 3 3 0 Triose-phosphate Transporter family Aldo_ket_red PF00248.16 GAP84699.1 - 2.7e-48 164.2 0.0 3.1e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MMR_HSR1 PF01926.18 GAP84700.1 - 7.3e-06 25.9 0.0 2.3e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.11 GAP84700.1 - 1.1e-05 24.5 0.0 2.5e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 GAP84700.1 - 0.0016 18.9 0.0 0.008 16.6 0.0 2.2 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 GAP84700.1 - 0.0029 16.8 0.0 0.0069 15.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 DUF4225 PF13988.1 GAP84700.1 - 0.0091 15.4 0.1 0.024 14.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4225) DUF3040 PF11239.3 GAP84700.1 - 0.01 15.8 0.0 0.044 13.8 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) IIGP PF05049.8 GAP84700.1 - 0.013 14.3 0.4 0.039 12.7 0.0 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.18 GAP84700.1 - 0.013 15.2 9.5 0.51 10.1 0.2 3.8 3 1 0 4 4 4 0 Dynamin family Viral_helicase1 PF01443.13 GAP84700.1 - 0.045 13.2 0.1 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF87 PF01935.12 GAP84700.1 - 0.074 12.8 0.0 0.074 12.8 0.0 2.9 2 1 0 2 2 1 0 Domain of unknown function DUF87 KAP_NTPase PF07693.9 GAP84700.1 - 0.089 11.7 0.0 0.44 9.4 0.0 2.1 1 1 0 1 1 1 0 KAP family P-loop domain ABC_tran PF00005.22 GAP84700.1 - 0.099 12.9 2.3 0.27 11.5 0.0 2.6 2 1 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.12 GAP84700.1 - 0.44 10.0 2.6 1.3 8.5 0.1 2.6 2 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Mt_ATP-synt_D PF05873.7 GAP84700.1 - 1.9 8.0 6.7 0.31 10.6 0.2 2.2 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) ATP-synt_E PF05680.7 GAP84700.1 - 3.6 7.6 11.0 6.3 6.8 1.4 2.6 2 0 0 2 2 2 0 ATP synthase E chain MMR_HSR1 PF01926.18 GAP84701.1 - 3.3e-09 36.6 0.0 9.1e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 GAP84701.1 - 1.8e-05 23.9 2.0 0.00052 19.1 0.0 2.4 2 0 0 2 2 2 1 AIG1 family Septin PF00735.13 GAP84701.1 - 0.00017 20.6 0.5 0.00034 19.7 0.0 1.7 2 0 0 2 2 2 1 Septin DUF258 PF03193.11 GAP84701.1 - 0.005 16.0 0.0 0.021 14.0 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 IIGP PF05049.8 GAP84701.1 - 0.0069 15.2 0.8 0.01 14.7 0.0 1.6 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.18 GAP84701.1 - 0.034 13.9 11.3 0.2 11.4 0.0 3.7 2 2 2 4 4 4 0 Dynamin family DUF45 PF01863.12 GAP84701.1 - 0.037 13.8 6.3 0.076 12.7 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF45 Kinetocho_Slk19 PF12709.2 GAP84701.1 - 0.041 13.9 1.2 0.041 13.9 0.8 3.1 2 1 0 3 3 3 0 Central kinetochore-associated DUF1266 PF06889.6 GAP84701.1 - 0.042 13.6 0.3 0.042 13.6 0.2 2.8 2 1 0 2 2 1 0 Protein of unknown function (DUF1266) AAA_22 PF13401.1 GAP84701.1 - 0.044 13.9 1.7 0.11 12.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 GAP84701.1 - 0.065 13.5 0.8 0.55 10.5 0.0 2.5 2 1 0 2 2 2 0 ABC transporter OmpH PF03938.9 GAP84701.1 - 0.069 13.0 13.7 0.11 12.3 9.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Miro PF08477.8 GAP84701.1 - 0.12 12.8 2.4 0.16 12.4 0.1 2.4 2 2 0 2 2 2 0 Miro-like protein ArgK PF03308.11 GAP84701.1 - 0.14 10.9 1.5 0.29 9.8 0.0 2.0 2 0 0 2 2 2 0 ArgK protein Mnd1 PF03962.10 GAP84701.1 - 0.14 11.8 17.9 0.15 11.7 9.9 2.4 2 1 1 3 3 3 0 Mnd1 family ATP_bind_1 PF03029.12 GAP84701.1 - 0.18 11.2 0.1 0.18 11.2 0.1 2.7 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.13 GAP84701.1 - 0.25 10.8 1.4 0.31 10.5 0.1 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.1 GAP84701.1 - 0.29 11.9 2.1 1.4 9.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain Striatin PF08232.7 GAP84701.1 - 0.7 10.1 18.1 0.095 13.0 7.2 2.3 1 1 1 2 2 2 0 Striatin family DUF342 PF03961.8 GAP84701.1 - 0.79 8.0 9.9 1.2 7.4 6.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) SRP54 PF00448.17 GAP84701.1 - 0.89 8.9 3.7 0.71 9.2 0.3 2.4 2 1 1 3 3 2 0 SRP54-type protein, GTPase domain Fib_alpha PF08702.5 GAP84701.1 - 2 8.5 7.8 1.1 9.4 0.6 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family FtsK_SpoIIIE PF01580.13 GAP84701.1 - 3.8 6.9 9.7 17 4.7 0.0 2.5 2 1 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.12 GAP84701.1 - 5.3 6.7 12.6 0.63 9.8 0.2 2.8 2 1 1 3 3 3 0 Domain of unknown function DUF87 tRNA-synt_2b PF00587.20 GAP84702.1 - 3.2e-63 212.4 0.0 6.1e-63 211.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAP84702.1 - 1.2e-19 70.0 0.0 9.3e-19 67.1 0.0 2.4 2 0 0 2 2 2 1 Anticodon binding domain Ank PF00023.25 GAP84703.1 - 4.6e-14 51.4 1.2 7.1e-06 25.5 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 GAP84703.1 - 1.2e-11 44.7 0.2 8e-05 22.9 0.3 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAP84703.1 - 1.1e-09 38.1 0.4 0.00012 22.1 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAP84703.1 - 1.4e-08 34.9 1.0 0.0022 18.4 0.5 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP84703.1 - 3.7e-08 32.8 0.1 0.03 14.5 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 GAP84703.1 - 2.3e-05 23.9 0.2 0.00014 21.4 0.1 2.3 1 1 0 1 1 1 1 KilA-N domain AAA_13 PF13166.1 GAP84703.1 - 0.0046 15.4 3.0 0.0098 14.4 2.1 1.5 1 0 0 1 1 1 1 AAA domain SlyX PF04102.7 GAP84703.1 - 5.8 7.3 10.9 0.077 13.3 0.6 3.2 4 0 0 4 4 4 0 SlyX Ribosomal_L34e PF01199.13 GAP84704.1 - 0.19 11.9 0.8 2.4 8.4 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein L34e Endonuclease_NS PF01223.18 GAP84705.1 - 0.00018 21.2 0.2 0.00056 19.5 0.1 1.8 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease adh_short PF00106.20 GAP84706.1 - 7.8e-23 81.2 5.6 1.2e-22 80.6 3.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP84706.1 - 3.4e-09 36.6 4.4 2.1e-08 34.0 3.1 2.1 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAP84706.1 - 4.7e-08 33.0 0.0 6e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAP84706.1 - 0.0027 17.7 0.6 0.0074 16.3 0.4 1.9 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_2 PF03446.10 GAP84706.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Saccharop_dh PF03435.13 GAP84706.1 - 0.14 11.1 0.4 0.2 10.6 0.0 1.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase Asp PF00026.18 GAP84707.1 - 2.1e-74 250.6 1.7 2.5e-74 250.4 1.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAP84707.1 - 8.7e-08 32.2 0.0 1.3e-06 28.4 0.0 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 GAP84707.1 - 0.0002 21.7 1.5 0.032 14.7 0.3 2.6 2 1 0 2 2 2 2 Aspartyl protease Voltage_CLC PF00654.15 GAP84708.1 - 2e-92 310.0 25.7 2e-92 310.0 17.8 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 GAP84708.1 - 9.3e-15 54.1 0.5 6.9e-07 28.9 0.0 2.7 2 0 0 2 2 2 2 CBS domain DUF754 PF05449.6 GAP84708.1 - 0.54 10.3 4.9 0.18 11.8 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF754) CBFD_NFYB_HMF PF00808.18 GAP84709.1 - 6.4e-11 42.1 0.0 1.8e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2057 PF09829.4 GAP84709.1 - 0.36 10.4 2.7 0.56 9.8 1.9 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) LRR_9 PF14580.1 GAP84710.1 - 2.9e-48 163.7 0.1 6.6e-48 162.5 0.0 1.6 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.1 GAP84710.1 - 1.3e-11 44.0 19.5 4e-06 26.4 1.7 3.1 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 GAP84710.1 - 3.9e-08 32.7 7.5 2.1e-05 24.0 1.7 3.5 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 GAP84710.1 - 0.002 18.0 0.3 7.7 6.9 0.9 3.3 3 0 0 3 3 3 2 Leucine Rich repeat LRR_7 PF13504.1 GAP84710.1 - 0.0032 17.4 3.8 3.3 8.3 0.9 4.4 4 0 0 4 4 4 1 Leucine rich repeat LRR_1 PF00560.28 GAP84710.1 - 0.063 13.3 7.1 27 5.3 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat PspB PF06667.7 GAP84710.1 - 0.1 12.5 1.2 0.32 10.9 0.9 1.8 1 0 0 1 1 1 0 Phage shock protein B DUF4349 PF14257.1 GAP84710.1 - 0.5 9.5 3.1 0.86 8.7 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Gag_spuma PF03276.9 GAP84711.1 - 0.8 7.9 6.7 0.089 11.1 0.8 2.0 2 0 0 2 2 2 0 Spumavirus gag protein Aldo_ket_red PF00248.16 GAP84712.1 - 2.4e-61 207.0 0.0 2.8e-61 206.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.13 GAP84713.1 - 3.8e-09 36.3 7.9 3.8e-09 36.3 5.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAP84713.1 - 0.00013 20.9 0.1 0.0012 17.8 0.0 2.2 1 1 1 2 2 2 1 Fungal specific transcription factor domain Lactonase PF10282.4 GAP84714.1 - 1.2e-84 284.3 0.0 1.9e-84 283.7 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller FPN1 PF06963.7 GAP84714.1 - 0.0055 15.1 0.6 0.0079 14.6 0.4 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) InvH PF04741.7 GAP84714.1 - 0.022 14.6 0.4 0.039 13.8 0.3 1.3 1 0 0 1 1 1 0 InvH outer membrane lipoprotein Pex14_N PF04695.8 GAP84714.1 - 0.077 13.0 2.7 0.18 11.8 1.9 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TMEM237 PF15383.1 GAP84714.1 - 0.081 12.0 0.3 0.12 11.4 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 FliP PF00813.15 GAP84714.1 - 0.23 11.1 0.8 0.33 10.6 0.1 1.5 2 0 0 2 2 2 0 FliP family Activator_LAG-3 PF11498.3 GAP84714.1 - 1 8.0 13.0 1.4 7.5 9.0 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 WD40 PF00400.27 GAP84716.1 - 1.6e-38 129.2 7.4 6.6e-10 38.4 0.3 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 GAP84716.1 - 9.7e-09 33.8 8.7 0.045 11.8 0.0 4.8 3 2 1 4 4 4 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 GAP84716.1 - 0.01 15.5 0.1 1.1 9.0 0.0 3.3 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region DUF3929 PF13066.1 GAP84716.1 - 0.016 14.9 0.1 9.9 6.0 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3929) PQQ_2 PF13360.1 GAP84716.1 - 0.025 14.0 1.3 0.6 9.5 0.2 2.7 2 1 0 2 2 2 0 PQQ-like domain CENP-F_leu_zip PF10473.4 GAP84716.1 - 0.36 10.7 2.5 0.65 9.8 1.8 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CM_2 PF01817.16 GAP84717.1 - 1.1e-06 28.6 0.2 0.0053 16.8 0.0 3.2 2 1 0 2 2 2 2 Chorismate mutase type II BCIP PF13862.1 GAP84718.1 - 2.9e-67 225.9 0.3 3.5e-67 225.6 0.2 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Cyclin_N PF00134.18 GAP84719.1 - 0.00023 20.7 0.1 0.0031 17.0 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain WD40 PF00400.27 GAP84721.1 - 3.1e-19 68.0 6.1 3.2e-05 23.6 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ATP_bind_1 PF03029.12 GAP84722.1 - 3.7e-76 255.8 0.0 4.6e-76 255.4 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 GAP84722.1 - 0.0026 16.5 0.0 0.0046 15.7 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_29 PF13555.1 GAP84722.1 - 0.048 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 GAP84722.1 - 0.057 12.4 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 GAP84722.1 - 0.26 12.1 1.2 1.1 10.0 0.1 2.4 2 1 0 2 2 2 0 AAA domain Methyltransf_2 PF00891.13 GAP84723.1 - 9.8e-28 96.9 0.0 2.8e-27 95.4 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_18 PF12847.2 GAP84723.1 - 0.0029 18.1 0.0 0.01 16.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain HTH_15 PF12324.3 GAP84723.1 - 0.0095 15.5 0.0 0.03 13.9 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain of alkylmercury lyase Sigma70_r3 PF04539.11 GAP84723.1 - 0.028 14.3 0.0 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 Sigma-70 region 3 zf-DHHC PF01529.15 GAP84724.1 - 0.0027 17.1 1.0 0.0044 16.4 0.7 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF4231 PF14015.1 GAP84724.1 - 0.014 15.3 1.6 0.029 14.3 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Ank_2 PF12796.2 GAP84725.1 - 4.8e-163 530.0 44.0 2.1e-17 63.1 0.7 13.5 4 3 10 15 15 15 15 Ankyrin repeats (3 copies) Ank PF00023.25 GAP84725.1 - 1.1e-129 416.2 42.0 5.4e-08 32.2 0.0 26.3 26 0 0 26 26 26 23 Ankyrin repeat Ank_4 PF13637.1 GAP84725.1 - 3.3e-110 358.7 24.9 1e-12 48.2 0.0 17.5 11 3 8 19 19 19 19 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP84725.1 - 6.7e-103 334.4 41.9 9.8e-08 32.0 0.1 22.3 7 6 15 22 22 22 21 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP84725.1 - 1.1e-98 313.1 20.4 4.6e-05 23.2 0.0 25.8 25 1 1 26 26 25 21 Ankyrin repeat NACHT PF05729.7 GAP84725.1 - 2.9e-07 30.2 0.0 4.3e-06 26.4 0.0 2.8 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 GAP84725.1 - 0.0016 18.4 0.3 0.0069 16.3 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAP84725.1 - 0.0042 17.2 0.0 0.018 15.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAP84725.1 - 0.0061 17.3 0.0 0.047 14.5 0.0 2.6 1 1 0 2 2 2 1 AAA domain PGAP1 PF07819.8 GAP84725.1 - 0.011 15.3 0.0 0.027 14.0 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein AAA_14 PF13173.1 GAP84725.1 - 0.023 14.5 0.3 0.093 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Abhydrolase_5 PF12695.2 GAP84725.1 - 0.03 14.0 0.0 0.12 12.0 0.0 2.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Arch_ATPase PF01637.13 GAP84725.1 - 0.035 13.7 0.1 0.067 12.8 0.1 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA PF00004.24 GAP84725.1 - 0.12 12.5 0.0 0.39 10.9 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 GAP84725.1 - 0.15 10.9 0.0 0.4 9.5 0.0 1.8 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 MoCF_biosynth PF00994.19 GAP84726.1 - 4.3e-33 113.7 2.2 1.3e-23 83.0 0.2 2.9 3 0 0 3 3 3 2 Probable molybdopterin binding domain MoeA_N PF03453.12 GAP84726.1 - 5.4e-32 110.3 2.2 1.3e-31 109.1 1.5 1.7 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 GAP84726.1 - 7.5e-17 61.0 0.0 2.1e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) Pkinase PF00069.20 GAP84727.1 - 6.9e-30 104.0 0.1 1.4e-29 103.0 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP84727.1 - 2.5e-16 59.5 0.0 4e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 GAP84727.1 - 0.14 10.9 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF2235 PF09994.4 GAP84728.1 - 5.2e-55 186.7 0.0 8.1e-55 186.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 GAP84728.1 - 0.063 13.0 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Methyltransf_11 PF08241.7 GAP84729.1 - 3e-13 50.0 0.0 5.6e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP84729.1 - 3.6e-13 49.1 0.0 5.7e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 GAP84729.1 - 6.5e-13 48.5 0.0 1.1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP84729.1 - 2.9e-11 43.3 0.0 4.9e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP84729.1 - 1.4e-10 41.5 0.0 2.5e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP84729.1 - 1.7e-07 31.5 0.0 3.3e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP84729.1 - 2.1e-07 31.0 0.2 3.9e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 GAP84729.1 - 8.7e-06 25.4 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP84729.1 - 0.00021 21.8 0.0 0.00039 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAP84729.1 - 0.00048 19.5 0.0 0.00083 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FmrO PF07091.6 GAP84729.1 - 0.0093 14.9 0.0 0.028 13.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) DUF2781 PF10914.3 GAP84731.1 - 1.4e-28 99.5 9.0 1.7e-28 99.3 6.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Tannase PF07519.6 GAP84734.1 - 5.4e-127 424.3 5.9 6.7e-127 424.0 4.1 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase IBV_3B PF03622.8 GAP84735.1 - 0.15 12.0 0.1 6.2 6.8 0.2 2.3 2 0 0 2 2 2 0 IBV 3B protein U-box PF04564.10 GAP84736.1 - 8.4e-18 64.1 0.0 1.5e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 GAP84736.1 - 3.6e-14 52.1 5.9 3.4e-12 45.8 1.1 2.6 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 GAP84736.1 - 0.0019 18.0 1.9 0.68 9.9 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAP84736.1 - 0.0074 16.9 0.4 7 7.4 0.0 3.0 2 1 2 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 GAP84736.1 - 0.021 14.9 1.8 0.021 14.9 1.2 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 GAP84736.1 - 0.15 12.2 1.1 2.8 8.3 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat CFEM PF05730.6 GAP84737.1 - 3e-07 30.1 6.5 4.9e-07 29.4 4.5 1.3 1 0 0 1 1 1 1 CFEM domain TctB PF07331.6 GAP84738.1 - 1.2 8.7 5.7 0.25 11.0 0.3 2.4 3 0 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family HET PF06985.6 GAP84739.1 - 2.4e-07 30.9 1.4 1.4e-05 25.2 0.1 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Nucleoporin_C PF03177.9 GAP84740.1 - 2.5e-122 409.3 0.9 3.4e-122 408.9 0.7 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 GAP84740.1 - 3.1e-81 273.3 0.1 4.1e-81 272.8 0.1 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Utp12 PF04003.7 GAP84740.1 - 0.088 12.7 0.0 8.1 6.3 0.0 3.3 3 0 0 3 3 3 0 Dip2/Utp12 Family adh_short PF00106.20 GAP84741.1 - 7.6e-23 81.2 0.0 1e-22 80.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP84741.1 - 1.8e-08 34.4 0.0 2.6e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP84741.1 - 6.2e-07 29.2 0.0 9.1e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAP84741.1 - 0.00059 19.8 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Glyco_tran_WecB PF03808.8 GAP84741.1 - 0.0039 16.6 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase WecB/TagA/CpsF family Polysacc_synt_2 PF02719.10 GAP84741.1 - 0.0091 14.9 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF239 PF03080.10 GAP84741.1 - 0.11 11.6 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF239) Erg28 PF03694.8 GAP84742.1 - 1.1e-38 131.7 0.2 1.3e-38 131.4 0.1 1.1 1 0 0 1 1 1 1 Erg28 like protein GalP_UDP_transf PF01087.17 GAP84743.1 - 2.2e-68 229.9 0.2 2.7e-66 223.0 0.1 2.2 2 0 0 2 2 2 2 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 GAP84743.1 - 1.1e-56 190.9 0.0 1.8e-56 190.2 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 GAP84743.1 - 0.016 15.7 0.0 0.055 13.9 0.0 1.9 2 0 0 2 2 2 0 HIT domain TRAP-gamma PF07074.7 GAP84743.1 - 0.061 12.8 0.0 0.09 12.3 0.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) SWIRM PF04433.12 GAP84744.1 - 9.4e-12 44.8 0.0 2.7e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 GAP84744.1 - 9.7e-11 41.0 4.6 1.7e-10 40.2 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 GAP84744.1 - 1.2e-06 28.4 0.0 3.5e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-C3HC4_2 PF13923.1 GAP84744.1 - 1.2 9.1 5.1 2.8 8.0 3.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) O-FucT PF10250.4 GAP84745.1 - 1.3e-12 47.5 0.2 5e-11 42.3 0.1 2.7 2 1 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase YbaJ PF10757.4 GAP84745.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Biofilm formation regulator YbaJ DUF4319 PF14203.1 GAP84745.1 - 1.8 8.1 4.1 1.1 8.9 1.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4319) Rhodanese PF00581.15 GAP84746.1 - 8.3e-12 45.4 0.0 2e-11 44.2 0.0 1.6 1 1 0 1 1 1 1 Rhodanese-like domain CRAL_TRIO_2 PF13716.1 GAP84746.1 - 0.088 12.7 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Med13_C PF06333.7 GAP84747.1 - 1.8 7.0 5.1 2.1 6.7 3.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal TMEM154 PF15102.1 GAP84747.1 - 1.8 8.2 14.4 1.2e+02 2.3 10.0 2.9 1 1 0 1 1 1 0 TMEM154 protein family ORC6 PF05460.8 GAP84747.1 - 2.7 6.9 14.2 3.6 6.6 9.8 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Methyltransf_2 PF00891.13 GAP84748.1 - 5.4e-29 101.0 0.0 6.8e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 GAP84748.1 - 0.013 15.3 0.3 0.037 13.8 0.1 2.0 2 0 0 2 2 2 0 Dimerisation domain AMP-binding PF00501.23 GAP84749.1 - 1.6e-49 168.4 0.0 2.2e-49 168.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 GAP84749.1 - 9.7e-29 101.2 0.0 2.3e-28 99.9 0.0 1.7 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 GAP84749.1 - 5.7e-13 48.9 0.1 5.7e-13 48.9 0.1 2.3 3 0 0 3 3 3 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 GAP84749.1 - 8.6e-06 25.7 0.1 2e-05 24.6 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Aldo_ket_red PF00248.16 GAP84750.1 - 1.1e-48 165.5 0.0 1.3e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.27 GAP84751.1 - 4.8e-20 70.6 1.8 2.5e-05 23.9 0.0 5.3 6 0 0 6 6 6 4 WD domain, G-beta repeat BNR PF02012.15 GAP84751.1 - 0.12 12.3 0.9 0.42 10.6 0.1 2.4 2 0 0 2 2 2 0 BNR/Asp-box repeat Glyco_hydro_75 PF07335.6 GAP84752.1 - 6.2e-43 146.3 0.1 7.9e-43 146.0 0.1 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 TIP_N PF12457.3 GAP84752.1 - 0.16 12.0 0.2 0.28 11.2 0.1 1.3 1 0 0 1 1 1 0 Tuftelin interacting protein N terminal MFS_1 PF07690.11 GAP84753.1 - 2.9e-43 147.9 34.3 2.9e-43 147.9 23.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP84753.1 - 6e-13 48.1 20.0 8.9e-13 47.6 13.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 GAP84753.1 - 0.019 13.0 4.0 0.95 7.4 0.9 2.2 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Cutinase PF01083.17 GAP84754.1 - 6.3e-32 110.7 5.5 8.6e-32 110.3 3.8 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 GAP84754.1 - 0.0042 16.5 1.3 0.016 14.6 0.0 2.0 1 1 1 2 2 2 1 PE-PPE domain VirJ PF06057.6 GAP84754.1 - 0.02 14.7 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF3453 PF11935.3 GAP84756.1 - 2.3e-67 226.8 0.0 3.7e-67 226.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) XPA_C PF05181.7 GAP84756.1 - 0.011 15.2 0.1 0.026 14.0 0.1 1.6 1 0 0 1 1 1 0 XPA protein C-terminus Coiled-coil_56 PF09813.4 GAP84757.1 - 0.0042 17.0 0.0 0.0042 17.0 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 Sds3 PF08598.6 GAP84758.1 - 6.4e-25 87.8 4.1 6.4e-25 87.8 2.9 3.7 2 2 0 2 2 2 1 Sds3-like Glyco_hydro_47 PF01532.15 GAP84759.1 - 4.4e-163 543.1 0.0 5.1e-163 542.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Asp PF00026.18 GAP84760.1 - 0.0021 17.3 0.0 0.0057 15.9 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease DUF2353 PF09789.4 GAP84762.1 - 4.2e-05 22.9 2.1 6.8e-05 22.2 1.5 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) ADIP PF11559.3 GAP84762.1 - 0.00045 20.1 2.0 0.00045 20.1 1.4 2.0 3 0 0 3 3 1 1 Afadin- and alpha -actinin-Binding ATG16 PF08614.6 GAP84762.1 - 0.0006 19.6 3.0 0.0006 19.6 2.1 2.2 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Mod_r PF07200.8 GAP84762.1 - 0.014 15.3 2.3 0.014 15.3 1.6 1.9 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF972 PF06156.8 GAP84762.1 - 0.054 13.8 8.1 0.058 13.7 1.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF972) TMF_DNA_bd PF12329.3 GAP84762.1 - 0.11 12.3 7.5 0.047 13.4 2.7 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 GAP84762.1 - 0.11 12.0 6.6 0.27 10.7 2.4 2.7 3 0 0 3 3 3 0 Septum formation initiator FliD_C PF07195.7 GAP84762.1 - 0.19 11.0 4.3 0.6 9.3 3.0 1.8 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Herpes_UL6 PF01763.11 GAP84762.1 - 0.19 9.8 0.2 0.3 9.1 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like DivIVA PF05103.8 GAP84762.1 - 0.25 11.4 9.3 0.43 10.6 0.9 2.8 3 0 0 3 3 3 0 DivIVA protein Ax_dynein_light PF10211.4 GAP84762.1 - 0.3 10.9 3.9 0.27 11.0 1.0 2.0 2 0 0 2 2 2 0 Axonemal dynein light chain Cep57_CLD_2 PF14197.1 GAP84762.1 - 0.9 9.5 8.9 0.29 11.1 3.3 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 bZIP_2 PF07716.10 GAP84762.1 - 1.1 9.1 8.6 1.9 8.3 0.9 2.9 2 1 1 3 3 3 0 Basic region leucine zipper TMF_TATA_bd PF12325.3 GAP84762.1 - 1.2 8.8 7.4 0.066 12.9 0.7 2.1 3 0 0 3 3 2 0 TATA element modulatory factor 1 TATA binding bZIP_1 PF00170.16 GAP84762.1 - 1.3 9.0 10.3 4 7.4 2.8 2.8 2 1 0 2 2 2 0 bZIP transcription factor PilJ PF13675.1 GAP84762.1 - 1.3 9.3 9.0 0.31 11.3 1.3 3.1 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF904 PF06005.7 GAP84762.1 - 2.3 8.5 13.3 0.064 13.5 4.0 2.3 3 0 0 3 3 2 0 Protein of unknown function (DUF904) IncA PF04156.9 GAP84762.1 - 8.5 5.9 8.2 0.21 11.1 0.9 1.9 2 1 0 2 2 2 0 IncA protein GMC_oxred_N PF00732.14 GAP84765.1 - 3.3e-27 95.4 0.1 5.8e-27 94.6 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAP84765.1 - 6.8e-24 84.7 0.4 1.3e-23 83.9 0.3 1.5 1 0 0 1 1 1 1 GMC oxidoreductase CBM_1 PF00734.13 GAP84765.1 - 4.3e-10 39.0 14.0 1.2e-09 37.6 9.7 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain FAD_binding_2 PF00890.19 GAP84765.1 - 9e-09 34.6 0.3 0.00022 20.1 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAP84765.1 - 5.5e-08 32.1 0.2 4.7e-05 22.4 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAP84765.1 - 9.1e-05 22.4 0.1 0.00029 20.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAP84765.1 - 0.0006 19.9 0.2 0.0049 16.9 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAP84765.1 - 0.0016 16.9 0.1 0.0025 16.3 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 GAP84765.1 - 0.0027 17.6 0.0 0.0053 16.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAP84765.1 - 0.006 15.7 0.7 0.013 14.5 0.5 1.5 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 GAP84765.1 - 0.0063 15.6 0.0 0.18 10.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAP84765.1 - 0.057 12.3 0.1 0.086 11.7 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 GAP84765.1 - 0.059 12.4 0.1 0.099 11.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 GAP84765.1 - 0.086 13.2 0.1 0.33 11.3 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mpv17_PMP22 PF04117.7 GAP84766.1 - 2e-16 59.3 0.3 5e-16 58.0 0.2 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family Ank_2 PF12796.2 GAP84767.1 - 5.9e-37 125.8 12.6 3.2e-08 33.7 0.0 8.6 4 3 4 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 GAP84767.1 - 1.9e-20 71.5 20.3 3.6e-05 23.3 0.0 13.1 12 2 0 12 12 12 4 Ankyrin repeat Ank_4 PF13637.1 GAP84767.1 - 1.5e-16 60.4 8.5 6.1e-05 23.4 0.0 9.7 8 2 1 9 9 9 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP84767.1 - 3e-13 49.5 7.6 3.9e-06 26.9 0.0 8.1 7 1 1 8 8 8 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP84767.1 - 5.4e-12 44.7 11.0 0.32 11.3 0.0 13.4 15 1 1 16 16 16 2 Ankyrin repeat Ank_2 PF12796.2 GAP84768.1 - 1e-22 80.2 8.8 0.00013 22.2 0.0 5.9 2 2 5 7 7 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAP84768.1 - 8.7e-13 47.1 7.0 3.2 8.2 0.0 10.0 12 0 0 12 12 12 4 Ankyrin repeat Ank PF00023.25 GAP84768.1 - 1.5e-09 37.1 11.6 0.39 10.6 0.0 8.8 11 0 0 11 11 11 3 Ankyrin repeat Ank_5 PF13857.1 GAP84768.1 - 5.4e-08 32.8 6.0 1.1 9.6 0.0 7.9 7 3 3 10 10 10 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAP84768.1 - 1.7e-07 31.5 2.6 1.1 9.8 0.0 6.4 7 1 1 8 8 8 2 Ankyrin repeats (many copies) Epimerase PF01370.16 GAP84769.1 - 1.7e-46 158.5 0.0 2.2e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 GAP84769.1 - 1.6e-24 85.5 0.0 3.2e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 GAP84769.1 - 2.2e-16 59.4 0.0 6.4e-16 57.8 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 GAP84769.1 - 2.2e-12 46.4 0.0 3.3e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 GAP84769.1 - 1.5e-11 43.7 0.0 7.7e-10 38.1 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 GAP84769.1 - 5.4e-10 39.4 0.1 8.2e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 GAP84769.1 - 7e-09 34.9 0.0 2.9e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 GAP84769.1 - 3.6e-08 33.6 0.0 6.8e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 GAP84769.1 - 7.2e-06 25.7 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 KR domain UDPG_MGDP_dh_N PF03721.9 GAP84769.1 - 0.0052 16.1 0.1 0.01 15.2 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.8 GAP84769.1 - 0.0071 15.6 0.0 0.031 13.5 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family DAO PF01266.19 GAP84769.1 - 0.12 11.2 0.4 0.2 10.5 0.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Sad1_UNC PF07738.8 GAP84770.1 - 1.6e-07 31.1 0.1 5e-07 29.5 0.1 1.9 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal Rho_Binding PF08912.6 GAP84770.1 - 0.73 10.1 5.6 2.3 8.5 0.3 2.6 2 0 0 2 2 2 0 Rho Binding bZIP_1 PF00170.16 GAP84770.1 - 5.5 7.0 5.4 8.6 6.3 0.3 2.5 2 0 0 2 2 2 0 bZIP transcription factor DEAD PF00270.24 GAP84771.1 - 1.5e-43 148.1 0.0 2.6e-43 147.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 GAP84771.1 - 3.1e-23 81.0 0.3 6.6e-23 80.0 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 GAP84771.1 - 5.8e-18 64.5 0.0 1.4e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAP84771.1 - 0.00039 20.3 1.2 0.0065 16.3 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 GAP84771.1 - 0.0014 18.6 0.0 0.005 16.8 0.0 1.9 1 1 0 1 1 1 1 Helicase C-terminal domain GMC_oxred_N PF00732.14 GAP84772.1 - 3.2e-50 170.9 0.0 4.4e-50 170.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAP84772.1 - 1.3e-38 132.4 0.0 2.1e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAP84772.1 - 5.1e-06 25.6 0.1 0.00016 20.7 0.0 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAP84772.1 - 3.2e-05 23.0 0.1 5.1e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 GAP84772.1 - 8.4e-05 22.5 0.1 0.00027 20.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAP84772.1 - 0.00034 19.6 0.0 0.026 13.3 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 GAP84772.1 - 0.006 15.2 0.1 0.0091 14.6 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 GAP84772.1 - 0.021 14.7 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAP84772.1 - 0.029 14.1 0.0 0.08 12.7 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 GAP84772.1 - 0.061 12.3 0.2 5.2 6.0 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAP84772.1 - 0.08 13.3 0.0 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAP84772.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Aldedh PF00171.17 GAP84773.1 - 2.6e-153 510.6 0.1 3.3e-153 510.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HAUS6_N PF14661.1 GAP84774.1 - 3.3e-55 187.1 0.0 3.3e-55 187.1 0.0 1.9 3 0 0 3 3 3 1 HAUS augmin-like complex subunit 6 N-terminus Corona_RPol_N PF06478.8 GAP84776.1 - 0.18 10.4 0.4 0.49 9.0 0.0 1.7 2 0 0 2 2 2 0 Coronavirus RPol N-terminus Pyr_redox_2 PF07992.9 GAP84777.1 - 1.8e-10 41.0 0.0 1.2e-08 35.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAP84777.1 - 0.0045 15.9 3.2 0.048 12.5 0.5 2.8 2 1 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.14 GAP84777.1 - 0.018 14.1 0.8 0.04 12.9 0.6 1.6 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 GAP84777.1 - 0.17 10.7 1.8 0.21 10.4 1.2 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase FNIP_N PF14636.1 GAP84778.1 - 2.5e-26 92.7 0.1 2.5e-26 92.7 0.1 4.6 4 1 1 5 5 5 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.1 GAP84778.1 - 0.034 13.7 0.2 0.83 9.1 0.1 2.6 2 1 1 3 3 3 0 Folliculin-interacting protein middle domain PHP PF02811.14 GAP84779.1 - 2.7e-09 37.0 0.0 9.9e-09 35.2 0.0 1.8 2 0 0 2 2 2 1 PHP domain Med3 PF11593.3 GAP84779.1 - 0.0093 15.2 5.6 0.012 14.8 3.9 1.1 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal MSP1_C PF07462.6 GAP84779.1 - 2.8 6.2 7.5 3.9 5.7 5.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus SSP160 PF06933.6 GAP84779.1 - 4.8 5.0 14.4 6.4 4.6 10.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RRM_5 PF13893.1 GAP84780.1 - 7.3e-11 41.7 0.3 2e-10 40.3 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP84780.1 - 3.7e-10 39.6 0.1 1.3e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAP84780.1 - 6.7e-08 32.0 0.5 2.9e-07 30.0 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 GAP84780.1 - 5.9e-05 22.6 4.5 0.00011 21.7 3.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PWI PF01480.12 GAP84780.1 - 0.00012 22.0 0.0 0.00029 20.8 0.0 1.6 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.1 GAP84780.1 - 0.00031 20.4 0.0 0.03 14.0 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DUF1330 PF07045.6 GAP84780.1 - 0.0068 16.2 0.1 0.02 14.7 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1330) RRM_3 PF08777.6 GAP84780.1 - 0.083 12.7 0.1 0.083 12.7 0.0 3.2 3 0 0 3 3 3 0 RNA binding motif HrpJ PF07201.6 GAP84780.1 - 2.7 7.9 11.9 3.2 7.7 7.4 1.7 2 0 0 2 2 2 0 HrpJ-like domain DUF4407 PF14362.1 GAP84780.1 - 8.1 5.3 7.1 14 4.5 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cation_efflux PF01545.16 GAP84782.1 - 3.5e-74 249.4 9.5 4.1e-74 249.2 6.6 1.0 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.11 GAP84782.1 - 0.003 16.5 1.1 0.003 16.5 0.7 2.1 2 1 0 2 2 2 1 Branched-chain amino acid transport system / permease component adh_short PF00106.20 GAP84783.1 - 1.1e-17 64.5 0.6 1.7e-17 63.8 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP84783.1 - 5.4e-08 32.9 0.0 8.8e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP84783.1 - 1e-07 31.7 0.4 3.8e-07 29.9 0.1 1.9 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 GAP84783.1 - 0.0012 18.3 0.2 0.0018 17.7 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAP84783.1 - 0.0058 15.5 0.1 0.0093 14.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Heme_oxygenase PF01126.15 GAP84783.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Heme oxygenase DUF3608 PF12257.3 GAP84784.1 - 1.5e-72 243.8 0.0 3.7e-72 242.5 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 GAP84784.1 - 7.9e-30 102.4 0.2 1.6e-29 101.4 0.2 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Na_Ca_ex PF01699.19 GAP84785.1 - 3.4e-42 143.3 31.3 1.8e-21 76.2 7.2 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Tad PF13400.1 GAP84785.1 - 0.11 12.5 10.5 1.6 8.8 0.1 3.8 3 0 0 3 3 3 0 Putative Flp pilus-assembly TadE/G-like ATP-synt_8 PF00895.15 GAP84785.1 - 0.19 11.9 0.6 0.96 9.6 0.1 2.5 2 0 0 2 2 2 0 ATP synthase protein 8 DUF1673 PF07895.6 GAP84785.1 - 2.2 7.7 4.4 0.41 10.1 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) PTR2 PF00854.16 GAP84786.1 - 2.3e-24 85.9 5.4 6.7e-12 44.8 1.9 2.2 2 0 0 2 2 2 2 POT family Clp1 PF06807.9 GAP84788.1 - 6.3e-25 88.0 0.0 1e-24 87.3 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MMR_HSR1 PF01926.18 GAP84788.1 - 1.5e-06 28.1 0.1 1.1e-05 25.3 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.9 GAP84788.1 - 2.6e-06 27.1 0.0 1.1e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 GAP84788.1 - 0.00022 20.8 0.0 0.0005 19.6 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 GAP84788.1 - 0.0014 18.6 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 GAP84788.1 - 0.0078 15.6 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain ArgK PF03308.11 GAP84788.1 - 0.039 12.7 0.1 0.081 11.6 0.0 1.5 2 0 0 2 2 2 0 ArgK protein Parvo_NS1 PF01057.12 GAP84788.1 - 0.042 12.7 0.0 0.064 12.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KTI12 PF08433.5 GAP84788.1 - 0.06 12.5 0.0 0.98 8.5 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 FeoB_N PF02421.13 GAP84788.1 - 0.15 11.3 0.0 0.61 9.3 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B IPK PF03770.11 GAP84789.1 - 1.3e-47 162.0 0.0 1.8e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Arb1 PF09692.5 GAP84790.1 - 3.4e-103 345.5 0.0 4.9e-103 345.0 0.0 1.2 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Hist_deacetyl PF00850.14 GAP84791.1 - 2e-62 211.2 0.3 3e-62 210.6 0.2 1.2 1 0 0 1 1 1 1 Histone deacetylase domain ParA PF10609.4 GAP84792.1 - 1.8e-34 117.4 0.0 3.7e-34 116.4 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 GAP84792.1 - 1.1e-15 57.5 0.0 1.6e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 GAP84792.1 - 0.00034 20.5 0.0 0.0011 18.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 GAP84792.1 - 0.001 18.5 0.1 0.0019 17.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAP84792.1 - 0.0028 17.3 1.8 0.47 10.2 1.0 2.6 2 0 0 2 2 2 1 Part of AAA domain ArsA_ATPase PF02374.10 GAP84792.1 - 0.0044 16.1 1.7 0.029 13.4 1.1 2.1 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_26 PF13500.1 GAP84792.1 - 0.0088 15.6 0.1 0.64 9.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 GAP84792.1 - 0.022 13.9 0.0 0.041 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 GAP84792.1 - 0.079 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase MipZ PF09140.6 GAP84792.1 - 0.081 11.9 0.0 0.19 10.8 0.0 1.7 1 1 0 1 1 1 0 ATPase MipZ AAA_17 PF13207.1 GAP84792.1 - 0.085 13.6 0.2 0.16 12.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 GAP84792.1 - 0.16 11.9 0.2 0.66 9.9 0.2 1.8 2 0 0 2 2 2 0 AAA ATPase domain Cofilin_ADF PF00241.15 GAP84793.1 - 1.4e-08 34.7 0.0 1.8e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Glyco_hydro_43 PF04616.9 GAP84794.1 - 4.4e-43 147.4 3.7 5e-43 147.2 2.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 HTH_Tnp_Tc5 PF03221.11 GAP84795.1 - 1.4e-17 63.2 5.8 3.3e-06 26.7 0.0 6.3 5 1 0 5 5 5 4 Tc5 transposase DNA-binding domain Homeobox_KN PF05920.6 GAP84795.1 - 3.9e-15 55.2 1.8 2.6e-14 52.6 0.6 3.0 3 0 0 3 3 3 1 Homeobox KN domain Homeobox PF00046.24 GAP84795.1 - 4.9e-05 22.8 0.2 0.00011 21.7 0.2 1.6 1 0 0 1 1 1 1 Homeobox domain zf-C2H2 PF00096.21 GAP84795.1 - 0.00055 20.1 13.3 0.034 14.4 2.6 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP84795.1 - 0.015 15.5 4.2 0.015 15.5 2.9 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger Zn_clus PF00172.13 GAP84795.1 - 2.8 7.9 9.1 0.77 9.7 1.8 2.5 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PAN_4 PF14295.1 GAP84797.1 - 0.045 13.4 1.2 3.7 7.3 0.0 2.6 2 0 0 2 2 2 0 PAN domain DUF3425 PF11905.3 GAP84798.1 - 1e-22 80.4 1.5 1.8e-22 79.6 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Shisa PF13908.1 GAP84799.1 - 0.0035 17.5 0.1 0.0038 17.4 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator MTHFR PF02219.12 GAP84800.1 - 7e-110 366.6 0.0 1.1e-109 366.0 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase MoCF_biosynth PF00994.19 GAP84801.1 - 1.9e-35 121.3 0.0 2.9e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Ras PF00071.17 GAP84802.1 - 1.1e-54 184.1 0.1 1.3e-54 183.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAP84802.1 - 3.1e-18 66.3 0.0 4.4e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAP84802.1 - 1.1e-06 28.0 0.0 1.2e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAP84802.1 - 0.00023 20.6 0.2 0.0013 18.1 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAP84802.1 - 0.0059 15.7 0.1 0.0077 15.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAP84802.1 - 0.0061 16.5 0.0 0.0082 16.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 GAP84802.1 - 0.087 12.0 0.1 0.21 10.7 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Ldh_1_N PF00056.18 GAP84802.1 - 0.13 12.0 0.0 0.42 10.4 0.0 1.8 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Zn_clus PF00172.13 GAP84803.1 - 0.0035 17.2 4.6 0.0035 17.2 3.2 3.6 3 1 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 GAP84805.1 - 8.8e-07 28.7 12.5 1.4e-06 28.0 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4656 PF15551.1 GAP84805.1 - 0.21 10.7 1.1 0.32 10.1 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4656) adh_short PF00106.20 GAP84806.1 - 1.1e-18 67.7 3.2 1.6e-18 67.1 2.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP84806.1 - 7.6e-12 45.2 1.2 1.1e-11 44.7 0.9 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAP84806.1 - 0.0002 21.2 0.0 0.00025 20.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 GAP84806.1 - 0.0036 16.2 0.0 0.0052 15.7 0.0 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 GAP84806.1 - 0.059 13.1 1.0 0.2 11.4 0.7 1.9 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase p450 PF00067.17 GAP84807.1 - 7.9e-77 258.7 0.0 9.7e-77 258.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1932 PF09130.6 GAP84808.1 - 5.3e-22 77.3 0.1 1.1e-21 76.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) F420_oxidored PF03807.12 GAP84808.1 - 3.7e-10 40.0 0.1 9.1e-10 38.8 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 GAP84808.1 - 7.7e-08 32.3 0.0 1.2e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 GAP84808.1 - 0.0018 17.4 0.0 0.0034 16.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 GAP84808.1 - 0.0081 15.8 0.1 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RRM_1 PF00076.17 GAP84809.1 - 5.8e-18 64.3 0.0 1.1e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP84809.1 - 5.5e-12 45.4 0.0 9.2e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP84809.1 - 7.4e-08 32.1 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 GAP84809.1 - 1.6e-06 28.4 6.4 1.6e-06 28.4 4.4 3.2 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 DUF2611 PF11022.3 GAP84810.1 - 0.088 12.9 0.1 7.1 6.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2611) SET PF00856.23 GAP84811.1 - 4.9e-13 49.7 0.0 5.6e-12 46.2 0.0 2.4 1 1 0 1 1 1 1 SET domain PI-PLC-X PF00388.14 GAP84812.1 - 4.1e-14 52.2 0.0 6.4e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain His_biosynth PF00977.16 GAP84812.1 - 0.081 12.1 0.0 0.2 10.8 0.0 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein DAGAT PF03982.8 GAP84813.1 - 1.4e-95 319.3 0.0 1.9e-95 318.9 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase TPT PF03151.11 GAP84814.1 - 2.6e-32 111.5 8.7 2.6e-32 111.5 6.0 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 GAP84814.1 - 5.9e-06 25.4 16.8 6.7e-06 25.2 11.2 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 GAP84814.1 - 0.0028 17.6 33.8 0.13 12.3 6.2 2.9 2 1 0 2 2 2 2 EamA-like transporter family SpoIIIAH PF12685.2 GAP84814.1 - 0.13 11.7 3.2 1.4 8.3 0.0 2.4 2 1 0 2 2 2 0 SpoIIIAH-like protein Herpes_LMP1 PF05297.6 GAP84814.1 - 0.21 10.4 0.0 0.21 10.4 0.0 3.5 4 0 0 4 4 4 0 Herpesvirus latent membrane protein 1 (LMP1) RRM_1 PF00076.17 GAP84815.1 - 3.9e-16 58.4 0.0 3.9e-16 58.4 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP84815.1 - 2.1e-10 40.4 0.0 4.2e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP84815.1 - 0.00028 20.6 1.6 0.0004 20.1 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 GAP84815.1 - 0.086 12.3 0.2 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain 6PGD PF00393.14 GAP84816.1 - 1.9e-134 447.4 0.0 2.3e-134 447.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 GAP84816.1 - 1.1e-52 178.2 0.0 1.7e-52 177.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 GAP84816.1 - 0.043 13.8 0.1 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PGK PF00162.14 GAP84816.1 - 0.066 11.7 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase SWI-SNF_Ssr4 PF08549.5 GAP84817.1 - 1.1e-192 641.9 10.9 1.3e-192 641.7 7.6 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Peptidase_M57 PF12388.3 GAP84817.1 - 0.12 11.7 2.1 0.18 11.1 0.2 2.0 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Metal_resist PF13801.1 GAP84817.1 - 1.6 8.6 9.3 0.047 13.6 1.1 2.4 2 0 0 2 2 2 0 Heavy-metal resistance RRM_1 PF00076.17 GAP84819.1 - 5.4e-12 45.1 0.0 1.8e-10 40.2 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP84819.1 - 1.3e-08 34.5 0.0 0.00082 19.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP84819.1 - 5e-08 32.8 0.0 4.7e-07 29.6 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SH3_2 PF07653.12 GAP84821.1 - 5.7e-10 38.5 0.0 1.2e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAP84821.1 - 1.4e-09 37.2 0.2 3e-09 36.1 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAP84821.1 - 9.4e-08 31.5 0.1 2.1e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain RPAP2_Rtr1 PF04181.8 GAP84822.1 - 1.9e-18 66.3 0.1 3.6e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family Zein-binding PF04576.10 GAP84822.1 - 0.14 12.2 2.8 0.26 11.4 1.9 1.4 1 0 0 1 1 1 0 Zein-binding Ribosomal_S17e PF00833.13 GAP84823.1 - 6.1e-56 187.4 0.1 7.6e-56 187.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 GAP84823.1 - 0.019 15.6 0.0 0.027 15.1 0.0 1.3 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal GUCT PF08152.7 GAP84823.1 - 0.06 13.3 0.0 0.082 12.8 0.0 1.2 1 0 0 1 1 1 0 GUCT (NUC152) domain Mit_ribos_Mrp51 PF11709.3 GAP84824.1 - 1.7e-75 254.1 0.0 2.1e-75 253.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit DUF1681 PF07933.9 GAP84825.1 - 4.5e-55 185.5 0.0 5.5e-55 185.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) TGT PF01702.13 GAP84827.1 - 1.6e-87 292.7 0.0 2e-87 292.4 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase p450 PF00067.17 GAP84828.1 - 3.1e-32 111.7 0.2 5.2e-32 110.9 0.1 1.3 1 0 0 1 1 1 1 Cytochrome P450 GCK PF07802.6 GAP84828.1 - 0.043 13.9 0.0 0.47 10.6 0.0 2.3 2 0 0 2 2 2 0 GCK domain DUF2034 PF10356.4 GAP84830.1 - 3.2e-28 98.1 0.0 2.7e-14 52.7 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 GAP84830.1 - 2e-08 34.0 0.0 3.2e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease Med21 PF11221.3 GAP84831.1 - 5.3e-44 149.6 10.6 5.9e-44 149.5 7.3 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.8 GAP84831.1 - 0.0019 17.9 8.8 0.022 14.4 1.6 2.7 1 1 1 2 2 2 2 RNA polymerase II transcription mediator complex subunit 9 Spore_III_AB PF09548.5 GAP84831.1 - 0.059 13.1 2.1 0.057 13.1 0.8 1.5 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) CENP-Q PF13094.1 GAP84831.1 - 0.059 13.3 7.6 0.025 14.6 3.8 1.5 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Cauli_AT PF03233.8 GAP84831.1 - 0.069 12.8 2.3 0.087 12.5 1.6 1.3 1 1 0 1 1 1 0 Aphid transmission protein CTP_transf_2 PF01467.21 GAP84831.1 - 0.097 12.7 0.7 0.19 11.7 0.5 1.6 1 1 0 1 1 1 0 Cytidylyltransferase DUF1640 PF07798.6 GAP84831.1 - 0.13 12.2 2.4 0.084 12.9 0.5 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) YebO PF13974.1 GAP84831.1 - 1.5 8.6 4.9 3.9 7.3 3.4 1.7 1 0 0 1 1 1 0 YebO-like protein Fib_alpha PF08702.5 GAP84831.1 - 1.6 8.8 5.4 3.5 7.7 3.1 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family AAA_16 PF13191.1 GAP84831.1 - 1.7 8.6 5.1 4.3 7.2 3.5 1.7 1 1 0 1 1 1 0 AAA ATPase domain APG6 PF04111.7 GAP84831.1 - 2.8 6.9 8.1 3.1 6.7 5.6 1.3 1 1 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.10 GAP84831.1 - 3.3 7.3 7.9 2.4 7.7 4.3 1.6 1 1 0 1 1 1 0 Mnd1 family HAD_2 PF13419.1 GAP84832.1 - 6.5e-35 120.9 0.0 7.9e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAP84832.1 - 4.7e-08 32.6 0.0 8.4e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 GAP84832.1 - 5.7e-08 33.4 0.0 1.6e-07 31.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAP84832.1 - 0.0016 18.6 0.0 0.0019 18.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 GAP84832.1 - 0.018 14.6 0.0 0.33 10.5 0.0 2.1 2 0 0 2 2 2 0 Acid Phosphatase 5_nucleotid PF05761.9 GAP84832.1 - 0.054 12.0 0.0 0.089 11.2 0.0 1.5 1 1 1 2 2 2 0 5' nucleotidase family DUF2664 PF10867.3 GAP84833.1 - 0.054 14.1 0.2 0.13 12.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2664) KH_1 PF00013.24 GAP84834.1 - 4.3e-30 103.1 6.9 1.3e-07 31.1 0.2 7.9 8 0 0 8 8 8 6 KH domain KH_3 PF13014.1 GAP84834.1 - 1.6e-29 100.9 4.2 1e-06 28.2 0.0 6.6 6 0 0 6 6 6 5 KH domain Peptidase_M16 PF00675.15 GAP84834.1 - 0.051 13.3 0.2 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) Acetyltransf_1 PF00583.19 GAP84835.1 - 3.6e-09 36.5 0.0 6.6e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAP84835.1 - 2.1e-07 30.9 0.1 3.7e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAP84835.1 - 0.00011 22.2 0.0 0.00027 21.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAP84835.1 - 0.0045 16.8 0.0 0.19 11.6 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAP84835.1 - 0.056 13.3 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Secretin_N_2 PF07655.8 GAP84835.1 - 2.6 8.4 15.0 1.8 8.9 7.9 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain Sigma70_ner PF04546.8 GAP84835.1 - 7.2 6.1 11.0 10 5.6 7.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region NOGCT PF08155.6 GAP84836.1 - 6e-28 96.3 0.3 1.6e-27 94.9 0.2 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 GAP84836.1 - 6.1e-27 93.2 0.5 1.4e-26 92.1 0.4 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 GAP84836.1 - 4.2e-13 49.2 0.0 8.5e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAP84836.1 - 7.7e-08 31.7 0.0 1.4e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 GAP84836.1 - 0.00067 18.8 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.18 GAP84836.1 - 0.002 17.9 1.1 1.7 8.4 0.0 2.9 2 1 1 3 3 3 2 Dynamin family Miro PF08477.8 GAP84836.1 - 0.0043 17.5 0.0 0.0092 16.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 GAP84836.1 - 0.015 15.4 0.0 0.65 10.1 0.0 2.8 1 1 1 2 2 2 0 AAA domain Ras PF00071.17 GAP84836.1 - 0.084 12.2 0.0 0.15 11.4 0.0 1.5 1 1 0 1 1 1 0 Ras family PPV_E1_C PF00519.12 GAP84836.1 - 0.14 10.7 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase FtsK_SpoIIIE PF01580.13 GAP84836.1 - 0.3 10.5 3.7 4.5 6.6 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family Pribosyltran PF00156.22 GAP84837.1 - 1.8e-19 69.6 0.3 3.3e-19 68.8 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Fungal_trans PF04082.13 GAP84838.1 - 2.2e-14 52.9 0.1 4.2e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 GAP84838.1 - 1.1e-07 31.8 6.7 1.3e-05 25.2 0.8 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAP84838.1 - 4e-05 23.6 14.2 0.0015 18.6 4.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 GAP84838.1 - 0.0015 18.6 3.8 0.003 17.6 2.6 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 GAP84838.1 - 0.26 11.7 21.2 0.051 13.9 4.7 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-BED PF02892.10 GAP84838.1 - 2.9 7.7 7.8 1.2 8.9 0.9 2.5 2 0 0 2 2 2 0 BED zinc finger MRP-L47 PF06984.8 GAP84839.1 - 2.8e-22 78.3 0.3 5.1e-22 77.5 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) GDI PF00996.13 GAP84840.1 - 4.4e-183 608.5 0.0 5e-183 608.3 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 GAP84840.1 - 0.024 14.6 0.0 0.06 13.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain IF-2B PF01008.12 GAP84841.1 - 6.9e-39 133.5 0.1 1.1e-38 132.9 0.0 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family RepL PF05732.6 GAP84841.1 - 0.00048 19.3 0.0 0.0011 18.1 0.0 1.6 1 0 0 1 1 1 1 Firmicute plasmid replication protein (RepL) Methyltransf_33 PF10017.4 GAP84842.1 - 4.1e-31 107.4 0.0 8.3e-31 106.5 0.0 1.5 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 GAP84842.1 - 4.7e-20 72.0 0.8 1.5e-10 40.8 0.1 2.2 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 GAP84842.1 - 1.3e-06 28.7 0.3 3.1e-06 27.5 0.2 1.7 1 0 0 1 1 1 1 DinB superfamily Methyltransf_25 PF13649.1 GAP84842.1 - 0.049 14.0 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Asp_protease PF09668.5 GAP84843.1 - 9.7e-56 186.6 0.4 1.5e-55 186.0 0.3 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 GAP84843.1 - 1.1e-10 41.8 0.1 3.5e-10 40.2 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 GAP84843.1 - 2.6e-07 30.3 0.0 7e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UBA PF00627.26 GAP84843.1 - 3.8e-07 29.7 0.0 1.2e-06 28.1 0.0 2.0 1 0 0 1 1 1 1 UBA/TS-N domain RVP PF00077.15 GAP84843.1 - 6.2e-07 29.2 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease ubiquitin PF00240.18 GAP84843.1 - 6.6e-07 28.6 0.0 1.4e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family RVP_2 PF08284.6 GAP84843.1 - 1.4e-05 25.0 0.0 2.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.1 GAP84843.1 - 0.003 17.0 0.3 0.0069 15.8 0.2 1.6 1 0 0 1 1 1 1 UBA-like domain Sporozoite_P67 PF05642.6 GAP84843.1 - 0.085 10.7 1.4 0.11 10.2 1.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Rad60-SLD PF11976.3 GAP84843.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Methyltransf_8 PF05148.10 GAP84844.1 - 1.5e-57 194.7 0.0 1.7e-55 188.0 0.0 2.4 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 GAP84844.1 - 5.1e-06 26.8 0.0 1.5e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 GAP84844.1 - 0.0032 17.1 0.0 0.0081 15.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP84844.1 - 0.0036 16.8 0.0 2.5 7.6 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.9 GAP84844.1 - 0.089 12.1 0.0 3.5 6.9 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase small domain Fungal_trans_2 PF11951.3 GAP84845.1 - 3.1e-20 72.1 1.9 3.1e-18 65.5 1.3 2.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP84845.1 - 3.8e-08 33.1 12.0 6.7e-08 32.3 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAP84845.1 - 3.1e-05 23.0 1.0 0.0021 16.9 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Proteasome PF00227.21 GAP84847.1 - 6.7e-57 191.8 0.2 8.4e-57 191.5 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 GAP84847.1 - 1e-13 50.3 0.0 2.2e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3137 PF11335.3 GAP84847.1 - 0.011 15.4 0.1 0.27 10.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) Spc97_Spc98 PF04130.8 GAP84848.1 - 2e-130 435.6 5.0 2.9e-130 435.1 3.5 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family YqeY PF09424.5 GAP84849.1 - 1.1e-21 77.2 0.9 1.3e-21 76.9 0.6 1.1 1 0 0 1 1 1 1 Yqey-like protein Methyltransf_23 PF13489.1 GAP84850.1 - 4.3e-13 49.2 0.1 7.1e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP84850.1 - 1.9e-08 34.6 0.0 5.4e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP84850.1 - 4.3e-08 32.8 0.0 1.7e-07 30.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP84850.1 - 0.0001 22.6 0.0 0.00045 20.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP84850.1 - 0.00017 21.8 0.0 0.00046 20.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAP84850.1 - 0.00046 19.3 0.0 0.0008 18.5 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 GAP84850.1 - 0.00096 19.7 0.0 0.013 16.0 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 GAP84850.1 - 0.0024 17.8 0.1 0.096 12.6 0.0 2.7 1 1 1 2 2 2 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 GAP84850.1 - 0.017 14.2 0.0 0.067 12.2 0.0 2.0 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 GAP84850.1 - 0.019 15.0 0.0 0.1 12.6 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain PI3_PI4_kinase PF00454.22 GAP84852.1 - 1.3e-39 136.0 0.0 2e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Zip PF02535.17 GAP84853.1 - 0.17 10.8 1.6 0.17 10.8 1.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1180 PF06679.7 GAP84854.1 - 0.29 10.9 1.6 0.39 10.6 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SNF2_N PF00176.18 GAP84855.1 - 1.9e-72 243.5 0.0 2.9e-72 243.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAP84855.1 - 1.1e-10 41.2 0.0 4.2e-10 39.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAP84855.1 - 4.2e-05 23.1 0.0 8.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 GAP84855.1 - 0.00028 20.5 3.4 0.00051 19.7 2.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 GAP84855.1 - 0.044 13.6 0.7 0.1 12.4 0.5 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 GAP84855.1 - 0.061 12.9 4.0 0.13 11.9 2.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAP84855.1 - 0.11 12.5 2.2 0.25 11.4 1.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAP84855.1 - 1.6 8.6 4.9 4.2 7.3 3.4 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FA_desaturase PF00487.19 GAP84856.1 - 2.6e-18 66.3 8.0 2.6e-18 66.3 5.6 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 GAP84856.1 - 1.5e-16 59.9 0.0 5.2e-16 58.2 0.0 2.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pkinase PF00069.20 GAP84857.1 - 3.4e-09 36.2 0.0 2.5e-08 33.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP84857.1 - 2.8e-07 29.8 0.0 1.1e-06 27.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 GAP84857.1 - 0.079 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Lon_C PF05362.8 GAP84858.1 - 4.7e-65 218.7 0.0 8.9e-65 217.8 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 GAP84858.1 - 1e-34 120.0 0.0 2.6e-34 118.7 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 GAP84858.1 - 4.7e-22 78.5 0.0 1.3e-21 77.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 GAP84858.1 - 1.1e-07 31.3 0.0 2.6e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 GAP84858.1 - 6.1e-07 29.2 0.0 1.4e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 GAP84858.1 - 6.2e-07 29.4 0.0 2.8e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 GAP84858.1 - 1.7e-05 24.9 0.0 0.00037 20.6 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 GAP84858.1 - 4.1e-05 22.4 0.0 8.7e-05 21.3 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.1 GAP84858.1 - 5.6e-05 23.2 1.6 0.0062 16.5 0.0 3.4 3 1 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 GAP84858.1 - 8.6e-05 23.3 0.0 0.00035 21.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 GAP84858.1 - 0.00018 20.6 0.0 0.0014 17.7 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus ClpB_D2-small PF10431.4 GAP84858.1 - 0.00069 19.4 3.6 0.0015 18.4 0.1 2.7 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_14 PF13173.1 GAP84858.1 - 0.004 17.0 0.0 0.016 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAP84858.1 - 0.0064 16.8 0.3 0.027 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain SKI PF01202.17 GAP84858.1 - 0.014 15.2 0.1 0.18 11.6 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase MobB PF03205.9 GAP84858.1 - 0.024 14.3 0.0 0.066 12.9 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B TIP49 PF06068.8 GAP84858.1 - 0.034 12.8 0.1 1.1 7.9 0.0 2.4 2 0 0 2 2 2 0 TIP49 C-terminus IstB_IS21 PF01695.12 GAP84858.1 - 0.035 13.5 0.1 0.093 12.1 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein ATP-synt_ab PF00006.20 GAP84858.1 - 0.042 13.3 0.1 0.25 10.8 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF258 PF03193.11 GAP84858.1 - 0.045 12.9 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 GAP84858.1 - 0.046 13.8 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 GAP84858.1 - 0.058 13.0 0.2 1 9.0 0.0 2.5 1 1 1 2 2 2 0 NTPase AAA_25 PF13481.1 GAP84858.1 - 0.07 12.5 0.0 0.19 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 GAP84858.1 - 0.11 12.8 0.7 0.72 10.1 0.0 2.5 2 0 0 2 2 2 0 ABC transporter ResIII PF04851.10 GAP84859.1 - 1e-22 80.8 0.0 2.3e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 GAP84859.1 - 9.6e-13 47.8 0.1 2.2e-12 46.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAP84859.1 - 1.7e-11 43.8 0.0 5.2e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.4 GAP84859.1 - 0.0048 15.9 0.4 0.011 14.7 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 GAP84859.1 - 0.04 14.0 0.1 0.29 11.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain DUF3107 PF11305.3 GAP84859.1 - 0.079 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3107) Aldo_ket_red PF00248.16 GAP84860.1 - 3.7e-65 219.5 0.3 4.2e-65 219.3 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3425 PF11905.3 GAP84861.1 - 3.2e-24 85.3 0.3 5.5e-24 84.5 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 GAP84861.1 - 2.5 8.1 11.3 4.1 7.4 7.9 1.2 1 0 0 1 1 1 0 bZIP transcription factor Myb_DNA-binding PF00249.26 GAP84862.1 - 0.0092 16.0 0.0 0.099 12.7 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain CENP-T PF15511.1 GAP84862.1 - 0.16 11.1 36.2 0.021 14.0 18.8 2.5 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T SWIRM PF04433.12 GAP84863.1 - 1.4e-33 114.8 0.1 2.7e-33 113.9 0.1 1.5 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 GAP84863.1 - 2.4e-08 33.8 0.0 4.9e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAP84863.1 - 3.1e-07 30.3 0.2 7.3e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3439 PF11921.3 GAP84863.1 - 0.051 13.3 0.5 0.1 12.3 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) ETF PF01012.16 GAP84864.1 - 5.6e-41 139.9 0.3 9.4e-41 139.2 0.2 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 GAP84864.1 - 1.7e-35 120.5 0.7 3.5e-35 119.4 0.5 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Involucrin PF00904.12 GAP84864.1 - 9.4 7.1 5.9 0.53 10.9 0.4 1.8 2 0 0 2 2 2 0 Involucrin repeat Pyr_redox_3 PF13738.1 GAP84865.1 - 0.0014 18.7 0.0 0.0023 18.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UbiD PF01977.11 GAP84865.1 - 0.14 10.5 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase DUF1275 PF06912.6 GAP84867.1 - 3.8e-42 143.8 8.6 4.9e-42 143.4 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) PEP_mutase PF13714.1 GAP84868.1 - 2e-33 115.6 0.2 1.9e-23 82.9 0.1 2.1 1 1 1 2 2 2 2 Phosphoenolpyruvate phosphomutase ICL PF00463.16 GAP84868.1 - 2.3e-11 42.6 0.3 3.4e-11 42.0 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family BSP_II PF05432.6 GAP84869.1 - 0.021 14.1 3.0 0.92 8.7 0.2 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) FAM176 PF14851.1 GAP84869.1 - 0.18 11.5 0.8 0.45 10.1 0.1 1.8 2 0 0 2 2 2 0 FAM176 family Mak16 PF04874.9 GAP84869.1 - 0.67 10.0 7.0 1.1 9.4 0.7 2.1 2 0 0 2 2 2 0 Mak16 protein C-terminal region Prothymosin PF03247.9 GAP84869.1 - 0.91 9.7 12.4 1.7 8.8 1.0 2.1 2 0 0 2 2 2 0 Prothymosin/parathymosin family Myc_N PF01056.13 GAP84869.1 - 1.9 7.5 3.5 3.3 6.8 0.1 2.0 2 0 0 2 2 2 0 Myc amino-terminal region Nucleoplasmin PF03066.10 GAP84869.1 - 6.6 6.2 6.4 1.9 8.0 0.4 2.1 2 0 0 2 2 2 0 Nucleoplasmin AATase PF07247.7 GAP84870.1 - 0.00051 18.7 0.0 0.00054 18.6 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 GAP84870.1 - 0.013 14.3 0.2 0.019 13.8 0.1 1.1 1 0 0 1 1 1 0 Condensation domain PLAC8 PF04749.12 GAP84871.1 - 1.6e-26 92.9 16.9 2.2e-26 92.4 11.7 1.2 1 0 0 1 1 1 1 PLAC8 family DSBA PF01323.15 GAP84874.1 - 6.9e-26 90.9 0.0 8.8e-26 90.6 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Cupin_1 PF00190.17 GAP84874.1 - 0.033 13.6 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Cupin GST_N PF02798.15 GAP84875.1 - 1.4e-14 53.9 0.0 2.5e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAP84875.1 - 1.4e-10 41.0 0.0 2.2e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAP84875.1 - 3.7e-09 36.3 0.0 6.1e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAP84875.1 - 2.7e-08 33.7 0.0 5.8e-08 32.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAP84875.1 - 3.9e-08 33.6 0.1 5.7e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAP84875.1 - 4.3e-08 33.2 0.0 7.8e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain 2-Hacid_dh_C PF02826.14 GAP84876.1 - 1.5e-40 138.2 0.0 1.6e-39 134.9 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAP84876.1 - 1.6e-22 79.3 0.0 2.1e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.16 GAP84876.1 - 0.023 14.2 0.9 3.9 7.0 0.0 3.0 2 1 1 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.7 GAP84876.1 - 0.027 13.8 0.0 0.56 9.5 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 GAP84876.1 - 0.04 13.7 0.1 0.21 11.4 0.0 2.1 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 GAP84876.1 - 0.59 10.6 2.8 11 6.5 1.0 2.7 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Kelch_5 PF13854.1 GAP84877.1 - 0.00011 22.0 1.1 0.11 12.4 0.1 3.3 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 GAP84877.1 - 0.00069 19.7 6.5 0.37 11.0 0.4 4.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 GAP84877.1 - 0.0014 18.7 4.0 1 9.6 0.0 3.8 3 0 0 3 3 3 2 Kelch motif SKG6 PF08693.5 GAP84877.1 - 0.94 8.8 4.0 0.48 9.7 0.5 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Kelch_4 PF13418.1 GAP84877.1 - 1.8 8.3 9.3 7.7 6.3 0.5 4.0 4 0 0 4 4 4 0 Galactose oxidase, central domain CUE PF02845.11 GAP84879.1 - 2.4e-06 26.8 0.0 4.1e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 CUE domain DUF3697 PF12478.3 GAP84879.1 - 0.012 15.2 0.0 0.034 13.7 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-associated protein 2 p450 PF00067.17 GAP84880.1 - 6.6e-66 222.7 0.0 7.9e-66 222.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_1 PF00175.16 GAP84881.1 - 1.8e-28 99.2 0.0 3.9e-28 98.1 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 GAP84881.1 - 1.9e-26 91.6 0.2 3e-26 91.0 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.19 GAP84881.1 - 3e-26 91.4 0.0 6e-26 90.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 GAP84881.1 - 2.2e-05 24.4 0.0 0.00044 20.1 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 GAP84881.1 - 0.004 17.0 0.0 0.01 15.7 0.0 1.7 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DUF3328 PF11807.3 GAP84883.1 - 2.3e-42 145.1 0.2 2.9e-42 144.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Cauli_VI PF01693.11 GAP84884.1 - 3.1e-08 33.5 1.0 5.1e-08 32.8 0.7 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin Pkinase PF00069.20 GAP84886.1 - 8.3e-63 211.9 0.0 1.4e-62 211.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP84886.1 - 1.7e-36 125.6 0.0 3.2e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 GAP84886.1 - 8.8e-27 92.6 14.5 7.9e-17 60.7 2.4 2.4 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 GAP84886.1 - 1.7e-18 66.0 31.5 4.9e-11 42.1 7.5 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 GAP84886.1 - 2.9e-14 53.3 2.5 1e-13 51.5 1.8 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 GAP84886.1 - 0.022 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like FYVE_2 PF02318.11 GAP84886.1 - 0.7 9.7 13.8 1.2 9.0 2.2 2.7 2 0 0 2 2 2 0 FYVE-type zinc finger DUF4206 PF13901.1 GAP84886.1 - 9.1 5.7 19.0 3.2 7.2 5.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4206) She9_MDM33 PF05546.6 GAP84887.1 - 3.7e-80 268.3 4.0 5.5e-80 267.8 2.7 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family PsbH PF00737.15 GAP84887.1 - 0.11 12.1 0.6 0.19 11.3 0.4 1.3 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein Cep57_CLD_2 PF14197.1 GAP84887.1 - 0.3 11.0 4.5 0.41 10.6 0.0 2.8 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Pox_A_type_inc PF04508.7 GAP84887.1 - 0.54 10.1 2.6 2.6 8.0 0.0 3.0 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Uds1 PF15456.1 GAP84887.1 - 2.6 8.0 9.5 0.18 11.7 2.3 2.3 2 1 0 2 2 2 0 Up-regulated During Septation eIF-1a PF01176.14 GAP84888.1 - 2.1e-16 59.0 0.0 4e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DUF2554 PF10829.3 GAP84888.1 - 0.086 12.9 0.1 0.77 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2554) ALG3 PF05208.8 GAP84889.1 - 8.1e-87 291.8 11.4 9.6e-87 291.5 7.9 1.0 1 0 0 1 1 1 1 ALG3 protein DUF4408 PF14364.1 GAP84889.1 - 5.3 6.6 8.1 0.2 11.2 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4408) DAO PF01266.19 GAP84890.1 - 3.8e-29 101.7 2.1 5e-29 101.3 1.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAP84890.1 - 5.2e-06 26.3 0.1 2.4e-05 24.2 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAP84890.1 - 3.7e-05 22.9 0.5 0.00015 20.9 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 GAP84890.1 - 0.0022 16.9 0.2 0.0047 15.8 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 GAP84890.1 - 0.0031 17.8 0.1 0.0097 16.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAP84890.1 - 0.041 13.7 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP84890.1 - 0.053 13.5 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAP84890.1 - 0.055 11.9 0.0 0.083 11.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein FYVE_2 PF02318.11 GAP84891.1 - 0.15 12.0 22.2 0.49 10.3 1.3 3.3 3 0 0 3 3 3 0 FYVE-type zinc finger Sar8_2 PF03058.9 GAP84891.1 - 2.3 8.6 16.4 0.64 10.3 0.2 3.4 3 0 0 3 3 3 0 Sar8.2 family Clr2 PF10383.4 GAP84892.1 - 3.7e-10 39.9 0.0 8.2e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 Med3 PF11593.3 GAP84892.1 - 0.0034 16.6 0.9 0.0043 16.3 0.6 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal TP2 PF01254.13 GAP84892.1 - 0.017 15.4 9.3 0.034 14.5 6.5 1.4 1 0 0 1 1 1 0 Nuclear transition protein 2 adh_short PF00106.20 GAP84893.1 - 7.8e-13 48.6 3.9 8.2e-13 48.6 0.6 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAP84893.1 - 2.5e-06 27.2 0.2 3.7e-06 26.7 0.2 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 GAP84893.1 - 0.059 13.4 0.2 0.097 12.7 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Clat_adaptor_s PF01217.15 GAP84894.1 - 1.2e-56 190.4 2.0 1.3e-56 190.2 1.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain eIF3g PF12353.3 GAP84895.1 - 0.005 16.7 5.3 0.66 9.8 0.9 2.7 2 0 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_2 PF13696.1 GAP84895.1 - 0.2 11.1 20.3 1.8 8.1 6.2 2.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.1 GAP84895.1 - 1.8 8.3 9.5 0.091 12.5 1.4 2.5 2 0 0 2 2 2 0 Zinc knuckle Ist1 PF03398.9 GAP84896.1 - 1.9e-63 212.7 1.0 2.4e-63 212.4 0.7 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF2422 PF10337.4 GAP84897.1 - 1.1e-20 73.8 3.8 6.3e-13 48.3 0.1 3.3 2 2 2 4 4 4 2 Protein of unknown function (DUF2422) ALMT PF11744.3 GAP84897.1 - 2.5e-15 56.0 12.4 6.3e-14 51.4 4.2 2.7 2 1 0 2 2 2 2 Aluminium activated malate transporter FUSC_2 PF13515.1 GAP84897.1 - 2.2e-13 50.2 14.2 2.2e-13 50.2 9.9 2.7 2 0 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 GAP84897.1 - 4.4e-06 25.4 18.4 2.5e-05 22.9 10.1 2.5 2 0 0 2 2 2 2 Fusaric acid resistance protein family DUF2421 PF10334.4 GAP84897.1 - 0.00092 18.8 0.1 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) adh_short PF00106.20 GAP84898.1 - 1.3e-24 86.9 0.0 1.7e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP84898.1 - 1.5e-17 64.2 0.0 1.8e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP84898.1 - 1.9e-08 34.1 0.0 2.6e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 GAP84898.1 - 0.0025 17.5 0.0 0.0053 16.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 GAP84898.1 - 0.0038 16.7 0.1 0.0051 16.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glucodextran_N PF09137.6 GAP84899.1 - 0.092 11.9 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Glucodextranase, domain N AWPM-19 PF05512.6 GAP84900.1 - 2.5 8.1 9.3 0.18 11.7 1.0 2.4 2 0 0 2 2 2 0 AWPM-19-like family P19Arf_N PF07392.7 GAP84900.1 - 2.9 8.1 6.3 1.2 9.3 0.9 2.9 3 0 0 3 3 3 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus AA_permease_2 PF13520.1 GAP84901.1 - 0.0044 15.6 0.2 0.0052 15.3 0.1 1.0 1 0 0 1 1 1 1 Amino acid permease MARVEL PF01284.18 GAP84901.1 - 0.023 14.5 0.7 0.026 14.3 0.5 1.1 1 0 0 1 1 1 0 Membrane-associating domain DUF4064 PF13273.1 GAP84901.1 - 0.041 13.9 1.7 0.16 12.0 1.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) COX1 PF00115.15 GAP84901.1 - 0.047 12.3 0.4 0.057 12.0 0.3 1.2 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I Yip1 PF04893.12 GAP84901.1 - 0.065 12.7 0.6 0.073 12.5 0.4 1.1 1 0 0 1 1 1 0 Yip1 domain DUF3810 PF12725.2 GAP84901.1 - 0.12 11.2 0.3 0.15 10.9 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Sod_Cu PF00080.15 GAP84902.1 - 1.7e-12 47.7 0.0 2.2e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Aminotran_5 PF00266.14 GAP84904.1 - 2.3e-20 72.6 0.0 2.4e-19 69.3 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V Zn_clus PF00172.13 GAP84905.1 - 3.1e-06 27.0 7.8 4.3e-06 26.5 5.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF202 PF02656.10 GAP84906.1 - 0.037 14.2 4.1 0.037 14.2 2.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF202) zf-C2H2 PF00096.21 GAP84907.1 - 6.7e-06 26.1 21.8 0.00079 19.6 0.3 4.6 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP84907.1 - 0.026 14.8 0.3 0.026 14.8 0.2 4.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 GAP84907.1 - 0.027 14.3 0.8 0.11 12.4 0.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 GAP84907.1 - 0.54 10.3 5.6 0.71 10.0 2.7 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) TRP PF06011.7 GAP84908.1 - 1e-121 406.5 16.7 1.3e-121 406.2 11.6 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 GAP84908.1 - 1.3e-38 132.1 2.3 1.9e-38 131.6 1.6 1.3 1 0 0 1 1 1 1 ML-like domain Proteasome PF00227.21 GAP84909.1 - 3.2e-48 163.5 0.1 3.8e-48 163.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF3222 PF11519.3 GAP84909.1 - 0.015 15.2 0.7 5.2 7.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3222) DUF554 PF04474.7 GAP84909.1 - 0.045 12.9 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF554) Peptidase_M22 PF00814.20 GAP84910.1 - 3.8e-44 151.2 0.4 6.6e-15 55.3 0.1 4.0 4 0 0 4 4 4 4 Glycoprotease family Tubulin PF00091.20 GAP84911.1 - 1.2e-54 185.4 0.0 1.7e-54 184.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 GAP84911.1 - 4.5e-43 146.2 0.0 7e-43 145.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 GAP84911.1 - 0.00054 19.4 0.0 0.00091 18.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Peptidase_S8 PF00082.17 GAP84912.1 - 1.9e-42 145.3 8.1 2.5e-42 144.9 5.6 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 GAP84912.1 - 3.1e-06 27.6 0.1 8e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 Peptidase inhibitor I9 DUF1989 PF09347.5 GAP84913.1 - 2.6e-49 166.8 0.0 3.5e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) DNA_pol_alpha_N PF12254.3 GAP84913.1 - 0.14 11.9 0.1 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal Terpene_synth_C PF03936.11 GAP84914.1 - 3.5e-13 49.4 0.1 4.7e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Med16 PF11635.3 GAP84915.1 - 3.1e-103 346.2 0.2 4e-103 345.8 0.1 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 SIR2 PF02146.12 GAP84916.1 - 4.1e-28 98.3 0.0 1.9e-27 96.1 0.0 1.9 1 1 0 1 1 1 1 Sir2 family SNF2_N PF00176.18 GAP84917.1 - 3.1e-66 223.2 0.1 5.3e-66 222.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 GAP84917.1 - 1.6e-24 85.2 2.1 5.6e-15 54.7 0.2 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 GAP84917.1 - 9e-14 51.1 0.0 2.6e-13 49.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FF PF01846.14 GAP84918.1 - 1.5e-48 162.5 13.8 1.9e-13 50.1 0.1 7.4 7 1 0 7 7 7 6 FF domain WW PF00397.21 GAP84918.1 - 2.5e-18 65.5 13.6 1.4e-09 37.6 1.9 2.7 2 0 0 2 2 2 2 WW domain Trs65 PF12735.2 GAP84919.1 - 1.9e-67 227.7 0.0 3.6e-67 226.8 0.0 1.4 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 DUF2710 PF10921.3 GAP84919.1 - 0.12 12.5 0.3 0.33 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2710) Guanylate_cyc PF00211.15 GAP84920.1 - 0.019 14.3 0.1 0.033 13.5 0.1 1.4 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain Filament PF00038.16 GAP84923.1 - 0.0017 17.9 10.4 0.0017 17.9 7.2 6.5 4 2 1 6 6 6 4 Intermediate filament protein Tox-URI2 PF15653.1 GAP84923.1 - 1.6 8.9 6.6 6 7.1 0.1 3.3 2 0 0 2 2 2 0 URI fold toxin 2 MtrG PF04210.8 GAP84923.1 - 3 7.5 4.7 9.3 6.0 0.0 3.6 4 0 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G Reo_sigmaC PF04582.7 GAP84923.1 - 8.3 5.4 33.5 0.65 9.1 4.6 4.1 4 0 0 4 4 4 0 Reovirus sigma C capsid protein Glyco_hydro_88 PF07470.8 GAP84924.1 - 8e-39 133.6 1.2 9.2e-39 133.4 0.8 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 NAD_binding_4 PF07993.7 GAP84926.1 - 5.7e-37 126.9 0.0 8.7e-37 126.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 GAP84926.1 - 5.9e-30 103.9 0.1 1.5e-29 102.6 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 GAP84926.1 - 5.5e-10 39.3 0.0 2.3e-09 37.3 0.0 2.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 GAP84926.1 - 1.8e-05 24.3 0.0 0.00016 21.1 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAP84926.1 - 0.00045 20.1 0.5 0.0028 17.5 0.4 2.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP84926.1 - 0.022 14.4 0.2 0.12 11.9 0.1 2.2 1 1 0 1 1 1 0 KR domain Methyltransf_2 PF00891.13 GAP84927.1 - 3.4e-36 124.6 0.0 4.4e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 GAP84927.1 - 0.00014 22.3 0.0 0.00032 21.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP84927.1 - 0.0012 19.3 0.0 0.0024 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAP84927.1 - 0.0018 17.6 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 GAP84927.1 - 0.007 16.7 0.0 0.025 14.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP84927.1 - 0.014 15.0 0.0 0.045 13.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 GAP84927.1 - 0.014 15.1 0.0 0.043 13.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Lyase_aromatic PF00221.14 GAP84928.1 - 5.3e-159 529.6 4.9 7.3e-159 529.1 3.4 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase FAD_binding_3 PF01494.14 GAP84929.1 - 3.4e-47 161.2 0.0 4.6e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAP84929.1 - 3.9e-09 35.8 0.2 1.9e-06 27.0 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAP84929.1 - 2.3e-05 24.3 0.2 5.2e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAP84929.1 - 9.1e-05 21.4 0.0 0.0035 16.2 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 GAP84929.1 - 9.4e-05 22.3 0.0 0.0002 21.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAP84929.1 - 0.00014 20.4 0.1 0.00025 19.6 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 GAP84929.1 - 0.00044 19.4 0.0 0.00074 18.6 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 GAP84929.1 - 0.001 19.1 0.0 0.026 14.5 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 GAP84929.1 - 0.0022 17.4 0.1 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 GAP84929.1 - 0.0049 17.2 0.1 0.03 14.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAP84929.1 - 0.0058 15.7 0.0 0.02 13.9 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 GAP84929.1 - 0.022 14.9 0.0 0.056 13.7 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 GAP84929.1 - 0.062 12.2 0.1 0.14 11.0 0.1 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 GAP84929.1 - 0.14 11.5 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_23 PF13489.1 GAP84930.1 - 1.4e-11 44.3 0.0 3.1e-11 43.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP84930.1 - 8.3e-07 29.5 0.0 5.4e-05 23.7 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP84930.1 - 2.7e-05 24.5 0.0 7.9e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP84930.1 - 0.00075 19.9 0.0 0.0023 18.3 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP84930.1 - 0.00079 19.0 0.0 0.004 16.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP84930.1 - 0.0099 15.0 0.0 0.044 12.8 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 GAP84930.1 - 0.044 13.1 0.0 0.087 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain p450 PF00067.17 GAP84932.1 - 3.2e-74 250.1 0.0 3.6e-74 249.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3445 PF11927.3 GAP84934.1 - 4.6e-76 255.4 0.0 5.7e-76 255.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF846 PF05832.7 GAP84935.1 - 4.9e-42 142.9 4.1 5.9e-42 142.7 2.8 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Dpy19 PF10034.4 GAP84935.1 - 0.096 10.8 0.0 0.081 11.0 0.0 1.1 1 0 0 1 1 1 0 Q-cell neuroblast polarisation DUF4191 PF13829.1 GAP84935.1 - 0.7 8.9 2.4 0.76 8.8 0.7 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) Podoplanin PF05808.6 GAP84936.1 - 0.0011 18.5 2.0 0.0011 18.5 1.4 2.2 2 0 0 2 2 2 1 Podoplanin DUF4448 PF14610.1 GAP84936.1 - 0.025 14.0 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) P12 PF12669.2 GAP84936.1 - 0.042 14.0 0.1 0.042 14.0 0.1 2.1 2 0 0 2 2 2 0 Virus attachment protein p12 family SelP_N PF04592.9 GAP84936.1 - 2.6 7.3 7.3 5 6.4 5.0 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MGC-24 PF05283.6 GAP84936.1 - 6.6 6.4 16.8 0.097 12.4 3.9 2.2 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) DUF726 PF05277.7 GAP84937.1 - 3.4e-125 417.4 0.7 4.8e-125 417.0 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Lipase_3 PF01764.20 GAP84937.1 - 0.045 13.3 0.0 0.097 12.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) p450 PF00067.17 GAP84938.1 - 2e-68 231.0 0.0 2.6e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fcf1 PF04900.7 GAP84939.1 - 2.5e-17 62.8 0.0 6.3e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 Fcf1 CDC45 PF02724.9 GAP84939.1 - 2.7 5.9 7.8 3.6 5.4 5.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SpoIIE PF07228.7 GAP84940.1 - 2.6e-06 27.2 0.0 2.2e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 GAP84940.1 - 3.9e-05 23.1 0.0 5.1e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 GAP84940.1 - 0.00081 18.8 0.1 0.42 9.9 0.0 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C PH PF00169.24 GAP84941.1 - 0.00017 21.7 0.0 0.00066 19.8 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 GAP84941.1 - 0.00071 19.7 0.0 0.0044 17.1 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Lipase_GDSL_2 PF13472.1 GAP84942.1 - 4.8e-20 72.4 0.0 6.9e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAP84942.1 - 3.6e-08 33.5 0.0 4.2e-06 26.7 0.0 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF3854 PF12965.2 GAP84942.1 - 0.064 12.9 0.0 0.34 10.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3854) PCI PF01399.22 GAP84943.1 - 2.1e-09 37.6 0.0 1.3e-08 35.0 0.0 2.3 2 1 0 2 2 2 1 PCI domain RPN7 PF10602.4 GAP84943.1 - 0.042 13.2 0.1 0.076 12.3 0.1 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Ins_allergen_rp PF06757.8 GAP84943.1 - 0.055 12.9 0.3 0.12 11.8 0.2 1.6 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification HSCB_C PF07743.8 GAP84944.1 - 3.5e-15 56.2 0.1 7.9e-15 55.0 0.1 1.6 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 GAP84944.1 - 4.5e-07 29.5 0.0 8.6e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain F-box-like PF12937.2 GAP84945.1 - 0.028 14.1 0.1 0.095 12.4 0.1 2.0 1 1 0 1 1 1 0 F-box-like SNF2_N PF00176.18 GAP84946.1 - 2.3e-32 112.0 0.0 1.7e-29 102.5 0.0 2.1 2 0 0 2 2 2 2 SNF2 family N-terminal domain DEAD PF00270.24 GAP84946.1 - 0.00053 19.5 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP84946.1 - 0.012 15.4 0.1 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Aldo_ket_red PF00248.16 GAP84948.1 - 6.5e-54 182.6 0.0 7.4e-54 182.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Dus PF01207.12 GAP84949.1 - 2.9e-24 85.4 0.0 1.7e-20 73.1 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) Pkinase PF00069.20 GAP84950.1 - 3.9e-66 222.8 0.0 4.8e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP84950.1 - 1.3e-31 109.6 0.0 1.8e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 GAP84950.1 - 0.00053 20.4 0.4 0.0017 18.8 0.3 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 GAP84950.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.4 1 1 0 1 1 1 0 Kinase-like APH PF01636.18 GAP84950.1 - 0.12 12.0 0.2 3 7.5 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DOMON PF03351.12 GAP84951.1 - 2.1e-07 30.8 0.1 5.4e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 DOMON domain UPF0121 PF03661.8 GAP84951.1 - 0.034 13.3 0.5 0.055 12.6 0.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0121) DUF2427 PF10348.4 GAP84951.1 - 0.17 11.4 10.3 0.032 13.7 3.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) Serglycin PF04360.7 GAP84951.1 - 3.2 7.4 18.2 11 5.6 12.6 1.9 1 1 0 1 1 1 0 Serglycin Tetraspannin PF00335.15 GAP84951.1 - 4.9 6.3 10.7 14 4.8 7.4 1.8 1 1 0 1 1 1 0 Tetraspanin family RAP1 PF07218.6 GAP84951.1 - 5 5.0 9.8 6.8 4.6 6.8 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) WD40 PF00400.27 GAP84952.1 - 6e-46 152.7 16.3 3e-09 36.4 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat PRP4 PF08799.6 GAP84952.1 - 5.7e-15 54.2 4.1 1.1e-14 53.3 2.8 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like eIF2A PF08662.6 GAP84952.1 - 0.0052 16.5 0.0 0.057 13.1 0.0 2.7 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 GAP84952.1 - 0.0091 15.1 0.0 0.39 9.7 0.0 2.4 2 0 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal DUF4165 PF13752.1 GAP84952.1 - 0.22 11.3 0.2 0.97 9.2 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4165) Cyclin_N PF00134.18 GAP84953.1 - 8.9e-11 41.4 0.1 1.4e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 GAP84953.1 - 0.0098 15.8 0.0 4.8 7.1 0.0 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain TFIIB PF00382.14 GAP84953.1 - 0.055 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat ATP_sub_h PF10775.4 GAP84954.1 - 2.2e-25 88.1 1.2 3.3e-25 87.5 0.8 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 GAP84954.1 - 0.015 15.2 0.2 0.022 14.6 0.1 1.4 1 1 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 Pkinase PF00069.20 GAP84955.1 - 2.9e-71 239.6 0.0 4e-71 239.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP84955.1 - 1.9e-31 109.0 0.0 2.7e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 GAP84955.1 - 5.6e-13 49.1 0.8 5.6e-13 49.1 0.5 3.0 3 0 0 3 3 3 1 Protein kinase C terminal domain Kinase-like PF14531.1 GAP84955.1 - 3.2e-10 39.4 0.1 8.3e-10 38.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 GAP84955.1 - 5.5e-05 22.9 0.0 0.00022 20.9 0.0 2.1 1 1 0 1 1 1 1 C2 domain Kdo PF06293.9 GAP84955.1 - 0.019 14.0 0.1 0.032 13.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 GAP84955.1 - 0.061 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 GAP84955.1 - 0.075 12.5 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase GFA PF04828.9 GAP84957.1 - 4.3e-17 61.8 0.2 5.4e-17 61.5 0.1 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 GAP84957.1 - 0.0068 15.8 1.7 0.0068 15.8 1.2 2.5 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.1 GAP84957.1 - 4.5 7.0 9.8 0.64 9.7 0.2 2.4 2 0 0 2 2 2 0 Nudix N-terminal Creatininase PF02633.9 GAP84958.1 - 0.23 10.5 1.4 0.43 9.6 1.0 1.4 1 0 0 1 1 1 0 Creatinine amidohydrolase Matrilin_ccoil PF10393.4 GAP84959.1 - 0.0062 15.8 0.2 0.018 14.4 0.2 1.8 1 0 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin DUF1993 PF09351.5 GAP84959.1 - 0.028 14.3 0.2 0.028 14.3 0.1 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF1993) DUF2458 PF10454.4 GAP84959.1 - 0.27 11.1 9.2 0.76 9.6 6.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) CorA PF01544.13 GAP84959.1 - 1.2 8.0 4.6 0.41 9.6 0.6 2.1 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein CDC37_N PF03234.9 GAP84959.1 - 1.5 9.0 9.4 0.72 10.1 4.5 2.0 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Syntaxin-6_N PF09177.6 GAP84959.1 - 2.6 8.4 10.6 0.31 11.4 1.7 2.9 3 1 1 4 4 4 0 Syntaxin 6, N-terminal SUZ PF12752.2 GAP84960.1 - 3e-05 24.4 0.2 3e-05 24.4 0.1 3.3 2 1 1 3 3 3 1 SUZ domain DUF3945 PF13101.1 GAP84960.1 - 0.033 13.4 0.5 0.055 12.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3945) TMEM247 PF15444.1 GAP84960.1 - 0.06 13.1 0.2 0.071 12.9 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 247 Fe_hyd_lg_C PF02906.9 GAP84961.1 - 4.4e-62 209.9 0.0 7.8e-62 209.1 0.0 1.4 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain SH3_9 PF14604.1 GAP84963.1 - 7.3e-32 108.7 2.5 4.9e-15 54.8 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 GAP84963.1 - 2.2e-26 90.9 3.3 9.4e-13 47.3 0.3 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 GAP84963.1 - 6e-16 57.6 0.0 5.6e-08 32.1 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 GAP84963.1 - 3.7e-08 33.3 0.0 7.1e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Glutaredoxin PF00462.19 GAP84964.1 - 3.2e-16 59.0 0.0 2.5e-15 56.1 0.0 2.4 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 GAP84964.1 - 5.1e-14 51.8 0.0 1.1e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 GAP84964.1 - 0.0036 17.3 0.0 0.22 11.6 0.0 2.4 1 1 1 2 2 2 1 Thioredoxin-like HyaE PF07449.6 GAP84964.1 - 0.0049 16.7 0.0 0.027 14.3 0.0 2.2 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 GAP84964.1 - 0.013 15.2 0.1 0.063 13.1 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin domain TrbC_Ftype PF09673.5 GAP84964.1 - 0.069 12.7 0.2 0.37 10.4 0.0 2.3 2 1 1 3 3 3 0 Type-F conjugative transfer system pilin assembly protein AAA_29 PF13555.1 GAP84965.1 - 0.099 12.1 0.7 0.19 11.3 0.4 1.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Ion_trans PF00520.26 GAP84966.1 - 1.4e-104 347.6 90.8 2.2e-33 115.2 8.2 5.2 5 0 0 5 5 5 5 Ion transport protein JSRP PF15312.1 GAP84966.1 - 0.13 12.2 0.1 0.5 10.3 0.0 2.1 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein EamA PF00892.15 GAP84967.1 - 0.00028 20.9 3.1 0.00028 20.9 2.2 1.6 2 0 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 GAP84967.1 - 0.016 15.4 5.7 0.027 14.6 3.8 1.5 1 1 0 1 1 1 0 Multidrug resistance efflux transporter UPF0546 PF10639.4 GAP84967.1 - 0.056 13.2 1.3 0.088 12.6 0.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0546 DUF2754 PF10953.3 GAP84967.1 - 0.25 11.4 2.1 2.7 8.1 0.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2754) TFIIA_gamma_N PF02268.11 GAP84968.1 - 1.4e-25 88.5 0.2 2.1e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 GAP84968.1 - 1.8e-23 82.0 1.4 2.5e-23 81.6 1.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Epimerase_Csub PF13950.1 GAP84968.1 - 0.047 13.6 0.2 0.14 12.1 0.0 1.9 2 1 0 2 2 2 0 UDP-glucose 4-epimerase C-term subunit DSBA PF01323.15 GAP84969.1 - 7.3e-37 126.7 0.0 8.2e-37 126.6 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.1 GAP84969.1 - 0.0022 17.7 0.1 0.56 10.0 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_4 PF13462.1 GAP84969.1 - 0.0082 16.1 0.1 0.031 14.2 0.0 1.8 2 1 0 2 2 2 1 Thioredoxin GRAS PF03514.9 GAP84969.1 - 0.056 12.1 0.0 0.074 11.7 0.0 1.1 1 0 0 1 1 1 0 GRAS domain family Asp PF00026.18 GAP84970.1 - 4.6e-08 32.6 0.0 3.2e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic aspartyl protease HAD PF12710.2 GAP84971.1 - 1.5e-05 25.2 0.0 2.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Shisa PF13908.1 GAP84972.1 - 0.019 15.1 0.0 0.052 13.7 0.0 1.8 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Sulfotransfer_3 PF13469.1 GAP84973.1 - 0.023 15.6 0.3 0.04 14.8 0.2 1.5 1 1 0 1 1 1 0 Sulfotransferase family DUF4367 PF14285.1 GAP84974.1 - 0.047 13.0 0.1 0.084 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) GMC_oxred_N PF00732.14 GAP84975.1 - 1.3e-63 214.9 0.0 1.9e-63 214.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAP84975.1 - 2.2e-30 105.8 0.0 3.9e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 GAP84975.1 - 0.00022 20.2 0.2 0.00033 19.7 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAP84975.1 - 0.014 14.2 0.2 3.2 6.5 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.19 GAP84975.1 - 0.044 12.6 0.2 0.5 9.2 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 GAP84975.1 - 0.23 10.5 1.0 0.53 9.3 0.1 2.1 3 0 0 3 3 3 0 Thi4 family NAD_binding_8 PF13450.1 GAP84975.1 - 0.29 11.1 1.4 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain MFS_1 PF07690.11 GAP84976.1 - 2.5e-23 82.3 43.3 2.5e-23 82.3 30.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Exo70 PF03081.10 GAP84976.1 - 0.25 10.0 0.0 0.34 9.6 0.0 1.1 1 0 0 1 1 1 0 Exo70 exocyst complex subunit zf-Di19 PF05605.7 GAP84977.1 - 0.0087 16.1 2.3 0.0087 16.1 1.6 3.0 4 0 0 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 GAP84977.1 - 0.025 14.9 14.6 0.027 14.7 1.8 4.6 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 GAP84977.1 - 0.55 10.3 7.6 1.6 8.8 1.4 2.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF629 PF04780.7 GAP84977.1 - 1.8 7.0 10.6 0.095 11.2 2.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF629) TPR_10 PF13374.1 GAP84978.1 - 2.2e-34 116.3 0.0 2.6e-11 43.0 0.0 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAP84978.1 - 5e-22 77.6 0.0 8.9e-09 35.1 0.0 3.8 1 1 2 3 3 3 3 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 GAP84978.1 - 1.3e-15 57.0 0.0 2.6e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily NB-ARC PF00931.17 GAP84978.1 - 9.4e-08 31.2 0.0 7.8e-07 28.2 0.0 2.3 1 1 0 1 1 1 1 NB-ARC domain TPR_2 PF07719.12 GAP84978.1 - 2.6e-06 26.9 0.0 0.51 10.3 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAP84978.1 - 2e-05 24.0 0.1 0.18 11.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAP84978.1 - 8.4e-05 22.1 0.0 0.027 14.1 0.0 3.1 1 1 2 3 3 3 2 TPR repeat TPR_14 PF13428.1 GAP84978.1 - 0.0003 21.1 0.2 4.1 8.3 0.0 4.1 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAP84978.1 - 0.0011 19.0 0.2 0.77 10.1 0.0 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAP84978.1 - 0.0017 17.8 0.0 2.2 8.0 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_4 PF07721.9 GAP84978.1 - 0.0045 17.2 1.7 2.1 9.0 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat NACHT PF05729.7 GAP84978.1 - 0.033 13.8 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Cpn60_TCP1 PF00118.19 GAP84979.1 - 8.3e-134 446.8 4.8 9.3e-134 446.6 3.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-H2C2 PF09337.5 GAP84980.1 - 3.3e-20 71.2 3.5 6.5e-20 70.2 2.5 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 GAP84980.1 - 0.057 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family MFS_1 PF07690.11 GAP84981.1 - 2.9e-14 52.5 19.8 2.9e-14 52.5 13.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Ribosomal_S2 PF00318.15 GAP84982.1 - 8.1e-49 165.6 0.0 2.1e-48 164.3 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein S2 CBS PF00571.23 GAP84983.1 - 7.5e-40 134.4 7.6 4.2e-11 42.4 0.0 5.3 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 GAP84983.1 - 1.6e-10 40.5 0.0 4.4e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 PB1 domain FAD_binding_3 PF01494.14 GAP84984.1 - 9.9e-33 113.6 0.0 1.5e-32 113.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAP84984.1 - 1.8e-10 40.2 1.4 0.00041 19.3 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAP84984.1 - 1.1e-08 35.4 0.0 3.6e-08 33.7 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAP84984.1 - 1.8e-08 33.3 0.5 4.9e-05 21.9 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein Amino_oxidase PF01593.19 GAP84984.1 - 1e-07 31.4 0.5 0.0036 16.4 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 GAP84984.1 - 1.6e-06 27.3 0.2 6.3e-06 25.3 0.1 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 GAP84984.1 - 1.9e-05 24.6 0.3 0.00036 20.4 0.1 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP84984.1 - 0.00011 22.0 0.3 0.00028 20.8 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAP84984.1 - 0.00018 20.4 0.7 0.00018 20.4 0.5 2.0 3 0 0 3 3 3 1 FAD binding domain Trp_halogenase PF04820.9 GAP84984.1 - 0.0002 20.1 0.9 0.37 9.3 0.0 2.9 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox PF00070.22 GAP84984.1 - 0.00029 21.2 4.0 0.067 13.6 0.3 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAP84984.1 - 0.00056 19.0 0.3 0.0029 16.7 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 GAP84984.1 - 0.0018 18.0 1.3 0.15 11.8 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.17 GAP84984.1 - 0.0031 16.4 1.0 0.043 12.6 0.2 2.2 2 1 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 GAP84984.1 - 0.0045 16.5 0.1 0.015 14.8 0.1 1.9 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.16 GAP84984.1 - 0.045 13.5 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 ThiF family ApbA PF02558.11 GAP84984.1 - 0.15 11.5 0.4 0.4 10.1 0.3 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.2 GAP84984.1 - 0.17 10.9 3.2 0.15 11.1 1.1 1.6 2 1 0 2 2 2 0 FAD dependent oxidoreductase HET PF06985.6 GAP84985.1 - 4.4e-24 85.2 0.0 9.5e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.14 GAP84986.1 - 1.5e-22 80.1 0.0 2.1e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAP84986.1 - 5.4e-08 32.1 0.2 0.00018 20.5 0.1 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAP84986.1 - 2.6e-05 24.1 0.0 5.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAP84986.1 - 3e-05 23.0 0.6 0.00014 20.8 0.2 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 GAP84986.1 - 0.00011 22.5 0.0 0.0092 16.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAP84986.1 - 0.00013 21.8 0.0 0.0042 16.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAP84986.1 - 0.00053 19.0 0.0 0.0012 17.8 0.0 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 GAP84986.1 - 0.00059 19.9 0.0 0.002 18.2 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAP84986.1 - 0.0044 15.5 0.1 0.47 8.8 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein DUF2439 PF10382.4 GAP84986.1 - 0.013 15.6 0.2 0.029 14.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2439) GIDA PF01134.17 GAP84986.1 - 0.026 13.3 0.2 0.043 12.6 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A SE PF08491.5 GAP84986.1 - 0.043 12.6 0.0 3 6.6 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase Amino_oxidase PF01593.19 GAP84986.1 - 0.1 11.6 0.0 0.21 10.6 0.0 1.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_10 PF13460.1 GAP84987.1 - 1.7e-23 83.5 0.0 2e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAP84987.1 - 6.7e-05 22.2 0.0 9.7e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 GAP84987.1 - 0.00031 20.2 0.0 0.00043 19.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 GAP84987.1 - 0.027 14.4 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Mid2 PF04478.7 GAP84988.1 - 1.1e-05 24.9 0.0 2.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor AA_permease PF00324.16 GAP84989.1 - 4.7e-123 411.0 41.5 5.6e-123 410.7 28.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAP84989.1 - 2.9e-29 101.8 50.5 3.4e-29 101.6 35.0 1.1 1 0 0 1 1 1 1 Amino acid permease Fungal_trans PF04082.13 GAP84991.1 - 1.8e-12 46.6 0.0 2.7e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP84991.1 - 3.4e-10 39.6 7.9 6.3e-10 38.8 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.2 GAP84992.1 - 4.5e-19 69.2 17.5 6.5e-17 62.1 12.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP84992.1 - 1e-11 44.7 2.0 1.3e-11 44.4 1.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP84992.1 - 8.9e-10 38.5 3.0 4.6e-09 36.1 1.7 1.8 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 GAP84992.1 - 6.4e-05 22.7 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase CDC45 PF02724.9 GAP84993.1 - 0.28 9.1 1.9 0.38 8.7 1.3 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.1 GAP84993.1 - 4.1 7.7 6.9 8.9 6.6 4.8 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_ligase_A_M PF01068.16 GAP84994.1 - 1e-47 162.1 0.0 2.8e-45 154.1 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 GAP84994.1 - 7.2e-38 130.1 0.0 1.3e-37 129.3 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 GAP84994.1 - 8.3e-19 67.8 0.0 3.9e-11 43.2 0.0 3.5 4 0 0 4 4 4 2 ATP dependent DNA ligase C terminal region Aldose_epim PF01263.15 GAP84995.1 - 7.8e-58 195.9 0.0 9.9e-58 195.6 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase DUF3767 PF12597.3 GAP84997.1 - 1.3e-36 124.8 1.1 1.3e-36 124.7 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3767) DivIC PF04977.10 GAP84997.1 - 0.19 11.2 4.2 0.26 10.8 2.9 1.1 1 0 0 1 1 1 0 Septum formation initiator DUF1744 PF08490.7 GAP84998.1 - 6.6e-156 518.8 0.1 9e-156 518.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 GAP84998.1 - 2.5e-64 217.2 0.2 6.2e-64 215.9 0.1 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 GAP84998.1 - 5.6e-24 84.7 0.2 1.4e-23 83.3 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 GAP84998.1 - 1.9e-08 34.1 0.1 6.1e-08 32.4 0.1 1.8 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 GAP84998.1 - 4.7e-05 23.2 0.1 0.00019 21.2 0.0 2.1 2 0 0 2 2 2 1 RNase_H superfamily Ank_2 PF12796.2 GAP84999.1 - 3.4e-17 62.5 0.0 1.1e-08 35.3 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAP84999.1 - 1.1e-15 56.5 0.0 0.00012 21.7 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 GAP84999.1 - 2.5e-14 53.3 0.1 0.00027 21.3 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP84999.1 - 4.3e-13 49.0 0.0 2.8e-05 24.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP84999.1 - 1.6e-09 37.0 0.0 0.28 11.5 0.0 5.3 6 0 0 6 6 6 3 Ankyrin repeat vWA-TerF-like PF10138.4 GAP84999.1 - 6.5e-05 22.8 0.0 0.00015 21.6 0.0 1.6 1 1 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 GAP84999.1 - 0.02 15.0 0.0 0.13 12.3 0.0 2.4 1 1 0 1 1 1 0 von Willebrand factor type A domain FAD_binding_4 PF01565.18 GAP85000.1 - 2.4e-26 91.8 0.1 1.2e-25 89.5 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 GAP85000.1 - 3.7e-11 42.7 0.4 1e-10 41.3 0.3 1.8 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.20 GAP85001.1 - 2.1e-21 76.5 3.4 8.2e-21 74.6 2.4 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP85001.1 - 1.8e-10 40.8 0.4 2.5e-10 40.3 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAP85001.1 - 2.7e-06 27.0 0.0 3.3e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltrn_RNA_2 PF04013.7 GAP85001.1 - 0.035 13.6 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative SAM-dependent RNA methyltransferase Polysacc_synt_2 PF02719.10 GAP85001.1 - 0.049 12.5 0.3 0.064 12.1 0.2 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 GAP85001.1 - 0.067 13.1 0.2 0.26 11.2 0.1 2.0 1 1 0 1 1 1 0 NADH(P)-binding Peripla_BP_1 PF00532.16 GAP85001.1 - 0.069 12.3 0.1 0.097 11.8 0.1 1.1 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family Zn_clus PF00172.13 GAP85003.1 - 2.4e-07 30.5 10.1 4.2e-07 29.7 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BTV_NS2 PF04514.7 GAP85003.1 - 7.4 5.3 11.3 13 4.5 7.8 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Lin-8 PF03353.10 GAP85003.1 - 9.9 5.3 25.4 19 4.4 17.6 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Glyco_hydro_45 PF02015.11 GAP85004.1 - 3.2e-91 304.8 17.2 3.8e-91 304.6 11.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 ADH_N PF08240.7 GAP85005.1 - 2.3e-26 91.6 5.0 3.9e-26 90.9 3.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAP85005.1 - 1.9e-16 59.8 0.0 4.4e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 GAP85005.1 - 0.0052 15.9 0.0 0.0097 15.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 GAP85005.1 - 0.0092 15.5 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Tetraspannin PF00335.15 GAP85005.1 - 0.11 11.7 0.2 0.25 10.5 0.1 1.5 1 0 0 1 1 1 0 Tetraspanin family ThiF PF00899.16 GAP85005.1 - 0.16 11.8 0.6 0.97 9.2 0.7 2.1 2 0 0 2 2 2 0 ThiF family GPP34 PF05719.6 GAP85006.1 - 5.8e-64 215.9 0.0 7.1e-64 215.6 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) RPAP1_C PF08620.5 GAP85007.1 - 4.9e-13 48.7 0.0 1.6e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 GAP85007.1 - 5.4e-06 25.9 1.4 8.6e-06 25.2 0.9 1.3 1 0 0 1 1 1 1 RPAP1-like, N-terminal HUN PF08729.5 GAP85008.1 - 1.6e-13 50.3 1.2 3.6e-13 49.1 0.9 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Spt20 PF12090.3 GAP85008.1 - 0.48 9.7 9.6 0.14 11.4 3.6 2.1 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.8 GAP85008.1 - 1.3 8.8 37.5 2.9 7.7 26.0 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit adh_short PF00106.20 GAP85009.1 - 4e-16 59.3 2.1 3.1e-15 56.5 1.5 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP85009.1 - 1.5e-05 24.7 0.4 4.7e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.5 GAP85009.1 - 0.0022 17.1 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DEC-1_N PF04625.8 GAP85010.1 - 0.038 12.6 3.9 0.055 12.1 2.7 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region SURF6 PF04935.7 GAP85011.1 - 1.4e-50 171.5 43.7 1.4e-50 171.5 30.3 4.0 1 1 2 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 GAP85011.1 - 3.9e-17 62.0 1.1 3.9e-17 62.0 0.8 7.8 5 2 0 5 5 5 1 60S ribosome biogenesis protein Rrp14 Peptidase_S51 PF03575.12 GAP85012.1 - 6.4e-12 45.4 0.0 9.8e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 FMN_dh PF01070.13 GAP85014.1 - 3.3e-86 289.3 0.1 9e-48 162.9 0.0 2.1 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.20 GAP85014.1 - 0.012 14.5 0.1 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 GAP85014.1 - 0.034 13.2 0.1 0.082 12.0 0.0 1.7 1 1 0 1 1 1 0 Nitronate monooxygenase ThiG PF05690.9 GAP85014.1 - 0.049 12.7 0.1 2 7.4 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 GAP85014.1 - 0.053 12.4 0.0 0.08 11.8 0.0 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase Beta-lactamase PF00144.19 GAP85015.1 - 8e-50 169.7 0.1 1.2e-49 169.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 GAP85015.1 - 1.4e-12 47.2 0.0 1.2e-11 44.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3471) PilO PF04350.8 GAP85015.1 - 0.12 12.2 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 Pilus assembly protein, PilO Patatin PF01734.17 GAP85016.1 - 8.1e-26 91.2 0.0 2.1e-25 89.8 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase NB-ARC PF00931.17 GAP85016.1 - 1.9e-14 53.2 1.9 6.8e-10 38.2 0.5 2.4 1 1 1 2 2 2 2 NB-ARC domain AAA_16 PF13191.1 GAP85016.1 - 3e-06 27.3 0.2 2.5e-05 24.3 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 GAP85016.1 - 0.058 13.2 0.1 22 4.8 0.0 3.5 3 0 0 3 3 3 0 AAA domain Abhydrolase_6 PF12697.2 GAP85017.1 - 5.4e-11 42.8 0.1 9.1e-11 42.0 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP85017.1 - 0.00017 21.3 0.0 0.00024 20.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PSP PF04046.11 GAP85017.1 - 0.14 11.5 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 PSP Ank PF00023.25 GAP85018.1 - 5.1e-19 67.0 0.1 1.1e-07 31.2 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 GAP85018.1 - 3.7e-18 65.6 0.0 1.1e-08 35.2 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAP85018.1 - 5.8e-18 64.5 0.7 2.7e-08 33.8 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAP85018.1 - 7.4e-16 58.1 0.2 8.5e-07 29.3 0.0 4.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP85018.1 - 2.6e-15 55.0 0.0 1.8e-06 27.5 0.0 5.1 4 0 0 4 4 4 3 Ankyrin repeat NACHT PF05729.7 GAP85018.1 - 4.4e-11 42.7 0.0 7.8e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 GAP85018.1 - 7.4e-07 29.3 0.0 5.3e-06 26.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAP85018.1 - 1.3e-05 25.3 0.0 0.0001 22.4 0.0 2.5 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.17 GAP85018.1 - 0.0013 17.6 0.0 0.004 16.0 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain PGAP1 PF07819.8 GAP85018.1 - 0.0021 17.7 0.0 0.025 14.1 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein KAP_NTPase PF07693.9 GAP85018.1 - 0.004 16.1 0.4 0.21 10.5 0.0 2.2 1 1 1 2 2 2 1 KAP family P-loop domain Abhydrolase_6 PF12697.2 GAP85018.1 - 0.029 14.2 0.0 0.25 11.2 0.0 2.5 2 0 0 2 2 2 0 Alpha/beta hydrolase family AAA_5 PF07728.9 GAP85018.1 - 0.034 13.8 0.0 11 5.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 GAP85018.1 - 0.043 13.3 0.1 0.72 9.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA PF00004.24 GAP85018.1 - 0.047 13.8 0.0 0.18 12.0 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 GAP85018.1 - 0.05 13.5 0.1 1 9.2 0.0 2.8 2 1 1 3 3 3 0 AAA domain AAA_18 PF13238.1 GAP85018.1 - 0.054 13.7 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAP85018.1 - 0.071 13.9 0.0 0.22 12.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 GAP85018.1 - 0.083 12.2 0.1 0.29 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 GAP85018.1 - 0.089 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.13 GAP85018.1 - 0.096 12.1 0.1 0.25 10.8 0.1 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Abhydrolase_5 PF12695.2 GAP85018.1 - 0.1 12.3 0.2 0.32 10.7 0.2 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.9 GAP85018.1 - 0.1 11.8 0.0 0.72 9.0 0.0 2.1 2 0 0 2 2 2 0 Putative serine esterase (DUF676) AAA_10 PF12846.2 GAP85018.1 - 0.1 11.9 0.1 0.55 9.6 0.0 2.0 1 1 0 2 2 2 0 AAA-like domain LCAT PF02450.10 GAP85018.1 - 0.17 10.7 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF2075 PF09848.4 GAP85018.1 - 0.24 10.3 0.0 0.42 9.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SseC PF04888.7 GAP85019.1 - 0.003 16.9 2.0 0.088 12.1 1.4 2.2 1 1 0 1 1 1 1 Secretion system effector C (SseC) like family Methyltransf_2 PF00891.13 GAP85020.1 - 3.1e-09 36.3 0.0 5.9e-09 35.4 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase HTH_28 PF13518.1 GAP85020.1 - 0.042 13.8 0.1 0.31 11.0 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain Dimerisation PF08100.6 GAP85020.1 - 0.048 13.4 0.0 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 Dimerisation domain HTH_IclR PF09339.5 GAP85020.1 - 0.13 11.8 1.0 0.91 9.1 0.0 2.6 2 1 0 2 2 2 0 IclR helix-turn-helix domain MFS_1 PF07690.11 GAP85022.1 - 3.6e-10 39.0 46.6 1.3e-09 37.2 25.7 3.7 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF2970 PF11174.3 GAP85023.1 - 0.025 14.1 0.1 0.042 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) TMEM51 PF15345.1 GAP85023.1 - 0.026 14.2 0.0 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 Transmembrane protein 51 Plasmodium_HRP PF05403.6 GAP85024.1 - 0.011 15.3 0.1 0.014 15.0 0.1 1.1 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) UL2 PF08196.6 GAP85024.1 - 0.8 9.4 9.7 8.9 6.1 0.3 3.2 1 1 2 3 3 3 0 UL2 protein ABC_membrane PF00664.18 GAP85025.1 - 2.2e-35 122.4 11.5 2.8e-35 122.0 8.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 GAP85025.1 - 2.1e-32 112.2 0.0 3.7e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAP85025.1 - 1.8e-07 31.4 0.0 0.0031 17.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 GAP85025.1 - 3.8e-06 26.2 0.0 0.0014 17.9 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 GAP85025.1 - 8.8e-05 23.3 0.0 0.0002 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAP85025.1 - 0.00016 21.7 0.0 0.00097 19.1 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 GAP85025.1 - 0.00026 20.8 0.0 0.0029 17.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 GAP85025.1 - 0.0013 18.8 0.1 0.026 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 GAP85025.1 - 0.0025 17.2 0.0 0.0084 15.6 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 GAP85025.1 - 0.0031 16.6 0.0 0.0055 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 GAP85025.1 - 0.0043 16.5 0.0 0.0079 15.7 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.24 GAP85025.1 - 0.0057 16.8 0.0 0.025 14.7 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 GAP85025.1 - 0.014 15.7 0.0 0.041 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 GAP85025.1 - 0.019 14.9 0.0 0.07 13.0 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_10 PF12846.2 GAP85025.1 - 0.029 13.8 0.0 0.072 12.5 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain AAA_28 PF13521.1 GAP85025.1 - 0.038 13.9 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 GAP85025.1 - 0.041 13.7 0.3 0.33 10.8 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 GAP85025.1 - 0.047 12.7 0.0 0.19 10.7 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.1 GAP85025.1 - 0.053 13.8 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.4 GAP85025.1 - 0.058 11.9 0.1 0.47 8.9 0.0 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class MobB PF03205.9 GAP85025.1 - 0.073 12.7 0.0 0.23 11.1 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.10 GAP85025.1 - 0.11 11.1 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein IBR PF01485.16 GAP85027.1 - 4.4e-22 77.7 42.1 4.3e-11 42.5 2.4 4.5 3 1 1 4 4 4 3 IBR domain zf-C3HC4_2 PF13923.1 GAP85027.1 - 2.9e-05 23.9 6.9 2.9e-05 23.9 4.8 4.4 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAP85027.1 - 0.00025 20.6 4.4 0.00025 20.6 3.0 4.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAP85027.1 - 0.00034 20.3 6.5 0.00034 20.3 4.5 3.6 2 1 1 3 3 3 1 Ring finger domain UN_NPL4 PF11543.3 GAP85027.1 - 0.0077 16.4 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RING_5 PF14634.1 GAP85027.1 - 0.015 15.0 8.4 0.015 15.0 5.8 4.2 3 1 0 3 3 3 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 GAP85027.1 - 0.063 13.1 29.1 0.11 12.4 2.0 4.5 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 GAP85027.1 - 8.6 6.0 41.6 3.1 7.4 2.8 4.1 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain XPG_I PF00867.13 GAP85028.1 - 4.5e-25 87.5 0.0 8.4e-25 86.6 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 GAP85028.1 - 8.8e-23 80.4 0.0 1.7e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 GAP85028.1 - 0.00015 21.3 0.0 0.00026 20.5 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 GAP85028.1 - 0.016 15.4 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Peptidase_M42 PF05343.9 GAP85028.1 - 0.04 12.6 0.0 0.063 12.0 0.0 1.2 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase DUF2962 PF11176.3 GAP85029.1 - 2.9e-40 137.3 4.1 3.3e-40 137.1 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) ATP-synt_ab_C PF00306.22 GAP85029.1 - 0.011 16.2 0.6 0.022 15.2 0.4 1.6 1 1 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain HTH_32 PF13565.1 GAP85029.1 - 2.5 8.9 6.7 5.1 7.9 0.8 2.3 1 1 1 2 2 2 0 Homeodomain-like domain MAM33 PF02330.11 GAP85030.1 - 1e-31 110.3 1.5 1.3e-31 109.9 1.0 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Glyco_hydro_11 PF00457.12 GAP85031.1 - 3e-73 245.0 16.7 3.7e-73 244.7 11.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 RHIM PF12721.2 GAP85031.1 - 1.2 9.5 5.4 7.2 7.1 0.1 2.7 3 0 0 3 3 3 0 RIP homotypic interaction motif Transferase PF02458.10 GAP85032.1 - 9.3e-17 60.5 0.0 2.4e-07 29.5 0.0 2.5 2 1 0 2 2 2 2 Transferase family DUF883 PF05957.8 GAP85033.1 - 0.026 14.8 7.6 0.075 13.4 2.8 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Bot1p PF12298.3 GAP85033.1 - 0.27 11.1 3.3 0.16 11.9 0.2 1.8 1 1 1 2 2 2 0 Eukaryotic mitochondrial regulator protein Acyl_transf_3 PF01757.17 GAP85035.1 - 2.1e-22 79.4 24.7 2.6e-22 79.1 16.6 1.5 1 1 0 1 1 1 1 Acyltransferase family p450 PF00067.17 GAP85036.1 - 3.3e-43 147.8 0.0 1.4e-39 135.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Gag_p30 PF02093.11 GAP85036.1 - 0.058 12.5 0.0 0.14 11.3 0.0 1.6 1 0 0 1 1 1 0 Gag P30 core shell protein Pkinase PF00069.20 GAP85037.1 - 7e-26 90.9 0.0 1.3e-25 90.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP85037.1 - 9.7e-06 24.8 0.0 1.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 GAP85037.1 - 0.0031 16.6 0.0 0.0052 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Drc1-Sld2 PF11719.3 GAP85038.1 - 6.5e-95 318.7 25.4 7.6e-95 318.5 17.6 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein eIF-3c_N PF05470.7 GAP85038.1 - 0.61 8.1 7.6 0.99 7.4 5.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus zf-C3HC4 PF00097.20 GAP85039.1 - 1.7e-06 27.5 8.3 2.8e-06 26.8 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAP85039.1 - 2.4e-06 27.4 9.0 4e-06 26.7 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAP85039.1 - 2e-05 24.2 11.9 3.4e-05 23.5 8.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAP85039.1 - 0.017 15.2 8.5 0.055 13.5 5.9 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 GAP85039.1 - 0.017 14.7 12.3 0.028 14.1 8.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 GAP85039.1 - 0.11 12.0 8.1 0.21 11.1 5.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.15 GAP85039.1 - 7.2 6.2 15.5 3.6 7.1 7.8 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger DUF1996 PF09362.5 GAP85040.1 - 6.9e-72 241.8 3.4 1e-71 241.3 2.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Methyltransf_23 PF13489.1 GAP85041.1 - 3.7e-22 78.7 0.0 5.9e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP85041.1 - 3.9e-08 33.0 0.0 1.9e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP85041.1 - 2.1e-07 31.4 0.0 4.6e-06 27.1 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP85041.1 - 5.8e-07 29.9 0.0 4.2e-06 27.1 0.0 2.4 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP85041.1 - 3.5e-06 27.4 0.0 8.2e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAP85041.1 - 0.0024 16.9 0.0 0.004 16.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 GAP85041.1 - 0.015 15.6 0.0 0.072 13.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 GAP85041.1 - 0.022 14.8 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 GAP85041.1 - 0.047 12.8 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 GAP85041.1 - 0.065 13.2 0.0 0.21 11.5 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase GidB PF02527.10 GAP85041.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_16 PF10294.4 GAP85041.1 - 0.17 11.3 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Dabb PF07876.7 GAP85042.1 - 1.4e-24 86.3 0.0 1.6e-24 86.1 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Occludin_ELL PF07303.8 GAP85045.1 - 0.068 13.9 3.3 0.21 12.3 2.3 1.9 1 0 0 1 1 1 0 Occludin homology domain HAP1_N PF04849.8 GAP85045.1 - 0.3 9.9 8.0 0.1 11.5 3.0 1.8 1 1 1 2 2 2 0 HAP1 N-terminal conserved region zf-GRF PF06839.7 GAP85046.1 - 1.3e-07 31.4 1.5 1.3e-07 31.4 1.0 2.3 2 0 0 2 2 2 1 GRF zinc finger bZIP_1 PF00170.16 GAP85046.1 - 1.4e-06 28.1 7.6 3.3e-06 26.9 5.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAP85046.1 - 4.7e-05 23.1 9.3 0.00011 21.9 6.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Zn_clus PF00172.13 GAP85046.1 - 5.4e-05 23.0 11.3 5.4e-05 23.0 7.8 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-met PF12874.2 GAP85046.1 - 0.014 15.5 0.4 10 6.4 0.0 3.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 GAP85046.1 - 0.34 11.3 18.0 0.54 10.7 0.0 4.4 4 1 0 4 4 4 0 C2H2-type zinc finger Choline_transpo PF04515.7 GAP85047.1 - 1.9e-95 319.4 20.7 1.9e-95 319.4 14.4 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter Galanin PF01296.13 GAP85048.1 - 0.043 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Galanin F-box-like PF12937.2 GAP85049.1 - 0.00078 19.1 0.0 0.0023 17.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAP85049.1 - 0.012 15.2 0.0 0.034 13.8 0.0 1.7 1 0 0 1 1 1 0 F-box domain FSH1 PF03959.8 GAP85050.1 - 2.8e-25 89.0 0.0 3.6e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 GAP85050.1 - 0.0046 16.7 1.1 0.009 15.7 0.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2029 PF09594.5 GAP85050.1 - 0.12 11.8 2.7 0.21 11.0 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) Abhydrolase_2 PF02230.11 GAP85050.1 - 0.12 11.7 0.0 0.58 9.5 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase AAA_12 PF13087.1 GAP85051.1 - 3e-39 134.4 0.0 5.4e-39 133.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAP85051.1 - 1.1e-16 61.1 0.8 2.2e-16 60.1 0.5 1.4 1 0 0 1 1 1 1 AAA domain CFEM PF05730.6 GAP85052.1 - 6.4e-11 41.9 13.2 7.8e-11 41.6 9.2 1.1 1 0 0 1 1 1 1 CFEM domain Fungal_trans_2 PF11951.3 GAP85053.1 - 1.9e-05 23.4 0.0 3.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain 3Beta_HSD PF01073.14 GAP85054.1 - 1.1e-21 76.7 0.0 2.5e-12 46.1 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAP85054.1 - 4.3e-11 42.6 0.0 1e-10 41.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAP85054.1 - 4.1e-10 38.9 0.4 2.7e-07 29.7 0.0 2.6 2 1 1 3 3 3 2 Male sterility protein NAD_binding_10 PF13460.1 GAP85054.1 - 2.7e-08 34.0 0.3 5.3e-08 33.0 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAP85054.1 - 0.058 12.6 0.1 0.096 11.9 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.10 GAP85054.1 - 0.065 12.1 0.5 1 8.1 0.4 2.2 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein PsbQ PF05757.6 GAP85054.1 - 0.23 10.8 0.8 0.46 9.8 0.6 1.6 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) adh_short PF00106.20 GAP85054.1 - 1.7 8.5 7.9 5.3 6.9 3.7 2.7 2 1 0 2 2 2 0 short chain dehydrogenase Thioesterase PF00975.15 GAP85057.1 - 2.3e-11 44.3 0.0 4.1e-11 43.5 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 GAP85057.1 - 0.00027 20.9 0.0 0.00061 19.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP85057.1 - 0.0023 17.7 0.0 0.0027 17.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3638 PF12340.3 GAP85058.1 - 3.4e-96 320.6 0.1 8.1e-96 319.4 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 GAP85058.1 - 1.1e-15 56.4 0.6 2.1e-15 55.5 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) NAD_binding_9 PF13454.1 GAP85059.1 - 0.085 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Adaptin_N PF01602.15 GAP85060.1 - 1.7e-147 491.9 2.5 2.4e-147 491.4 1.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 GAP85060.1 - 1e-26 93.8 0.7 6.6e-26 91.2 0.0 2.5 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 GAP85060.1 - 1.6e-17 63.5 1.1 2.2e-07 31.0 0.0 5.0 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.17 GAP85060.1 - 3.5e-11 42.1 5.0 0.0087 16.0 0.0 6.0 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 GAP85060.1 - 8.2e-06 26.1 0.7 1.9 9.0 0.0 5.9 6 1 1 7 7 7 1 HEAT-like repeat UNC45-central PF11701.3 GAP85060.1 - 0.0013 18.4 0.2 0.19 11.3 0.1 2.7 2 2 0 2 2 2 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.3 GAP85060.1 - 0.015 14.6 0.2 1.9 7.7 0.0 3.3 2 1 1 3 3 3 0 CLASP N terminal Arm PF00514.18 GAP85060.1 - 0.018 14.8 1.3 11 5.9 0.0 5.0 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat AF0941-like PF14591.1 GAP85060.1 - 0.18 11.8 2.0 0.94 9.5 1.3 2.3 2 0 0 2 2 2 0 AF0941-like NIF3 PF01784.13 GAP85061.1 - 7.9e-59 199.1 0.0 9.9e-59 198.8 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Vps51 PF08700.6 GAP85062.1 - 5.5e-28 96.6 0.2 9.3e-28 95.9 0.2 1.4 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.7 GAP85062.1 - 0.00014 20.4 0.5 0.00018 20.1 0.3 1.1 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.4 GAP85062.1 - 0.0003 20.7 0.3 0.00048 20.0 0.2 1.3 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Sec5 PF15469.1 GAP85062.1 - 0.018 14.7 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec5 Stimulus_sens_1 PF13756.1 GAP85062.1 - 0.035 14.4 0.4 0.13 12.6 0.2 2.2 1 1 0 1 1 1 0 Stimulus-sensing domain HET PF06985.6 GAP85063.1 - 2.3e-22 79.6 0.4 5e-22 78.5 0.3 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1767 PF08585.7 GAP85063.1 - 2.2e-05 24.6 0.0 4.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Abhydrolase_3 PF07859.8 GAP85065.1 - 1.4e-15 57.4 0.0 1.8e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.11 GAP85066.1 - 1.7e-26 92.7 32.3 8.2e-16 57.6 1.9 3.0 3 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP85066.1 - 3.3e-10 39.1 2.7 3.3e-10 39.1 1.8 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 GAP85066.1 - 3.4e-09 35.4 7.9 3.4e-09 35.4 5.5 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1914 PF08932.5 GAP85066.1 - 0.0015 18.5 0.1 0.0033 17.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1914) DHH PF01368.15 GAP85066.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 DHH family DUF2530 PF10745.4 GAP85066.1 - 0.57 10.1 11.6 0.21 11.6 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) ADH_N PF08240.7 GAP85067.1 - 9.2e-28 96.1 1.3 1.7e-27 95.3 0.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAP85067.1 - 1.5e-20 73.0 0.1 3.1e-20 72.0 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAP85067.1 - 0.0046 17.8 0.0 0.0089 16.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 GAP85067.1 - 0.029 14.0 0.4 0.059 13.0 0.3 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated DDE_Tnp_IS66_C PF13817.1 GAP85067.1 - 0.16 12.0 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 IS66 C-terminal element p450 PF00067.17 GAP85068.1 - 6.6e-60 202.9 0.0 7.8e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_20 PF00982.16 GAP85069.1 - 1e-148 495.7 0.0 1.6e-148 495.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 GAP85069.1 - 1.4e-75 253.2 0.0 5.3e-75 251.3 0.0 1.9 2 0 0 2 2 2 1 Trehalose-phosphatase HAD PF12710.2 GAP85069.1 - 0.0018 18.4 0.0 0.11 12.6 0.0 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Glyco_trans_1_4 PF13692.1 GAP85069.1 - 0.013 15.6 0.0 0.54 10.4 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 GAP85069.1 - 0.12 11.8 0.0 1 8.7 0.0 2.5 2 1 0 2 2 2 0 Glycosyl transferases group 1 COG5 PF10392.4 GAP85070.1 - 9.6e-39 132.3 3.5 1.2e-38 132.0 0.3 2.5 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Peptidase_M41 PF01434.13 GAP85070.1 - 0.057 12.9 0.8 0.12 11.7 0.3 1.7 2 0 0 2 2 2 0 Peptidase family M41 HCV_core PF01542.13 GAP85071.1 - 4.1 7.8 11.6 2.7 8.4 1.4 2.3 1 1 1 2 2 2 0 Hepatitis C virus core protein DUF3810 PF12725.2 GAP85072.1 - 0.028 13.3 0.1 0.052 12.4 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) Peptidase_M10 PF00413.19 GAP85072.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 1 1 0 1 1 1 0 Matrixin COesterase PF00135.23 GAP85073.1 - 1.4e-88 297.9 0.0 1.9e-88 297.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAP85073.1 - 2.6e-06 27.1 0.2 1.1e-05 25.1 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAP85073.1 - 0.021 14.0 0.7 0.033 13.4 0.5 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAP85073.1 - 0.076 12.7 0.9 0.16 11.7 0.6 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Dabb PF07876.7 GAP85074.1 - 6.3e-05 23.3 0.3 7.6e-05 23.0 0.2 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Lectin_C PF00059.16 GAP85074.1 - 0.018 15.6 0.3 0.022 15.4 0.2 1.1 1 0 0 1 1 1 0 Lectin C-type domain ETC_C1_NDUFA4 PF04800.7 GAP85074.1 - 0.067 13.0 2.0 2.2 8.1 0.1 2.2 1 1 1 2 2 2 0 ETC complex I subunit conserved region Taeniidae_ag PF05596.6 GAP85074.1 - 0.14 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Taeniidae antigen ketoacyl-synt PF00109.21 GAP85075.1 - 2.5e-69 233.5 0.1 5.4e-69 232.4 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 GAP85075.1 - 6.5e-53 179.0 0.1 1.6e-52 177.8 0.1 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 GAP85075.1 - 1.1e-41 143.2 0.0 3.6e-41 141.5 0.0 1.8 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 GAP85075.1 - 5.4e-41 140.2 0.1 1.2e-40 139.1 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase PS-DH PF14765.1 GAP85075.1 - 6.3e-39 133.8 0.1 1.1e-38 133.1 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.15 GAP85075.1 - 3e-31 108.3 0.0 4.8e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Condensation domain Ketoacyl-synt_C PF02801.17 GAP85075.1 - 6.4e-29 100.2 0.0 1.4e-28 99.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_23 PF13489.1 GAP85075.1 - 9.2e-06 25.4 0.0 2.3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 GAP85075.1 - 3.1e-05 24.1 0.2 9.6e-05 22.5 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 GAP85075.1 - 9.3e-05 22.8 0.0 0.00059 20.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain HxxPF_rpt PF13745.1 GAP85075.1 - 0.00051 20.3 0.2 0.0026 18.0 0.0 2.4 2 0 0 2 2 2 1 HxxPF-repeated domain Ubie_methyltran PF01209.13 GAP85075.1 - 0.0024 17.0 0.0 0.0044 16.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 GAP85075.1 - 0.0027 17.3 0.0 0.0072 15.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 GAP85075.1 - 0.0041 16.1 0.0 0.008 15.1 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 GAP85075.1 - 0.0098 15.5 1.4 0.13 11.9 1.0 2.4 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_11 PF08241.7 GAP85075.1 - 0.045 14.2 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain ATPgrasp_TupA PF14305.1 GAP85075.1 - 0.59 9.3 0.1 3.7 6.7 0.0 2.0 2 0 0 2 2 2 0 TupA-like ATPgrasp 7TMR-DISM_7TM PF07695.6 GAP85076.1 - 0.061 12.9 23.9 0.15 11.7 3.0 2.6 2 1 0 2 2 2 0 7TM diverse intracellular signalling XhlA PF10779.4 GAP85076.1 - 0.15 12.0 0.6 0.26 11.2 0.4 1.4 1 0 0 1 1 1 0 Haemolysin XhlA p450 PF00067.17 GAP85077.1 - 8.4e-54 182.8 0.0 1e-53 182.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 GAP85078.1 - 5.2e-34 117.5 49.8 5.2e-34 117.5 34.5 2.8 2 2 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP85078.1 - 8.1e-12 44.4 19.8 8.1e-12 44.4 13.7 3.1 1 1 2 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 GAP85078.1 - 3.4e-10 38.7 14.8 5e-10 38.2 10.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_3 PF05106.7 GAP85078.1 - 0.044 13.7 1.3 0.2 11.6 0.9 2.2 1 1 0 1 1 1 0 Phage holin family (Lysis protein S) DUF2530 PF10745.4 GAP85078.1 - 0.11 12.4 8.4 0.72 9.8 0.3 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) DUF43 PF01861.11 GAP85078.1 - 0.19 10.7 0.0 0.33 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF43 4HBT_3 PF13622.1 GAP85079.1 - 3.6e-33 115.3 2.6 4.1e-33 115.2 1.8 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily PBP1_TM PF14812.1 GAP85080.1 - 1.4 9.3 12.5 1.5 9.2 8.6 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal APH PF01636.18 GAP85081.1 - 0.0012 18.6 0.1 0.07 12.8 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Prenylcys_lyase PF07156.9 GAP85082.1 - 1.4e-33 116.3 0.0 2.4e-24 85.9 0.0 2.3 2 1 0 2 2 2 2 Prenylcysteine lyase NAD_binding_8 PF13450.1 GAP85082.1 - 1.3e-13 50.7 0.1 3.6e-13 49.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 GAP85082.1 - 4.7e-10 39.1 0.0 1.6e-06 27.5 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 GAP85082.1 - 5.4e-06 25.5 0.1 3e-05 23.1 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAP85082.1 - 6.1e-05 23.1 0.1 0.035 14.1 0.0 2.9 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAP85082.1 - 8.4e-05 22.5 2.1 0.055 13.3 0.4 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAP85082.1 - 0.00013 21.8 0.2 0.00054 19.7 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 GAP85082.1 - 0.023 13.1 1.4 0.18 10.2 0.2 2.1 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 GAP85082.1 - 0.028 13.5 0.2 0.061 12.4 0.1 1.5 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.11 GAP85082.1 - 0.051 13.0 0.8 0.23 10.8 0.2 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 GAP85082.1 - 0.052 12.1 0.3 0.084 11.4 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.22 GAP85082.1 - 0.062 13.7 0.8 0.74 10.2 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 GAP85082.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3433 PF11915.3 GAP85083.1 - 4.6e-30 103.6 28.5 1.7e-20 72.9 4.3 3.3 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) COX2_TM PF02790.10 GAP85083.1 - 0.00092 19.1 5.3 0.45 10.5 0.7 3.2 2 0 0 2 2 2 2 Cytochrome C oxidase subunit II, transmembrane domain SPOUT_MTase PF02590.12 GAP85084.1 - 0.085 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase HD_assoc PF13286.1 GAP85084.1 - 0.092 13.0 0.6 0.49 10.7 0.4 2.1 1 1 0 1 1 1 0 Phosphohydrolase-associated domain 2-Hacid_dh_C PF02826.14 GAP85085.1 - 3.9e-39 133.6 0.0 5.7e-39 133.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAP85085.1 - 1.4e-11 44.0 0.0 1.8e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain TrkA_N PF02254.13 GAP85085.1 - 0.00045 20.1 0.0 0.004 17.1 0.0 2.2 1 1 0 1 1 1 1 TrkA-N domain Gp_dh_N PF00044.19 GAP85085.1 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain F420_oxidored PF03807.12 GAP85085.1 - 0.017 15.5 0.0 0.037 14.4 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.15 GAP85085.1 - 0.023 14.6 0.0 0.088 12.7 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus UDPG_MGDP_dh_C PF03720.10 GAP85085.1 - 0.025 14.7 0.1 8.1 6.6 0.0 3.0 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_7 PF13241.1 GAP85085.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Mito_carr PF00153.22 GAP85086.1 - 1.5e-59 197.7 4.8 9.6e-21 73.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Gp23 PF07068.6 GAP85086.1 - 0.11 11.0 0.2 0.14 10.6 0.1 1.1 1 0 0 1 1 1 0 Major capsid protein Gp23 RINT1_TIP1 PF04437.8 GAP85087.1 - 5e-90 302.4 0.0 6.6e-90 302.0 0.0 1.2 1 0 0 1 1 1 1 RINT-1 / TIP-1 family CRISPR_Cse2 PF09485.5 GAP85087.1 - 0.02 14.9 1.8 0.27 11.2 1.4 2.5 3 0 0 3 3 3 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Myosin_tail_1 PF01576.14 GAP85087.1 - 0.038 11.7 2.0 0.065 10.9 1.4 1.3 1 0 0 1 1 1 0 Myosin tail DUF4164 PF13747.1 GAP85087.1 - 0.36 11.0 8.6 0.13 12.4 2.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) IncA PF04156.9 GAP85087.1 - 3.7 7.1 9.4 2.1 7.8 4.7 2.0 2 1 0 2 2 2 0 IncA protein ABC_tran PF00005.22 GAP85088.1 - 1.8e-33 115.7 0.0 2.6e-17 63.4 0.0 2.7 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 GAP85088.1 - 8.1e-13 48.9 4.6 0.021 14.7 0.0 4.4 2 2 2 4 4 4 4 AAA domain RLI PF04068.10 GAP85088.1 - 1.6e-12 46.7 5.0 1.6e-12 46.7 3.4 1.9 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.14 GAP85088.1 - 3.2e-12 46.1 2.2 0.0003 20.0 0.0 3.9 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 GAP85088.1 - 7.9e-09 35.0 0.0 0.021 13.9 0.0 4.1 4 0 0 4 4 4 1 AAA ATPase domain AAA_17 PF13207.1 GAP85088.1 - 1.4e-06 29.0 1.2 0.13 13.0 0.0 3.5 2 2 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAP85088.1 - 7.6e-06 26.0 0.0 0.0075 16.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 GAP85088.1 - 7.7e-06 26.1 0.1 0.024 14.8 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 GAP85088.1 - 3.2e-05 23.3 0.2 0.07 12.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4 PF00037.22 GAP85088.1 - 3.8e-05 23.0 2.8 3.8e-05 23.0 1.9 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain NACHT PF05729.7 GAP85088.1 - 0.00012 21.8 0.1 0.14 11.8 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_23 PF13476.1 GAP85088.1 - 0.00013 22.3 0.1 0.0084 16.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 GAP85088.1 - 0.0002 21.4 0.1 0.21 11.7 0.0 2.8 3 0 0 3 3 2 1 RNA helicase MobB PF03205.9 GAP85088.1 - 0.00021 20.9 1.7 0.036 13.7 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 GAP85088.1 - 0.00021 20.4 1.3 0.64 9.1 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function, DUF258 SRP54 PF00448.17 GAP85088.1 - 0.00024 20.5 3.2 0.022 14.1 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 GAP85088.1 - 0.00027 20.3 0.1 1.1 8.6 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 GAP85088.1 - 0.00045 20.1 0.0 0.15 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 GAP85088.1 - 0.00059 19.4 0.2 0.021 14.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Fer4_21 PF14697.1 GAP85088.1 - 0.00098 18.9 10.5 0.0021 17.8 7.3 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain VirE PF05272.6 GAP85088.1 - 0.0016 17.9 0.1 1.9 7.9 0.0 2.9 3 0 0 3 3 2 1 Virulence-associated protein E AAA_18 PF13238.1 GAP85088.1 - 0.0023 18.2 1.8 1.4 9.2 0.1 3.0 2 2 0 2 2 2 1 AAA domain AAA_13 PF13166.1 GAP85088.1 - 0.0024 16.4 0.0 0.0024 16.4 0.0 2.5 4 1 0 4 4 2 1 AAA domain NB-ARC PF00931.17 GAP85088.1 - 0.0027 16.6 0.0 0.15 10.9 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Miro PF08477.8 GAP85088.1 - 0.003 18.0 0.1 1.5 9.3 0.0 3.1 3 0 0 3 3 3 1 Miro-like protein AAA_16 PF13191.1 GAP85088.1 - 0.0047 16.9 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Fer4_6 PF12837.2 GAP85088.1 - 0.0056 16.5 1.0 0.0056 16.5 0.7 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_30 PF13604.1 GAP85088.1 - 0.0067 16.0 0.0 3.8 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 GAP85088.1 - 0.0086 15.4 0.1 2 7.7 0.0 2.5 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.1 GAP85088.1 - 0.0096 15.8 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 GAP85088.1 - 0.043 12.4 0.1 1.2 7.7 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 GAP85088.1 - 0.06 13.2 0.1 17 5.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.16 GAP85088.1 - 0.084 12.0 0.7 0.26 10.3 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Fer4_8 PF13183.1 GAP85088.1 - 0.13 12.3 8.7 0.34 10.9 6.1 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain AAA_5 PF07728.9 GAP85088.1 - 0.21 11.2 3.2 3.8 7.2 0.0 3.2 3 1 1 4 4 3 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 GAP85088.1 - 0.29 10.7 0.0 0.29 10.7 0.0 2.5 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.4 GAP85088.1 - 0.51 9.8 4.0 0.65 9.4 0.1 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 GAP85088.1 - 0.88 9.2 5.1 7.4 6.2 0.1 2.8 3 0 0 3 3 2 0 NTPase Fer4_2 PF12797.2 GAP85088.1 - 1 9.4 12.1 0.92 9.5 1.4 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_10 PF13237.1 GAP85088.1 - 1.1 9.0 14.8 0.067 12.9 1.0 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.2 GAP85088.1 - 2.6 8.5 13.9 0.12 12.7 1.7 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 GAP85088.1 - 2.7 8.3 13.5 0.17 12.1 1.6 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain p450 PF00067.17 GAP85089.1 - 7e-65 219.3 0.0 8.6e-65 219.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 GAP85090.1 - 1.1e-36 126.3 0.1 2.1e-20 72.6 0.0 2.7 1 1 1 2 2 2 2 Cytochrome P450 Terpene_synth_C PF03936.11 GAP85091.1 - 3.8e-08 32.9 2.2 7e-08 32.0 1.5 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Sulfotransfer_3 PF13469.1 GAP85092.1 - 0.0097 16.8 2.7 0.027 15.4 1.9 1.8 1 1 0 1 1 1 1 Sulfotransferase family HET PF06985.6 GAP85093.1 - 3.3e-22 79.1 9.8 5.7e-19 68.6 2.4 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HNH_2 PF13391.1 GAP85094.1 - 3.3e-09 36.3 0.0 7.1e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Plasmid_stabil PF05016.9 GAP85094.1 - 0.1 12.9 0.0 3.7 8.0 0.0 2.7 3 0 0 3 3 3 0 Plasmid stabilisation system protein CN_hydrolase PF00795.17 GAP85095.1 - 3.8e-33 114.3 0.0 5e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase p450 PF00067.17 GAP85097.1 - 1.9e-29 102.5 0.0 3.5e-29 101.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 GAP85098.1 - 3.7e-09 35.6 0.0 2.8e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 Cytochrome P450 ABC2_membrane PF01061.19 GAP85100.1 - 5.1e-75 251.2 42.3 1e-41 142.4 12.1 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 GAP85100.1 - 3.9e-33 114.6 0.0 3e-15 56.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 GAP85100.1 - 3.8e-25 87.5 0.0 1.7e-24 85.4 0.0 2.1 2 0 0 2 2 2 1 CDR ABC transporter AAA_25 PF13481.1 GAP85100.1 - 4.9e-06 26.0 0.4 0.035 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 GAP85100.1 - 6.8e-06 25.3 37.2 0.0025 16.8 13.0 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein SMC_N PF02463.14 GAP85100.1 - 0.0023 17.1 0.0 1.1 8.4 0.0 3.4 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 GAP85100.1 - 0.0027 16.9 0.2 0.013 14.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 GAP85100.1 - 0.0052 16.2 0.4 0.0052 16.2 0.3 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 GAP85100.1 - 0.0061 16.5 2.2 0.021 14.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 GAP85100.1 - 0.017 15.4 0.2 0.17 12.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_trans_N PF14510.1 GAP85100.1 - 0.029 14.4 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal FtsK_SpoIIIE PF01580.13 GAP85100.1 - 0.035 13.5 0.2 1.1 8.6 0.0 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family SbcCD_C PF13558.1 GAP85100.1 - 0.056 13.3 0.0 5.3 7.0 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 GAP85100.1 - 0.076 12.9 0.1 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.1 GAP85100.1 - 0.11 12.3 0.5 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 GAP85100.1 - 0.11 13.2 0.1 0.87 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 GAP85100.1 - 0.14 11.7 1.7 6.4 6.3 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Thymidylate_kin PF02223.12 GAP85100.1 - 0.19 11.0 0.0 0.37 10.1 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase NACHT PF05729.7 GAP85100.1 - 0.37 10.4 4.0 7.4 6.2 0.1 3.6 3 0 0 3 3 3 0 NACHT domain p450 PF00067.17 GAP85101.1 - 9.6e-32 110.0 0.0 4.9e-31 107.7 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 AAA PF00004.24 GAP85103.1 - 4.1e-17 62.6 0.0 8.4e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 GAP85103.1 - 4e-05 24.4 0.0 0.00017 22.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAP85103.1 - 0.00028 21.0 0.2 0.0014 18.7 0.1 2.2 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 GAP85103.1 - 0.00047 19.9 0.0 0.00098 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 GAP85103.1 - 0.001 19.4 0.2 0.0052 17.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAP85103.1 - 0.0034 17.3 0.0 0.011 15.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 GAP85103.1 - 0.018 14.0 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 GAP85103.1 - 0.02 14.6 0.1 0.047 13.4 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 GAP85103.1 - 0.024 14.5 0.0 0.06 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 GAP85103.1 - 0.029 14.2 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 GAP85103.1 - 0.047 13.6 0.2 0.2 11.6 0.1 2.0 1 1 0 2 2 2 0 AAA domain AIM24 PF01987.12 GAP85105.1 - 1.3e-45 155.5 0.0 1.6e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 YqjK PF13997.1 GAP85105.1 - 0.11 12.7 3.2 0.18 11.9 0.0 2.9 3 1 1 4 4 4 0 YqjK-like protein MFS_1 PF07690.11 GAP85106.1 - 3.2e-31 108.3 58.7 2.1e-27 95.7 23.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 GAP85106.1 - 0.0036 17.0 5.9 0.017 14.9 0.2 3.0 2 0 0 2 2 2 1 MFS_1 like family SpoA PF01052.15 GAP85107.1 - 0.086 12.4 0.2 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Surface presentation of antigens (SPOA) DUF2945 PF11160.3 GAP85108.1 - 0.0026 17.5 1.6 0.0088 15.8 1.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2945) ECH PF00378.15 GAP85109.1 - 8.4e-44 149.5 0.0 6.9e-41 139.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family Ank_2 PF12796.2 GAP85110.1 - 1.7e-15 57.0 0.0 2.4e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAP85110.1 - 1.5e-14 53.9 0.8 8e-08 32.5 0.1 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 GAP85110.1 - 1.1e-13 50.2 0.1 2.6e-09 36.4 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 GAP85110.1 - 7e-12 45.1 0.7 1.6e-10 40.8 0.1 2.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP85110.1 - 1e-10 40.7 0.0 1.7e-06 27.7 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Peptidase_M6 PF05547.6 GAP85111.1 - 5.9e-08 31.2 0.7 0.002 16.2 0.0 2.1 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 Peptidase_S28 PF05577.7 GAP85112.1 - 1e-43 149.5 0.6 1.2e-34 119.6 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 DUF1573 PF07610.6 GAP85113.1 - 6.4 6.4 9.9 0.43 10.1 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1573) Sec7 PF01369.15 GAP85114.1 - 6.7e-44 149.8 0.0 1.5e-43 148.6 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 GAP85114.1 - 5.8e-20 71.6 0.0 1.2e-19 70.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain AA_permease_2 PF13520.1 GAP85115.1 - 1.3e-46 158.9 43.6 1.8e-46 158.5 30.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAP85115.1 - 1.8e-23 82.6 35.0 2.5e-23 82.2 24.3 1.1 1 0 0 1 1 1 1 Amino acid permease ketoacyl-synt PF00109.21 GAP85116.1 - 7.2e-65 218.9 0.1 1.2e-64 218.2 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 GAP85116.1 - 1.1e-34 118.8 0.1 2.9e-34 117.4 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 GAP85116.1 - 2e-33 116.0 0.0 2e-32 112.7 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain Thioesterase PF00975.15 GAP85116.1 - 1.7e-21 77.5 0.0 7.9e-21 75.3 0.0 2.2 2 1 0 2 2 2 1 Thioesterase domain PS-DH PF14765.1 GAP85116.1 - 3.1e-16 59.3 0.0 6.2e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 GAP85116.1 - 5e-08 33.0 0.2 1.9e-07 31.2 0.1 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 GAP85116.1 - 0.043 12.8 0.3 0.13 11.1 0.0 1.8 2 0 0 2 2 2 0 Thiolase, N-terminal domain Amidohydro_4 PF13147.1 GAP85117.1 - 4.5e-13 49.8 19.3 5.6e-12 46.2 0.1 3.8 2 2 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 GAP85117.1 - 7.9e-06 25.7 0.1 5.9e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 GAP85117.1 - 2.2e-05 24.1 0.1 0.0001 22.0 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 GAP85117.1 - 0.00016 21.0 0.0 0.00016 21.0 0.0 2.3 3 1 0 3 3 3 1 Amidohydrolase family DUF4131 PF13567.1 GAP85117.1 - 0.027 13.8 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) p450 PF00067.17 GAP85118.1 - 4.1e-37 127.7 0.0 5.7e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_4 PF01063.14 GAP85119.1 - 1.5e-08 34.3 0.0 1.8e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV NUDIX PF00293.23 GAP85120.1 - 1.6e-07 31.0 0.0 3.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain MFS_1 PF07690.11 GAP85121.1 - 3.6e-23 81.8 61.4 3.8e-21 75.2 23.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF872 PF05915.7 GAP85121.1 - 6.7 6.6 8.6 29 4.5 0.4 3.5 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Lipase_GDSL_2 PF13472.1 GAP85122.1 - 4.3e-08 33.5 0.0 8.3e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipoprotein_2 PF00921.12 GAP85122.1 - 0.06 13.3 0.2 0.06 13.3 0.1 1.9 2 0 0 2 2 2 0 Borrelia lipoprotein DMRL_synthase PF00885.14 GAP85122.1 - 0.097 12.3 1.7 15 5.2 0.0 3.6 3 1 1 4 4 4 0 6,7-dimethyl-8-ribityllumazine synthase Mucin PF01456.12 GAP85122.1 - 0.77 9.5 9.2 1.3 8.7 6.4 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF809 PF05663.6 GAP85122.1 - 6.3 6.7 5.9 3.5 7.5 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF809) PIP5K PF01504.13 GAP85123.1 - 8.8e-31 106.8 0.0 1.1e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase MOSC PF03473.12 GAP85124.1 - 7.4e-18 64.2 0.0 1.7e-17 63.1 0.0 1.6 2 0 0 2 2 2 1 MOSC domain 3-alpha PF03475.9 GAP85124.1 - 1.4e-10 40.7 0.0 2.5e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 3-alpha domain Fer2 PF00111.22 GAP85124.1 - 2e-09 37.0 1.1 3.8e-09 36.1 0.8 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.16 GAP85124.1 - 8.4e-06 26.3 0.1 4e-05 24.1 0.1 2.2 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 GAP85124.1 - 0.0033 17.4 0.0 0.0069 16.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 GAP85124.1 - 0.021 14.6 0.1 4.2 7.2 0.0 2.3 2 0 0 2 2 2 0 Ferric reductase NAD binding domain AAA PF00004.24 GAP85125.1 - 7.9e-16 58.4 0.0 1.5e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAP85125.1 - 0.0004 20.1 0.0 0.0053 16.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 GAP85125.1 - 0.00047 20.3 0.1 0.004 17.2 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAP85125.1 - 0.0022 17.7 0.0 0.0062 16.2 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Torsin PF06309.6 GAP85125.1 - 0.006 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA_17 PF13207.1 GAP85125.1 - 0.016 16.0 0.0 0.054 14.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 GAP85125.1 - 0.017 15.0 0.0 0.053 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 GAP85125.1 - 0.041 13.8 0.0 0.096 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 GAP85125.1 - 0.054 13.0 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 GAP85125.1 - 0.074 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 GAP85125.1 - 0.078 12.3 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 GAP85125.1 - 0.088 12.2 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain ORC6 PF05460.8 GAP85126.1 - 0.071 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Fimbrial_PilY2 PF14481.1 GAP85126.1 - 0.082 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 Gpi1 PF05024.10 GAP85127.1 - 3.9e-64 215.8 8.5 3.9e-64 215.8 5.9 1.6 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) DNA_pol_A_exo1 PF01612.15 GAP85128.1 - 2.4e-40 137.8 0.1 3.6e-40 137.3 0.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 GAP85128.1 - 2.4e-24 85.4 0.1 5.6e-24 84.2 0.1 1.7 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 GAP85128.1 - 5.9e-14 51.5 0.0 1.2e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 HRDC domain SRP-alpha_N PF04086.8 GAP85128.1 - 1.7 7.9 18.4 3.1 7.1 12.7 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CDC45 PF02724.9 GAP85128.1 - 7.9 4.3 15.0 15 3.4 10.4 1.4 1 0 0 1 1 1 0 CDC45-like protein UPF0203 PF05254.7 GAP85129.1 - 9.6e-27 92.6 2.2 1.1e-26 92.3 1.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.8 GAP85129.1 - 0.011 15.7 1.7 0.033 14.2 1.1 1.7 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) DUF2732 PF10809.3 GAP85129.1 - 0.029 13.8 0.2 0.041 13.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) Cmc1 PF08583.5 GAP85129.1 - 0.083 12.6 0.2 0.083 12.6 0.2 2.5 2 1 1 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.11 GAP85129.1 - 0.091 12.7 2.3 2.8 7.9 0.2 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Curto_V2 PF07325.6 GAP85129.1 - 0.15 11.6 1.3 0.17 11.5 0.9 1.2 1 0 0 1 1 1 0 Curtovirus V2 protein COX6B PF02297.12 GAP85129.1 - 1.8 8.6 5.8 1.4 8.9 0.2 2.0 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb PTR2 PF00854.16 GAP85130.1 - 3e-27 95.3 17.3 1.9e-26 92.7 8.2 3.0 1 1 1 2 2 2 2 POT family DUF1469 PF07332.6 GAP85130.1 - 0.0011 18.7 0.7 0.0011 18.7 0.5 3.7 3 1 1 4 4 4 1 Protein of unknown function (DUF1469) CcmH PF03918.9 GAP85130.1 - 0.0044 16.0 1.3 1.7 7.6 0.0 3.0 2 1 0 2 2 2 2 Cytochrome C biogenesis protein Herpes_US9 PF06072.6 GAP85130.1 - 0.18 11.6 1.0 2.2 8.2 0.1 2.9 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Peptidase_M28 PF04389.12 GAP85132.1 - 7.8e-34 116.9 0.0 1.3e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 GAP85132.1 - 1e-12 47.6 0.7 1.9e-12 46.7 0.5 1.5 1 0 0 1 1 1 1 PA domain Y_phosphatase PF00102.22 GAP85133.1 - 9.7e-50 169.0 0.0 1.4e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 GAP85133.1 - 0.00023 21.2 0.0 0.00043 20.3 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 GAP85133.1 - 0.0023 18.1 0.0 0.0067 16.6 0.0 1.8 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 GAP85133.1 - 0.045 13.3 0.0 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Folliculin PF11704.3 GAP85135.1 - 2.1e-28 99.0 0.0 3.5e-27 95.0 0.0 2.7 1 1 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport MFS_1 PF07690.11 GAP85136.1 - 2.6e-32 111.9 27.7 2.6e-32 111.9 19.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DLH PF01738.13 GAP85138.1 - 3.4e-06 26.5 0.0 5.5e-06 25.8 0.0 1.4 1 1 1 2 2 2 1 Dienelactone hydrolase family NIF3 PF01784.13 GAP85138.1 - 0.025 14.1 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) DLH PF01738.13 GAP85139.1 - 6.5e-11 41.9 0.3 6.8e-11 41.8 0.2 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 GAP85139.1 - 0.12 12.0 0.1 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Fungal_trans PF04082.13 GAP85140.1 - 6.1e-12 44.9 0.1 1.1e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP85140.1 - 7.4e-09 35.3 7.7 1.4e-08 34.4 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 GAP85141.1 - 7.6e-25 87.3 30.1 1.1e-24 86.8 20.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP85141.1 - 9.3e-05 21.1 7.9 9.3e-05 21.1 5.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 GAP85141.1 - 0.00044 19.9 7.6 0.049 13.4 1.7 3.1 3 0 0 3 3 3 2 MFS_1 like family Fig1 PF12351.3 GAP85142.1 - 3.2e-58 196.6 2.9 3.2e-58 196.6 2.0 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 GAP85142.1 - 2.2e-10 40.4 7.8 2.8e-10 40.1 5.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 GAP85142.1 - 4.2e-06 25.8 2.8 4.2e-06 25.8 1.9 1.7 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) DUF202 PF02656.10 GAP85142.1 - 0.11 12.7 8.8 0.11 12.7 0.1 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF202) DUF1673 PF07895.6 GAP85142.1 - 0.81 9.1 4.9 0.54 9.7 0.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1673) DUF2976 PF11190.3 GAP85142.1 - 2.1 7.9 0.0 2.1 7.9 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2976) ODV-E18 PF10717.4 GAP85142.1 - 9.9 5.6 11.0 1.3 8.4 1.2 2.8 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 MFS_1 PF07690.11 GAP85143.1 - 3.6e-41 141.0 47.0 2.4e-40 138.3 31.5 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAP85143.1 - 3.6e-17 61.8 25.3 3.7e-17 61.7 17.0 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAP85143.1 - 2.8e-11 42.6 8.7 2.8e-11 42.6 6.0 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter p450 PF00067.17 GAP85144.1 - 1.7e-26 92.7 0.0 2.4e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Rifin_STEVOR PF02009.11 GAP85145.1 - 0.041 13.5 0.0 0.052 13.1 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family Baculo_11_kDa PF06143.6 GAP85145.1 - 0.92 8.9 6.3 1.7 8.0 4.3 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF983 PF06170.7 GAP85145.1 - 1.3 9.2 4.5 1.3 9.1 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Glyco_hydro_47 PF01532.15 GAP85146.1 - 2.6e-170 566.9 0.1 3.2e-170 566.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AA_permease PF00324.16 GAP85148.1 - 1.8e-123 412.4 45.7 2e-123 412.2 31.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAP85148.1 - 1.8e-28 99.2 51.2 2.5e-28 98.7 35.5 1.1 1 0 0 1 1 1 1 Amino acid permease GMC_oxred_C PF05199.8 GAP85149.1 - 1.2e-25 90.5 0.0 2.4e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 GAP85149.1 - 7.7e-18 64.6 0.0 6.6e-14 51.7 0.0 3.1 3 0 0 3 3 3 2 GMC oxidoreductase Lycopene_cycl PF05834.7 GAP85149.1 - 0.00026 20.0 0.0 0.00036 19.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAP85149.1 - 0.0011 17.9 0.0 0.058 12.2 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 GAP85149.1 - 0.0043 16.9 0.0 0.044 13.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP85149.1 - 0.021 14.8 0.0 0.078 13.0 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAP85149.1 - 0.18 10.2 0.0 0.32 9.4 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein ADH_zinc_N PF00107.21 GAP85150.1 - 2.7e-32 111.0 2.2 5.2e-32 110.1 1.5 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAP85150.1 - 1.4e-18 68.0 0.8 3e-18 66.9 0.2 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP85150.1 - 1.6e-12 47.0 0.0 5e-12 45.5 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 GAP85150.1 - 0.0036 17.3 0.1 0.01 15.8 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain AlaDh_PNT_C PF01262.16 GAP85150.1 - 0.0051 16.3 0.1 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain WSC PF01822.14 GAP85152.1 - 3.3e-10 39.7 7.5 3.3e-10 39.7 5.2 1.9 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.5 GAP85152.1 - 2.3e-07 30.0 0.5 4.4e-07 29.1 0.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4366 PF14283.1 GAP85152.1 - 2.5e-05 23.7 0.7 4.5e-05 22.9 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) Podoplanin PF05808.6 GAP85152.1 - 0.0003 20.3 0.8 0.0005 19.6 0.6 1.3 1 0 0 1 1 1 1 Podoplanin TMEM154 PF15102.1 GAP85152.1 - 0.0036 17.0 0.2 0.0056 16.3 0.1 1.2 1 0 0 1 1 1 1 TMEM154 protein family Glycophorin_A PF01102.13 GAP85152.1 - 0.0084 15.8 0.2 0.014 15.1 0.2 1.3 1 0 0 1 1 1 1 Glycophorin A SSP160 PF06933.6 GAP85152.1 - 0.0086 14.1 2.7 0.012 13.5 1.9 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 DUF1191 PF06697.7 GAP85152.1 - 0.009 14.8 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Peptidase_M56 PF05569.6 GAP85152.1 - 0.0095 14.9 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF4448 PF14610.1 GAP85152.1 - 0.016 14.6 0.1 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Alpha_GJ PF03229.8 GAP85152.1 - 0.066 13.5 2.3 0.13 12.5 1.6 1.6 1 0 0 1 1 1 0 Alphavirus glycoprotein J Adeno_E3_CR2 PF02439.10 GAP85152.1 - 0.21 11.1 1.4 0.39 10.3 1.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Herpes_capsid PF06112.6 GAP85152.1 - 0.53 10.3 4.6 0.38 10.8 1.5 1.9 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein DUF3042 PF11240.3 GAP85152.1 - 2 8.2 6.0 7 6.5 4.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3042) DUF1446 PF07287.6 GAP85154.1 - 1.6e-105 352.5 0.2 2.3e-105 352.0 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) DUF1800 PF08811.6 GAP85154.1 - 0.059 12.2 0.1 0.08 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) FAD_binding_4 PF01565.18 GAP85155.1 - 9e-18 64.0 3.5 9e-18 64.0 2.4 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 GAP85155.1 - 1.7e-11 43.8 0.0 3.3e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like APH PF01636.18 GAP85156.1 - 4.3e-36 124.8 0.1 7.9e-36 123.9 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 GAP85156.1 - 6.4e-07 28.7 0.0 1.2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 GAP85156.1 - 0.00089 18.8 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 GAP85156.1 - 0.00092 17.9 0.0 0.016 13.8 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1679) RIO1 PF01163.17 GAP85156.1 - 0.014 14.7 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Acyl-CoA_dh_N PF02771.11 GAP85157.1 - 3.3e-09 37.3 0.3 9.2e-09 35.8 0.2 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 GAP85157.1 - 0.0096 15.4 0.8 0.02 14.3 0.6 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 GAP85158.1 - 3.7e-19 69.2 1.5 2.6e-18 66.5 1.0 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 GAP85158.1 - 4.7e-07 30.1 2.8 1.4e-06 28.5 1.9 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain FHA PF00498.21 GAP85159.1 - 1.3e-13 50.7 0.0 2.5e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 FHA domain MIP-T3 PF10243.4 GAP85159.1 - 7.7 4.8 29.4 10 4.4 20.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 AAA_16 PF13191.1 GAP85160.1 - 4.1e-08 33.4 0.0 1.5e-07 31.5 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain DUF676 PF05057.9 GAP85160.1 - 0.016 14.5 0.0 0.034 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.8 GAP85160.1 - 0.016 14.8 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Dot_icm_IcmQ PF09475.5 GAP85160.1 - 0.022 13.9 0.0 0.052 12.7 0.0 1.5 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) Arch_ATPase PF01637.13 GAP85160.1 - 0.041 13.5 0.1 0.17 11.5 0.0 2.0 3 0 0 3 3 3 0 Archaeal ATPase SpoIIE PF07228.7 GAP85162.1 - 0.033 13.8 0.0 0.041 13.5 0.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Glyco_hydro_88 PF07470.8 GAP85164.1 - 5.8e-09 35.4 0.4 7.8e-09 35.0 0.3 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 HET PF06985.6 GAP85165.1 - 7.6e-12 45.5 1.0 2.2e-11 44.1 0.7 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Alpha_L_fucos PF01120.12 GAP85165.1 - 0.0026 16.7 0.1 0.0041 16.0 0.0 1.2 1 0 0 1 1 1 1 Alpha-L-fucosidase FTA2 PF13095.1 GAP85166.1 - 1.5e-23 83.5 0.0 4.5e-23 81.9 0.0 1.7 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Corona_nucleoca PF00937.13 GAP85166.1 - 0.052 12.4 0.5 0.072 12.0 0.4 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein UCH PF00443.24 GAP85168.1 - 5.3e-39 133.9 0.0 3.6e-38 131.2 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAP85168.1 - 3.6e-17 62.7 0.2 1.8e-09 37.4 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Josephin PF02099.12 GAP85168.1 - 6.3e-05 22.6 0.4 0.00019 21.1 0.0 1.9 2 0 0 2 2 2 1 Josephin DUF4050 PF13259.1 GAP85168.1 - 0.034 14.0 0.0 0.097 12.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) PUB PF09409.5 GAP85168.1 - 0.046 13.4 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 PUB domain Tim17 PF02466.14 GAP85169.1 - 3.1e-13 49.8 9.5 4.1e-13 49.4 6.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TraT PF05818.7 GAP85169.1 - 2.2 7.6 9.6 0.92 8.8 2.6 2.0 1 1 1 2 2 2 0 Enterobacterial TraT complement resistance protein Gly-zipper_OmpA PF13436.1 GAP85169.1 - 2.5 7.8 8.5 2 8.0 1.6 2.2 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain DUF2410 PF10307.4 GAP85171.1 - 3.6e-77 258.2 0.0 4.9e-77 257.7 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) DUF3104 PF11302.3 GAP85171.1 - 0.061 12.7 0.2 0.061 12.7 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3104) DNA_primase_S PF01896.14 GAP85172.1 - 6.6e-54 181.6 0.0 1.1e-53 180.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit MFS_1 PF07690.11 GAP85175.1 - 2.5e-33 115.2 52.9 2.8e-32 111.8 36.3 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAP85175.1 - 4.1e-12 45.0 21.0 6.2e-12 44.5 13.9 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAP85175.1 - 1.7e-07 30.2 18.4 1.7e-07 30.2 12.7 3.6 1 1 2 4 4 4 2 Sugar (and other) transporter EthD PF07110.6 GAP85176.1 - 5.1e-05 24.1 0.5 7.1e-05 23.6 0.3 1.2 1 0 0 1 1 1 1 EthD domain ADH_N PF08240.7 GAP85178.1 - 0.0018 17.9 0.0 0.021 14.5 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Zn_clus PF00172.13 GAP85179.1 - 0.0013 18.6 6.3 0.0023 17.7 4.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1396 PF07161.8 GAP85179.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1396) Elf1 PF05129.8 GAP85179.1 - 0.15 11.7 1.6 0.3 10.7 0.6 1.9 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like CFEM PF05730.6 GAP85180.1 - 9.1e-14 51.0 9.3 1.5e-13 50.3 6.4 1.3 1 0 0 1 1 1 1 CFEM domain Abhydrolase_5 PF12695.2 GAP85181.1 - 2.4e-11 43.6 0.0 2.8e-10 40.1 0.0 2.5 2 2 1 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP85181.1 - 5.8e-11 42.7 0.7 1.2e-10 41.6 0.2 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF1100 PF06500.6 GAP85181.1 - 6.3e-11 41.4 0.0 1.4e-10 40.3 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.16 GAP85181.1 - 0.01 15.0 0.0 0.024 13.8 0.0 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 GAP85181.1 - 0.045 13.6 0.0 0.69 9.8 0.0 2.6 3 0 0 3 3 3 0 Putative lysophospholipase ketoacyl-synt PF00109.21 GAP85182.1 - 3e-71 239.8 0.0 5.4e-71 239.0 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.23 GAP85182.1 - 4.1e-67 226.3 0.1 2.7e-66 223.7 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme KR PF08659.5 GAP85182.1 - 1.1e-53 181.5 0.1 4.6e-52 176.3 0.0 2.8 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 GAP85182.1 - 6.1e-52 176.9 0.0 1.1e-51 176.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Condensation PF00668.15 GAP85182.1 - 1.9e-50 171.4 0.0 2.9e-50 170.8 0.0 1.2 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 GAP85182.1 - 2.2e-46 157.8 0.0 3.4e-43 147.4 0.0 2.8 2 0 0 2 2 2 2 short chain dehydrogenase PS-DH PF14765.1 GAP85182.1 - 5.6e-44 150.4 0.0 9.7e-44 149.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 GAP85182.1 - 6.9e-34 116.2 0.1 1.4e-33 115.2 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 GAP85182.1 - 1.3e-31 109.3 0.0 3.1e-31 108.2 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 GAP85182.1 - 3.7e-13 49.5 0.6 3.9e-08 33.4 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.16 GAP85182.1 - 1.9e-10 40.6 0.0 6.7e-08 32.2 0.0 2.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family HxxPF_rpt PF13745.1 GAP85182.1 - 2.2e-08 34.3 0.0 5.4e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 HxxPF-repeated domain 3Beta_HSD PF01073.14 GAP85182.1 - 1e-05 24.4 0.0 0.085 11.5 0.0 3.2 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 GAP85182.1 - 6.2e-05 23.8 0.0 0.00067 20.5 0.0 2.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF268 PF03269.9 GAP85182.1 - 0.0036 16.9 0.0 0.0098 15.4 0.0 1.7 1 0 0 1 1 1 1 Caenorhabditis protein of unknown function, DUF268 NmrA PF05368.8 GAP85182.1 - 0.0065 15.7 0.1 0.94 8.6 0.0 3.0 3 0 0 3 3 3 1 NmrA-like family Thiolase_N PF00108.18 GAP85182.1 - 0.0097 14.9 0.0 0.023 13.6 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain NAD_binding_10 PF13460.1 GAP85182.1 - 0.039 13.9 0.0 0.42 10.5 0.0 2.8 4 0 0 4 4 2 0 NADH(P)-binding Methyltransf_31 PF13847.1 GAP85182.1 - 0.089 12.3 0.0 0.5 9.9 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 GAP85182.1 - 0.23 11.1 0.0 0.68 9.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Spt20 PF12090.3 GAP85183.1 - 0.27 10.5 6.5 0.23 10.7 3.6 1.6 2 0 0 2 2 2 0 Spt20 family DUF4407 PF14362.1 GAP85183.1 - 1.1 8.1 7.6 7 5.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) BAF1_ABF1 PF04684.8 GAP85183.1 - 1.9 7.2 19.9 3.2 6.5 13.8 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Suf PF05843.9 GAP85183.1 - 6.7 6.3 15.9 0.64 9.6 7.9 1.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Ebola_NP PF05505.7 GAP85183.1 - 6.8 4.6 12.1 12 3.8 8.4 1.3 1 0 0 1 1 1 0 Ebola nucleoprotein DUF4140 PF13600.1 GAP85183.1 - 6.9 7.1 12.3 2.1 8.8 0.4 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TAP42 PF04177.7 GAP85183.1 - 8.2 5.2 15.2 2.8 6.8 0.2 2.2 2 0 0 2 2 2 0 TAP42-like family Terpene_synth_C PF03936.11 GAP85184.1 - 3.3e-12 46.2 0.0 4.3e-09 35.9 0.0 2.1 1 1 1 2 2 2 2 Terpene synthase family, metal binding domain DUF2236 PF09995.4 GAP85185.1 - 1.6e-33 116.0 6.2 2.3e-33 115.4 4.3 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Lgl_C PF08596.5 GAP85186.1 - 3e-114 381.5 0.0 4.4e-114 381.0 0.0 1.2 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal Glyco_hydro_3 PF00933.16 GAP85186.1 - 1.1e-93 313.5 0.0 1.6e-93 312.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAP85186.1 - 3.7e-53 180.3 1.3 3.7e-53 180.3 0.9 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAP85186.1 - 2.9e-16 59.1 0.3 9.2e-16 57.5 0.1 2.1 2 0 0 2 2 2 1 Fibronectin type III-like domain WD40 PF00400.27 GAP85186.1 - 0.0013 18.5 3.0 0.73 9.8 0.0 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat Nup160 PF11715.3 GAP85186.1 - 0.1 10.7 0.0 4.3 5.3 0.0 2.2 1 1 0 2 2 2 0 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 GAP85186.1 - 0.2 11.2 0.0 1.3 8.6 0.0 2.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Mito_carr PF00153.22 GAP85187.1 - 7.7e-44 147.3 1.0 1.4e-17 63.1 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Adeno_E3B PF03376.9 GAP85187.1 - 0.16 11.9 0.1 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E3B protein SNF2_N PF00176.18 GAP85188.1 - 1.1e-67 228.0 0.0 1.4e-67 227.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 GAP85188.1 - 3.2e-60 203.2 1.6 8.1e-60 201.9 1.1 1.7 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 GAP85188.1 - 1.1e-12 47.6 0.0 4.1e-12 45.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 GAP85188.1 - 3.4e-05 22.8 0.0 0.00016 20.5 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 GAP85188.1 - 0.00058 19.7 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 GAP85188.1 - 0.049 13.7 0.2 0.45 10.6 0.1 2.5 2 1 0 2 2 2 0 AAA domain Sel1 PF08238.7 GAP85189.1 - 2.8e-15 56.3 29.6 7.9e-08 32.7 0.1 7.4 7 0 0 7 7 7 4 Sel1 repeat TPR_2 PF07719.12 GAP85189.1 - 0.024 14.5 1.2 1.2 9.2 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAP85189.1 - 0.036 13.8 2.1 0.057 13.2 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAP85189.1 - 0.072 12.7 2.4 0.099 12.2 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAP85189.1 - 0.13 12.1 0.0 0.42 10.5 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAP85189.1 - 0.42 11.3 6.6 4.2 8.2 0.0 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 GAP85189.1 - 2.8 7.6 7.5 0.88 9.2 0.2 3.1 3 0 0 3 3 3 0 TPR repeat TPR_6 PF13174.1 GAP85189.1 - 5.9 7.5 10.6 0.54 10.8 0.1 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat SAC3_GANP PF03399.11 GAP85190.1 - 2.5e-27 95.8 0.0 3.7e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 GAP85190.1 - 3.2e-21 75.5 0.0 6e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Coatomer_WDAD PF04053.9 GAP85191.1 - 8.5e-151 502.6 0.2 1.5e-150 501.9 0.0 1.5 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.6 GAP85191.1 - 7e-83 278.5 0.0 9.7e-83 278.0 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 GAP85191.1 - 3.3e-50 166.2 14.9 6.4e-09 35.3 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Clathrin PF00637.15 GAP85191.1 - 0.027 14.0 0.2 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 Region in Clathrin and VPS Nup160 PF11715.3 GAP85191.1 - 0.053 11.6 3.4 0.29 9.2 0.0 2.8 2 1 1 3 3 3 0 Nucleoporin Nup120/160 UDP-g_GGTase PF06427.6 GAP85192.1 - 4.3e-62 209.1 0.0 3.1e-61 206.3 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 GAP85192.1 - 0.00055 19.3 1.9 0.0014 18.0 1.3 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 Methyltransf_2 PF00891.13 GAP85193.1 - 5.1e-29 101.1 0.0 7.4e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase FAD_binding_4 PF01565.18 GAP85194.1 - 1.8e-27 95.4 0.2 4.2e-27 94.3 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain UbiA PF01040.13 GAP85195.1 - 8e-33 113.7 17.3 1e-32 113.3 12.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family adh_short PF00106.20 GAP85196.1 - 4.4e-16 59.2 0.1 1.2e-15 57.8 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAP85196.1 - 1.5e-07 31.2 0.0 3.1e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAP85196.1 - 0.057 12.8 0.0 0.1 12.0 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family OPT PF03169.10 GAP85197.1 - 0.0047 15.4 0.1 0.0054 15.2 0.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein p450 PF00067.17 GAP85198.1 - 1e-26 93.5 0.1 2.4e-22 79.1 0.1 3.2 2 1 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 GAP85200.1 - 1.1e-48 165.9 0.0 1.5e-48 165.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AAA PF00004.24 GAP85202.1 - 1.7e-17 63.8 0.0 3.6e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAP85202.1 - 0.00018 21.5 0.7 0.0012 18.9 0.1 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 GAP85202.1 - 0.00025 21.1 0.2 0.032 14.3 0.0 2.6 1 1 1 2 2 2 1 AAA domain Zot PF05707.7 GAP85202.1 - 0.00046 19.7 0.3 0.0086 15.5 0.1 2.4 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_5 PF07728.9 GAP85202.1 - 0.00089 19.0 0.0 0.0025 17.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 GAP85202.1 - 0.067 12.5 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAP85202.1 - 0.074 13.8 4.0 0.11 13.3 0.5 3.1 2 2 0 2 2 2 0 AAA domain AAA_19 PF13245.1 GAP85202.1 - 0.18 11.5 0.1 0.49 10.1 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain U79_P34 PF03064.11 GAP85202.1 - 1.8 8.0 19.4 3.8 6.9 13.4 1.6 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Ribosomal_60s PF00428.14 GAP85203.1 - 0.012 16.0 7.5 0.012 16.0 5.2 3.7 3 1 0 3 3 3 0 60s Acidic ribosomal protein HEAT_EZ PF13513.1 GAP85204.1 - 1.3e-20 73.2 11.2 1.3e-07 31.9 0.1 9.8 8 1 2 10 10 10 3 HEAT-like repeat HEAT_2 PF13646.1 GAP85204.1 - 1.3e-18 67.0 16.5 1.6e-09 37.9 0.1 8.9 4 3 5 10 10 9 5 HEAT repeats HEAT PF02985.17 GAP85204.1 - 6.9e-18 63.0 9.6 0.0037 17.2 0.0 9.9 9 0 0 9 9 9 4 HEAT repeat Vac14_Fab1_bd PF12755.2 GAP85204.1 - 1.9e-11 44.1 0.0 0.0046 17.3 0.1 6.1 4 1 3 7 7 6 2 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 GAP85204.1 - 5.6e-07 29.3 0.2 0.17 11.5 0.0 4.3 4 1 1 5 5 4 2 rRNA processing/ribosome biogenesis MMS19_C PF12460.3 GAP85204.1 - 2.8e-06 26.3 4.3 8.8e-06 24.7 0.1 3.6 3 2 2 5 5 5 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 GAP85204.1 - 3.6e-05 23.2 0.4 0.0033 16.7 0.0 3.9 3 1 1 4 4 4 1 CLASP N terminal TFCD_C PF12612.3 GAP85204.1 - 0.0012 18.3 0.2 0.61 9.4 0.0 4.0 3 1 1 4 4 4 1 Tubulin folding cofactor D C terminal Adaptin_N PF01602.15 GAP85204.1 - 0.0016 16.8 1.5 0.082 11.2 0.2 3.1 1 1 2 3 3 3 2 Adaptin N terminal region Proteasom_PSMB PF10508.4 GAP85204.1 - 0.0019 16.5 0.0 0.01 14.1 0.0 2.3 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit IBN_N PF03810.14 GAP85204.1 - 0.0039 17.0 0.2 0.036 13.9 0.0 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain CAS_CSE1 PF03378.10 GAP85204.1 - 0.024 12.9 0.7 1.9 6.6 0.0 3.0 3 0 0 3 3 3 0 CAS/CSE protein, C-terminus V-ATPase_H_N PF03224.9 GAP85204.1 - 0.036 13.1 0.4 0.2 10.7 0.0 2.4 3 0 0 3 3 3 0 V-ATPase subunit H DUF3535 PF12054.3 GAP85204.1 - 0.036 12.6 0.1 0.075 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) DRIM PF07539.7 GAP85204.1 - 0.043 13.2 0.4 0.17 11.2 0.3 2.0 1 0 0 1 1 1 0 Down-regulated in metastasis DNA_alkylation PF08713.6 GAP85204.1 - 0.05 13.1 0.5 0.44 10.0 0.0 2.7 3 0 0 3 3 3 0 DNA alkylation repair enzyme Telomere_reg-2 PF10193.4 GAP85204.1 - 0.12 12.6 2.0 0.25 11.6 0.4 2.3 2 0 0 2 2 1 0 Telomere length regulation protein Antimicrobial_4 PF08024.6 GAP85204.1 - 0.24 11.2 0.8 0.57 10.0 0.6 1.6 1 0 0 1 1 1 0 Ant antimicrobial peptide Arm PF00514.18 GAP85204.1 - 8 6.4 16.7 9.4 6.2 0.0 6.1 7 0 0 7 7 5 0 Armadillo/beta-catenin-like repeat Pyr_redox_2 PF07992.9 GAP85205.1 - 1.2e-18 67.7 3.0 1.9e-17 63.7 1.3 4.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAP85205.1 - 1.8e-12 47.4 1.7 6.6e-11 42.4 0.5 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP85205.1 - 1.3e-07 31.8 0.0 0.03 14.3 0.0 3.5 2 1 2 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAP85205.1 - 9.1e-05 21.5 0.0 0.0027 16.6 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 GAP85205.1 - 0.00025 20.0 4.9 0.49 9.2 0.0 3.7 3 1 1 4 4 4 2 FAD dependent oxidoreductase DUF4147 PF13660.1 GAP85205.1 - 0.00031 19.9 0.2 0.31 10.1 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4147) Trp_halogenase PF04820.9 GAP85205.1 - 0.00071 18.3 1.6 3.3 6.2 0.0 3.2 2 1 1 3 3 3 2 Tryptophan halogenase Lycopene_cycl PF05834.7 GAP85205.1 - 0.002 17.0 0.9 0.1 11.4 0.1 3.3 3 1 1 4 4 4 1 Lycopene cyclase protein GIDA PF01134.17 GAP85205.1 - 0.0043 15.9 2.6 0.24 10.1 0.1 2.8 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 GAP85205.1 - 0.0043 15.9 0.2 0.89 8.3 0.0 2.7 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 GAP85205.1 - 0.013 15.5 0.1 0.77 9.8 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAP85205.1 - 0.04 12.3 1.3 0.6 8.5 0.1 3.0 3 0 0 3 3 3 0 HI0933-like protein TrkA_N PF02254.13 GAP85205.1 - 0.078 12.9 0.1 7.4 6.6 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.1 GAP85205.1 - 0.16 11.7 2.0 87 2.8 0.0 4.3 4 1 1 5 5 5 0 FAD-NAD(P)-binding CBS PF00571.23 GAP85206.1 - 2.8e-18 65.4 5.1 9.5e-06 25.3 0.1 5.5 5 0 0 5 5 5 5 CBS domain Mog1 PF04603.7 GAP85207.1 - 1.3e-19 70.5 0.1 9.3e-19 67.7 0.1 1.9 1 1 0 1 1 1 1 Ran-interacting Mog1 protein SprT-like PF10263.4 GAP85208.1 - 1.9e-41 141.3 1.2 3e-41 140.7 0.2 1.8 2 0 0 2 2 2 1 SprT-like family Glucan_synthase PF02364.10 GAP85209.1 - 0 1435.2 0.0 0 1434.6 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 GAP85209.1 - 3.9e-38 129.9 0.1 1.3e-37 128.2 0.1 2.0 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Abhydrolase_6 PF12697.2 GAP85211.1 - 1.2e-14 54.7 12.5 3.3e-13 50.0 8.6 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP85211.1 - 2.4e-08 33.8 0.0 1.4e-07 31.3 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP85211.1 - 4.5e-06 26.3 0.6 8.8e-06 25.4 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold PBP1_TM PF14812.1 GAP85211.1 - 3.2 8.1 7.1 6.7 7.0 0.5 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RTA1 PF04479.8 GAP85212.1 - 1.7e-17 63.6 6.0 7e-17 61.6 4.1 1.8 1 1 0 1 1 1 1 RTA1 like protein TctB PF07331.6 GAP85212.1 - 0.1 12.2 7.0 2 8.0 0.4 2.8 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF3995 PF13160.1 GAP85212.1 - 0.35 10.9 7.5 0.32 11.0 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3995) DEAD PF00270.24 GAP85213.1 - 1.6e-44 151.3 0.0 2.4e-44 150.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP85213.1 - 1.8e-28 98.1 0.0 3.6e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAP85213.1 - 0.0011 18.8 0.0 0.0029 17.4 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Bystin PF05291.6 GAP85215.1 - 7.3e-111 369.9 0.0 1e-110 369.4 0.0 1.1 1 0 0 1 1 1 1 Bystin Rsa3 PF14615.1 GAP85216.1 - 3.1e-20 71.2 0.4 4.2e-20 70.7 0.2 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 Ytp1 PF10355.4 GAP85217.1 - 1.8e-109 365.1 5.6 1.8e-109 365.1 3.9 1.7 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 GAP85217.1 - 1.3e-32 111.4 4.7 1.3e-32 111.4 3.3 3.3 4 0 0 4 4 4 2 Domain of unknown function (DUF2427) Lactamase_B PF00753.22 GAP85218.1 - 2.4e-25 89.3 2.9 3.4e-25 88.8 2.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAP85218.1 - 8e-07 28.7 0.1 1.5e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAP85218.1 - 0.0064 16.2 0.1 0.0094 15.6 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DinB_2 PF12867.2 GAP85218.1 - 0.046 14.0 0.2 0.084 13.2 0.1 1.7 1 1 0 1 1 1 0 DinB superfamily UCH PF00443.24 GAP85219.1 - 1.2e-54 185.2 3.7 1.7e-54 184.7 2.6 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAP85219.1 - 1.4e-32 113.3 2.1 2.3e-32 112.6 1.5 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 GAP85219.1 - 0.00029 20.8 0.2 0.00029 20.8 0.2 2.6 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein TF_Zn_Ribbon PF08271.7 GAP85219.1 - 0.29 10.4 8.5 3.1 7.1 0.1 4.1 3 1 1 4 4 4 0 TFIIB zinc-binding zf-ribbon_3 PF13248.1 GAP85219.1 - 3.4 6.9 8.2 14 5.0 0.2 3.7 3 1 0 3 3 3 0 zinc-ribbon domain zf-CCHC PF00098.18 GAP85219.1 - 5.9 7.0 11.3 22 5.1 0.1 4.4 4 0 0 4 4 4 0 Zinc knuckle N6-adenineMlase PF10237.4 GAP85220.1 - 1.6e-49 167.7 0.0 2e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Myco_19_kDa PF05481.7 GAP85220.1 - 0.39 10.5 2.1 0.7 9.6 1.4 1.3 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen NAD_binding_10 PF13460.1 GAP85221.1 - 5.2e-19 68.9 0.0 7.5e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAP85221.1 - 7.3e-16 58.1 0.0 9.5e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 GAP85221.1 - 1.9e-13 50.4 0.1 3.7e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAP85221.1 - 8.2e-10 37.8 0.0 1.4e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 GAP85221.1 - 2.8e-09 36.3 0.0 4.5e-08 32.3 0.0 2.5 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 GAP85221.1 - 0.00039 20.3 0.0 0.0011 18.9 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 GAP85221.1 - 0.00074 18.5 0.2 0.035 13.0 0.1 2.7 1 1 1 2 2 2 1 Male sterility protein Saccharop_dh PF03435.13 GAP85221.1 - 0.0038 16.2 0.0 0.0058 15.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 GAP85221.1 - 0.013 15.1 0.0 0.24 11.0 0.0 2.3 2 0 0 2 2 2 0 KR domain DDE_Tnp_1_3 PF13612.1 GAP85221.1 - 0.11 12.2 0.0 0.47 10.1 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain Polysacc_synt_2 PF02719.10 GAP85221.1 - 0.11 11.3 0.0 0.21 10.4 0.0 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein PCI PF01399.22 GAP85222.1 - 0.11 12.8 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 PCI domain Gaa1 PF04114.9 GAP85223.1 - 3.1e-96 323.0 0.9 4.4e-96 322.5 0.6 1.3 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Rhomboid PF01694.17 GAP85224.1 - 4.3e-12 46.2 12.9 4.3e-12 46.2 8.9 1.6 2 0 0 2 2 2 1 Rhomboid family 5TM-5TMR_LYT PF07694.7 GAP85224.1 - 0.0051 16.1 4.7 0.0051 16.1 3.3 1.9 2 0 0 2 2 2 1 5TMR of 5TMR-LYT Aconitase PF00330.15 GAP85225.1 - 2.2e-173 577.0 0.0 3.7e-173 576.2 0.0 1.3 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 GAP85225.1 - 6.6e-45 152.4 0.0 1.2e-44 151.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.3 GAP85226.1 - 3.3e-09 36.6 0.1 5.9e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAP85226.1 - 0.0061 16.7 0.1 0.013 15.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 GAP85226.1 - 0.09 12.8 0.2 0.13 12.3 0.1 1.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DASH_Dam1 PF08653.5 GAP85227.1 - 4.9e-27 93.4 0.6 6.7e-27 93.0 0.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 rve PF00665.21 GAP85228.1 - 1.2e-09 38.3 0.0 2.9e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 GAP85228.1 - 1.6e-05 24.3 0.0 3.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2_4 PF13894.1 GAP85228.1 - 0.61 10.5 5.0 3.9 8.0 3.5 2.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 GAP85228.1 - 1 9.8 5.7 4.9 7.7 3.9 2.2 1 0 0 1 1 1 0 Zinc finger, C2H2 type CRAL_TRIO PF00650.15 GAP85229.1 - 1.4e-39 135.1 0.0 2.5e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAP85229.1 - 9.4e-14 51.2 0.1 3.6e-13 49.4 0.0 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 GAP85229.1 - 2.1e-09 37.4 0.0 3.6e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Menin PF05053.8 GAP85229.1 - 0.09 10.9 0.8 0.16 10.1 0.6 1.4 1 0 0 1 1 1 0 Menin TP53IP5 PF15331.1 GAP85229.1 - 0.16 11.9 4.5 1.5 8.6 0.2 2.4 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 HIT PF01230.18 GAP85230.1 - 1e-21 77.2 0.1 1.4e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 GAP85230.1 - 1.8e-11 44.2 0.0 2.4e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 GAP85230.1 - 1.2e-05 24.9 0.0 1.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Gelsolin PF00626.17 GAP85231.1 - 5.3e-34 115.7 0.1 1.5e-10 40.6 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat Aminotran_1_2 PF00155.16 GAP85232.1 - 6.3e-38 130.6 0.0 7.5e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3755 PF12579.3 GAP85232.1 - 0.0049 16.2 0.9 0.01 15.2 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3755) Cys_Met_Meta_PP PF01053.15 GAP85232.1 - 0.073 11.3 0.0 0.14 10.4 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Glyco_hydro_17 PF00332.13 GAP85233.1 - 3e-07 29.7 0.1 1.6e-06 27.4 0.0 2.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 17 Inp1 PF12634.2 GAP85234.1 - 5.7e-30 103.9 0.0 1.8e-29 102.3 0.0 1.9 2 0 0 2 2 2 1 Inheritance of peroxisomes protein 1 Beta_elim_lyase PF01212.16 GAP85236.1 - 5.7e-65 219.3 0.0 9.6e-65 218.5 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Trp_DMAT PF11991.3 GAP85236.1 - 2e-16 60.2 0.0 5.9e-15 55.3 0.0 2.2 1 1 0 1 1 1 1 Tryptophan dimethylallyltransferase AAA_19 PF13245.1 GAP85237.1 - 0.0006 19.5 0.0 0.0013 18.3 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Arch_ATPase PF01637.13 GAP85237.1 - 0.013 15.2 1.1 0.13 11.9 0.0 2.5 3 0 0 3 3 3 0 Archaeal ATPase AAA_23 PF13476.1 GAP85237.1 - 0.033 14.5 0.0 0.08 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 GAP85237.1 - 0.043 13.3 0.0 0.086 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain zf-CCHC_4 PF14392.1 GAP85238.1 - 9.1 6.0 40.4 0.13 11.9 1.1 6.0 5 1 1 6 6 6 0 Zinc knuckle NPV_P10 PF05531.7 GAP85239.1 - 0.0036 17.5 22.4 1.8 8.8 0.3 6.1 2 1 4 6 6 6 3 Nucleopolyhedrovirus P10 protein DASH_Duo1 PF08651.5 GAP85239.1 - 0.009 15.5 7.2 0.18 11.3 0.3 4.4 4 1 1 5 5 5 1 DASH complex subunit Duo1 Laminin_II PF06009.7 GAP85239.1 - 3 7.5 15.4 0.97 9.1 0.3 3.6 4 0 0 4 4 4 0 Laminin Domain II Toxin_52 PF15605.1 GAP85239.1 - 4.7 7.1 8.4 0.14 12.0 0.3 2.5 3 0 0 3 3 3 0 Putative toxin 52 Rho_Binding PF08912.6 GAP85239.1 - 7.6 6.9 15.9 30 5.0 3.5 4.4 3 1 1 4 4 4 0 Rho Binding DnaJ-X PF14308.1 GAP85241.1 - 4.1e-70 235.1 0.8 4.1e-70 235.1 0.6 1.9 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 GAP85241.1 - 5.6e-26 90.0 0.6 1.5e-25 88.6 0.4 1.8 1 0 0 1 1 1 1 DnaJ domain PAT1 PF09770.4 GAP85241.1 - 0.075 11.2 4.3 0.1 10.7 3.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S8 PF00082.17 GAP85242.1 - 7.9e-13 48.1 0.0 1.3e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Subtilase family WD40 PF00400.27 GAP85244.1 - 2.8e-69 226.7 24.0 1.6e-11 43.6 0.2 11.9 11 0 0 11 11 11 7 WD domain, G-beta repeat PD40 PF07676.7 GAP85244.1 - 0.00046 19.7 7.4 15 5.3 0.0 7.2 8 0 0 8 8 8 2 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 GAP85244.1 - 0.004 16.4 2.2 30 4.0 0.0 5.5 5 0 0 5 5 5 1 Proteasome subunit A N-terminal signature eIF2A PF08662.6 GAP85244.1 - 0.12 12.0 0.0 26 4.4 0.0 3.6 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A HNH_2 PF13391.1 GAP85245.1 - 2.7e-08 33.4 0.1 5.8e-08 32.3 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease RmlD_sub_bind PF04321.12 GAP85246.1 - 2.4e-15 56.2 0.0 5e-15 55.1 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 GAP85246.1 - 5.5e-12 45.6 0.0 1.3e-11 44.4 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAP85246.1 - 0.00062 18.7 0.0 0.0012 17.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 GAP85246.1 - 0.00086 19.2 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP85246.1 - 0.0067 16.1 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 GAP85246.1 - 0.06 12.0 0.1 0.12 11.0 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Aminotran_3 PF00202.16 GAP85247.1 - 3.4e-11 42.5 0.0 4.8e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 GAP85247.1 - 0.00088 18.3 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Tyrosinase PF00264.15 GAP85248.1 - 2.1e-57 194.8 0.8 4.4e-57 193.8 0.6 1.6 1 0 0 1 1 1 1 Common central domain of tyrosinase Gal-bind_lectin PF00337.17 GAP85248.1 - 0.048 12.9 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Galactoside-binding lectin AMP-binding PF00501.23 GAP85249.1 - 2.7e-71 240.1 0.0 3.4e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAP85249.1 - 0.00032 21.5 0.0 0.00069 20.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.13 GAP85250.1 - 1.9e-17 63.0 0.1 1.9e-17 63.0 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP85250.1 - 4.9e-08 32.7 7.0 8.8e-08 31.9 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NIF PF03031.13 GAP85251.1 - 9.3e-36 122.8 0.0 1.4e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Esterase_phd PF10503.4 GAP85252.1 - 2.8e-05 23.4 0.1 6.7e-05 22.2 0.1 1.7 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 GAP85252.1 - 0.00052 19.2 0.2 0.0016 17.7 0.1 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.15 GAP85252.1 - 0.0013 18.1 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 GAP85252.1 - 0.013 15.3 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3173 PF11372.3 GAP85253.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3173) RNase_PH PF01138.16 GAP85254.1 - 4.4e-31 107.9 0.0 8.4e-31 107.0 0.0 1.5 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 eIF-4B PF06273.6 GAP85254.1 - 1.7 7.3 6.7 2.3 6.8 4.6 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Thioredoxin PF00085.15 GAP85255.1 - 4e-33 113.2 0.1 5.6e-27 93.4 0.1 2.6 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.1 GAP85255.1 - 2.8e-07 30.5 0.0 0.00061 19.8 0.0 3.6 3 1 1 4 4 4 3 Thioredoxin-like Thioredoxin_2 PF13098.1 GAP85255.1 - 4.3e-07 30.1 6.0 5.1e-06 26.6 0.3 3.2 2 1 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.16 GAP85255.1 - 6.8e-05 22.5 0.3 0.0044 16.6 0.0 3.0 3 0 0 3 3 3 1 AhpC/TSA family Thioredoxin_7 PF13899.1 GAP85255.1 - 0.0007 19.5 0.0 0.0018 18.2 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.1 GAP85255.1 - 0.0092 15.7 0.1 0.12 12.2 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin domain HyaE PF07449.6 GAP85255.1 - 0.011 15.5 0.0 2.7 7.9 0.0 3.3 3 1 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.19 GAP85255.1 - 0.02 14.8 0.0 0.56 10.2 0.0 2.6 2 0 0 2 2 2 0 Glutaredoxin MIF PF01187.13 GAP85255.1 - 0.087 12.9 0.7 0.28 11.2 0.1 2.0 2 0 0 2 2 2 0 Macrophage migration inhibitory factor (MIF) DUF605 PF04652.11 GAP85256.1 - 6.6e-100 335.1 6.0 7.5e-100 334.9 4.2 1.0 1 0 0 1 1 1 1 Vta1 like adh_short PF00106.20 GAP85257.1 - 3.8e-29 101.7 10.5 4.1e-28 98.3 7.3 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP85257.1 - 1.9e-28 99.8 0.7 1.6e-27 96.8 0.5 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP85257.1 - 7.8e-16 58.2 3.4 7.8e-16 58.2 2.4 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 GAP85257.1 - 3.5e-06 26.6 0.0 5.3e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 GAP85257.1 - 0.0071 15.2 1.7 0.037 12.9 1.2 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain Glyco_trans_4_4 PF13579.1 GAP85257.1 - 0.11 12.6 6.2 0.5 10.4 0.4 2.3 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain CAP PF00188.21 GAP85258.1 - 0.00021 21.7 0.5 0.00028 21.3 0.4 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.21 GAP85259.1 - 4e-07 30.5 0.1 5.4e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Glyco_hydro_43 PF04616.9 GAP85260.1 - 4e-32 111.4 7.7 4.9e-32 111.1 5.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 TRI12 PF06609.8 GAP85261.1 - 6.3e-72 242.6 22.2 8.3e-72 242.2 15.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 GAP85261.1 - 6.4e-27 94.1 52.8 6.7e-26 90.8 33.9 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP85261.1 - 6.5e-10 38.1 7.7 6.5e-10 38.1 5.4 3.7 2 1 2 4 4 4 1 Sugar (and other) transporter SieB PF14163.1 GAP85261.1 - 1.5 8.3 4.7 1.7 8.1 0.5 2.8 2 0 0 2 2 2 0 Superinfection exclusion protein B ECH PF00378.15 GAP85262.1 - 1.4e-51 174.9 0.0 1.8e-51 174.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family AMP-binding PF00501.23 GAP85263.1 - 4.8e-39 133.9 0.2 6.1e-39 133.5 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme ABC_tran PF00005.22 GAP85264.1 - 4.3e-34 117.7 0.0 8.4e-34 116.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 GAP85264.1 - 1.1e-24 87.2 11.5 1.1e-24 87.2 8.0 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_21 PF13304.1 GAP85264.1 - 1.2e-05 25.4 0.1 0.003 17.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 GAP85264.1 - 4.1e-05 22.9 0.3 0.0026 17.0 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAP85264.1 - 0.00058 19.3 0.3 0.0018 17.7 0.2 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 GAP85264.1 - 0.0006 19.9 0.3 0.0034 17.5 0.2 2.0 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 GAP85264.1 - 0.017 15.0 0.3 0.1 12.5 0.2 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 GAP85264.1 - 0.029 14.3 0.7 0.084 12.8 0.4 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 GAP85264.1 - 0.058 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 GAP85264.1 - 0.064 12.4 0.5 0.15 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 GAP85264.1 - 0.09 12.2 0.7 0.34 10.3 0.1 2.2 2 1 1 3 3 3 0 AAA-like domain Rbsn PF11464.3 GAP85265.1 - 0.0041 16.6 0.0 0.0076 15.7 0.0 1.3 1 0 0 1 1 1 1 Rabenosyn Rab binding domain Ank_4 PF13637.1 GAP85266.1 - 6.9e-11 42.3 0.1 1.2e-10 41.5 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAP85266.1 - 1.5e-10 41.2 0.0 2.3e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAP85266.1 - 6.4e-09 35.7 0.9 3.1e-06 27.2 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 GAP85266.1 - 7.7e-09 34.9 0.4 0.0018 17.9 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 GAP85266.1 - 2e-07 30.5 0.0 0.008 16.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Mo25 PF08569.6 GAP85266.1 - 0.009 15.0 0.2 0.016 14.2 0.1 1.3 1 0 0 1 1 1 1 Mo25-like Shigella_OspC PF06128.6 GAP85266.1 - 0.18 11.2 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Shigella flexneri OspC protein Herpes_UL25 PF01499.11 GAP85266.1 - 0.21 9.8 0.5 0.29 9.4 0.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family bZIP_1 PF00170.16 GAP85266.1 - 0.63 10.0 11.9 1.4 8.8 8.2 1.5 1 1 0 1 1 1 0 bZIP transcription factor DUF1652 PF07865.6 GAP85268.1 - 0.04 13.5 0.1 0.089 12.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1652) Pkinase PF00069.20 GAP85269.1 - 7.6e-34 117.0 0.0 1e-33 116.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP85269.1 - 3.4e-17 62.3 0.0 5.3e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP85269.1 - 0.0014 17.6 0.0 0.0028 16.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Mito_fiss_reg PF05308.6 GAP85271.1 - 0.003 16.9 1.6 0.0039 16.5 1.1 1.3 1 0 0 1 1 1 1 Mitochondrial fission regulator CAP_N PF01213.14 GAP85271.1 - 0.23 10.6 4.1 0.3 10.3 2.9 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal GrpB PF04229.9 GAP85272.1 - 1.1e-46 158.5 0.0 1.7e-46 157.9 0.0 1.3 1 1 0 1 1 1 1 GrpB protein Amidase PF01425.16 GAP85274.1 - 3.6e-47 161.2 0.1 4.2e-47 160.9 0.1 1.1 1 0 0 1 1 1 1 Amidase Oxidored_FMN PF00724.15 GAP85275.1 - 6.1e-89 298.3 0.0 7.1e-89 298.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family NACHT PF05729.7 GAP85276.1 - 7.8e-09 35.4 0.0 2e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 GAP85276.1 - 2.1e-06 27.6 0.6 4.1 7.3 0.0 4.8 5 0 0 5 5 5 1 AAA domain WD40 PF00400.27 GAP85276.1 - 6.1e-06 25.9 0.0 1.7e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 WD domain, G-beta repeat AAA_16 PF13191.1 GAP85276.1 - 2.6e-05 24.3 0.0 0.0001 22.3 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAP85276.1 - 0.0005 20.2 0.1 0.0042 17.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 GAP85276.1 - 0.0015 17.4 0.0 0.0038 16.1 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain HTH_20 PF12840.2 GAP85276.1 - 0.0051 16.5 0.1 0.031 14.0 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain AAA_18 PF13238.1 GAP85276.1 - 0.02 15.2 0.0 0.055 13.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain HTH_5 PF01022.15 GAP85276.1 - 0.023 14.3 0.3 0.1 12.2 0.1 2.2 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Hemerythrin PF01814.18 GAP85276.1 - 0.026 14.6 0.3 5.3 7.2 0.0 3.3 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain RNA_helicase PF00910.17 GAP85276.1 - 0.04 14.0 0.0 0.13 12.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase TPR_MLP1_2 PF07926.7 GAP85276.1 - 0.041 13.6 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein FliD_N PF02465.13 GAP85276.1 - 0.044 14.1 0.1 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus APS_kinase PF01583.15 GAP85276.1 - 0.057 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.1 GAP85276.1 - 0.087 13.6 0.0 0.29 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain HTH_24 PF13412.1 GAP85276.1 - 0.092 12.1 0.8 0.35 10.3 0.2 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Fungal_trans_2 PF11951.3 GAP85277.1 - 1.7e-22 79.5 0.0 2.1e-16 59.5 0.0 2.6 1 1 0 2 2 2 2 Fungal specific transcription factor domain TPR_11 PF13414.1 GAP85278.1 - 3.4e-59 196.4 22.1 2.2e-17 62.4 0.4 6.4 6 0 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 GAP85278.1 - 1.3e-48 160.7 14.6 1.6e-06 27.4 0.1 10.1 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.12 GAP85278.1 - 9.1e-41 134.5 13.1 3.8e-07 29.5 0.1 10.0 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_14 PF13428.1 GAP85278.1 - 9e-23 78.7 2.3 0.0026 18.2 0.0 8.4 5 3 2 8 8 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 GAP85278.1 - 2.5e-20 72.5 5.5 9.2e-05 23.0 0.1 6.7 3 3 3 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.1 GAP85278.1 - 1.1e-18 66.8 6.8 9.7e-09 35.0 0.7 6.3 3 3 3 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAP85278.1 - 9.2e-18 62.6 10.5 0.0012 18.4 0.1 9.0 7 2 2 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAP85278.1 - 7.6e-15 53.4 3.0 0.024 14.3 0.0 8.3 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAP85278.1 - 2.8e-13 48.9 5.6 0.049 13.8 0.0 8.6 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 GAP85278.1 - 1e-12 47.7 0.0 0.0014 18.4 0.0 5.3 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAP85278.1 - 3.4e-12 46.5 6.6 0.045 14.1 0.0 6.2 5 2 1 7 7 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 GAP85278.1 - 1.6e-06 28.1 6.2 4.8 7.8 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 GAP85278.1 - 7.4e-05 22.8 8.6 0.012 15.7 1.0 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 GAP85278.1 - 0.01 15.0 0.6 9.9 5.4 0.0 4.0 4 0 0 4 4 4 0 SHNi-TPR TPR_10 PF13374.1 GAP85278.1 - 0.024 14.5 0.6 0.91 9.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat XPC-binding PF09280.6 GAP85278.1 - 4.4 6.8 9.1 2.5 7.6 1.4 3.5 3 0 0 3 3 3 0 XPC-binding domain RNA_pol_Rpc34 PF05158.7 GAP85279.1 - 3.9e-82 276.0 0.0 4.5e-82 275.8 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.7 GAP85279.1 - 0.00041 20.1 0.0 0.00079 19.2 0.0 1.4 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_36 PF13730.1 GAP85279.1 - 0.0068 16.5 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain GntR PF00392.16 GAP85279.1 - 0.018 14.4 1.0 0.13 11.7 0.1 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family RPA_C PF08784.6 GAP85279.1 - 0.037 14.4 0.0 0.87 10.0 0.0 2.8 3 0 0 3 3 3 0 Replication protein A C terminal TFIIE_alpha PF02002.12 GAP85279.1 - 0.052 13.0 1.4 0.066 12.7 0.1 1.8 2 0 0 2 2 2 0 TFIIE alpha subunit HTH_27 PF13463.1 GAP85279.1 - 0.077 13.3 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain TrmB PF01978.14 GAP85279.1 - 0.12 12.0 0.1 5.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.15 GAP85279.1 - 0.15 12.2 0.5 4.2 7.5 0.1 2.7 2 1 0 2 2 2 0 Transcriptional regulator Pro_isomerase PF00160.16 GAP85280.1 - 9.2e-44 149.3 0.1 1.1e-43 149.1 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ENTH PF01417.15 GAP85281.1 - 2.6e-46 156.5 0.1 3.9e-46 155.9 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 GAP85281.1 - 0.00027 19.7 0.0 0.00043 19.0 0.0 1.3 1 0 0 1 1 1 1 ANTH domain MARVEL PF01284.18 GAP85282.1 - 0.062 13.1 14.1 0.22 11.3 9.8 1.8 1 1 0 1 1 1 0 Membrane-associating domain Serglycin PF04360.7 GAP85282.1 - 0.22 11.2 0.1 0.22 11.2 0.1 2.6 2 1 0 2 2 2 0 Serglycin RAP1 PF07218.6 GAP85282.1 - 0.74 7.8 5.6 0.92 7.5 3.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Corona_nucleoca PF00937.13 GAP85282.1 - 3.4 6.5 10.1 6 5.7 7.0 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Glyco_hydro_12 PF01670.11 GAP85283.1 - 3.1e-17 62.7 0.6 6.2e-17 61.8 0.4 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 MutS_IV PF05190.13 GAP85284.1 - 0.22 11.7 0.8 0.52 10.5 0.6 1.5 1 0 0 1 1 1 0 MutS family domain IV UDG PF03167.14 GAP85286.1 - 1.5e-11 43.9 0.0 6e-10 38.7 0.0 2.1 2 0 0 2 2 2 2 Uracil DNA glycosylase superfamily UDPGP PF01704.13 GAP85288.1 - 2.3e-43 148.2 0.0 6.8e-42 143.4 0.0 2.1 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 GAP85288.1 - 0.039 14.0 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain FAR1 PF03101.10 GAP85289.1 - 0.039 14.4 0.0 0.087 13.3 0.0 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain Mpv17_PMP22 PF04117.7 GAP85290.1 - 1.3e-28 98.4 2.9 2.1e-28 97.7 2.0 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family PX PF00787.19 GAP85291.1 - 5e-19 68.1 0.0 8.5e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 PX domain 2-Hacid_dh_C PF02826.14 GAP85295.1 - 4.4e-42 143.2 0.0 1.9e-41 141.1 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAP85295.1 - 0.003 17.0 0.0 0.0049 16.3 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain dsrm PF00035.20 GAP85296.1 - 0.01 16.4 0.0 0.021 15.3 0.0 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif Cwf_Cwc_15 PF04889.7 GAP85296.1 - 0.014 15.1 17.7 0.022 14.4 12.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.6 GAP85296.1 - 0.093 12.5 9.7 0.17 11.6 6.7 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal FLO_LFY PF01698.11 GAP85296.1 - 0.22 10.3 3.5 0.35 9.6 2.4 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein FAM176 PF14851.1 GAP85296.1 - 0.44 10.2 6.8 1 9.0 4.7 1.6 1 0 0 1 1 1 0 FAM176 family Vfa1 PF08432.5 GAP85296.1 - 0.57 10.1 10.0 0.93 9.4 6.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SAPS PF04499.10 GAP85296.1 - 0.57 8.7 2.0 0.75 8.3 1.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Tom22 PF04281.8 GAP85296.1 - 0.98 8.9 11.2 1.7 8.1 7.7 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 CDC45 PF02724.9 GAP85296.1 - 1.1 7.2 10.9 1.5 6.7 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.7 GAP85296.1 - 1.3 7.3 20.4 0.058 11.7 10.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_phi PF04931.8 GAP85296.1 - 1.4 6.5 10.6 1.8 6.2 7.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.7 GAP85296.1 - 3.8 6.6 12.8 5.5 6.1 8.9 1.2 1 0 0 1 1 1 0 NOA36 protein BTV_NS2 PF04514.7 GAP85296.1 - 4.8 5.9 10.4 7.2 5.3 7.2 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 RRN3 PF05327.6 GAP85296.1 - 6.1 4.8 6.9 7.8 4.4 4.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CENP-B_dimeris PF09026.5 GAP85296.1 - 8.4 6.7 17.9 32 4.8 12.4 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain adh_short PF00106.20 GAP85297.1 - 4.3e-22 78.7 1.3 5.9e-22 78.3 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP85297.1 - 1.1e-10 41.5 0.7 3e-10 40.0 0.5 1.7 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 GAP85297.1 - 0.026 13.2 0.2 0.73 8.4 0.2 2.1 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ras PF00071.17 GAP85298.1 - 1.4e-42 144.8 0.0 2e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAP85298.1 - 1.1e-14 54.9 0.0 1.5e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAP85298.1 - 5.9e-11 41.9 0.0 2.2e-10 40.0 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAP85298.1 - 0.0011 18.1 0.0 0.0014 17.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAP85298.1 - 0.0021 17.9 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAP85298.1 - 0.0026 17.2 0.0 0.0085 15.5 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 GAP85298.1 - 0.0032 17.3 0.0 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAP85298.1 - 0.01 15.9 0.0 0.019 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 GAP85298.1 - 0.016 14.4 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 GAP85298.1 - 0.017 14.6 0.0 0.17 11.3 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 GAP85298.1 - 0.024 14.6 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 GAP85298.1 - 0.035 13.2 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 GAP85298.1 - 0.043 13.4 0.0 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 GAP85298.1 - 0.047 13.6 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 GAP85298.1 - 0.12 12.1 0.0 0.4 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 GAP85298.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Glyco_hydro_2_N PF02837.13 GAP85299.1 - 5e-11 42.4 0.1 1.4e-10 40.9 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 GAP85299.1 - 1.3e-08 35.2 0.0 4.1e-08 33.6 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 GAP85299.1 - 6e-05 22.0 0.4 0.0001 21.3 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain ADH_N PF08240.7 GAP85300.1 - 7.3e-29 99.7 1.2 9.3e-29 99.3 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAP85300.1 - 6.3e-24 83.9 0.6 6.3e-24 83.9 0.4 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAP85300.1 - 2.4e-06 28.4 0.8 5.2e-06 27.3 0.2 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 GAP85300.1 - 0.0019 18.7 0.0 0.0043 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Pyr_redox PF00070.22 GAP85300.1 - 0.0096 16.3 0.2 0.09 13.1 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 GAP85300.1 - 0.015 14.6 0.2 0.029 13.7 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 GAP85300.1 - 0.036 12.5 1.8 0.051 12.0 1.2 1.2 1 0 0 1 1 1 0 HI0933-like protein AdoHcyase_NAD PF00670.16 GAP85300.1 - 0.13 12.1 1.0 0.26 11.1 0.7 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FAD_oxidored PF12831.2 GAP85300.1 - 2.8 6.9 6.5 4.5 6.2 4.5 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GST_N_3 PF13417.1 GAP85301.1 - 6.5e-14 51.9 0.0 1.8e-13 50.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAP85301.1 - 1.2e-10 41.2 0.0 3.1e-10 39.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAP85301.1 - 0.00018 21.5 0.0 0.00033 20.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAP85301.1 - 0.0005 19.9 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAP85301.1 - 0.00067 19.4 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAP85301.1 - 0.0015 18.9 0.0 0.0029 18.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Hist_deacetyl PF00850.14 GAP85302.1 - 2.1e-79 267.0 0.0 4.2e-79 266.0 0.0 1.5 1 0 0 1 1 1 1 Histone deacetylase domain Ribosomal_L14 PF00238.14 GAP85303.1 - 5.3e-33 113.3 0.0 6e-33 113.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF2413 PF10310.4 GAP85305.1 - 8.8e-144 479.6 0.0 1e-143 479.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Flu_M1_C PF08289.6 GAP85305.1 - 0.028 14.4 0.2 0.076 13.0 0.1 1.7 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain Malic_M PF03949.10 GAP85306.1 - 8.5e-75 251.5 0.0 1.2e-74 251.1 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 GAP85306.1 - 2e-66 223.0 0.0 3.7e-66 222.1 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain AlaDh_PNT_C PF01262.16 GAP85306.1 - 0.11 12.0 0.2 0.22 11.1 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1996 PF09362.5 GAP85307.1 - 2e-90 302.6 2.7 2.5e-90 302.2 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF1660 PF07874.6 GAP85307.1 - 0.03 14.5 1.2 9.2 6.6 0.0 2.8 3 0 0 3 3 3 0 Prophage protein (DUF1660) Syndecan PF01034.15 GAP85309.1 - 0.0046 16.5 0.3 0.011 15.3 0.2 1.6 1 0 0 1 1 1 1 Syndecan domain Rifin_STEVOR PF02009.11 GAP85309.1 - 0.11 12.1 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 Rifin/stevor family PhrC_PhrF PF11131.3 GAP85309.1 - 0.51 9.9 2.3 1.4 8.5 1.6 1.8 1 0 0 1 1 1 0 Rap-phr extracellular signalling SKG6 PF08693.5 GAP85309.1 - 1.8 7.9 6.3 5.9 6.2 4.4 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF1399 PF07173.7 GAP85310.1 - 1.1e-23 84.0 0.2 1.8e-15 57.4 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) Atg14 PF10186.4 GAP85312.1 - 3e-19 69.0 0.0 3e-19 69.0 0.0 1.9 2 0 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 Apq12 PF12716.2 GAP85313.1 - 0.15 11.7 1.2 0.26 10.9 0.8 1.4 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis Kinesin PF00225.18 GAP85315.1 - 5.8e-114 380.2 0.0 8.2e-114 379.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Herpes_UL14 PF03580.9 GAP85315.1 - 0.013 15.2 2.9 0.027 14.2 2.0 1.5 1 0 0 1 1 1 0 Herpesvirus UL14-like protein Lactamase_B_2 PF12706.2 GAP85316.1 - 0.1 12.0 0.0 0.25 10.8 0.0 1.7 1 0 0 1 1 1 0 Beta-lactamase superfamily domain ELL PF10390.4 GAP85317.1 - 0.055 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL Toxin_58 PF15536.1 GAP85321.1 - 0.11 12.2 0.0 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Putative toxin 58 Nbas_N PF15492.1 GAP85322.1 - 0.043 12.9 0.1 5.6 5.9 0.0 2.9 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal RCC1_2 PF13540.1 GAP85322.1 - 0.42 10.2 0.0 0.42 10.2 0.0 3.4 5 0 0 5 5 5 0 Regulator of chromosome condensation (RCC1) repeat GFA PF04828.9 GAP85324.1 - 1.8e-14 53.4 4.1 2.7e-14 52.8 2.9 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme LMBR1 PF04791.11 GAP85325.1 - 1.5e-16 60.1 12.6 6.5e-15 54.6 1.8 2.3 1 1 1 2 2 2 2 LMBR1-like membrane protein DUF1980 PF09323.5 GAP85325.1 - 0.11 12.1 5.1 6.8 6.3 1.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Fungal_trans PF04082.13 GAP85326.1 - 9.5e-31 106.6 1.9 1.6e-30 105.8 1.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ldh_2 PF02615.9 GAP85327.1 - 4.5e-100 334.6 0.0 5.2e-100 334.4 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase ILVD_EDD PF00920.16 GAP85328.1 - 2.6e-155 517.8 4.2 3.1e-155 517.5 2.9 1.1 1 0 0 1 1 1 1 Dehydratase family Dabb PF07876.7 GAP85328.1 - 7.1e-12 45.6 0.1 1.3e-11 44.7 0.1 1.4 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Metallophos PF00149.23 GAP85329.1 - 5e-39 133.7 0.2 6.5e-39 133.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SUR7 PF06687.7 GAP85330.1 - 5e-34 117.7 9.9 8.4e-34 116.9 6.9 1.4 1 0 0 1 1 1 1 SUR7/PalI family WD40 PF00400.27 GAP85330.1 - 5.5e-22 76.7 8.5 3.6e-09 36.1 0.5 9.6 10 0 0 10 10 10 5 WD domain, G-beta repeat SR-25 PF10500.4 GAP85331.1 - 0.0046 16.4 8.7 0.0058 16.1 6.0 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 GAP85331.1 - 0.091 12.8 8.8 0.13 12.3 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) FancD2 PF14631.1 GAP85331.1 - 0.11 9.6 1.5 0.12 9.4 1.0 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Pyocin_S PF06958.7 GAP85331.1 - 1.5 9.1 4.3 5.2 7.4 3.0 1.8 1 1 0 1 1 1 0 S-type Pyocin Macoilin PF09726.4 GAP85331.1 - 2.4 6.3 5.4 2.3 6.3 3.7 1.0 1 0 0 1 1 1 0 Transmembrane protein RAP1 PF07218.6 GAP85331.1 - 5.3 5.0 5.6 5.5 4.9 3.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SOG2 PF10428.4 GAP85331.1 - 5.9 5.4 8.7 6.6 5.2 6.0 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein RRF PF01765.14 GAP85332.1 - 1.4e-12 47.3 0.2 1.9e-12 46.9 0.1 1.0 1 0 0 1 1 1 1 Ribosome recycling factor Frigida PF07899.6 GAP85332.1 - 0.0045 15.8 0.5 0.0078 15.0 0.4 1.3 1 0 0 1 1 1 1 Frigida-like protein Gp37 PF09646.5 GAP85333.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Gp37 protein Aldedh PF00171.17 GAP85334.1 - 6.4e-166 552.2 0.5 7.2e-166 552.0 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cys_Met_Meta_PP PF01053.15 GAP85334.1 - 0.13 10.4 0.0 0.21 9.8 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme SUR7 PF06687.7 GAP85336.1 - 0.17 11.4 6.1 0.021 14.3 0.8 1.8 2 0 0 2 2 2 0 SUR7/PalI family Tic20 PF09685.5 GAP85336.1 - 3.2 7.7 10.8 21 5.1 0.0 2.9 3 0 0 3 3 3 0 Tic20-like protein HATPase_c PF02518.21 GAP85337.1 - 3.8e-23 81.3 0.1 9.1e-23 80.1 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAP85337.1 - 3e-21 75.5 0.1 6.8e-21 74.3 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 GAP85337.1 - 3.3e-12 46.6 0.4 1.2e-07 32.0 0.0 3.4 4 0 0 4 4 3 2 PAS domain PAS_4 PF08448.5 GAP85337.1 - 1.6e-10 40.9 0.0 0.0003 20.7 0.0 3.7 3 0 0 3 3 3 2 PAS fold GAF_2 PF13185.1 GAP85337.1 - 1.4e-07 32.0 0.0 0.0013 19.2 0.0 2.7 2 0 0 2 2 2 2 GAF domain HisKA PF00512.20 GAP85337.1 - 3e-07 30.3 2.1 5.5e-07 29.4 0.0 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 GAP85337.1 - 9.5e-06 25.3 0.1 0.011 15.4 0.0 3.6 3 0 0 3 3 3 2 PAS fold PAS_3 PF08447.6 GAP85337.1 - 0.0034 17.4 0.8 0.0073 16.3 0.1 1.9 2 0 0 2 2 1 1 PAS fold GAF_3 PF13492.1 GAP85337.1 - 0.004 17.2 0.0 0.016 15.2 0.0 2.0 2 0 0 2 2 2 1 GAF domain PAS_8 PF13188.1 GAP85337.1 - 0.013 15.3 0.0 0.12 12.3 0.0 2.5 3 0 0 3 3 2 0 PAS domain CENP-Q PF13094.1 GAP85337.1 - 0.36 10.8 3.6 0.86 9.6 2.5 1.6 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Fungal_trans PF04082.13 GAP85338.1 - 1.1e-17 63.8 0.0 2.4e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP85338.1 - 4.6e-09 36.0 11.0 7.9e-09 35.2 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.16 GAP85339.1 - 1.3e-09 37.8 0.0 4.7e-09 36.0 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAP85339.1 - 9e-05 22.5 0.0 0.00018 21.5 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAP85339.1 - 0.00043 19.2 0.0 0.004 16.1 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.8 GAP85339.1 - 0.0019 17.4 0.0 0.0033 16.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family F420_oxidored PF03807.12 GAP85339.1 - 0.013 15.9 0.0 0.05 14.0 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 GAP85339.1 - 0.022 13.4 0.0 0.086 11.5 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family AP_endonuc_2 PF01261.19 GAP85339.1 - 0.05 12.8 0.0 0.098 11.9 0.0 1.7 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Serglycin PF04360.7 GAP85340.1 - 0.00051 19.7 8.5 0.036 13.7 3.2 2.7 2 0 0 2 2 2 2 Serglycin RXT2_N PF08595.6 GAP85340.1 - 0.26 11.0 1.1 0.51 10.1 0.8 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal MARVEL PF01284.18 GAP85341.1 - 1.2e-08 34.9 23.4 4.1e-08 33.1 15.5 2.1 1 1 1 2 2 2 1 Membrane-associating domain Methyltransf_2 PF00891.13 GAP85342.1 - 1e-36 126.3 0.1 1.6e-36 125.7 0.1 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 GAP85342.1 - 0.0024 17.4 0.0 0.0053 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP85342.1 - 0.0039 17.6 0.0 0.0098 16.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP85342.1 - 0.004 17.7 0.1 0.024 15.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain CheR PF01739.13 GAP85342.1 - 0.018 14.3 0.0 0.044 13.0 0.0 1.5 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain HTH_AsnC-type PF13404.1 GAP85342.1 - 0.062 12.8 0.0 0.21 11.1 0.0 1.9 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain TolB_N PF04052.8 GAP85342.1 - 0.092 12.8 0.0 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 TolB amino-terminal domain YkuI_C PF10388.4 GAP85342.1 - 0.098 12.3 0.2 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 EAL-domain associated signalling protein domain HTH_24 PF13412.1 GAP85342.1 - 0.16 11.3 0.1 0.48 9.8 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding GIT_SHD PF08518.6 GAP85343.1 - 3.4e-21 74.2 5.0 1.8e-12 46.3 2.2 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT DUF1843 PF08898.5 GAP85343.1 - 0.03 14.3 0.1 0.03 14.3 0.1 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) Ssu72 PF04722.8 GAP85344.1 - 1.9e-85 285.1 0.0 2.2e-85 284.9 0.0 1.1 1 0 0 1 1 1 1 Ssu72-like protein SH3_1 PF00018.23 GAP85345.1 - 3.5e-09 35.9 0.0 6.1e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAP85345.1 - 4e-09 35.9 0.1 7.8e-09 34.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAP85345.1 - 9.6e-05 21.8 0.0 0.00017 20.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Glyco_transf_28 PF03033.15 GAP85346.1 - 5.4e-20 71.5 0.3 1.3e-18 67.1 0.2 2.5 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 GAP85346.1 - 2.8e-05 22.8 0.0 6.3e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 GAP85346.1 - 0.014 15.0 0.3 0.037 13.6 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.6 GAP85346.1 - 0.037 14.1 0.0 0.099 12.8 0.0 1.8 1 0 0 1 1 1 0 ATG C terminal domain UIM PF02809.15 GAP85346.1 - 1.7 8.4 25.5 0.72 9.5 0.1 5.7 6 0 0 6 6 6 0 Ubiquitin interaction motif HSP70 PF00012.15 GAP85347.1 - 4e-229 761.5 6.7 4.5e-229 761.3 4.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAP85347.1 - 5.9e-15 54.6 0.1 1.2e-13 50.3 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 GAP85347.1 - 0.00059 19.6 3.1 0.34 10.7 0.6 3.6 2 1 0 2 2 2 2 Cell division protein FtsA FGGY_C PF02782.11 GAP85347.1 - 0.00099 18.7 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 GAP85347.1 - 0.038 13.2 0.1 8.5 5.5 0.0 2.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Bromodomain PF00439.20 GAP85348.1 - 1.3e-31 108.3 0.3 4.3e-15 55.3 0.1 2.4 2 0 0 2 2 2 2 Bromodomain Daxx PF03344.10 GAP85348.1 - 0.0059 15.1 20.1 0.012 14.2 13.9 1.4 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 GAP85348.1 - 0.024 12.6 23.4 0.012 13.6 14.6 1.6 2 0 0 2 2 2 0 Nop14-like family BUD22 PF09073.5 GAP85348.1 - 3.8 6.4 19.7 6.1 5.8 13.7 1.3 1 0 0 1 1 1 0 BUD22 Spore_coat_CotO PF14153.1 GAP85348.1 - 4.3 6.7 6.9 8.2 5.8 4.8 1.5 1 0 0 1 1 1 0 Spore coat protein CotO CDC45 PF02724.9 GAP85348.1 - 4.9 5.0 19.5 7.4 4.4 13.5 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.6 GAP85348.1 - 5.1 6.5 17.3 11 5.4 12.0 1.5 1 0 0 1 1 1 0 PPP4R2 DUF2890 PF11081.3 GAP85348.1 - 6.8 6.7 14.6 20 5.1 10.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CKS PF01111.14 GAP85349.1 - 3.2e-36 122.9 1.1 3.9e-36 122.7 0.7 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit ERO1 PF04137.10 GAP85350.1 - 1.3e-137 458.6 0.1 1.9e-137 458.0 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) HVSL PF09749.4 GAP85351.1 - 9.3e-55 185.2 0.0 5.6e-54 182.6 0.0 2.1 1 1 0 1 1 1 1 Uncharacterised conserved protein Pal1 PF08316.6 GAP85352.1 - 9e-08 32.6 0.1 1.1e-07 32.3 0.0 1.2 1 0 0 1 1 1 1 Pal1 cell morphology protein CPSF_A PF03178.10 GAP85354.1 - 3.4e-77 259.6 0.0 6.7e-77 258.7 0.0 1.5 1 0 0 1 1 1 1 CPSF A subunit region DUF2638 PF10937.3 GAP85356.1 - 0.11 13.5 0.5 0.12 13.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2638) RNA_pol_Rpb1_1 PF04997.7 GAP85358.1 - 5e-111 371.1 0.1 7.9e-111 370.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 GAP85358.1 - 2e-101 338.9 0.0 3.1e-101 338.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 GAP85358.1 - 1.9e-70 236.0 0.0 3.8e-70 235.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 GAP85358.1 - 2e-49 167.8 1.1 3.5e-49 167.1 0.7 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 GAP85358.1 - 1.9e-44 151.2 0.0 4.8e-44 149.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 GAP85358.1 - 7.2e-38 129.3 3.4 3.6e-37 127.1 2.4 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 GAP85358.1 - 4.7e-36 122.7 0.0 1.1e-35 121.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 GAP85358.1 - 0.0027 17.6 202.2 0.068 13.3 6.8 14.0 8 3 2 14 14 14 10 RNA polymerase Rpb1 C-terminal repeat WD40 PF00400.27 GAP85359.1 - 2.9e-13 49.1 5.2 6.2e-05 22.7 0.1 5.5 6 0 0 6 6 6 2 WD domain, G-beta repeat eIF2A PF08662.6 GAP85359.1 - 3e-06 27.0 0.1 0.021 14.5 0.0 3.3 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 GAP85359.1 - 0.00033 20.1 0.7 0.0054 16.2 0.0 2.6 2 2 1 3 3 3 1 PQQ-like domain Thg1C PF14413.1 GAP85360.1 - 1.4e-51 173.2 0.6 1.9e-51 172.8 0.4 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 GAP85360.1 - 6.1e-47 158.6 0.0 8.7e-47 158.1 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase G-patch PF01585.18 GAP85361.1 - 0.0071 16.1 0.1 0.035 13.8 0.1 2.1 1 1 0 1 1 1 1 G-patch domain CAF-1_p150 PF11600.3 GAP85361.1 - 0.2 10.9 36.8 0.23 10.8 25.5 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RR_TM4-6 PF06459.7 GAP85361.1 - 1.8 8.3 12.8 2.4 7.9 8.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pilt PF15453.1 GAP85361.1 - 1.9 8.1 12.0 2.2 7.8 8.3 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Spore_coat_CotO PF14153.1 GAP85361.1 - 7.8 5.8 17.8 11 5.4 12.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO APC_CDC26 PF10471.4 GAP85362.1 - 1.2e-12 48.4 10.6 1.2e-12 48.4 7.3 4.9 4 2 1 5 5 5 1 Anaphase-promoting complex APC subunit 1 CENP-B_dimeris PF09026.5 GAP85362.1 - 0.0017 18.5 7.3 0.0017 18.5 5.1 3.4 3 0 0 3 3 3 1 Centromere protein B dimerisation domain Spt5_N PF11942.3 GAP85362.1 - 0.015 15.9 7.8 0.015 15.9 5.4 4.4 4 0 0 4 4 4 0 Spt5 transcription elongation factor, acidic N-terminal Nop14 PF04147.7 GAP85362.1 - 0.05 11.5 24.1 0.091 10.6 10.4 2.2 2 0 0 2 2 2 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.3 GAP85362.1 - 1.5 8.6 34.7 0.14 12.0 2.4 3.3 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 Nucleoplasmin PF03066.10 GAP85362.1 - 2.4 7.6 28.4 0.042 13.3 6.5 2.8 3 0 0 3 3 3 0 Nucleoplasmin NOA36 PF06524.7 GAP85362.1 - 5.1 6.2 20.0 0.73 9.0 6.4 2.5 2 0 0 2 2 2 0 NOA36 protein Peptidase_M1 PF01433.15 GAP85363.1 - 2.3e-08 33.5 0.0 0.0017 17.5 0.0 3.2 3 0 0 3 3 3 3 Peptidase family M1 APG6 PF04111.7 GAP85363.1 - 0.097 11.7 1.2 0.21 10.6 0.8 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 SAS4 PF15460.1 GAP85364.1 - 3.4e-34 116.7 0.3 1.3e-33 114.8 0.2 2.1 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 PPP4R2 PF09184.6 GAP85364.1 - 0.14 11.6 12.7 0.3 10.5 8.8 1.5 1 0 0 1 1 1 0 PPP4R2 Daxx PF03344.10 GAP85364.1 - 0.22 9.9 24.4 0.031 12.7 13.6 1.9 2 0 0 2 2 2 0 Daxx Family Nop14 PF04147.7 GAP85364.1 - 0.45 8.3 23.9 0.77 7.5 16.6 1.3 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 GAP85364.1 - 0.51 9.0 34.6 0.023 13.4 16.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) CobT PF06213.7 GAP85364.1 - 8.4 5.4 23.9 16 4.4 16.6 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RRN3 PF05327.6 GAP85364.1 - 8.5 4.3 8.2 13 3.7 5.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 IQ PF00612.22 GAP85365.1 - 3.6e-05 23.0 1.4 0.00014 21.2 1.0 2.1 1 0 0 1 1 1 1 IQ calmodulin-binding motif Cellulase PF00150.13 GAP85366.1 - 1.6e-19 70.1 0.0 2.3e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 GAP85366.1 - 2.9e-14 52.4 9.6 1.2e-13 50.4 6.7 2.2 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF4038 PF13204.1 GAP85366.1 - 0.0024 17.2 0.3 0.0097 15.2 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF4038) Glyco_hydro_42 PF02449.10 GAP85366.1 - 0.0047 16.0 0.0 0.02 14.0 0.0 1.8 2 0 0 2 2 2 1 Beta-galactosidase Cellulase-like PF12876.2 GAP85366.1 - 0.019 15.4 0.0 0.044 14.2 0.0 1.7 1 1 0 1 1 1 0 Sugar-binding cellulase-like Glyco_hydro_2_C PF02836.12 GAP85366.1 - 0.028 13.3 0.0 0.056 12.3 0.0 1.6 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain MGC-24 PF05283.6 GAP85366.1 - 0.69 9.6 16.7 0.16 11.7 8.4 2.0 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) ABC_membrane_2 PF06472.10 GAP85367.1 - 3.1e-97 325.0 2.6 2.6e-96 322.0 0.0 2.6 3 0 0 3 3 3 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 GAP85367.1 - 9.3e-17 61.6 0.0 2.3e-16 60.3 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_17 PF13207.1 GAP85367.1 - 0.016 16.0 0.0 0.066 14.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 GAP85367.1 - 0.016 15.1 0.0 0.041 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activ_2 PF14532.1 GAP85367.1 - 0.029 14.4 0.0 0.073 13.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.24 GAP85367.1 - 0.03 14.5 0.2 0.3 11.2 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.1 GAP85367.1 - 0.035 14.0 0.0 0.1 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 GAP85367.1 - 0.043 13.3 0.0 0.098 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.16 GAP85367.1 - 0.052 12.6 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 GAP85367.1 - 0.068 13.4 7.0 0.97 9.7 4.9 2.4 1 1 0 1 1 1 0 AAA domain End3 PF12761.2 GAP85367.1 - 0.24 11.0 2.3 0.44 10.1 1.6 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 NIF PF03031.13 GAP85368.1 - 1.7e-51 174.0 0.2 2.4e-51 173.5 0.2 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF1713 PF08213.6 GAP85369.1 - 3e-12 45.9 21.1 3e-12 45.9 14.6 2.1 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.5 GAP85369.1 - 0.083 12.8 0.7 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial protein Pet20 Arginase PF00491.16 GAP85370.1 - 2.9e-72 243.3 0.3 3.7e-72 242.9 0.2 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 GAP85370.1 - 0.18 12.0 0.4 0.28 11.3 0.3 1.3 1 0 0 1 1 1 0 UPF0489 domain Fungal_trans PF04082.13 GAP85371.1 - 1.3e-15 56.9 0.1 1.9e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP85371.1 - 2.2e-05 24.2 7.6 2.2e-05 24.2 5.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 GAP85372.1 - 7.4e-26 90.6 40.6 1.3e-21 76.7 14.4 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP85372.1 - 3.7e-05 22.4 0.9 3.7e-05 22.4 0.7 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter ATG22 PF11700.3 GAP85372.1 - 0.0013 17.3 24.0 0.011 14.2 7.4 2.5 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like OATP PF03137.15 GAP85372.1 - 0.021 12.9 0.0 0.058 11.4 0.0 1.7 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SET PF00856.23 GAP85375.1 - 6.9e-06 26.4 0.1 3e-05 24.3 0.1 2.0 1 1 0 1 1 1 1 SET domain Peptidase_M16 PF00675.15 GAP85376.1 - 1.1e-55 187.4 0.2 5e-55 185.3 0.1 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 GAP85376.1 - 1.6e-37 129.0 0.1 9.7e-37 126.4 0.0 2.2 3 0 0 3 3 3 1 Peptidase M16 inactive domain Esterase PF00756.15 GAP85376.1 - 0.049 13.0 0.1 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Raffinose_syn PF05691.7 GAP85377.1 - 5.5e-54 182.9 1.9 3.4e-48 163.7 1.4 3.2 2 1 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 GAP85377.1 - 2.5e-05 23.1 0.3 3.9e-05 22.5 0.2 1.2 1 0 0 1 1 1 1 Melibiase Abhydrolase_5 PF12695.2 GAP85378.1 - 1.2e-09 38.0 0.0 1.7e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP85378.1 - 5.5e-07 29.6 0.0 2.1e-06 27.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 GAP85378.1 - 0.03 13.5 0.1 1.3 8.2 0.0 2.3 2 1 0 2 2 2 0 Secretory lipase Peptidase_S9 PF00326.16 GAP85378.1 - 0.053 12.7 0.0 0.078 12.1 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 GAP85378.1 - 0.11 11.9 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF4121 PF13497.1 GAP85379.1 - 0.047 12.6 0.0 0.068 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) LRR_4 PF12799.2 GAP85382.1 - 8.9e-40 133.7 48.5 1.4e-12 46.9 1.2 8.1 3 2 6 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAP85382.1 - 2.1e-19 69.0 30.3 5.4e-08 32.4 3.3 5.0 2 2 2 5 5 5 5 Leucine rich repeat LRR_1 PF00560.28 GAP85382.1 - 1.6e-11 42.5 33.2 0.52 10.5 0.1 11.5 12 0 0 12 12 12 7 Leucine Rich Repeat LRR_7 PF13504.1 GAP85382.1 - 8.1e-11 40.2 17.3 4.4 7.9 0.0 10.3 9 1 1 10 10 10 4 Leucine rich repeat LRR_6 PF13516.1 GAP85382.1 - 8.6e-11 40.7 22.5 0.45 10.7 0.1 10.4 9 2 2 11 11 11 3 Leucine Rich repeat LRR_9 PF14580.1 GAP85382.1 - 1.8e-09 37.3 12.9 0.00011 21.8 1.4 3.8 1 1 2 3 3 3 3 Leucine-rich repeat Aldo_ket_red PF00248.16 GAP85383.1 - 8e-35 120.0 0.0 1.1e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 GAP85384.1 - 7.6e-05 21.6 0.1 8.9e-05 21.4 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.20 GAP85385.1 - 6.2e-09 35.3 0.0 8.1e-08 31.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP85385.1 - 1.6e-07 30.6 0.0 1.9e-06 27.1 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Cellulase PF00150.13 GAP85386.1 - 4.8e-16 58.7 1.8 7e-16 58.2 1.3 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF3377 PF11857.3 GAP85387.1 - 0.0045 16.5 0.7 0.043 13.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3377) DUF3367 PF11847.3 GAP85387.1 - 0.017 13.1 0.7 0.025 12.5 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) Cation_ATPase_C PF00689.16 GAP85387.1 - 0.41 10.1 12.1 1.1 8.7 0.8 2.4 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus CoxIIa PF08113.6 GAP85387.1 - 8.5 6.1 8.3 2.9 7.6 0.5 3.2 3 1 0 3 3 3 0 Cytochrome c oxidase subunit IIa family Acyl_transf_1 PF00698.16 GAP85388.1 - 1.5e-60 205.2 0.0 2.4e-60 204.5 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 GAP85388.1 - 1.4e-54 184.5 0.5 3.7e-54 183.1 0.4 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 GAP85388.1 - 2.5e-52 177.8 0.0 4.6e-52 177.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.21 GAP85388.1 - 6.1e-46 156.9 0.0 2.5e-45 154.9 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short PF00106.20 GAP85388.1 - 1.2e-41 142.4 0.3 1.2e-41 142.4 0.2 2.2 2 0 0 2 2 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAP85388.1 - 3.2e-34 117.3 0.0 1.3e-33 115.3 0.0 2.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain MFS_1 PF07690.11 GAP85388.1 - 4e-24 84.9 35.6 6.6e-24 84.2 24.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily ADH_zinc_N PF00107.21 GAP85388.1 - 1.3e-17 63.5 0.0 3.7e-17 62.1 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sugar_tr PF00083.19 GAP85388.1 - 1.4e-10 40.3 12.6 3e-10 39.2 8.7 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter ADH_N PF08240.7 GAP85388.1 - 3e-09 36.6 0.2 1.3e-08 34.5 0.2 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 GAP85388.1 - 4.8e-08 33.1 0.1 2.2e-07 31.0 0.1 2.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 GAP85388.1 - 3e-05 23.7 0.0 9.2e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 GAP85388.1 - 4.2e-05 24.4 0.0 0.00025 21.9 0.0 2.4 2 0 0 2 2 1 1 Zinc-binding dehydrogenase 3Beta_HSD PF01073.14 GAP85388.1 - 0.0003 19.5 0.1 0.00057 18.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_31 PF13847.1 GAP85388.1 - 0.007 15.9 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP85388.1 - 0.017 15.5 0.0 0.1 13.0 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.13 GAP85388.1 - 0.091 11.8 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 GAP85388.1 - 0.12 12.8 0.0 0.48 10.9 0.0 2.2 1 0 0 1 1 1 0 Methyltransferase domain RRN9 PF10680.4 GAP85389.1 - 2.8e-17 62.1 0.2 2.8e-17 62.1 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor Peptidase_M35 PF02102.10 GAP85389.1 - 0.085 11.4 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family Pescadillo_N PF06732.6 GAP85390.1 - 3.1e-113 377.7 0.1 3.1e-113 377.7 0.0 1.9 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 GAP85390.1 - 2.7e-11 43.4 0.0 7e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PIG-U PF06728.8 GAP85391.1 - 3.5e-120 401.3 32.3 3.9e-120 401.2 22.4 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U MFS_1 PF07690.11 GAP85392.1 - 6.7e-34 117.1 42.5 8.6e-34 116.7 25.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.14 GAP85393.1 - 4.3e-11 42.4 0.0 0.0013 17.8 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 GAP85393.1 - 0.00018 21.4 0.0 0.0004 20.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAP85393.1 - 0.00027 19.9 0.8 0.011 14.6 0.1 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAP85393.1 - 0.0044 17.3 0.0 0.15 12.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 GAP85393.1 - 0.076 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.9 GAP85393.1 - 0.16 11.8 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Tom37_C PF11801.3 GAP85395.1 - 1.7e-20 73.5 0.0 2.2e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 GAP85395.1 - 3.1e-19 69.0 0.1 5.9e-19 68.1 0.1 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 GAP85395.1 - 0.0011 18.7 0.1 0.0093 15.8 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1 PF00133.17 GAP85397.1 - 6.1e-156 519.9 0.0 9e-156 519.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 GAP85397.1 - 1.9e-21 76.2 0.0 8.5e-12 44.4 0.0 3.9 4 0 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 GAP85397.1 - 2.7e-15 56.4 0.0 5.2e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.9 GAP85397.1 - 5.8e-05 22.6 5.1 0.00013 21.5 3.6 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.1 GAP85397.1 - 0.012 14.9 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 GAP85397.1 - 0.022 13.8 0.0 1 8.3 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DUF945 PF06097.6 GAP85397.1 - 0.24 10.1 0.0 0.39 9.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) Kinesin PF00225.18 GAP85399.1 - 5.2e-108 360.7 0.4 9.3e-108 359.8 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bind PF13931.1 GAP85399.1 - 4.3e-08 33.4 1.5 4.3e-08 33.4 1.0 4.9 4 2 1 6 6 6 1 Kinesin-associated microtubule-binding Prominin PF05478.6 GAP85399.1 - 3.1 5.2 20.7 0.061 10.8 0.3 2.5 2 1 0 2 2 2 0 Prominin UPF0183 PF03676.9 GAP85400.1 - 1.2e-39 136.0 0.0 5.2e-25 87.8 0.0 4.8 4 1 0 4 4 4 4 Uncharacterised protein family (UPF0183) Epimerase PF01370.16 GAP85401.1 - 7.3e-12 45.2 0.5 1.9e-11 43.8 0.3 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAP85401.1 - 4.8e-05 23.4 6.0 0.012 15.6 0.9 3.2 2 1 1 3 3 3 2 NADH(P)-binding NmrA PF05368.8 GAP85401.1 - 0.0023 17.1 0.6 0.0042 16.3 0.4 1.4 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 GAP85401.1 - 0.0073 15.0 0.1 0.013 14.1 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family FMO-like PF00743.14 GAP85402.1 - 4.9e-56 190.0 0.0 1.3e-53 182.0 0.0 3.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 GAP85402.1 - 1.9e-22 80.3 0.0 1.2e-21 77.7 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAP85402.1 - 3.7e-09 36.8 0.0 0.00037 20.8 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP85402.1 - 2e-08 34.1 0.1 6.2e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAP85402.1 - 5.7e-08 32.8 0.0 1.8e-07 31.2 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAP85402.1 - 2.8e-07 29.7 0.0 5.1e-05 22.3 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 GAP85402.1 - 1.7e-06 27.9 2.3 0.0048 16.6 0.1 3.9 3 1 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.19 GAP85402.1 - 3.1e-05 23.0 0.0 0.0022 16.9 0.0 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 GAP85402.1 - 0.00021 21.5 0.0 0.6 10.3 0.0 2.6 2 0 0 2 2 2 2 Putative NAD(P)-binding Thi4 PF01946.12 GAP85402.1 - 0.00067 18.8 0.1 0.0014 17.7 0.0 1.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 GAP85402.1 - 0.00096 18.2 0.0 0.0024 17.0 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 GAP85402.1 - 0.0016 17.0 0.1 0.0028 16.2 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Shikimate_DH PF01488.15 GAP85402.1 - 0.0017 18.4 0.0 3.9 7.5 0.0 2.9 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 GAP85402.1 - 0.0055 15.6 0.0 0.0084 14.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain IlvN PF07991.7 GAP85402.1 - 0.021 14.1 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_10 PF13460.1 GAP85402.1 - 0.088 12.8 0.1 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 NADH(P)-binding FAD_oxidored PF12831.2 GAP85402.1 - 0.11 11.5 2.5 0.13 11.2 0.0 2.1 2 1 0 2 2 2 0 FAD dependent oxidoreductase CPSase_L_chain PF00289.17 GAP85402.1 - 0.13 12.3 0.0 0.7 10.0 0.0 2.1 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain AlaDh_PNT_C PF01262.16 GAP85402.1 - 0.18 11.3 0.1 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Cep57_MT_bd PF06657.8 GAP85403.1 - 3.6e-14 52.4 0.4 3.6e-14 52.4 0.3 4.7 4 1 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 GAP85403.1 - 1.4e-08 34.5 7.9 1.4e-08 34.5 5.5 5.0 3 1 2 5 5 5 3 Centrosome localisation domain of PPC89 Tropomyosin_1 PF12718.2 GAP85403.1 - 0.14 12.0 44.1 0.098 12.5 5.7 4.1 2 1 2 4 4 4 0 Tropomyosin like WXG100 PF06013.7 GAP85403.1 - 2.8 8.0 16.6 0.062 13.3 2.5 3.7 3 0 0 3 3 3 0 Proteins of 100 residues with WXG TMF_DNA_bd PF12329.3 GAP85403.1 - 3.8 7.4 37.9 0.084 12.6 0.6 5.3 5 0 0 5 5 5 0 TATA element modulatory factor 1 DNA binding RRM_1 PF00076.17 GAP85404.1 - 8.1e-13 47.8 0.0 1.2e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP85404.1 - 1.9e-09 37.3 0.0 3.2e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP85404.1 - 7.7e-08 32.0 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc PF12871.2 GAP85404.1 - 0.086 13.3 22.8 0.14 12.6 15.8 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Transformer PF06495.6 GAP85404.1 - 0.45 10.3 11.0 0.65 9.8 7.6 1.2 1 0 0 1 1 1 0 Fruit fly transformer protein DUF1777 PF08648.7 GAP85404.1 - 1 9.0 20.4 1.5 8.5 14.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF1509 PF07420.6 GAP85404.1 - 3.2 6.9 10.3 1.9 7.6 6.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1509) UQ_con PF00179.21 GAP85405.1 - 2.3e-25 88.6 0.1 3.8e-25 87.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 GAP85405.1 - 0.0016 18.2 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 GAP85405.1 - 0.031 14.0 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.8 GAP85405.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 UEV domain zf-DHHC PF01529.15 GAP85406.1 - 2.4e-31 108.4 0.0 1e-30 106.4 0.0 1.8 1 1 0 1 1 1 1 DHHC palmitoyltransferase DUF2890 PF11081.3 GAP85406.1 - 0.035 14.1 0.3 0.045 13.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Oxidored_q2 PF00420.19 GAP85406.1 - 0.052 13.1 1.1 0.095 12.3 0.8 1.4 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Transglut_core3 PF13471.1 GAP85406.1 - 0.065 13.0 6.2 0.084 12.6 3.2 1.9 2 0 0 2 2 2 0 Transglutaminase-like superfamily DZR PF12773.2 GAP85406.1 - 0.14 12.0 8.4 0.25 11.1 5.8 1.3 1 0 0 1 1 1 0 Double zinc ribbon Nop14 PF04147.7 GAP85406.1 - 0.75 7.6 8.7 0.92 7.3 6.1 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 GAP85406.1 - 2.5 6.0 8.2 3.4 5.5 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein COPI_C PF06957.6 GAP85406.1 - 6.9 5.0 5.5 9.6 4.6 3.8 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Myosin_head PF00063.16 GAP85408.1 - 2e-231 769.7 3.7 3e-231 769.2 2.6 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 GAP85408.1 - 1.1e-36 126.0 0.0 2.4e-36 124.9 0.0 1.6 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 GAP85408.1 - 3.1e-13 48.8 0.1 6.4e-13 47.8 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAP85408.1 - 1.2e-11 43.9 0.1 2.8e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAP85408.1 - 3.2e-09 36.1 0.0 1.7e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain IQ PF00612.22 GAP85408.1 - 0.0015 17.9 10.9 0.042 13.5 2.3 2.8 1 1 1 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.1 GAP85408.1 - 0.0057 16.7 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 GAP85408.1 - 0.016 14.3 0.0 0.036 13.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin SH3_3 PF08239.6 GAP85408.1 - 0.024 14.7 0.3 0.064 13.4 0.2 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain Hpr_kinase_C PF07475.7 GAP85408.1 - 0.031 13.6 0.5 2.5 7.3 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain DUF552 PF04472.7 GAP85408.1 - 0.067 13.1 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF552) AAA_17 PF13207.1 GAP85408.1 - 0.074 13.8 0.0 0.21 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 GAP85408.1 - 0.075 13.3 0.7 0.35 11.1 0.0 2.4 3 0 0 3 3 2 0 ABC transporter AAA_19 PF13245.1 GAP85408.1 - 0.087 12.5 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 GAP85408.1 - 0.11 12.8 0.1 0.33 11.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 GAP85408.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.16 GAP85408.1 - 0.17 11.0 0.0 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI FAD_binding_8 PF08022.7 GAP85410.1 - 6.5e-23 80.6 0.0 1.4e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 GAP85410.1 - 2.1e-22 79.7 0.0 3.5e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 GAP85410.1 - 1.5e-19 70.3 8.4 3.3e-19 69.2 5.8 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 GAP85410.1 - 9.4e-05 22.4 0.0 0.00029 20.9 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain LrgA PF03788.9 GAP85410.1 - 0.025 14.2 0.0 0.075 12.7 0.0 1.7 1 0 0 1 1 1 0 LrgA family NAD_binding_1 PF00175.16 GAP85410.1 - 0.16 12.5 0.0 3 8.4 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF2975 PF11188.3 GAP85410.1 - 3.2 7.4 5.0 0.71 9.5 0.7 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) Solute_trans_a PF03619.11 GAP85411.1 - 3.6e-30 105.2 3.2 5.4e-30 104.6 2.2 1.3 1 0 0 1 1 1 1 Organic solute transporter Ostalpha NOA36 PF06524.7 GAP85411.1 - 5.1 6.2 7.2 8.2 5.5 5.0 1.2 1 0 0 1 1 1 0 NOA36 protein DUF829 PF05705.9 GAP85412.1 - 1.8e-53 181.7 0.0 2.1e-53 181.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) F-box PF00646.28 GAP85413.1 - 0.03 13.9 0.2 0.23 11.1 0.0 2.5 2 0 0 2 2 2 0 F-box domain fn3 PF00041.16 GAP85414.1 - 3.6e-07 30.2 0.0 8.9e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain GAS PF13851.1 GAP85414.1 - 1.5 7.9 33.6 3.5 6.7 23.3 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.14 GAP85414.1 - 1.7 6.4 17.7 3 5.5 12.3 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GST_N_3 PF13417.1 GAP85415.1 - 8e-08 32.4 0.0 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAP85415.1 - 3.5e-06 26.9 0.0 6.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAP85415.1 - 0.0011 18.7 0.0 0.003 17.4 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAP85415.1 - 0.029 14.8 0.0 0.06 13.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Cyt-b5 PF00173.23 GAP85416.1 - 7.5e-16 57.6 0.0 1e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FHA PF00498.21 GAP85417.1 - 3.2e-09 36.7 0.0 7e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 FHA domain HET PF06985.6 GAP85418.1 - 4e-22 78.8 0.0 8.4e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Zip PF02535.17 GAP85419.1 - 0.024 13.6 0.1 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 GAP85419.1 - 3.3 7.0 8.3 4.1 6.7 5.8 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF2668 PF10873.3 GAP85419.1 - 7 6.7 6.6 3.9 7.6 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2668) Acetyltransf_1 PF00583.19 GAP85420.1 - 6.6e-13 48.4 0.0 1.1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAP85420.1 - 1.1e-05 25.5 0.0 1.7e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAP85420.1 - 1.5e-05 25.0 0.0 2.5e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAP85420.1 - 5.6e-05 22.8 0.0 9.5e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 GAP85420.1 - 0.00061 19.6 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAP85420.1 - 0.0016 18.6 0.0 0.0034 17.5 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAP85420.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PALP PF00291.20 GAP85421.1 - 6.2e-73 245.6 0.5 7.8e-73 245.3 0.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 GAP85421.1 - 8.5e-44 147.0 0.0 3.5e-21 74.5 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Glyco_hydro_47 PF01532.15 GAP85422.1 - 6.5e-163 542.5 0.0 7.7e-163 542.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Med15 PF09606.5 GAP85423.1 - 0.0092 14.2 17.4 0.011 13.9 12.0 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1689 PF07954.6 GAP85423.1 - 0.013 15.3 2.4 2.8 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) Zip PF02535.17 GAP85423.1 - 0.028 13.4 0.4 0.059 12.3 0.0 1.7 2 1 0 2 2 2 0 ZIP Zinc transporter Suf PF05843.9 GAP85423.1 - 0.28 10.8 6.0 0.37 10.4 4.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3371 PF11851.3 GAP85423.1 - 0.36 11.5 10.6 0.59 10.8 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) Med3 PF11593.3 GAP85423.1 - 0.4 9.8 9.2 0.61 9.2 6.3 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Activator_LAG-3 PF11498.3 GAP85423.1 - 0.63 8.7 28.8 0.85 8.2 19.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 BAF1_ABF1 PF04684.8 GAP85423.1 - 0.65 8.7 21.9 0.86 8.3 15.2 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF3682 PF12446.3 GAP85423.1 - 1.3 9.2 11.4 2 8.6 7.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Spt20 PF12090.3 GAP85423.1 - 1.8 7.8 9.6 3 7.1 6.7 1.2 1 0 0 1 1 1 0 Spt20 family FimP PF09766.4 GAP85423.1 - 1.9 7.4 13.0 2.6 7.0 9.0 1.1 1 0 0 1 1 1 0 Fms-interacting protein Dicty_REP PF05086.7 GAP85423.1 - 1.9 6.1 6.1 2.5 5.7 4.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pex14_N PF04695.8 GAP85423.1 - 2.7 8.0 11.0 6.1 6.8 7.6 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2967 PF11179.3 GAP85423.1 - 3.8 6.9 9.5 5.6 6.3 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DUF4557 PF15101.1 GAP85423.1 - 7.6 6.3 12.8 6.1 6.6 7.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Histidinol_dh PF00815.15 GAP85424.1 - 1e-180 600.8 5.5 1.4e-180 600.3 3.8 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 GAP85424.1 - 1.1e-25 89.0 0.1 2.1e-25 88.1 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 GAP85424.1 - 1e-10 41.6 0.7 2.4e-10 40.5 0.1 2.0 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase TFIID-31kDa PF02291.10 GAP85425.1 - 1.2e-23 83.3 0.0 2.2e-12 46.8 0.0 2.1 2 0 0 2 2 2 2 Transcription initiation factor IID, 31kD subunit Serglycin PF04360.7 GAP85425.1 - 0.44 10.2 4.8 6.1 6.5 0.0 2.4 1 1 0 2 2 2 0 Serglycin DUF2457 PF10446.4 GAP85425.1 - 3.6 6.2 8.9 4.9 5.7 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) LNS2 PF08235.8 GAP85426.1 - 1.8e-70 235.5 0.0 2.7e-70 234.9 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 GAP85426.1 - 3.3e-39 132.9 0.0 1.1e-38 131.2 0.0 1.9 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 GAP85426.1 - 0.0012 18.2 0.2 0.31 10.3 0.0 2.5 3 0 0 3 3 3 2 HAD superfamily, subfamily IIIB (Acid phosphatase) zf-C2H2 PF00096.21 GAP85428.1 - 7.8e-06 25.9 3.5 0.03 14.6 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP85428.1 - 0.00029 20.9 1.8 0.053 13.8 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAP85428.1 - 0.028 14.5 2.4 5.3 7.3 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding EcsC PF12787.2 GAP85428.1 - 0.054 12.8 0.2 0.092 12.1 0.1 1.3 1 0 0 1 1 1 0 EcsC protein family zf-Di19 PF05605.7 GAP85428.1 - 0.071 13.2 1.0 2.2 8.4 0.6 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 GAP85428.1 - 0.16 11.9 3.0 3.8 7.5 0.0 2.4 1 1 1 2 2 2 0 C2H2-type zinc finger Pkinase PF00069.20 GAP85434.1 - 8.8e-71 238.0 0.0 1.4e-70 237.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP85434.1 - 2.5e-33 115.2 0.0 6.5e-32 110.6 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP85434.1 - 0.0003 19.8 0.2 0.37 9.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 GAP85434.1 - 0.011 15.4 0.1 0.29 10.8 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 GAP85434.1 - 0.039 13.3 1.8 0.098 11.9 1.2 1.6 1 1 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 GAP85434.1 - 0.11 11.2 0.6 0.43 9.3 0.1 1.9 1 1 1 2 2 2 0 Poxvirus serine/threonine protein kinase DUF2201_N PF13203.1 GAP85436.1 - 3.8 6.6 7.5 5.8 5.9 5.2 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Zn_clus PF00172.13 GAP85437.1 - 1.1e-07 31.6 4.7 1.1e-07 31.6 3.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAP85437.1 - 0.0039 15.8 0.0 0.0049 15.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 GAP85438.1 - 1.6e-37 129.1 0.6 2.4e-37 128.5 0.4 1.2 1 0 0 1 1 1 1 RTA1 like protein Isochorismatase PF00857.15 GAP85438.1 - 8.7e-30 103.9 0.0 1.9e-29 102.8 0.0 1.6 1 1 0 1 1 1 1 Isochorismatase family SNF2_N PF00176.18 GAP85440.1 - 2e-70 236.9 0.3 2.9e-70 236.4 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAP85440.1 - 2.4e-11 43.3 0.0 6.4e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAP85440.1 - 4.8e-11 42.8 0.3 1.9e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 GAP85440.1 - 6e-09 35.6 0.0 1.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.1 GAP85440.1 - 5.3e-08 32.7 5.5 6.3e-08 32.5 2.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAP85440.1 - 3.7e-07 29.6 1.3 1.1e-06 28.1 0.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAP85440.1 - 1.7e-06 27.6 3.1 1.7e-06 27.6 2.1 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAP85440.1 - 1.3e-05 24.8 3.0 4.7e-05 23.0 2.1 2.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 GAP85440.1 - 0.00018 21.2 5.1 0.00028 20.6 2.7 2.0 2 0 0 2 2 1 1 Ring finger domain zf-MYND PF01753.13 GAP85440.1 - 0.00041 20.1 5.6 0.00041 20.1 3.9 2.0 2 0 0 2 2 2 1 MYND finger AAA_34 PF13872.1 GAP85440.1 - 0.00058 18.7 0.0 0.0012 17.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 HDA2-3 PF11496.3 GAP85440.1 - 0.00076 18.3 2.2 0.19 10.5 0.0 3.2 3 1 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 zf-C3HC4_4 PF15227.1 GAP85440.1 - 0.0017 18.1 5.2 0.0049 16.7 3.6 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 GAP85440.1 - 0.0039 16.8 0.8 0.012 15.2 0.6 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 GAP85440.1 - 0.0039 16.6 2.6 0.0055 16.1 1.1 1.8 2 0 0 2 2 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 GAP85440.1 - 5.6 6.8 9.2 0.17 11.6 0.5 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Amidohydro_4 PF13147.1 GAP85441.1 - 2.3e-25 90.1 8.7 3.9e-16 59.8 0.3 2.3 1 1 1 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 GAP85441.1 - 6.3e-16 58.9 0.1 9.3e-12 45.2 0.0 2.2 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 GAP85441.1 - 3e-13 49.7 10.3 2.2e-11 43.6 3.5 2.3 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 GAP85441.1 - 2e-10 40.2 0.5 7.1e-10 38.5 0.4 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 GAP85441.1 - 0.031 13.8 0.2 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Amidohydrolase Fungal_trans_2 PF11951.3 GAP85442.1 - 3.6e-06 25.8 0.9 5.9e-06 25.1 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain CUE PF02845.11 GAP85444.1 - 0.015 14.7 0.2 0.072 12.6 0.0 2.1 2 0 0 2 2 2 0 CUE domain Memo PF01875.12 GAP85445.1 - 1.8e-74 250.1 0.0 2e-74 249.9 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein SNARE PF05739.14 GAP85446.1 - 2.3e-11 43.1 8.1 2.3e-11 43.1 5.6 3.4 3 1 2 5 5 5 1 SNARE domain Syntaxin PF00804.20 GAP85446.1 - 3.9e-06 26.9 7.0 3.9e-06 26.9 4.9 2.7 1 1 0 2 2 2 1 Syntaxin DUF2866 PF11065.3 GAP85446.1 - 0.03 14.2 0.2 0.078 12.9 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2866) YqaJ PF09588.5 GAP85446.1 - 0.032 14.1 0.3 0.049 13.5 0.2 1.4 1 0 0 1 1 1 0 YqaJ-like viral recombinase domain DUF1664 PF07889.7 GAP85446.1 - 0.038 13.7 9.7 0.081 12.7 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF2207 PF09972.4 GAP85446.1 - 0.11 11.1 0.0 0.11 11.1 0.0 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Rifin_STEVOR PF02009.11 GAP85446.1 - 0.17 11.4 8.6 0.35 10.4 5.6 1.7 1 1 0 1 1 1 0 Rifin/stevor family Allexi_40kDa PF05549.6 GAP85446.1 - 0.35 10.1 7.4 0.42 9.8 0.7 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF4094 PF13334.1 GAP85446.1 - 0.61 10.5 8.9 1 9.7 0.6 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4094) Baculo_p24 PF05073.7 GAP85446.1 - 0.85 9.1 6.6 2.5 7.6 0.4 2.3 2 0 0 2 2 2 0 Baculovirus P24 capsid protein DUF1993 PF09351.5 GAP85446.1 - 1.4 8.7 8.0 0.24 11.3 1.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1993) DUF2203 PF09969.4 GAP85446.1 - 1.7 8.8 12.3 1.8 8.7 1.1 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) AAA_13 PF13166.1 GAP85446.1 - 2.3 6.5 12.2 4 5.7 7.0 1.9 1 1 1 2 2 2 0 AAA domain YlqD PF11068.3 GAP85446.1 - 3.2 7.7 26.7 0.27 11.2 0.5 3.2 1 1 1 2 2 1 0 YlqD protein Laminin_II PF06009.7 GAP85446.1 - 3.6 7.3 12.1 2.7 7.7 1.5 2.6 2 1 0 2 2 2 0 Laminin Domain II DUF2562 PF10814.3 GAP85446.1 - 3.9 7.4 7.1 0.53 10.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2562) V-SNARE PF05008.10 GAP85446.1 - 8 6.7 16.1 0.47 10.6 2.3 3.9 2 2 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus DUF1308 PF07000.6 GAP85447.1 - 0.012 14.3 0.0 0.024 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) zf-Apc11 PF12861.2 GAP85448.1 - 1.7e-45 152.8 12.0 1.9e-45 152.5 8.3 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 GAP85448.1 - 1.9e-33 114.3 11.1 2.3e-33 114.1 7.7 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 GAP85448.1 - 8.7e-09 35.0 16.4 5.1e-08 32.6 11.4 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 GAP85448.1 - 0.0001 21.8 13.0 0.00012 21.6 5.8 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAP85448.1 - 0.00015 21.6 14.0 0.001 19.0 9.7 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAP85448.1 - 0.00025 20.6 14.4 0.001 18.7 10.0 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAP85448.1 - 0.00041 20.1 4.5 0.00041 20.1 3.1 2.3 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 GAP85448.1 - 0.0013 18.2 3.6 0.0013 18.2 2.5 2.3 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 GAP85448.1 - 0.0023 17.8 16.4 0.043 13.7 11.4 3.0 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_5 PF14634.1 GAP85448.1 - 0.013 15.2 16.5 0.27 10.9 11.8 2.6 1 1 1 2 2 2 0 zinc-RING finger domain zf-Nse PF11789.3 GAP85448.1 - 0.052 13.0 6.5 0.1 12.1 4.5 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-HIT PF04438.11 GAP85448.1 - 0.067 12.8 1.0 0.067 12.8 0.7 2.3 2 0 0 2 2 2 0 HIT zinc finger DUF1706 PF08020.6 GAP85448.1 - 0.12 11.8 0.1 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) zf-DBF PF07535.7 GAP85448.1 - 0.26 10.9 2.3 1.7 8.3 0.1 2.3 2 0 0 2 2 2 0 DBF zinc finger zf-RING_UBOX PF13445.1 GAP85448.1 - 0.27 11.0 5.9 0.27 10.9 2.9 2.0 1 1 0 1 1 1 0 RING-type zinc-finger Opy2 PF09463.5 GAP85448.1 - 0.48 10.5 11.3 2.5 8.2 4.5 2.3 2 0 0 2 2 2 0 Opy2 protein DUF329 PF03884.9 GAP85448.1 - 0.48 10.0 0.1 0.48 10.0 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF329) RINGv PF12906.2 GAP85448.1 - 1.6 8.8 13.0 4.4 7.4 8.7 2.1 1 1 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.6 GAP85448.1 - 1.6 8.8 14.3 7.5 6.6 9.9 2.1 1 1 0 1 1 1 0 RING-like domain zinc-ribbons_6 PF07191.7 GAP85448.1 - 4.8 7.0 10.8 2.2 8.1 0.1 2.6 1 1 2 3 3 3 0 zinc-ribbons DZR PF12773.2 GAP85448.1 - 5.2 6.9 13.2 13 5.6 4.2 2.3 1 1 1 2 2 2 0 Double zinc ribbon zf-HC5HC2H_2 PF13832.1 GAP85448.1 - 5.6 7.0 10.8 2.7 8.0 4.4 2.2 1 1 1 2 2 2 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 GAP85448.1 - 9.7 6.4 12.3 3.3 7.9 4.6 2.4 1 1 1 2 2 2 0 PHD-like zinc-binding domain Rhodanese PF00581.15 GAP85449.1 - 4.4e-23 81.7 0.0 6.1e-13 49.1 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain PGM_PMM_II PF02879.11 GAP85449.1 - 0.026 14.8 0.0 0.43 10.9 0.0 2.5 3 1 0 3 3 3 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II WSC PF01822.14 GAP85450.1 - 2.9e-16 59.1 8.0 2.9e-16 59.1 5.5 3.0 3 0 0 3 3 3 1 WSC domain Ribosomal_S5 PF00333.15 GAP85451.1 - 2.1e-28 97.8 3.8 2.2e-28 97.7 1.4 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 GAP85451.1 - 2.8e-20 71.3 0.0 5.1e-20 70.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Cyclin_N PF00134.18 GAP85452.1 - 3.3e-37 126.8 1.0 4.8e-37 126.3 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 GAP85452.1 - 1.2e-12 47.7 0.2 5.6e-12 45.6 0.2 2.1 1 1 0 1 1 1 1 Cyclin, C-terminal domain Phosducin PF02114.11 GAP85453.1 - 0.031 12.9 2.6 0.059 12.0 1.8 1.3 1 0 0 1 1 1 0 Phosducin ADH_zinc_N_2 PF13602.1 GAP85455.1 - 3.1e-06 28.0 0.4 6.8e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP85455.1 - 0.0073 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glyco_hydro_76 PF03663.9 GAP85456.1 - 4.9e-66 223.6 19.5 5.8e-66 223.3 13.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_76 PF03663.9 GAP85457.1 - 1.4e-21 77.3 0.0 1.6e-21 77.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 RasGAP_C PF03836.10 GAP85458.1 - 1.3e-47 161.1 2.0 1.3e-47 161.1 1.4 2.4 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.14 GAP85458.1 - 7.4e-42 143.2 0.0 2e-41 141.8 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 GAP85458.1 - 1.6e-19 67.6 30.5 0.0011 18.4 0.4 12.6 12 0 0 12 12 12 9 IQ calmodulin-binding motif CH PF00307.26 GAP85458.1 - 0.00011 22.1 0.0 0.00038 20.4 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain IMPDH PF00478.20 GAP85459.1 - 4.2e-131 437.0 3.1 5.3e-131 436.6 2.1 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 GAP85459.1 - 2e-12 46.6 0.0 1.3e-05 24.8 0.1 2.4 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 GAP85459.1 - 2.7e-09 36.3 1.7 9.1e-08 31.3 0.5 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 GAP85459.1 - 3.7e-06 26.3 9.2 0.0035 16.5 6.4 2.5 1 1 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 GAP85459.1 - 0.0027 17.0 2.4 0.032 13.5 1.6 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein DUF1273 PF06908.6 GAP85459.1 - 0.099 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) ThiG PF05690.9 GAP85459.1 - 0.11 11.5 3.4 0.17 10.9 0.8 2.1 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG MFS_1 PF07690.11 GAP85460.1 - 4.2e-37 127.6 25.2 5.2e-25 87.9 4.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TFR_dimer PF04253.10 GAP85461.1 - 3.2e-19 68.7 0.0 5.3e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 GAP85461.1 - 5.5e-16 58.8 0.0 1.1e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 GAP85461.1 - 5.4e-06 26.0 0.1 1.4e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 GAP85461.1 - 0.0056 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 GAP85461.1 - 0.017 14.3 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Nicastrin Tenui_PVC2 PF06656.6 GAP85462.1 - 0.018 12.9 4.6 0.019 12.7 3.2 1.1 1 0 0 1 1 1 0 Tenuivirus PVC2 protein Bunya_G2 PF03563.8 GAP85462.1 - 0.52 9.1 5.4 0.79 8.5 3.7 1.3 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 Sigma_reg_N PF13800.1 GAP85462.1 - 1 9.4 7.0 1.6 8.7 4.9 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal ASFV_J13L PF05568.6 GAP85462.1 - 3.9 6.9 10.3 7.2 6.0 7.2 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Baculo_E56 PF04639.7 GAP85462.1 - 5.7 5.5 9.3 8.6 4.9 6.4 1.2 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope DUF3753 PF12575.3 GAP85462.1 - 5.8 6.7 12.8 13 5.6 8.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) TMEM154 PF15102.1 GAP85462.1 - 6.3 6.4 12.3 12 5.6 8.3 1.5 2 0 0 2 2 2 0 TMEM154 protein family Synaptobrevin PF00957.16 GAP85462.1 - 6.4 6.4 13.1 5.8 6.5 8.1 1.6 2 0 0 2 2 2 0 Synaptobrevin Grp1_Fun34_YaaH PF01184.14 GAP85463.1 - 3.6e-83 278.0 19.2 4.4e-83 277.7 13.3 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Translin PF01997.11 GAP85464.1 - 8.8e-47 159.2 0.0 1.2e-46 158.9 0.0 1.1 1 0 0 1 1 1 1 Translin family PaaX_C PF08223.6 GAP85464.1 - 0.084 12.5 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain NPV_P10 PF05531.7 GAP85464.1 - 0.13 12.4 0.1 1.1 9.5 0.0 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Mannosyl_trans PF05007.8 GAP85465.1 - 5.1e-74 249.1 0.9 9.5e-74 248.3 0.6 1.4 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 GAP85465.1 - 1.3e-13 50.5 0.2 5.1e-13 48.6 0.0 1.9 1 1 0 2 2 2 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 GAP85465.1 - 9.1e-08 31.8 14.8 9.1e-08 31.8 10.3 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF2029) DUF3619 PF12279.3 GAP85465.1 - 0.053 13.5 0.1 0.38 10.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) F-box-like PF12937.2 GAP85466.1 - 2.5e-05 23.8 0.8 2.5e-05 23.8 0.5 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 GAP85466.1 - 0.52 10.0 3.6 2.8 7.7 0.4 3.1 3 0 0 3 3 3 0 F-box domain Peptidase_S8 PF00082.17 GAP85467.1 - 9.1e-43 146.4 12.9 1.4e-42 145.7 8.9 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 GAP85467.1 - 0.15 12.6 0.4 0.32 11.6 0.3 1.6 1 0 0 1 1 1 0 Peptidase inhibitor I9 SQS_PSY PF00494.14 GAP85468.1 - 4.5e-38 131.0 0.0 9.4e-38 130.0 0.0 1.5 2 0 0 2 2 2 1 Squalene/phytoene synthase ADH_N PF08240.7 GAP85469.1 - 7.2e-12 45.0 0.2 1.3e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAP85469.1 - 4e-08 32.8 0.4 7.5e-08 31.9 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 GAP85469.1 - 0.0063 16.5 1.4 0.01 15.8 1.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAP85469.1 - 0.025 14.0 0.1 0.04 13.3 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ank PF00023.25 GAP85470.1 - 1.2e-18 65.9 0.0 2.2e-06 27.1 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 GAP85470.1 - 4.7e-18 65.3 0.0 5.8e-10 39.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAP85470.1 - 1.5e-13 49.5 0.0 0.0025 17.8 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 GAP85470.1 - 4.6e-12 46.0 0.0 7.8e-08 32.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP85470.1 - 6.2e-12 45.3 0.0 0.00025 21.1 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) NmrA PF05368.8 GAP85471.1 - 2.5e-30 105.4 0.0 1e-29 103.4 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAP85471.1 - 3.4e-07 30.4 0.0 4.9e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 GAP85471.1 - 0.0082 16.1 0.1 0.021 14.8 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain Semialdhyde_dh PF01118.19 GAP85471.1 - 0.063 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DNA_pol_B_2 PF03175.8 GAP85471.1 - 0.18 10.4 0.0 0.27 9.8 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Tubulin PF00091.20 GAP85472.1 - 1.4e-54 185.1 0.0 2.3e-35 122.3 0.0 2.6 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 GAP85472.1 - 8.6e-42 142.1 0.4 1.8e-41 141.0 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 GAP85472.1 - 4e-05 23.6 0.0 9.2e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 GAP85472.1 - 0.0029 17.1 0.0 0.0056 16.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain IBR PF01485.16 GAP85473.1 - 3.3e-10 39.6 39.2 5.8e-07 29.2 4.2 4.2 3 1 0 3 3 3 2 IBR domain zf-CCCH PF00642.19 GAP85473.1 - 3.1e-08 33.1 9.9 3.5e-05 23.3 1.9 3.1 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_UBOX PF13445.1 GAP85473.1 - 1.6e-06 27.7 4.1 7.7e-06 25.5 2.9 2.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 GAP85473.1 - 9.5e-06 25.5 6.6 9.5e-06 25.5 4.6 4.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAP85473.1 - 4.6e-05 22.9 4.5 4.6e-05 22.9 3.1 4.7 3 1 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAP85473.1 - 5.4e-05 22.9 6.8 5.4e-05 22.9 4.7 4.3 2 1 2 4 4 3 1 Ring finger domain zf-C3HC4_4 PF15227.1 GAP85473.1 - 0.00023 20.9 5.5 0.00023 20.9 3.8 4.1 3 1 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 GAP85473.1 - 0.00068 19.2 7.7 0.00068 19.2 5.3 4.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAP85473.1 - 0.00086 18.9 8.2 0.00086 18.9 5.7 4.1 2 1 1 3 3 1 1 zinc-RING finger domain RRM_6 PF14259.1 GAP85473.1 - 0.0064 16.4 0.0 0.15 12.1 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_2 PF14608.1 GAP85473.1 - 1.1 9.3 28.4 0.053 13.5 3.2 4.1 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type CGI-121 PF08617.5 GAP85474.1 - 5.3e-43 146.4 0.0 6.6e-43 146.1 0.0 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Pro_dh PF01619.13 GAP85475.1 - 9e-34 116.8 0.0 1.5e-33 116.1 0.0 1.3 1 1 0 1 1 1 1 Proline dehydrogenase Tim17 PF02466.14 GAP85476.1 - 0.059 13.4 8.9 0.23 11.5 5.9 2.0 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.4 GAP85476.1 - 0.39 10.9 3.9 3.6 7.8 0.2 3.0 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 Metallophos PF00149.23 GAP85478.1 - 3e-11 43.0 2.0 7.8e-11 41.7 1.4 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Sugar_tr PF00083.19 GAP85480.1 - 5.9e-122 407.4 19.1 6.8e-122 407.2 13.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP85480.1 - 1.9e-23 82.7 26.3 7.3e-16 57.8 2.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sulfotransfer_3 PF13469.1 GAP85481.1 - 0.0019 19.1 1.1 0.0057 17.6 0.8 1.7 1 1 0 1 1 1 1 Sulfotransferase family FRG2 PF15315.1 GAP85481.1 - 0.17 11.8 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Ribosomal_L35Ae PF01247.13 GAP85483.1 - 2.1e-37 126.7 0.1 2.3e-37 126.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 GAP85483.1 - 0.00037 20.3 0.0 0.23 11.3 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain PMSR PF01625.16 GAP85484.1 - 6.5e-60 201.5 0.6 7.7e-60 201.2 0.4 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Bax1-I PF01027.15 GAP85485.1 - 5.2e-31 107.8 11.9 7.5e-31 107.3 8.3 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 cNMP_binding PF00027.24 GAP85487.1 - 4.3e-38 128.9 0.0 9.2e-19 67.0 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 GAP85487.1 - 2.4e-14 51.7 2.3 0.21 11.7 0.0 8.1 8 0 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.28 GAP85487.1 - 2.8e-07 29.6 3.6 6.4 7.2 0.0 7.2 6 2 0 6 6 6 2 Leucine Rich Repeat LRR_8 PF13855.1 GAP85487.1 - 2.3e-06 27.2 1.5 0.15 11.8 0.1 3.9 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 GAP85487.1 - 2.6e-05 23.7 0.0 0.56 9.8 0.0 4.4 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) F-box-like PF12937.2 GAP85487.1 - 3.5e-05 23.4 1.9 3.5e-05 23.4 1.3 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 GAP85487.1 - 3.6e-05 23.3 1.0 3.6e-05 23.3 0.7 3.4 5 0 0 5 5 5 1 F-box domain Cupin_3 PF05899.7 GAP85487.1 - 0.17 11.2 0.5 16 4.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF861) LRR_7 PF13504.1 GAP85487.1 - 0.62 10.5 10.4 14 6.4 0.0 5.7 6 0 0 6 6 6 0 Leucine rich repeat ADH_zinc_N PF00107.21 GAP85488.1 - 2e-26 92.0 0.2 3.4e-26 91.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAP85488.1 - 3.7e-22 79.5 0.2 7.3e-22 78.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP85488.1 - 1.2e-05 24.9 0.2 3.4e-05 23.5 0.1 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 GAP85488.1 - 0.047 13.2 0.1 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 GAP85489.1 - 6.8e-42 143.7 0.0 2.4e-23 82.7 0.0 2.0 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAP85489.1 - 1.6e-05 24.8 0.0 4.6e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAP85489.1 - 5.1e-05 22.3 0.1 0.027 13.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAP85489.1 - 0.0011 19.1 0.0 0.0028 17.7 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAP85489.1 - 0.0012 17.3 0.0 0.0013 17.2 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 GAP85489.1 - 0.0071 15.4 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 GAP85489.1 - 0.019 13.8 0.1 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 GAP85489.1 - 0.02 15.2 0.0 0.061 13.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAP85489.1 - 0.037 12.9 0.1 0.1 11.5 0.1 1.7 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAP85489.1 - 0.08 12.7 0.2 0.39 10.4 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Sugar_tr PF00083.19 GAP85490.1 - 6.9e-13 47.9 3.6 1e-12 47.3 2.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP85490.1 - 1.2e-12 47.2 13.9 1.5e-12 46.8 9.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Ank_2 PF12796.2 GAP85491.1 - 6.1e-84 276.4 11.9 4.2e-13 49.4 0.0 10.7 2 2 8 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.25 GAP85491.1 - 2.3e-56 184.8 30.1 1.9e-06 27.4 0.0 19.1 19 1 0 19 19 19 11 Ankyrin repeat Ank_5 PF13857.1 GAP85491.1 - 1.7e-54 180.5 31.1 7.4e-10 38.7 0.0 15.0 8 3 7 15 15 15 14 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAP85491.1 - 7.6e-54 179.1 14.8 7.5e-12 45.4 0.0 15.7 10 3 6 16 16 16 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP85491.1 - 3.5e-48 156.7 20.0 0.0025 17.8 0.0 19.6 19 2 1 20 20 20 11 Ankyrin repeat ZZ PF00569.12 GAP85491.1 - 5.9e-07 28.9 11.9 1.1e-06 28.0 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Peptidase_S8 PF00082.17 GAP85492.1 - 3.6e-19 68.9 0.0 6.4e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Subtilase family Patatin PF01734.17 GAP85492.1 - 3.8e-18 66.1 0.0 1.2e-17 64.5 0.0 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase Ank_4 PF13637.1 GAP85492.1 - 0.032 14.7 0.0 0.24 11.9 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAP85492.1 - 0.093 13.0 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Na_Ca_ex PF01699.19 GAP85493.1 - 6.3e-34 116.5 26.6 9.9e-20 70.5 3.6 3.1 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF307 PF03733.8 GAP85493.1 - 6.6e-14 52.0 12.7 6.6e-14 52.0 8.8 3.9 3 0 0 3 3 3 1 Domain of unknown function (DUF307) AAA PF00004.24 GAP85494.1 - 5.2e-44 149.6 0.0 8.5e-44 148.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAP85494.1 - 3.1e-08 33.4 0.0 7.5e-08 32.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 GAP85494.1 - 1.2e-07 31.7 0.0 2.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 GAP85494.1 - 3.3e-06 27.2 0.0 9.5e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAP85494.1 - 4.7e-06 26.7 0.1 0.00025 21.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAP85494.1 - 5.9e-05 23.8 0.0 0.00015 22.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 GAP85494.1 - 7.7e-05 21.8 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 GAP85494.1 - 0.00014 21.5 0.1 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 GAP85494.1 - 0.00042 19.7 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 GAP85494.1 - 0.00091 18.0 0.0 0.0016 17.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 GAP85494.1 - 0.0014 18.5 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 GAP85494.1 - 0.0018 18.2 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 GAP85494.1 - 0.0023 17.5 0.0 0.0074 15.8 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 GAP85494.1 - 0.0024 17.0 0.0 0.0044 16.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 GAP85494.1 - 0.0038 17.2 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAP85494.1 - 0.0065 16.7 0.0 0.028 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 GAP85494.1 - 0.0068 15.5 0.0 0.017 14.2 0.0 1.6 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.16 GAP85494.1 - 0.0069 15.5 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 GAP85494.1 - 0.017 14.5 0.1 0.075 12.4 0.0 1.9 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.8 GAP85494.1 - 0.018 13.9 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 GAP85494.1 - 0.019 14.4 0.0 0.085 12.3 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain PhoH PF02562.11 GAP85494.1 - 0.019 14.1 0.0 0.07 12.3 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 GAP85494.1 - 0.021 14.4 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 GAP85494.1 - 0.029 14.5 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Histone PF00125.19 GAP85494.1 - 0.045 13.8 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Sigma54_activ_2 PF14532.1 GAP85494.1 - 0.047 13.7 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 GAP85494.1 - 0.051 12.4 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TBP PF00352.16 GAP85494.1 - 0.065 12.6 0.1 0.81 9.1 0.0 2.2 2 0 0 2 2 2 0 Transcription factor TFIID (or TATA-binding protein, TBP) NB-ARC PF00931.17 GAP85494.1 - 0.08 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 GAP85494.1 - 0.1 12.2 0.0 0.53 9.9 0.0 2.0 1 1 1 2 2 2 0 NACHT domain DUF2072 PF09845.4 GAP85494.1 - 0.12 12.3 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Y_phosphatase PF00102.22 GAP85495.1 - 6.4e-60 202.4 0.0 1e-52 178.8 0.0 3.1 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.15 GAP85495.1 - 2.5e-11 43.9 0.0 6.8e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 GAP85495.1 - 0.024 14.8 0.0 0.066 13.4 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.15 GAP85495.1 - 0.048 13.2 0.2 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain LRR_4 PF12799.2 GAP85497.1 - 1.7e-35 120.0 40.5 1.2e-07 31.1 1.5 9.1 4 3 2 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAP85497.1 - 1.3e-27 95.2 32.9 6.3e-08 32.2 1.2 6.9 5 1 0 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 GAP85497.1 - 1.7e-09 36.4 36.1 0.15 12.1 0.1 13.1 10 3 3 13 13 13 5 Leucine Rich Repeat LRR_9 PF14580.1 GAP85497.1 - 9.2e-07 28.5 6.1 0.023 14.2 0.2 4.7 3 1 2 5 5 5 2 Leucine-rich repeat LRR_7 PF13504.1 GAP85497.1 - 9.6e-05 21.9 42.1 4.7 7.8 0.1 12.6 14 0 0 14 14 14 3 Leucine rich repeat LRR_6 PF13516.1 GAP85497.1 - 0.00029 20.5 34.9 0.74 10.0 0.2 10.8 9 2 3 12 12 12 3 Leucine Rich repeat Aspzincin_M35 PF14521.1 GAP85499.1 - 0.25 11.8 1.0 3.9 7.9 0.1 2.1 2 0 0 2 2 2 0 Lysine-specific metallo-endopeptidase COesterase PF00135.23 GAP85500.1 - 6.3e-80 269.4 0.0 1.6e-72 244.9 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 GAP85500.1 - 2.8e-08 33.5 0.1 5e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP85500.1 - 3.4e-06 26.8 0.1 5.3e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP85500.1 - 0.00033 20.6 0.3 0.00061 19.7 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP85500.1 - 0.0085 15.6 0.1 0.018 14.6 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Fungal_trans_2 PF11951.3 GAP85501.1 - 1.5e-45 155.4 1.0 2.4e-45 154.8 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain AA_permease PF00324.16 GAP85502.1 - 8.2e-103 344.2 45.4 9.2e-103 344.1 31.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAP85502.1 - 3.5e-23 81.8 48.1 4.3e-23 81.5 33.4 1.1 1 0 0 1 1 1 1 Amino acid permease Orai-1 PF07856.7 GAP85502.1 - 2.4 7.6 12.1 0.076 12.5 3.4 2.0 2 0 0 2 2 2 0 Mediator of CRAC channel activity adh_short PF00106.20 GAP85503.1 - 4.7e-27 94.9 3.3 8.1e-27 94.1 2.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP85503.1 - 1.5e-22 80.5 0.4 1.8e-22 80.2 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP85503.1 - 4.6e-13 49.2 4.4 2.7e-12 46.7 3.1 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 GAP85503.1 - 0.00031 20.2 0.1 0.00051 19.5 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAP85503.1 - 0.0019 17.1 0.1 0.003 16.5 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.18 GAP85503.1 - 0.013 15.2 0.3 0.099 12.4 0.3 2.0 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 GAP85503.1 - 0.018 13.7 0.0 0.024 13.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Eno-Rase_NADH_b PF12242.3 GAP85503.1 - 0.069 12.9 0.4 0.18 11.5 0.3 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pyr_redox_3 PF13738.1 GAP85504.1 - 7.6e-20 71.8 0.0 1.4e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAP85504.1 - 6e-11 41.2 0.0 1.8e-10 39.6 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 GAP85504.1 - 3.4e-10 39.7 0.7 3.1e-08 33.5 0.0 3.3 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 GAP85504.1 - 7.8e-07 28.3 0.0 0.00011 21.2 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 GAP85504.1 - 1.9e-06 27.7 0.2 0.0021 17.8 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 GAP85504.1 - 1.9e-05 23.7 0.0 0.097 11.5 0.0 3.4 3 1 1 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.12 GAP85504.1 - 0.001 18.1 0.4 0.0067 15.5 0.0 2.3 3 0 0 3 3 3 1 Thi4 family Semialdhyde_dh PF01118.19 GAP85504.1 - 0.024 14.9 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 GAP85504.1 - 0.034 14.2 0.0 0.094 12.8 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 GAP85504.1 - 0.049 12.7 0.0 0.083 12.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short_C2 PF13561.1 GAP85505.1 - 3.2e-21 76.1 1.9 2.4e-20 73.3 1.3 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAP85505.1 - 1.3e-19 70.7 7.1 2.8e-19 69.6 4.9 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP85505.1 - 1.2e-09 38.1 7.0 3.8e-09 36.4 4.9 1.8 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 GAP85505.1 - 0.0029 17.2 0.6 0.0045 16.6 0.4 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SCPU PF05229.10 GAP85505.1 - 0.055 13.5 0.3 0.089 12.8 0.2 1.4 1 0 0 1 1 1 0 Spore Coat Protein U domain DUF3355 PF11835.3 GAP85505.1 - 0.12 12.1 0.3 0.51 10.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3355) V_ATPase_I PF01496.14 GAP85506.1 - 2.8e-298 991.0 0.0 3.1e-298 990.8 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Filament PF00038.16 GAP85506.1 - 0.022 14.2 10.6 0.13 11.6 0.8 2.5 2 1 0 2 2 2 0 Intermediate filament protein GAS PF13851.1 GAP85506.1 - 0.12 11.5 5.7 0.53 9.4 0.7 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4140 PF13600.1 GAP85506.1 - 0.28 11.6 7.3 2.3 8.6 0.4 3.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Laminin_II PF06009.7 GAP85506.1 - 0.51 10.0 4.4 9.8 5.9 0.1 2.4 2 0 0 2 2 2 0 Laminin Domain II Prefoldin_2 PF01920.15 GAP85506.1 - 0.81 9.4 6.4 5.2 6.8 0.2 2.9 3 0 0 3 3 3 0 Prefoldin subunit DUF972 PF06156.8 GAP85506.1 - 0.97 9.8 2.9 17 5.7 0.0 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF972) Seryl_tRNA_N PF02403.17 GAP85506.1 - 1.4 8.9 7.4 1.4 8.9 0.7 2.8 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain CCDC-167 PF15188.1 GAP85506.1 - 1.5 8.8 5.0 7.9 6.4 0.1 2.9 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 IncA PF04156.9 GAP85506.1 - 1.9 8.0 11.1 0.36 10.4 0.4 2.9 3 0 0 3 3 3 0 IncA protein GvpK PF05121.7 GAP85506.1 - 2.6 7.9 8.0 14 5.6 0.3 3.2 2 1 1 3 3 3 0 Gas vesicle protein K DivIC PF04977.10 GAP85506.1 - 5.5 6.5 10.3 0.23 10.9 0.2 3.2 3 0 0 3 3 3 0 Septum formation initiator FlgN PF05130.7 GAP85506.1 - 8.7 6.5 10.6 9.2 6.5 1.1 2.4 2 0 0 2 2 2 0 FlgN protein DUF4366 PF14283.1 GAP85508.1 - 0.0013 18.1 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Mucin PF01456.12 GAP85508.1 - 0.097 12.4 17.4 0.16 11.7 12.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Nup_retrotrp_bd PF10599.4 GAP85508.1 - 0.52 10.9 9.1 1.1 9.8 6.3 1.6 1 0 0 1 1 1 0 Retro-transposon transporting motif Med3 PF11593.3 GAP85508.1 - 0.79 8.9 5.6 0.84 8.8 3.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SSP160 PF06933.6 GAP85508.1 - 0.9 7.4 18.1 1.3 6.9 12.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 OmpH PF03938.9 GAP85509.1 - 0.025 14.5 3.7 2.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) PGA2 PF07543.7 GAP85511.1 - 0.045 13.5 4.8 0.12 12.2 3.3 1.6 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF4632 PF15451.1 GAP85511.1 - 0.77 9.7 8.4 25 4.8 0.0 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4632) DS PF01916.12 GAP85512.1 - 2.2e-144 480.1 0.0 2.5e-144 479.9 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Pro_isomerase PF00160.16 GAP85513.1 - 6.7e-42 143.3 0.0 1.1e-41 142.6 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HSF_DNA-bind PF00447.12 GAP85514.1 - 1e-27 96.3 0.4 1e-27 96.3 0.3 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding Nup54 PF13874.1 GAP85514.1 - 0.14 11.8 6.7 1 9.0 1.5 2.4 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Hemerythrin PF01814.18 GAP85514.1 - 0.18 11.9 1.2 0.89 9.7 0.2 2.4 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain DUF3782 PF12644.2 GAP85514.1 - 4.7 7.0 6.1 0.44 10.3 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3782) EpsG PF14897.1 GAP85515.1 - 0.036 13.0 4.4 0.063 12.1 3.1 1.3 1 0 0 1 1 1 0 EpsG family DUF3902 PF13042.1 GAP85515.1 - 1.9 7.7 12.9 0.09 12.0 4.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3902) TauD PF02668.11 GAP85516.1 - 4.4e-21 75.7 0.0 5.9e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family OTT_1508_deam PF14441.1 GAP85517.1 - 5.7e-18 65.0 0.0 9.4e-18 64.3 0.0 1.3 1 0 0 1 1 1 1 OTT_1508-like deaminase Sec6 PF06046.8 GAP85519.1 - 7.1e-158 526.2 11.8 9.1e-158 525.8 8.2 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.7 GAP85519.1 - 0.00027 19.8 1.7 0.00027 19.8 1.1 2.4 3 0 0 3 3 3 1 Vps53-like, N-terminal MutS_III PF05192.13 GAP85519.1 - 0.02 14.6 1.8 0.081 12.7 1.3 2.4 1 1 0 1 1 1 0 MutS domain III OmdA PF13376.1 GAP85519.1 - 0.099 12.3 1.7 0.36 10.5 0.0 2.7 3 0 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated NPV_P10 PF05531.7 GAP85519.1 - 0.13 12.4 3.6 17 5.7 0.8 3.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Zn_clus PF00172.13 GAP85520.1 - 5.6e-06 26.1 8.0 1e-05 25.2 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 GAP85520.1 - 0.053 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 PAS fold SnoaL_2 PF12680.2 GAP85520.1 - 0.067 13.5 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like domain SPO22 PF08631.5 GAP85521.1 - 9.9e-52 175.7 0.4 9.9e-52 175.7 0.3 3.1 3 0 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like TPR_2 PF07719.12 GAP85521.1 - 0.0032 17.2 0.6 0.13 12.2 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAP85521.1 - 0.011 15.5 3.1 0.61 10.0 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1487 PF07368.6 GAP85521.1 - 0.018 14.2 0.1 0.037 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) TPR_14 PF13428.1 GAP85521.1 - 0.032 14.8 1.0 56 4.7 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAP85521.1 - 0.039 14.2 5.0 0.54 10.6 0.1 4.1 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAP85521.1 - 0.059 14.0 0.8 22 5.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Sex_peptide PF08138.6 GAP85521.1 - 0.082 12.7 0.0 0.27 11.1 0.0 1.8 1 0 0 1 1 1 0 Sex peptide (SP) family ATG22 PF11700.3 GAP85522.1 - 2.4e-126 422.0 26.5 2.7e-126 421.8 18.4 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like SHOCT PF09851.4 GAP85522.1 - 0.039 13.4 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 Short C-terminal domain MFS_1 PF07690.11 GAP85524.1 - 1.5e-31 109.3 36.6 1.5e-31 109.3 25.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2722 PF10846.3 GAP85525.1 - 6.4e-08 32.0 2.0 9.4e-08 31.4 0.0 1.9 1 1 0 2 2 2 1 Protein of unknown function (DUF2722) Toxin_11 PF07473.6 GAP85526.1 - 0.049 13.5 1.6 0.12 12.3 1.1 1.6 1 0 0 1 1 1 0 Spasmodic peptide gm9a Tir_receptor_N PF07490.6 GAP85526.1 - 0.091 12.3 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus HATPase_c PF02518.21 GAP85527.1 - 1.7e-29 101.7 0.0 3.6e-29 100.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAP85527.1 - 1.2e-20 73.5 0.1 2.8e-20 72.3 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 GAP85527.1 - 6.1e-20 70.9 0.3 2.5e-19 69.0 0.2 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 GAP85527.1 - 8.3e-12 45.4 1.3 4.8e-11 42.9 0.3 2.8 2 1 0 2 2 2 1 AAA ATPase domain GAF_2 PF13185.1 GAP85527.1 - 3.3e-07 30.8 0.0 1.5e-06 28.7 0.0 2.2 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 GAP85527.1 - 6.1e-06 25.5 0.0 1.4e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain GAF_3 PF13492.1 GAP85527.1 - 2.7e-05 24.2 0.0 5.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.1 GAP85527.1 - 6.1e-05 22.6 0.0 0.00017 21.2 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_12 PF13424.1 GAP85527.1 - 0.0025 17.7 12.2 0.014 15.3 1.8 5.2 5 1 0 6 6 6 1 Tetratricopeptide repeat ArgK PF03308.11 GAP85527.1 - 0.021 13.6 0.1 0.039 12.7 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_22 PF13401.1 GAP85527.1 - 0.059 13.5 0.1 6.1 7.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain NAD_binding_8 PF13450.1 GAP85528.1 - 3.9e-07 29.9 0.0 7.8e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 GAP85528.1 - 2.5e-06 26.8 0.0 4.6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 GAP85528.1 - 0.0091 16.0 0.1 0.022 14.8 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAP85528.1 - 0.036 13.8 0.0 0.1 12.3 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.13 GAP85528.1 - 0.066 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.9 GAP85528.1 - 0.086 12.7 0.0 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TPT PF03151.11 GAP85529.1 - 1.2e-26 93.1 12.0 1.2e-26 93.1 8.3 2.7 3 1 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 GAP85529.1 - 0.0027 16.6 20.8 0.035 13.0 5.8 2.2 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 GAP85529.1 - 5.4 7.0 34.6 2 8.4 8.1 3.2 3 1 0 3 3 3 0 EamA-like transporter family Ribosomal_L27e PF01777.13 GAP85530.1 - 6.3e-37 125.5 3.8 8.2e-37 125.2 2.6 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 GAP85530.1 - 0.0011 18.6 0.5 0.0027 17.3 0.4 1.7 1 0 0 1 1 1 1 KOW motif TPR_11 PF13414.1 GAP85531.1 - 0.011 15.3 0.1 0.86 9.2 0.1 2.4 2 0 0 2 2 2 0 TPR repeat TPR_17 PF13431.1 GAP85531.1 - 0.079 13.1 0.0 0.67 10.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyoxalase PF00903.20 GAP85532.1 - 1.5e-22 79.9 0.1 2.1e-15 56.8 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 GAP85532.1 - 9.2e-12 44.9 0.0 6.2e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAP85532.1 - 7.5e-07 29.7 0.0 0.013 16.0 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 GAP85532.1 - 5.5e-06 26.4 0.0 0.24 11.3 0.0 3.1 3 0 0 3 3 3 3 Glyoxalase-like domain Glyoxalase_5 PF14696.1 GAP85532.1 - 0.049 13.5 0.1 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal DHQ_synthase PF01761.15 GAP85532.1 - 0.068 12.0 0.1 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 3-dehydroquinate synthase Ssl1 PF04056.9 GAP85533.1 - 6e-73 244.5 0.0 7.8e-73 244.1 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 GAP85533.1 - 6.4e-18 64.5 5.7 6.4e-18 64.5 4.0 2.9 3 1 0 3 3 3 1 TFIIH C1-like domain VWA_2 PF13519.1 GAP85533.1 - 7.9e-09 35.8 0.0 1.3e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain IBR PF01485.16 GAP85533.1 - 0.018 14.8 4.7 0.018 14.8 3.3 2.9 2 1 0 2 2 2 0 IBR domain DZR PF12773.2 GAP85533.1 - 6.9 6.5 22.6 2.5 7.9 4.0 3.4 2 1 1 3 3 3 0 Double zinc ribbon Chs3p PF12271.3 GAP85534.1 - 2.1e-100 335.5 4.8 2.4e-100 335.2 3.4 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF347 PF03988.7 GAP85534.1 - 0.43 10.5 0.0 0.43 10.5 0.0 3.8 5 0 0 5 5 5 0 Repeat of Unknown Function (DUF347) Sugar_tr PF00083.19 GAP85535.1 - 7.4e-105 351.1 14.5 8.7e-105 350.8 10.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP85535.1 - 2.3e-28 98.9 46.1 8.9e-27 93.7 14.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAP85535.1 - 9.9e-08 30.7 23.7 3.9e-05 22.2 4.1 2.6 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 GAP85535.1 - 0.00025 20.7 0.5 0.0012 18.5 0.1 2.3 2 0 0 2 2 2 1 MFS_1 like family MFS_3 PF05977.8 GAP85535.1 - 0.18 9.9 5.3 1.5 6.8 0.4 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector DUF2051 PF09738.4 GAP85535.1 - 2.2 7.4 2.7 26 3.9 0.1 2.1 2 0 0 2 2 2 0 Double stranded RNA binding protein (DUF2051) Aldedh PF00171.17 GAP85536.1 - 3.7e-131 437.6 0.0 4.3e-131 437.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAP85536.1 - 0.087 11.5 1.0 0.33 9.6 0.7 1.8 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Aminotran_1_2 PF00155.16 GAP85537.1 - 3.2e-66 223.7 0.0 3.6e-66 223.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 GAP85537.1 - 3.3e-05 23.1 0.0 7e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 GAP85537.1 - 4.1e-05 22.8 0.0 6.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 GAP85537.1 - 0.00055 18.3 0.1 0.0011 17.3 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 GAP85537.1 - 0.0095 14.7 0.1 0.026 13.2 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V DUF2407 PF10302.4 GAP85538.1 - 4e-26 91.0 0.0 6.3e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2407_C PF13373.1 GAP85538.1 - 1.8e-13 50.6 5.6 9.5e-11 41.7 0.9 2.4 1 1 1 2 2 2 2 DUF2407 C-terminal domain rRNA_proc-arch PF13234.1 GAP85539.1 - 1e-91 306.8 0.0 1.9e-91 305.9 0.0 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 GAP85539.1 - 3.1e-60 202.4 1.1 6.5e-60 201.4 0.7 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 GAP85539.1 - 4.4e-23 81.6 0.0 1.8e-22 79.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP85539.1 - 7.1e-08 32.2 0.0 1.6e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAP85539.1 - 0.0054 16.5 0.5 0.13 12.1 0.0 3.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 GAP85539.1 - 0.035 13.7 1.8 0.43 10.2 0.0 3.1 3 0 0 3 3 3 0 Archaeal ATPase T2SE PF00437.15 GAP85539.1 - 0.054 12.3 0.0 0.13 11.1 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein TSGP1 PF07771.6 GAP85539.1 - 1.7 8.5 9.2 13 5.7 0.1 2.5 2 0 0 2 2 2 0 Tick salivary peptide group 1 Metallophos PF00149.23 GAP85540.1 - 7.5e-10 38.5 0.9 1.7e-09 37.3 0.6 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAP85540.1 - 3.9e-06 26.7 0.0 7.7e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PPR_2 PF13041.1 GAP85541.1 - 5.6e-18 64.6 0.3 3.7e-07 30.0 0.1 4.6 3 1 1 4 4 4 4 PPR repeat family PPR_3 PF13812.1 GAP85541.1 - 8.1e-16 56.9 4.6 0.00036 20.5 0.0 6.7 7 0 0 7 7 7 3 Pentatricopeptide repeat domain PPR PF01535.15 GAP85541.1 - 1.3e-11 43.5 13.4 2.5e-05 23.9 0.1 5.9 5 1 0 5 5 5 3 PPR repeat PPR_1 PF12854.2 GAP85541.1 - 2.2e-06 27.0 4.2 0.1 12.0 0.0 4.7 4 1 0 4 4 4 2 PPR repeat MRP-S25 PF13741.1 GAP85542.1 - 9.5e-71 237.9 9.0 1.5e-68 230.7 6.2 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 GAP85542.1 - 6.4e-05 22.8 3.6 0.00044 20.1 2.5 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 Glyco_hydro_108 PF05838.7 GAP85542.1 - 0.015 15.4 0.1 0.04 14.0 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase 108 UPF0137 PF03677.8 GAP85542.1 - 0.17 11.3 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) MIT PF04212.13 GAP85543.1 - 1.1e-09 37.9 2.6 1.3e-09 37.7 1.8 1.0 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Fungal_trans_2 PF11951.3 GAP85543.1 - 0.011 14.3 0.2 0.012 14.2 0.2 1.0 1 0 0 1 1 1 0 Fungal specific transcription factor domain Turandot PF07240.6 GAP85543.1 - 0.078 12.4 0.1 0.097 12.1 0.1 1.2 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot RRM_1 PF00076.17 GAP85545.1 - 9.2e-46 153.3 1.0 2.7e-21 74.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP85545.1 - 6.6e-36 122.1 0.1 1.3e-18 66.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 GAP85545.1 - 2.7e-28 98.0 0.0 6e-28 96.9 0.0 1.6 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 GAP85545.1 - 4.4e-22 77.6 0.0 2.3e-09 36.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAP85545.1 - 0.00043 20.0 0.2 0.012 15.4 0.0 2.7 2 1 0 2 2 2 1 RNA binding motif MIP-T3 PF10243.4 GAP85545.1 - 0.08 11.4 21.7 0.51 8.7 15.7 1.8 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Cyt-b5 PF00173.23 GAP85546.1 - 2e-18 65.9 0.5 5.6e-18 64.5 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 GAP85546.1 - 8.3e-08 32.6 24.6 1.2e-07 32.1 16.3 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily COX14 PF14880.1 GAP85546.1 - 0.14 11.8 2.7 0.22 11.1 0.9 2.0 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Ima1_N PF09779.4 GAP85547.1 - 4.5e-31 108.0 0.2 8.5e-31 107.1 0.1 1.5 1 0 0 1 1 1 1 Ima1 N-terminal domain Zn_Tnp_IS1595 PF12760.2 GAP85547.1 - 0.0094 15.7 4.5 0.022 14.5 3.1 1.7 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Mcm10 PF09332.6 GAP85547.1 - 0.8 8.9 2.6 1.4 8.1 1.8 1.3 1 0 0 1 1 1 0 Mcm10 replication factor DZR PF12773.2 GAP85547.1 - 0.83 9.5 5.7 0.25 11.1 0.3 2.3 2 1 0 2 2 2 0 Double zinc ribbon Alg14 PF08660.6 GAP85548.1 - 1.3e-39 135.9 0.2 5.3e-39 133.9 0.0 1.8 2 0 0 2 2 2 1 Oligosaccharide biosynthesis protein Alg14 like Pex14_N PF04695.8 GAP85548.1 - 1.7 8.7 4.4 3.2 7.8 3.1 1.7 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 GAP85549.1 - 0.024 14.2 11.2 0.062 12.8 7.8 1.7 1 0 0 1 1 1 0 IncA protein Cluap1 PF10234.4 GAP85549.1 - 0.03 13.5 10.3 0.05 12.8 7.1 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF3595 PF12166.3 GAP85549.1 - 0.062 12.1 2.6 0.1 11.3 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) GAS PF13851.1 GAP85549.1 - 0.2 10.7 17.0 0.33 10.1 11.8 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CorA PF01544.13 GAP85549.1 - 0.65 8.9 4.5 1.1 8.2 3.1 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2937 PF11157.3 GAP85549.1 - 1.1 8.5 7.8 0.97 8.7 0.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) Fib_alpha PF08702.5 GAP85549.1 - 2.2 8.4 8.5 6 6.9 5.9 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TMCO5 PF14992.1 GAP85549.1 - 3.6 6.6 14.8 5.8 5.9 10.3 1.2 1 0 0 1 1 1 0 TMCO5 family ALMT PF11744.3 GAP85549.1 - 5.1 5.6 5.1 7.7 5.0 3.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF802 PF05650.6 GAP85549.1 - 8 6.6 8.7 0.93 9.6 1.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF802) adh_short PF00106.20 GAP85551.1 - 2.1e-18 66.8 0.2 3.7e-18 65.9 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP85551.1 - 9.8e-10 38.3 0.2 2.2e-09 37.2 0.1 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 GAP85551.1 - 0.00032 19.6 0.0 0.0005 19.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 GAP85551.1 - 0.011 14.6 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein VWA_2 PF13519.1 GAP85552.1 - 3.2e-08 33.8 0.0 7.6e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 GAP85552.1 - 8.1e-07 28.9 0.0 1.2e-05 25.0 0.0 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 GAP85552.1 - 0.038 13.8 0.0 0.23 11.2 0.0 2.3 2 1 0 2 2 2 0 vWA found in TerF C terminus CPSF73-100_C PF11718.3 GAP85553.1 - 1.5e-76 256.5 0.0 3.6e-73 245.5 0.0 2.2 2 0 0 2 2 2 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 GAP85553.1 - 2.8e-31 108.0 0.0 7.5e-31 106.6 0.0 1.8 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 GAP85553.1 - 3e-14 53.1 0.5 6.3e-14 52.0 0.3 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAP85553.1 - 1.8e-11 43.9 0.7 3.6e-11 42.9 0.5 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 GAP85553.1 - 1.9e-08 33.9 0.2 4.5e-08 32.7 0.1 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 GAP85553.1 - 1.1e-05 25.2 0.2 2.8e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TAF4 PF05236.9 GAP85554.1 - 4.8e-13 48.9 0.2 2.7e-10 39.9 0.0 4.0 3 1 0 3 3 3 2 Transcription initiation factor TFIID component TAF4 family CN_hydrolase PF00795.17 GAP85555.1 - 1.9e-23 82.7 0.0 4.8e-23 81.4 0.0 1.6 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase SR-25 PF10500.4 GAP85555.1 - 0.011 15.1 9.2 0.018 14.5 6.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LSM14 PF12701.2 GAP85556.1 - 1.6e-34 117.5 0.0 2.8e-34 116.7 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 GAP85556.1 - 1.6e-18 67.1 1.7 4.6e-18 65.6 1.2 1.8 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.1 GAP85556.1 - 2.2e-07 30.7 0.0 4.6e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain zf-HIT PF04438.11 GAP85557.1 - 3e-09 36.3 9.8 4.6e-09 35.7 6.8 1.3 1 0 0 1 1 1 1 HIT zinc finger DUF3366 PF11846.3 GAP85557.1 - 0.16 11.8 0.4 18 5.1 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3366) PolC_DP2 PF03833.8 GAP85557.1 - 1.8 6.0 6.5 0.9 7.1 1.1 2.0 2 0 0 2 2 2 0 DNA polymerase II large subunit DP2 Glyco_transf_8 PF01501.15 GAP85558.1 - 6.3e-25 87.9 0.0 9.3e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 GAP85558.1 - 0.043 13.1 0.0 0.082 12.2 0.0 1.4 1 0 0 1 1 1 0 Mannosyltransferase putative Ala_racemase_N PF01168.15 GAP85559.1 - 7.8e-35 120.3 0.0 1.1e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Adaptin_N PF01602.15 GAP85561.1 - 1.7e-120 402.8 5.2 2e-120 402.6 3.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 GAP85561.1 - 3.9e-46 155.6 0.0 9e-46 154.4 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 GAP85561.1 - 6.8e-19 68.2 0.0 1.2e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain LacAB_rpiB PF02502.13 GAP85562.1 - 0.14 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribose/Galactose Isomerase Membrane_bind PF14564.1 GAP85563.1 - 6.1e-11 42.4 0.0 1.5e-05 25.1 0.0 2.2 1 1 1 2 2 2 2 Membrane binding Crystall_3 PF08964.5 GAP85563.1 - 3.6e-10 39.4 0.0 6e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Beta/Gamma crystallin Crystall PF00030.14 GAP85563.1 - 0.024 14.5 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Beta/Gamma crystallin Methyltransf_23 PF13489.1 GAP85564.1 - 1.4e-09 37.8 0.0 2.1e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP85564.1 - 3.8e-09 36.9 0.0 7.4e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP85564.1 - 4.3e-09 36.7 0.0 9.8e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP85564.1 - 3.6e-06 26.6 0.0 6.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP85564.1 - 0.0067 16.9 0.0 0.024 15.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP85564.1 - 0.056 12.5 0.0 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family P16-Arc PF04699.9 GAP85565.1 - 1.4e-56 190.7 0.0 1.6e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) RNA_pol_3_Rpc31 PF11705.3 GAP85567.1 - 0.0043 17.0 30.9 0.0043 17.0 21.4 1.9 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.9 GAP85567.1 - 0.022 12.8 14.0 0.0062 14.6 6.8 1.9 2 0 0 2 2 2 0 CDC45-like protein Peptidase_S8 PF00082.17 GAP85568.1 - 5e-14 52.1 0.0 1e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Subtilase family Tcf25 PF04910.9 GAP85570.1 - 2.1e-70 237.4 0.0 3.1e-70 236.9 0.0 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 CENP-X PF09415.5 GAP85570.1 - 0.079 12.7 0.1 0.2 11.5 0.1 1.7 1 0 0 1 1 1 0 CENP-S associating Centromere protein X PBP1_TM PF14812.1 GAP85570.1 - 0.15 12.3 0.0 0.15 12.3 0.0 4.5 3 1 1 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 GAP85570.1 - 3.1 7.3 12.3 3.4 7.2 0.1 2.8 2 0 0 2 2 2 0 Sigma-70, non-essential region HMA PF00403.21 GAP85571.1 - 6.5e-14 51.8 0.7 8.6e-14 51.4 0.5 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF211 PF02680.9 GAP85571.1 - 0.12 12.1 0.1 0.2 11.5 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized ArCR, COG1888 Fungal_trans PF04082.13 GAP85572.1 - 2.4e-19 69.2 0.1 4.3e-19 68.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP85572.1 - 5.4e-07 29.4 11.3 1.3e-06 28.1 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CorA PF01544.13 GAP85573.1 - 0.13 11.2 3.1 0.37 9.7 2.1 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Sugar_tr PF00083.19 GAP85574.1 - 1.1e-81 274.6 17.8 1.3e-81 274.4 12.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP85574.1 - 4.5e-13 48.6 33.5 2.9e-12 45.9 23.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAP85574.1 - 0.0045 15.4 19.8 0.021 13.2 3.7 3.1 2 2 1 3 3 3 2 MFS/sugar transport protein Thiolase_C PF02803.13 GAP85577.1 - 6.7e-11 41.6 2.4 8.4e-11 41.3 0.3 2.2 2 1 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 GAP85577.1 - 6.8e-06 25.6 0.1 0.00051 19.6 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 GAP85577.1 - 6.4e-05 22.0 1.0 0.00015 20.8 0.0 2.1 3 0 0 3 3 3 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 GAP85577.1 - 0.0051 16.3 0.1 0.0086 15.5 0.1 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Lin0512_fam PF09585.5 GAP85577.1 - 0.085 12.4 0.2 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein (Lin0512_fam) AAA PF00004.24 GAP85578.1 - 8.3e-50 168.4 0.0 3.2e-38 130.9 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAP85578.1 - 1.3e-08 35.0 0.1 0.001 19.2 0.0 4.0 2 2 0 2 2 2 2 AAA domain AAA_14 PF13173.1 GAP85578.1 - 1.1e-07 31.8 0.0 0.0017 18.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAP85578.1 - 1.4e-07 31.6 0.0 0.0037 17.2 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain Arch_ATPase PF01637.13 GAP85578.1 - 1.6e-07 31.2 0.2 0.036 13.7 0.0 4.1 2 2 2 4 4 4 1 Archaeal ATPase AAA_5 PF07728.9 GAP85578.1 - 2.1e-07 30.7 0.0 0.00089 18.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.12 GAP85578.1 - 3.8e-07 29.6 0.1 6.4e-06 25.7 0.0 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 CDC48_N PF02359.13 GAP85578.1 - 9e-07 28.7 0.0 3.8e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_17 PF13207.1 GAP85578.1 - 1.7e-06 28.8 0.0 0.017 15.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 GAP85578.1 - 1.8e-06 26.9 0.0 0.048 12.3 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_18 PF13238.1 GAP85578.1 - 5.4e-06 26.7 0.0 0.046 14.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_2 PF07724.9 GAP85578.1 - 7.8e-06 25.9 0.0 0.00018 21.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 GAP85578.1 - 2e-05 24.4 0.0 0.26 11.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 GAP85578.1 - 2.7e-05 23.8 0.3 0.021 14.5 0.1 2.7 2 0 0 2 2 2 1 Part of AAA domain RNA_helicase PF00910.17 GAP85578.1 - 0.0002 21.5 0.0 0.2 11.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 GAP85578.1 - 0.00032 19.9 0.3 0.005 16.0 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 GAP85578.1 - 0.00054 19.0 0.0 0.11 11.5 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 GAP85578.1 - 0.00073 18.9 0.2 0.17 11.2 0.0 2.8 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_25 PF13481.1 GAP85578.1 - 0.0039 16.6 1.7 0.58 9.5 0.0 3.2 2 1 0 3 3 3 1 AAA domain NACHT PF05729.7 GAP85578.1 - 0.0059 16.2 1.8 3.2 7.3 0.0 3.4 4 0 0 4 4 3 1 NACHT domain AAA_28 PF13521.1 GAP85578.1 - 0.008 16.1 0.0 3 7.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 GAP85578.1 - 0.0086 15.2 0.1 0.02 14.0 0.1 1.5 1 0 0 1 1 1 1 KaiC AAA_24 PF13479.1 GAP85578.1 - 0.015 14.8 0.2 0.054 13.0 0.1 1.9 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 GAP85578.1 - 0.027 13.9 0.0 1.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.22 GAP85578.1 - 0.055 13.7 0.2 0.55 10.5 0.0 2.3 2 0 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.7 GAP85578.1 - 0.07 12.2 0.1 2.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin PhoH PF02562.11 GAP85578.1 - 0.089 12.0 0.1 3.4 6.8 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein MobB PF03205.9 GAP85578.1 - 0.11 12.2 0.0 20 4.8 0.0 3.0 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Parvo_NS1 PF01057.12 GAP85578.1 - 0.12 11.2 0.1 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 GAP85578.1 - 0.18 11.4 0.0 6.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF2075 PF09848.4 GAP85578.1 - 0.3 10.0 0.0 0.68 8.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 GAP85579.1 - 2.3e-13 50.0 0.0 2.3e-12 46.7 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 GAP85579.1 - 8.4e-08 32.2 0.0 1.1e-06 28.6 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 GAP85579.1 - 1.9e-05 24.4 0.1 4.1e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Defensin_3 PF08131.6 GAP85579.1 - 0.077 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Defensin-like peptide family F-box-like PF12937.2 GAP85580.1 - 0.002 17.7 0.0 0.0077 15.9 0.0 1.9 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 GAP85580.1 - 0.13 11.9 0.1 0.31 10.7 0.1 1.6 1 0 0 1 1 1 0 F-box domain COesterase PF00135.23 GAP85581.1 - 3.3e-98 329.7 0.0 4.4e-98 329.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAP85581.1 - 1.5e-06 27.9 0.1 7.6e-06 25.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold SKG6 PF08693.5 GAP85582.1 - 0.027 13.7 0.2 0.065 12.5 0.2 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM154 PF15102.1 GAP85582.1 - 0.16 11.6 0.6 0.49 10.1 0.0 2.1 2 0 0 2 2 2 0 TMEM154 protein family MFS_1 PF07690.11 GAP85584.1 - 1.6e-12 46.8 27.9 1.6e-12 46.8 19.3 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.8 GAP85584.1 - 2.2e-05 23.8 3.8 7.1e-05 22.1 2.6 1.8 1 1 0 1 1 1 1 Nodulin-like F-box-like PF12937.2 GAP85585.1 - 0.0026 17.4 0.1 0.0048 16.5 0.1 1.4 1 0 0 1 1 1 1 F-box-like Ank_2 PF12796.2 GAP85586.1 - 3.2e-41 139.5 0.0 3.6e-12 46.4 0.0 5.2 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAP85586.1 - 1.1e-38 129.0 8.2 6.9e-09 35.0 0.1 8.8 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.1 GAP85586.1 - 2.7e-31 104.4 9.9 9.8e-05 22.2 0.0 9.9 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.1 GAP85586.1 - 4.2e-28 96.7 11.0 3.8e-06 26.9 0.0 8.9 6 2 4 10 10 10 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAP85586.1 - 9.2e-28 96.1 3.4 6.6e-09 36.0 0.2 6.2 4 2 3 7 7 7 4 Ankyrin repeats (many copies) HET PF06985.6 GAP85586.1 - 6.8e-18 65.1 1.9 1.5e-17 64.0 1.3 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MAPEG PF01124.13 GAP85587.1 - 3.2e-15 55.8 0.8 3.6e-15 55.7 0.5 1.1 1 0 0 1 1 1 1 MAPEG family DUF1634 PF07843.6 GAP85587.1 - 0.06 12.9 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1634) Fungal_trans PF04082.13 GAP85588.1 - 1.9e-15 56.4 1.1 3.5e-15 55.5 0.8 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP85588.1 - 1.1e-06 28.4 7.6 2.3e-06 27.4 5.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cut8_C PF08559.5 GAP85588.1 - 0.035 13.9 0.0 0.091 12.5 0.0 1.6 1 0 0 1 1 1 0 Cut8 six-helix bundle Phosphoesterase PF04185.9 GAP85589.1 - 1.3e-20 73.9 0.5 4.3e-20 72.2 0.3 1.8 1 1 0 1 1 1 1 Phosphoesterase family DUF1115 PF06544.7 GAP85590.1 - 0.00016 21.3 0.0 0.0004 20.0 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1115) DUF2066 PF09839.4 GAP85590.1 - 0.069 12.2 0.0 0.079 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) Glyco_hydro_61 PF03443.9 GAP85591.1 - 8.4e-55 185.9 0.1 1.3e-54 185.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 GAP85591.1 - 5.8e-09 35.4 13.5 5.8e-09 35.4 9.4 3.6 3 1 0 3 3 3 1 Fungal cellulose binding domain Med3 PF11593.3 GAP85591.1 - 3.2 6.8 5.9 5.3 6.1 4.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Tetraspannin PF00335.15 GAP85593.1 - 3.6e-10 39.5 0.0 4.6e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Tetraspanin family Como_LCP PF02247.11 GAP85593.1 - 0.1 11.0 0.3 0.21 9.9 0.2 1.5 1 1 0 1 1 1 0 Large coat protein DUF308 PF03729.8 GAP85594.1 - 0.00091 19.1 10.7 0.00091 19.1 7.4 3.2 3 0 0 3 3 3 2 Short repeat of unknown function (DUF308) An_peroxidase PF03098.10 GAP85595.1 - 2.2e-86 290.3 0.0 3e-84 283.3 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 GAP85595.1 - 1.5e-07 30.3 0.0 2.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 DUF2235 PF09994.4 GAP85596.1 - 2.4e-71 240.3 0.2 2.4e-69 233.8 0.0 2.3 2 1 0 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) Pec_lyase_C PF00544.14 GAP85598.1 - 2.7e-37 128.2 6.1 4.2e-37 127.5 4.2 1.3 1 0 0 1 1 1 1 Pectate lyase PIRT PF15099.1 GAP85598.1 - 1.2 8.3 4.4 0.54 9.4 1.3 1.6 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Zip PF02535.17 GAP85599.1 - 0.89 8.5 11.7 3.1 6.7 8.1 1.9 1 0 0 1 1 1 0 ZIP Zinc transporter BC10 PF06726.7 GAP85600.1 - 1.5e-17 63.3 11.3 2.9e-17 62.4 7.9 1.4 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Cellulase PF00150.13 GAP85601.1 - 3e-08 33.2 0.0 1.3e-06 27.8 0.0 2.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PP2C PF00481.16 GAP85602.1 - 2.5e-42 145.0 0.0 4.9e-42 144.0 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 GAP85602.1 - 0.0001 22.0 0.0 0.16 11.6 0.0 3.1 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 GAP85602.1 - 0.00036 20.0 0.0 0.00067 19.1 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C DUF2014 PF09427.5 GAP85602.1 - 0.058 12.5 0.0 0.088 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) Innate_immun PF12782.2 GAP85604.1 - 0.0017 17.6 6.0 0.0024 17.1 4.2 1.3 1 0 0 1 1 1 1 Invertebrate innate immunity transcript family Zip PF02535.17 GAP85604.1 - 0.1 11.5 4.4 0.12 11.3 3.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 GAP85604.1 - 0.51 9.6 6.8 0.76 9.1 4.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FAD_binding_4 PF01565.18 GAP85605.1 - 8e-17 61.0 1.7 4.1e-16 58.7 1.5 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 GAP85605.1 - 1.3e-13 50.5 1.0 2.6e-13 49.6 0.7 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 GAP85605.1 - 0.026 13.6 0.2 0.041 13.0 0.2 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding adh_short PF00106.20 GAP85607.1 - 1.7e-16 60.6 0.2 2.3e-16 60.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP85607.1 - 3.4e-07 30.1 0.0 5.1e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 GAP85607.1 - 0.00014 22.0 0.0 0.00025 21.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 GAP85607.1 - 0.00029 19.8 0.0 0.00039 19.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 GAP85607.1 - 0.01 15.6 0.4 0.039 13.7 0.2 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.14 GAP85607.1 - 0.011 14.8 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_tran_WecB PF03808.8 GAP85607.1 - 0.054 12.8 0.0 0.49 9.7 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Saccharop_dh PF03435.13 GAP85607.1 - 0.084 11.8 0.5 0.11 11.3 0.4 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase p450 PF00067.17 GAP85608.1 - 1.8e-41 142.1 0.0 2.3e-41 141.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 GAP85609.1 - 1.3e-18 66.8 3.2 3.1e-18 65.5 2.2 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP85609.1 - 1.4e-09 37.6 0.2 3e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.17 GAP85610.1 - 1.6e-48 165.4 0.0 1.9e-48 165.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CorA PF01544.13 GAP85611.1 - 1e-07 31.2 1.8 2e-06 27.0 0.0 2.9 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein Ank_2 PF12796.2 GAP85611.1 - 0.00033 20.9 0.0 0.0032 17.7 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAP85611.1 - 0.0093 16.1 0.7 0.21 11.8 0.1 3.5 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAP85611.1 - 0.044 14.3 0.3 0.95 10.0 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Rab5ip PF07019.7 GAP85611.1 - 0.96 9.6 2.2 2.7 8.1 1.5 1.7 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) ACBP PF00887.14 GAP85612.1 - 2.7e-30 103.8 0.0 5.2e-30 102.9 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein CYTH PF01928.16 GAP85613.1 - 3.9e-06 26.6 1.7 9.9e-06 25.3 0.2 2.2 3 0 0 3 3 3 1 CYTH domain HSBP1 PF06825.7 GAP85613.1 - 0.13 11.8 0.9 1.6 8.3 0.1 2.2 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Radical_SAM PF04055.16 GAP85614.1 - 7.4e-17 62.0 1.5 1e-16 61.5 0.6 1.5 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 GAP85614.1 - 1.3e-07 31.8 0.5 1.3e-07 31.8 0.3 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 GAP85614.1 - 1.6e-07 31.3 0.3 3.4e-07 30.2 0.2 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain ADK PF00406.17 GAP85615.1 - 4.3e-17 62.3 0.0 6.1e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 GAP85615.1 - 1.7e-09 38.5 0.0 2.6e-09 37.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAP85615.1 - 6.9e-09 36.1 0.0 1.6e-08 34.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 GAP85615.1 - 2.6e-06 26.6 0.1 0.0013 17.8 0.0 2.1 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.1 GAP85615.1 - 9.9e-06 25.4 0.3 9e-05 22.3 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAP85615.1 - 0.0015 18.5 0.0 0.0018 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 GAP85615.1 - 0.0021 18.2 0.0 0.0041 17.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAP85615.1 - 0.0022 18.1 0.1 0.0057 16.7 0.0 1.7 1 1 0 2 2 2 1 AAA domain MobB PF03205.9 GAP85615.1 - 0.0039 16.9 0.0 0.0065 16.1 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 GAP85615.1 - 0.0081 15.8 0.1 0.099 12.2 0.1 2.0 1 1 0 1 1 1 1 NACHT domain IstB_IS21 PF01695.12 GAP85615.1 - 0.0093 15.3 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 GAP85615.1 - 0.014 15.1 0.0 0.036 13.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain RNA12 PF10443.4 GAP85615.1 - 0.016 13.7 0.0 0.07 11.6 0.0 1.8 2 0 0 2 2 2 0 RNA12 protein Thymidylate_kin PF02223.12 GAP85615.1 - 0.016 14.6 0.5 2.2 7.5 0.1 2.7 2 1 0 2 2 2 0 Thymidylate kinase ABC_tran PF00005.22 GAP85615.1 - 0.017 15.4 0.0 0.019 15.2 0.0 1.5 1 1 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 GAP85615.1 - 0.027 14.1 0.0 0.04 13.6 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase AAA_10 PF12846.2 GAP85615.1 - 0.029 13.7 0.0 0.042 13.2 0.0 1.3 1 1 0 1 1 1 0 AAA-like domain T2SE PF00437.15 GAP85615.1 - 0.037 12.9 0.0 0.052 12.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 GAP85615.1 - 0.1 11.7 0.0 0.21 10.7 0.0 1.5 2 0 0 2 2 2 0 PhoH-like protein ATP_bind_1 PF03029.12 GAP85615.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Sigma54_activat PF00158.21 GAP85615.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 GAP85615.1 - 0.15 10.8 0.1 0.6 8.9 0.0 1.9 1 1 0 1 1 1 0 NB-ARC domain Ribonuclease_3 PF00636.21 GAP85617.1 - 1.5e-16 60.8 0.6 6.5e-16 58.7 0.0 2.3 3 0 0 3 3 3 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 GAP85617.1 - 9.7e-10 38.5 0.0 2.1e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease-III-like DUF2935 PF11155.3 GAP85617.1 - 0.43 10.6 2.2 21 5.2 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) MRP-S33 PF08293.6 GAP85618.1 - 1e-28 99.1 0.2 1.2e-28 98.8 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 PUF PF00806.14 GAP85619.1 - 5.7e-38 126.2 0.9 8.3e-06 25.0 0.0 8.8 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat Molybdopterin PF00384.17 GAP85620.1 - 4.6e-67 226.6 0.0 3.3e-65 220.5 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 GAP85620.1 - 4.4e-19 68.0 0.1 1.3e-18 66.6 0.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 GAP85620.1 - 1.5e-18 65.7 0.3 4.6e-18 64.1 0.1 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 GAP85620.1 - 6.4e-14 51.8 0.0 1.7e-13 50.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 GAP85620.1 - 8.8e-09 35.0 0.6 8.8e-09 35.0 0.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 GAP85620.1 - 0.047 13.4 0.0 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain HlyU PF10115.4 GAP85620.1 - 0.15 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Transcriptional activator HlyU ketoacyl-synt PF00109.21 GAP85621.1 - 3.2e-76 256.1 3.1 6.3e-76 255.2 0.0 2.8 4 0 0 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAP85621.1 - 5.6e-55 186.9 0.0 1.2e-54 185.8 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 GAP85621.1 - 5.4e-49 166.3 0.0 2.3e-48 164.2 0.0 2.2 2 0 0 2 2 1 1 KR domain PS-DH PF14765.1 GAP85621.1 - 9.8e-41 139.8 0.0 1.7e-40 139.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 GAP85621.1 - 5.8e-39 133.6 0.7 4.2e-38 130.8 0.0 2.8 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAP85621.1 - 1.3e-37 128.2 0.0 6.1e-37 126.0 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 GAP85621.1 - 6e-21 74.3 0.5 1.4e-18 66.6 0.0 3.6 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 GAP85621.1 - 7.6e-20 71.2 0.0 3e-19 69.3 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP85621.1 - 5.5e-16 58.6 0.0 1.5e-15 57.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP85621.1 - 5.1e-11 42.3 0.0 1.9e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP85621.1 - 1.1e-10 41.8 0.0 4e-10 40.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 GAP85621.1 - 1.8e-10 41.8 0.0 3.3e-09 37.7 0.0 3.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Ubie_methyltran PF01209.13 GAP85621.1 - 1.6e-08 33.9 0.0 3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 GAP85621.1 - 2.6e-07 31.1 0.0 1e-06 29.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 GAP85621.1 - 9.8e-07 28.5 0.1 2.1e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 GAP85621.1 - 0.00098 18.1 0.0 0.0021 17.0 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain DREV PF05219.7 GAP85621.1 - 0.002 17.0 0.0 0.0045 15.8 0.0 1.5 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_8 PF05148.10 GAP85621.1 - 0.018 14.6 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase PCMT PF01135.14 GAP85621.1 - 0.038 13.5 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ribonuc_L-PSP PF01042.16 GAP85621.1 - 0.064 13.0 0.2 8.5 6.1 0.0 3.0 3 0 0 3 3 2 0 Endoribonuclease L-PSP PP-binding PF00550.20 GAP85621.1 - 0.084 13.1 0.0 0.26 11.6 0.0 1.9 1 0 0 1 1 1 0 Phosphopantetheine attachment site ILVD_EDD PF00920.16 GAP85622.1 - 1.8e-89 300.5 1.0 1.9e-86 290.6 0.4 2.1 2 0 0 2 2 2 2 Dehydratase family SHOCT PF09851.4 GAP85622.1 - 0.027 13.9 0.2 0.34 10.4 0.0 2.6 2 0 0 2 2 2 0 Short C-terminal domain CENP-F_N PF10481.4 GAP85622.1 - 0.056 12.8 0.1 0.075 12.3 0.1 1.2 1 0 0 1 1 1 0 Cenp-F N-terminal domain XRCC4 PF06632.7 GAP85625.1 - 1.2e-05 24.4 8.0 2.4e-05 23.3 5.5 1.6 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3585 PF12130.3 GAP85625.1 - 0.00033 20.5 2.9 0.00056 19.7 2.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3585) Mnd1 PF03962.10 GAP85625.1 - 0.0022 17.7 1.3 0.0033 17.1 0.9 1.3 1 0 0 1 1 1 1 Mnd1 family ALIX_LYPXL_bnd PF13949.1 GAP85625.1 - 0.037 13.0 4.0 0.059 12.3 2.8 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV FlxA PF14282.1 GAP85625.1 - 0.63 10.0 5.8 0.83 9.6 1.1 2.5 2 0 0 2 2 2 0 FlxA-like protein Aldo_ket_red PF00248.16 GAP85626.1 - 4.9e-43 146.9 0.0 6.4e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.9 GAP85627.1 - 9.6e-118 393.5 0.0 1.2e-117 393.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family PAP2 PF01569.16 GAP85628.1 - 8.3e-18 64.3 3.7 8.3e-18 64.3 2.6 1.7 2 0 0 2 2 2 1 PAP2 superfamily DUF4131 PF13567.1 GAP85628.1 - 5.4 6.3 9.3 13 5.1 2.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Fungal_trans_2 PF11951.3 GAP85629.1 - 6.5e-16 57.9 0.0 8.6e-09 34.4 0.0 3.1 2 1 1 3 3 3 3 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP85629.1 - 1.3e-07 31.3 8.3 3e-07 30.2 5.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 GAP85630.1 - 0.00025 21.0 1.0 0.0034 17.3 0.0 2.2 1 1 1 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 GAP85630.1 - 0.0051 15.7 0.0 0.0075 15.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 GAP85630.1 - 0.081 12.3 0.0 0.13 11.6 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family LigB PF02900.13 GAP85631.1 - 5.2e-44 150.2 0.1 6.2e-44 150.0 0.1 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase His_Phos_1 PF00300.17 GAP85632.1 - 2.2e-10 40.8 0.0 3.9e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AlcCBM31 PF11606.3 GAP85633.1 - 0.043 13.7 0.2 0.094 12.6 0.1 1.5 1 0 0 1 1 1 0 Family 31 carbohydrate binding protein FtsX PF02687.16 GAP85633.1 - 3.2 7.5 11.0 0.85 9.3 1.9 3.1 3 1 1 4 4 4 0 FtsX-like permease family Acetyltransf_7 PF13508.1 GAP85634.1 - 4.9e-06 26.6 0.0 1.1e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAP85634.1 - 0.00052 19.9 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAP85634.1 - 0.00097 18.8 0.0 0.0021 17.7 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 GAP85634.1 - 0.012 15.4 0.0 0.044 13.6 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAP85634.1 - 0.096 12.8 0.0 0.39 10.8 0.0 1.9 1 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Abhydrolase_4 PF08386.5 GAP85635.1 - 8.3e-18 64.1 0.1 2.4e-17 62.7 0.0 1.9 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 GAP85635.1 - 1.3e-16 60.9 0.0 5.1e-16 58.9 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAP85635.1 - 4.5e-05 23.4 0.2 0.00017 21.5 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family SET PF00856.23 GAP85636.1 - 2.1e-06 28.1 0.0 9.3e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 SET domain FeS PF04060.8 GAP85636.1 - 0.024 14.1 2.7 0.057 13.0 1.9 1.6 1 0 0 1 1 1 0 Putative Fe-S cluster Nol1_Nop2_Fmu PF01189.12 GAP85637.1 - 2.3e-89 299.5 0.0 3.2e-89 299.0 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family Blt1 PF12754.2 GAP85638.1 - 2.5e-31 109.4 0.0 6.3e-25 88.4 0.0 2.3 1 1 1 2 2 2 2 Cell-cycle control medial ring component ubiquitin PF00240.18 GAP85638.1 - 0.023 14.1 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family Cofilin_ADF PF00241.15 GAP85639.1 - 2.3e-31 108.3 0.1 2.7e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF1349 PF07081.6 GAP85639.1 - 0.018 14.4 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1349) FYRC PF05965.9 GAP85639.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 F/Y rich C-terminus Cpn60_TCP1 PF00118.19 GAP85640.1 - 2.1e-119 399.3 8.4 2.4e-119 399.1 5.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family adh_short PF00106.20 GAP85641.1 - 5.6e-08 32.8 0.0 1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase DUF922 PF06037.6 GAP85641.1 - 0.13 11.6 0.1 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF922) BPL_LplA_LipB PF03099.14 GAP85643.1 - 2.6e-13 50.0 0.0 1.4e-12 47.6 0.0 2.0 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF3246 PF11596.3 GAP85643.1 - 5.6e-05 22.5 2.2 5.6e-05 22.5 1.5 2.6 4 0 0 4 4 4 1 Protein of unknown function (DUF3246) DUF3439 PF11921.3 GAP85643.1 - 0.27 10.9 5.1 1.2 8.9 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Clathrin PF00637.15 GAP85644.1 - 1.8e-22 79.5 7.3 2.7e-21 75.6 3.3 2.7 3 0 0 3 3 2 1 Region in Clathrin and VPS VPS11_C PF12451.3 GAP85644.1 - 7.9e-15 54.4 0.1 5.6e-14 51.7 0.1 2.4 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-RING_2 PF13639.1 GAP85644.1 - 3.2e-05 23.6 2.6 7.8e-05 22.4 1.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 GAP85644.1 - 0.00054 19.6 1.4 0.0011 18.6 1.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain TPR_12 PF13424.1 GAP85644.1 - 0.00091 19.1 2.2 0.2 11.6 0.0 3.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAP85644.1 - 0.0044 16.6 0.4 0.039 13.6 0.0 2.8 3 0 0 3 3 2 1 TPR repeat zf-Apc11 PF12861.2 GAP85644.1 - 0.0053 16.5 0.9 0.013 15.2 0.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 GAP85644.1 - 0.012 15.7 1.3 0.032 14.3 0.9 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 GAP85644.1 - 0.013 15.5 4.6 0.015 15.2 1.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_14 PF13428.1 GAP85644.1 - 0.013 16.0 0.5 21 6.0 0.0 3.6 3 1 0 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAP85644.1 - 0.055 13.2 2.0 0.2 11.4 0.1 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAP85644.1 - 0.059 13.3 2.2 0.24 11.4 0.0 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat zf-C3HC4 PF00097.20 GAP85644.1 - 0.085 12.5 0.9 0.21 11.2 0.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_19 PF14559.1 GAP85644.1 - 0.17 12.2 1.4 6.7 7.1 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4_4 PF15227.1 GAP85644.1 - 0.23 11.3 2.2 0.5 10.2 1.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DAG1 PF05454.6 GAP85644.1 - 0.96 8.5 3.7 1.6 7.8 2.6 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Prok-RING_1 PF14446.1 GAP85644.1 - 2.4 7.9 4.3 1.5 8.6 0.4 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 HATPase_c_3 PF13589.1 GAP85645.1 - 1.1e-14 54.2 0.0 2.3e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 GAP85645.1 - 2.5e-06 27.1 0.0 7.6e-05 22.3 0.0 2.9 2 1 0 2 2 2 1 MutL C terminal dimerisation domain CN_hydrolase PF00795.17 GAP85647.1 - 1.3e-16 60.4 0.0 1.9e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CFEM PF05730.6 GAP85648.1 - 1e-08 34.8 1.7 2.1e-08 33.8 1.2 1.5 1 0 0 1 1 1 1 CFEM domain Pol_alpha_B_N PF08418.5 GAP85648.1 - 3.6 7.0 7.0 1.3 8.4 3.0 1.6 1 1 1 2 2 2 0 DNA polymerase alpha subunit B N-terminal Ank_2 PF12796.2 GAP85649.1 - 1.7e-11 44.2 0.0 2.6e-06 27.6 0.0 5.6 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAP85649.1 - 4.4e-05 23.0 9.4 0.0022 17.6 0.0 6.9 8 2 0 8 8 8 1 Ankyrin repeat NACHT PF05729.7 GAP85649.1 - 4.9e-05 23.0 0.0 0.00017 21.2 0.0 2.0 1 0 0 1 1 1 1 NACHT domain Ank_4 PF13637.1 GAP85649.1 - 0.00019 21.8 0.0 0.0069 16.8 0.0 3.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP85649.1 - 0.0031 17.5 0.0 1.4 9.3 0.0 4.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 GAP85649.1 - 0.018 15.3 0.0 0.16 12.2 0.0 2.6 1 1 1 2 2 2 0 Ankyrin repeats (many copies) AAA_16 PF13191.1 GAP85649.1 - 0.023 14.7 3.5 0.23 11.4 0.0 3.7 3 0 0 3 3 3 0 AAA ATPase domain KAP_NTPase PF07693.9 GAP85649.1 - 0.27 10.1 4.5 0.9 8.4 0.0 3.3 3 1 1 4 4 4 0 KAP family P-loop domain Ribonuc_red_lgC PF02867.10 GAP85650.1 - 6.9e-221 734.4 0.0 9.8e-221 733.9 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 GAP85650.1 - 1e-23 82.8 0.0 3.6e-23 81.1 0.0 2.0 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 GAP85650.1 - 5.6e-17 61.9 0.1 2.5e-16 59.8 0.0 2.2 2 0 0 2 2 2 1 ATP cone domain NRDD PF13597.1 GAP85650.1 - 0.0069 14.5 0.0 0.012 13.7 0.0 1.2 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase adh_short_C2 PF13561.1 GAP85651.1 - 5.1e-28 98.4 0.8 6.3e-28 98.1 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAP85651.1 - 1.5e-25 90.0 0.3 1.9e-25 89.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP85651.1 - 2.1e-13 50.3 0.2 3e-13 49.8 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAP85651.1 - 0.0016 18.4 0.1 0.0051 16.8 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 GAP85651.1 - 0.031 13.3 0.2 0.062 12.3 0.1 1.6 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 GAP85651.1 - 0.036 13.4 0.1 0.052 12.9 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DRTGG PF07085.7 GAP85651.1 - 0.13 11.9 0.1 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 DRTGG domain TatD_DNase PF01026.16 GAP85652.1 - 7.7e-39 133.4 0.0 2.4e-33 115.4 0.0 2.1 2 0 0 2 2 2 2 TatD related DNase CENP-N PF05238.8 GAP85653.1 - 8.2e-118 393.9 0.0 1.6e-117 392.9 0.0 1.4 1 1 0 1 1 1 1 Kinetochore protein CHL4 like bZIP_2 PF07716.10 GAP85654.1 - 5.8e-11 42.0 10.6 1e-10 41.2 7.3 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 GAP85654.1 - 1.5e-05 24.8 11.0 3.2e-05 23.8 7.6 1.5 1 1 0 1 1 1 1 bZIP transcription factor XhlA PF10779.4 GAP85654.1 - 0.0073 16.2 1.2 0.012 15.5 0.8 1.4 1 0 0 1 1 1 1 Haemolysin XhlA Shugoshin_N PF07558.6 GAP85654.1 - 0.045 13.4 0.4 0.075 12.7 0.3 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region TSC22 PF01166.13 GAP85654.1 - 0.11 12.5 0.5 0.21 11.5 0.3 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family IncA PF04156.9 GAP85654.1 - 2.5 7.6 5.6 3.5 7.1 3.9 1.2 1 0 0 1 1 1 0 IncA protein DUF1289 PF06945.8 GAP85655.1 - 0.17 11.4 0.4 0.26 10.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) HET PF06985.6 GAP85656.1 - 2.7e-25 89.1 0.1 5.2e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WSC PF01822.14 GAP85657.1 - 6.6e-34 115.7 24.7 8.1e-19 67.3 7.5 2.6 2 0 0 2 2 2 2 WSC domain Glyoxal_oxid_N PF07250.6 GAP85657.1 - 4.4e-26 91.4 0.0 2.4e-24 85.7 0.0 3.2 3 1 1 4 4 4 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 GAP85657.1 - 1.4e-23 82.8 0.0 2.8e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) p450 PF00067.17 GAP85658.1 - 5.4e-53 180.1 0.0 6.4e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2235 PF09994.4 GAP85659.1 - 3e-23 82.5 0.1 5.7e-23 81.6 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Miro PF08477.8 GAP85659.1 - 1.6e-07 31.8 0.0 3.6e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 GAP85659.1 - 4.5e-05 23.3 0.0 0.00012 22.0 0.0 1.7 2 0 0 2 2 1 1 50S ribosome-binding GTPase Septin PF00735.13 GAP85659.1 - 0.00039 19.5 0.0 0.00066 18.7 0.0 1.3 1 0 0 1 1 1 1 Septin DUF258 PF03193.11 GAP85659.1 - 0.0015 17.7 0.1 0.0041 16.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Arf PF00025.16 GAP85659.1 - 0.005 16.1 0.2 0.77 8.9 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family AIG1 PF04548.11 GAP85659.1 - 0.013 14.6 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Ras PF00071.17 GAP85659.1 - 0.017 14.4 0.3 0.058 12.7 0.2 1.8 1 1 0 1 1 1 0 Ras family MobB PF03205.9 GAP85659.1 - 0.027 14.1 0.2 0.13 11.9 0.1 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 GAP85659.1 - 0.035 14.4 0.0 0.082 13.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 GAP85659.1 - 0.048 13.8 0.2 0.21 11.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAP85659.1 - 0.051 14.4 0.1 0.16 12.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 GAP85659.1 - 0.063 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 GAP85659.1 - 0.08 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_33 PF13671.1 GAP85659.1 - 0.09 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain IIGP PF05049.8 GAP85659.1 - 0.11 11.2 0.1 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_18 PF13238.1 GAP85659.1 - 0.15 12.3 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.16 GAP85660.1 - 6.3e-11 42.1 0.1 1.4e-06 27.8 0.0 2.6 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 GAP85660.1 - 2.1e-09 37.4 0.0 4.1e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 GAP85660.1 - 4.8e-06 26.2 0.2 1.2e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain UvrD_C PF13361.1 GAP85660.1 - 2.8e-05 23.7 0.0 4.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DEAD PF00270.24 GAP85660.1 - 0.001 18.5 0.0 0.0027 17.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAP85660.1 - 0.0052 16.9 0.0 0.18 11.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain Cas_Cas4 PF01930.12 GAP85660.1 - 0.0066 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.13 GAP85660.1 - 0.019 14.4 0.0 3.6 7.0 0.0 3.3 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.1 GAP85660.1 - 0.023 14.0 0.0 0.064 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 GAP85660.1 - 0.044 13.3 0.2 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 GAP85660.1 - 0.06 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 GAP85660.1 - 0.16 12.1 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.1 GAP85661.1 - 0.12 12.2 0.3 0.18 11.7 0.2 1.2 1 0 0 1 1 1 0 Cytidylate kinase-like family HET PF06985.6 GAP85662.1 - 1.4e-34 119.2 0.2 2.5e-34 118.4 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WW PF00397.21 GAP85662.1 - 0.02 14.7 0.2 0.02 14.7 0.1 2.6 3 0 0 3 3 3 0 WW domain Amidase PF01425.16 GAP85663.1 - 3.2e-34 118.5 0.1 5.9e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Amidase SLAC1 PF03595.12 GAP85664.1 - 1.1e-81 274.1 47.3 1.2e-81 273.9 32.8 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel PAPS_reduct PF01507.14 GAP85665.1 - 3.4e-40 137.7 0.0 5.1e-40 137.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Asp_Glu_race PF01177.17 GAP85666.1 - 6.1e-36 124.3 0.1 7.1e-36 124.1 0.1 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase AP_endonuc_2 PF01261.19 GAP85666.1 - 0.0036 16.6 0.1 0.41 9.9 0.0 2.2 2 0 0 2 2 2 2 Xylose isomerase-like TIM barrel Peripla_BP_1 PF00532.16 GAP85666.1 - 0.063 12.4 0.0 0.22 10.7 0.0 1.7 2 0 0 2 2 2 0 Periplasmic binding proteins and sugar binding domain of LacI family Aminotran_5 PF00266.14 GAP85667.1 - 8.9e-37 126.6 0.0 1.3e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 GAP85667.1 - 0.0012 17.9 0.2 0.0038 16.3 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 GAP85667.1 - 0.0046 15.9 0.1 0.015 14.2 0.0 1.8 3 0 0 3 3 3 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 GAP85667.1 - 0.013 13.8 0.0 0.022 13.0 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Pyr_redox_2 PF07992.9 GAP85668.1 - 1.7e-20 73.7 0.0 2.4e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP85668.1 - 2.4e-07 31.0 0.2 0.012 15.6 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAP85668.1 - 5.2e-07 29.5 0.5 0.0013 18.4 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 GAP85668.1 - 8e-05 21.7 0.1 0.0029 16.5 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 GAP85668.1 - 9.4e-05 21.6 0.1 0.036 13.1 0.0 2.5 3 0 0 3 3 3 2 Thi4 family GIDA PF01134.17 GAP85668.1 - 0.00012 21.1 0.3 0.038 12.8 0.0 2.3 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 GAP85668.1 - 0.00025 20.0 0.4 0.0067 15.3 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 GAP85668.1 - 0.00086 17.8 0.2 0.002 16.6 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 GAP85668.1 - 0.0017 17.3 0.9 0.051 12.4 0.2 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAP85668.1 - 0.0042 16.0 0.4 0.24 10.2 0.4 2.2 1 1 1 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 GAP85668.1 - 0.0051 16.8 0.2 0.011 15.7 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 GAP85668.1 - 0.037 13.0 0.1 0.082 11.9 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.2 GAP85668.1 - 0.074 12.1 1.0 0.17 10.9 0.7 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase Aminotran_1_2 PF00155.16 GAP85670.1 - 8e-19 67.8 0.0 1.3e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II MFS_1 PF07690.11 GAP85671.1 - 2.9e-46 157.8 43.1 2.9e-46 157.8 29.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP85671.1 - 2.8e-16 59.1 12.4 2.8e-16 59.1 8.6 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 GAP85671.1 - 6e-07 28.0 17.4 8.1e-07 27.6 12.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3440 PF11922.3 GAP85671.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) p450 PF00067.17 GAP85672.1 - 1.1e-70 238.4 0.0 1.5e-70 238.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Herpes_UL49_5 PF05702.6 GAP85673.1 - 0.071 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein DUF983 PF06170.7 GAP85673.1 - 0.082 13.0 1.3 0.1 12.7 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF983) Gemin7 PF11095.3 GAP85673.1 - 0.13 11.9 0.1 0.26 11.0 0.0 1.4 2 0 0 2 2 2 0 Gem-associated protein 7 (Gemin7) Ank_2 PF12796.2 GAP85674.1 - 1e-61 205.2 0.3 4.6e-16 58.9 0.2 7.8 3 1 3 9 9 9 7 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAP85674.1 - 3.8e-44 148.3 10.8 4e-09 36.7 0.0 10.8 8 2 2 11 11 11 8 Ankyrin repeats (many copies) Ank PF00023.25 GAP85674.1 - 8.9e-40 132.5 30.0 3.2e-07 29.8 0.2 15.0 15 2 1 16 16 16 8 Ankyrin repeat Ank_3 PF13606.1 GAP85674.1 - 2.2e-31 104.7 10.9 0.0017 18.4 0.0 12.9 14 0 0 14 14 14 8 Ankyrin repeat Ank_5 PF13857.1 GAP85674.1 - 6e-30 102.5 16.3 3.3e-08 33.5 0.3 9.9 9 2 2 11 11 11 6 Ankyrin repeats (many copies) Pkinase PF00069.20 GAP85675.1 - 7.6e-53 179.3 0.3 1.3e-37 129.3 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAP85675.1 - 4.2e-23 81.7 0.0 5.6e-12 45.2 0.0 3.4 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 GAP85675.1 - 3.9e-06 26.7 0.3 0.0022 17.7 0.0 2.9 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 GAP85675.1 - 5.1e-06 25.6 0.0 1.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like SRP19 PF01922.12 GAP85676.1 - 1.2e-25 89.9 0.0 1.9e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein Baculo_PP31 PF05311.6 GAP85676.1 - 0.36 10.0 1.4 0.46 9.7 1.0 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Suf PF05843.9 GAP85676.1 - 1.1 8.9 4.4 1.6 8.3 3.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.8 GAP85676.1 - 1.5 8.8 7.9 2.5 8.1 5.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Dynactin PF12455.3 GAP85677.1 - 4.2e-85 284.9 10.1 4.2e-85 284.9 7.0 3.5 5 0 0 5 5 5 1 Dynein associated protein CAP_GLY PF01302.20 GAP85677.1 - 2.5e-21 75.1 0.2 4.1e-21 74.4 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF3138 PF11336.3 GAP85677.1 - 3.2 5.8 15.3 0.11 10.6 5.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) p450 PF00067.17 GAP85678.1 - 8e-63 212.5 0.0 7.7e-42 143.3 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Methyltransf_2 PF00891.13 GAP85678.1 - 6.3e-33 113.9 0.0 1e-32 113.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase GST_N PF02798.15 GAP85678.1 - 5e-05 23.3 0.1 0.00063 19.8 0.0 2.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAP85678.1 - 0.00027 20.8 0.0 0.0014 18.5 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAP85678.1 - 0.0034 17.2 0.0 0.0096 15.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAP85678.1 - 0.0038 17.6 0.0 0.013 15.9 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Methyltransf_23 PF13489.1 GAP85678.1 - 0.0038 16.9 0.1 0.33 10.6 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain GST_C PF00043.20 GAP85678.1 - 0.011 15.7 0.0 0.027 14.4 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ApoLp-III PF07464.6 GAP85678.1 - 0.083 12.9 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) IF2_N PF04760.10 GAP85678.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region MBOAT_2 PF13813.1 GAP85679.1 - 2.1e-17 62.9 3.7 6.1e-17 61.4 2.5 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Pyr_redox_2 PF07992.9 GAP85679.1 - 7.9e-12 45.4 0.0 1.2e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP85679.1 - 0.00061 19.9 0.0 0.4 10.6 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAP85679.1 - 0.015 13.7 0.0 2.5 6.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.1 GAP85679.1 - 0.021 14.8 0.0 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAP85679.1 - 0.041 12.7 0.0 0.065 12.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 GAP85679.1 - 0.053 12.5 0.0 0.081 11.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 GAP85679.1 - 0.064 12.1 0.0 0.099 11.4 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DAO PF01266.19 GAP85679.1 - 0.073 11.9 1.1 0.27 10.0 0.1 2.0 1 1 0 2 2 2 0 FAD dependent oxidoreductase HMG_box PF00505.14 GAP85680.1 - 1.8e-20 72.9 0.8 3.4e-20 72.0 0.6 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 GAP85680.1 - 5.3e-06 26.7 0.4 1.1e-05 25.6 0.2 1.5 1 0 0 1 1 1 1 HMG-box domain TIP49 PF06068.8 GAP85681.1 - 1e-185 617.1 0.2 1.2e-185 616.9 0.2 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 GAP85681.1 - 7.2e-11 42.4 0.2 1.7e-06 28.2 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 GAP85681.1 - 3e-10 39.5 0.6 2.4e-06 26.7 0.0 3.1 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 GAP85681.1 - 1.3e-05 25.3 0.4 0.08 13.0 0.1 2.6 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 GAP85681.1 - 3.2e-05 23.9 0.0 0.0047 16.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 GAP85681.1 - 5e-05 22.9 0.2 0.00014 21.4 0.2 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 GAP85681.1 - 5.4e-05 23.2 0.1 0.00013 22.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 GAP85681.1 - 0.002 17.8 0.2 0.04 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 GAP85681.1 - 0.0052 16.2 0.1 0.012 15.0 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 GAP85681.1 - 0.0057 16.0 0.0 0.026 13.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 GAP85681.1 - 0.0064 15.5 0.0 0.017 14.0 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 GAP85681.1 - 0.0076 16.5 0.1 0.021 15.1 0.1 1.9 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 GAP85681.1 - 0.012 14.7 0.2 0.24 10.5 0.1 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 GAP85681.1 - 0.026 13.9 0.2 1.8 8.0 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_17 PF13207.1 GAP85681.1 - 0.033 15.0 0.1 0.082 13.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 GAP85681.1 - 0.081 12.0 0.2 0.24 10.4 0.1 1.7 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 GAP85681.1 - 0.11 12.5 0.0 2.1 8.3 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_33 PF13671.1 GAP85681.1 - 0.14 12.0 0.1 0.82 9.5 0.0 2.2 2 1 1 3 3 3 0 AAA domain EamA PF00892.15 GAP85682.1 - 1e-17 64.3 26.8 1.1e-11 44.8 1.3 3.6 2 2 2 4 4 4 2 EamA-like transporter family EmrE PF13536.1 GAP85682.1 - 0.00051 20.2 3.9 0.00051 20.2 2.7 3.4 2 2 2 4 4 4 1 Multidrug resistance efflux transporter TFIID-18kDa PF02269.11 GAP85683.1 - 4.1e-21 74.5 0.1 9.4e-21 73.4 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-S PF15630.1 GAP85683.1 - 0.012 15.8 0.0 0.035 14.2 0.0 1.8 1 0 0 1 1 1 0 Kinetochore component CENP-S TAF PF02969.12 GAP85683.1 - 0.034 14.0 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 GAP85683.1 - 0.044 13.5 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated MMtag PF10159.4 GAP85683.1 - 0.049 13.6 0.2 0.088 12.8 0.2 1.3 1 0 0 1 1 1 0 Kinase phosphorylation protein Histone PF00125.19 GAP85683.1 - 0.064 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF4051 PF13260.1 GAP85683.1 - 0.78 9.1 3.1 0.53 9.6 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) DUF1242 PF06842.7 GAP85684.1 - 4.2e-19 67.7 1.0 5.6e-19 67.3 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DUF3317 PF11779.3 GAP85684.1 - 0.067 12.6 1.0 0.067 12.6 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3317) Bac_export_2 PF01312.14 GAP85684.1 - 0.28 10.0 1.1 0.3 9.9 0.8 1.0 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Tcp11 PF05794.8 GAP85685.1 - 1.4e-77 261.3 0.4 1.6e-73 247.9 1.1 2.1 2 0 0 2 2 2 2 T-complex protein 11 Exo_endo_phos PF03372.18 GAP85686.1 - 6.9e-13 49.0 0.4 1.1e-12 48.4 0.3 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Uds1 PF15456.1 GAP85687.1 - 5.4e-42 142.6 6.9 5.4e-42 142.6 4.8 7.7 5 2 3 8 8 8 1 Up-regulated During Septation APG6 PF04111.7 GAP85687.1 - 0.0009 18.3 3.8 0.0009 18.3 2.6 6.4 4 2 2 6 6 6 3 Autophagy protein Apg6 Tropomyosin_1 PF12718.2 GAP85687.1 - 0.0065 16.3 2.9 0.0065 16.3 2.0 8.2 4 2 4 8 8 8 3 Tropomyosin like DUF1751 PF08551.5 GAP85688.1 - 0.00061 20.0 0.9 0.0012 19.1 0.6 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Transgly_assoc PF04226.8 GAP85688.1 - 0.13 12.3 6.0 12 6.0 0.0 3.4 3 0 0 3 3 3 0 Transglycosylase associated protein Tic20 PF09685.5 GAP85688.1 - 6.6 6.7 8.3 7.2 6.6 2.9 2.6 2 1 0 2 2 2 0 Tic20-like protein Prenyltransf PF01255.14 GAP85689.1 - 3.5e-86 287.9 0.0 7.2e-86 286.9 0.0 1.4 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase PHD PF00628.24 GAP85690.1 - 8.2e-10 38.2 7.9 1.4e-09 37.5 5.5 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 GAP85690.1 - 3.7e-06 27.1 0.1 9.1e-05 22.6 0.1 2.4 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding LRR_6 PF13516.1 GAP85691.1 - 2.8e-05 23.7 0.2 0.041 13.9 0.0 4.3 3 0 0 3 3 3 1 Leucine Rich repeat LRR_4 PF12799.2 GAP85691.1 - 0.00092 18.7 2.2 0.12 11.9 0.0 4.1 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAP85691.1 - 0.016 14.9 3.8 0.19 11.5 0.0 3.8 4 0 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.28 GAP85691.1 - 0.17 12.0 5.2 21 5.6 0.0 5.5 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 GAP85691.1 - 0.37 11.1 6.6 16 6.2 0.0 5.8 6 0 0 6 6 6 0 Leucine rich repeat TauD PF02668.11 GAP85692.1 - 1.7e-37 129.5 0.4 2.2e-37 129.1 0.3 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Zn_clus PF00172.13 GAP85693.1 - 3.1e-07 30.1 13.2 5.2e-07 29.4 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAP85693.1 - 0.00011 21.1 0.1 0.00019 20.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain GCM PF03615.10 GAP85693.1 - 0.13 11.8 2.9 0.37 10.3 1.9 1.8 2 0 0 2 2 2 0 GCM motif protein DUF2368 PF10166.4 GAP85693.1 - 0.16 11.5 0.2 0.32 10.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) OMPdecase PF00215.19 GAP85694.1 - 6.8e-92 306.9 0.0 8e-92 306.7 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family CDP-OH_P_transf PF01066.16 GAP85695.1 - 1.3e-18 67.1 4.8 1.3e-18 67.1 3.3 1.7 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase AA_permease_2 PF13520.1 GAP85697.1 - 1.6e-46 158.7 47.4 1.9e-46 158.5 32.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAP85697.1 - 1.4e-28 99.4 34.7 1.4e-28 99.4 24.0 2.0 1 1 1 2 2 2 2 Amino acid permease Peptidase_S10 PF00450.17 GAP85700.1 - 1.3e-74 251.8 0.0 3.4e-74 250.4 0.0 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase DUF3632 PF12311.3 GAP85702.1 - 7.1e-32 110.6 0.6 1.2e-31 109.9 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Ank_2 PF12796.2 GAP85703.1 - 9.3e-18 64.3 3.9 2.4e-09 37.4 0.1 2.9 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAP85703.1 - 3.3e-12 46.2 0.6 3.4e-08 33.4 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 GAP85703.1 - 4.9e-10 38.6 0.1 2.4e-06 27.0 0.2 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 GAP85703.1 - 1.2e-08 35.1 1.3 0.00014 22.2 0.0 5.3 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP85703.1 - 1.4e-06 27.9 1.0 8.4e-05 22.4 0.1 4.1 5 0 0 5 5 5 1 Ankyrin repeat Frataxin_Cyay PF01491.11 GAP85705.1 - 4.7e-34 116.4 0.1 6.1e-34 116.1 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Gp_dh_C PF02800.15 GAP85706.1 - 9.1e-76 252.6 0.0 1.3e-75 252.1 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 GAP85706.1 - 1.4e-59 200.4 0.1 2.3e-59 199.6 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 GAP85706.1 - 0.0021 17.9 0.9 0.012 15.5 0.1 2.5 2 1 1 3 3 3 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 GAP85706.1 - 0.077 12.1 0.0 0.19 10.8 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TIP49 PF06068.8 GAP85707.1 - 3.9e-174 579.0 3.8 4.6e-174 578.8 2.6 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 GAP85707.1 - 8.5e-09 34.8 2.4 4.7e-05 22.5 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 GAP85707.1 - 3.8e-08 33.5 2.0 3.5e-05 24.0 0.0 3.1 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.10 GAP85707.1 - 1.6e-06 27.2 0.5 2.7e-06 26.4 0.4 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 GAP85707.1 - 1.1e-05 25.5 0.1 0.025 14.6 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 GAP85707.1 - 5.4e-05 23.2 0.1 0.0073 16.3 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.16 GAP85707.1 - 0.00028 20.1 0.5 0.0056 15.8 0.3 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 GAP85707.1 - 0.00055 19.8 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 GAP85707.1 - 0.0076 15.7 0.0 4.6 6.6 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.1 GAP85707.1 - 0.025 14.3 0.8 0.083 12.6 0.3 2.1 1 1 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 GAP85707.1 - 0.027 13.8 0.1 0.053 12.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 GAP85707.1 - 0.05 13.5 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAP85707.1 - 0.068 13.4 0.0 0.5 10.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 GAP85707.1 - 0.089 12.5 0.1 3.2 7.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 GAP85707.1 - 0.097 12.2 0.1 0.14 11.6 0.1 1.4 1 1 0 1 1 1 0 AAA domain TMF_DNA_bd PF12329.3 GAP85708.1 - 0.0074 16.0 6.5 0.0074 16.0 4.5 6.4 5 2 0 6 6 6 1 TATA element modulatory factor 1 DNA binding HALZ PF02183.13 GAP85708.1 - 0.0093 15.6 4.3 0.066 12.9 0.6 3.3 2 1 1 3 3 3 1 Homeobox associated leucine zipper Baculo_PEP_C PF04513.7 GAP85708.1 - 0.021 14.6 27.2 0.45 10.3 1.1 4.0 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus CagZ PF09053.5 GAP85708.1 - 0.029 13.7 3.5 0.077 12.3 2.4 1.7 1 0 0 1 1 1 0 CagZ DUF1664 PF07889.7 GAP85708.1 - 0.22 11.2 21.8 0.73 9.6 0.2 5.1 1 1 2 5 5 5 0 Protein of unknown function (DUF1664) Nup54 PF13874.1 GAP85708.1 - 1.6 8.4 17.6 0.12 12.0 4.8 3.6 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 NPV_P10 PF05531.7 GAP85708.1 - 1.7 8.9 23.4 1.8 8.8 1.2 6.5 2 2 3 5 5 5 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.6 GAP85708.1 - 2.6 8.0 13.0 13 5.8 0.1 5.5 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) Lumazine_bd PF12870.2 GAP85708.1 - 3.7 7.6 11.2 0.3 11.1 0.8 3.1 3 0 0 3 3 3 0 Lumazine-binding domain Reo_sigmaC PF04582.7 GAP85708.1 - 4.9 6.2 17.0 0.99 8.5 5.2 3.1 1 1 1 3 3 3 0 Reovirus sigma C capsid protein PTH2 PF01981.11 GAP85709.1 - 6e-42 141.9 0.3 4.1e-37 126.4 0.1 2.2 2 0 0 2 2 2 2 Peptidyl-tRNA hydrolase PTH2 GYF PF02213.11 GAP85711.1 - 1.1e-10 40.9 1.7 2e-10 40.0 1.2 1.5 1 0 0 1 1 1 1 GYF domain UFD1 PF03152.9 GAP85712.1 - 1.4e-67 226.2 0.0 1.8e-67 225.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 DUF4646 PF15496.1 GAP85713.1 - 0.1 12.6 0.0 14 5.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4646) Myb_DNA-bind_4 PF13837.1 GAP85714.1 - 0.083 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain HET PF06985.6 GAP85716.1 - 1e-18 67.8 2.5 4.1e-17 62.6 1.7 2.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Het-C PF07217.6 GAP85717.1 - 1.2e-148 495.9 0.0 1.5e-148 495.6 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C FTZ PF03867.9 GAP85717.1 - 0.073 12.3 0.1 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Dynactin_p62 PF05502.8 GAP85719.1 - 9.1 4.9 7.1 13 4.3 4.9 1.2 1 0 0 1 1 1 0 Dynactin p62 family HET PF06985.6 GAP85721.1 - 0.00049 20.2 0.0 0.00082 19.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Phage_lysozyme PF00959.14 GAP85722.1 - 2.2e-13 50.4 0.0 3.2e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Phage lysozyme DUF2342 PF10103.4 GAP85723.1 - 0.083 11.8 0.0 0.092 11.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2342) Cu_amine_oxid PF01179.15 GAP85724.1 - 7.1e-157 522.3 0.0 8.6e-157 522.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 GAP85724.1 - 6e-11 42.2 0.0 1.1e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 GAP85724.1 - 1.8e-07 31.1 0.0 5.9e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain adh_short PF00106.20 GAP85725.1 - 3.1e-37 128.0 4.1 4.4e-37 127.5 2.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP85725.1 - 9.1e-32 110.7 0.2 1.1e-31 110.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP85725.1 - 4.8e-19 68.7 1.7 6.3e-19 68.3 1.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAP85725.1 - 7.3e-08 32.1 0.5 1.8e-07 30.8 0.3 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 GAP85725.1 - 0.0003 19.8 0.6 0.00055 19.0 0.4 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 GAP85725.1 - 0.013 15.2 1.3 0.025 14.3 0.2 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Fungal_trans_2 PF11951.3 GAP85726.1 - 4.5e-51 173.6 1.1 5.4e-51 173.3 0.8 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain AA_permease_2 PF13520.1 GAP85727.1 - 6e-53 179.9 47.6 7.4e-53 179.6 33.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAP85727.1 - 6e-22 77.6 38.4 8.7e-22 77.0 26.6 1.1 1 0 0 1 1 1 1 Amino acid permease Abhydrolase_3 PF07859.8 GAP85728.1 - 2e-45 154.9 0.0 2.4e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 GAP85728.1 - 2.4e-06 26.5 0.9 4.9e-06 25.5 0.6 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 GAP85728.1 - 0.0095 15.6 0.1 0.012 15.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP85728.1 - 0.074 12.9 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase_phd PF10503.4 GAP85728.1 - 0.093 11.9 0.0 0.87 8.7 0.0 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase Amino_oxidase PF01593.19 GAP85729.1 - 1.2e-42 146.5 0.1 1.5e-42 146.2 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 GAP85729.1 - 1e-14 54.2 0.3 3.4e-07 29.4 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAP85729.1 - 7.9e-14 51.4 0.6 4.9e-13 48.9 0.3 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 GAP85729.1 - 6.5e-06 25.4 0.0 1.2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAP85729.1 - 6.5e-06 25.2 1.7 1.2e-05 24.3 1.2 1.6 1 1 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 GAP85729.1 - 2.2e-05 23.6 0.0 0.0011 18.0 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 GAP85729.1 - 0.00014 21.0 0.2 0.00028 20.0 0.2 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 GAP85729.1 - 0.00024 19.7 0.1 0.0014 17.1 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 GAP85729.1 - 0.00032 20.8 0.2 0.026 14.6 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAP85729.1 - 0.00044 20.5 1.0 0.0028 18.0 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAP85729.1 - 0.0021 16.9 0.0 0.0049 15.7 0.0 1.6 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 GAP85729.1 - 0.0034 17.3 0.1 0.0083 16.0 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Autoind_bind PF03472.10 GAP85729.1 - 0.028 13.7 0.0 0.56 9.4 0.0 2.5 2 1 0 2 2 2 0 Autoinducer binding domain Lycopene_cycl PF05834.7 GAP85729.1 - 0.19 10.6 1.0 0.21 10.4 0.1 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Mac PF12464.3 GAP85730.1 - 9.6e-15 54.3 0.0 2e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.1 GAP85730.1 - 1.4e-11 43.7 4.1 1.1e-08 34.5 0.5 2.5 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 GAP85730.1 - 2.2e-11 42.6 3.6 4.2e-08 32.3 0.8 2.8 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Acetyltransf_11 PF13720.1 GAP85730.1 - 0.12 12.5 0.1 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 CDC37_N PF03234.9 GAP85732.1 - 4.2e-29 102.1 0.0 1e-28 100.8 0.0 1.7 1 0 0 1 1 1 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 GAP85732.1 - 7e-21 74.4 0.0 1.3e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 GAP85732.1 - 4.3e-20 71.4 0.1 1.2e-19 70.0 0.0 1.7 1 0 0 1 1 1 1 Cdc37 C terminal domain HET PF06985.6 GAP85733.1 - 7.1e-23 81.3 0.2 3.5e-22 79.0 0.1 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA_33 PF13671.1 GAP85734.1 - 5.5e-09 36.0 0.0 6.8e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAP85734.1 - 5.4e-07 29.9 0.0 1.1e-06 29.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAP85734.1 - 4.5e-05 24.2 0.0 5.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 GAP85734.1 - 0.0024 17.8 0.0 0.0026 17.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 GAP85734.1 - 0.011 15.9 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 GAP85734.1 - 0.015 14.4 0.0 0.051 12.6 0.0 1.8 1 1 0 1 1 1 0 Zeta toxin RuvB_N PF05496.7 GAP85734.1 - 0.027 13.5 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 GAP85734.1 - 0.044 13.9 0.0 0.054 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cytomega_UL20A PF05984.7 GAP85735.1 - 0.014 15.5 0.2 0.028 14.6 0.1 1.5 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein Imm35 PF15581.1 GAP85735.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 35 HsbA PF12296.3 GAP85735.1 - 0.29 10.9 12.9 0.14 12.0 4.7 2.2 1 1 1 2 2 2 0 Hydrophobic surface binding protein A Baculo_PEP_C PF04513.7 GAP85735.1 - 0.87 9.4 17.7 0.66 9.8 8.8 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FAA_hydrolase PF01557.13 GAP85736.1 - 1.6e-29 102.8 0.0 2.6e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family RRM_1 PF00076.17 GAP85737.1 - 2e-44 149.0 0.0 5.7e-16 57.9 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP85737.1 - 3.9e-35 119.6 0.0 5.8e-11 42.2 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP85737.1 - 2.4e-18 65.7 0.0 7.3e-08 32.1 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAP85737.1 - 1.8e-10 40.4 0.0 0.0033 17.1 0.0 3.9 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 GAP85737.1 - 0.32 10.8 4.0 1.9 8.4 0.0 3.3 3 0 0 3 3 3 0 RNA binding motif HA2 PF04408.18 GAP85738.1 - 1.7e-18 66.5 0.1 1.7e-18 66.5 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 GAP85738.1 - 2.8e-13 49.5 0.1 6.3e-13 48.4 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAP85738.1 - 8.1e-10 38.4 0.0 1.9e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 GAP85738.1 - 3e-08 33.4 0.0 6.8e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 GAP85738.1 - 3.1e-07 30.5 0.1 3.1e-07 30.5 0.1 2.8 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.1 GAP85738.1 - 0.017 14.6 0.0 0.05 13.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 GAP85738.1 - 0.043 14.1 0.2 0.22 11.8 0.0 2.3 2 0 0 2 2 2 0 ABC transporter DUF3554 PF12074.3 GAP85739.1 - 8.4e-80 268.7 0.6 9.2e-79 265.3 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3554) HEAT PF02985.17 GAP85739.1 - 9.1e-36 118.7 39.5 0.099 12.7 0.0 24.7 26 0 0 26 26 25 9 HEAT repeat HEAT_2 PF13646.1 GAP85739.1 - 9.4e-34 115.5 61.1 1.1e-08 35.2 0.1 17.7 12 6 5 17 17 17 10 HEAT repeats HEAT_EZ PF13513.1 GAP85739.1 - 2.7e-31 107.2 63.8 0.0006 20.2 0.0 24.4 18 5 10 28 28 26 10 HEAT-like repeat Vac14_Fab1_bd PF12755.2 GAP85739.1 - 9.4e-15 54.7 0.0 0.62 10.4 0.0 9.7 7 2 1 8 8 8 2 Vacuolar 14 Fab1-binding region ParcG PF10274.4 GAP85739.1 - 8.6e-10 38.8 1.5 0.00096 19.1 0.0 5.7 5 0 0 5 5 5 2 Parkin co-regulated protein Cnd1 PF12717.2 GAP85739.1 - 1.2e-09 38.2 0.0 5.8 6.7 0.1 8.0 5 2 3 8 8 7 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 GAP85739.1 - 3.5e-09 36.3 0.0 0.012 14.9 0.0 6.0 4 1 1 6 6 6 2 CLASP N terminal UME PF08064.8 GAP85739.1 - 1.1e-05 25.2 0.0 14 5.6 0.0 7.0 6 1 1 7 7 7 0 UME (NUC010) domain Ipi1_N PF12333.3 GAP85739.1 - 3.1e-05 23.8 0.4 0.022 14.7 0.0 5.2 4 0 0 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation DUF2454 PF10521.4 GAP85739.1 - 0.0025 16.8 0.1 8.7 5.2 0.0 4.7 4 1 1 5 5 5 1 Protein of unknown function (DUF2454) AAA_10 PF12846.2 GAP85739.1 - 0.07 12.5 3.3 2.9 7.2 0.3 4.0 2 1 0 3 3 3 0 AAA-like domain MMS19_C PF12460.3 GAP85739.1 - 0.1 11.3 10.1 0.52 8.9 0.2 5.7 5 1 1 6 6 6 0 RNAPII transcription regulator C-terminal HEAT_PBS PF03130.11 GAP85739.1 - 0.23 12.0 15.3 43 5.0 0.1 8.4 7 0 0 7 7 6 0 PBS lyase HEAT-like repeat DUF3896 PF13035.1 GAP85739.1 - 7.9 6.6 5.3 18 5.4 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) Ribosomal_L19e PF01280.15 GAP85740.1 - 1.2e-60 203.5 8.2 1.2e-60 203.5 5.7 2.0 1 1 1 2 2 2 1 Ribosomal protein L19e RNase_H2-Ydr279 PF09468.5 GAP85740.1 - 0.059 12.5 1.1 0.059 12.5 0.7 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) TRAP-gamma PF07074.7 GAP85740.1 - 0.95 8.9 5.7 1.5 8.3 4.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) SHMT PF00464.14 GAP85741.1 - 3.9e-196 651.1 0.0 4.6e-196 650.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 GAP85741.1 - 0.025 13.7 0.0 0.043 12.9 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase Hydrolase_6 PF13344.1 GAP85742.1 - 8.9e-24 83.3 0.0 1.5e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAP85742.1 - 4.1e-13 48.8 0.0 3.6e-12 45.8 0.0 2.4 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 GAP85742.1 - 0.0047 17.1 0.0 3.9 7.6 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase adh_short PF00106.20 GAP85743.1 - 1.9e-26 93.0 8.2 2.3e-26 92.6 5.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP85743.1 - 7e-19 68.5 0.0 8.5e-19 68.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP85743.1 - 3.4e-11 43.1 4.1 4.8e-11 42.6 2.8 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAP85743.1 - 1.1 9.2 4.3 4 7.4 3.0 1.9 1 1 0 1 1 1 0 NADH(P)-binding MR_MLE_C PF13378.1 GAP85744.1 - 4.6e-21 74.8 0.0 8.9e-21 73.9 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 GAP85744.1 - 1.3e-12 48.0 0.0 3e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 GAP85744.1 - 1.9e-10 40.7 0.0 3.4e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Glyco_hydro_42 PF02449.10 GAP85744.1 - 0.12 11.5 0.0 0.24 10.4 0.0 1.4 2 0 0 2 2 2 0 Beta-galactosidase Fungal_trans PF04082.13 GAP85745.1 - 2.3e-24 85.6 0.7 3.5e-24 85.0 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP85745.1 - 9.5e-09 35.0 13.0 1.5e-08 34.3 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CFEM PF05730.6 GAP85747.1 - 2.3e-08 33.7 7.3 6.2e-08 32.3 5.0 1.7 1 0 0 1 1 1 1 CFEM domain Herpes_gE PF02480.11 GAP85747.1 - 0.00028 19.3 0.4 0.00071 17.9 0.3 1.6 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 GAP85747.1 - 0.024 13.9 0.4 0.11 11.8 0.3 2.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FAM176 PF14851.1 GAP85747.1 - 0.034 13.8 1.0 0.063 12.9 0.0 1.8 1 1 1 2 2 2 0 FAM176 family EphA2_TM PF14575.1 GAP85747.1 - 0.045 14.1 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF347 PF03988.7 GAP85747.1 - 0.13 12.1 0.4 0.13 12.1 0.3 1.8 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) Ribosomal_L22 PF00237.14 GAP85748.1 - 4e-13 49.2 0.8 1.2e-10 41.3 0.5 2.7 1 1 0 1 1 1 1 Ribosomal protein L22p/L17e Exonuc_VII_L PF02601.10 GAP85748.1 - 0.07 12.3 1.9 0.12 11.5 1.3 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mitochondr_Som1 PF11093.3 GAP85749.1 - 5.4e-12 45.3 0.0 6.6e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 FAR1 PF03101.10 GAP85751.1 - 1.4e-07 31.9 0.0 1.4e-07 31.9 0.0 2.9 2 1 0 2 2 2 1 FAR1 DNA-binding domain Mem_trans PF03547.13 GAP85751.1 - 0.25 9.6 0.8 0.31 9.2 0.6 1.4 1 0 0 1 1 1 0 Membrane transport protein HTH_24 PF13412.1 GAP85751.1 - 1.1 8.7 3.0 0.84 9.0 0.2 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 GAP85751.1 - 9.1 5.9 9.5 0.18 11.4 0.3 2.7 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain Isochorismatase PF00857.15 GAP85752.1 - 3.5e-26 92.1 0.0 9.4e-26 90.7 0.0 1.7 1 1 0 1 1 1 1 Isochorismatase family 2OG-FeII_Oxy_2 PF13532.1 GAP85752.1 - 7.4e-22 78.1 0.0 7.4e-22 78.1 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily GST_C_2 PF13410.1 GAP85752.1 - 0.0075 16.1 0.4 0.049 13.5 0.3 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAP85752.1 - 0.038 14.4 0.1 0.22 11.9 0.0 2.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PAT1 PF09770.4 GAP85752.1 - 0.98 7.5 18.3 1.6 6.8 12.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Bromo_TP PF07524.8 GAP85754.1 - 5.3e-13 48.4 0.0 1.2e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.4 GAP85754.1 - 1.8e-10 40.6 2.3 1.8e-10 40.6 1.6 2.2 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term GlutR_dimer PF00745.15 GAP85754.1 - 0.079 12.9 3.8 0.68 9.9 2.6 2.1 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain WD40 PF00400.27 GAP85755.1 - 1.2e-61 202.4 24.9 1.2e-11 43.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 GAP85755.1 - 1.6e-05 23.2 8.6 0.41 8.7 0.7 4.2 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 GAP85755.1 - 0.018 13.3 0.1 3.5 5.8 0.1 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain mRNA_stabil PF13929.1 GAP85755.1 - 0.1 11.5 0.1 0.34 9.8 0.0 1.7 2 0 0 2 2 2 0 mRNA stabilisation RNA_pol_Rpb2_6 PF00562.23 GAP85756.1 - 1e-124 416.2 0.1 2.3e-124 415.0 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 GAP85756.1 - 8.5e-54 181.5 0.0 1.4e-53 180.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 GAP85756.1 - 1.9e-46 157.9 0.1 3.7e-46 156.9 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 GAP85756.1 - 2.5e-30 104.5 0.0 7.1e-30 103.1 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 GAP85756.1 - 5.5e-24 83.8 0.1 1.4e-23 82.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 GAP85756.1 - 2.1e-22 78.6 0.1 5e-22 77.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 GAP85756.1 - 9.9e-21 73.3 0.1 3.2e-20 71.7 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 DUF2235 PF09994.4 GAP85757.1 - 2.1e-99 332.4 0.4 2.9e-99 331.9 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) An_peroxidase PF03098.10 GAP85759.1 - 4.3e-98 329.0 0.0 6.9e-96 321.7 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 GAP85759.1 - 0.065 11.7 0.0 0.25 9.7 0.0 1.8 2 0 0 2 2 2 0 Cytochrome P450 E1-E2_ATPase PF00122.15 GAP85760.1 - 1.3e-52 178.1 0.3 3.1e-52 176.8 0.2 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAP85760.1 - 2.2e-36 125.0 5.2 2.2e-36 125.0 3.6 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAP85760.1 - 1.6e-32 113.6 0.0 2.7e-31 109.6 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAP85760.1 - 9.7e-16 57.5 0.0 2.7e-15 56.0 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 GAP85760.1 - 1.9e-14 54.2 0.1 8.3e-14 52.1 0.1 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAP85760.1 - 1e-12 47.3 0.0 2.4e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 GAP85760.1 - 0.00023 20.8 0.3 0.00099 18.7 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CcmH PF03918.9 GAP85760.1 - 0.032 13.2 0.4 0.43 9.5 0.2 2.5 2 0 0 2 2 2 0 Cytochrome C biogenesis protein DUF2231 PF09990.4 GAP85760.1 - 0.033 14.5 0.5 0.033 14.5 0.3 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) DUF2207 PF09972.4 GAP85760.1 - 9.7 4.6 6.6 1.2 7.6 0.0 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Abhydrolase_6 PF12697.2 GAP85761.1 - 2.9e-33 115.6 3.2 3.6e-33 115.3 2.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP85761.1 - 5.5e-12 45.6 0.1 1.6e-11 44.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP85761.1 - 4.6e-10 39.4 0.0 9.1e-10 38.4 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 GAP85761.1 - 5.3e-07 29.3 0.0 9.5e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 GAP85761.1 - 0.00073 18.0 0.0 0.0011 17.5 0.0 1.2 1 0 0 1 1 1 1 Ndr family Chlorophyllase2 PF12740.2 GAP85761.1 - 0.03 13.2 0.0 0.21 10.4 0.0 2.3 3 0 0 3 3 3 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 GAP85761.1 - 0.06 12.1 0.0 0.24 10.1 0.0 2.0 2 0 0 2 2 2 0 Chlorophyllase DUF2457 PF10446.4 GAP85762.1 - 3.8e-05 22.6 10.0 4.6e-05 22.3 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) TRAP_alpha PF03896.11 GAP85762.1 - 0.0016 17.4 0.9 0.002 17.1 0.6 1.0 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DARPP-32 PF05395.7 GAP85762.1 - 0.0092 16.1 0.1 0.011 15.8 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase inhibitor 1/DARPP-32 LRR19-TM PF15176.1 GAP85762.1 - 0.013 15.2 0.2 0.022 14.4 0.1 1.4 1 1 1 2 2 2 0 Leucine-rich repeat family 19 TM domain CobT PF06213.7 GAP85762.1 - 0.017 14.3 8.5 0.019 14.0 5.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1510 PF07423.6 GAP85762.1 - 0.025 13.9 0.0 0.033 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Sporozoite_P67 PF05642.6 GAP85762.1 - 0.042 11.7 2.5 0.05 11.4 1.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CENP-T PF15511.1 GAP85762.1 - 0.047 12.9 5.5 0.054 12.7 3.8 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T FAM176 PF14851.1 GAP85762.1 - 0.052 13.2 0.2 0.076 12.6 0.1 1.2 1 0 0 1 1 1 0 FAM176 family Polyoma_lg_T_C PF06431.6 GAP85762.1 - 0.11 11.1 1.6 0.15 10.7 1.1 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus Ctr PF04145.10 GAP85762.1 - 0.14 12.2 0.0 0.17 11.9 0.0 1.1 1 0 0 1 1 1 0 Ctr copper transporter family DUF2201_N PF13203.1 GAP85762.1 - 0.55 9.3 2.9 0.69 9.0 2.0 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain Paf1 PF03985.8 GAP85762.1 - 0.89 8.2 6.2 1.1 7.9 4.3 1.0 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.7 GAP85762.1 - 0.94 7.3 10.8 1.1 7.1 7.5 1.0 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.7 GAP85762.1 - 1.5 7.1 7.5 1.8 6.8 5.2 1.0 1 0 0 1 1 1 0 Mpp10 protein SMN PF06003.7 GAP85762.1 - 1.5 7.8 10.7 3 6.8 7.4 1.5 1 1 0 1 1 1 0 Survival motor neuron protein (SMN) Herpes_LMP1 PF05297.6 GAP85762.1 - 1.7 7.4 6.3 2 7.2 4.4 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) BUD22 PF09073.5 GAP85762.1 - 3 6.7 9.6 3.5 6.6 6.7 1.0 1 0 0 1 1 1 0 BUD22 Osteopontin PF00865.13 GAP85762.1 - 4.6 6.3 16.1 5.4 6.1 11.2 1.0 1 0 0 1 1 1 0 Osteopontin CDC45 PF02724.9 GAP85762.1 - 8.1 4.3 10.8 10 4.0 7.5 1.0 1 0 0 1 1 1 0 CDC45-like protein IDO PF01231.13 GAP85763.1 - 4.6e-162 539.2 0.0 5.3e-162 539.0 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase UEV PF05743.8 GAP85764.1 - 2.5e-36 124.0 0.0 4.3e-36 123.2 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 GAP85764.1 - 2.5e-20 71.8 0.0 4.4e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.21 GAP85764.1 - 0.015 14.7 0.1 0.029 13.8 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme DUF1764 PF08576.5 GAP85765.1 - 0.63 10.8 9.2 2.7 8.8 6.4 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Abhydrolase_3 PF07859.8 GAP85766.1 - 7.8e-29 100.7 0.1 9.8e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 GAP85766.1 - 1e-13 50.7 0.0 1.4e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 GAP85766.1 - 0.0034 17.1 0.0 0.0048 16.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAP85766.1 - 0.017 14.3 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF3089 PF11288.3 GAP85766.1 - 0.067 12.3 0.1 0.28 10.3 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3089) CFEM PF05730.6 GAP85767.1 - 1.1e-13 50.7 12.5 1.7e-13 50.1 8.6 1.3 1 0 0 1 1 1 1 CFEM domain DUF829 PF05705.9 GAP85768.1 - 3.5e-37 128.4 0.0 4.5e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 GAP85768.1 - 0.0049 16.7 2.5 0.027 14.3 1.8 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.11 GAP85769.1 - 5e-31 107.6 46.5 2.2e-26 92.4 16.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAP85769.1 - 4.5e-13 48.2 11.1 5.5e-13 47.9 7.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ketoacyl-synt PF00109.21 GAP85770.1 - 1.2e-70 237.8 1.2 3.4e-70 236.4 0.8 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAP85770.1 - 8.4e-59 199.4 0.0 1.2e-58 198.9 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 GAP85770.1 - 3.5e-44 151.1 0.3 6.3e-44 150.3 0.2 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 GAP85770.1 - 4.4e-35 120.1 0.1 1.4e-34 118.4 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 GAP85770.1 - 5.5e-15 55.6 0.0 1.4e-14 54.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP85770.1 - 1.5e-11 44.2 0.0 3.2e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP85770.1 - 2.1e-10 41.1 0.0 6.7e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP85770.1 - 5.3e-09 36.4 0.0 1.8e-08 34.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP85770.1 - 2.4e-08 33.7 0.0 8.7e-08 31.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP85770.1 - 3.8e-05 23.6 0.0 0.0001 22.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP85770.1 - 0.00016 21.9 0.0 0.0005 20.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP85770.1 - 0.00027 20.1 0.0 0.0005 19.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.1 GAP85770.1 - 0.00043 21.0 0.0 0.0026 18.5 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 GAP85770.1 - 0.0013 18.0 0.0 0.0026 17.0 0.0 1.4 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Thiolase_N PF00108.18 GAP85770.1 - 0.0059 15.6 0.4 0.012 14.6 0.3 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 GAP85770.1 - 0.0065 15.9 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase RrnaAD PF00398.15 GAP85770.1 - 0.026 13.5 0.0 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase KR PF08659.5 GAP85771.1 - 5.3e-63 211.9 2.6 5.4e-63 211.9 0.0 2.3 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 GAP85771.1 - 1.2e-47 161.9 1.4 1.1e-46 158.8 0.0 2.7 3 0 0 3 3 3 1 short chain dehydrogenase ADH_zinc_N PF00107.21 GAP85771.1 - 1.4e-18 66.7 0.0 7.1e-18 64.4 0.0 2.2 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAP85771.1 - 1.4e-13 51.8 0.1 1.2e-12 48.7 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.20 GAP85771.1 - 1.9e-09 37.6 0.0 5.5e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site PALP PF00291.20 GAP85771.1 - 0.0097 15.1 0.1 0.045 12.9 0.0 2.0 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme WD40 PF00400.27 GAP85772.1 - 1e-40 136.1 21.2 6.3e-13 48.0 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat NACHT PF05729.7 GAP85772.1 - 6e-07 29.2 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 GAP85772.1 - 0.032 13.9 0.0 0.13 12.0 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain FTA4 PF13093.1 GAP85773.1 - 1.7e-09 37.4 0.2 2.1e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Peptidase_C2 PF00648.16 GAP85774.1 - 1.5e-58 198.2 1.6 5.4e-39 133.9 0.6 2.4 2 0 0 2 2 2 2 Calpain family cysteine protease OAD_gamma PF04277.8 GAP85774.1 - 0.02 15.2 0.1 0.02 15.2 0.0 5.2 3 2 1 4 4 4 0 Oxaloacetate decarboxylase, gamma chain Glyco_hydro_16 PF00722.16 GAP85775.1 - 8.5e-19 67.5 0.0 1.4e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 GAP85775.1 - 0.00069 17.8 1.8 0.18 9.9 0.5 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) F-box PF00646.28 GAP85776.1 - 1.1e-08 34.5 1.7 2.7e-08 33.2 1.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAP85776.1 - 2.3e-07 30.4 1.9 8.9e-07 28.5 1.3 2.1 1 0 0 1 1 1 1 F-box-like Apc3 PF12895.2 GAP85776.1 - 0.00019 21.4 0.1 0.017 15.2 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 GAP85776.1 - 0.0045 17.6 4.7 0.37 11.5 0.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAP85776.1 - 0.018 14.7 1.6 0.56 9.8 0.0 2.9 2 1 0 3 3 3 0 TPR repeat TPR_6 PF13174.1 GAP85776.1 - 0.038 14.4 5.2 18 6.0 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAP85776.1 - 0.075 13.3 2.1 0.97 9.8 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAP85776.1 - 0.1 12.2 0.1 3 7.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAP85776.1 - 0.38 11.5 6.6 3.1 8.6 0.4 3.6 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAP85776.1 - 0.45 10.4 4.5 3.1 7.8 0.9 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAP85776.1 - 1.5 8.9 7.6 14 5.9 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat ADIP PF11559.3 GAP85777.1 - 9e-41 139.2 6.6 2.8e-40 137.6 4.6 1.9 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding PS_Dcarbxylase PF02666.10 GAP85778.1 - 1.7e-53 180.9 0.0 3.4e-53 179.9 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 GAP85778.1 - 4e-33 113.1 0.0 1.3e-15 56.9 0.0 2.6 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.1 GAP85778.1 - 0.0009 19.3 0.0 0.0043 17.1 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 GAP85778.1 - 0.0029 16.7 0.6 0.0075 15.5 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 GAP85778.1 - 0.0033 17.1 0.3 0.027 14.3 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain PBP1_TM PF14812.1 GAP85778.1 - 0.022 15.0 4.8 0.067 13.5 3.3 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CEP76-C2 PF15627.1 GAP85778.1 - 0.094 12.2 0.1 0.36 10.3 0.0 1.9 2 0 0 2 2 2 0 CEP76 C2 domain DUF2413 PF10310.4 GAP85778.1 - 5.5 5.6 7.6 11 4.6 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) HAD PF12710.2 GAP85779.1 - 7.1e-10 39.3 0.0 1.2e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 GAP85779.1 - 0.0024 17.0 0.0 1.5 7.8 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase Hydrolase PF00702.21 GAP85779.1 - 0.004 17.6 0.0 0.59 10.5 0.1 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 GAP85779.1 - 0.17 11.2 0.0 0.35 10.1 0.0 1.5 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) dCMP_cyt_deam_1 PF00383.17 GAP85780.1 - 8.6e-13 47.8 0.0 1.3e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF3391 PF11871.3 GAP85780.1 - 0.027 14.6 0.2 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) NACHT PF05729.7 GAP85781.1 - 1.3e-07 31.4 0.0 3.7e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Abhydrolase_6 PF12697.2 GAP85781.1 - 6.9e-06 26.0 0.2 2.9e-05 24.0 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family AAA_16 PF13191.1 GAP85781.1 - 0.00015 21.8 0.1 0.00063 19.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain PGAP1 PF07819.8 GAP85781.1 - 0.00015 21.4 0.1 0.0004 20.0 0.1 1.6 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 GAP85781.1 - 0.00099 18.8 0.0 0.0034 17.1 0.0 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 GAP85781.1 - 0.001 18.4 0.0 0.0025 17.1 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_19 PF13245.1 GAP85781.1 - 0.0044 16.7 0.1 0.052 13.2 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 GAP85781.1 - 0.0047 17.7 0.0 0.019 15.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAP85781.1 - 0.0064 16.6 0.2 0.085 12.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 GAP85781.1 - 0.02 14.7 0.0 0.09 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 GAP85781.1 - 0.043 13.9 0.0 0.098 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 GAP85781.1 - 0.043 14.1 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 GAP85781.1 - 0.049 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_10 PF12846.2 GAP85781.1 - 0.07 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain Flu_C_NS1 PF03506.8 GAP85781.1 - 0.09 12.5 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) NTPase_1 PF03266.10 GAP85781.1 - 0.11 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_29 PF13555.1 GAP85781.1 - 0.12 11.8 1.0 0.26 10.8 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA PF00004.24 GAP85781.1 - 0.12 12.5 0.0 0.41 10.8 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MARVEL PF01284.18 GAP85784.1 - 2.7e-07 30.4 9.6 2.7e-07 30.4 6.6 1.8 1 1 0 2 2 2 1 Membrane-associating domain DUF1774 PF08611.5 GAP85784.1 - 0.046 13.8 3.2 0.046 13.8 2.2 3.1 2 1 1 3 3 3 0 Fungal protein of unknown function (DUF1774) Wzy_C PF04932.10 GAP85784.1 - 0.14 11.8 3.1 0.27 11.0 2.2 1.5 1 1 0 1 1 1 0 O-Antigen ligase DUF4131 PF13567.1 GAP85784.1 - 0.37 10.1 5.3 1.2 8.5 0.1 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) FA_desaturase PF00487.19 GAP85784.1 - 0.57 9.5 9.6 0.77 9.1 6.6 1.2 1 0 0 1 1 1 0 Fatty acid desaturase SIS PF01380.17 GAP85785.1 - 2.3e-11 43.3 0.0 5.1e-11 42.2 0.0 1.6 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.1 GAP85785.1 - 0.0036 17.0 0.0 0.01 15.5 0.0 1.7 1 1 0 1 1 1 1 SIS domain DAO PF01266.19 GAP85786.1 - 1.6e-24 86.5 1.3 6.3e-24 84.5 0.9 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAP85786.1 - 0.00014 21.7 0.0 0.00052 19.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 GAP85786.1 - 0.00037 20.3 0.2 0.0007 19.4 0.1 1.4 1 0 0 1 1 1 1 ThiF family Pyr_redox PF00070.22 GAP85786.1 - 0.0039 17.5 0.1 0.007 16.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAP85786.1 - 0.0043 16.9 0.1 0.038 13.8 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 GAP85786.1 - 0.0074 16.0 0.1 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 GAP85786.1 - 0.024 14.2 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 GAP85786.1 - 0.045 12.6 0.1 0.57 8.9 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.1 GAP85786.1 - 0.13 12.5 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 GAP85786.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase p450 PF00067.17 GAP85787.1 - 2.2e-70 237.5 0.0 2.8e-70 237.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RRM_1 PF00076.17 GAP85789.1 - 3.1e-17 61.9 0.2 1e-16 60.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP85789.1 - 7.1e-16 57.9 0.0 1.2e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP85789.1 - 0.00015 21.5 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GAS PF13851.1 GAP85789.1 - 0.0046 16.1 1.0 0.0064 15.7 0.7 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF904 PF06005.7 GAP85789.1 - 0.0047 17.2 2.7 0.0077 16.4 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF904) APG6 PF04111.7 GAP85789.1 - 0.027 13.5 0.3 0.032 13.2 0.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 NPBW PF15180.1 GAP85789.1 - 0.12 11.9 0.1 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Neuropeptides B and W IncA PF04156.9 GAP85789.1 - 0.16 11.5 0.5 0.21 11.1 0.4 1.1 1 0 0 1 1 1 0 IncA protein GRP PF07172.6 GAP85789.1 - 1.8 9.1 19.4 1 9.8 10.8 2.1 2 0 0 2 2 2 0 Glycine rich protein family WD40 PF00400.27 GAP85790.1 - 1.4e-31 107.2 12.8 2e-10 40.1 0.1 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 GAP85790.1 - 0.02 13.0 0.1 3.8 5.5 0.0 3.4 2 1 0 3 3 3 0 Nucleoporin Nup120/160 Zn_clus PF00172.13 GAP85793.1 - 2.7e-09 36.7 15.6 4.4e-09 36.1 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Snapin_Pallidin PF14712.1 GAP85793.1 - 0.065 13.5 0.3 0.15 12.3 0.2 1.6 1 0 0 1 1 1 0 Snapin/Pallidin APG5 PF04106.7 GAP85794.1 - 7e-44 149.6 0.0 1.3e-43 148.7 0.0 1.5 1 1 0 1 1 1 1 Autophagy protein Apg5 Ten1 PF12658.2 GAP85797.1 - 8.4e-27 93.3 0.0 1.1e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.1 GAP85797.1 - 0.00015 21.3 0.0 0.00031 20.2 0.0 1.6 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit Rep_fac-A_3 PF08661.6 GAP85797.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Replication factor A protein 3 Snf7 PF03357.16 GAP85798.1 - 8.5e-33 113.1 21.9 8.5e-33 113.1 15.1 2.0 1 1 1 2 2 2 1 Snf7 PAS_10 PF13596.1 GAP85798.1 - 0.075 13.3 0.5 0.21 11.8 0.1 1.9 1 1 1 2 2 2 0 PAS domain MutS_III PF05192.13 GAP85798.1 - 0.99 9.1 6.2 1.4 8.7 4.3 1.3 1 0 0 1 1 1 0 MutS domain III Allexi_40kDa PF05549.6 GAP85798.1 - 3.1 6.9 10.8 1 8.6 4.3 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF2120 PF09893.4 GAP85798.1 - 3.7 7.5 6.4 3.8 7.4 0.2 2.5 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DUF3138 PF11336.3 GAP85798.1 - 4.5 5.3 11.6 4.7 5.2 4.4 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3138) BLOC1_2 PF10046.4 GAP85798.1 - 8.3 6.6 13.1 1 9.5 3.8 2.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1216 PF06746.6 GAP85798.1 - 8.5 6.1 9.5 1.1 9.0 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1216) Gly-zipper_Omp PF13488.1 GAP85801.1 - 0.0011 18.5 22.2 0.014 15.0 3.9 4.3 4 1 0 4 4 4 3 Glycine zipper Gly-zipper_OmpA PF13436.1 GAP85801.1 - 0.015 14.9 2.0 0.015 14.9 1.4 4.5 3 2 2 5 5 5 0 Glycine-zipper containing OmpA-like membrane domain DUF2910 PF11139.3 GAP85801.1 - 0.074 12.1 0.2 12 4.9 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2910) DUF533 PF04391.7 GAP85801.1 - 1 8.7 22.3 1.7 7.9 0.1 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF533) Spermine_synth PF01564.12 GAP85802.1 - 9.2e-97 322.7 0.0 1.5e-96 322.1 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 GAP85802.1 - 4.7e-06 27.1 0.0 8.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP85802.1 - 1.7e-05 24.4 0.0 2.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP85802.1 - 0.0036 17.0 0.0 0.013 15.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 GAP85802.1 - 0.0042 16.1 0.0 0.0066 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_2 PF00891.13 GAP85802.1 - 0.0086 15.2 0.2 0.12 11.6 0.0 2.4 1 1 1 2 2 2 1 O-methyltransferase Methyltransf_12 PF08242.7 GAP85802.1 - 0.012 16.0 0.1 0.071 13.5 0.0 2.2 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_30 PF05430.6 GAP85802.1 - 0.035 13.7 0.0 0.077 12.6 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_24 PF13578.1 GAP85802.1 - 0.049 14.4 0.1 0.18 12.6 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain DUF3597 PF12200.3 GAP85802.1 - 0.16 12.3 1.1 19 5.6 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Ran_BP1 PF00638.13 GAP85803.1 - 2e-12 47.2 0.0 3.8e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain SCP2 PF02036.12 GAP85804.1 - 4.7e-24 84.6 0.2 5.9e-24 84.3 0.1 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 GAP85804.1 - 4.3e-06 26.7 0.2 1e-05 25.4 0.1 1.6 1 1 1 2 2 2 1 Alkyl sulfatase C-terminal Fungal_trans_2 PF11951.3 GAP85805.1 - 1.2e-54 185.3 6.6 1.6e-54 185.0 4.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP85805.1 - 1.9e-08 34.1 5.0 3.2e-08 33.3 3.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CN_hydrolase PF00795.17 GAP85806.1 - 1.8e-31 108.9 0.0 2.3e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase AA_permease_2 PF13520.1 GAP85807.1 - 2.9e-49 167.7 48.9 3.6e-49 167.4 33.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAP85807.1 - 9e-27 93.5 41.9 1.1e-26 93.2 29.0 1.0 1 0 0 1 1 1 1 Amino acid permease GCS PF03074.11 GAP85808.1 - 1.8e-153 510.9 0.0 2.3e-153 510.6 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GATA PF00320.22 GAP85809.1 - 9.9e-16 56.8 3.4 1.6e-15 56.1 2.3 1.4 1 0 0 1 1 1 1 GATA zinc finger Periviscerokin PF08259.6 GAP85810.1 - 0.092 12.8 3.8 0.25 11.5 2.7 1.8 1 0 0 1 1 1 0 Periviscerokinin family MFS_1 PF07690.11 GAP85811.1 - 5.5e-06 25.3 40.6 4e-05 22.5 22.3 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily MARVEL PF01284.18 GAP85812.1 - 4.1e-19 68.8 14.5 5.2e-19 68.4 10.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain HemY_N PF07219.8 GAP85812.1 - 0.066 12.7 0.2 0.066 12.7 0.2 2.3 2 0 0 2 2 2 0 HemY protein N-terminus Polysacc_synt_C PF14667.1 GAP85812.1 - 2.5 7.8 9.3 2 8.1 2.1 2.3 1 1 1 2 2 2 0 Polysaccharide biosynthesis C-terminal domain DUF485 PF04341.7 GAP85812.1 - 8.3 6.1 8.2 0.97 9.1 2.5 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Collagen PF01391.13 GAP85813.1 - 1.3e-07 31.0 39.0 3.7e-06 26.3 10.6 5.1 4 1 1 5 5 5 2 Collagen triple helix repeat (20 copies) Methyltransf_23 PF13489.1 GAP85814.1 - 1.9e-09 37.4 0.0 3.8e-09 36.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP85814.1 - 5.2e-06 26.8 0.0 0.00014 22.2 0.0 2.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP85814.1 - 0.00049 20.5 0.0 0.00087 19.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP85814.1 - 0.00053 19.1 0.0 0.00087 18.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 GAP85814.1 - 0.0037 17.8 0.0 0.0056 17.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP85814.1 - 0.021 14.8 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 GAP85814.1 - 0.084 11.8 0.0 0.2 10.5 0.0 1.6 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family DnaJ PF00226.26 GAP85815.1 - 9.7e-26 89.2 0.8 1.6e-25 88.6 0.6 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 GAP85815.1 - 5.6e-15 55.1 15.3 1.1e-14 54.2 10.6 1.5 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 GAP85815.1 - 9.2e-13 47.9 0.0 6.7e-12 45.1 0.0 2.2 2 0 0 2 2 2 1 DnaJ C terminal domain HypA PF01155.14 GAP85815.1 - 0.082 12.5 7.8 0.81 9.3 0.6 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family OB_NTP_bind PF07717.11 GAP85816.1 - 1.7e-27 95.5 0.0 4.1e-27 94.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 GAP85816.1 - 3.7e-24 84.6 0.1 3.7e-24 84.6 0.1 3.1 5 0 0 5 5 5 1 Helicase associated domain (HA2) Helicase_C PF00271.26 GAP85816.1 - 4.6e-13 48.8 0.0 1.1e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 GAP85816.1 - 1.3e-05 25.3 0.0 4.4e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 GAP85816.1 - 8.2e-05 22.1 0.0 0.00019 20.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 GAP85816.1 - 0.0015 17.5 0.0 0.0037 16.1 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 GAP85816.1 - 0.029 13.7 0.0 0.064 12.6 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.22 GAP85816.1 - 0.03 14.6 0.0 0.13 12.5 0.0 2.1 1 0 0 1 1 1 0 ABC transporter G-alpha PF00503.15 GAP85817.1 - 7.7e-115 383.6 1.0 9.1e-115 383.4 0.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAP85817.1 - 5.1e-13 48.6 1.3 3.8e-08 32.7 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAP85817.1 - 0.00029 20.0 0.5 0.061 12.4 0.0 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_25 PF13481.1 GAP85817.1 - 0.01 15.2 0.0 0.025 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 GAP85817.1 - 0.077 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Malic_M PF03949.10 GAP85817.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Glyco_hydro_3 PF00933.16 GAP85818.1 - 2.9e-87 292.4 0.0 4.6e-87 291.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAP85818.1 - 3.6e-39 134.6 0.0 6.4e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAP85818.1 - 1e-21 76.6 0.0 1.8e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Fungal_trans PF04082.13 GAP85819.1 - 2.7e-10 39.5 0.1 5.2e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP85819.1 - 4.2e-08 32.9 15.0 9.8e-08 31.7 10.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPX PF03105.14 GAP85820.1 - 5e-19 69.1 1.7 7.4e-10 39.0 0.0 3.4 2 1 1 3 3 3 2 SPX domain DUF4203 PF13886.1 GAP85820.1 - 0.086 12.2 8.6 0.12 11.8 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) GAF_2 PF13185.1 GAP85821.1 - 5.8e-06 26.8 0.0 1.2e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 GAP85821.1 - 0.018 15.2 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 GAF domain CN_hydrolase PF00795.17 GAP85822.1 - 5.8e-32 110.5 0.0 7.9e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase BiPBP_C PF06832.7 GAP85822.1 - 0.014 15.2 0.0 0.042 13.7 0.0 1.8 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family HET PF06985.6 GAP85823.1 - 5.3e-33 114.1 1.3 1.1e-32 113.1 0.9 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Kelch_6 PF13964.1 GAP85824.1 - 9.8e-06 25.5 2.8 0.17 12.1 0.1 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 GAP85824.1 - 5.3e-05 22.8 0.3 0.0016 18.1 0.0 2.8 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.20 GAP85824.1 - 0.00011 21.6 0.0 0.0041 16.6 0.0 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 GAP85824.1 - 0.00021 21.3 3.9 0.022 14.9 0.0 3.4 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 GAP85824.1 - 0.0047 16.8 1.7 16 5.5 0.0 3.9 3 1 0 3 3 3 1 Kelch motif EphA2_TM PF14575.1 GAP85824.1 - 0.006 16.9 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 GAP85824.1 - 0.08 11.1 0.0 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E VSP PF03302.8 GAP85824.1 - 0.2 10.2 1.3 0.29 9.7 0.9 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein DAP10 PF07213.6 GAP85824.1 - 0.23 11.2 1.4 0.29 10.9 0.1 1.8 2 0 0 2 2 2 0 DAP10 membrane protein zf-C2H2_6 PF13912.1 GAP85825.1 - 0.13 12.2 2.2 0.3 11.0 1.5 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 GAP85825.1 - 3.9 8.0 7.1 0.27 11.6 0.9 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type ArfGap PF01412.13 GAP85826.1 - 6e-40 135.6 0.2 1.2e-39 134.6 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.26 GAP85826.1 - 0.13 12.0 0.1 0.31 10.9 0.1 1.7 1 0 0 1 1 1 0 UBA/TS-N domain Pyridoxal_deC PF00282.14 GAP85829.1 - 3.8e-26 91.4 0.0 5.9e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 GAP85829.1 - 1.2e-06 27.9 0.0 1.6e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 GAP85829.1 - 0.0014 17.6 0.0 0.002 17.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Pkinase PF00069.20 GAP85830.1 - 5.9e-36 123.9 0.0 7.7e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP85830.1 - 2.8e-14 52.7 0.0 3.6e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAP85830.1 - 0.016 14.9 0.0 0.56 9.9 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family EMP24_GP25L PF01105.19 GAP85831.1 - 2e-53 180.8 0.1 2.3e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF1319 PF07028.6 GAP85831.1 - 0.077 13.1 0.5 0.12 12.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) Shugoshin_N PF07558.6 GAP85831.1 - 0.088 12.5 0.3 0.16 11.6 0.2 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region PspB PF06667.7 GAP85831.1 - 0.24 11.3 1.2 0.43 10.5 0.8 1.4 1 0 0 1 1 1 0 Phage shock protein B Imm44 PF15584.1 GAP85833.1 - 0.046 13.5 0.0 0.062 13.1 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 44 Kinesin PF00225.18 GAP85834.1 - 7.3e-107 356.9 0.0 2.3e-106 355.3 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.3 GAP85834.1 - 5.8e-42 142.6 0.0 2.4e-41 140.7 0.0 2.1 2 0 0 2 2 2 1 Kinesin protein KIF1B PF12423.3 GAP85834.1 - 1.1e-06 28.5 1.0 2.8e-06 27.2 0.7 1.8 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 GAP85834.1 - 0.00017 21.6 0.3 0.0011 19.0 0.2 2.4 2 0 0 2 2 2 1 FHA domain PH PF00169.24 GAP85834.1 - 0.00068 19.8 0.0 0.0026 17.9 0.0 2.1 1 0 0 1 1 1 1 PH domain V_ATPase_I PF01496.14 GAP85834.1 - 0.32 8.8 6.6 0.05 11.4 1.3 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Peptidase_M1 PF01433.15 GAP85835.1 - 1.6e-63 215.1 0.0 5.8e-63 213.3 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 GAP85835.1 - 1.9e-33 115.0 0.0 3.8e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 GAP85835.1 - 6.3e-18 65.0 0.1 1.2e-17 64.1 0.1 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2697 PF10906.3 GAP85835.1 - 0.088 12.8 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2697) Peptidase_M61 PF05299.7 GAP85835.1 - 0.24 11.4 2.2 1.7 8.6 1.5 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Uds1 PF15456.1 GAP85836.1 - 6.9e-33 113.2 9.6 1.5e-32 112.2 6.6 1.6 1 0 0 1 1 1 1 Up-regulated During Septation TBPIP PF07106.8 GAP85836.1 - 0.21 11.1 0.7 1.3 8.5 0.5 2.0 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Wbp11 PF09429.5 GAP85836.1 - 0.33 10.9 5.0 0.046 13.6 0.6 1.8 2 0 0 2 2 2 0 WW domain binding protein 11 IncA PF04156.9 GAP85836.1 - 7.5 6.1 5.8 14 5.1 4.0 1.4 1 0 0 1 1 1 0 IncA protein Ank_2 PF12796.2 GAP85837.1 - 0.036 14.4 0.0 0.12 12.7 0.0 2.0 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Trm112p PF03966.11 GAP85837.1 - 0.045 14.1 0.2 0.1 12.9 0.1 1.8 1 0 0 1 1 1 0 Trm112p-like protein zf-RING_2 PF13639.1 GAP85837.1 - 0.1 12.4 8.5 0.31 10.9 5.9 1.9 1 1 0 1 1 1 0 Ring finger domain Ank PF00023.25 GAP85837.1 - 0.11 12.3 0.0 12 5.9 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeat DUF2011 PF09428.5 GAP85838.1 - 0.0041 16.9 0.0 0.0085 15.9 0.0 1.6 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF2011) ORC5_C PF14630.1 GAP85838.1 - 0.017 14.5 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus Proteasome PF00227.21 GAP85839.1 - 1.9e-48 164.3 0.0 2.5e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 GAP85839.1 - 2.8e-12 45.7 0.1 2.8e-12 45.7 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature SCP2 PF02036.12 GAP85839.1 - 0.037 14.3 0.0 0.088 13.1 0.0 1.6 2 0 0 2 2 2 0 SCP-2 sterol transfer family DUF2373 PF10180.4 GAP85840.1 - 4.3e-17 61.4 0.0 8e-17 60.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) DFF40 PF09230.5 GAP85840.1 - 0.42 9.9 2.6 0.68 9.2 1.8 1.2 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa FancD2 PF14631.1 GAP85840.1 - 1.3 6.0 4.3 1.8 5.5 3.0 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Claudin_2 PF13903.1 GAP85841.1 - 1.4e-05 24.8 2.0 2.3e-05 24.1 1.4 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HGMIC_fpl PF10242.4 GAP85841.1 - 0.00032 20.7 1.1 0.00081 19.4 0.8 1.8 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein DHquinase_I PF01487.10 GAP85842.1 - 1.4e-55 188.3 0.0 2e-55 187.9 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase Fungal_trans PF04082.13 GAP85843.1 - 2.4e-26 92.1 0.0 3.5e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP85843.1 - 1.3e-05 24.9 15.8 2.7e-05 23.9 11.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2360 PF10152.4 GAP85843.1 - 0.044 14.0 1.2 0.12 12.6 0.8 1.7 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) HET PF06985.6 GAP85844.1 - 1.3e-28 99.8 3.4 2.4e-28 99.0 2.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ketoacyl-synt PF00109.21 GAP85848.1 - 5.3e-72 242.3 0.3 2e-71 240.4 0.4 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 GAP85848.1 - 7.2e-32 109.7 0.0 1.3e-31 108.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 GAP85848.1 - 5.9e-19 68.5 0.0 1e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PP-binding PF00550.20 GAP85848.1 - 1.6e-18 66.6 0.8 1.7e-08 34.5 0.1 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 GAP85848.1 - 4.9e-18 65.4 0.0 2.3e-17 63.2 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain PS-DH PF14765.1 GAP85848.1 - 6.3e-16 58.3 0.0 9.9e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_23 PF13489.1 GAP85848.1 - 1e-12 48.0 0.0 5.2e-12 45.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP85848.1 - 9.3e-08 32.4 0.0 5.7e-07 29.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP85848.1 - 2e-06 27.4 0.0 4.8e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP85848.1 - 0.00022 21.7 0.0 0.0011 19.5 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 GAP85848.1 - 0.00065 18.7 0.1 0.0015 17.5 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 GAP85848.1 - 0.0016 17.6 0.0 0.0033 16.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF367 PF04034.8 GAP85848.1 - 0.13 11.8 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF367) FAD_binding_4 PF01565.18 GAP85849.1 - 1.5e-19 69.8 1.8 1.5e-19 69.8 1.3 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 GAP85849.1 - 0.001 18.8 0.7 0.0022 17.8 0.5 1.6 1 0 0 1 1 1 1 Berberine and berberine like Guanylin PF02058.10 GAP85849.1 - 0.0013 18.7 0.0 0.0033 17.4 0.0 1.6 1 0 0 1 1 1 1 Guanylin precursor Methyltransf_2 PF00891.13 GAP85851.1 - 4e-33 114.6 0.0 1.1e-32 113.1 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_18 PF12847.2 GAP85851.1 - 3.8e-06 27.4 0.0 7.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP85851.1 - 0.0011 19.4 0.0 0.0021 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP85851.1 - 0.0023 18.2 0.0 0.0064 16.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAP85851.1 - 0.0047 15.9 0.0 0.0083 15.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 GAP85851.1 - 0.057 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 GAP85851.1 - 0.071 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain CheR PF01739.13 GAP85851.1 - 0.12 11.6 0.1 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_26 PF13659.1 GAP85851.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox_3 PF13738.1 GAP85852.1 - 3.4e-23 82.7 0.0 7.8e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP85852.1 - 3.3e-12 46.2 0.0 7.1e-11 41.9 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 GAP85852.1 - 4e-12 45.1 0.0 1.6e-11 43.1 0.0 1.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 GAP85852.1 - 2.4e-06 27.5 0.0 7.2e-06 26.0 0.0 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAP85852.1 - 2.4e-06 26.6 1.5 0.0066 15.3 0.1 3.0 2 2 2 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 GAP85852.1 - 7e-06 25.1 0.2 0.0001 21.3 0.0 2.6 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 GAP85852.1 - 4.2e-05 23.3 0.1 0.065 13.0 0.0 3.4 3 1 1 4 4 4 1 FAD-NAD(P)-binding Mqo PF06039.10 GAP85852.1 - 0.00086 17.6 0.1 0.36 8.9 0.0 2.1 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.12 GAP85852.1 - 0.0024 17.0 0.2 0.0061 15.6 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 GAP85852.1 - 0.019 15.3 0.6 7.3 7.0 0.2 2.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Semialdhyde_dh PF01118.19 GAP85852.1 - 0.062 13.6 0.1 22 5.3 0.0 3.6 4 0 0 4 4 3 0 Semialdehyde dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 GAP85852.1 - 0.09 11.8 0.3 0.16 11.0 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Bac_luciferase PF00296.15 GAP85853.1 - 1.9e-63 214.4 0.0 2.8e-63 213.8 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.11 GAP85853.1 - 3.2e-27 95.1 33.3 4.5e-27 94.7 23.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TPR_10 PF13374.1 GAP85853.1 - 0.075 12.9 0.3 0.19 11.7 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Bac_luciferase PF00296.15 GAP85854.1 - 1.2e-62 211.8 1.1 1.5e-62 211.4 0.8 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.11 GAP85855.1 - 6.5e-07 28.3 32.7 1.4e-06 27.2 22.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 GAP85855.1 - 1.8e-06 27.5 4.6 1.8e-06 27.5 3.2 2.4 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 DUF3433 PF11915.3 GAP85857.1 - 2.1e-27 95.0 9.6 4.5e-17 61.9 0.5 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) SDF PF00375.13 GAP85858.1 - 0.074 11.7 0.0 0.088 11.5 0.0 1.0 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family GDPD PF03009.12 GAP85859.1 - 4.7e-33 114.7 0.0 6.6e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 GAP85859.1 - 0.034 14.3 0.3 0.31 11.2 0.1 2.5 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family Fungal_trans PF04082.13 GAP85860.1 - 3.6e-33 114.5 0.3 7e-33 113.5 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP85860.1 - 1.2e-09 37.9 11.7 2.2e-09 37.0 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC144C PF14915.1 GAP85860.1 - 0.037 12.9 0.8 0.053 12.4 0.0 1.6 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region DUF4635 PF15466.1 GAP85860.1 - 0.14 11.4 0.4 0.44 9.8 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) DUF1440 PF07274.7 GAP85860.1 - 0.25 11.3 1.2 1.6 8.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1440) Macoilin PF09726.4 GAP85860.1 - 4.5 5.4 6.4 1.3 7.2 0.0 2.0 2 0 0 2 2 2 0 Transmembrane protein bZIP_1 PF00170.16 GAP85860.1 - 7.9 6.5 5.8 0.5 10.3 0.1 1.9 2 0 0 2 2 2 0 bZIP transcription factor SET PF00856.23 GAP85861.1 - 0.11 12.7 0.0 0.33 11.2 0.0 1.8 2 0 0 2 2 2 0 SET domain MMR_HSR1_C PF08438.5 GAP85862.1 - 4.6e-31 107.2 0.0 8.4e-31 106.4 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 GAP85862.1 - 4e-19 68.6 0.0 8.2e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAP85862.1 - 3.2e-10 39.4 0.2 1.7e-07 30.6 0.0 2.7 3 0 0 3 3 3 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 GAP85862.1 - 0.00013 21.4 0.0 0.12 11.8 0.0 2.6 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 GAP85862.1 - 0.0095 15.7 0.1 0.14 11.9 0.1 2.2 2 0 0 2 2 2 1 Dynamin family ABC_tran PF00005.22 GAP85862.1 - 0.016 15.4 0.0 0.38 11.0 0.0 2.5 3 0 0 3 3 3 0 ABC transporter ArgK PF03308.11 GAP85862.1 - 0.03 13.0 0.3 0.11 11.2 0.0 2.0 2 0 0 2 2 2 0 ArgK protein AAA_30 PF13604.1 GAP85862.1 - 0.11 12.0 0.0 0.49 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 GAP85862.1 - 0.13 12.2 0.4 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF952 PF06108.7 GAP85863.1 - 1.5e-16 60.0 0.0 1.9e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) DUF605 PF04652.11 GAP85866.1 - 0.36 10.1 21.1 0.41 9.9 14.6 1.0 1 0 0 1 1 1 0 Vta1 like SOBP PF15279.1 GAP85866.1 - 0.89 9.8 15.1 1 9.7 10.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Suf PF05843.9 GAP85866.1 - 1.5 8.4 15.2 1.9 8.1 10.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 GAP85866.1 - 2.3 6.3 31.0 2.6 6.1 21.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Phage_GPO PF05929.6 GAP85866.1 - 2.4 7.3 10.5 2.9 7.0 7.3 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Presenilin PF01080.12 GAP85866.1 - 6.3 5.5 10.4 6.9 5.3 7.2 1.0 1 0 0 1 1 1 0 Presenilin Asp-B-Hydro_N PF05279.6 GAP85866.1 - 8.1 6.2 9.1 9.4 6.0 6.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TFIIA PF03153.8 GAP85866.1 - 9.7 5.9 20.9 12 5.7 14.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Patatin PF01734.17 GAP85867.1 - 2.8e-09 37.2 0.0 4.6e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Glyco_hydro_92 PF07971.7 GAP85870.1 - 2.1e-171 571.0 0.5 2.6e-171 570.6 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Ribosomal_L7Ae PF01248.21 GAP85871.1 - 3.5e-18 64.9 0.4 1.3e-17 63.0 0.3 2.0 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1761 PF08570.5 GAP85872.1 - 4e-24 85.0 2.9 4.5e-24 84.8 2.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) NIF PF03031.13 GAP85873.1 - 1.1e-51 174.6 0.0 1.6e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF601 PF04642.7 GAP85873.1 - 1.3 8.3 6.8 1.9 7.7 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF601 tRNA-synt_1 PF00133.17 GAP85874.1 - 6.8e-203 674.9 0.0 1e-201 671.0 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 GAP85874.1 - 1e-29 103.2 0.0 3.2e-29 101.6 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 GAP85874.1 - 6.7e-18 64.5 0.1 7.9e-06 24.7 0.0 4.9 3 2 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 GAP85874.1 - 2e-13 50.0 3.1 4.6e-10 39.0 0.0 3.3 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 GAP85874.1 - 0.068 12.2 0.0 1 8.4 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DUF4415 PF14384.1 GAP85874.1 - 0.2 11.8 0.0 0.2 11.8 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4415) IF-2B PF01008.12 GAP85875.1 - 3.5e-41 141.0 0.0 5.2e-41 140.4 0.0 1.2 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF4646 PF15496.1 GAP85876.1 - 0.005 16.8 0.0 0.014 15.4 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) Zip PF02535.17 GAP85876.1 - 2.2 7.2 11.5 3.9 6.3 8.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Acetyltransf_1 PF00583.19 GAP85877.1 - 2.3e-13 49.9 0.1 4.9e-13 48.9 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAP85877.1 - 1.9e-07 30.7 0.0 3.8e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 GAP85877.1 - 0.00073 19.6 0.0 0.0016 18.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAP85877.1 - 0.0022 18.1 0.0 0.0036 17.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAP85877.1 - 0.018 14.8 0.1 0.037 13.8 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain adh_short PF00106.20 GAP85878.1 - 8.5e-30 103.8 0.0 1.5e-29 103.0 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP85878.1 - 2.9e-20 73.0 0.0 2.2e-19 70.1 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP85878.1 - 5.1e-14 52.3 0.0 7.7e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAP85878.1 - 0.0068 15.8 0.1 0.044 13.2 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAP85878.1 - 0.043 13.6 0.9 0.096 12.4 0.6 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 GAP85878.1 - 0.075 12.0 0.1 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Yae1_N PF09811.4 GAP85879.1 - 1e-08 34.5 7.8 3e-08 33.0 5.4 1.8 1 0 0 1 1 1 1 Essential protein Yae1, N terminal MoCo_carrier PF12694.2 GAP85879.1 - 0.029 13.8 0.3 0.046 13.1 0.2 1.3 1 0 0 1 1 1 0 Putative molybdenum carrier CI-B14_5a PF07347.7 GAP85880.1 - 0.13 12.0 0.0 0.83 9.4 0.0 2.2 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Band_7 PF01145.20 GAP85881.1 - 2.4e-25 89.4 6.1 2.7e-25 89.3 3.7 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF2884 PF11101.3 GAP85881.1 - 0.019 14.3 1.0 0.03 13.6 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Band_7_1 PF13421.1 GAP85881.1 - 0.038 13.4 0.1 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family RNase_T PF00929.19 GAP85882.1 - 2.6e-08 34.3 0.0 4.6e-07 30.2 0.0 2.3 1 1 0 1 1 1 1 Exonuclease BTK PF00779.14 GAP85882.1 - 1.9 8.1 5.6 0.32 10.6 0.9 2.0 2 0 0 2 2 2 0 BTK motif DUF676 PF05057.9 GAP85883.1 - 3.3e-53 180.2 0.0 4.7e-53 179.6 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 GAP85883.1 - 4.9e-07 29.6 0.0 1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 GAP85883.1 - 0.0016 18.0 0.0 0.0031 17.1 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 GAP85883.1 - 0.0016 18.0 0.0 0.0033 17.0 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 GAP85883.1 - 0.0017 18.2 0.1 0.0066 16.3 0.0 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 GAP85883.1 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 2) HhH-GPD PF00730.20 GAP85884.1 - 1.9e-15 57.0 0.0 3.6e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 GAP85884.1 - 2.3e-07 30.1 0.0 5.5e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Dicty_REP PF05086.7 GAP85884.1 - 0.19 9.4 7.0 0.35 8.5 4.9 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-AN1 PF01428.11 GAP85885.1 - 9.5e-12 44.5 12.5 1.4e-11 44.1 8.7 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger ADH_N PF08240.7 GAP85886.1 - 4.3e-28 97.2 2.1 1.3e-27 95.6 1.5 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAP85886.1 - 2.1e-19 69.3 1.5 4.1e-19 68.4 0.6 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 GAP85886.1 - 0.019 14.3 0.3 0.032 13.6 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF1188 PF06690.6 GAP85886.1 - 0.058 12.5 0.0 0.096 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Nucleopor_Nup85 PF07575.8 GAP85887.1 - 1.2e-06 27.0 0.0 4.8e-06 25.0 0.0 1.9 2 0 0 2 2 2 1 Nup85 Nucleoporin PBP1_TM PF14812.1 GAP85887.1 - 0.0069 16.6 5.5 0.0069 16.6 3.8 3.8 2 1 1 3 3 3 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Transthyretin PF00576.16 GAP85888.1 - 3.8e-27 94.3 1.2 4.6e-25 87.6 0.9 2.0 1 1 0 1 1 1 1 HIUase/Transthyretin family ArsA_ATPase PF02374.10 GAP85889.1 - 1.1e-111 372.7 0.1 1.3e-111 372.5 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 GAP85889.1 - 2.7e-17 62.8 0.3 1e-16 60.9 0.2 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 GAP85889.1 - 3.2e-09 36.9 0.2 3.6e-08 33.4 0.0 2.6 2 2 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 GAP85889.1 - 2.5e-06 26.8 0.0 8.5e-06 25.1 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 GAP85889.1 - 1.4e-05 24.6 0.0 0.0013 18.2 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 GAP85889.1 - 0.0014 18.1 0.0 0.0037 16.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAP85889.1 - 0.008 15.9 0.1 0.024 14.4 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain IstB_IS21 PF01695.12 GAP85889.1 - 0.019 14.4 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein MipZ PF09140.6 GAP85889.1 - 0.02 13.9 0.0 0.05 12.6 0.0 1.6 2 0 0 2 2 2 0 ATPase MipZ YhjQ PF06564.7 GAP85889.1 - 0.022 14.1 0.0 0.054 12.8 0.0 1.6 2 0 0 2 2 2 0 YhjQ protein AIP3 PF03915.8 GAP85889.1 - 0.04 12.8 0.1 0.058 12.2 0.1 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 DUF3502 PF12010.3 GAP85889.1 - 0.074 13.0 0.4 0.95 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3502) AAA_18 PF13238.1 GAP85889.1 - 0.14 12.4 0.0 0.39 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Amidohydro_2 PF04909.9 GAP85890.1 - 6.5e-22 78.3 0.0 7.8e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase DUF4328 PF14219.1 GAP85891.1 - 0.0072 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4328) DUF2029 PF09594.5 GAP85891.1 - 0.11 11.9 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) DUF1191 PF06697.7 GAP85891.1 - 0.12 11.1 0.0 0.23 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF4381 PF14316.1 GAP85891.1 - 0.14 12.2 0.0 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Herpes_gE PF02480.11 GAP85891.1 - 0.16 10.1 0.0 0.16 10.1 0.0 2.3 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein E Lipase_GDSL PF00657.17 GAP85893.1 - 2.6e-19 69.9 0.1 3.6e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 GAP85893.1 - 3.6e-17 63.0 0.7 4.9e-17 62.6 0.5 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 GAP85893.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Acetyltransf_10 PF13673.1 GAP85894.1 - 4.4e-10 39.6 0.3 8e-08 32.4 0.1 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAP85894.1 - 9e-05 22.4 0.0 0.00017 21.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 GAP85894.1 - 0.00033 20.5 0.2 0.0034 17.2 0.0 2.3 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAP85894.1 - 0.0012 18.9 0.0 0.003 17.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAP85894.1 - 0.027 14.2 0.0 0.067 12.9 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein COQ7 PF03232.8 GAP85895.1 - 2.4e-65 219.2 0.0 2.8e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 GAP85895.1 - 0.0028 17.9 0.0 0.0056 17.0 0.0 1.6 1 1 0 1 1 1 1 Rubrerythrin Plus-3 PF03126.13 GAP85896.1 - 1.8e-30 105.1 0.0 7.2e-30 103.2 0.0 2.0 2 0 0 2 2 2 1 Plus-3 domain Plasmodium_Vir PF05795.6 GAP85896.1 - 0.037 13.2 0.1 0.037 13.2 0.1 2.9 3 0 0 3 3 3 0 Plasmodium vivax Vir protein YebO PF13974.1 GAP85896.1 - 3.6 7.4 7.6 0.81 9.5 1.9 2.3 2 0 0 2 2 2 0 YebO-like protein Fungal_trans PF04082.13 GAP85897.1 - 6.4e-26 90.7 0.2 1.2e-25 89.9 0.1 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP85897.1 - 1.1e-07 31.6 9.6 2.5e-07 30.4 6.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_2 PF07992.9 GAP85898.1 - 1e-30 107.1 1.7 1.7e-30 106.4 1.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 GAP85898.1 - 5.9e-13 48.2 0.0 1.4e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 GAP85898.1 - 1.8e-12 47.5 1.4 3.4e-11 43.4 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP85898.1 - 5.5e-07 29.8 0.1 0.0086 16.1 0.0 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 GAP85898.1 - 2.4e-06 27.7 0.0 8.5e-06 25.9 0.0 2.0 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.1 GAP85898.1 - 0.00066 18.7 0.1 0.64 8.8 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HTH_41 PF14502.1 GAP85898.1 - 0.018 14.6 0.1 1.2 8.8 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain NAD_binding_9 PF13454.1 GAP85898.1 - 0.03 14.0 2.0 8.2 6.1 0.0 3.1 2 1 1 3 3 3 0 FAD-NAD(P)-binding TrkA_N PF02254.13 GAP85898.1 - 0.039 13.9 0.2 9.9 6.2 0.0 2.7 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_7 PF13241.1 GAP85898.1 - 0.097 12.9 0.5 3 8.1 0.0 2.9 3 0 0 3 3 3 0 Putative NAD(P)-binding Reo_sigmaC PF04582.7 GAP85899.1 - 0.11 11.6 2.0 0.24 10.5 1.4 1.6 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 GAP85899.1 - 0.15 11.8 32.1 0.022 14.5 17.3 2.7 2 1 0 2 2 2 0 Tropomyosin like Bacillus_HBL PF05791.6 GAP85899.1 - 0.16 11.3 8.2 3 7.1 1.2 2.9 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) IncA PF04156.9 GAP85899.1 - 0.38 10.3 39.9 0.39 10.2 6.5 3.8 3 1 1 4 4 4 0 IncA protein DivIVA PF05103.8 GAP85899.1 - 1.6 8.7 29.7 4.3 7.3 10.6 4.2 2 1 1 4 4 4 0 DivIVA protein Lectin_N PF03954.9 GAP85899.1 - 3 7.2 7.9 8.1 5.8 0.4 4.0 3 1 2 5 5 5 0 Hepatic lectin, N-terminal domain PLDc PF00614.17 GAP85900.1 - 1.8e-17 62.4 1.1 6.7e-08 32.0 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 GAP85900.1 - 2e-13 50.1 0.0 1.9e-07 30.8 0.0 2.8 2 1 0 2 2 2 2 PLD-like domain PX PF00787.19 GAP85900.1 - 6.4e-09 35.6 0.0 4.1e-08 32.9 0.0 2.4 1 1 0 1 1 1 1 PX domain MFS_1 PF07690.11 GAP85901.1 - 7.1e-27 94.0 50.9 2.9e-26 92.0 12.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRP PF06011.7 GAP85902.1 - 1.3e-82 277.7 24.6 6.3e-82 275.4 17.1 1.8 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 GAP85902.1 - 5.4e-16 58.9 0.0 9.8e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 ML-like domain Strabismus PF06638.6 GAP85902.1 - 0.47 8.7 0.8 0.73 8.0 0.6 1.2 1 0 0 1 1 1 0 Strabismus protein Cys_Met_Meta_PP PF01053.15 GAP85903.1 - 1.5e-55 188.1 0.0 3e-55 187.0 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 GAP85903.1 - 0.014 14.1 0.0 0.021 13.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V WBS_methylT PF12589.3 GAP85904.1 - 1.8e-16 60.3 4.6 3.2e-16 59.5 3.2 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 GAP85904.1 - 5.6e-11 42.7 0.0 1e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP85904.1 - 3.5e-07 30.5 0.0 7.6e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP85904.1 - 5.4e-06 26.0 0.0 8.8e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP85904.1 - 2.8e-05 23.9 0.0 3.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 GAP85904.1 - 0.00016 21.2 0.0 0.00033 20.2 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 GAP85904.1 - 0.00031 20.7 0.0 0.00084 19.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP85904.1 - 0.00034 21.0 0.0 0.00096 19.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP85904.1 - 0.00082 19.9 0.0 0.0016 18.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 GAP85904.1 - 0.0089 15.1 0.0 0.11 11.5 0.0 2.0 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 GAP85904.1 - 0.049 12.7 0.0 0.12 11.4 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Erv26 PF04148.8 GAP85905.1 - 1.8e-86 288.8 4.2 2.1e-86 288.6 2.9 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF3377 PF11857.3 GAP85905.1 - 0.011 15.3 0.0 0.037 13.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Cytochrom_C_asm PF01578.15 GAP85905.1 - 0.016 14.7 2.4 0.016 14.7 1.6 1.9 2 1 0 2 2 2 0 Cytochrome C assembly protein Pox_A9 PF04835.7 GAP85905.1 - 0.15 11.9 2.7 0.23 11.3 0.4 2.3 2 0 0 2 2 2 0 A9 protein conserved region RNase_T PF00929.19 GAP85906.1 - 4.3e-18 66.1 0.0 7e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Exonuclease MCM PF00493.18 GAP85907.1 - 5.5e-136 452.7 1.1 8.4e-136 452.1 0.7 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 GAP85907.1 - 1.3e-21 77.3 1.4 1.3e-20 74.1 0.0 2.7 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 GAP85907.1 - 8.9e-08 31.5 0.0 9.1e-07 28.2 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 GAP85907.1 - 0.00078 18.9 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 GAP85907.1 - 0.0012 18.4 0.0 0.0035 16.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAP85907.1 - 0.025 14.3 0.0 0.14 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2360 PF10152.4 GAP85907.1 - 9.6 6.4 15.7 2.2 8.5 0.0 4.0 4 1 0 4 4 4 0 Predicted coiled-coil domain-containing protein (DUF2360) F1F0-ATPsyn_F PF10791.4 GAP85909.1 - 1.2e-40 137.6 0.3 1.3e-40 137.5 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi ETC_C1_NDUFA4 PF04800.7 GAP85910.1 - 1.2e-37 127.7 0.5 2e-37 127.1 0.4 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region CLTH PF10607.4 GAP85911.1 - 3e-35 121.0 2.5 4.3e-35 120.5 1.7 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 GAP85911.1 - 2e-08 33.7 0.1 1.3e-07 31.1 0.0 2.3 2 0 0 2 2 2 1 LisH TPR_20 PF14561.1 GAP85911.1 - 0.13 12.4 1.2 0.4 10.8 0.2 2.2 2 1 0 2 2 2 0 Tetratricopeptide repeat PRK PF00485.13 GAP85912.1 - 5.2e-58 195.8 0.0 7.2e-58 195.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 GAP85912.1 - 8.9e-38 129.5 0.0 1.3e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 GAP85912.1 - 1.3e-09 38.9 0.0 2.9e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAP85912.1 - 9.2e-06 25.9 0.0 2.1e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 GAP85912.1 - 0.00012 21.7 0.0 0.00023 20.8 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 GAP85912.1 - 0.00027 20.8 0.1 0.0015 18.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 GAP85912.1 - 0.0028 17.9 0.3 0.014 15.6 0.1 2.0 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 GAP85912.1 - 0.0046 16.4 0.4 0.012 15.1 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 GAP85912.1 - 0.026 13.5 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 GAP85912.1 - 0.034 14.1 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.12 GAP85912.1 - 0.04 13.7 0.0 0.084 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 MobB PF03205.9 GAP85912.1 - 0.046 13.4 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 GAP85912.1 - 0.065 12.4 0.0 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 GAP85912.1 - 0.066 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.1 GAP85912.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 GAP85912.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Abhydrolase_6 PF12697.2 GAP85913.1 - 1.6e-19 70.7 0.7 2e-19 70.3 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP85913.1 - 1.4e-09 37.8 0.0 1.6e-09 37.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 GAP85913.1 - 0.0065 15.9 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase DUF900 PF05990.7 GAP85913.1 - 0.085 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.8 GAP85913.1 - 0.13 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein BAR_2 PF10455.4 GAP85914.1 - 5.9e-60 202.6 0.5 8.3e-60 202.1 0.3 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 GAP85914.1 - 1.2e-20 74.0 1.1 9.7e-20 71.0 0.8 1.9 1 1 0 1 1 1 1 BAR domain MCPVI PF02993.9 GAP85914.1 - 4.9 7.2 9.1 19 5.2 3.3 2.8 1 1 1 2 2 2 0 Minor capsid protein VI ETC_C1_NDUFA5 PF04716.9 GAP85915.1 - 3.1e-20 71.4 1.5 3.8e-19 67.9 0.1 2.5 2 0 0 2 2 2 2 ETC complex I subunit conserved region RNA_pol_I_TF PF04090.7 GAP85916.1 - 3e-09 36.4 0.0 4e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase I specific initiation factor Yip1 PF04893.12 GAP85917.1 - 0.0005 19.6 0.8 0.00066 19.2 0.5 1.3 1 1 0 1 1 1 1 Yip1 domain PAS_9 PF13426.1 GAP85918.1 - 0.00036 20.8 0.0 0.00074 19.8 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 GAP85918.1 - 0.037 13.8 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 PAS fold DUF3439 PF11921.3 GAP85919.1 - 0.42 10.3 6.7 0.85 9.3 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 GAP85919.1 - 0.67 7.8 7.0 0.92 7.4 4.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 LysM PF01476.15 GAP85920.1 - 1.1e-20 73.2 2.2 4.6e-07 29.6 0.1 6.7 7 0 0 7 7 7 5 LysM domain Sporozoite_P67 PF05642.6 GAP85920.1 - 5.1 4.8 6.8 11 3.7 4.7 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glyco_hydro_18 PF00704.23 GAP85921.1 - 1.3e-80 271.4 4.1 1.9e-80 270.9 2.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 GAP85921.1 - 2.5e-09 36.9 12.2 2.5e-09 36.9 8.5 3.9 3 0 0 3 3 3 1 Chitin recognition protein zf-C2H2 PF00096.21 GAP85922.1 - 1.2e-12 47.3 11.4 2.5e-06 27.4 0.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP85922.1 - 2.6e-10 39.8 10.5 0.00012 22.1 3.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAP85922.1 - 1.7e-07 31.1 12.1 3e-06 27.2 3.0 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 GAP85922.1 - 1.8e-06 27.8 5.6 0.00034 20.6 0.7 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAP85922.1 - 2.6e-05 24.2 9.6 4.5e-05 23.4 0.2 3.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 GAP85922.1 - 0.0066 16.3 8.2 0.02 14.7 0.2 2.8 2 1 0 2 2 2 1 C2H2-type zinc finger zf-BED PF02892.10 GAP85922.1 - 2.1 8.2 7.5 1.5 8.6 1.4 2.4 1 1 1 2 2 2 0 BED zinc finger Elf1 PF05129.8 GAP85922.1 - 2.6 7.8 5.5 49 3.7 3.8 2.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-C2HC_2 PF13913.1 GAP85922.1 - 5.4 6.7 7.8 6.4 6.5 1.6 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type ATP_bind_4 PF01902.12 GAP85923.1 - 2.4e-18 66.3 0.0 7e-07 28.8 0.0 3.9 4 0 0 4 4 4 3 ATP-binding region Ribonuc_L-PSP PF01042.16 GAP85923.1 - 3.5e-05 23.5 0.0 0.0017 18.1 0.0 3.2 4 0 0 4 4 4 1 Endoribonuclease L-PSP Trypan_PARP PF05887.6 GAP85923.1 - 0.18 11.6 4.3 0.068 12.9 0.9 1.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Polysacc_lyase PF14099.1 GAP85924.1 - 6.1e-46 156.8 9.3 7.1e-46 156.6 6.4 1.0 1 0 0 1 1 1 1 Polysaccharide lyase Triabin PF03973.8 GAP85924.1 - 0.031 13.9 0.1 0.055 13.1 0.1 1.4 1 0 0 1 1 1 0 Triabin Laminin_G_2 PF02210.19 GAP85924.1 - 0.035 14.1 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 Laminin G domain Tim17 PF02466.14 GAP85925.1 - 7e-28 97.2 0.6 1.2e-27 96.4 0.4 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family CAP59_mtransfer PF11735.3 GAP85926.1 - 2.1e-75 253.0 0.0 2.8e-75 252.6 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Methyltransf_11 PF08241.7 GAP85927.1 - 1.4e-11 44.7 0.0 2.3e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP85927.1 - 2.4e-07 30.5 0.0 4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP85927.1 - 0.00015 20.9 0.0 0.00023 20.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 GAP85927.1 - 0.00017 21.2 0.0 0.0014 18.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP85927.1 - 0.00019 21.8 0.0 0.00033 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP85927.1 - 0.00071 20.1 0.0 0.002 18.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP85927.1 - 0.0012 18.9 0.0 0.062 13.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 GAP85927.1 - 0.018 14.4 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_8 PF05148.10 GAP85927.1 - 0.023 14.3 0.0 0.062 12.9 0.0 1.7 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_25 PF13649.1 GAP85927.1 - 0.027 14.8 0.0 0.051 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 GAP85927.1 - 0.13 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase LSM PF01423.17 GAP85928.1 - 2.2e-19 68.7 0.2 3e-19 68.3 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 GAP85928.1 - 0.00031 20.5 0.2 0.00039 20.2 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.2 GAP85928.1 - 0.039 13.7 0.1 0.047 13.5 0.1 1.1 1 0 0 1 1 1 0 Scd6-like Sm domain IceA2 PF05862.6 GAP85928.1 - 0.058 13.1 1.5 0.11 12.1 0.1 2.0 1 1 1 2 2 2 0 Helicobacter pylori IceA2 protein Rad60-SLD PF11976.3 GAP85929.1 - 1e-10 41.1 0.2 3.3e-10 39.4 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Cellulase PF00150.13 GAP85930.1 - 1.1e-39 136.3 0.1 1.3e-39 136.1 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ribonucleas_3_3 PF14622.1 GAP85931.1 - 1.5e-11 44.3 0.0 2e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 GAP85931.1 - 7.1e-09 36.1 0.0 2e-08 34.6 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease III domain Kdo PF06293.9 GAP85932.1 - 2.3e-05 23.5 0.0 4.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAP85932.1 - 0.00033 20.4 0.6 0.0012 18.5 0.4 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 GAP85932.1 - 0.0033 16.8 0.1 0.007 15.7 0.0 1.5 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.20 GAP85932.1 - 0.0047 16.1 0.3 0.0076 15.4 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 GAP85932.1 - 0.0092 15.5 0.1 1.7 8.1 0.2 2.2 1 1 1 2 2 2 2 Choline/ethanolamine kinase WaaY PF06176.6 GAP85932.1 - 0.032 13.4 0.0 0.064 12.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) 7tm_2 PF00002.19 GAP85933.1 - 5.4e-06 25.6 7.3 5.4e-06 25.6 5.0 1.8 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 GAP85933.1 - 2e-05 23.6 3.2 3.8e-05 22.7 2.2 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor HET PF06985.6 GAP85934.1 - 1.6e-16 60.7 0.4 1.6e-16 60.7 0.3 2.3 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) YqfQ PF14181.1 GAP85934.1 - 2.5 8.1 5.6 4.1 7.4 3.9 1.3 1 0 0 1 1 1 0 YqfQ-like protein DEAD PF00270.24 GAP85935.1 - 1.8e-20 73.1 0.0 1.2e-19 70.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP85935.1 - 3.7e-20 71.5 0.1 1.1e-19 70.0 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAP85935.1 - 4.1e-20 72.3 0.0 1.1e-19 71.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 GAP85935.1 - 6.5e-05 23.0 0.0 0.00022 21.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain ART PF01129.13 GAP85935.1 - 0.017 14.2 0.0 0.2 10.7 0.0 2.1 1 1 1 2 2 2 0 NAD:arginine ADP-ribosyltransferase TAP_C PF03943.8 GAP85936.1 - 7.5e-15 54.0 0.3 1.4e-14 53.1 0.2 1.5 1 0 0 1 1 1 1 TAP C-terminal domain UBA_4 PF14555.1 GAP85936.1 - 2.1e-06 27.1 0.1 1.7e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 UBA-like domain LRR_4 PF12799.2 GAP85936.1 - 0.0002 20.8 4.3 0.0033 17.0 0.2 2.9 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) NTF2 PF02136.15 GAP85936.1 - 0.0055 17.0 0.1 0.035 14.4 0.0 2.4 2 1 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.1 GAP85936.1 - 0.063 13.0 0.1 0.19 11.4 0.1 1.8 1 0 0 1 1 1 0 Leucine rich repeat LRR_6 PF13516.1 GAP85936.1 - 0.17 12.0 1.8 12 6.3 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeat Kelch_6 PF13964.1 GAP85937.1 - 0.00091 19.3 3.3 0.03 14.4 0.0 4.0 4 0 0 4 4 4 1 Kelch motif Rifin_STEVOR PF02009.11 GAP85937.1 - 0.017 14.8 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family STE2 PF02116.10 GAP85937.1 - 0.054 12.5 0.1 0.094 11.7 0.1 1.3 1 0 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR TMEM154 PF15102.1 GAP85937.1 - 0.067 12.8 0.2 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family MtrF PF09472.5 GAP85937.1 - 0.18 11.1 3.7 0.38 10.0 2.5 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) TMEM51 PF15345.1 GAP85937.1 - 1.6 8.4 6.3 12 5.5 0.6 2.5 1 1 0 2 2 2 0 Transmembrane protein 51 MSC PF09402.5 GAP85938.1 - 7.5e-87 291.1 0.2 1.3e-85 287.1 0.1 2.0 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 GAP85938.1 - 1.8e-15 56.1 0.0 3e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 HeH/LEM domain Thymopoietin PF08198.6 GAP85938.1 - 0.016 14.6 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Thymopoietin protein DUF3350 PF11830.3 GAP85938.1 - 0.039 13.9 0.3 11 6.1 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3350) HLH PF00010.21 GAP85939.1 - 1.2e-17 63.3 0.0 4.5e-17 61.4 0.0 2.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Exonuc_VII_L PF02601.10 GAP85939.1 - 0.0012 18.1 7.1 0.0012 18.1 4.9 1.9 2 0 0 2 2 2 1 Exonuclease VII, large subunit Spt20 PF12090.3 GAP85939.1 - 0.47 9.7 14.1 0.054 12.8 6.6 1.7 2 0 0 2 2 2 0 Spt20 family DUF4557 PF15101.1 GAP85939.1 - 2.7 7.7 17.7 8 6.2 12.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) IncA PF04156.9 GAP85939.1 - 7.2 6.1 25.7 9.2 5.8 14.4 2.5 2 0 0 2 2 2 0 IncA protein SHR3_chaperone PF08229.6 GAP85940.1 - 3.2e-71 238.3 0.0 3.6e-71 238.1 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF3899 PF13038.1 GAP85940.1 - 6.2 7.0 0.0 6.2 7.0 0.0 3.4 3 2 1 4 4 4 0 Domain of unknown function (DUF3899) Alpha_GJ PF03229.8 GAP85941.1 - 3.5e-05 24.1 9.3 3.5e-05 24.1 6.4 2.2 2 0 0 2 2 2 1 Alphavirus glycoprotein J Granulin PF00396.13 GAP85941.1 - 9.1 6.4 29.5 0.43 10.7 4.4 3.6 2 1 1 3 3 3 0 Granulin HAD_2 PF13419.1 GAP85942.1 - 6.6e-29 101.3 0.2 3.3e-28 99.0 0.1 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAP85942.1 - 1.3e-07 31.1 0.0 2.9e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 GAP85942.1 - 0.0066 16.8 0.0 0.029 14.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Fungal_trans_2 PF11951.3 GAP85943.1 - 3e-77 259.7 1.2 3.9e-77 259.4 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain SAM_1 PF00536.25 GAP85944.1 - 3.6e-06 27.0 0.1 2.1e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 GAP85944.1 - 1e-05 25.2 0.0 2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 GAP85944.1 - 0.00043 20.4 0.1 0.0017 18.4 0.1 2.0 1 1 0 1 1 1 1 PH domain PH_9 PF15410.1 GAP85944.1 - 0.19 11.9 0.0 0.44 10.7 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Sod_Fe_C PF02777.13 GAP85945.1 - 2.3e-16 59.5 0.0 2.5e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain CLAMP PF14769.1 GAP85945.1 - 0.1 12.7 0.2 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Flagellar C1a complex subunit C1a-32 Mito_carr PF00153.22 GAP85947.1 - 4e-63 209.1 0.8 8.4e-21 73.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ApoO PF09769.4 GAP85948.1 - 1.7e-45 154.5 0.1 4.6e-45 153.1 0.0 1.7 2 0 0 2 2 2 1 Apolipoprotein O Peptidase_M3 PF01432.15 GAP85949.1 - 6.3e-127 424.3 0.1 9.9e-127 423.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M3 DNA_pack_N PF02500.10 GAP85949.1 - 0.066 12.7 2.8 0.79 9.2 0.1 3.1 3 0 0 3 3 3 0 Probable DNA packing protein, N-terminus Peptidase_M50B PF13398.1 GAP85949.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like WSC PF01822.14 GAP85950.1 - 1.9e-16 59.7 2.7 1.9e-16 59.7 1.9 1.9 2 0 0 2 2 2 1 WSC domain IMS PF00817.15 GAP85951.1 - 1.4e-38 132.0 0.0 2.6e-38 131.1 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 GAP85951.1 - 2.7e-18 66.1 0.0 6.3e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 GAP85951.1 - 2.1e-13 50.0 7.6 4.7e-07 29.6 1.1 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF4414) IMS_HHH PF11798.3 GAP85951.1 - 6.5e-05 22.7 0.3 0.00032 20.5 0.0 2.4 2 0 0 2 2 2 1 IMS family HHH motif MgtE_N PF03448.12 GAP85951.1 - 0.018 15.3 0.8 0.79 10.0 0.0 3.2 2 1 0 2 2 2 0 MgtE intracellular N domain BRCT PF00533.21 GAP85951.1 - 0.027 14.6 0.0 0.07 13.2 0.0 1.8 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 GAP85951.1 - 0.066 13.0 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain HHH_5 PF14520.1 GAP85951.1 - 0.12 12.5 0.0 0.35 11.0 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain RED_N PF07808.8 GAP85952.1 - 1.1e-07 31.3 6.7 1.1e-07 31.3 4.6 2.5 3 0 0 3 3 3 1 RED-like protein N-terminal region IU_nuc_hydro PF01156.14 GAP85953.1 - 1.1e-20 74.1 0.0 1.2e-20 73.9 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase IU_nuc_hydro PF01156.14 GAP85954.1 - 9.2e-14 51.3 0.0 1.1e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Mago-bind PF09282.5 GAP85955.1 - 3.1e-12 45.8 2.4 8.2e-12 44.4 1.7 1.8 1 0 0 1 1 1 1 Mago binding RR_TM4-6 PF06459.7 GAP85955.1 - 3.4 7.4 12.8 7.5 6.3 8.9 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 zf-UBR PF02207.15 GAP85956.1 - 4.6e-18 64.6 15.7 1.1e-17 63.4 10.9 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 GAP85956.1 - 2.5e-05 23.8 0.0 6.2e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS WD40 PF00400.27 GAP85957.1 - 6.5e-57 187.5 15.3 4.6e-11 42.1 0.1 7.6 7 1 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 GAP85957.1 - 2.3e-06 27.4 0.0 0.0069 16.1 0.0 3.6 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 GAP85957.1 - 5.6e-06 24.7 1.2 0.0077 14.4 0.0 3.8 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAP85957.1 - 0.002 16.9 0.1 0.4 9.3 0.0 3.5 1 1 1 3 3 3 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 GAP85957.1 - 0.017 13.4 0.0 0.1 10.8 0.0 2.2 1 1 1 2 2 2 0 Cytochrome D1 heme domain VID27 PF08553.5 GAP85957.1 - 0.069 11.3 0.1 7.8 4.5 0.0 3.0 2 1 1 3 3 3 0 VID27 cytoplasmic protein BBS2_Mid PF14783.1 GAP85957.1 - 0.081 12.7 0.0 1.4 8.7 0.0 2.5 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region PD40 PF07676.7 GAP85957.1 - 0.23 11.1 7.4 13 5.5 0.0 5.0 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 GAP85957.1 - 0.26 9.4 0.0 0.77 7.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) DUF605 PF04652.11 GAP85957.1 - 8.7 5.6 17.3 12 5.1 12.0 1.2 1 0 0 1 1 1 0 Vta1 like Exo_endo_phos PF03372.18 GAP85958.1 - 7.5e-16 58.8 0.1 1.2e-15 58.1 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.20 GAP85959.1 - 3.3e-51 173.9 0.0 7.9e-32 110.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAP85959.1 - 8.9e-26 90.4 0.0 4e-17 62.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase CDV3 PF15359.1 GAP85959.1 - 0.072 13.1 0.3 0.072 13.1 0.2 2.2 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 CENP-B_dimeris PF09026.5 GAP85959.1 - 4 7.7 13.5 11 6.3 9.3 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FKBP_C PF00254.23 GAP85960.1 - 3.5e-31 107.0 0.1 1.5e-30 105.0 0.0 2.1 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4066 PF13278.1 GAP85961.1 - 6.7e-09 35.2 0.0 1.1e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 GAP85961.1 - 4.1e-06 26.3 0.0 6e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Glyco_trans_2_3 PF13632.1 GAP85962.1 - 2.2e-19 69.9 0.1 2.2e-19 69.9 0.1 1.7 2 0 0 2 2 2 1 Glycosyl transferase family group 2 FimP PF09766.4 GAP85963.1 - 2.5e-27 95.8 11.6 3e-27 95.6 8.0 1.1 1 0 0 1 1 1 1 Fms-interacting protein K-box PF01486.12 GAP85963.1 - 0.0061 16.3 1.3 0.0061 16.3 0.9 3.0 2 2 1 3 3 3 1 K-box region DUF87 PF01935.12 GAP85963.1 - 0.077 12.7 2.1 0.1 12.4 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 CENP-F_leu_zip PF10473.4 GAP85963.1 - 0.19 11.6 13.2 1.4 8.7 3.8 2.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.1 GAP85963.1 - 3.8 7.4 14.6 1.5 8.7 1.8 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Pinin_SDK_memA PF04696.8 GAP85963.1 - 5.7 6.5 13.1 2.6 7.6 3.6 2.3 2 1 0 2 2 2 0 pinin/SDK/memA/ protein conserved region HlyIII PF03006.15 GAP85964.1 - 4.1e-59 199.6 20.0 5.8e-59 199.1 13.9 1.2 1 0 0 1 1 1 1 Haemolysin-III related DUF373 PF04123.8 GAP85964.1 - 0.19 10.6 2.4 0.41 9.6 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF373) RabGAP-TBC PF00566.13 GAP85965.1 - 5.7e-31 107.6 0.0 6.6e-26 91.1 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Sulfate_transp PF00916.15 GAP85966.1 - 2.3e-75 253.1 11.1 4.5e-75 252.2 7.7 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 GAP85966.1 - 1.5e-29 101.4 4.4 1.5e-29 101.4 3.0 3.8 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 GAP85966.1 - 7.8e-07 28.5 0.0 1.6e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain Ycf66_N PF07444.6 GAP85966.1 - 6.1 6.6 11.5 1.5 8.5 0.1 3.0 3 0 0 3 3 3 0 Ycf66 protein N-terminus Pkinase PF00069.20 GAP85968.1 - 9.9e-09 34.7 0.1 3.2e-08 33.0 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP85968.1 - 1.2e-06 27.7 0.1 7.5e-05 21.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Zn_clus PF00172.13 GAP85969.1 - 4.2 7.3 13.2 0.057 13.3 3.7 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.11 GAP85970.1 - 1.9e-16 60.5 0.3 2.7e-16 60.0 0.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 GAP85970.1 - 0.036 12.9 0.1 0.054 12.3 0.1 1.1 1 0 0 1 1 1 0 CsiD Fungal_trans PF04082.13 GAP85971.1 - 3.2e-43 147.4 0.1 6.4e-43 146.5 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP85971.1 - 1.6e-08 34.3 5.7 3e-08 33.4 4.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 GAP85972.1 - 8.4e-39 133.2 23.9 8.4e-39 133.2 16.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP85972.1 - 5e-12 45.1 5.1 5e-12 45.1 3.6 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 GAP85972.1 - 0.00037 18.8 0.8 0.00065 18.0 0.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 GAP85972.1 - 0.038 12.0 0.1 0.073 11.1 0.1 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family S4 PF01479.20 GAP85973.1 - 5.7e-15 54.4 0.0 1.1e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 GAP85973.1 - 0.14 11.7 0.0 0.39 10.3 0.0 1.7 1 0 0 1 1 1 0 S4 domain Septin PF00735.13 GAP85974.1 - 1.4e-122 408.1 0.2 1.4e-122 408.1 0.1 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 GAP85974.1 - 3.1e-07 30.3 0.0 8.8e-07 28.8 0.0 1.8 2 0 0 2 2 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 GAP85974.1 - 9.2e-05 21.6 0.4 0.00071 18.8 0.3 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 GAP85974.1 - 0.00018 21.7 2.3 0.025 14.8 0.0 2.7 3 0 0 3 3 3 1 ABC transporter GTP_EFTU PF00009.22 GAP85974.1 - 0.00096 18.6 2.0 0.0053 16.2 0.0 2.9 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 GAP85974.1 - 0.0015 18.0 2.6 0.0042 16.5 1.7 1.9 1 1 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 GAP85974.1 - 0.0029 17.6 0.1 0.016 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 GAP85974.1 - 0.0038 17.6 0.0 0.017 15.5 0.0 2.2 2 0 0 2 2 1 1 Miro-like protein FtsK_SpoIIIE PF01580.13 GAP85974.1 - 0.0059 16.1 0.0 0.028 13.9 0.0 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family AIG1 PF04548.11 GAP85974.1 - 0.0061 15.7 2.6 0.0079 15.3 0.0 2.4 3 0 0 3 3 3 1 AIG1 family AAA_22 PF13401.1 GAP85974.1 - 0.0062 16.6 0.0 0.044 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 GAP85974.1 - 0.009 15.5 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Dynamin_N PF00350.18 GAP85974.1 - 0.013 15.3 4.9 0.75 9.5 0.0 3.4 3 0 0 3 3 3 0 Dynamin family Ras PF00071.17 GAP85974.1 - 0.014 14.8 0.1 0.058 12.7 0.0 2.1 3 0 0 3 3 3 0 Ras family RNA_helicase PF00910.17 GAP85974.1 - 0.091 12.9 0.7 0.67 10.1 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.1 GAP85974.1 - 0.095 12.2 0.7 0.18 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 GAP85974.1 - 0.15 11.7 1.6 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Exonuc_VII_L PF02601.10 GAP85974.1 - 0.15 11.2 5.9 0.26 10.4 4.1 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Strep_SA_rep PF06696.6 GAP85974.1 - 0.32 10.8 1.9 0.36 10.6 0.1 1.9 2 0 0 2 2 2 0 Streptococcal surface antigen repeat AAA_32 PF13654.1 GAP85974.1 - 0.34 9.5 11.7 0.56 8.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Phage_GPO PF05929.6 GAP85974.1 - 1.4 8.1 7.0 2.2 7.4 4.9 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase IncA PF04156.9 GAP85974.1 - 4.6 6.8 8.4 7.2 6.1 5.8 1.3 1 0 0 1 1 1 0 IncA protein PPR_2 PF13041.1 GAP85977.1 - 6.7e-08 32.3 0.0 0.039 13.9 0.0 5.0 5 0 0 5 5 5 2 PPR repeat family PPR_3 PF13812.1 GAP85977.1 - 2.3e-07 30.5 3.5 0.053 13.8 0.1 6.7 8 0 0 8 8 8 2 Pentatricopeptide repeat domain PPR PF01535.15 GAP85977.1 - 7.8e-06 25.5 0.9 0.24 11.4 0.0 4.8 5 0 0 5 5 5 2 PPR repeat LSM PF01423.17 GAP85978.1 - 1.5e-16 59.6 0.0 2e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain SAP18 PF06487.7 GAP85978.1 - 0.14 12.0 0.0 0.28 10.9 0.0 1.5 1 1 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) Zn_clus PF00172.13 GAP85980.1 - 9.8e-09 34.9 9.3 2e-08 33.9 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ku PF02735.11 GAP85981.1 - 2.1e-36 125.2 0.0 3.4e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 GAP85981.1 - 5.9e-25 88.0 0.0 9.3e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain SAP PF02037.22 GAP85981.1 - 2.8e-11 42.6 0.7 5.7e-11 41.6 0.5 1.6 1 0 0 1 1 1 1 SAP domain Ku_C PF03730.9 GAP85981.1 - 4.8e-09 36.6 0.0 1.5e-08 35.0 0.0 1.9 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm LETM1 PF07766.8 GAP85981.1 - 0.00058 18.9 0.1 0.00096 18.2 0.0 1.2 1 0 0 1 1 1 1 LETM1-like protein VWA_2 PF13519.1 GAP85981.1 - 0.014 15.4 0.0 0.053 13.6 0.0 1.9 1 1 0 2 2 2 0 von Willebrand factor type A domain Complex1_51K PF01512.12 GAP85981.1 - 0.085 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit Ferrochelatase PF00762.14 GAP85982.1 - 1.1e-92 310.4 0.0 1.3e-92 310.2 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase MFS_1 PF07690.11 GAP85983.1 - 6.7e-23 80.9 35.3 2.8e-18 65.7 14.5 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Glyco_trans_2_3 PF13632.1 GAP85983.1 - 0.19 11.4 0.1 0.19 11.4 0.1 2.5 2 0 0 2 2 2 0 Glycosyl transferase family group 2 OATP PF03137.15 GAP85983.1 - 0.22 9.5 2.8 0.57 8.1 1.0 2.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family YajC PF02699.10 GAP85983.1 - 0.73 9.5 3.0 10 5.9 0.2 2.6 2 0 0 2 2 2 0 Preprotein translocase subunit Ank_2 PF12796.2 GAP85984.1 - 1.8e-14 53.8 0.1 2.7e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAP85984.1 - 4.3e-14 51.5 1.0 9e-09 34.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 GAP85984.1 - 2.8e-10 40.4 0.1 4.8e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP85984.1 - 5.4e-10 39.1 0.2 1e-07 31.9 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP85984.1 - 1.7e-09 36.9 0.3 7.4e-07 28.8 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat bZIP_1 PF00170.16 GAP85984.1 - 0.0013 18.6 7.4 0.0022 17.9 5.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor HR1 PF02185.11 GAP85984.1 - 0.043 13.5 1.5 0.13 11.9 1.0 1.8 2 0 0 2 2 2 0 Hr1 repeat SLA_LP_auto_ag PF05889.8 GAP85984.1 - 0.17 10.3 0.0 0.23 9.8 0.0 1.1 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) bZIP_Maf PF03131.12 GAP85984.1 - 5 7.4 12.3 0.2 11.9 4.3 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor Lipase_GDSL_2 PF13472.1 GAP85985.1 - 3.2e-20 73.0 2.1 4.7e-20 72.4 1.5 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Amidohydro_1 PF01979.15 GAP85986.1 - 4.9e-43 148.0 0.0 6e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 GAP85986.1 - 2.6e-06 27.1 0.0 7.5e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 GAP85986.1 - 3.4e-06 26.5 1.1 0.0022 17.3 0.0 3.3 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 GAP85986.1 - 0.00015 21.9 1.5 0.0073 16.3 1.0 2.8 1 1 0 1 1 1 1 Amidohydrolase Acyl_transf_1 PF00698.16 GAP85987.1 - 7e-79 265.4 0.0 1e-76 258.3 0.0 3.1 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 GAP85987.1 - 1.2e-38 131.2 0.0 2.9e-38 130.0 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 GAP85987.1 - 1.9e-31 107.5 0.3 7.4e-31 105.7 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 GAP85987.1 - 1.5e-20 73.3 0.0 5e-20 71.6 0.0 2.0 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.10 GAP85987.1 - 0.00042 19.5 0.1 0.017 14.2 0.1 2.4 2 0 0 2 2 2 1 Nitronate monooxygenase PCIF1_WW PF12237.3 GAP85987.1 - 0.043 13.0 0.0 0.2 10.9 0.0 1.9 2 0 0 2 2 2 0 Phosphorylated CTD interacting factor 1 WW domain ketoacyl-synt PF00109.21 GAP85988.1 - 2.9e-19 69.5 0.0 6.8e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 GAP85988.1 - 3.7e-19 69.4 0.0 1.2e-18 67.7 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ACPS PF01648.15 GAP85988.1 - 9.3e-19 67.3 0.0 2.2e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 GAP85988.1 - 7.6e-10 38.6 0.0 1.8e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 GAP85988.1 - 2.4e-05 24.3 0.0 0.00013 21.8 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAP85988.1 - 0.0023 17.6 0.0 0.032 13.8 0.0 2.6 2 0 0 2 2 2 1 KR domain AA_permease_2 PF13520.1 GAP85989.1 - 2.9e-73 246.8 41.6 3.5e-73 246.5 28.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAP85989.1 - 5.7e-20 71.0 33.3 7.1e-20 70.7 23.1 1.1 1 0 0 1 1 1 1 Amino acid permease Lipoxygenase PF00305.14 GAP85990.1 - 5.2e-17 61.1 0.0 1.1e-07 30.3 0.0 2.1 2 0 0 2 2 2 2 Lipoxygenase Zn_clus PF00172.13 GAP85991.1 - 2.3e-08 33.8 8.2 3.7e-08 33.1 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDE_C PF04880.8 GAP85991.1 - 2.5 8.4 6.7 0.46 10.8 0.9 2.1 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Clr5 PF14420.1 GAP85992.1 - 4.2e-10 39.3 0.3 7.8e-10 38.5 0.2 1.3 1 0 0 1 1 1 1 Clr5 domain Phage_NinH PF06322.6 GAP85992.1 - 0.084 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Phage NinH protein Adeno_E3_14_5 PF04834.7 GAP85993.1 - 0.19 12.1 5.1 1.5 9.2 0.2 3.0 3 0 0 3 3 3 0 Early E3 14.5 kDa protein WD40 PF00400.27 GAP85995.1 - 0.03 14.2 6.7 1.5 8.8 0.5 4.6 4 0 0 4 4 4 0 WD domain, G-beta repeat PQ-loop PF04193.9 GAP85996.1 - 3.7e-19 68.0 9.7 1.2e-12 47.1 0.9 2.7 2 0 0 2 2 2 2 PQ loop repeat DUF1469 PF07332.6 GAP85996.1 - 0.00092 18.9 2.2 0.00092 18.9 1.5 3.3 1 1 2 3 3 3 1 Protein of unknown function (DUF1469) DUF4131 PF13567.1 GAP85996.1 - 0.12 11.7 0.1 0.12 11.7 0.1 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) DUF3040 PF11239.3 GAP85996.1 - 0.2 11.7 0.2 0.2 11.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) PAN_1 PF00024.21 GAP85997.1 - 2.6e-08 33.4 2.9 0.0037 16.9 0.6 2.3 2 0 0 2 2 2 2 PAN domain PAN_4 PF14295.1 GAP85997.1 - 1.8e-06 27.5 3.8 0.00051 19.7 0.1 2.4 2 0 0 2 2 2 2 PAN domain PAN_3 PF08277.7 GAP85997.1 - 0.073 12.6 2.2 2.4 7.8 0.1 2.5 2 0 0 2 2 2 0 PAN-like domain R3H-assoc PF13902.1 GAP85998.1 - 3.7e-08 33.3 0.4 8e-08 32.3 0.3 1.5 1 0 0 1 1 1 1 R3H-associated N-terminal domain Fungal_trans PF04082.13 GAP85999.1 - 5.1e-15 55.0 0.1 7.9e-14 51.1 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP85999.1 - 1.3e-08 34.5 8.2 2.5e-08 33.6 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2580 PF10824.3 GAP85999.1 - 0.11 12.8 0.5 22 5.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2580) Epimerase PF01370.16 GAP86000.1 - 1.4e-11 44.3 0.2 2.7e-10 40.1 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAP86000.1 - 6.5e-11 41.4 0.3 7.2e-09 34.7 0.1 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 GAP86000.1 - 3.6e-09 35.9 0.2 6.1e-05 22.0 0.0 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain NAD_binding_10 PF13460.1 GAP86000.1 - 3.6e-08 33.6 0.3 1.2e-07 31.9 0.1 1.8 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 GAP86000.1 - 3.6e-08 32.9 0.3 5.6e-08 32.3 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 GAP86000.1 - 1.3e-06 27.6 0.2 2.2e-06 26.9 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 GAP86000.1 - 4e-06 26.8 0.3 8.7e-06 25.7 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 GAP86000.1 - 6.2e-05 22.0 0.2 0.0048 15.8 0.0 2.4 2 1 1 3 3 3 1 Male sterility protein TrkA_N PF02254.13 GAP86000.1 - 0.00082 19.3 0.2 0.0018 18.2 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.5 GAP86000.1 - 0.00099 18.8 0.2 0.0018 18.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 GAP86000.1 - 0.0017 17.2 0.1 0.0034 16.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 GAP86000.1 - 0.019 15.2 0.1 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain HTH_13 PF11972.3 GAP86000.1 - 0.026 14.3 0.0 0.072 12.9 0.0 1.7 1 0 0 1 1 1 0 HTH DNA binding domain Propep_M14 PF02244.11 GAP86000.1 - 0.049 13.3 0.1 0.099 12.3 0.1 1.4 1 0 0 1 1 1 0 Carboxypeptidase activation peptide B12-binding PF02310.14 GAP86000.1 - 0.06 13.2 0.1 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 B12 binding domain Chitin_synth_1 PF01644.12 GAP86001.1 - 5.1e-83 276.7 0.1 7.7e-83 276.1 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 GAP86001.1 - 9.8e-33 111.6 0.2 2e-32 110.6 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 GAP86001.1 - 8.9e-23 80.4 6.0 3.7e-22 78.4 0.0 2.4 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 GAP86001.1 - 4.8e-08 32.9 3.8 6.9e-07 29.1 3.4 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAP86001.1 - 0.00012 22.0 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Polysacc_deac_1 PF01522.16 GAP86002.1 - 3.3e-25 88.1 0.0 5.6e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF4234 PF14018.1 GAP86002.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) Sigma_reg_N PF13800.1 GAP86002.1 - 0.17 11.9 0.2 0.33 11.0 0.1 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal WD40 PF00400.27 GAP86004.1 - 3e-24 83.9 9.7 1.4e-06 27.9 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 GAP86004.1 - 4.9e-05 21.6 2.5 0.00033 18.9 0.1 2.9 3 1 0 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAP86004.1 - 0.00018 20.3 0.1 0.31 9.7 0.0 3.1 2 1 0 3 3 3 2 Nup133 N terminal like Cyclin_N PF00134.18 GAP86004.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain OB_NTP_bind PF07717.11 GAP86005.1 - 9.6e-26 89.8 0.3 1.9e-23 82.4 0.0 3.6 4 0 0 4 4 4 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 GAP86005.1 - 1.1e-25 89.6 0.4 3.9e-25 87.8 0.0 2.3 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 GAP86005.1 - 3.2e-12 46.1 0.0 1.1e-11 44.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAP86005.1 - 2.5e-08 33.5 0.0 5.2e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAP86005.1 - 0.00012 22.2 0.0 0.00031 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 GAP86005.1 - 0.0006 18.8 0.0 0.0011 17.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.9 GAP86005.1 - 0.0014 18.3 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain T2SE PF00437.15 GAP86005.1 - 0.0016 17.3 0.1 0.0047 15.8 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein SRP54 PF00448.17 GAP86005.1 - 0.0023 17.4 0.0 0.005 16.3 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 GAP86005.1 - 0.003 17.4 4.2 0.31 10.8 0.0 3.3 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit KaiC PF06745.8 GAP86005.1 - 0.0047 16.0 0.0 0.0094 15.0 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_14 PF13173.1 GAP86005.1 - 0.0075 16.1 0.4 0.071 13.0 0.3 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 GAP86005.1 - 0.01 15.4 0.0 0.01 15.4 0.0 2.1 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.1 GAP86005.1 - 0.013 15.8 0.3 0.34 11.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 GAP86005.1 - 0.018 14.4 0.3 5 6.4 0.0 2.3 1 1 0 2 2 2 0 AAA-like domain NACHT PF05729.7 GAP86005.1 - 0.052 13.2 0.2 0.4 10.3 0.1 2.2 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 GAP86005.1 - 0.073 12.7 0.0 0.073 12.7 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase ABC_tran PF00005.22 GAP86005.1 - 0.085 13.1 0.7 0.27 11.5 0.0 2.2 3 0 0 3 3 1 0 ABC transporter Acylphosphatase PF00708.13 GAP86006.1 - 3.4e-24 84.7 0.0 3.7e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase TrpBP PF02081.10 GAP86006.1 - 0.11 11.9 0.2 1.3 8.5 0.0 2.2 1 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein DUF3539 PF12058.3 GAP86006.1 - 0.11 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3539) Hep_59 PF07052.6 GAP86007.1 - 2e-12 47.3 0.3 2e-12 47.3 0.2 3.0 2 2 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 Pyrid_oxidase_2 PF13883.1 GAP86007.1 - 0.063 13.0 0.6 0.31 10.7 0.1 2.1 2 1 1 3 3 3 0 Pyridoxamine 5'-phosphate oxidase NinF PF05810.7 GAP86008.1 - 0.061 13.1 5.4 0.14 11.9 3.7 1.6 1 0 0 1 1 1 0 NinF protein DUF4449 PF14613.1 GAP86008.1 - 0.17 11.7 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) zf-UDP PF14569.1 GAP86008.1 - 0.32 10.7 7.0 0.7 9.6 4.9 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger C1_3 PF07649.7 GAP86008.1 - 0.55 10.3 9.4 1.1 9.2 6.5 1.6 1 0 0 1 1 1 0 C1-like domain zf-RING_2 PF13639.1 GAP86008.1 - 1.6 8.5 11.7 3.2 7.6 8.1 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 GAP86008.1 - 4.1 7.2 13.4 18 5.1 2.9 2.6 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAP86008.1 - 5.2 7.1 12.9 16 5.5 8.9 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sulfotransfer_3 PF13469.1 GAP86009.1 - 7e-06 27.0 0.5 3.2e-05 24.9 0.3 2.2 1 1 0 1 1 1 1 Sulfotransferase family Lactamase_B_3 PF13483.1 GAP86010.1 - 1.1e-07 31.6 0.0 2.6e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain EF-hand_1 PF00036.27 GAP86011.1 - 4.4e-27 91.2 7.1 7.6e-07 28.0 0.1 5.3 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.1 GAP86011.1 - 5e-25 87.4 5.0 6.3e-10 39.0 0.0 3.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 GAP86011.1 - 1.9e-22 77.0 7.7 0.00024 20.7 0.1 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 GAP86011.1 - 3.1e-20 71.5 11.5 3.9e-10 39.1 0.1 4.7 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.1 GAP86011.1 - 5e-18 63.5 7.1 4.6e-05 22.5 0.2 4.4 4 0 0 4 4 4 4 EF hand GUN4 PF05419.7 GAP86011.1 - 0.093 12.5 0.0 0.19 11.5 0.0 1.5 2 0 0 2 2 2 0 GUN4-like EF-hand_4 PF12763.2 GAP86011.1 - 0.23 11.1 2.2 2 8.1 0.0 2.7 1 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Ank_2 PF12796.2 GAP86012.1 - 3.7e-117 382.9 7.2 1.7e-20 73.1 1.5 11.0 2 2 8 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.25 GAP86012.1 - 8.4e-108 347.2 49.1 3.4e-08 32.8 0.0 22.4 22 0 0 22 22 22 19 Ankyrin repeat Ank_3 PF13606.1 GAP86012.1 - 1.6e-73 235.2 25.8 1.8e-07 30.7 0.0 19.8 20 0 0 20 20 20 13 Ankyrin repeat Ank_4 PF13637.1 GAP86012.1 - 1.7e-72 238.5 30.4 3.3e-10 40.2 0.5 15.6 10 4 5 15 15 15 12 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP86012.1 - 2.4e-68 224.6 30.3 2e-11 43.7 0.0 14.5 10 3 6 16 16 16 12 Ankyrin repeats (many copies) NACHT PF05729.7 GAP86012.1 - 0.0013 18.4 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain HeLo PF14479.1 GAP86014.1 - 8.1e-34 117.2 0.0 1.3e-33 116.5 0.0 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation ChaC PF04752.7 GAP86014.1 - 4e-24 85.5 0.9 1.8e-12 47.6 1.2 2.5 1 1 1 2 2 2 2 ChaC-like protein RRM_1 PF00076.17 GAP86015.1 - 5.8e-23 80.3 0.0 8e-23 79.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP86015.1 - 2.1e-15 56.4 0.0 3e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP86015.1 - 2.4e-09 36.9 0.0 3.3e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HpcH_HpaI PF03328.9 GAP86017.1 - 8.3e-37 126.2 0.0 1.7e-36 125.1 0.0 1.5 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 GAP86017.1 - 1.2e-10 40.8 0.0 1.3e-06 27.4 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold SR-25 PF10500.4 GAP86017.1 - 7.3 5.9 7.6 11 5.3 5.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.20 GAP86018.1 - 4.7e-59 199.6 0.0 6.3e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP86018.1 - 3e-31 108.4 0.0 3.8e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP86018.1 - 0.00011 21.3 0.0 0.0009 18.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 GAP86018.1 - 0.0015 17.4 0.3 0.0027 16.5 0.0 1.5 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase Kdo PF06293.9 GAP86018.1 - 0.0025 16.9 0.0 0.0038 16.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 GAP86018.1 - 0.018 14.6 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 GAP86018.1 - 0.051 13.2 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 GAP86018.1 - 0.2 11.0 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase PF00069.20 GAP86020.1 - 1.1e-52 178.7 0.0 1.5e-52 178.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP86020.1 - 1.8e-24 86.2 0.0 6.2e-24 84.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP86020.1 - 0.015 14.2 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 GAP86020.1 - 0.036 13.4 0.0 0.08 12.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 GAP86020.1 - 0.05 12.4 0.0 0.078 11.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TMA7 PF09072.5 GAP86021.1 - 1.1e-28 99.5 16.5 1.2e-28 99.3 11.4 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 HlyIII PF03006.15 GAP86022.1 - 4.5e-60 202.8 10.2 5.3e-60 202.5 7.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related WD40 PF00400.27 GAP86023.1 - 4.8e-09 35.7 2.1 0.017 14.9 0.2 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Ank PF00023.25 GAP86024.1 - 5.6e-32 107.9 2.8 4.9e-08 32.3 0.0 7.0 6 1 1 7 7 7 6 Ankyrin repeat Ank_2 PF12796.2 GAP86024.1 - 7.1e-32 109.5 0.0 4.9e-12 46.0 0.0 4.0 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAP86024.1 - 1.8e-23 80.2 0.5 3.4e-05 23.6 0.0 6.8 6 1 1 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 GAP86024.1 - 2.5e-21 75.6 0.5 1.7e-08 34.7 0.0 5.8 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP86024.1 - 1.2e-20 73.0 1.3 8.5e-08 32.2 0.1 4.9 3 1 2 5 5 5 3 Ankyrin repeats (many copies) SpoU_sub_bind PF08032.7 GAP86024.1 - 0.11 12.7 0.0 1.4 9.1 0.0 2.4 2 1 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding HTH_33 PF13592.1 GAP86024.1 - 0.13 11.7 0.1 0.34 10.4 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix TPP_enzyme_N PF02776.13 GAP86025.1 - 7.9e-56 188.2 0.1 6.1e-55 185.3 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 GAP86025.1 - 5.7e-50 168.8 0.0 2e-48 163.8 0.0 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 GAP86025.1 - 1.9e-38 131.3 0.5 9.9e-38 128.9 0.1 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.11 GAP86025.1 - 0.13 11.7 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit GalKase_gal_bdg PF10509.4 GAP86026.1 - 1.6e-19 68.9 0.0 2.8e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 GAP86026.1 - 1.6e-13 50.6 0.0 4.1e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 GAP86026.1 - 2.9e-13 49.6 2.6 1.1e-12 47.8 1.8 2.1 1 0 0 1 1 1 1 GHMP kinases N terminal domain Sigma70_r3 PF04539.11 GAP86026.1 - 0.054 13.3 0.1 0.31 10.9 0.0 2.2 1 1 1 2 2 2 0 Sigma-70 region 3 HTH_3 PF01381.17 GAP86026.1 - 0.13 12.1 0.0 31 4.5 0.0 3.6 3 1 1 4 4 4 0 Helix-turn-helix Potass_KdpF PF09604.5 GAP86027.1 - 0.21 11.4 2.0 0.37 10.6 1.4 1.4 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) DPBB_1 PF03330.13 GAP86028.1 - 4.3e-07 29.8 0.1 3.2e-06 27.0 0.0 2.3 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 GAP86028.1 - 9.7e-05 22.0 0.0 0.00022 20.8 0.0 1.6 1 0 0 1 1 1 1 Barwin family Cerato-platanin PF07249.7 GAP86028.1 - 0.00016 21.6 0.4 0.0004 20.3 0.2 1.7 1 1 0 1 1 1 1 Cerato-platanin Pollen_allerg_1 PF01357.16 GAP86028.1 - 0.0086 15.8 0.5 0.018 14.8 0.4 1.5 1 0 0 1 1 1 1 Pollen allergen BNR PF02012.15 GAP86028.1 - 0.039 13.7 0.9 0.12 12.2 0.6 1.9 1 0 0 1 1 1 0 BNR/Asp-box repeat Mo-co_dimer PF03404.11 GAP86028.1 - 0.05 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain K_channel_TID PF07941.6 GAP86029.1 - 8.8 6.6 6.5 1.2 9.4 1.2 2.0 1 1 1 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Annexin PF00191.15 GAP86030.1 - 5.3e-73 240.8 4.3 6.7e-21 73.9 0.0 4.2 4 0 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.1 GAP86030.1 - 0.0059 16.8 3.3 23 5.3 0.0 4.0 4 0 0 4 4 4 2 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Fumerase PF05681.9 GAP86030.1 - 0.17 10.9 0.1 1.7 7.6 0.0 2.1 2 0 0 2 2 2 0 Fumarate hydratase (Fumerase) ABC_tran PF00005.22 GAP86031.1 - 1.1e-44 152.0 0.0 3.3e-28 98.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAP86031.1 - 1.5e-26 93.4 22.8 8.5e-15 54.8 8.1 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 GAP86031.1 - 7.8e-10 38.3 0.9 0.00073 18.8 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAP86031.1 - 2.7e-07 30.8 0.0 0.33 10.8 0.0 4.4 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.1 GAP86031.1 - 5.9e-06 26.4 0.1 0.12 12.5 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAP86031.1 - 9e-06 25.7 2.9 0.011 15.6 0.3 3.0 2 1 0 2 2 2 2 AAA ATPase domain NACHT PF05729.7 GAP86031.1 - 2.4e-05 24.0 0.1 0.029 14.0 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_25 PF13481.1 GAP86031.1 - 2.5e-05 23.7 0.0 0.011 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 GAP86031.1 - 5.9e-05 22.5 0.9 0.0035 16.8 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 GAP86031.1 - 0.00047 19.3 0.0 0.35 10.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 GAP86031.1 - 0.00058 19.3 0.1 0.062 12.7 0.0 2.6 2 0 0 2 2 2 1 AAA-like domain DUF87 PF01935.12 GAP86031.1 - 0.0015 18.3 1.7 0.011 15.5 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 cobW PF02492.14 GAP86031.1 - 0.0017 17.8 0.2 0.071 12.5 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 GAP86031.1 - 0.0019 17.1 1.7 0.59 8.9 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.1 GAP86031.1 - 0.0023 18.3 4.1 0.22 11.8 0.1 2.9 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 GAP86031.1 - 0.0023 18.3 0.1 0.83 10.1 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 GAP86031.1 - 0.0076 15.7 0.5 0.35 10.3 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family Zeta_toxin PF06414.7 GAP86031.1 - 0.0084 15.2 2.5 0.76 8.8 0.0 2.7 3 0 0 3 3 3 1 Zeta toxin MMR_HSR1 PF01926.18 GAP86031.1 - 0.013 15.4 0.1 0.64 9.9 0.0 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase DUF2075 PF09848.4 GAP86031.1 - 0.029 13.3 0.8 5.3 5.9 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 GAP86031.1 - 0.041 13.7 0.1 9.2 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 GAP86031.1 - 0.047 13.4 0.2 12 5.6 0.0 2.6 2 0 0 2 2 2 0 Dynamin family MobB PF03205.9 GAP86031.1 - 0.078 12.6 0.2 13 5.4 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 GAP86031.1 - 0.12 12.5 0.1 24 5.1 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 GAP86031.1 - 0.14 11.8 0.2 5.7 6.5 0.0 2.9 3 0 0 3 3 3 0 Archaeal ATPase AAA_17 PF13207.1 GAP86031.1 - 0.17 12.7 0.5 2.8 8.7 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.1 GAP86031.1 - 0.18 12.1 0.0 7.5 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 GAP86031.1 - 0.2 11.2 2.6 14 5.1 0.8 2.9 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 GAP86031.1 - 0.25 11.1 2.3 20 5.0 0.3 2.9 2 0 0 2 2 2 0 Part of AAA domain GTP_EFTU PF00009.22 GAP86031.1 - 0.29 10.5 0.6 20 4.5 0.0 2.8 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain Pox_A32 PF04665.7 GAP86031.1 - 0.36 10.1 0.3 26 4.0 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein Baculo_ME53 PF06061.6 GAP86032.1 - 0.08 11.9 1.3 0.16 10.9 0.9 1.4 1 0 0 1 1 1 0 Baculoviridae ME53 HLH PF00010.21 GAP86033.1 - 0.11 12.1 0.2 0.11 12.1 0.1 3.2 3 1 0 3 3 3 0 Helix-loop-helix DNA-binding domain Viral_P18 PF04521.8 GAP86033.1 - 0.9 8.9 2.3 1.8 7.9 0.1 2.1 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein HR1 PF02185.11 GAP86033.1 - 1.2 8.9 9.8 0.17 11.6 0.5 3.2 3 1 1 4 4 4 0 Hr1 repeat PCI PF01399.22 GAP86034.1 - 3.6e-15 56.1 0.8 1.3e-14 54.3 0.3 2.2 2 0 0 2 2 2 1 PCI domain DUF1451 PF07295.6 GAP86034.1 - 0.023 14.4 5.1 1.8 8.3 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1451) ADK PF00406.17 GAP86035.1 - 4.1e-42 143.5 0.1 2.6e-23 82.5 0.0 2.1 1 1 1 2 2 2 2 Adenylate kinase AAA_17 PF13207.1 GAP86035.1 - 4.2e-08 34.0 0.1 1.5e-07 32.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAP86035.1 - 9.8e-07 28.7 0.5 2.2e-06 27.5 0.3 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAP86035.1 - 3.1e-06 27.5 0.1 9.5e-06 25.9 0.0 1.8 2 1 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 GAP86035.1 - 0.00056 19.3 0.1 0.0019 17.6 0.1 1.7 1 1 0 1 1 1 1 Thymidylate kinase AAA_19 PF13245.1 GAP86035.1 - 0.008 15.9 0.1 0.019 14.7 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Dicty_REP PF05086.7 GAP86035.1 - 0.083 10.6 0.4 0.092 10.4 0.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF202 PF02656.10 GAP86036.1 - 0.04 14.1 4.8 0.48 10.6 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) MARVEL PF01284.18 GAP86036.1 - 0.94 9.2 11.3 1.5 8.5 6.7 2.1 1 1 1 2 2 2 0 Membrane-associating domain Nsp1_C PF05064.8 GAP86038.1 - 9.8e-39 131.6 3.0 2.1e-38 130.5 2.1 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 GAP86038.1 - 6.3e-12 45.7 202.8 1.6e-05 25.1 30.4 7.4 1 1 4 5 5 5 3 Nucleoporin FG repeat region Myosin_tail_1 PF01576.14 GAP86038.1 - 0.0017 16.2 3.2 0.0026 15.5 2.2 1.2 1 0 0 1 1 1 1 Myosin tail RepB PF07506.6 GAP86038.1 - 0.11 12.3 0.1 0.28 11.0 0.1 1.6 1 0 0 1 1 1 0 RepB plasmid partitioning protein V-SNARE PF05008.10 GAP86038.1 - 0.29 11.3 7.0 0.88 9.7 0.3 3.2 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus 14-3-3 PF00244.15 GAP86039.1 - 3e-116 386.5 3.6 3.4e-116 386.3 2.5 1.0 1 0 0 1 1 1 1 14-3-3 protein Peptidase_M17_N PF02789.12 GAP86039.1 - 0.017 14.8 0.2 0.069 12.9 0.0 2.0 2 1 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain zf-CSL PF05207.8 GAP86040.1 - 1.4e-17 62.9 0.3 2.1e-17 62.3 0.2 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 GAP86040.1 - 1.6e-12 46.9 3.4 3.6e-12 45.8 2.4 1.6 1 1 0 1 1 1 1 DnaJ domain DEAD PF00270.24 GAP86042.1 - 1.2e-41 141.9 0.0 8.1e-41 139.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP86042.1 - 8e-25 86.5 0.2 1.9e-24 85.3 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3334 PF11813.3 GAP86042.1 - 0.072 12.6 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) PRAI PF00697.17 GAP86042.1 - 0.12 11.8 1.6 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_M1 PF01433.15 GAP86043.1 - 6.4e-139 463.3 0.1 8.4e-139 462.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 GAP86043.1 - 1.3e-90 303.9 0.0 2.4e-90 303.0 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 GAP86043.1 - 2.2e-19 69.7 0.2 4.4e-19 68.7 0.1 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily DUF1360 PF07098.6 GAP86043.1 - 0.15 11.8 0.2 0.37 10.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) Enolase_C PF00113.17 GAP86044.1 - 1.4e-152 506.8 0.2 1.8e-152 506.4 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 GAP86044.1 - 2.6e-57 192.4 0.4 5.2e-57 191.4 0.2 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 GAP86044.1 - 0.0018 17.2 0.8 0.11 11.4 0.1 2.9 3 0 0 3 3 3 1 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 GAP86044.1 - 0.048 14.2 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Ribosomal_S13_N PF08069.7 GAP86045.1 - 3.3e-28 97.2 1.2 4e-28 97.0 0.2 1.6 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 GAP86045.1 - 8.9e-22 76.6 0.1 2.1e-21 75.4 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S15 PAX PF00292.13 GAP86045.1 - 0.015 15.0 0.0 0.037 13.7 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain Dpy-30 PF05186.8 GAP86046.1 - 1.6e-15 56.2 0.1 3.9e-14 51.8 0.0 2.2 2 0 0 2 2 2 2 Dpy-30 motif VRR_NUC PF08774.6 GAP86047.1 - 1.4e-16 60.2 0.0 3.3e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain CBFB_NFYA PF02045.10 GAP86050.1 - 4.7e-30 103.9 4.3 1.4e-29 102.4 3.0 1.8 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B TFIIA PF03153.8 GAP86050.1 - 0.13 12.1 16.1 0.18 11.6 11.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LSM PF01423.17 GAP86051.1 - 6.1e-17 60.9 1.0 8e-17 60.5 0.7 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 GAP86051.1 - 0.012 15.5 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Glutaredoxin2_C PF04399.8 GAP86051.1 - 0.035 13.6 0.1 0.04 13.4 0.0 1.1 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Gemin7 PF11095.3 GAP86051.1 - 0.041 13.6 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) DRMBL PF07522.9 GAP86052.1 - 4.1e-30 104.0 0.0 8e-30 103.1 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 GAP86052.1 - 6.2e-11 42.2 0.0 1.6e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain zf-Di19 PF05605.7 GAP86052.1 - 0.011 15.8 0.5 0.051 13.7 0.0 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PDEase_II PF02112.10 GAP86052.1 - 0.45 9.3 0.0 26 3.6 0.0 2.1 2 0 0 2 2 2 0 cAMP phosphodiesterases class-II Sugar_tr PF00083.19 GAP86053.1 - 9.7e-21 73.8 22.2 9.3e-19 67.3 15.4 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter AP_endonuc_2 PF01261.19 GAP86054.1 - 8e-27 93.9 0.2 1.2e-26 93.3 0.1 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Mad3_BUB1_I PF08311.7 GAP86055.1 - 7.4e-42 142.1 0.5 1.2e-41 141.3 0.3 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 GAP86055.1 - 2.2e-09 36.8 0.0 5.2e-09 35.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Mad3_BUB1_II PF08171.6 GAP86055.1 - 0.0036 17.1 0.0 0.016 15.1 0.0 2.0 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 Pkinase_Tyr PF07714.12 GAP86055.1 - 0.013 14.5 0.0 0.28 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase Kinase-like PF14531.1 GAP86055.1 - 0.3 9.9 0.0 0.53 9.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like TENA_THI-4 PF03070.11 GAP86056.1 - 1.3e-08 34.8 0.0 2e-07 30.9 0.0 2.1 1 1 0 1 1 1 1 TENA/THI-4/PQQC family RRM_1 PF00076.17 GAP86057.1 - 1.3e-22 79.1 0.1 3e-10 39.5 0.0 3.7 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP86057.1 - 1.7e-13 50.3 0.0 0.002 18.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP86057.1 - 5.8e-12 45.2 0.3 6.1e-07 29.1 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OGG_N PF07934.7 GAP86058.1 - 1.8e-36 124.6 0.2 3.7e-36 123.6 0.1 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 GAP86058.1 - 3e-15 56.4 0.0 4.8e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 GAP86058.1 - 0.002 17.7 0.0 0.0039 16.7 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif zf-H2C2_2 PF13465.1 GAP86059.1 - 1.7e-10 40.6 16.4 2.5e-06 27.5 1.1 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 GAP86059.1 - 4.8e-09 36.0 15.0 1.8e-05 24.8 3.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP86059.1 - 6.1e-07 29.3 12.1 0.00018 21.5 1.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 GAP86059.1 - 5.5e-06 26.3 1.5 1.8e-05 24.7 1.0 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 GAP86059.1 - 6.2e-05 23.0 5.1 0.00011 22.2 1.4 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 GAP86059.1 - 0.00056 19.7 6.4 0.0036 17.1 1.1 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 GAP86059.1 - 0.038 14.1 1.0 0.038 14.1 0.7 1.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) CCAP PF11105.3 GAP86059.1 - 0.093 12.4 0.8 0.16 11.6 0.6 1.4 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a zf-BED PF02892.10 GAP86059.1 - 5.7 6.7 7.7 56 3.6 5.3 2.3 1 1 0 1 1 1 0 BED zinc finger SF3b1 PF08920.5 GAP86061.1 - 8.1e-24 84.3 0.8 1.1e-22 80.5 0.0 2.4 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 GAP86061.1 - 1e-14 54.5 1.9 0.011 16.0 0.0 7.7 6 3 3 9 9 9 5 HEAT repeats HEAT PF02985.17 GAP86061.1 - 3e-10 39.2 8.4 0.58 10.3 0.0 9.5 11 0 0 11 11 11 2 HEAT repeat HEAT_EZ PF13513.1 GAP86061.1 - 6.2e-10 39.2 1.5 0.21 12.1 0.0 7.5 7 1 1 8 8 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 GAP86061.1 - 0.0001 22.6 0.2 2.2 8.7 0.0 5.2 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region UPF0236 PF06782.6 GAP86061.1 - 0.00071 18.1 0.0 0.0012 17.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0236) CLASP_N PF12348.3 GAP86061.1 - 0.0033 16.7 0.1 0.92 8.8 0.0 3.4 3 0 0 3 3 3 1 CLASP N terminal Adaptin_N PF01602.15 GAP86061.1 - 0.0034 15.7 0.1 1.4 7.0 0.0 3.1 2 2 0 3 3 3 2 Adaptin N terminal region NUC173 PF08161.7 GAP86061.1 - 0.019 14.3 0.4 9.1 5.5 0.0 3.8 4 0 0 4 4 4 0 NUC173 domain Rax2 PF12768.2 GAP86062.1 - 1.7e-91 306.3 3.9 1.2e-81 273.9 0.0 4.8 5 0 0 5 5 5 4 Cortical protein marker for cell polarity SNase PF00565.12 GAP86063.1 - 1.7e-25 89.3 0.0 2.3e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue PKD_channel PF08016.7 GAP86064.1 - 0.0035 15.8 8.4 0.082 11.3 1.1 2.2 2 0 0 2 2 2 2 Polycystin cation channel M157 PF11624.3 GAP86064.1 - 0.11 11.5 0.3 0.19 10.8 0.2 1.2 1 0 0 1 1 1 0 MHC class I-like protein M157 Methyltransf_26 PF13659.1 GAP86065.1 - 5.7e-18 65.0 2.4 8.3e-18 64.5 1.7 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAP86065.1 - 9.3e-05 21.8 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain LSM PF01423.17 GAP86066.1 - 4.3e-16 58.2 0.0 5.9e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 GAP86066.1 - 0.0017 18.2 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain API5 PF05918.6 GAP86066.1 - 0.91 7.9 3.9 1.1 7.6 2.7 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Ribosomal_S8e PF01201.17 GAP86067.1 - 1e-31 109.8 4.2 2.4e-31 108.5 2.9 1.6 1 1 0 1 1 1 1 Ribosomal protein S8e YebF PF13995.1 GAP86067.1 - 0.11 12.5 0.4 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 YebF-like protein Pkr1 PF08636.5 GAP86068.1 - 5.7e-32 109.6 6.8 7.2e-32 109.2 4.7 1.1 1 0 0 1 1 1 1 ER protein Pkr1 DUF1049 PF06305.6 GAP86068.1 - 0.03 13.8 0.8 0.05 13.0 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) OAD_gamma PF04277.8 GAP86068.1 - 0.088 13.1 4.5 0.45 10.9 3.1 2.4 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain F-box PF00646.28 GAP86070.1 - 0.00097 18.7 0.7 0.0079 15.8 0.0 2.8 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 GAP86070.1 - 0.034 13.8 0.1 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 F-box-like F-box-like_2 PF13013.1 GAP86070.1 - 0.088 12.5 0.1 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 F-box-like domain DUF500 PF04366.7 GAP86071.1 - 1.9e-29 101.6 0.0 3e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) Actin PF00022.14 GAP86072.1 - 7.2e-17 60.8 0.0 4.2e-14 51.7 0.0 2.5 3 0 0 3 3 3 2 Actin ADH_zinc_N PF00107.21 GAP86073.1 - 1.3e-29 102.3 0.3 4.2e-29 100.7 0.2 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAP86073.1 - 5.7e-17 62.8 0.3 1.5e-16 61.4 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP86073.1 - 3.1e-08 33.3 0.0 7.6e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SnoaL_2 PF12680.2 GAP86073.1 - 0.034 14.5 0.6 1.9 8.9 0.0 2.9 1 1 2 3 3 3 0 SnoaL-like domain HupF_HypC PF01455.13 GAP86073.1 - 0.13 12.3 0.1 0.4 10.6 0.0 1.9 2 0 0 2 2 2 0 HupF/HypC family Cpn60_TCP1 PF00118.19 GAP86074.1 - 1.1e-136 456.3 15.0 1.4e-136 456.0 10.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 GAP86074.1 - 0.012 15.1 0.1 0.039 13.4 0.0 1.9 2 0 0 2 2 2 0 Phage Tail Protein X DUF3924 PF13062.1 GAP86074.1 - 0.036 13.9 0.0 0.8 9.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3924) AAA PF00004.24 GAP86076.1 - 2.4e-40 137.7 0.0 4.1e-40 137.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAP86076.1 - 3.8e-06 27.0 0.0 0.00061 19.9 0.0 2.9 3 1 0 3 3 2 1 AAA domain AAA_5 PF07728.9 GAP86076.1 - 2.5e-05 24.0 0.1 0.00028 20.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAP86076.1 - 0.00027 20.9 0.1 0.0016 18.4 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 GAP86076.1 - 0.00035 20.5 0.0 0.0013 18.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 GAP86076.1 - 0.0016 17.3 0.0 0.0029 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 GAP86076.1 - 0.0042 17.9 0.1 0.014 16.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAP86076.1 - 0.0087 15.7 0.1 0.021 14.5 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 GAP86076.1 - 0.0096 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 GAP86076.1 - 0.014 15.2 0.0 0.037 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 GAP86076.1 - 0.019 14.9 0.0 0.045 13.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 GAP86076.1 - 0.033 13.7 0.1 0.61 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 GAP86076.1 - 0.035 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 GAP86076.1 - 0.047 13.8 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 GAP86076.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 GAP86076.1 - 0.072 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 GAP86076.1 - 0.078 13.0 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 GAP86076.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 GAP86076.1 - 0.13 11.3 0.0 0.31 10.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 GAP86076.1 - 0.15 11.4 0.2 0.48 9.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain SSP160 PF06933.6 GAP86077.1 - 1.2 7.0 6.4 1.6 6.5 4.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RRM_1 PF00076.17 GAP86078.1 - 3e-11 42.7 0.1 5.8e-11 41.8 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP86078.1 - 4.2e-09 36.2 0.0 9.7e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP86078.1 - 0.0003 20.5 0.0 0.00066 19.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hemolysin_N PF12563.3 GAP86078.1 - 0.045 13.1 0.1 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Hemolytic toxin N terminal SR-25 PF10500.4 GAP86078.1 - 0.2 11.0 9.2 0.34 10.3 6.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3661 PF12400.3 GAP86079.1 - 3.2e-43 146.9 5.1 5.4e-43 146.1 3.5 1.4 1 0 0 1 1 1 1 Vaculolar membrane protein Corona_S2 PF01601.11 GAP86080.1 - 0.25 9.3 14.5 0.34 8.9 10.1 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein RCR PF12273.3 GAP86082.1 - 1.4e-20 74.2 8.1 2.1e-20 73.5 5.6 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF1183 PF06682.7 GAP86082.1 - 0.00077 19.1 0.2 0.00095 18.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) DUF3328 PF11807.3 GAP86082.1 - 0.085 12.5 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) FixQ PF05545.6 GAP86082.1 - 0.38 10.4 3.5 0.7 9.5 2.4 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Shisa PF13908.1 GAP86082.1 - 5.1 7.2 5.4 10 6.2 3.7 1.7 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator PROL5-SMR PF15621.1 GAP86082.1 - 5.3 7.5 8.7 11 6.5 6.0 1.6 1 1 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family Arf PF00025.16 GAP86083.1 - 1.5e-42 144.8 0.0 1.6e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 GAP86083.1 - 2.8e-18 65.8 0.0 3.2e-18 65.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAP86083.1 - 7e-10 39.4 0.0 1.4e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 GAP86083.1 - 1.4e-05 24.3 0.0 1.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 GAP86083.1 - 1.8e-05 23.6 0.2 5e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 G-protein alpha subunit Gtr1_RagA PF04670.7 GAP86083.1 - 2.9e-05 23.3 0.0 3.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAP86083.1 - 5e-05 22.8 0.0 0.00054 19.4 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAP86083.1 - 0.00011 22.1 0.0 0.00019 21.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAP86083.1 - 0.011 15.0 0.2 0.029 13.6 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.4 GAP86083.1 - 0.094 12.1 0.1 0.32 10.4 0.0 1.9 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_pol_Rpb2_6 PF00562.23 GAP86084.1 - 3.1e-116 388.3 0.1 4e-116 387.9 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 GAP86084.1 - 2.2e-28 98.5 0.0 3.4e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 GAP86084.1 - 2.9e-25 87.8 0.0 7.1e-25 86.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 GAP86084.1 - 2.6e-23 82.4 0.0 4.4e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.7 GAP86084.1 - 1.3e-22 79.4 0.0 3.1e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 GAP86084.1 - 1.5e-14 54.0 0.0 7.2e-14 51.8 0.0 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 GAP86084.1 - 0.0058 16.5 0.1 0.014 15.3 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Tyrosinase PF00264.15 GAP86085.1 - 2.8e-54 184.6 2.4 4.7e-54 183.9 1.6 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Glyco_hydro_61 PF03443.9 GAP86086.1 - 2.1e-30 106.1 0.0 2.9e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ammonium_transp PF00909.16 GAP86088.1 - 1.1e-116 389.6 29.4 1.2e-116 389.4 20.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DNA_pol_B_palm PF14792.1 GAP86089.1 - 1.4e-35 121.6 0.0 3e-35 120.6 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.4 GAP86089.1 - 1.3e-21 75.8 0.0 2.7e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 GAP86089.1 - 2.1e-18 66.2 0.5 2.2e-17 62.9 0.3 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_B_thumb PF14791.1 GAP86089.1 - 1.6e-05 24.5 0.0 3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb Cdd1 PF11731.3 GAP86089.1 - 0.00038 20.3 0.0 0.1 12.5 0.0 2.4 1 1 1 2 2 2 2 Pathogenicity locus NTP_transf_2 PF01909.18 GAP86089.1 - 0.011 16.0 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain HHH_5 PF14520.1 GAP86089.1 - 0.029 14.5 0.3 0.32 11.1 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain PBP1_TM PF14812.1 GAP86089.1 - 0.14 12.5 1.0 0.47 10.8 0.7 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GMP_synt_C PF00958.17 GAP86090.1 - 2.8e-33 113.5 0.0 7.8e-33 112.0 0.0 1.7 2 0 0 2 2 2 1 GMP synthase C terminal domain GATase PF00117.23 GAP86090.1 - 2.9e-33 114.9 0.0 5.4e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 GAP86090.1 - 1.8e-08 33.6 0.0 7.8e-06 24.9 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 GAP86090.1 - 0.00011 21.7 0.0 0.00031 20.2 0.0 1.8 1 0 0 1 1 1 1 Peptidase C26 Asn_synthase PF00733.16 GAP86090.1 - 0.00033 20.2 0.4 0.0015 18.1 0.0 2.0 2 0 0 2 2 2 1 Asparagine synthase tRNA_Me_trans PF03054.11 GAP86090.1 - 0.003 16.1 0.1 0.0065 15.0 0.0 1.5 2 0 0 2 2 2 1 tRNA methyl transferase PAPS_reduct PF01507.14 GAP86090.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family QueC PF06508.8 GAP86090.1 - 0.014 14.6 0.0 0.09 12.0 0.0 2.1 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC ThiI PF02568.9 GAP86090.1 - 0.036 13.5 0.0 0.075 12.4 0.0 1.5 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.14 GAP86090.1 - 0.047 12.7 0.0 0.13 11.2 0.0 1.6 2 0 0 2 2 2 0 Arginosuccinate synthase ATP_bind_3 PF01171.15 GAP86090.1 - 0.14 11.6 0.0 0.42 10.0 0.0 1.7 2 0 0 2 2 2 0 PP-loop family PhoD PF09423.5 GAP86091.1 - 1.1e-148 495.6 2.6 1.3e-148 495.3 1.8 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase Methyltransf_31 PF13847.1 GAP86092.1 - 4e-11 42.7 0.1 7.5e-11 41.8 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 GAP86092.1 - 7.1e-11 41.6 0.1 1.2e-10 40.9 0.0 1.4 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PrmA PF06325.8 GAP86092.1 - 8.5e-11 41.5 0.4 1.5e-10 40.7 0.1 1.5 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 GAP86092.1 - 2.5e-07 30.7 0.0 1.4e-06 28.3 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 GAP86092.1 - 3.5e-07 29.2 0.2 5.3e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.2 GAP86092.1 - 5.9e-07 30.0 0.0 1.8e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP86092.1 - 1.1e-06 28.9 0.0 3.4e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP86092.1 - 6.1e-06 26.5 0.1 3.1e-05 24.2 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP86092.1 - 0.00015 21.5 0.0 0.00031 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAP86092.1 - 0.00042 19.7 1.0 0.0017 17.7 0.1 2.0 1 1 1 2 2 2 1 Methyltransferase small domain CMAS PF02353.15 GAP86092.1 - 0.0015 17.6 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 GAP86092.1 - 0.0039 17.6 0.0 0.0087 16.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 GAP86092.1 - 0.028 14.0 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Lum_binding PF00677.12 GAP86093.1 - 2.4e-34 117.0 0.0 8.9e-17 60.7 0.0 2.2 2 0 0 2 2 2 2 Lumazine binding domain ERCC4 PF02732.10 GAP86094.1 - 2.1e-30 105.3 0.1 3.3e-30 104.7 0.1 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 GAP86094.1 - 4.7e-06 26.6 0.0 1.2e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HTH_27 PF13463.1 GAP86094.1 - 0.055 13.7 0.0 0.23 11.8 0.0 2.1 1 0 0 1 1 1 0 Winged helix DNA-binding domain PGM_PMM_I PF02878.11 GAP86095.1 - 6.9e-16 57.9 0.1 1.3e-06 27.9 0.0 2.9 1 1 2 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 GAP86095.1 - 3.5e-14 53.0 0.0 1.8e-13 50.6 0.0 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 GAP86095.1 - 1.9e-09 37.3 0.4 6.8e-09 35.6 0.2 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 GAP86095.1 - 0.00058 19.8 0.0 0.0022 17.9 0.0 2.1 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DUF2392 PF10288.4 GAP86095.1 - 0.14 12.4 0.0 0.6 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2392) zf-trcl PF13451.1 GAP86096.1 - 0.014 15.0 0.2 0.039 13.5 0.1 1.7 1 0 0 1 1 1 0 Probable zinc-binding domain DZR PF12773.2 GAP86096.1 - 0.025 14.4 0.6 0.025 14.4 0.4 1.8 2 0 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.7 GAP86096.1 - 0.04 13.7 0.5 0.071 12.9 0.4 1.4 1 0 0 1 1 1 0 zinc-ribbons TF_Zn_Ribbon PF08271.7 GAP86096.1 - 0.071 12.4 0.7 0.16 11.2 0.5 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.2 GAP86096.1 - 1.6 8.5 5.3 0.91 9.3 0.5 2.0 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-H2C2_2 PF13465.1 GAP86096.1 - 4.3 7.8 6.2 2.7 8.4 0.8 2.7 2 0 0 2 2 2 0 Zinc-finger double domain Ribonuc_L-PSP PF01042.16 GAP86098.1 - 8.9e-42 141.6 0.0 9.8e-42 141.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP L27 PF02828.11 GAP86099.1 - 0.052 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 L27 domain PAT1 PF09770.4 GAP86100.1 - 0.45 8.6 23.6 0.62 8.2 16.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1845 PF08900.6 GAP86101.1 - 0.087 12.1 0.1 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) zf-C2H2_4 PF13894.1 GAP86101.1 - 0.12 12.8 18.7 0.45 10.9 1.8 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 GAP86101.1 - 2.5 8.5 12.9 0.39 11.0 2.4 3.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 GAP86101.1 - 4.9 7.6 14.7 0.23 11.8 2.7 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type Per1 PF04080.8 GAP86102.1 - 6e-106 353.7 6.4 7.4e-106 353.4 4.4 1.1 1 0 0 1 1 1 1 Per1-like DUF3433 PF11915.3 GAP86103.1 - 8e-25 86.8 11.5 2.8e-13 49.8 0.4 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) SNF2_N PF00176.18 GAP86104.1 - 1.9e-65 220.5 0.0 3e-65 219.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 GAP86104.1 - 1.5e-10 40.8 0.0 3.7e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 GAP86104.1 - 9.9e-06 25.5 0.0 2.5e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 GAP86104.1 - 0.00034 20.3 0.0 0.00089 19.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 GAP86104.1 - 0.014 15.0 7.5 0.029 14.1 5.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 GAP86104.1 - 0.024 14.4 3.8 0.054 13.3 2.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 GAP86104.1 - 0.042 13.5 7.5 0.12 12.0 5.2 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAP86104.1 - 0.18 11.6 7.5 0.4 10.5 5.2 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 GAP86104.1 - 0.23 11.5 8.6 0.62 10.1 6.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NACHT PF05729.7 GAP86105.1 - 5.3e-07 29.4 0.0 1.7e-06 27.7 0.0 1.9 2 0 0 2 2 1 1 NACHT domain AAA_16 PF13191.1 GAP86105.1 - 8.1e-07 29.1 0.0 4.1e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain zf-C2H2_4 PF13894.1 GAP86105.1 - 3.3e-06 27.0 22.0 0.013 15.7 0.4 5.3 5 0 0 5 5 5 3 C2H2-type zinc finger AAA_22 PF13401.1 GAP86105.1 - 5e-05 23.4 0.1 0.00019 21.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain zf-H2C2_2 PF13465.1 GAP86105.1 - 0.00082 19.5 0.8 0.00082 19.5 0.6 4.4 3 1 0 3 3 3 1 Zinc-finger double domain NB-ARC PF00931.17 GAP86105.1 - 0.0047 15.8 0.1 0.015 14.1 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain DUF2075 PF09848.4 GAP86105.1 - 0.014 14.4 0.2 0.043 12.7 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 GAP86105.1 - 0.025 14.4 0.0 0.075 12.8 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_17 PF13207.1 GAP86105.1 - 0.034 14.9 1.9 0.28 11.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain CLAMP PF14769.1 GAP86105.1 - 0.044 13.9 0.1 0.42 10.7 0.0 2.6 3 0 0 3 3 2 0 Flagellar C1a complex subunit C1a-32 AAA_19 PF13245.1 GAP86105.1 - 0.05 13.3 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain NTPase_1 PF03266.10 GAP86105.1 - 0.067 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 NTPase T2SE PF00437.15 GAP86105.1 - 0.069 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Histone_HNS PF00816.16 GAP86105.1 - 0.087 13.3 0.1 3.4 8.2 0.1 3.0 3 0 0 3 3 3 0 H-NS histone family DZR PF12773.2 GAP86105.1 - 0.1 12.4 1.8 0.25 11.1 1.2 1.7 1 0 0 1 1 1 0 Double zinc ribbon zf-C2H2 PF00096.21 GAP86105.1 - 0.12 12.7 0.1 0.12 12.7 0.1 4.9 5 0 0 5 5 4 0 Zinc finger, C2H2 type zf-C3HC4_3 PF13920.1 GAP86105.1 - 0.13 11.9 1.6 0.32 10.6 1.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sigma54_activat PF00158.21 GAP86105.1 - 0.15 11.5 0.0 0.35 10.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain HET PF06985.6 GAP86106.1 - 4.8e-22 78.6 0.0 1.1e-21 77.4 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Thioredoxin_7 PF13899.1 GAP86107.1 - 2.2e-14 53.2 0.0 6.1e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 GAP86107.1 - 2.3e-07 30.7 0.0 6.7e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 UBX domain UBA_4 PF14555.1 GAP86107.1 - 1.4e-05 24.4 0.0 4.7e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 UBA-like domain UIM PF02809.15 GAP86107.1 - 0.023 14.2 2.0 0.13 11.9 1.4 2.4 1 0 0 1 1 1 0 Ubiquitin interaction motif Thioredox_DsbH PF03190.10 GAP86107.1 - 0.036 13.7 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Fungal_trans PF04082.13 GAP86108.1 - 2.8e-14 52.6 0.0 5.6e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP86108.1 - 2.9e-09 36.6 10.5 2.9e-09 36.6 7.2 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HIT PF01230.18 GAP86109.1 - 1.1e-20 73.9 0.0 1.6e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 GAP86109.1 - 0.0024 18.0 0.1 0.038 14.2 0.1 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding AAA PF00004.24 GAP86110.1 - 1.4e-11 44.7 0.0 2.5e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAP86110.1 - 4.5e-07 30.0 0.0 1.1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 GAP86110.1 - 3.7e-05 23.4 0.0 7.8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 GAP86110.1 - 5.6e-05 22.2 0.0 0.0001 21.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 GAP86110.1 - 0.00013 21.5 0.0 0.00038 20.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 GAP86110.1 - 0.0004 20.2 0.5 0.0011 18.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 GAP86110.1 - 0.00063 18.5 0.0 0.001 17.8 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 GAP86110.1 - 0.00071 19.4 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAP86110.1 - 0.0015 19.3 0.0 0.012 16.3 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.1 GAP86110.1 - 0.0067 16.0 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAP86110.1 - 0.011 15.7 0.0 0.046 13.6 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 GAP86110.1 - 0.014 14.5 0.0 0.031 13.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.10 GAP86110.1 - 0.017 14.8 0.7 0.07 12.8 0.1 2.4 2 1 0 2 2 2 0 NTPase DUF258 PF03193.11 GAP86110.1 - 0.024 13.8 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 GAP86110.1 - 0.027 13.3 0.0 0.048 12.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 GAP86110.1 - 0.029 14.6 0.0 0.068 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 GAP86110.1 - 0.046 14.0 0.1 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.12 GAP86110.1 - 0.054 12.9 0.1 0.16 11.3 0.1 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.9 GAP86110.1 - 0.072 13.0 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.1 GAP86110.1 - 0.074 13.0 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 GAP86110.1 - 0.18 11.9 0.0 0.5 10.5 0.0 1.8 1 1 0 1 1 1 0 RNA helicase Aldedh PF00171.17 GAP86111.1 - 2.2e-143 477.9 1.4 2.4e-143 477.8 0.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAP86111.1 - 0.014 14.1 0.0 0.033 12.9 0.0 1.6 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) YiaAB PF05360.9 GAP86112.1 - 0.08 12.5 0.4 0.17 11.4 0.3 1.6 1 0 0 1 1 1 0 yiaA/B two helix domain Peptidase_M56 PF05569.6 GAP86112.1 - 0.09 11.7 0.1 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 RCR PF12273.3 GAP86112.1 - 0.62 10.6 3.7 1.1 9.7 2.6 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF917 PF06032.7 GAP86113.1 - 1.9e-109 365.4 0.7 3.5e-109 364.5 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 GAP86113.1 - 2.2e-52 177.9 7.7 4.2e-52 177.0 1.0 3.0 2 1 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 GAP86113.1 - 4.2e-28 98.0 0.0 1.4e-25 89.7 0.0 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 GAP86113.1 - 0.0016 16.8 0.4 0.021 13.1 0.0 2.4 2 0 0 2 2 2 1 MutL protein StbA PF06406.6 GAP86113.1 - 0.0044 16.0 0.2 1.3 7.8 0.0 2.5 2 0 0 2 2 2 2 StbA protein Ribosomal_L5_C PF00673.16 GAP86115.1 - 3.1e-22 78.1 0.0 4.2e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 GAP86115.1 - 2.3e-21 75.3 0.1 7e-21 73.7 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.17 GAP86116.1 - 9.6e-17 60.3 0.0 1.7e-16 59.5 0.0 1.3 1 1 0 1 1 1 1 LSM domain CPSase_L_D2 PF02786.12 GAP86117.1 - 2.6e-81 271.9 0.2 4e-81 271.3 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 GAP86117.1 - 2.8e-65 219.4 0.0 4.9e-65 218.6 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 GAP86117.1 - 8.3e-35 119.2 0.0 1.7e-34 118.2 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 GAP86117.1 - 2.8e-31 107.6 0.0 9.1e-31 106.0 0.0 2.0 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 GAP86117.1 - 7.7e-26 91.1 0.0 1.5e-25 90.2 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.17 GAP86117.1 - 6.5e-19 67.3 3.3 1.1e-18 66.6 1.1 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 GAP86117.1 - 1.1e-18 67.6 0.1 2.6e-18 66.4 0.1 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 GAP86117.1 - 6.8e-16 57.9 0.0 2.5e-15 56.0 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 GAP86117.1 - 5.1e-10 39.0 0.0 9.8e-10 38.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 GAP86117.1 - 9.5e-10 37.9 1.3 1.5e-06 27.7 0.0 3.2 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp PF02222.17 GAP86117.1 - 4.5e-07 29.3 0.0 8.4e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 GAP86117.1 - 2.7e-06 26.9 0.0 1.1e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 GAP86117.1 - 4.5e-05 23.3 0.0 9.5e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 GAP86117.1 - 0.00026 20.2 0.1 0.095 11.8 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein HlyD PF00529.15 GAP86117.1 - 0.00052 19.4 0.0 0.0032 16.8 0.0 2.1 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 GAP86117.1 - 0.0016 18.7 0.1 0.071 13.4 0.0 3.2 2 1 1 3 3 3 1 HlyD family secretion protein DUF2118 PF09891.4 GAP86117.1 - 0.021 14.5 0.0 0.056 13.1 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) GARS_A PF01071.14 GAP86117.1 - 0.061 12.8 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Rieske PF00355.21 GAP86117.1 - 0.13 11.8 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain Clathrin PF00637.15 GAP86118.1 - 3.3e-202 662.1 31.5 5.5e-32 110.3 1.2 7.5 8 0 0 8 8 8 7 Region in Clathrin and VPS TPR_12 PF13424.1 GAP86118.1 - 2.5e-07 30.5 4.4 0.44 10.5 0.0 7.0 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAP86118.1 - 3.1e-06 26.5 11.6 1.7 8.6 0.0 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 GAP86118.1 - 2.2e-05 24.6 12.1 13 6.7 0.1 9.7 10 1 1 11 11 11 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAP86118.1 - 0.00055 19.4 4.7 2.5 7.8 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAP86118.1 - 0.053 13.8 7.7 20 5.5 0.0 6.5 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAP86118.1 - 2.1 8.4 16.7 2.5 8.2 0.0 7.4 9 0 0 9 9 9 0 Tetratricopeptide repeat Clathrin_propel PF01394.15 GAP86119.1 - 2.3e-36 121.5 3.3 3.8e-05 23.6 0.0 7.2 7 0 0 7 7 7 7 Clathrin propeller repeat DUF1746 PF08508.5 GAP86120.1 - 2.2e-38 130.7 0.8 3.1e-38 130.2 0.6 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) RTC_insert PF05189.8 GAP86121.1 - 1e-29 102.5 0.0 2e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.16 GAP86121.1 - 3.3e-29 101.3 0.0 4.6e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Sec66 PF09802.4 GAP86122.1 - 4.3e-77 257.8 0.1 5e-77 257.6 0.1 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 RRM_1 PF00076.17 GAP86123.1 - 4.3e-12 45.5 0.0 1.8e-05 24.2 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP86123.1 - 1.3e-10 41.1 0.0 0.00013 21.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP86123.1 - 4.7e-05 23.1 0.0 0.00022 20.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF780 PF05611.6 GAP86123.1 - 2 9.1 14.1 0.084 13.5 2.2 2.4 2 0 0 2 2 2 0 Caenorhabditis elegans protein of unknown function (DUF780) DUF3405 PF11885.3 GAP86124.1 - 3.4e-203 675.3 0.4 4.2e-203 675.1 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) GCV_T PF01571.16 GAP86126.1 - 9.2e-61 204.8 0.1 1.3e-60 204.4 0.1 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 GAP86126.1 - 1.6e-22 79.2 0.1 4.6e-22 77.8 0.1 1.8 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain Arf PF00025.16 GAP86127.1 - 2.5e-80 267.8 0.3 2.8e-80 267.6 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 GAP86127.1 - 1.6e-14 53.5 0.0 2e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 GAP86127.1 - 2.4e-13 49.8 0.0 2.6e-13 49.6 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 GAP86127.1 - 2.2e-12 46.3 2.0 2.5e-09 36.3 0.5 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 GAP86127.1 - 3.5e-11 42.6 0.0 4.3e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 GAP86127.1 - 1.2e-08 35.4 0.0 1.8e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 GAP86127.1 - 2.5e-06 27.4 0.0 3.3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 GAP86127.1 - 0.009 15.1 0.7 0.02 13.9 0.5 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 GAP86127.1 - 0.012 15.0 0.2 0.093 12.1 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 GAP86127.1 - 0.04 13.7 0.2 0.097 12.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain EMP24_GP25L PF01105.19 GAP86128.1 - 9.8e-45 152.5 0.0 1.2e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Dioxygenase_C PF00775.16 GAP86128.1 - 0.007 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Sulfate_transp PF00916.15 GAP86129.1 - 8.9e-29 100.3 2.3 8.9e-29 100.3 1.6 1.7 2 0 0 2 2 2 1 Sulfate transporter family cNMP_binding PF00027.24 GAP86129.1 - 3e-16 59.0 0.0 5.3e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 GAP86129.1 - 2.4e-09 36.6 0.0 6e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 STAS domain Sld5 PF05916.6 GAP86130.1 - 7.2e-12 45.5 0.0 1.2e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein AICARFT_IMPCHas PF01808.13 GAP86131.1 - 8.1e-110 366.7 0.1 1.3e-109 366.0 0.1 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 GAP86131.1 - 2.8e-24 84.8 0.0 6e-24 83.7 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain EF1_GNE PF00736.14 GAP86132.1 - 3.1e-27 94.0 0.5 5.3e-27 93.3 0.4 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 GAP86132.1 - 1.8e-14 53.5 6.7 1.8e-14 53.5 4.6 2.2 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 GAP86132.1 - 0.00048 20.5 0.0 0.0012 19.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAP86132.1 - 0.00051 19.9 0.2 0.0017 18.2 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Spc7_N PF15402.1 GAP86132.1 - 0.041 11.9 0.4 0.054 11.5 0.3 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 GST_C_2 PF13410.1 GAP86132.1 - 0.22 11.4 1.4 4.4 7.2 1.0 2.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AAA_2 PF07724.9 GAP86133.1 - 2.5e-44 151.2 0.0 3.4e-43 147.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 GAP86133.1 - 3.2e-24 84.6 0.5 3.2e-24 84.6 0.3 2.3 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 GAP86133.1 - 6.5e-19 68.4 0.1 6.3e-10 39.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAP86133.1 - 4.2e-12 45.9 0.0 1.1e-08 34.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAP86133.1 - 1.5e-11 44.6 10.1 0.00021 21.3 0.0 5.1 4 2 2 6 6 5 3 AAA ATPase domain AAA_22 PF13401.1 GAP86133.1 - 1.7e-09 37.9 2.4 0.0014 18.7 0.0 3.9 3 2 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 GAP86133.1 - 4.8e-07 29.3 0.2 0.00013 21.4 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.7 GAP86133.1 - 3.8e-06 26.6 0.1 0.09 12.4 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_17 PF13207.1 GAP86133.1 - 1e-05 26.3 3.0 0.0089 16.8 0.0 4.0 4 0 0 4 4 4 1 AAA domain AAA_14 PF13173.1 GAP86133.1 - 1.8e-05 24.6 0.0 0.066 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 GAP86133.1 - 2.4e-05 24.1 5.2 1.3 8.6 0.0 4.4 2 2 2 4 4 4 3 Archaeal ATPase AAA_18 PF13238.1 GAP86133.1 - 4.8e-05 23.6 6.3 0.064 13.5 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_19 PF13245.1 GAP86133.1 - 0.00025 20.7 0.0 0.036 13.8 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain MobB PF03205.9 GAP86133.1 - 0.00052 19.7 0.1 0.077 12.7 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 GAP86133.1 - 0.00098 18.5 0.0 1.4 8.2 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 GAP86133.1 - 0.0015 18.6 0.0 0.32 11.1 0.0 2.9 2 1 0 2 2 2 1 RNA helicase ABC_tran PF00005.22 GAP86133.1 - 0.0019 18.5 2.1 0.62 10.3 0.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_28 PF13521.1 GAP86133.1 - 0.002 18.1 0.4 5.9 6.8 0.0 3.7 3 1 0 3 3 3 0 AAA domain IncA PF04156.9 GAP86133.1 - 0.0026 17.3 8.4 0.0068 16.0 5.8 1.6 1 0 0 1 1 1 1 IncA protein SRP54 PF00448.17 GAP86133.1 - 0.0031 16.9 0.0 0.13 11.6 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 GAP86133.1 - 0.0032 16.9 0.0 0.9 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 GAP86133.1 - 0.0043 16.2 0.0 0.72 9.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 GAP86133.1 - 0.0082 15.6 0.0 0.4 10.0 0.0 3.2 2 2 0 2 2 2 1 AAA-like domain UvrD-helicase PF00580.16 GAP86133.1 - 0.0083 15.4 1.1 0.35 10.1 0.1 2.3 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Mg_chelatase PF01078.16 GAP86133.1 - 0.0089 15.2 0.0 2.5 7.2 0.0 3.1 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI PhoH PF02562.11 GAP86133.1 - 0.013 14.7 0.0 0.56 9.3 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein TrwB_AAD_bind PF10412.4 GAP86133.1 - 0.015 13.9 0.0 2.5 6.6 0.0 2.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.1 GAP86133.1 - 0.017 14.6 0.1 0.94 9.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.8 GAP86133.1 - 0.029 13.3 0.2 1.1 8.0 0.2 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF815) APG6 PF04111.7 GAP86133.1 - 0.031 13.3 5.6 0.049 12.6 3.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_24 PF13479.1 GAP86133.1 - 0.033 13.7 0.0 0.98 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 GAP86133.1 - 0.041 13.7 0.0 4.6 7.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.9 GAP86133.1 - 0.06 12.2 0.0 1.3 7.8 0.0 2.4 3 0 0 3 3 2 0 PIF1-like helicase CENP-F_leu_zip PF10473.4 GAP86133.1 - 0.063 13.1 19.3 0.094 12.5 11.6 2.5 2 1 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Miro PF08477.8 GAP86133.1 - 0.072 13.5 0.1 2.6 8.5 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein UPF0079 PF02367.12 GAP86133.1 - 0.083 12.5 0.0 11 5.7 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 GAP86133.1 - 0.09 12.2 0.0 2 7.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.10 GAP86133.1 - 0.12 12.2 3.8 5.4 6.8 0.0 3.4 3 2 1 4 4 2 0 Type III restriction enzyme, res subunit ATP_bind_1 PF03029.12 GAP86133.1 - 0.13 11.7 0.0 0.74 9.3 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 GAP86133.1 - 0.18 11.3 0.0 9.3 5.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Mnd1 PF03962.10 GAP86133.1 - 0.79 9.3 12.6 1.5 8.4 8.7 1.4 1 0 0 1 1 1 0 Mnd1 family OmpH PF03938.9 GAP86133.1 - 1.1 9.1 8.4 2.8 7.8 5.9 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Cortex-I_coil PF09304.5 GAP86133.1 - 4.8 7.2 18.6 2.1 8.4 9.0 2.6 2 0 0 2 2 2 0 Cortexillin I, coiled coil V_ATPase_I PF01496.14 GAP86133.1 - 5.5 4.7 4.7 8 4.1 3.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.1 GAP86133.1 - 5.9 7.1 21.7 1.8e+02 2.3 0.0 3.2 2 1 0 2 2 2 0 AAA domain OEP PF02321.13 GAP86133.1 - 6 6.4 10.3 14 5.2 7.1 1.6 1 0 0 1 1 1 0 Outer membrane efflux protein Atg14 PF10186.4 GAP86133.1 - 8.3 5.2 10.1 16 4.3 7.0 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DEAD PF00270.24 GAP86134.1 - 1.2e-25 89.9 0.0 2.1e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 GAP86134.1 - 4.2e-13 49.6 0.1 1.4e-12 48.0 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 GAP86134.1 - 3.2e-10 39.7 0.1 1.3e-09 37.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CDT1 PF08839.6 GAP86134.1 - 0.047 13.6 0.0 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 DNA replication factor CDT1 like Ran_BP1 PF00638.13 GAP86135.1 - 4.4e-13 49.3 0.1 1.4e-05 25.0 0.1 2.5 2 0 0 2 2 2 2 RanBP1 domain WH1 PF00568.18 GAP86135.1 - 0.036 13.7 0.0 0.66 9.7 0.0 2.2 2 0 0 2 2 2 0 WH1 domain Chitin_synth_2 PF03142.10 GAP86136.1 - 6.3e-24 84.2 4.1 1.7e-21 76.2 1.7 2.5 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 GAP86136.1 - 6.8e-19 68.3 5.2 6.8e-19 68.3 3.6 2.5 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAP86136.1 - 1.5e-18 67.4 0.0 3.4e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 GAP86136.1 - 0.0089 15.7 0.1 4.1 7.0 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 PH_3 PF14593.1 GAP86136.1 - 0.096 12.5 0.3 0.61 9.9 0.0 2.4 3 0 0 3 3 3 0 PH domain MIF4G PF02854.14 GAP86137.1 - 8.3e-56 188.7 0.0 6e-26 91.1 0.0 3.4 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 GAP86137.1 - 1e-51 175.0 21.1 3.2e-51 173.5 14.6 1.9 1 1 0 1 1 1 1 Up-frameshift suppressor 2 Mo-co_dimer PF03404.11 GAP86138.1 - 4.2e-56 188.1 0.3 1.4e-55 186.5 0.0 2.1 3 0 0 3 3 3 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 GAP86138.1 - 3.2e-50 169.8 0.0 5e-50 169.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 GAP86138.1 - 1.1e-28 99.2 0.0 1.9e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 GAP86138.1 - 5.2e-23 80.6 0.0 1.7e-22 78.9 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.16 GAP86138.1 - 1.5e-20 73.7 0.0 2.9e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 GAP86138.1 - 0.0055 16.6 0.0 0.06 13.2 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Thioredoxin_4 PF13462.1 GAP86138.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Pyr_redox_2 PF07992.9 GAP86139.1 - 1.4e-19 70.7 0.0 2.1e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAP86139.1 - 1.5e-13 50.9 0.0 6.3e-11 42.5 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 GAP86139.1 - 1.8e-06 26.8 0.2 4.7e-06 25.5 0.2 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 GAP86139.1 - 5.1e-06 26.5 0.1 1.2e-05 25.3 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 GAP86139.1 - 1.5e-05 24.5 0.5 5.4e-05 22.7 0.4 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 GAP86139.1 - 3.3e-05 23.0 1.4 9.1e-05 21.6 1.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 GAP86139.1 - 0.053 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair Pyr_redox_3 PF13738.1 GAP86139.1 - 0.083 12.9 0.1 26 4.7 0.0 2.6 2 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Nop53 PF07767.6 GAP86140.1 - 1.5e-96 323.7 23.9 1.8e-96 323.5 16.6 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) FLO_LFY PF01698.11 GAP86140.1 - 4.1 6.1 17.0 7.4 5.3 11.8 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein Ras PF00071.17 GAP86141.1 - 4.1e-59 198.6 0.4 5.3e-59 198.2 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAP86141.1 - 1.4e-21 77.2 0.2 2.5e-21 76.3 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAP86141.1 - 1.5e-17 63.3 0.4 1.9e-17 63.0 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAP86141.1 - 1.3e-07 31.2 0.1 5.6e-07 29.1 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAP86141.1 - 1.8e-06 27.2 0.4 2.3e-06 26.9 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAP86141.1 - 7.2e-06 25.9 0.0 1.3e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 GAP86141.1 - 1.1e-05 24.7 0.1 1.4e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 GAP86141.1 - 0.02 14.8 0.0 1.5 8.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 GAP86141.1 - 0.026 14.3 0.2 3 7.6 0.0 2.6 2 1 0 2 2 2 0 Dynamin family AAA_14 PF13173.1 GAP86141.1 - 0.076 12.9 0.3 0.14 12.0 0.2 1.5 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 GAP86141.1 - 0.078 12.6 0.2 4 7.1 0.0 2.4 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Rib_5-P_isom_A PF06026.9 GAP86142.1 - 1.1e-37 129.0 0.0 1.8e-36 125.0 0.0 2.3 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) NIR_SIR PF01077.17 GAP86143.1 - 5.9e-54 181.6 0.1 1.6e-47 160.7 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 GAP86143.1 - 3.6e-29 100.1 0.0 3.6e-14 52.1 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 GAP86143.1 - 3.9e-28 98.2 0.0 8.9e-28 97.0 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 GAP86143.1 - 5.3e-06 26.1 0.3 1.8e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Longin PF13774.1 GAP86144.1 - 0.044 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Regulated-SNARE-like domain Usp PF00582.21 GAP86144.1 - 0.1 12.8 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Universal stress protein family Lipase_3 PF01764.20 GAP86145.1 - 1.1e-32 112.5 0.0 1.5e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 GAP86145.1 - 0.013 14.8 0.1 1 8.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 GAP86145.1 - 0.018 14.8 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 GAP86145.1 - 0.21 11.1 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein 14-3-3 PF00244.15 GAP86146.1 - 2.7e-114 380.1 1.0 3.2e-114 379.8 0.7 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 GAP86146.1 - 0.025 14.4 0.4 9.9 6.1 0.0 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF837 PF05769.6 GAP86146.1 - 0.054 13.0 0.3 13 5.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF837) HisKA PF00512.20 GAP86146.1 - 0.26 11.3 1.1 23 5.0 0.0 3.3 4 0 0 4 4 4 0 His Kinase A (phospho-acceptor) domain Syja_N PF02383.13 GAP86147.1 - 1.6e-83 280.1 0.0 2.5e-83 279.5 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 GAP86147.1 - 3.1e-24 86.2 0.0 5.1e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PRP38_assoc PF12871.2 GAP86148.1 - 0.82 10.2 15.0 0.16 12.5 0.4 2.5 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Med3 PF11593.3 GAP86148.1 - 3.4 6.8 5.2 3.5 6.7 0.5 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal TPR_16 PF13432.1 GAP86149.1 - 2.5e-06 28.0 0.3 0.00046 20.7 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAP86149.1 - 0.00053 20.3 4.9 0.94 10.2 0.0 5.8 4 2 2 6 6 6 1 Tetratricopeptide repeat Suf PF05843.9 GAP86149.1 - 0.0053 16.5 5.0 5.9 6.5 0.1 3.8 3 1 1 4 4 4 3 Suppressor of forked protein (Suf) peroxidase PF00141.18 GAP86150.1 - 2e-50 171.4 0.0 3.6e-50 170.6 0.0 1.4 1 0 0 1 1 1 1 Peroxidase PAN_3 PF08277.7 GAP86151.1 - 0.011 15.3 2.1 0.011 15.3 1.4 2.3 3 0 0 3 3 3 0 PAN-like domain PAN_1 PF00024.21 GAP86151.1 - 0.018 14.8 3.3 0.021 14.5 0.7 2.3 2 0 0 2 2 2 0 PAN domain PAN_4 PF14295.1 GAP86151.1 - 0.019 14.6 3.3 0.026 14.2 1.3 1.9 2 0 0 2 2 2 0 PAN domain RHS PF03527.9 GAP86151.1 - 0.16 11.7 0.8 0.34 10.7 0.5 1.5 1 0 0 1 1 1 0 RHS protein ATP11 PF06644.6 GAP86152.1 - 3.1e-42 144.9 0.0 5e-15 55.7 0.0 3.1 3 0 0 3 3 3 3 ATP11 protein DUF3439 PF11921.3 GAP86152.1 - 0.058 13.1 9.4 0.095 12.4 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 GAP86152.1 - 0.12 12.1 14.6 0.22 11.3 10.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 GAP86152.1 - 1.5 6.6 17.7 0.23 9.3 9.4 1.6 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.7 GAP86152.1 - 2.5 5.7 5.5 3.3 5.3 3.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AMP-binding PF00501.23 GAP86153.1 - 5.5e-91 305.0 0.0 6.4e-91 304.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAP86153.1 - 6.6e-13 49.4 0.1 1.2e-12 48.6 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SpecificRecomb PF10136.4 GAP86153.1 - 0.019 13.0 0.3 0.025 12.6 0.2 1.1 1 0 0 1 1 1 0 Site-specific recombinase Abhydro_lipase PF04083.11 GAP86154.1 - 7.9e-20 69.9 0.0 1.6e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 GAP86154.1 - 2.4e-05 24.3 0.3 4.7e-05 23.3 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP86154.1 - 0.00022 20.9 0.0 0.00051 19.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP86154.1 - 0.03 13.8 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.9 GAP86154.1 - 0.21 10.8 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AAA PF00004.24 GAP86155.1 - 1.2e-48 164.6 0.0 4.9e-43 146.4 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 GAP86155.1 - 4.5e-05 22.9 0.1 0.00037 19.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAP86155.1 - 0.00011 23.0 0.0 0.00044 21.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 GAP86155.1 - 0.00024 20.2 0.0 0.00059 18.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 GAP86155.1 - 0.00061 19.8 0.1 0.024 14.6 0.0 2.9 1 1 1 2 2 2 1 AAA ATPase domain Parvo_NS1 PF01057.12 GAP86155.1 - 0.00065 18.6 0.0 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_22 PF13401.1 GAP86155.1 - 0.00073 19.6 0.0 0.0046 17.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 GAP86155.1 - 0.001 18.5 0.0 0.0023 17.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 GAP86155.1 - 0.0028 17.5 0.0 0.0074 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 GAP86155.1 - 0.0029 17.3 0.1 0.017 14.8 0.0 2.4 2 0 0 2 2 1 1 Part of AAA domain TIP49 PF06068.8 GAP86155.1 - 0.0058 15.3 0.0 0.016 13.9 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus RNA_helicase PF00910.17 GAP86155.1 - 0.0092 16.1 0.0 0.033 14.3 0.0 2.0 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.16 GAP86155.1 - 0.017 14.2 0.0 0.043 12.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 GAP86155.1 - 0.02 14.5 0.0 0.082 12.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 GAP86155.1 - 0.031 13.4 0.0 0.071 12.2 0.0 1.5 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 GAP86155.1 - 0.031 13.4 0.0 0.076 12.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.1 GAP86155.1 - 0.051 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 GAP86155.1 - 0.065 13.1 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 GAP86155.1 - 0.075 12.9 0.0 0.23 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAP86155.1 - 0.078 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 GAP86155.1 - 0.084 11.7 0.2 0.18 10.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PPV_E1_C PF00519.12 GAP86155.1 - 0.26 9.8 0.0 0.42 9.1 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase SH3BGR PF04908.10 GAP86156.1 - 0.00014 21.7 0.0 0.00043 20.1 0.0 2.0 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein TFIIA PF03153.8 GAP86156.1 - 0.00041 20.3 32.0 0.00054 19.9 22.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 GAP86156.1 - 0.0015 16.5 31.4 0.002 16.1 21.8 1.1 1 0 0 1 1 1 1 Nop14-like family Nucleoplasmin PF03066.10 GAP86157.1 - 1.2 8.6 7.6 1.6 8.2 5.3 1.2 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 GAP86157.1 - 2.8 6.5 13.5 3.1 6.4 9.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PBP1_TM PF14812.1 GAP86157.1 - 5.5 7.3 7.8 7.9 6.8 5.4 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Phe_tRNA-synt_N PF02912.13 GAP86158.1 - 0.074 12.7 0.8 0.074 12.7 0.6 2.2 2 1 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain DUF2390 PF09523.5 GAP86158.1 - 0.14 12.2 0.2 0.14 12.2 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2390) DUF883 PF05957.8 GAP86158.1 - 8.7 6.8 11.7 0.56 10.6 0.5 2.4 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Glyco_hydro_16 PF00722.16 GAP86159.1 - 3.7e-09 36.1 0.0 1.1e-08 34.5 0.0 1.8 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Glyco_transf_34 PF05637.7 GAP86160.1 - 1.9e-64 217.4 1.1 2.7e-64 216.9 0.8 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF454 PF04304.8 GAP86160.1 - 0.02 14.8 0.8 0.045 13.7 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF454) Nucleotid_trans PF03407.11 GAP86160.1 - 0.078 12.7 0.2 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Halogen_Hydrol PF10112.4 GAP86161.1 - 1.3 8.4 2.2 2 7.7 0.4 2.1 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF4491 PF14898.1 GAP86161.1 - 3.7 7.7 0.0 6.6 6.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) Fungal_trans PF04082.13 GAP86162.1 - 8.4e-12 44.5 0.0 1.4e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP86162.1 - 1.1e-07 31.6 9.8 2.1e-07 30.7 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ARL6IP6 PF15062.1 GAP86162.1 - 1.9 8.4 5.2 5.8 6.8 0.2 2.5 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix URO-D PF01208.12 GAP86164.1 - 1e-90 304.1 0.0 1.3e-90 303.8 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Acetyltransf_10 PF13673.1 GAP86165.1 - 0.00024 21.2 0.0 0.00057 19.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAP86165.1 - 0.00026 20.7 0.0 0.00054 19.6 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein DUF3602 PF12223.3 GAP86166.1 - 2.6e-16 59.7 17.5 7.7e-14 51.8 2.7 3.0 1 1 2 3 3 3 2 Protein of unknown function (DUF3602) Speriolin_N PF15058.1 GAP86166.1 - 0.29 11.0 3.0 0.36 10.7 0.6 1.9 2 0 0 2 2 2 0 Speriolin N terminus Velvet PF11754.3 GAP86167.1 - 4.8e-73 245.1 0.0 6.4e-73 244.6 0.0 1.1 1 0 0 1 1 1 1 Velvet factor RhoGEF PF00621.15 GAP86168.1 - 1.2e-35 122.9 0.5 1.2e-35 122.9 0.3 2.1 2 0 0 2 2 2 1 RhoGEF domain BAR PF03114.13 GAP86168.1 - 2.7e-10 40.1 1.1 2.7e-10 40.1 0.8 2.6 3 0 0 3 3 3 1 BAR domain Telomerase_RBD PF12009.3 GAP86169.1 - 8e-42 142.3 4.2 1.3e-41 141.7 2.2 1.9 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 GAP86169.1 - 1.1e-14 54.3 0.1 4.1e-13 49.1 0.1 2.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Alkyl_sulf_dimr PF14863.1 GAP86170.1 - 0.012 15.8 0.0 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation Peptidase_C48 PF02902.14 GAP86171.1 - 9.2e-18 64.6 0.7 4.4e-17 62.4 0.5 2.0 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF1640 PF07798.6 GAP86172.1 - 1.1e-63 214.4 8.1 1.1e-63 214.4 5.6 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) Syntaxin PF00804.20 GAP86172.1 - 0.063 13.4 8.5 0.66 10.1 5.9 2.5 1 1 0 1 1 1 0 Syntaxin CPSase_L_D2 PF02786.12 GAP86173.1 - 2.4e-110 366.8 0.0 2.5e-84 281.8 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 GAP86173.1 - 7.5e-41 138.7 0.0 1.8e-40 137.5 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 GAP86173.1 - 2.8e-40 138.0 0.1 2.2e-22 79.6 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 GAP86173.1 - 1.2e-24 86.4 0.0 1.7e-15 57.0 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 GAP86173.1 - 6.5e-24 84.2 0.0 3.8e-09 35.7 0.0 3.7 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 GAP86173.1 - 1.8e-19 69.7 0.1 1e-08 34.7 0.0 3.0 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 GAP86173.1 - 4.5e-18 65.3 0.2 1.1e-08 34.7 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 GAP86173.1 - 1e-07 31.6 0.0 0.00023 20.7 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 GAP86173.1 - 8.6e-06 25.6 0.2 0.097 12.5 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 GAP86173.1 - 8.5e-05 22.1 0.2 0.33 10.4 0.0 2.6 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 GAP86173.1 - 0.0012 18.0 0.1 1.4 8.0 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain NPL4 PF05021.10 GAP86174.1 - 5.8e-128 426.3 0.0 7.1e-128 426.0 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 GAP86174.1 - 3.7e-68 227.7 0.1 5.6e-68 227.2 0.0 1.2 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 GAP86174.1 - 0.00085 19.5 0.0 0.002 18.3 0.0 1.7 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 DUF2417 PF10329.4 GAP86175.1 - 6.6e-80 267.8 0.5 8.6e-80 267.4 0.4 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 GAP86175.1 - 2.4e-07 30.8 1.2 3.8e-07 30.2 0.2 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2269 PF10027.4 GAP86175.1 - 0.26 11.0 13.6 0.95 9.2 9.4 1.9 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2269) SLX9 PF15341.1 GAP86176.1 - 3.1e-36 124.4 4.8 4.7e-36 123.8 3.4 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 MRP-S31 PF15433.1 GAP86176.1 - 0.041 13.3 1.2 0.048 13.0 0.8 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 MBOAT_2 PF13813.1 GAP86177.1 - 1.4e-14 53.8 1.7 1.4e-14 53.8 1.2 2.6 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family HisG PF01634.13 GAP86178.1 - 2.3e-50 170.3 0.1 2.7e-40 137.6 0.0 2.3 1 1 1 2 2 2 2 ATP phosphoribosyltransferase HisG_C PF08029.6 GAP86178.1 - 6.1e-27 93.3 0.1 1.1e-26 92.5 0.1 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 GAP86178.1 - 0.009 15.6 0.0 0.41 10.1 0.0 2.3 2 0 0 2 2 2 1 NMT1/THI5 like MFS_2 PF13347.1 GAP86179.1 - 1.5e-11 43.4 9.3 1.5e-11 43.4 6.4 2.8 3 0 0 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.2 GAP86179.1 - 0.0095 15.7 3.1 0.088 12.6 0.0 3.2 2 0 0 2 2 2 1 MFS_1 like family XhlA PF10779.4 GAP86179.1 - 0.19 11.6 0.2 0.7 9.8 0.1 2.0 1 0 0 1 1 1 0 Haemolysin XhlA AAA PF00004.24 GAP86180.1 - 1.4e-15 57.6 0.0 3.2e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 GAP86180.1 - 4.1e-13 49.3 0.0 2.2e-07 30.6 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.10 GAP86180.1 - 5e-12 45.2 0.0 1.4e-08 33.8 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 GAP86180.1 - 4.6e-10 39.3 0.0 1.4e-09 37.7 0.0 1.8 2 0 0 2 2 2 1 Replication factor C C-terminal domain RuvB_N PF05496.7 GAP86180.1 - 3.6e-07 29.4 0.0 1.6e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 GAP86180.1 - 1e-06 28.9 0.1 0.00036 20.6 0.0 3.1 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAP86180.1 - 1.1e-05 25.5 0.1 0.00075 19.5 0.0 3.2 2 2 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 GAP86180.1 - 1.8e-05 24.4 0.0 4.2e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 GAP86180.1 - 2.8e-05 23.7 0.0 5.3e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 GAP86180.1 - 0.00017 20.8 0.0 0.0066 15.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 GAP86180.1 - 0.00027 20.8 0.0 0.00049 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 GAP86180.1 - 0.00039 19.9 0.0 0.00066 19.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_17 PF13207.1 GAP86180.1 - 0.0016 19.2 0.0 0.0051 17.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 GAP86180.1 - 0.0022 17.0 0.0 0.0043 16.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.1 GAP86180.1 - 0.0031 17.1 0.0 0.0067 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 GAP86180.1 - 0.0031 16.4 0.0 0.0049 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 GAP86180.1 - 0.0049 16.2 0.0 0.024 14.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 GAP86180.1 - 0.0059 15.3 0.0 0.41 9.3 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus FtsK_SpoIIIE PF01580.13 GAP86180.1 - 0.007 15.8 0.0 0.019 14.4 0.0 1.8 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_5 PF07728.9 GAP86180.1 - 0.0098 15.6 0.2 0.088 12.5 0.1 2.5 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 GAP86180.1 - 0.02 14.8 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAP86180.1 - 0.027 14.7 0.0 0.059 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 GAP86180.1 - 0.029 14.2 0.0 0.13 12.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 GAP86180.1 - 0.034 13.7 0.0 0.42 10.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 GAP86180.1 - 0.038 13.4 0.2 0.81 9.0 0.0 2.5 2 1 1 3 3 3 0 AAA-like domain AAA_3 PF07726.6 GAP86180.1 - 0.05 13.2 0.0 0.31 10.6 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 GAP86180.1 - 0.075 12.8 0.0 0.25 11.1 0.0 1.9 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 GAP86180.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase SNF2_N PF00176.18 GAP86180.1 - 0.13 11.0 0.0 3.6 6.2 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain DUF1212 PF06738.7 GAP86181.1 - 0.11 11.9 0.1 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) DUF664 PF04978.7 GAP86181.1 - 0.87 9.8 6.8 0.44 10.7 0.2 3.5 3 2 1 4 4 4 0 Protein of unknown function (DUF664) Sec63 PF02889.11 GAP86182.1 - 1.2e-188 625.9 0.0 1.2e-102 343.3 0.0 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 GAP86182.1 - 7.7e-53 178.4 0.1 2e-30 105.4 0.1 3.7 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 GAP86182.1 - 2.2e-17 63.4 0.0 1e-08 35.2 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 GAP86182.1 - 1.6e-11 43.8 0.0 8.2e-09 35.2 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 GAP86182.1 - 9.3e-09 35.5 0.2 8.8e-05 22.6 0.0 3.1 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 GAP86182.1 - 0.00034 19.9 0.0 0.12 11.5 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_10 PF12846.2 GAP86182.1 - 0.00073 19.0 0.1 4.2 6.7 0.0 4.2 5 0 0 5 5 5 2 AAA-like domain T2SE PF00437.15 GAP86182.1 - 0.00098 18.1 0.0 1.5 7.6 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_19 PF13245.1 GAP86182.1 - 0.0032 17.1 0.0 0.44 10.3 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_23 PF13476.1 GAP86182.1 - 0.0055 17.0 1.1 3.1 8.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 GAP86182.1 - 0.024 14.1 0.0 0.92 8.9 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family PWWP PF00855.12 GAP86183.1 - 4.9e-13 49.0 0.6 2.5e-12 46.8 0.0 2.5 2 0 0 2 2 2 1 PWWP domain DUF1299 PF06975.6 GAP86183.1 - 0.0037 17.0 1.5 0.0037 17.0 1.0 5.0 6 0 0 6 6 6 2 Protein of unknown function (DUF1299) UQ_con PF00179.21 GAP86185.1 - 1.3e-44 151.0 0.0 3.5e-30 104.2 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme RWD PF05773.17 GAP86185.1 - 0.0016 18.2 0.0 0.29 11.0 0.0 2.6 2 1 0 2 2 2 2 RWD domain UEV PF05743.8 GAP86185.1 - 0.013 15.1 0.0 0.031 13.9 0.0 1.6 1 0 0 1 1 1 0 UEV domain DUF2680 PF10925.3 GAP86185.1 - 0.18 11.7 0.7 21 5.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2680) 3Beta_HSD PF01073.14 GAP86186.1 - 3.2e-67 226.1 0.0 4.1e-67 225.8 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAP86186.1 - 9.7e-33 113.5 0.2 1.4e-32 113.0 0.2 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAP86186.1 - 2.4e-16 59.4 1.1 2.8e-14 52.6 0.8 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 GAP86186.1 - 4.1e-14 52.9 0.0 7.6e-14 52.1 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 GAP86186.1 - 6.6e-14 51.4 0.2 9.1e-14 51.0 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 GAP86186.1 - 2.5e-07 29.9 0.0 1.1e-06 27.7 0.0 2.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 GAP86186.1 - 8.9e-07 28.9 0.2 3e-06 27.2 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase TrkA_N PF02254.13 GAP86186.1 - 3.4e-06 27.0 0.1 0.00022 21.2 0.0 2.6 1 1 1 2 2 2 1 TrkA-N domain KR PF08659.5 GAP86186.1 - 8.8e-05 22.2 0.2 0.00029 20.5 0.1 1.9 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 GAP86186.1 - 0.00025 20.4 0.0 0.00047 19.4 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family NAD_binding_3 PF03447.11 GAP86186.1 - 0.1 12.9 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain RhoGAP PF00620.22 GAP86187.1 - 6.7e-39 132.9 0.0 1.8e-38 131.5 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 GAP86187.1 - 2.8e-32 110.5 42.1 2.3e-12 46.8 5.2 5.0 5 0 0 5 5 5 4 LIM domain zf-ribbon_3 PF13248.1 GAP86187.1 - 0.83 8.9 9.9 4 6.7 0.0 4.0 4 0 0 4 4 4 0 zinc-ribbon domain Terminase_GpA PF05876.7 GAP86187.1 - 1.1 7.5 4.9 2.7 6.2 3.4 1.5 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Yippee-Mis18 PF03226.9 GAP86187.1 - 7.3 6.7 21.0 0.12 12.4 2.6 4.1 3 1 1 4 4 4 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HMG_box PF00505.14 GAP86188.1 - 4.2e-05 23.7 0.3 4.2e-05 23.7 0.2 2.7 3 1 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 GAP86188.1 - 0.0002 21.6 0.9 0.00058 20.1 0.0 2.1 2 0 0 2 2 2 1 HMG-box domain Transposase_24 PF03004.9 GAP86188.1 - 0.078 12.8 7.0 0.053 13.4 1.0 2.7 1 1 2 3 3 3 0 Plant transposase (Ptta/En/Spm family) DEAD PF00270.24 GAP86189.1 - 6.6e-46 155.8 0.0 5.8e-45 152.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP86189.1 - 4.7e-24 84.0 0.0 1e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 GAP86189.1 - 0.00058 18.7 0.0 0.0011 17.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-H2C2_2 PF13465.1 GAP86190.1 - 4.9e-24 83.3 23.6 2.6e-08 33.7 0.1 5.8 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 GAP86190.1 - 1.2e-19 69.4 29.8 1.9e-05 24.7 0.3 6.9 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP86190.1 - 1.9e-13 49.7 29.2 0.015 15.6 0.2 6.8 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_6 PF13912.1 GAP86190.1 - 1.4e-06 27.9 19.5 0.0011 18.8 0.6 4.9 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAP86190.1 - 6.6e-05 22.9 6.6 0.37 10.9 0.0 5.1 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 GAP86190.1 - 0.00071 19.1 6.2 2 8.1 0.1 3.8 3 0 0 3 3 3 3 zinc-finger of a C2HC-type zf-met PF12874.2 GAP86190.1 - 0.0064 16.6 0.5 0.0064 16.6 0.3 4.5 6 0 0 6 6 6 1 Zinc-finger of C2H2 type Ribosomal_L29 PF00831.18 GAP86191.1 - 2.5e-17 62.3 0.7 2.5e-17 62.3 0.5 2.1 2 1 0 2 2 2 1 Ribosomal L29 protein V-SNARE_C PF12352.3 GAP86192.1 - 2.3e-13 50.0 0.5 2.3e-13 50.0 0.4 2.9 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus YjgP_YjgQ PF03739.9 GAP86192.1 - 0.025 13.3 0.3 0.032 12.9 0.2 1.3 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family Surfac_D-trimer PF09006.6 GAP86192.1 - 0.068 12.8 0.0 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation Erp_C PF06780.6 GAP86192.1 - 0.19 11.5 1.8 0.33 10.7 1.2 1.5 1 0 0 1 1 1 0 Erp protein C-terminus STAT_alpha PF01017.15 GAP86192.1 - 0.31 10.7 9.2 0.93 9.1 1.0 2.4 1 1 1 2 2 2 0 STAT protein, all-alpha domain DUF2450 PF10475.4 GAP86192.1 - 1.3 7.8 5.5 5.1 5.8 2.0 2.3 1 1 1 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) Uds1 PF15456.1 GAP86192.1 - 1.3 8.9 14.3 0.73 9.8 5.0 2.5 1 1 1 2 2 2 0 Up-regulated During Septation KxDL PF10241.4 GAP86192.1 - 2.9 7.8 7.1 1.1 9.2 2.3 2.3 3 0 0 3 3 3 0 Uncharacterized conserved protein FTA4 PF13093.1 GAP86192.1 - 3.3 7.0 13.6 8.1 5.8 9.5 1.7 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Adeno_PIX PF03955.9 GAP86192.1 - 3.5 8.1 6.8 4.4 7.8 0.8 2.4 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) IncA PF04156.9 GAP86192.1 - 6.2 6.3 17.1 14 5.1 9.7 2.2 1 1 1 2 2 2 0 IncA protein DUF4164 PF13747.1 GAP86192.1 - 7.3 6.8 15.1 10 6.3 6.4 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) CorA PF01544.13 GAP86192.1 - 8.5 5.3 12.5 5.1 6.0 0.5 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF342 PF03961.8 GAP86192.1 - 9.6 4.4 7.5 15 3.8 3.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) PilO PF04350.8 GAP86192.1 - 9.7 6.0 7.9 2.2 8.1 0.9 2.6 1 1 0 3 3 3 0 Pilus assembly protein, PilO ATP-synt_10 PF05176.9 GAP86193.1 - 4.3e-56 189.9 0.0 4.9e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein 2-oxoacid_dh PF00198.18 GAP86194.1 - 9.9e-76 254.0 0.2 1.3e-75 253.6 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 GAP86194.1 - 4.5e-16 58.2 0.1 9.6e-16 57.1 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 GAP86194.1 - 8.4e-11 41.3 0.0 1.8e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain SKI PF01202.17 GAP86195.1 - 5.3e-12 45.8 0.0 6.5e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.1 GAP86195.1 - 6.2e-11 42.3 0.0 8e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAP86195.1 - 1.3e-10 42.1 0.0 1.7e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAP86195.1 - 6.5e-09 36.1 0.0 1.6e-08 34.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.10 GAP86195.1 - 4.1e-05 22.4 0.0 5.4e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_28 PF13521.1 GAP86195.1 - 6.9e-05 22.8 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAP86195.1 - 0.0007 19.7 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 GAP86195.1 - 0.0012 19.0 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 GAP86195.1 - 0.0017 18.0 0.0 0.0035 17.0 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 GAP86195.1 - 0.0021 17.2 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 GAP86195.1 - 0.0028 17.6 0.1 0.0055 16.7 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 GAP86195.1 - 0.0031 17.2 0.0 0.0055 16.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_5 PF07728.9 GAP86195.1 - 0.0035 17.0 0.0 0.0056 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 GAP86195.1 - 0.0068 16.3 0.0 0.01 15.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 GAP86195.1 - 0.0077 15.8 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Cytidylate_kin2 PF13189.1 GAP86195.1 - 0.012 15.4 0.0 0.068 13.0 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase-like family NTPase_1 PF03266.10 GAP86195.1 - 0.012 15.2 0.1 0.037 13.7 0.0 1.7 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.17 GAP86195.1 - 0.014 15.5 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 RNA helicase CoaE PF01121.15 GAP86195.1 - 0.016 14.5 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_24 PF13479.1 GAP86195.1 - 0.022 14.3 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 GAP86195.1 - 0.022 14.4 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.1 GAP86195.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 GAP86195.1 - 0.036 13.5 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein T2SE PF00437.15 GAP86195.1 - 0.04 12.8 0.0 0.067 12.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 GAP86195.1 - 0.04 14.2 0.0 0.06 13.6 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 GAP86195.1 - 0.048 13.3 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase tRNA_lig_kinase PF08303.6 GAP86195.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 tRNA ligase kinase domain SRP54 PF00448.17 GAP86195.1 - 0.14 11.6 0.0 0.75 9.2 0.0 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.13 GAP86195.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 GAP86195.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Peptidase_M49 PF03571.10 GAP86196.1 - 1.6e-223 742.8 0.0 1.8e-223 742.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Ribosomal_L6e PF01159.14 GAP86197.1 - 5.8e-39 132.6 0.4 1e-38 131.8 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e Proteasom_Rpn13 PF04683.8 GAP86198.1 - 2.9e-26 91.3 0.0 4.5e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor DMP1 PF07263.6 GAP86198.1 - 0.51 8.9 8.6 0.68 8.5 5.9 1.1 1 0 0 1 1 1 0 Dentin matrix protein 1 (DMP1) ORC3_N PF07034.6 GAP86200.1 - 3.4e-43 147.8 0.4 9.5e-43 146.4 0.3 1.7 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Ribosomal_L10 PF00466.15 GAP86201.1 - 6e-22 77.4 0.1 1.4e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 GAP86201.1 - 9.3e-13 48.3 2.3 9.3e-13 48.3 1.6 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein PPR_2 PF13041.1 GAP86201.1 - 1.5e-11 44.0 0.0 0.007 16.3 0.0 5.1 5 0 0 5 5 5 3 PPR repeat family PPR_3 PF13812.1 GAP86201.1 - 8.3e-05 22.5 0.8 1 9.7 0.0 6.0 6 0 0 6 6 6 1 Pentatricopeptide repeat domain PPR PF01535.15 GAP86201.1 - 0.00023 20.9 0.1 1 9.4 0.0 4.6 3 0 0 3 3 3 1 PPR repeat VirE_N PF08800.5 GAP86201.1 - 0.14 11.8 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 VirE N-terminal domain MutS_V PF00488.16 GAP86202.1 - 6.5e-73 244.9 0.0 1e-71 241.0 0.0 2.3 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 GAP86202.1 - 3.2e-38 131.5 1.5 4.9e-38 130.9 1.1 1.3 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 GAP86202.1 - 5.8e-21 74.6 0.0 1.4e-20 73.3 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 GAP86202.1 - 1.6e-08 34.6 0.0 4.4e-08 33.2 0.0 1.7 1 1 0 1 1 1 1 MutS domain II AAA_29 PF13555.1 GAP86202.1 - 0.039 13.4 0.0 0.086 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MutS_IV PF05190.13 GAP86202.1 - 0.061 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 MutS family domain IV Glyco_hydro_38 PF01074.17 GAP86204.1 - 2.5e-92 309.0 0.7 4.8e-92 308.0 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 GAP86204.1 - 8.7e-70 235.7 0.0 2.3e-69 234.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 GAP86204.1 - 5.4e-25 87.4 0.0 1.1e-24 86.3 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain CAP_GLY PF01302.20 GAP86205.1 - 7.4e-17 60.8 0.9 1.7e-16 59.6 0.6 1.6 1 0 0 1 1 1 1 CAP-Gly domain Med4 PF10018.4 GAP86205.1 - 0.00037 19.9 13.9 0.033 13.5 1.8 2.9 2 0 0 2 2 2 2 Vitamin-D-receptor interacting Mediator subunit 4 NPV_P10 PF05531.7 GAP86205.1 - 0.031 14.5 0.8 0.031 14.5 0.6 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.6 GAP86205.1 - 0.043 12.4 27.1 0.26 9.8 5.4 3.3 2 1 0 3 3 3 0 Spc7 kinetochore protein AAA_13 PF13166.1 GAP86205.1 - 0.43 8.9 19.5 0.062 11.7 8.1 2.1 1 1 1 2 2 2 0 AAA domain FUSC PF04632.7 GAP86205.1 - 0.47 8.8 11.1 1 7.6 7.7 1.6 1 0 0 1 1 1 0 Fusaric acid resistance protein family Laminin_II PF06009.7 GAP86205.1 - 0.47 10.2 9.9 0.51 10.0 0.9 3.0 2 1 1 3 3 3 0 Laminin Domain II FliD_N PF02465.13 GAP86205.1 - 1.1 9.6 7.6 11 6.5 0.2 2.7 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF3584 PF12128.3 GAP86205.1 - 1.5 6.0 29.8 2.8 5.1 20.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) zf-CCHC_4 PF14392.1 GAP86205.1 - 1.8 8.3 3.3 11 5.7 0.1 2.3 2 0 0 2 2 2 0 Zinc knuckle Baculo_PEP_C PF04513.7 GAP86205.1 - 2.7 7.7 5.2 2.5 7.9 0.9 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 GAP86205.1 - 4.7 6.2 10.4 7.5 5.6 3.5 2.7 2 1 1 3 3 3 0 Reovirus sigma C capsid protein PilJ PF13675.1 GAP86205.1 - 6.6 7.0 17.9 0.11 12.8 2.4 3.6 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Fib_alpha PF08702.5 GAP86205.1 - 6.9 6.7 19.7 0.31 11.1 0.7 3.6 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Tup_N PF08581.5 GAP86205.1 - 7.4 6.8 25.4 0.94 9.7 4.4 4.2 4 1 0 4 4 4 0 Tup N-terminal Nop14 PF04147.7 GAP86207.1 - 1.4e-237 790.7 19.7 1.6e-237 790.5 13.7 1.0 1 0 0 1 1 1 1 Nop14-like family bZIP_1 PF00170.16 GAP86208.1 - 0.0096 15.8 6.7 0.02 14.8 4.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAP86208.1 - 0.026 14.3 8.6 0.026 14.3 5.9 2.3 2 1 0 2 2 2 0 Basic region leucine zipper DnaJ PF00226.26 GAP86209.1 - 9.8e-25 86.0 1.5 1.7e-24 85.3 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 GAP86209.1 - 5.9e-21 74.1 0.1 8.8e-17 60.7 0.0 2.8 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 GAP86209.1 - 3.8e-13 49.2 18.3 3.8e-13 49.2 12.7 1.7 2 0 0 2 2 2 1 DnaJ central domain HypA PF01155.14 GAP86209.1 - 0.0034 17.0 9.1 0.15 11.7 1.3 2.4 1 1 1 2 2 2 2 Hydrogenase expression/synthesis hypA family DUF2614 PF11023.3 GAP86209.1 - 0.55 10.0 5.7 4.8 6.9 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) zinc-ribbons_6 PF07191.7 GAP86209.1 - 0.6 9.9 5.6 6.6 6.5 0.7 2.4 2 0 0 2 2 2 0 zinc-ribbons WD40 PF00400.27 GAP86210.1 - 5.9e-06 25.9 0.8 0.11 12.4 0.1 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat CPSF_A PF03178.10 GAP86210.1 - 0.0055 15.8 0.0 0.012 14.7 0.0 1.4 1 1 0 1 1 1 1 CPSF A subunit region Pkinase PF00069.20 GAP86211.1 - 1.3e-38 132.7 0.0 1.2e-21 77.0 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAP86211.1 - 1.2e-16 60.6 0.0 2.9e-07 29.8 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 GAP86211.1 - 9.7e-07 28.7 0.0 1.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 GAP86211.1 - 0.0021 17.0 0.0 0.63 8.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like DUF4187 PF13821.1 GAP86212.1 - 1.7e-17 62.7 4.1 4.5e-17 61.3 2.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 GAP86212.1 - 4.8e-10 39.0 0.8 8.2e-10 38.3 0.5 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 GAP86212.1 - 0.00042 20.1 0.9 0.0019 17.9 0.6 2.2 1 0 0 1 1 1 1 DExH-box splicing factor binding site DNA_pol_B_thumb PF14791.1 GAP86212.1 - 0.036 13.7 1.4 0.13 12.0 0.9 2.0 1 0 0 1 1 1 0 DNA polymerase beta thumb dCMP_cyt_deam_1 PF00383.17 GAP86213.1 - 4.4e-06 26.2 0.0 4.5e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region UPF0515 PF15135.1 GAP86213.1 - 0.0032 16.6 0.3 0.0049 15.9 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein UPF0515 DUF1556 PF07590.6 GAP86213.1 - 0.071 13.3 1.1 0.11 12.6 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1556) Abhydrolase_6 PF12697.2 GAP86214.1 - 1.1e-18 68.0 3.7 1.5e-18 67.5 2.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP86214.1 - 5e-12 45.8 0.0 6.4e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP86214.1 - 2.6e-07 30.4 0.0 4.7e-07 29.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family zf-HC5HC2H_2 PF13832.1 GAP86215.1 - 1.2e-17 63.8 2.1 1.2e-17 63.8 1.5 4.1 4 1 0 4 4 4 2 PHD-zinc-finger like domain BAH PF01426.13 GAP86215.1 - 1.2e-16 60.5 0.6 2.5e-16 59.4 0.1 1.8 2 0 0 2 2 2 1 BAH domain PHD PF00628.24 GAP86215.1 - 8.1e-15 54.2 57.1 3.4e-08 33.0 8.3 6.0 6 0 0 6 6 6 3 PHD-finger zf-HC5HC2H PF13771.1 GAP86215.1 - 1.3e-14 54.1 4.3 1.3e-14 54.1 3.0 5.1 4 1 0 4 4 4 1 PHD-like zinc-binding domain PHD_2 PF13831.1 GAP86215.1 - 5.8e-09 35.1 6.9 5.8e-09 35.1 4.8 5.3 6 0 0 6 6 6 2 PHD-finger Prok-RING_1 PF14446.1 GAP86215.1 - 4.1e-05 23.2 38.4 0.037 13.7 3.7 4.3 3 0 0 3 3 3 3 Prokaryotic RING finger family 1 TrkA_C PF02080.16 GAP86215.1 - 0.34 10.5 0.0 0.74 9.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-C domain DEAD PF00270.24 GAP86216.1 - 8.7e-18 64.3 0.0 3.5e-17 62.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP86216.1 - 4.9e-08 32.7 0.0 2.3e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 GAP86216.1 - 5.6e-05 23.2 0.0 0.00019 21.5 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain ResIII PF04851.10 GAP86216.1 - 0.0045 16.8 0.0 0.026 14.3 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit COesterase PF00135.23 GAP86217.1 - 1.7e-69 234.9 0.0 1.8e-69 234.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAP86217.1 - 1.4e-07 31.3 2.6 3.4e-07 30.0 1.8 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAP86217.1 - 0.024 13.8 0.1 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAP86217.1 - 0.032 13.9 0.8 0.093 12.4 0.4 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Maf_N PF08383.6 GAP86217.1 - 8.6 6.0 6.3 4.8 6.8 0.0 3.0 3 0 0 3 3 3 0 Maf N-terminal region Abhydrolase_5 PF12695.2 GAP86218.1 - 9.1e-05 22.2 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP86218.1 - 0.00019 21.4 0.0 0.00038 20.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP86218.1 - 0.00023 20.7 0.0 0.00031 20.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 GAP86218.1 - 0.069 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase SNARE_assoc PF09335.6 GAP86220.1 - 1e-14 54.8 6.7 1e-14 54.8 4.6 2.5 2 1 1 3 3 3 1 SNARE associated Golgi protein Neisseria_TspB PF05616.8 GAP86220.1 - 1.1 7.5 5.3 2.6 6.3 3.9 1.4 2 0 0 2 2 2 0 Neisseria meningitidis TspB protein HAMP PF00672.20 GAP86220.1 - 1.4 9.1 0.0 1.4 9.1 0.0 3.2 3 0 0 3 3 3 0 HAMP domain Beta-lactamase PF00144.19 GAP86221.1 - 4.8e-61 206.5 0.0 5.9e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase G-patch PF01585.18 GAP86222.1 - 0.00014 21.5 0.0 0.00047 19.8 0.1 1.8 2 0 0 2 2 2 1 G-patch domain MFS_1 PF07690.11 GAP86223.1 - 5.9e-44 150.2 33.9 6.2e-43 146.8 12.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 GAP86224.1 - 2.5e-05 24.1 10.1 5e-05 23.1 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAP30_Sin3_bdg PF13867.1 GAP86225.1 - 1e-12 47.6 0.6 3.4e-11 42.8 0.1 2.5 2 0 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 DnaJ PF00226.26 GAP86226.1 - 6e-24 83.5 2.2 1e-23 82.7 1.5 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 GAP86226.1 - 1.4e-21 76.1 0.1 3.7e-21 74.8 0.1 1.8 1 0 0 1 1 1 1 DnaJ C terminal domain Axin_b-cat_bind PF08833.5 GAP86226.1 - 0.024 14.3 1.0 0.1 12.2 0.0 2.4 2 0 0 2 2 2 0 Axin beta-catenin binding domain NtA PF03146.10 GAP86226.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Agrin NtA domain BRO1 PF03097.13 GAP86227.1 - 3.1e-128 427.7 0.3 3.1e-128 427.7 0.2 2.2 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 GAP86227.1 - 2.2e-93 312.4 20.3 4.6e-93 311.4 14.1 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Gp58 PF07902.6 GAP86227.1 - 0.0015 16.8 3.7 0.0031 15.8 2.6 1.5 1 0 0 1 1 1 1 gp58-like protein DUF4407 PF14362.1 GAP86227.1 - 0.87 8.4 18.9 0.072 12.0 5.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.6 GAP86227.1 - 8.9 6.7 13.3 4.6 7.7 1.5 3.7 2 1 0 3 3 3 0 Syntaxin 6, N-terminal Avl9 PF09794.4 GAP86228.1 - 6.4e-144 479.1 0.0 8.2e-144 478.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 GAP86228.1 - 6.9e-07 28.9 0.0 0.00048 19.8 0.0 2.3 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 GAP86228.1 - 1.3e-05 24.6 2.3 0.00023 20.5 0.1 3.3 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Cullin PF00888.17 GAP86229.1 - 8.5e-204 678.4 12.2 1.2e-203 677.9 8.5 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 GAP86229.1 - 4e-25 87.4 3.6 4e-25 87.4 2.5 3.0 3 0 0 3 3 3 1 Cullin protein neddylation domain CTD_bind PF04818.8 GAP86229.1 - 0.25 11.6 3.2 0.72 10.1 0.0 3.4 4 0 0 4 4 4 0 RNA polymerase II-binding domain. DUF588 PF04535.7 GAP86230.1 - 0.0014 18.2 0.1 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF588) DUF2569 PF10754.4 GAP86230.1 - 0.021 15.0 0.7 0.021 15.0 0.5 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) Mit_KHE1 PF10173.4 GAP86231.1 - 4.4e-65 219.0 0.7 6.6e-65 218.4 0.5 1.3 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Atg14 PF10186.4 GAP86232.1 - 0.2 10.5 3.9 0.3 9.9 2.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 NOA36 PF06524.7 GAP86232.1 - 5.5 6.1 16.9 2 7.6 1.5 2.1 2 0 0 2 2 2 0 NOA36 protein Raftlin PF15250.1 GAP86232.1 - 9.2 4.6 8.9 0.86 8.0 2.7 1.7 2 0 0 2 2 2 0 Raftlin Methyltransf_31 PF13847.1 GAP86238.1 - 7.2e-09 35.3 0.0 1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP86238.1 - 5.2e-08 33.4 0.0 7e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP86238.1 - 3.3e-07 30.6 0.0 4.6e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAP86238.1 - 4e-07 29.5 0.0 5.5e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 GAP86238.1 - 6.6e-07 29.7 0.0 8.9e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP86238.1 - 7.3e-07 29.2 0.0 1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP86238.1 - 1.6e-06 27.3 0.0 1.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 GAP86238.1 - 1.8e-05 24.5 0.0 2.5e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP86238.1 - 9.4e-05 22.8 0.0 0.00014 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 GAP86238.1 - 0.02 14.2 0.0 0.027 13.8 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PrmA PF06325.8 GAP86238.1 - 0.055 12.5 0.0 0.062 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.6 GAP86238.1 - 0.11 11.8 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) 2_5_RNA_ligase2 PF13563.1 GAP86240.1 - 3.5e-29 101.4 0.0 1.5e-28 99.3 0.0 2.1 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily PAP_central PF04928.12 GAP86240.1 - 1.1e-22 80.0 0.0 2e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain Exo_endo_phos PF03372.18 GAP86240.1 - 1.5e-15 57.8 0.2 4e-15 56.4 0.1 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DUF504 PF04457.7 GAP86240.1 - 1e-11 44.7 0.0 2.3e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF504) NTP_transf_2 PF01909.18 GAP86240.1 - 0.0051 17.1 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_RNA-bind PF04926.10 GAP86240.1 - 0.0081 15.6 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain Nrap PF03813.9 GAP86240.1 - 0.18 9.3 0.0 0.27 8.7 0.0 1.1 1 0 0 1 1 1 0 Nrap protein MCM PF00493.18 GAP86241.1 - 3.8e-128 426.9 0.2 5.2e-128 426.5 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 GAP86241.1 - 1.7e-11 44.6 0.0 1.2e-10 41.9 0.0 2.4 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 GAP86241.1 - 2.5e-07 30.0 0.0 3.1e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 GAP86241.1 - 0.0016 18.0 0.1 0.0068 16.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 GAP86241.1 - 0.0092 15.4 0.0 0.024 14.1 0.0 1.6 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF3801 PF12687.2 GAP86241.1 - 2.7 7.5 7.9 9.8 5.6 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3801) adh_short PF00106.20 GAP86243.1 - 9e-24 84.2 1.8 1.2e-23 83.8 1.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP86243.1 - 6.9e-14 51.9 0.6 9.5e-14 51.4 0.4 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAP86243.1 - 1.3e-10 41.5 0.0 1.8e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAP86243.1 - 5.2e-09 35.8 0.2 7e-09 35.4 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAP86243.1 - 8.5e-07 29.1 0.2 4.3e-06 26.8 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 GAP86243.1 - 0.0087 15.8 0.8 0.15 11.9 0.3 2.3 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DDE_Tnp_Tn3 PF01526.12 GAP86243.1 - 0.17 10.4 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 Tn3 transposase DDE domain DUF566 PF04484.7 GAP86244.1 - 5.8 6.3 6.9 6.3 6.2 4.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) DIE2_ALG10 PF04922.7 GAP86245.1 - 2.5e-71 240.7 11.9 1.4e-63 215.1 6.1 2.3 2 0 0 2 2 2 2 DIE2/ALG10 family Clr5 PF14420.1 GAP86246.1 - 6.1e-18 64.4 1.3 1.6e-17 63.1 0.4 2.0 2 0 0 2 2 2 1 Clr5 domain DHO_dh PF01180.16 GAP86247.1 - 6e-09 35.2 0.0 8.7e-09 34.7 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase SR-25 PF10500.4 GAP86247.1 - 0.13 11.7 18.9 0.2 11.1 6.6 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.3 GAP86247.1 - 0.28 11.3 15.2 0.56 10.4 3.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) DUF755 PF05501.6 GAP86247.1 - 0.57 10.2 15.6 2.7 8.0 7.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DHO_dh PF01180.16 GAP86248.1 - 8e-39 133.3 0.5 1.8e-25 89.5 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase PcrB PF01884.12 GAP86248.1 - 0.00024 20.4 1.9 0.38 9.9 0.3 2.3 2 0 0 2 2 2 2 PcrB family FMN_dh PF01070.13 GAP86248.1 - 0.0096 14.7 3.5 0.02 13.7 2.4 1.6 1 1 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 GAP86248.1 - 0.026 13.4 0.9 0.048 12.5 0.6 1.4 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Ank_2 PF12796.2 GAP86249.1 - 5.6e-91 299.0 4.7 1.8e-18 66.6 0.1 7.5 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 GAP86249.1 - 6.8e-89 287.5 25.6 8.6e-08 31.6 0.1 15.3 15 0 0 15 15 15 13 Ankyrin repeat Ank_4 PF13637.1 GAP86249.1 - 2.2e-67 222.3 24.6 3.1e-10 40.2 0.0 11.6 2 2 11 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP86249.1 - 1.5e-54 176.4 9.5 0.00062 19.7 0.0 14.4 14 1 1 15 15 15 11 Ankyrin repeat Ank_5 PF13857.1 GAP86249.1 - 9.5e-49 162.3 10.9 2.7e-07 30.5 0.0 10.9 4 3 7 11 11 11 9 Ankyrin repeats (many copies) NACHT PF05729.7 GAP86249.1 - 1.1e-06 28.3 0.1 2.5e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 GAP86249.1 - 0.00043 20.3 0.7 0.0033 17.4 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain gag-asp_proteas PF13975.1 GAP86249.1 - 0.0059 16.3 16.9 5.2 6.9 0.1 6.8 5 2 2 7 7 7 2 gag-polyprotein putative aspartyl protease RVP PF00077.15 GAP86249.1 - 0.014 15.3 9.2 31 4.5 0.0 6.0 3 2 1 4 4 4 0 Retroviral aspartyl protease RNA_helicase PF00910.17 GAP86249.1 - 0.048 13.8 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Med4 PF10018.4 GAP86250.1 - 6e-34 117.0 16.4 1e-33 116.3 11.1 1.6 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 CAF-1_p150 PF11600.3 GAP86250.1 - 5.5e-05 22.6 3.4 9e-05 21.9 2.3 1.3 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal EMP70 PF02990.11 GAP86251.1 - 7e-192 638.5 1.9 9e-192 638.1 1.3 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Sas10_Utp3 PF04000.10 GAP86252.1 - 5.9e-15 55.2 0.5 1.1e-14 54.3 0.4 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family DUF2457 PF10446.4 GAP86252.1 - 2.7e-05 23.1 8.3 2.7e-05 23.1 5.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) CobT PF06213.7 GAP86252.1 - 9e-05 21.7 11.5 0.00015 21.0 8.0 1.3 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT CDC45 PF02724.9 GAP86252.1 - 0.00096 17.3 6.3 0.0016 16.5 4.4 1.3 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.7 GAP86252.1 - 0.0064 14.4 9.8 0.0096 13.9 6.8 1.2 1 0 0 1 1 1 1 Nop14-like family Sporozoite_P67 PF05642.6 GAP86252.1 - 0.0077 14.1 3.2 0.011 13.6 2.2 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Daxx PF03344.10 GAP86252.1 - 0.057 11.8 10.1 0.072 11.5 7.0 1.1 1 0 0 1 1 1 0 Daxx Family NOA36 PF06524.7 GAP86252.1 - 0.2 10.8 14.9 0.37 10.0 10.3 1.4 1 0 0 1 1 1 0 NOA36 protein Mpp10 PF04006.7 GAP86252.1 - 0.23 9.7 13.3 0.4 8.9 9.2 1.3 1 0 0 1 1 1 0 Mpp10 protein Sigma70_ner PF04546.8 GAP86252.1 - 0.28 10.7 12.4 0.53 9.8 8.6 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region CDV3 PF15359.1 GAP86252.1 - 0.97 9.5 9.7 2.8 8.0 6.7 1.8 1 1 0 1 1 1 0 Carnitine deficiency-associated protein 3 Nucleoplasmin PF03066.10 GAP86252.1 - 2.2 7.7 16.2 3.5 7.1 11.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin RNA_pol_3_Rpc31 PF11705.3 GAP86252.1 - 4.6 7.1 16.8 10 5.9 11.6 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.5 GAP86252.1 - 4.7 7.4 19.5 11 6.2 13.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.1 GAP86252.1 - 6.7 6.3 6.8 15 5.1 4.7 1.6 1 0 0 1 1 1 0 FAM176 family Dicty_REP PF05086.7 GAP86252.1 - 7.1 4.2 6.1 9 3.9 4.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nop53 PF07767.6 GAP86252.1 - 8.5 5.2 15.0 0.094 11.6 4.3 1.9 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Pyr_redox_3 PF13738.1 GAP86253.1 - 8.3e-18 65.1 0.3 1.7e-17 64.1 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAP86253.1 - 1.3e-12 46.7 0.0 4.3e-12 45.0 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 GAP86253.1 - 6.1e-12 45.8 0.0 4.2e-10 39.8 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAP86253.1 - 3.9e-08 32.6 0.1 2.1e-06 26.9 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 GAP86253.1 - 1.2e-06 27.6 0.6 1.6e-06 27.3 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAP86253.1 - 1.7e-06 27.9 0.8 1.1e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 GAP86253.1 - 7.1e-06 26.1 0.4 0.003 17.6 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 GAP86253.1 - 2.8e-05 24.4 4.4 0.019 15.3 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAP86253.1 - 0.001 18.8 1.8 0.03 14.0 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding 3HCDH_N PF02737.13 GAP86253.1 - 0.0018 17.9 0.3 0.0033 17.0 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 GAP86253.1 - 0.015 14.1 0.9 0.015 14.1 0.6 1.7 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.2 GAP86253.1 - 0.017 14.2 0.0 0.031 13.3 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 GAP86253.1 - 0.022 14.9 0.0 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.9 GAP86253.1 - 0.029 12.8 2.9 0.083 11.3 0.3 2.4 3 0 0 3 3 3 0 HI0933-like protein 2-Hacid_dh_C PF02826.14 GAP86253.1 - 0.03 13.4 0.1 3.4 6.7 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 GAP86253.1 - 0.035 13.9 0.3 0.91 9.3 0.0 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Thi4 PF01946.12 GAP86253.1 - 0.14 11.2 3.2 0.93 8.5 0.2 2.2 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.17 GAP86253.1 - 0.21 10.3 4.1 0.067 12.0 0.6 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A WD40 PF00400.27 GAP86254.1 - 4.6e-80 260.9 62.9 3.2e-12 45.8 0.4 13.2 12 0 0 12 12 12 9 WD domain, G-beta repeat HET PF06985.6 GAP86254.1 - 3.1e-26 92.2 0.7 5.5e-26 91.3 0.5 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Nucleoporin_N PF08801.6 GAP86254.1 - 1e-12 47.5 26.4 0.16 10.7 2.8 8.3 2 1 3 6 6 6 5 Nup133 N terminal like NACHT PF05729.7 GAP86254.1 - 2.5e-07 30.5 0.1 4.5e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.3 GAP86254.1 - 1.7e-05 23.1 17.1 0.27 9.3 0.0 6.9 3 2 2 5 5 5 3 Nucleoporin Nup120/160 AAA_16 PF13191.1 GAP86254.1 - 0.00025 21.0 0.0 0.00081 19.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Cytochrom_D1 PF02239.11 GAP86254.1 - 0.00089 17.6 0.6 0.066 11.4 0.0 3.0 3 0 0 3 3 3 1 Cytochrome D1 heme domain PD40 PF07676.7 GAP86254.1 - 0.001 18.6 12.2 0.51 10.0 0.1 7.2 9 0 0 9 9 9 1 WD40-like Beta Propeller Repeat RicinB_lectin_2 PF14200.1 GAP86254.1 - 0.0064 16.8 3.2 1.7 9.0 0.1 4.1 2 2 2 4 4 4 1 Ricin-type beta-trefoil lectin domain-like AAA_22 PF13401.1 GAP86254.1 - 0.018 15.1 0.0 0.054 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAP86254.1 - 0.062 14.1 0.0 0.31 11.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.15 GAP86254.1 - 0.064 12.9 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase HTH_20 PF12840.2 GAP86254.1 - 0.069 12.9 0.1 0.4 10.5 0.0 2.3 3 0 0 3 3 2 0 Helix-turn-helix domain AAA_19 PF13245.1 GAP86254.1 - 0.13 12.0 0.0 0.45 10.3 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain NB-ARC PF00931.17 GAP86254.1 - 0.17 10.7 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain CHORD PF04968.7 GAP86256.1 - 1.6e-50 169.1 17.6 4.2e-25 87.7 3.0 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.11 GAP86256.1 - 3e-12 46.8 0.0 5e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 CS domain HpcH_HpaI PF03328.9 GAP86257.1 - 1.6e-33 115.4 0.0 1.9e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.1 GAP86257.1 - 0.085 12.0 1.3 5.6 6.1 0.0 2.7 2 2 1 3 3 3 0 Phosphoenolpyruvate phosphomutase Fungal_trans PF04082.13 GAP86258.1 - 1.8e-10 40.1 0.2 2.6e-10 39.5 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP86258.1 - 6.3e-09 35.6 9.1 6.3e-09 35.6 6.3 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 GAP86259.1 - 5.3e-16 58.6 0.1 9.5e-16 57.7 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAP86259.1 - 4.9e-10 38.8 0.1 0.00071 18.5 0.2 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAP86259.1 - 7.3e-07 29.5 0.0 1.6e-05 25.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP86259.1 - 0.011 15.6 0.1 0.027 14.4 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 GAP86259.1 - 0.031 12.9 0.2 1.9 7.0 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.11 GAP86259.1 - 0.055 12.9 0.1 0.084 12.3 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Mg_trans_NIPA PF05653.9 GAP86260.1 - 5.3e-88 294.8 25.1 7.5e-88 294.3 17.4 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 GAP86260.1 - 2.9e-06 27.4 7.0 2.9e-06 27.4 4.9 2.9 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 GAP86260.1 - 2.4e-05 24.3 8.6 2.4e-05 24.3 6.0 2.8 2 1 0 2 2 2 1 EamA-like transporter family Nucleoplasmin PF03066.10 GAP86260.1 - 1.2 8.5 7.6 2.4 7.6 5.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin Acetyltransf_2 PF00797.12 GAP86262.1 - 6.9e-29 101.1 0.0 1e-27 97.2 0.0 2.2 2 0 0 2 2 2 1 N-acetyltransferase TPR_11 PF13414.1 GAP86263.1 - 1.1e-17 63.4 6.7 5.9e-15 54.6 2.9 2.3 1 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 GAP86263.1 - 1.1e-10 40.5 7.0 0.0043 16.8 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 GAP86263.1 - 3.8e-10 38.9 4.3 0.004 16.7 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAP86263.1 - 2.3e-09 37.6 22.0 7.8e-08 32.7 3.9 2.7 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAP86263.1 - 1.5e-07 31.0 1.2 0.0074 16.4 0.3 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAP86263.1 - 4.1e-07 30.0 6.5 0.006 17.1 2.8 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAP86263.1 - 0.0002 21.2 13.6 0.0013 18.6 2.6 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAP86263.1 - 0.00035 20.8 3.7 0.00035 20.8 2.6 2.3 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAP86263.1 - 0.00092 18.8 1.0 1.9 8.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat XPC-binding PF09280.6 GAP86263.1 - 0.002 17.5 3.6 0.0032 16.9 2.0 1.7 2 0 0 2 2 2 1 XPC-binding domain BTAD PF03704.12 GAP86263.1 - 0.0083 16.4 2.2 3.2 8.0 0.7 2.4 1 1 1 2 2 2 2 Bacterial transcriptional activator domain SR-25 PF10500.4 GAP86263.1 - 0.059 12.8 3.7 0.096 12.1 2.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TPR_9 PF13371.1 GAP86263.1 - 0.098 12.5 5.0 0.12 12.2 1.4 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAP86263.1 - 0.1 12.4 1.4 9.9 6.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 GAP86263.1 - 0.12 12.3 3.6 9.4 6.3 2.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAP86263.1 - 0.12 12.8 7.1 6.4 7.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ABC_tran PF00005.22 GAP86264.1 - 1.2e-31 109.8 0.0 4.2e-31 108.0 0.0 1.9 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 GAP86264.1 - 2.8e-09 36.8 3.7 6.1e-09 35.6 2.6 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 GAP86264.1 - 0.00015 21.1 0.0 0.0013 18.0 0.0 1.9 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAP86264.1 - 0.0004 20.4 0.0 0.013 15.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain PAM2 PF07145.10 GAP86264.1 - 0.00056 19.2 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 Ataxin-2 C-terminal region AAA_29 PF13555.1 GAP86264.1 - 0.022 14.3 0.1 0.059 12.9 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 GAP86264.1 - 0.026 13.9 0.1 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 GAP86264.1 - 0.06 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 APS_kinase PF01583.15 GAP86264.1 - 0.086 12.4 0.2 0.27 10.8 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_23 PF13476.1 GAP86264.1 - 0.29 11.4 1.6 0.3 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain HD PF01966.17 GAP86265.1 - 0.0034 17.3 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 HD domain PAN_4 PF14295.1 GAP86266.1 - 6e-07 29.0 0.3 2.7e-06 26.9 0.2 2.2 1 1 0 1 1 1 1 PAN domain PAN_1 PF00024.21 GAP86266.1 - 0.0029 17.3 0.0 0.0057 16.3 0.0 1.5 1 0 0 1 1 1 1 PAN domain Mucin PF01456.12 GAP86266.1 - 1.3 8.7 16.4 0.96 9.2 10.0 1.7 1 1 1 2 2 2 0 Mucin-like glycoprotein RhoGAP PF00620.22 GAP86267.1 - 5.5e-17 61.7 0.0 1.5e-16 60.4 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain Defensin_propep PF00879.13 GAP86268.1 - 0.37 10.7 1.2 1.5 8.8 0.1 2.3 2 0 0 2 2 2 0 Defensin propeptide CagX PF03524.10 GAP86269.1 - 3.1 7.0 6.0 4.8 6.4 4.1 1.3 1 0 0 1 1 1 0 Conjugal transfer protein DUF3513 PF12026.3 GAP86269.1 - 3.2 7.2 11.4 4.1 6.8 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) PAT1 PF09770.4 GAP86269.1 - 9.7 4.2 18.8 11 4.1 13.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-RING_2 PF13639.1 GAP86271.1 - 4.9e-09 35.8 8.2 1.1e-08 34.7 5.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAP86271.1 - 1.7e-07 31.2 2.5 4e-07 30.0 1.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 GAP86271.1 - 6.1e-06 26.1 9.0 2e-05 24.4 6.2 1.9 1 1 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 GAP86271.1 - 0.0002 21.0 2.4 0.00048 19.8 1.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger C1_1 PF00130.17 GAP86271.1 - 0.00081 19.0 3.8 0.00081 19.0 2.7 1.7 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RINGv PF12906.2 GAP86271.1 - 0.0014 18.6 8.8 0.0039 17.2 6.1 1.9 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4 PF00097.20 GAP86271.1 - 0.002 17.7 10.6 0.0044 16.6 7.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAP86271.1 - 0.0035 16.9 5.6 0.008 15.8 3.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAP86271.1 - 0.012 15.5 9.3 0.032 14.2 6.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_RING PF05883.6 GAP86271.1 - 0.1 12.4 2.1 0.23 11.2 1.4 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING-like PF08746.6 GAP86271.1 - 0.28 11.2 8.3 0.59 10.1 5.7 1.6 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 GAP86271.1 - 3.4 7.4 7.8 6.8 6.4 5.4 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 GAP86271.1 - 5.7 6.6 7.7 55 3.4 5.4 2.3 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.1 GAP86271.1 - 7.4 6.3 6.6 28 4.5 4.6 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Sigma70_r4 PF04545.11 GAP86272.1 - 0.08 12.2 0.1 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 DUF4210 PF13915.1 GAP86273.1 - 5.4e-27 93.8 0.4 3.6e-26 91.2 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 GAP86273.1 - 6.8e-22 77.1 0.4 1.4e-21 76.0 0.3 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis rRNA_processing PF08524.6 GAP86274.1 - 1.3e-06 28.2 12.9 0.0031 17.3 0.1 2.3 2 0 0 2 2 2 2 rRNA processing CDC45 PF02724.9 GAP86274.1 - 0.74 7.7 8.8 0.97 7.3 6.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Kelch_5 PF13854.1 GAP86275.1 - 1e-12 47.6 12.0 4.7e-08 32.8 0.2 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 GAP86275.1 - 0.0027 17.3 1.8 9.1 6.2 0.0 5.4 6 0 0 6 6 6 1 Kelch motif Kelch_3 PF13415.1 GAP86275.1 - 0.023 14.8 13.3 4.4 7.6 0.5 6.7 6 0 0 6 6 6 0 Galactose oxidase, central domain RhoGAP PF00620.22 GAP86276.1 - 3.5e-47 159.8 3.0 2.5e-46 157.0 0.0 2.8 3 0 0 3 3 3 1 RhoGAP domain LIM PF00412.17 GAP86276.1 - 4.4e-14 52.2 19.0 4.5e-09 36.2 1.6 2.4 2 0 0 2 2 2 2 LIM domain Zn-ribbon_8 PF09723.5 GAP86276.1 - 1.6 8.7 20.1 0.22 11.4 1.0 4.0 4 0 0 4 4 4 0 Zinc ribbon domain CCDC155 PF14662.1 GAP86276.1 - 2.3 7.7 21.5 1.3 8.5 5.5 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Cytochrom_CIII PF02085.11 GAP86276.1 - 4.2 7.5 10.3 12 6.0 7.2 1.8 1 0 0 1 1 1 0 Class III cytochrome C family Acetyltransf_10 PF13673.1 GAP86277.1 - 6.9e-10 39.0 0.5 1.5e-06 28.3 0.1 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAP86277.1 - 3.6e-07 30.2 0.0 9.5e-07 28.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAP86277.1 - 2.2e-06 27.5 0.0 3.7e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 GAP86277.1 - 2.9e-05 23.8 0.1 7.9e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 GAP86277.1 - 0.00098 18.8 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 GAP86277.1 - 0.0025 17.6 0.0 0.0052 16.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 GAP86277.1 - 0.036 13.6 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAP86277.1 - 0.081 12.7 0.1 0.6 9.9 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PPR_2 PF13041.1 GAP86278.1 - 1.5e-14 53.7 5.2 4.1e-05 23.4 0.0 6.9 5 1 4 9 9 9 4 PPR repeat family PPR PF01535.15 GAP86278.1 - 4.6e-13 48.2 0.8 0.0035 17.2 0.0 6.8 7 0 0 7 7 7 3 PPR repeat PPR_3 PF13812.1 GAP86278.1 - 2.2e-09 36.8 2.6 0.35 11.2 0.0 8.5 10 0 0 10 10 10 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 GAP86278.1 - 5.8e-06 25.6 0.2 0.81 9.2 0.0 4.4 4 0 0 4 4 4 2 PPR repeat TPR_6 PF13174.1 GAP86278.1 - 0.038 14.4 3.8 14 6.4 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAP86278.1 - 0.057 13.3 3.1 31 4.7 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAP86278.1 - 3 7.6 6.2 63 3.4 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat SIMPL PF04402.9 GAP86279.1 - 0.0055 16.5 1.9 0.025 14.4 1.4 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF541) HSP70 PF00012.15 GAP86280.1 - 8.1e-267 886.0 16.2 9.3e-267 885.8 11.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAP86280.1 - 8.5e-16 57.4 5.5 1.2e-13 50.3 1.5 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 GAP86280.1 - 0.00024 20.9 5.2 8.4 6.2 3.6 4.6 1 1 0 1 1 1 1 Cell division protein FtsA FGGY_C PF02782.11 GAP86280.1 - 0.0004 20.0 0.1 0.0011 18.6 0.1 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF4363 PF14276.1 GAP86280.1 - 0.29 10.8 3.9 0.57 9.8 2.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Hydantoinase_A PF01968.13 GAP86280.1 - 2.3 7.2 9.8 1.5 7.8 0.0 3.6 3 1 1 4 4 4 0 Hydantoinase/oxoprolinase DUF2415 PF10313.4 GAP86281.1 - 2.4e-15 55.9 0.0 5.1e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 GAP86281.1 - 0.02 14.7 6.6 19 5.3 0.1 5.4 6 0 0 6 6 6 0 WD domain, G-beta repeat DAO PF01266.19 GAP86282.1 - 1.5e-24 86.5 16.7 1.4e-22 80.1 11.6 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAP86282.1 - 0.0021 18.0 1.0 0.008 16.1 0.7 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAP86282.1 - 0.0083 16.2 0.0 1.1 9.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAP86282.1 - 0.083 13.3 0.1 0.18 12.2 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Spc24 PF08286.6 GAP86283.1 - 0.09 12.4 3.8 0.14 11.8 0.1 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF2046 PF09755.4 GAP86283.1 - 0.53 9.1 6.8 0.12 11.2 1.3 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) MFS_1 PF07690.11 GAP86284.1 - 3.8e-32 111.3 32.1 1.8e-27 95.9 7.1 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP86284.1 - 1.8e-07 30.1 8.4 1.8e-07 30.1 5.8 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.2 GAP86284.1 - 0.0025 17.5 3.5 1.9 8.3 0.0 3.9 3 1 0 3 3 3 2 MFS_1 like family MFS_3 PF05977.8 GAP86284.1 - 0.15 10.1 4.4 0.95 7.4 3.0 2.0 1 1 0 1 1 1 0 Transmembrane secretion effector Pkinase PF00069.20 GAP86285.1 - 4.6e-27 94.7 0.0 7.7e-27 94.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP86285.1 - 3.5e-13 49.2 0.0 5.6e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ketoacyl-synt PF00109.21 GAP86286.1 - 5.7e-71 238.9 0.1 1e-70 238.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAP86286.1 - 8.7e-49 166.5 0.0 1.4e-48 165.9 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAP86286.1 - 2.3e-35 121.0 1.8 3.7e-35 120.3 0.2 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 GAP86286.1 - 2.2e-21 76.2 0.0 1.5e-20 73.6 0.0 2.3 2 0 0 2 2 2 1 Polyketide synthase dehydratase PP-binding PF00550.20 GAP86286.1 - 6.5e-21 74.3 5.1 1.4e-10 41.2 0.1 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.15 GAP86286.1 - 2.2e-20 73.8 0.2 8.5e-20 71.9 0.0 2.2 2 1 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.2 GAP86286.1 - 8.5e-06 25.8 1.3 0.0011 18.9 0.1 3.2 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP86286.1 - 3.1e-05 23.7 0.1 0.23 11.2 0.0 2.7 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 GAP86286.1 - 0.00098 18.1 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF2974 PF11187.3 GAP86286.1 - 0.0018 17.6 0.0 0.0043 16.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) HMG_box_5 PF14887.1 GAP86286.1 - 0.27 11.0 0.0 1 9.2 0.0 1.9 2 0 0 2 2 2 0 HMG (high mobility group) box 5 COesterase PF00135.23 GAP86287.1 - 5.6e-79 266.2 0.0 1.7e-78 264.6 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAP86287.1 - 0.001 18.7 3.7 0.001 18.7 2.5 3.1 3 1 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP86287.1 - 0.014 15.1 0.4 0.022 14.4 0.3 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGI PF00342.14 GAP86288.1 - 8.6e-211 700.5 0.0 9.8e-211 700.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Pkinase PF00069.20 GAP86289.1 - 3.8e-71 239.2 0.0 4.8e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP86289.1 - 1.4e-34 119.3 0.0 1.9e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 GAP86289.1 - 4.5e-10 39.8 4.4 1.2e-09 38.5 3.0 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 GAP86289.1 - 0.00042 19.3 0.0 0.00073 18.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAP86289.1 - 0.11 11.4 0.1 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3176 PF11374.3 GAP86290.1 - 4.5e-31 107.0 1.2 4.5e-31 107.0 0.8 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) MHYT PF03707.11 GAP86290.1 - 7.5 6.7 8.4 0.35 11.0 0.6 2.6 2 1 0 2 2 2 0 Bacterial signalling protein N terminal repeat Exo5 PF09810.4 GAP86291.1 - 4.2e-109 364.6 0.0 5.2e-109 364.3 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 GAP86291.1 - 1.8e-07 30.8 0.0 4.7e-07 29.4 0.0 1.7 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily GATA PF00320.22 GAP86291.1 - 1.8 7.9 9.4 0.97 8.8 0.8 2.7 2 0 0 2 2 2 0 GATA zinc finger Glyco_hydro_30 PF02055.11 GAP86292.1 - 2e-19 69.2 0.1 5.2e-14 51.3 0.1 2.5 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 GAP86292.1 - 4.3e-17 62.1 0.2 1.3e-13 50.6 0.0 2.2 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 PfkB PF00294.19 GAP86292.1 - 0.0083 15.2 3.1 0.014 14.5 2.2 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Acyl-CoA_dh_1 PF00441.19 GAP86293.1 - 9.7e-29 100.4 2.3 1.7e-28 99.6 1.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 GAP86293.1 - 6.4e-19 67.2 0.8 1.2e-18 66.2 0.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 GAP86293.1 - 3e-13 50.3 0.0 1.5e-12 48.0 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 GAP86293.1 - 4e-07 30.3 2.3 6.8e-07 29.6 0.4 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Sulfotransfer_3 PF13469.1 GAP86294.1 - 0.0031 18.4 1.2 0.0054 17.6 0.8 1.4 1 0 0 1 1 1 1 Sulfotransferase family DUF4508 PF14969.1 GAP86294.1 - 0.044 13.7 0.0 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) Glyco_hydro_31 PF01055.21 GAP86296.1 - 1e-119 400.2 0.1 1.3e-119 399.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 GAP86296.1 - 0.0002 21.1 1.6 0.0011 18.7 0.0 2.7 3 1 0 3 3 3 1 Galactose mutarotase-like Ish1 PF10281.4 GAP86297.1 - 1.7e-75 248.6 20.8 5.3e-16 58.3 0.0 8.5 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein SAP PF02037.22 GAP86297.1 - 8.8e-10 37.8 0.0 8.8 5.9 0.0 8.3 10 0 0 10 10 10 2 SAP domain Slx4 PF09494.5 GAP86297.1 - 5e-08 32.5 2.9 1.6 8.4 0.0 6.4 7 0 0 7 7 7 2 Slx4 endonuclease HeH PF12949.2 GAP86297.1 - 6.6e-08 31.9 0.1 4.7 6.8 0.0 6.3 7 0 0 7 7 7 3 HeH/LEM domain APC2 PF08672.6 GAP86297.1 - 0.00079 19.6 1.6 14 6.0 0.0 5.6 6 0 0 6 6 6 1 Anaphase promoting complex (APC) subunit 2 LEM PF03020.10 GAP86297.1 - 0.051 13.0 0.0 16 5.0 0.0 4.1 4 0 0 4 4 4 0 LEM domain SAM_2 PF07647.12 GAP86297.1 - 0.14 12.0 1.4 49 3.8 0.0 4.0 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) Mannosyl_trans3 PF11051.3 GAP86298.1 - 0.0076 15.6 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Asp PF00026.18 GAP86299.1 - 1.4e-10 40.9 0.0 2.2e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease VSP PF03302.8 GAP86299.1 - 0.0025 16.5 0.2 0.004 15.8 0.1 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein SKG6 PF08693.5 GAP86299.1 - 0.0039 16.4 0.7 0.0085 15.3 0.5 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rax2 PF12768.2 GAP86299.1 - 0.0075 15.5 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Cortical protein marker for cell polarity NmrA PF05368.8 GAP86301.1 - 4.9e-16 58.6 0.0 6.1e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAP86301.1 - 3.3e-10 40.2 0.0 4.4e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAP86301.1 - 0.00093 18.6 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 GAP86301.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Skp1 PF01466.14 GAP86302.1 - 1.3e-29 102.0 1.7 1.4e-29 101.9 0.5 1.5 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 GAP86302.1 - 1e-08 35.1 0.0 1.6e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain HET PF06985.6 GAP86304.1 - 1.2e-14 54.6 0.8 3.6e-14 53.0 0.2 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) HAD PF12710.2 GAP86306.1 - 1.4e-11 44.9 1.6 3.1e-08 33.9 1.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAP86306.1 - 0.0056 17.1 0.0 1.2 9.4 0.0 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.8 GAP86306.1 - 0.0061 15.8 0.0 0.015 14.5 0.0 1.6 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.7 GAP86306.1 - 0.025 14.1 0.0 0.61 9.6 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase TFIIF_beta PF02270.10 GAP86307.1 - 4.8e-64 216.8 8.0 5.8e-64 216.5 5.5 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Ofd1_CTDD PF10637.4 GAP86307.1 - 0.0095 15.0 1.0 0.018 14.1 0.7 1.4 1 0 0 1 1 1 1 Oxoglutarate and iron-dependent oxygenase degradation C-term CDC37_C PF08564.5 GAP86307.1 - 0.11 12.3 1.9 0.12 12.1 0.1 2.0 2 0 0 2 2 2 0 Cdc37 C terminal domain zf-CCCH PF00642.19 GAP86308.1 - 1.9e-08 33.7 14.2 0.019 14.6 0.3 4.7 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 GAP86308.1 - 0.035 13.5 0.8 0.12 11.8 0.6 1.9 1 0 0 1 1 1 0 Putative zinc-finger domain BBP1_C PF15272.1 GAP86308.1 - 2.9 7.3 7.8 0.12 11.8 0.4 2.2 3 0 0 3 3 3 0 Spindle pole body component BBP1, C-terminal Sel1 PF08238.7 GAP86309.1 - 9.6e-20 70.5 5.7 4e-06 27.2 0.5 3.8 3 0 0 3 3 3 3 Sel1 repeat bZIP_1 PF00170.16 GAP86310.1 - 7.5e-07 29.0 14.9 9.6e-07 28.6 8.0 2.6 1 1 2 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.10 GAP86310.1 - 6e-05 22.7 9.3 6e-05 22.7 6.4 3.0 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.12 GAP86310.1 - 0.00023 21.3 16.6 0.0009 19.4 9.5 2.6 1 1 1 2 2 2 1 bZIP Maf transcription factor DUF342 PF03961.8 GAP86310.1 - 0.98 7.7 8.2 1.5 7.1 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 GAP86310.1 - 1 8.3 11.3 1.7 7.6 7.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.10 GAP86310.1 - 3.1 7.4 12.7 8.3 6.0 8.7 1.7 1 1 0 1 1 1 0 Mnd1 family CBF PF03914.12 GAP86312.1 - 1.1e-44 151.7 1.6 2.1e-44 150.8 0.3 2.1 2 0 0 2 2 2 1 CBF/Mak21 family Mt_ATP-synt_B PF05405.9 GAP86313.1 - 2.2e-52 176.7 5.8 2.8e-52 176.4 4.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Rep_trans PF02486.14 GAP86313.1 - 0.077 12.4 0.6 0.15 11.5 0.4 1.4 1 0 0 1 1 1 0 Replication initiation factor rve_3 PF13683.1 GAP86313.1 - 0.15 11.6 0.2 0.98 8.9 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain HECT_2 PF09814.4 GAP86314.1 - 3.9e-60 203.4 0.0 3e-32 111.7 0.0 2.0 2 0 0 2 2 2 2 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Adipokin_hormo PF06377.6 GAP86314.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Adipokinetic hormone DUF4243 PF14027.1 GAP86315.1 - 1.4e-79 267.9 0.1 1.7e-79 267.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Cornichon PF03311.9 GAP86315.1 - 0.056 13.5 0.0 0.15 12.1 0.0 1.8 1 1 0 1 1 1 0 Cornichon protein Rad17 PF03215.10 GAP86316.1 - 1.7e-55 188.6 0.0 2.8e-55 187.9 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 GAP86316.1 - 0.00084 19.5 0.0 0.0024 18.0 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 GAP86316.1 - 0.0017 18.0 0.0 0.0045 16.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 GAP86316.1 - 0.0049 16.9 0.0 0.03 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 GAP86316.1 - 0.0082 15.7 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAP86316.1 - 0.034 14.1 0.0 0.12 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 GAP86316.1 - 0.048 13.3 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 NACHT domain T2SE PF00437.15 GAP86316.1 - 0.072 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF853 PF05872.7 GAP86316.1 - 0.11 10.8 0.0 0.18 10.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF294 PF03445.8 GAP86316.1 - 0.19 11.3 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 Putative nucleotidyltransferase DUF294 TrwB_AAD_bind PF10412.4 GAP86316.1 - 0.3 9.6 0.3 0.62 8.6 0.2 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Abhydrolase_3 PF07859.8 GAP86319.1 - 4.8e-41 140.6 0.0 6.4e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 GAP86319.1 - 4.6e-07 28.9 0.0 7.3e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 GAP86319.1 - 0.0038 16.9 0.0 0.0051 16.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 GAP86319.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase AXE1 PF05448.7 GAP86319.1 - 0.16 10.4 0.0 1.7 7.0 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF2974 PF11187.3 GAP86319.1 - 0.18 11.1 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) tRNA-synt_2 PF00152.15 GAP86320.1 - 2.3e-79 266.6 0.0 3.4e-79 266.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 GAP86320.1 - 1.3e-22 80.0 0.0 2.1e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 GAP86320.1 - 1.1e-08 34.7 0.0 7.2e-08 32.1 0.0 2.4 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 GAP86320.1 - 0.056 12.6 0.4 6 5.9 0.0 2.5 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) ABC2_membrane PF01061.19 GAP86321.1 - 3.2e-90 300.9 59.3 2.8e-46 157.3 15.8 2.7 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 GAP86321.1 - 2.3e-32 110.7 2.4 1.2e-25 89.0 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 GAP86321.1 - 4.5e-20 72.3 0.0 1.1e-16 61.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 GAP86321.1 - 1.9e-05 23.8 7.7 1.9e-05 23.8 5.3 2.9 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 GAP86321.1 - 3.1e-05 23.9 0.1 9.9e-05 22.3 0.1 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF236 PF03057.9 GAP86321.1 - 0.028 14.3 0.1 0.072 13.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function SMC_N PF02463.14 GAP86321.1 - 0.048 12.8 0.1 0.2 10.8 0.0 1.9 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain Pox_A31 PF05771.6 GAP86321.1 - 0.075 12.8 0.1 0.23 11.2 0.1 1.8 1 0 0 1 1 1 0 Poxvirus A31 protein AAA_25 PF13481.1 GAP86321.1 - 0.077 12.3 0.0 1.7 8.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 GAP86321.1 - 0.096 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain F-box-like PF12937.2 GAP86322.1 - 0.0054 16.4 0.5 0.0054 16.4 0.3 2.4 3 0 0 3 3 3 1 F-box-like F-box-like_2 PF13013.1 GAP86322.1 - 0.07 12.8 0.1 0.19 11.4 0.1 1.7 1 0 0 1 1 1 0 F-box-like domain MFS_1 PF07690.11 GAP86323.1 - 2.2e-35 122.0 26.4 2.2e-35 122.0 18.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP86323.1 - 1.1e-11 43.9 11.9 1.1e-11 43.9 8.2 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 GAP86323.1 - 2.6e-08 32.5 9.1 1.7e-07 29.8 4.2 2.1 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) PUA PF01472.15 GAP86324.1 - 9e-13 47.7 0.1 1.9e-06 27.4 0.0 2.1 2 0 0 2 2 2 2 PUA domain PetG PF02529.10 GAP86325.1 - 0.0032 16.9 1.8 0.0068 15.9 1.3 1.6 1 0 0 1 1 1 1 Cytochrome B6-F complex subunit 5 TPT PF03151.11 GAP86326.1 - 1.6e-26 92.7 12.1 1.6e-26 92.7 8.4 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 GAP86326.1 - 1.2e-06 27.6 23.3 8e-06 24.9 16.2 2.0 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 GAP86326.1 - 0.0053 16.7 36.2 0.011 15.8 5.6 3.1 3 0 0 3 3 3 2 EamA-like transporter family NST1 PF13945.1 GAP86327.1 - 5.9e-50 169.9 3.6 5.9e-50 169.9 2.5 5.7 3 2 2 5 5 5 3 Salt tolerance down-regulator Ras PF00071.17 GAP86328.1 - 7e-49 165.3 0.0 8.2e-49 165.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAP86328.1 - 2e-15 57.3 0.0 2.8e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAP86328.1 - 1.9e-06 27.2 0.0 2.8e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAP86328.1 - 0.0076 15.4 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 GAP86328.1 - 0.021 14.0 0.0 0.033 13.4 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 GAP86328.1 - 0.022 14.2 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.1 GAP86328.1 - 0.071 13.0 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 GAP86328.1 - 0.081 12.8 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase MRP-L28 PF09812.4 GAP86329.1 - 4.5e-08 33.0 0.4 4.5e-08 33.0 0.3 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L28 Methyltransf_16 PF10294.4 GAP86336.1 - 5.8e-12 45.3 0.0 8.3e-07 28.6 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase AMP-binding PF00501.23 GAP86338.1 - 7.8e-84 281.4 0.0 1.1e-83 280.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme CdhD PF03599.11 GAP86338.1 - 0.0043 15.6 0.0 0.0072 14.8 0.0 1.2 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit EF-hand_7 PF13499.1 GAP86339.1 - 3.3e-29 100.8 12.4 2e-13 50.2 0.7 3.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 GAP86339.1 - 2.7e-24 82.5 14.0 3.8e-08 32.0 0.2 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 GAP86339.1 - 1.3e-23 80.7 4.4 7.1e-06 25.4 0.1 5.1 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 GAP86339.1 - 6.7e-17 59.9 14.8 2.5e-05 23.3 0.0 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 GAP86339.1 - 2.6e-14 52.5 13.4 1.7e-05 24.3 0.9 4.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 GAP86339.1 - 3.3e-09 36.4 8.6 0.0039 16.9 0.1 4.0 1 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 GAP86339.1 - 7.3e-05 22.6 0.5 0.022 14.6 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 GAP86339.1 - 0.0012 18.9 2.4 0.37 10.8 0.1 3.0 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 GAP86339.1 - 0.0039 16.8 3.7 0.33 10.6 0.1 4.0 4 0 0 4 4 4 1 EF hand Toprim PF01751.17 GAP86339.1 - 0.011 15.6 0.0 3.9 7.5 0.0 2.3 1 1 1 2 2 2 0 Toprim domain DUF1679 PF07914.6 GAP86339.1 - 0.016 13.8 0.6 1.3 7.5 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1679) EF-hand_2 PF09068.6 GAP86339.1 - 0.02 14.9 0.1 2.9 7.9 0.0 3.1 3 1 1 4 4 4 0 EF hand CDC45 PF02724.9 GAP86340.1 - 3.4e-235 781.8 0.9 5e-234 777.9 0.6 2.9 1 1 0 1 1 1 1 CDC45-like protein Cwf_Cwc_15 PF04889.7 GAP86340.1 - 0.0051 16.5 8.0 0.0051 16.5 5.5 2.2 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Trypan_PARP PF05887.6 GAP86340.1 - 8.1 6.2 22.2 0.033 13.9 3.2 2.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Nop25 PF09805.4 GAP86340.1 - 9.2 6.3 23.4 0.079 13.0 9.5 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Cupin_8 PF13621.1 GAP86341.1 - 4.1e-32 111.6 0.0 5.9e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 GAP86341.1 - 7.7e-08 31.9 0.0 1.9e-05 24.0 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 GAP86341.1 - 0.0071 16.5 0.0 0.033 14.4 0.0 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase Peptidase_C36 PF05415.6 GAP86341.1 - 0.0071 16.2 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Beet necrotic yellow vein furovirus-type papain-like endopeptidase Cupin_2 PF07883.6 GAP86341.1 - 0.015 14.8 0.2 0.064 12.7 0.0 2.1 2 0 0 2 2 2 0 Cupin domain HA2 PF04408.18 GAP86342.1 - 4e-28 97.4 0.1 1.2e-27 95.9 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 GAP86342.1 - 1.2e-27 96.0 0.0 4.1e-27 94.2 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 GAP86342.1 - 1.4e-12 47.2 0.0 3.7e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 GAP86342.1 - 1.4e-11 44.3 0.6 3.1e-11 43.1 0.4 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 GAP86342.1 - 7.8e-06 25.4 0.1 2e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAP86342.1 - 1.2e-05 25.4 0.0 3.4e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 GAP86342.1 - 7e-05 21.8 0.2 0.0002 20.3 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.1 GAP86342.1 - 0.0015 18.1 0.0 0.022 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 GAP86342.1 - 0.026 14.4 0.1 0.17 11.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 GAP86342.1 - 0.034 13.9 0.1 0.099 12.4 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activ_2 PF14532.1 GAP86342.1 - 0.053 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 GAP86342.1 - 0.069 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 GAP86342.1 - 0.087 13.1 0.0 0.66 10.2 0.0 2.5 2 0 0 2 2 2 0 ABC transporter Herpes_ori_bp PF02399.10 GAP86342.1 - 0.3 9.0 0.0 0.48 8.3 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein Pmp3 PF01679.12 GAP86343.1 - 3e-21 74.8 5.1 4.2e-21 74.3 3.5 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SUV3_C PF12513.3 GAP86345.1 - 5.2e-18 64.2 0.1 1.2e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 GAP86345.1 - 3.5e-09 36.3 0.0 7.6e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Alginate_lyase2 PF08787.6 GAP86346.1 - 5.8e-34 117.7 0.0 6.9e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Alginate lyase Synaptobrevin PF00957.16 GAP86348.1 - 8.9e-31 105.3 0.4 1.3e-30 104.8 0.3 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 GAP86348.1 - 4.6e-22 77.3 0.0 1.1e-21 76.1 0.0 1.6 2 0 0 2 2 2 1 Regulated-SNARE-like domain MutL PF13941.1 GAP86349.1 - 0.014 13.7 0.0 0.016 13.6 0.0 1.0 1 0 0 1 1 1 0 MutL protein adh_short PF00106.20 GAP86350.1 - 1.2e-15 57.8 0.3 9.7e-15 54.8 0.0 2.3 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 GAP86350.1 - 1.6e-07 31.1 0.1 6.1e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 GAP86350.1 - 6.4e-05 23.0 0.0 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 GAP86350.1 - 7.6e-05 22.5 0.0 0.0029 17.4 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAP86350.1 - 0.00011 21.7 0.0 0.00022 20.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAP86350.1 - 0.011 14.6 2.8 0.25 10.2 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF2570 PF10828.3 GAP86350.1 - 0.025 14.1 4.0 0.059 12.9 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) NmrA PF05368.8 GAP86350.1 - 0.082 12.1 0.6 0.15 11.2 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family CagE_TrbE_VirB PF03135.9 GAP86350.1 - 0.22 11.2 1.5 0.45 10.2 1.1 1.6 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system ABC_tran_2 PF12848.2 GAP86350.1 - 6.1 6.7 16.0 3.2 7.6 9.1 2.0 1 1 0 1 1 1 0 ABC transporter G-patch PF01585.18 GAP86351.1 - 2.6e-08 33.5 0.1 5.1e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 GAP86351.1 - 0.43 10.4 0.1 0.43 10.4 0.1 2.4 3 0 0 3 3 3 0 DExH-box splicing factor binding site Sec1 PF00995.18 GAP86352.1 - 1e-140 470.0 0.0 1.2e-140 469.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Apo-CIII PF05778.7 GAP86352.1 - 0.042 13.2 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) Npa1 PF11707.3 GAP86354.1 - 1.2e-78 264.4 0.0 2e-78 263.6 0.0 1.4 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal DIM1 PF02966.11 GAP86355.1 - 4.5e-66 220.3 0.1 5.1e-66 220.2 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.1 GAP86355.1 - 0.023 14.8 0.2 0.04 14.0 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like DHH PF01368.15 GAP86355.1 - 0.068 12.8 0.1 0.082 12.5 0.1 1.1 1 0 0 1 1 1 0 DHH family MOR2-PAG1_N PF14222.1 GAP86356.1 - 3.5e-201 669.6 0.0 6.5e-201 668.7 0.0 1.5 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 GAP86356.1 - 1.2e-82 277.6 0.4 4.2e-82 275.8 0.0 2.3 3 0 0 3 3 3 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 GAP86356.1 - 6e-42 143.3 3.6 2.9e-18 64.9 0.0 3.2 2 1 1 3 3 3 3 Cell morphogenesis central region HEAT PF02985.17 GAP86356.1 - 0.08 13.0 6.3 3.3 8.0 0.0 6.1 7 0 0 7 7 7 0 HEAT repeat Cnd1 PF12717.2 GAP86356.1 - 0.096 12.5 2.5 0.38 10.5 0.0 3.3 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 GAP86356.1 - 0.18 12.3 2.3 56 4.4 0.0 5.0 4 0 0 4 4 4 0 HEAT-like repeat FAD_binding_1 PF00667.15 GAP86357.1 - 1e-63 214.7 0.0 1.6e-63 214.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 GAP86357.1 - 1.9e-34 118.7 0.7 5.2e-34 117.3 0.5 1.8 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 GAP86357.1 - 3.1e-23 82.4 0.2 6.6e-22 78.1 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 GAP86357.1 - 0.022 14.7 0.2 0.17 11.9 0.0 2.4 2 0 0 2 2 2 0 Flavodoxin domain ATP-synt_F PF01990.12 GAP86357.1 - 0.025 14.9 0.1 0.057 13.8 0.0 1.6 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit Shikimate_DH PF01488.15 GAP86357.1 - 0.12 12.4 0.2 0.29 11.2 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RRM_1 PF00076.17 GAP86358.1 - 3.7e-20 71.3 0.0 7.5e-10 38.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP86358.1 - 1e-14 54.2 0.0 1.3e-06 28.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP86358.1 - 8.9e-05 22.2 0.0 0.29 10.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RIO1 PF01163.17 GAP86359.1 - 1e-38 132.6 0.0 2.6e-26 92.1 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 GAP86359.1 - 2.9e-30 104.1 0.0 5.1e-30 103.3 0.0 1.4 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 GAP86359.1 - 2.6e-08 33.9 2.2 8.2e-05 22.4 1.2 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 GAP86359.1 - 0.00062 18.8 0.1 0.045 12.7 0.1 2.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PaaX PF07848.7 GAP86359.1 - 0.021 14.8 0.1 0.052 13.5 0.1 1.7 1 0 0 1 1 1 0 PaaX-like protein CobT PF06213.7 GAP86359.1 - 0.62 9.1 12.7 0.99 8.4 8.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Glypican PF01153.14 GAP86359.1 - 5.8 5.4 6.0 8 4.9 4.2 1.1 1 0 0 1 1 1 0 Glypican PC_rep PF01851.17 GAP86360.1 - 6.3e-17 60.7 15.5 7.1e-05 22.8 0.1 8.7 10 0 0 10 10 10 4 Proteasome/cyclosome repeat HEAT_2 PF13646.1 GAP86360.1 - 3.6e-08 33.5 0.2 0.0021 18.2 0.0 3.8 3 1 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 GAP86360.1 - 0.023 15.1 0.1 0.38 11.3 0.0 3.2 2 1 1 3 3 3 0 HEAT-like repeat NAD_binding_5 PF07994.7 GAP86360.1 - 0.07 12.6 0.1 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase DEAD PF00270.24 GAP86361.1 - 4.5e-30 104.3 0.1 2.1e-29 102.1 0.0 2.2 2 2 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP86361.1 - 2.6e-20 72.0 1.2 4.1e-20 71.4 0.0 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 GAP86361.1 - 1e-17 63.6 1.2 1e-17 63.6 0.9 2.2 2 0 0 2 2 2 1 DBP10CT (NUC160) domain DnaJ PF00226.26 GAP86362.1 - 7.8e-14 51.1 2.4 1.1e-13 50.6 0.6 2.1 2 0 0 2 2 2 1 DnaJ domain HEAT PF02985.17 GAP86363.1 - 0.00017 21.4 0.9 0.19 11.8 0.0 4.2 3 0 0 3 3 3 1 HEAT repeat Arm PF00514.18 GAP86363.1 - 0.00038 20.1 0.2 1.6 8.6 0.0 3.1 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 GAP86363.1 - 0.00053 20.3 0.1 2.3 8.6 0.0 3.7 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 GAP86363.1 - 0.086 13.1 4.8 0.84 9.9 0.1 3.8 4 0 0 4 4 4 0 HEAT repeats BUD22 PF09073.5 GAP86363.1 - 4.7 6.1 8.3 7.4 5.5 5.7 1.2 1 0 0 1 1 1 0 BUD22 DUF202 PF02656.10 GAP86365.1 - 4.4e-17 62.0 0.5 4.4e-17 62.0 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) PsbH PF00737.15 GAP86365.1 - 0.059 12.9 0.1 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein PsbI PF02532.9 GAP86365.1 - 0.13 11.9 3.6 0.26 10.9 0.3 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) MatE PF01554.13 GAP86366.1 - 9.1e-58 194.4 30.0 2.1e-29 102.2 5.7 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 GAP86366.1 - 0.0027 17.5 38.6 0.012 15.4 3.8 3.7 1 1 1 3 3 3 2 Polysaccharide biosynthesis C-terminal domain YWFCY PF14293.1 GAP86366.1 - 0.1 12.4 0.8 0.55 10.1 0.1 2.3 2 0 0 2 2 2 0 YWFCY protein YbgT_YccB PF08173.6 GAP86366.1 - 1.1 9.1 7.8 0.37 10.6 1.6 3.2 3 0 0 3 3 3 0 Membrane bound YbgT-like protein NUDIX PF00293.23 GAP86367.1 - 5.8e-28 97.2 0.0 9.2e-28 96.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Acetyltransf_7 PF13508.1 GAP86368.1 - 8.5e-09 35.4 0.6 1.4e-08 34.7 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAP86368.1 - 4.7e-07 29.7 1.2 5.9e-07 29.4 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 GAP86368.1 - 6.7e-06 25.9 0.2 2.1e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAP86368.1 - 0.00018 21.1 0.0 0.00058 19.5 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 GAP86368.1 - 0.00055 20.0 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAP86368.1 - 0.055 13.3 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase RPA_C PF08784.6 GAP86369.1 - 2.9e-17 62.9 0.0 6e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 GAP86369.1 - 9.4e-09 35.0 0.2 1.9e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Lon_C PF05362.8 GAP86370.1 - 7.2e-63 211.5 0.1 1.4e-62 210.6 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 GAP86370.1 - 7.3e-23 81.2 0.1 3.3e-22 79.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 GAP86370.1 - 1.3e-22 80.4 0.0 3.4e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA_5 PF07728.9 GAP86370.1 - 1.7e-08 34.2 0.0 5e-08 32.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 GAP86370.1 - 2.5e-08 33.4 0.1 2.7e-07 30.1 0.0 2.4 2 1 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 GAP86370.1 - 1.9e-06 28.0 0.5 7.6e-06 26.0 0.0 2.2 3 0 0 3 3 2 1 AAA ATPase domain RuvB_N PF05496.7 GAP86370.1 - 1.9e-06 27.1 0.0 8.5e-06 24.9 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 GAP86370.1 - 2e-05 25.3 0.0 6e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 GAP86370.1 - 3.5e-05 23.4 0.0 0.0001 21.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 GAP86370.1 - 4e-05 22.5 0.2 0.00025 19.9 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus AAA_2 PF07724.9 GAP86370.1 - 0.00013 21.9 0.0 0.00062 19.7 0.0 2.2 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 GAP86370.1 - 0.00017 21.0 0.0 0.00046 19.6 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 GAP86370.1 - 0.00019 21.5 0.0 0.0073 16.4 0.0 3.0 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 GAP86370.1 - 0.00041 20.2 0.0 0.011 15.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 GAP86370.1 - 0.0021 17.1 0.0 0.0069 15.5 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 GAP86370.1 - 0.0024 17.5 0.1 0.0082 15.8 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 GAP86370.1 - 0.0059 16.4 0.1 0.018 14.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAP86370.1 - 0.0063 16.8 0.0 0.026 14.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 GAP86370.1 - 0.0074 16.6 5.9 0.014 15.7 0.0 2.9 1 1 1 2 2 1 1 AAA domain RNA_helicase PF00910.17 GAP86370.1 - 0.01 16.0 0.0 0.079 13.1 0.0 2.4 2 0 0 2 2 2 1 RNA helicase Arch_ATPase PF01637.13 GAP86370.1 - 0.01 15.5 0.1 0.49 10.0 0.0 3.0 2 1 1 3 3 3 0 Archaeal ATPase Mg_chelatase PF01078.16 GAP86370.1 - 0.028 13.5 0.4 0.14 11.2 0.1 2.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.10 GAP86370.1 - 0.036 12.7 0.0 0.06 12.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_25 PF13481.1 GAP86370.1 - 0.036 13.4 0.0 0.24 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 GAP86370.1 - 0.04 13.5 0.1 0.19 11.3 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_PrkA PF08298.6 GAP86370.1 - 0.047 12.3 0.0 0.35 9.5 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain UPF0079 PF02367.12 GAP86370.1 - 0.06 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 CCDC-167 PF15188.1 GAP86370.1 - 0.065 13.1 2.3 0.15 12.0 0.7 2.3 2 0 0 2 2 1 0 Coiled-coil domain-containing protein 167 ABC_tran PF00005.22 GAP86370.1 - 0.17 12.2 1.5 1.8 8.8 0.0 3.2 3 1 0 3 3 2 0 ABC transporter SOBP PF15279.1 GAP86371.1 - 0.36 11.1 6.3 0.37 11.1 4.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Zn_clus PF00172.13 GAP86373.1 - 8.2e-07 28.8 10.9 1.3e-06 28.1 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 GAP86373.1 - 0.23 11.2 0.0 0.5 10.1 0.0 1.5 1 0 0 1 1 1 0 PAS fold DNA_mis_repair PF01119.14 GAP86375.1 - 1.4e-33 114.8 0.0 2.5e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 GAP86375.1 - 4.9e-14 52.1 0.0 1e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 GAP86375.1 - 8.2e-11 41.6 0.0 2e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Myb_DNA-binding PF00249.26 GAP86376.1 - 0.021 14.8 0.4 0.25 11.4 0.3 2.3 1 1 0 1 1 1 0 Myb-like DNA-binding domain PDZ_1 PF12812.2 GAP86377.1 - 2.8e-52 174.5 0.0 1.8e-32 111.0 0.0 2.7 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.1 GAP86377.1 - 8.9e-17 60.7 0.2 8.9e-08 31.9 0.0 4.5 4 0 0 4 4 4 3 PDZ domain Trypsin_2 PF13365.1 GAP86377.1 - 7.7e-14 51.7 1.6 1.3e-11 44.5 0.0 3.0 3 0 0 3 3 3 1 Trypsin-like peptidase domain PDZ PF00595.19 GAP86377.1 - 8.3e-12 45.1 0.0 6.9e-06 26.1 0.0 3.8 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 GAP86377.1 - 3.9e-05 23.3 0.7 0.0029 17.3 0.1 3.3 3 0 0 3 3 3 1 Tricorn protease PDZ domain Peptidase_S46 PF10459.4 GAP86377.1 - 0.19 10.1 0.3 0.77 8.0 0.1 1.8 2 0 0 2 2 2 0 Peptidase S46 Peptidase_S7 PF00949.16 GAP86377.1 - 0.23 10.8 1.0 0.51 9.7 0.2 1.8 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.11 GAP86377.1 - 0.32 10.2 0.3 0.47 9.7 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) AUX_IAA PF02309.11 GAP86378.1 - 0.63 9.7 4.6 0.85 9.3 3.2 1.2 1 0 0 1 1 1 0 AUX/IAA family Peptidase_S64 PF08192.6 GAP86378.1 - 3.4 5.8 9.7 4.5 5.4 6.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF3827 PF12877.2 GAP86378.1 - 7.9 4.4 11.8 9.7 4.1 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) HsbA PF12296.3 GAP86379.1 - 2.6e-09 36.9 0.0 3.5e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Zn_clus PF00172.13 GAP86380.1 - 2.3e-09 37.0 9.6 2.3e-09 37.0 6.7 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATP-synt_C PF00137.16 GAP86381.1 - 3.6e-29 100.4 25.0 8.8e-17 60.7 5.5 2.3 2 0 0 2 2 2 2 ATP synthase subunit C Oxidored_q2 PF00420.19 GAP86381.1 - 1.4 8.5 6.6 13 5.4 4.3 2.6 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L tRNA_bind PF01588.15 GAP86382.1 - 2.8e-22 78.3 0.6 2.4e-21 75.3 0.4 2.3 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 GAP86382.1 - 2.9e-07 30.8 0.0 7.9e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAP86382.1 - 0.00074 19.3 0.0 0.0019 18.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAP86382.1 - 0.014 15.3 0.0 0.062 13.2 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain TRM PF02005.11 GAP86383.1 - 0.24 10.3 0.8 0.32 9.8 0.6 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase RNA_pol PF00940.14 GAP86384.1 - 4.6e-162 539.1 0.0 6.2e-162 538.7 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 GAP86384.1 - 8.2e-72 242.1 0.2 2e-71 240.8 0.1 1.6 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal Oligomerisation PF02410.10 GAP86385.1 - 0.00058 19.8 0.0 0.0026 17.7 0.0 2.1 1 1 0 1 1 1 1 Oligomerisation domain DHHA2 PF02833.9 GAP86386.1 - 2.2e-13 50.5 0.0 3.6e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 GAP86386.1 - 2.4e-06 27.2 0.0 2.3e-05 24.0 0.0 2.0 1 1 0 1 1 1 1 DHH family Pkinase PF00069.20 GAP86387.1 - 1.7e-24 86.3 0.0 3.3e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 GAP86387.1 - 1.7e-15 56.1 0.8 1e-08 34.7 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat HEAT PF02985.17 GAP86387.1 - 1.7e-11 43.1 7.6 0.039 14.0 0.0 6.8 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 GAP86387.1 - 5.4e-07 29.7 2.3 0.14 12.4 0.0 4.4 3 1 2 5 5 5 4 HEAT repeats Pkinase_Tyr PF07714.12 GAP86387.1 - 4.8e-05 22.5 0.0 7.5e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.1 GAP86387.1 - 0.027 14.9 5.9 0.25 11.8 0.4 3.9 4 0 0 4 4 4 0 HEAT-like repeat SH3_9 PF14604.1 GAP86388.1 - 8.6e-08 31.6 0.1 2.2e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Glycophorin_A PF01102.13 GAP86388.1 - 8.1e-05 22.3 0.0 0.00024 20.8 0.0 1.8 1 0 0 1 1 1 1 Glycophorin A SH3_1 PF00018.23 GAP86388.1 - 0.00012 21.3 0.1 0.00025 20.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain IncA PF04156.9 GAP86388.1 - 0.16 11.5 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 IncA protein EphA2_TM PF14575.1 GAP86388.1 - 0.16 12.3 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CbiM PF01891.11 GAP86388.1 - 0.17 11.4 1.8 0.34 10.4 1.2 1.4 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region Gly-zipper_Omp PF13488.1 GAP86388.1 - 9.3 5.9 19.9 3.2 7.4 3.2 2.4 2 0 0 2 2 2 0 Glycine zipper FAM176 PF14851.1 GAP86390.1 - 0.048 13.3 0.0 0.058 13.0 0.0 1.1 1 0 0 1 1 1 0 FAM176 family Ribonucleas_3_3 PF14622.1 GAP86391.1 - 8.1e-09 35.5 0.0 0.00073 19.5 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.21 GAP86391.1 - 1.2e-05 25.6 0.0 2.7e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease III domain PLA2_B PF01735.13 GAP86392.1 - 2.4e-26 91.9 0.0 5.1e-26 90.8 0.0 1.5 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Serglycin PF04360.7 GAP86392.1 - 1.9 8.2 5.1 4.1 7.1 3.6 1.5 1 0 0 1 1 1 0 Serglycin Acetyltransf_1 PF00583.19 GAP86394.1 - 1e-05 25.4 0.1 1.5e-05 24.9 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Sigma70_ner PF04546.8 GAP86395.1 - 0.2 11.2 5.1 0.33 10.5 3.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 GAP86395.1 - 2.3 7.7 9.9 3.6 7.0 6.9 1.2 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 GAP86395.1 - 3.1 6.9 9.1 4.1 6.5 6.3 1.1 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.20 GAP86396.1 - 4e-35 121.2 0.0 4.9e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP86396.1 - 3.2e-10 39.5 0.0 4.5e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP86396.1 - 0.002 17.1 0.0 0.0033 16.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAP86396.1 - 0.033 13.9 0.0 0.79 9.4 0.0 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family muHD PF10291.4 GAP86397.1 - 3.2e-66 223.1 0.0 5.3e-66 222.4 0.0 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 GAP86397.1 - 6.7e-14 51.8 0.2 6.7e-14 51.8 0.2 2.2 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain P16-Arc PF04699.9 GAP86397.1 - 0.15 12.0 2.7 0.49 10.3 0.0 2.6 2 1 0 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF2935 PF11155.3 GAP86397.1 - 0.22 11.6 2.7 0.9 9.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) AAA_13 PF13166.1 GAP86397.1 - 0.23 9.8 9.9 0.35 9.2 6.9 1.2 1 0 0 1 1 1 0 AAA domain Syntaxin PF00804.20 GAP86397.1 - 0.46 10.6 8.5 0.88 9.7 2.7 3.2 3 1 0 3 3 3 0 Syntaxin DUF883 PF05957.8 GAP86397.1 - 0.85 10.0 11.5 2 8.8 2.0 3.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) V_ATPase_I PF01496.14 GAP86397.1 - 0.88 7.3 7.3 1.4 6.7 5.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF106 PF01956.11 GAP86397.1 - 2.1 7.8 4.8 5.5 6.4 3.4 1.7 1 0 0 1 1 1 0 Integral membrane protein DUF106 MAD PF05557.8 GAP86398.1 - 1.3e-55 188.8 70.2 1.9e-55 188.3 48.7 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Reo_sigmaC PF04582.7 GAP86398.1 - 3 6.9 18.6 0.82 8.7 3.2 2.7 3 0 0 3 3 3 0 Reovirus sigma C capsid protein Mmp37 PF09139.6 GAP86399.1 - 2.7e-133 444.1 0.0 3.2e-133 443.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 Aldo_ket_red PF00248.16 GAP86400.1 - 1.6e-73 247.0 0.0 1.8e-73 246.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_23 PF13384.1 GAP86400.1 - 0.018 14.6 1.1 0.22 11.2 0.0 3.0 4 0 0 4 4 4 0 Homeodomain-like domain Aldedh PF00171.17 GAP86402.1 - 2.1e-60 204.4 2.6 4.9e-34 117.4 0.1 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Aldedh PF00171.17 GAP86403.1 - 9.2e-34 116.5 0.0 9.9e-34 116.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cellulase PF00150.13 GAP86404.1 - 1.2e-33 116.5 0.6 1.8e-33 115.9 0.4 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.9 GAP86404.1 - 3.1e-22 78.2 5.9 2.1e-21 75.5 2.8 3.1 3 0 0 3 3 3 1 Carbohydrate binding domain X2 Cas_Cas5d PF09704.5 GAP86404.1 - 0.041 13.4 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas5) tRNA-synt_1 PF00133.17 GAP86405.1 - 9.7e-35 119.6 0.0 2.6e-14 52.1 0.0 3.6 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 GAP86405.1 - 6.8e-18 64.4 0.2 1.6e-10 40.2 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 GAP86405.1 - 4.8e-12 45.8 0.0 1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 GAP86405.1 - 1.3e-05 24.5 0.0 2.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Ank_2 PF12796.2 GAP86407.1 - 5.3e-29 100.3 0.1 1.3e-10 41.4 0.0 4.4 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAP86407.1 - 5.6e-21 73.2 0.4 0.00013 21.5 0.0 7.8 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 GAP86407.1 - 1.1e-20 73.1 0.2 6.4e-08 32.6 0.0 6.0 4 2 3 7 7 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAP86407.1 - 1.5e-14 54.0 1.3 2.7e-06 27.7 0.0 6.3 6 1 1 7 7 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP86407.1 - 2.6e-14 51.9 0.8 0.081 13.2 0.0 8.1 8 0 0 8 8 8 3 Ankyrin repeat NACHT PF05729.7 GAP86407.1 - 1.9e-08 34.1 0.0 4.9e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 GAP86407.1 - 9.4e-07 28.9 0.1 5.1e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAP86407.1 - 0.0016 18.5 0.0 0.027 14.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 GAP86407.1 - 0.0042 16.8 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase Sigma54_activ_2 PF14532.1 GAP86407.1 - 0.0075 16.3 0.1 7.9 6.5 0.0 3.6 4 0 0 4 4 4 1 Sigma-54 interaction domain AAA_19 PF13245.1 GAP86407.1 - 0.037 13.7 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain DUF2075 PF09848.4 GAP86407.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Scs3p PF10261.4 GAP86408.1 - 1.3e-31 109.5 0.4 1.5e-31 109.2 0.3 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Scs3p PF10261.4 GAP86409.1 - 1.3e-07 30.9 0.6 2e-07 30.3 0.2 1.4 2 0 0 2 2 2 1 Inositol phospholipid synthesis and fat-storage-inducing TM DUF3439 PF11921.3 GAP86409.1 - 0.0015 18.2 6.6 0.0023 17.6 4.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) gpUL132 PF11359.3 GAP86409.1 - 1.9 7.7 5.3 2.8 7.2 3.7 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 SSP160 PF06933.6 GAP86409.1 - 3.8 5.3 11.4 4.6 5.0 7.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Pectate_lyase_3 PF12708.2 GAP86410.1 - 6e-81 271.8 17.8 2.1e-64 217.7 7.7 2.8 2 1 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 GAP86410.1 - 1.6e-05 24.2 2.5 0.039 13.4 0.2 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase RestrictionMunI PF11407.3 GAP86410.1 - 0.045 13.3 0.1 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 Type II restriction enzyme MunI Glyco_hydro_1 PF00232.13 GAP86411.1 - 1.2e-150 501.6 0.1 1.5e-150 501.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DUF4137 PF13593.1 GAP86412.1 - 6.1e-80 268.6 17.1 7.5e-80 268.3 11.8 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Pro-kuma_activ PF09286.6 GAP86413.1 - 5.8e-32 110.6 0.0 9.3e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 GAP86413.1 - 1.4e-08 34.2 0.0 2.3e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Subtilase family Rsm22 PF09243.5 GAP86414.1 - 0.016 14.2 0.1 0.034 13.1 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_18 PF12847.2 GAP86415.1 - 1.5e-13 51.2 0.0 2.5e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP86415.1 - 5.5e-09 35.7 0.0 5.8e-08 32.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP86415.1 - 1.2e-05 25.2 0.1 2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP86415.1 - 6.5e-05 22.7 0.0 0.00029 20.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP86415.1 - 6.9e-05 23.2 0.1 0.00019 21.8 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP86415.1 - 0.0026 18.0 0.0 0.0044 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP86415.1 - 0.011 16.2 0.0 0.12 12.8 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_32 PF13679.1 GAP86415.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.8 GAP86415.1 - 0.022 14.8 0.1 0.05 13.7 0.0 1.6 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase HEAT PF02985.17 GAP86416.1 - 5.3e-43 141.2 14.5 0.0029 17.5 0.1 13.2 14 0 0 14 14 14 12 HEAT repeat HEAT_2 PF13646.1 GAP86416.1 - 5.1e-31 106.8 2.5 1.8e-07 31.3 0.0 7.7 3 3 4 7 7 7 6 HEAT repeats Vac14_Fab1_bd PF12755.2 GAP86416.1 - 3.9e-11 43.1 3.3 0.012 15.9 0.1 7.5 5 2 4 9 9 9 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 GAP86416.1 - 2.6e-07 30.9 11.8 0.2 12.1 0.0 9.3 9 2 3 12 12 12 1 HEAT-like repeat Adaptin_N PF01602.15 GAP86416.1 - 4e-06 25.4 8.9 0.061 11.6 1.4 4.6 2 1 0 3 3 3 3 Adaptin N terminal region CLASP_N PF12348.3 GAP86416.1 - 0.00044 19.6 1.3 7 5.9 0.0 4.4 2 2 1 4 4 4 2 CLASP N terminal DUF2435 PF10363.4 GAP86416.1 - 0.0019 18.0 5.8 0.96 9.3 0.1 4.5 4 0 0 4 4 4 1 Protein of unknown function (DUF2435) Arm PF00514.18 GAP86416.1 - 0.017 14.9 5.2 1.6 8.6 0.0 5.0 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 GAP86416.1 - 0.073 12.9 6.3 9.7 5.9 0.1 5.5 3 2 3 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 GAP86416.1 - 0.11 10.7 3.5 0.58 8.3 0.0 2.9 2 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit Imm25 PF15571.1 GAP86416.1 - 0.76 9.9 4.6 10 6.2 0.0 4.1 4 1 1 5 5 5 0 Immunity protein 25 Myotub-related PF06602.9 GAP86417.1 - 2.8e-122 407.8 0.0 3.6e-122 407.5 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 GAP86417.1 - 0.029 14.6 0.0 0.071 13.3 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 GAP86417.1 - 0.2 10.9 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ribosomal_S3_C PF00189.15 GAP86418.1 - 1e-16 60.8 0.0 2.3e-16 59.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 GAP86418.1 - 3.2e-12 45.8 0.0 6e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 GAP86418.1 - 0.056 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Mg_trans_NIPA PF05653.9 GAP86419.1 - 1.6e-105 352.4 11.1 1.9e-105 352.1 7.7 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 GAP86419.1 - 2.5e-09 37.3 1.7 2.5e-09 37.3 1.2 3.6 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 GAP86419.1 - 7.9e-06 25.9 4.8 7.9e-06 25.9 3.3 3.0 2 1 0 3 3 3 1 EamA-like transporter family DUF1772 PF08592.6 GAP86419.1 - 3.8 7.2 9.6 5.3 6.7 0.3 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) DUF2420 PF10336.4 GAP86420.1 - 0.00074 19.0 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Adap_comp_sub PF00928.16 GAP86421.1 - 6.4e-15 54.9 0.0 1e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 GAP86421.1 - 3.3e-09 36.5 0.1 5.4e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.6 GAP86421.1 - 0.059 13.5 0.2 0.12 12.5 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) Apc4 PF12896.2 GAP86422.1 - 9.6e-58 194.9 3.5 1.5e-57 194.2 1.7 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 4 WD40 PF00400.27 GAP86422.1 - 0.0003 20.5 0.0 0.015 15.1 0.0 3.1 2 0 0 2 2 2 1 WD domain, G-beta repeat T2SS-T3SS_pil_N PF13629.1 GAP86422.1 - 0.037 13.5 0.0 0.69 9.4 0.0 2.5 2 0 0 2 2 2 0 Pilus formation protein N terminal region AMP-binding PF00501.23 GAP86423.1 - 6.1e-69 232.4 0.0 8.1e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAP86423.1 - 6.2e-17 62.3 0.1 1.2e-16 61.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain KTI12 PF08433.5 GAP86424.1 - 3.9e-65 219.7 0.0 5.9e-65 219.1 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 GAP86424.1 - 7.9e-06 25.7 0.9 1.1e-05 25.3 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAP86424.1 - 0.00034 21.4 0.2 0.00088 20.0 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAP86424.1 - 0.013 15.6 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAP86424.1 - 0.021 15.0 0.0 0.075 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain 6PF2K PF01591.13 GAP86424.1 - 0.031 13.3 0.0 0.053 12.5 0.0 1.3 1 1 0 1 1 1 0 6-phosphofructo-2-kinase AAA_14 PF13173.1 GAP86424.1 - 0.15 11.9 0.0 0.54 10.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF3628 PF12300.3 GAP86424.1 - 6.3 6.8 21.7 0.22 11.5 2.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3628) Pyr_redox_3 PF13738.1 GAP86425.1 - 3.6e-26 92.4 0.0 3.8e-25 89.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAP86425.1 - 2.2e-09 36.6 0.0 1.8e-06 27.0 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAP86425.1 - 4.1e-09 36.6 0.0 6.6e-08 32.6 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAP86425.1 - 8.5e-09 34.1 0.0 3e-08 32.3 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 GAP86425.1 - 5.2e-07 29.5 1.7 0.0097 15.6 0.0 3.9 3 1 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 GAP86425.1 - 0.00028 20.8 0.0 0.00068 19.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAP86425.1 - 0.00082 18.3 3.8 0.093 11.6 0.5 3.0 2 2 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 GAP86425.1 - 0.00098 18.2 0.4 0.0064 15.6 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 GAP86425.1 - 0.096 11.5 0.6 0.97 8.2 0.2 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein SNF5 PF04855.7 GAP86427.1 - 6.6e-74 248.4 0.2 1.1e-73 247.7 0.1 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 INO80_Ies4 PF08193.6 GAP86427.1 - 0.0016 18.4 4.3 0.0016 18.4 3.0 3.0 2 1 1 3 3 3 1 INO80 complex subunit Ies4 TolB_N PF04052.8 GAP86427.1 - 0.12 12.5 0.1 4.6 7.3 0.0 3.2 3 1 1 4 4 4 0 TolB amino-terminal domain Peptidase_M24 PF00557.19 GAP86428.1 - 9.2e-08 31.9 0.0 1.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 PHD PF00628.24 GAP86429.1 - 1.4e-12 47.1 24.3 3.7e-09 36.1 7.3 2.4 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.1 GAP86429.1 - 0.00054 19.2 8.2 0.12 11.6 3.4 2.8 2 0 0 2 2 2 2 PHD-finger Prok-RING_1 PF14446.1 GAP86429.1 - 0.01 15.5 2.1 0.01 15.5 1.5 2.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-PHD-like PF15446.1 GAP86429.1 - 0.027 13.7 10.3 0.13 11.5 2.3 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Nucleo_P87 PF07267.6 GAP86429.1 - 6 5.4 4.3 15 4.0 3.0 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PUF PF00806.14 GAP86430.1 - 1.5e-27 93.4 0.0 3.2e-05 23.1 0.0 5.9 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 GAP86430.1 - 1.4e-12 47.0 0.0 2.9e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP86430.1 - 4.3e-05 23.2 0.0 8.4e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP86430.1 - 6.8e-05 22.7 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3439 PF11921.3 GAP86432.1 - 0.015 15.0 3.8 0.035 13.8 2.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Pep3_Vps18 PF05131.9 GAP86433.1 - 1.1e-48 164.3 0.3 2.6e-48 163.2 0.2 1.6 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 GAP86433.1 - 4.2e-10 39.3 6.8 4e-08 32.9 0.0 3.5 3 1 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 GAP86433.1 - 0.00064 19.5 1.5 0.00064 19.5 1.0 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 GAP86433.1 - 0.00093 18.8 1.7 0.0023 17.6 1.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Vps39_2 PF10367.4 GAP86433.1 - 0.011 15.8 0.1 0.046 13.8 0.0 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 DUF2175 PF09943.4 GAP86433.1 - 0.022 14.8 0.1 0.073 13.1 0.1 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C3HC4_2 PF13923.1 GAP86433.1 - 0.078 13.0 1.6 0.2 11.7 1.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAP86433.1 - 0.099 12.7 0.1 0.28 11.3 0.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 GAP86433.1 - 2.2 7.9 5.6 0.38 10.4 0.8 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Methyltransf_23 PF13489.1 GAP86434.1 - 1.6e-17 63.6 0.0 1.1e-16 60.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP86434.1 - 1.1e-09 38.0 0.0 6.7e-09 35.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP86434.1 - 2e-09 37.7 0.0 7.3e-09 36.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP86434.1 - 2.7e-08 34.1 0.0 8.7e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP86434.1 - 4.6e-08 33.6 0.1 3.9e-07 30.6 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP86434.1 - 5.2e-05 22.4 0.0 0.00012 21.2 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 GAP86434.1 - 0.0015 17.5 0.0 0.0035 16.4 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 GAP86434.1 - 0.0026 17.1 0.0 0.0059 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 GAP86434.1 - 0.0036 16.4 0.1 0.0072 15.4 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 GAP86434.1 - 0.012 15.9 0.0 0.037 14.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_2 PF00891.13 GAP86434.1 - 0.043 13.0 0.0 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_16 PF10294.4 GAP86434.1 - 0.065 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Epimerase PF01370.16 GAP86435.1 - 5.4e-54 183.1 0.1 6.8e-54 182.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAP86435.1 - 2.7e-22 79.0 0.0 2.7e-21 75.7 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 GAP86435.1 - 5.3e-21 74.6 0.2 6.2e-20 71.1 0.1 2.3 1 1 1 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 GAP86435.1 - 5.4e-21 74.7 0.0 7.3e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 GAP86435.1 - 1.8e-19 69.5 0.0 2.5e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAP86435.1 - 6.9e-08 32.7 0.0 1.1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 GAP86435.1 - 0.014 15.2 0.0 0.074 12.9 0.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase TPT PF03151.11 GAP86436.1 - 3.5e-18 65.7 12.0 3.5e-18 65.7 8.3 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 GAP86436.1 - 3.2e-05 23.9 11.8 3.2e-05 23.9 8.2 2.8 2 1 0 2 2 2 1 EamA-like transporter family PX PF00787.19 GAP86437.1 - 4.4e-19 68.3 0.0 1.2e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 GAP86437.1 - 8.9e-16 57.8 11.5 2.3e-10 40.1 0.5 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR_3_WASP_bdg PF10456.4 GAP86437.1 - 0.0019 17.5 0.2 0.012 14.9 0.2 2.0 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein ATP-synt_C PF00137.16 GAP86438.1 - 3.6e-24 84.4 22.0 2e-15 56.4 7.1 2.0 2 0 0 2 2 2 2 ATP synthase subunit C TCR_zetazeta PF11628.3 GAP86438.1 - 0.043 13.2 1.6 6.2 6.3 0.0 2.6 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 zeta chain DUF3816 PF12822.2 GAP86438.1 - 0.23 11.3 8.0 0.16 11.8 4.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) Claudin_2 PF13903.1 GAP86438.1 - 5.8 6.5 8.8 0.28 10.8 1.1 1.9 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction HET PF06985.6 GAP86439.1 - 2.5e-23 82.7 0.0 4e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GMC_oxred_C PF05199.8 GAP86440.1 - 2.3e-08 34.4 0.0 1.4e-07 31.8 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase Asp PF00026.18 GAP86441.1 - 1.9e-69 234.3 3.2 2.2e-69 234.1 2.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAP86441.1 - 1.9e-11 44.1 1.3 3.6e-11 43.2 0.2 2.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 GAP86441.1 - 7e-08 32.1 0.1 2.2e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 GAP86441.1 - 4.3e-06 27.1 1.4 0.033 14.7 0.2 3.6 2 1 0 2 2 2 2 Aspartyl protease DNA_ligase_A_M PF01068.16 GAP86442.1 - 1.4e-55 187.8 0.6 3.4e-44 150.6 0.1 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 GAP86442.1 - 1.6e-52 177.8 0.0 1.6e-52 177.8 0.0 1.9 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 GAP86442.1 - 4.8e-28 97.4 0.0 2e-27 95.4 0.0 2.2 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region Nop14 PF04147.7 GAP86442.1 - 0.39 8.5 24.8 0.049 11.5 14.2 1.6 2 0 0 2 2 2 0 Nop14-like family LRR_1 PF00560.28 GAP86444.1 - 0.08 13.0 2.7 17 5.9 0.1 5.5 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 GAP86444.1 - 1.8 9.1 11.8 6.7 7.3 0.2 6.1 7 0 0 7 7 7 0 Leucine rich repeat LRR_6 PF13516.1 GAP86444.1 - 1.9 8.7 4.2 57 4.2 0.2 4.3 4 0 0 4 4 4 0 Leucine Rich repeat Pkinase PF00069.20 GAP86446.1 - 4.7e-67 225.8 0.0 7.6e-67 225.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP86446.1 - 9.6e-49 165.7 0.0 1.6e-48 165.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 GAP86446.1 - 1e-28 99.3 0.0 3.1e-28 97.7 0.0 1.9 2 0 0 2 2 2 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 GAP86446.1 - 1.3e-16 60.1 0.2 5.8e-16 58.0 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 GAP86446.1 - 5e-16 58.6 0.1 9.6e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 GAP86446.1 - 1.6e-13 50.9 0.0 3.3e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.1 GAP86446.1 - 2.7e-07 29.8 0.0 0.00013 20.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like SAM_PNT PF02198.11 GAP86446.1 - 0.0025 17.5 0.0 0.0045 16.7 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Ste50p-SAM PF09235.5 GAP86446.1 - 0.17 11.8 0.5 0.38 10.7 0.3 1.6 1 0 0 1 1 1 0 Ste50p, sterile alpha motif DUF1206 PF06724.6 GAP86448.1 - 0.056 13.2 1.4 0.12 12.1 0.9 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) FA_hydroxylase PF04116.8 GAP86449.1 - 5.8e-18 65.3 7.9 5.8e-18 65.3 5.5 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily TCTP PF00838.12 GAP86450.1 - 5.9e-59 198.7 1.4 6.6e-59 198.5 0.9 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Mis12 PF05859.7 GAP86452.1 - 1.5e-38 131.8 0.0 3.3e-38 130.7 0.0 1.6 1 1 0 1 1 1 1 Mis12 protein PPR_2 PF13041.1 GAP86453.1 - 1.5e-22 79.2 0.0 1.6e-05 24.7 0.0 7.8 5 3 4 9 9 9 4 PPR repeat family PPR_3 PF13812.1 GAP86453.1 - 5.1e-14 51.2 8.2 0.17 12.2 0.0 9.0 9 0 0 9 9 9 4 Pentatricopeptide repeat domain PPR PF01535.15 GAP86453.1 - 1.1e-09 37.6 0.2 0.21 11.6 0.0 6.2 5 0 0 5 5 5 3 PPR repeat PPR_1 PF12854.2 GAP86453.1 - 1e-06 28.1 0.0 0.17 11.3 0.0 5.0 5 0 0 5 5 5 2 PPR repeat TPR_14 PF13428.1 GAP86453.1 - 0.018 15.6 1.1 6 7.7 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat MRP-S27 PF10037.4 GAP86453.1 - 0.072 11.9 0.0 2.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 His_Phos_2 PF00328.17 GAP86454.1 - 7.9e-22 78.0 0.0 1.5e-19 70.5 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RRM_6 PF14259.1 GAP86455.1 - 2.7e-40 136.1 0.1 6.2e-11 42.1 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAP86455.1 - 2.1e-36 123.3 0.1 1.3e-11 43.9 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP86455.1 - 3.7e-19 68.3 0.6 0.00016 21.4 0.0 4.8 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 GAP86455.1 - 5.3e-11 41.9 4.9 5.3e-11 41.9 3.4 2.9 3 0 0 3 3 3 1 Putative RRM domain RRM_3 PF08777.6 GAP86455.1 - 8.2e-05 22.3 0.1 0.01 15.6 0.1 2.7 2 0 0 2 2 2 1 RNA binding motif RNA_bind PF08675.6 GAP86455.1 - 0.044 13.7 0.2 0.33 10.9 0.0 2.5 3 1 0 3 3 3 0 RNA binding domain NID PF07292.8 GAP86455.1 - 0.1 12.6 0.0 0.41 10.7 0.0 2.1 2 0 0 2 2 2 0 Nmi/IFP 35 domain (NID) Arginase PF00491.16 GAP86456.1 - 2.2e-90 302.7 0.1 2.6e-90 302.4 0.1 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 GAP86456.1 - 0.3 11.2 1.6 0.28 11.3 0.1 1.6 2 0 0 2 2 2 0 UPF0489 domain Ras PF00071.17 GAP86457.1 - 6.1e-53 178.5 0.0 7.2e-53 178.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAP86457.1 - 5.7e-16 59.0 0.0 9.1e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAP86457.1 - 1.7e-06 27.4 0.0 2.3e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PI3_PI4_kinase PF00454.22 GAP86459.1 - 2.9e-46 157.8 0.0 1.4e-45 155.5 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 GAP86459.1 - 8.6e-33 113.2 0.0 9.5e-32 109.8 0.0 2.6 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 GAP86459.1 - 3.3e-12 45.6 0.1 1.4e-11 43.6 0.0 2.1 2 0 0 2 2 2 1 FATC domain DUF3414 PF11894.3 GAP86460.1 - 0 1207.7 3.6 0 1207.2 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) AA_permease PF00324.16 GAP86461.1 - 1.4e-123 412.8 39.6 1.7e-123 412.5 27.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAP86461.1 - 1.8e-39 135.5 44.3 2.2e-39 135.2 30.7 1.0 1 0 0 1 1 1 1 Amino acid permease AAA PF00004.24 GAP86462.1 - 5.3e-52 175.5 0.0 1.9e-42 144.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAP86462.1 - 3.4e-09 36.9 0.0 0.0005 20.1 0.1 3.5 3 1 0 3 3 2 2 AAA ATPase domain IstB_IS21 PF01695.12 GAP86462.1 - 8.8e-06 25.2 0.0 0.00018 21.0 0.0 2.7 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_14 PF13173.1 GAP86462.1 - 1.1e-05 25.3 0.0 0.022 14.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 GAP86462.1 - 2.1e-05 24.4 0.0 4.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 GAP86462.1 - 7.3e-05 22.9 0.0 0.0038 17.3 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAP86462.1 - 0.00052 20.8 0.1 0.016 16.0 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAP86462.1 - 0.00061 19.4 0.1 0.038 13.7 0.1 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 GAP86462.1 - 0.00087 19.0 0.0 0.0043 16.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 GAP86462.1 - 0.0028 17.5 0.0 0.0098 15.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 GAP86462.1 - 0.0086 14.8 0.0 0.015 14.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 GAP86462.1 - 0.01 15.9 0.0 0.089 12.9 0.0 2.4 2 0 0 2 2 2 0 RNA helicase RuvB_N PF05496.7 GAP86462.1 - 0.029 13.4 0.0 0.062 12.3 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 GAP86462.1 - 0.044 13.8 0.0 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.1 GAP86462.1 - 0.053 13.4 1.8 0.082 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 GAP86462.1 - 0.058 13.6 0.0 0.058 13.6 0.0 3.3 3 0 0 3 3 2 0 AAA domain Mg_chelatase PF01078.16 GAP86462.1 - 0.064 12.4 0.1 0.14 11.3 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.12 GAP86462.1 - 0.075 11.8 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 GAP86462.1 - 0.079 12.4 0.0 4.3 6.7 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain Torsin PF06309.6 GAP86462.1 - 0.095 12.5 0.1 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Torsin AAA_3 PF07726.6 GAP86462.1 - 0.17 11.4 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 GAP86462.1 - 0.2 11.2 0.1 0.76 9.4 0.0 2.1 1 1 0 1 1 1 0 NACHT domain Dus PF01207.12 GAP86465.1 - 1.9e-58 197.7 0.0 2.9e-58 197.1 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 GAP86465.1 - 0.12 11.2 0.0 0.24 10.2 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase FAD_binding_3 PF01494.14 GAP86467.1 - 4.3e-19 68.7 0.1 8.9e-19 67.7 0.1 1.5 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 GAP86467.1 - 9.5e-08 31.5 0.3 0.011 14.8 0.0 2.6 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase DAO PF01266.19 GAP86467.1 - 1e-07 31.2 4.4 3e-05 23.1 0.5 2.8 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAP86467.1 - 7.7e-07 29.0 0.2 1.8e-06 27.8 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAP86467.1 - 5.3e-06 25.5 0.0 1.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAP86467.1 - 1.4e-05 24.1 2.0 1.6e-05 23.9 0.6 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 GAP86467.1 - 3e-05 24.0 1.9 0.00016 21.6 1.3 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAP86467.1 - 3.8e-05 24.0 2.1 0.0087 16.4 0.9 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP86467.1 - 0.0003 20.9 0.4 0.0018 18.3 0.3 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAP86467.1 - 0.00043 19.0 1.6 0.15 10.6 0.1 2.2 2 0 0 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.9 GAP86467.1 - 0.0005 18.6 2.0 0.0038 15.7 0.6 2.0 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 GAP86467.1 - 0.00052 18.9 0.7 0.00052 18.9 0.5 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 GAP86467.1 - 0.0081 15.2 1.3 0.012 14.6 0.9 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAP86467.1 - 0.023 13.7 0.3 0.049 12.7 0.2 1.5 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 GAP86467.1 - 0.027 14.1 0.1 0.076 12.6 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 GAP86467.1 - 0.052 13.1 0.2 0.052 13.1 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MIF4G PF02854.14 GAP86468.1 - 2.8e-30 105.2 0.4 1.1e-28 100.1 0.1 2.3 2 0 0 2 2 2 2 MIF4G domain MA3 PF02847.12 GAP86468.1 - 4.3e-19 68.2 0.0 1.3e-18 66.7 0.0 1.8 2 0 0 2 2 2 1 MA3 domain DIOX_N PF14226.1 GAP86469.1 - 7e-16 58.7 0.0 1.3e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAP86469.1 - 2.2e-10 40.6 0.0 5e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AA_permease_2 PF13520.1 GAP86471.1 - 3.7e-51 174.0 47.5 4.6e-51 173.6 32.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAP86471.1 - 7.4e-30 103.7 40.4 1e-29 103.2 28.0 1.1 1 0 0 1 1 1 1 Amino acid permease zf-DHHC PF01529.15 GAP86471.1 - 0.29 10.4 1.8 2.5 7.4 0.0 2.9 2 2 0 2 2 2 0 DHHC palmitoyltransferase Pyr_redox_2 PF07992.9 GAP86472.1 - 9.4e-11 41.9 0.0 1.4e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAP86472.1 - 2.6e-06 26.1 0.0 0.0018 16.7 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 GAP86472.1 - 9.1e-05 22.6 0.0 0.11 12.5 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAP86472.1 - 0.0013 17.6 0.0 0.0023 16.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAP86472.1 - 0.026 13.4 0.0 0.049 12.5 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAP86472.1 - 0.036 14.0 0.0 0.094 12.7 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF3107 PF11305.3 GAP86472.1 - 0.041 13.7 0.0 0.091 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3107) FAD_binding_3 PF01494.14 GAP86472.1 - 0.041 12.9 0.0 0.076 12.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 GAP86472.1 - 0.044 13.5 0.0 3.5 7.3 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 GAP86472.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Methyltransf_23 PF13489.1 GAP86473.1 - 0.068 12.8 0.0 0.2 11.3 0.0 1.7 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 GAP86474.1 - 1.9e-10 41.0 0.0 6.8e-10 39.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP86474.1 - 2.6e-07 30.0 0.0 4.7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 GAP86474.1 - 4.3e-07 30.2 0.0 8.3e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP86474.1 - 2.3e-05 24.1 0.0 3.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP86474.1 - 4e-05 23.2 0.0 7.1e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP86474.1 - 5.4e-05 23.6 0.0 0.00016 22.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain FmrO PF07091.6 GAP86474.1 - 0.00028 19.9 0.0 0.0004 19.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_18 PF12847.2 GAP86474.1 - 0.0027 18.2 0.0 0.012 16.1 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Peptidase_M19 PF01244.16 GAP86475.1 - 2.9e-106 355.0 0.0 3.3e-106 354.8 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) YebO PF13974.1 GAP86475.1 - 0.14 11.9 0.8 22 4.9 0.0 2.5 2 0 0 2 2 2 0 YebO-like protein DPM2 PF07297.7 GAP86477.1 - 4.5e-33 113.3 2.2 5.2e-33 113.1 1.5 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 GAP86477.1 - 0.00011 21.8 1.3 0.00013 21.6 0.9 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.1 GAP86477.1 - 0.0004 20.2 0.3 0.0004 20.2 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) COX14 PF14880.1 GAP86477.1 - 0.012 15.1 3.3 0.038 13.5 0.0 2.2 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF4083 PF13314.1 GAP86477.1 - 0.013 15.3 0.1 0.013 15.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DUF588 PF04535.7 GAP86477.1 - 0.056 13.0 0.6 0.08 12.5 0.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF588) Cation_efflux PF01545.16 GAP86477.1 - 0.067 12.2 0.3 0.075 12.1 0.2 1.0 1 0 0 1 1 1 0 Cation efflux family DiS_P_DiS PF06750.8 GAP86477.1 - 0.073 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain DUF1469 PF07332.6 GAP86477.1 - 0.18 11.5 2.7 0.23 11.1 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Herpes_UL43 PF05072.8 GAP86477.1 - 0.33 9.6 3.3 0.14 10.8 0.6 1.5 2 0 0 2 2 2 0 Herpesvirus UL43 protein DUF543 PF04418.7 GAP86477.1 - 0.91 9.5 3.0 5.7 6.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF543) HAMP PF00672.20 GAP86477.1 - 1.4 9.1 3.4 11 6.2 0.3 2.1 2 0 0 2 2 2 0 HAMP domain TPPK_C PF12555.3 GAP86477.1 - 1.5 8.5 8.0 1.8 8.3 0.5 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal DUF1049 PF06305.6 GAP86477.1 - 3.9 7.0 7.5 0.2 11.1 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1049) ING PF12998.2 GAP86480.1 - 2.6e-05 24.4 0.0 6.3e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding MttA_Hcf106 PF02416.11 GAP86480.1 - 0.068 12.2 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 mttA/Hcf106 family SIMPL PF04402.9 GAP86480.1 - 0.17 11.6 6.6 0.83 9.4 4.6 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Bactofilin PF04519.8 GAP86481.1 - 0.00039 20.3 1.7 0.018 15.0 0.1 2.9 1 1 2 3 3 3 2 Polymer-forming cytoskeletal UBA PF00627.26 GAP86481.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain zf-C2H2 PF00096.21 GAP86483.1 - 0.019 15.3 3.5 0.058 13.7 2.4 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP86483.1 - 0.032 14.5 2.5 0.081 13.2 1.7 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-BED PF02892.10 GAP86483.1 - 0.044 13.5 2.6 0.095 12.4 1.8 1.6 1 0 0 1 1 1 0 BED zinc finger zf-H2C2_2 PF13465.1 GAP86483.1 - 0.067 13.5 1.1 13 6.2 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double domain Sec1 PF00995.18 GAP86484.1 - 2.8e-152 508.2 0.0 3.2e-152 508.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF2404 PF10296.4 GAP86485.1 - 3.7e-08 33.3 0.0 6.5e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Abi PF02517.11 GAP86486.1 - 4.3e-11 42.8 15.3 4.3e-11 42.8 10.6 2.9 2 1 0 2 2 2 1 CAAX protease self-immunity DUF1635 PF07795.6 GAP86486.1 - 0.54 9.6 3.1 0.21 10.9 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) MBOAT PF03062.14 GAP86488.1 - 4e-46 157.6 6.7 4e-46 157.6 4.7 1.6 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MraZ PF02381.13 GAP86488.1 - 0.089 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 MraZ protein DPM3 PF08285.6 GAP86488.1 - 0.25 11.1 0.1 0.25 11.1 0.1 2.6 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DER1 PF04511.10 GAP86490.1 - 2e-49 167.7 4.8 2.3e-49 167.5 3.4 1.0 1 0 0 1 1 1 1 Der1-like family ARD PF03079.9 GAP86491.1 - 1.2e-46 158.5 0.8 1.4e-46 158.3 0.6 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 GAP86491.1 - 2.8e-09 36.3 0.0 5e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 GAP86491.1 - 4.2e-06 26.4 0.0 5.9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 GAP86491.1 - 0.00043 19.7 0.0 0.00058 19.3 0.0 1.2 1 0 0 1 1 1 1 Cupin adh_short PF00106.20 GAP86492.1 - 3.9e-18 65.9 0.0 6e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP86492.1 - 1.4e-09 37.8 0.0 2.8e-09 36.8 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 GAP86492.1 - 1.1e-05 24.9 0.0 2.2e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAP86492.1 - 0.02 14.8 0.0 0.036 14.0 0.0 1.6 1 1 0 1 1 1 0 NADH(P)-binding RmlD_sub_bind PF04321.12 GAP86492.1 - 0.033 13.0 0.0 0.065 12.1 0.0 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 GAP86492.1 - 0.092 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family UAA PF08449.6 GAP86493.1 - 7.2e-11 41.5 17.1 9e-11 41.2 11.9 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 GAP86493.1 - 1.3e-07 31.4 6.2 1.3e-07 31.4 4.3 2.6 2 1 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 GAP86493.1 - 0.0026 17.7 29.1 0.0056 16.7 6.2 2.2 2 0 0 2 2 2 2 EamA-like transporter family Peptidase_A24 PF01478.13 GAP86493.1 - 0.039 14.1 0.1 0.039 14.1 0.1 3.5 2 2 1 3 3 3 0 Type IV leader peptidase family NnrS PF05940.7 GAP86493.1 - 0.1 11.4 13.3 0.42 9.4 5.9 2.2 2 0 0 2 2 2 0 NnrS protein Histone PF00125.19 GAP86494.1 - 6.7e-30 103.0 0.3 8.8e-30 102.6 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 GAP86494.1 - 0.00034 20.7 0.1 0.00049 20.2 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 GAP86494.1 - 0.01 15.8 0.1 0.017 15.1 0.1 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone FUN14 PF04930.10 GAP86495.1 - 6.2 7.1 9.7 0.081 13.2 1.5 1.7 2 0 0 2 2 2 0 FUN14 family Peptidase_M24 PF00557.19 GAP86496.1 - 7.3e-43 146.5 0.0 1.1e-42 146.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 GAP86496.1 - 1.4e-27 96.7 0.0 8.9e-23 81.2 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain DUF4045 PF13254.1 GAP86497.1 - 0.0042 16.4 0.0 0.0064 15.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4045) Ribosomal_L32e PF01655.13 GAP86499.1 - 2.1e-49 166.1 1.9 2.5e-49 165.9 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Gp_UL130 PF11668.3 GAP86499.1 - 0.074 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 HCMV glycoprotein pUL130 DnaJ PF00226.26 GAP86500.1 - 1.2e-25 89.0 1.9 2.1e-25 88.2 1.3 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 GAP86500.1 - 5.6e-21 74.2 0.8 2.8e-18 65.5 0.0 3.3 3 1 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 GAP86500.1 - 1e-13 51.1 17.7 1.8e-13 50.3 12.2 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 GAP86500.1 - 0.018 14.7 6.1 0.49 10.0 0.5 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 GAP86500.1 - 0.069 13.5 3.8 0.13 12.6 2.6 1.5 1 0 0 1 1 1 0 Cytochrome c3 Fork_head_N PF08430.7 GAP86500.1 - 0.14 12.5 5.4 0.24 11.7 3.7 1.3 1 0 0 1 1 1 0 Forkhead N-terminal region DUF1356 PF07092.7 GAP86500.1 - 0.29 10.2 4.1 0.5 9.5 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) tRNA-synt_1c PF00749.16 GAP86501.1 - 1.5e-96 322.7 0.0 2.1e-96 322.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain zf-Nse PF11789.3 GAP86501.1 - 0.15 11.5 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit JAB PF01398.16 GAP86502.1 - 7.5e-30 103.0 0.4 2.1e-29 101.5 0.1 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 GAP86502.1 - 1.1e-06 28.1 0.0 2.1e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 GAP86502.1 - 0.059 12.8 0.0 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0172) Ribosomal_S10 PF00338.17 GAP86503.1 - 8e-23 80.1 0.0 1.3e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e FAM75 PF14650.1 GAP86503.1 - 0.049 13.0 0.1 0.062 12.6 0.1 1.2 1 0 0 1 1 1 0 FAM75 family tRNA-synt_1b PF00579.20 GAP86504.1 - 1e-68 231.6 0.0 1.3e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) NYAP_C PF15452.1 GAP86504.1 - 0.45 9.4 2.4 1 8.2 1.7 1.5 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Pyr_redox_2 PF07992.9 GAP86505.1 - 3e-22 79.4 0.0 9.4e-22 77.8 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAP86505.1 - 2.6e-12 46.9 0.0 7.3e-12 45.5 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP86505.1 - 7.6e-06 26.1 0.0 0.0086 16.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAP86506.1 - 6.3e-76 255.7 0.2 8.2e-76 255.3 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 GAP86506.1 - 6.4e-37 126.7 0.0 1.1e-36 126.0 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.12 GAP86506.1 - 0.00024 20.2 0.1 0.00038 19.6 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 GAP86506.1 - 0.00028 20.1 0.3 0.00039 19.6 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAP86506.1 - 0.00066 18.6 0.3 0.0014 17.6 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAP86506.1 - 0.0009 18.2 0.2 0.0009 18.2 0.1 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAP86506.1 - 0.0016 18.3 0.3 0.006 16.5 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAP86506.1 - 0.025 14.4 0.5 0.067 13.0 0.3 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP86506.1 - 0.054 13.5 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAP86506.1 - 0.07 11.9 0.1 0.088 11.6 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.22 GAP86506.1 - 0.086 13.2 0.3 0.23 11.8 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAP86506.1 - 0.11 10.9 0.1 0.18 10.2 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein AAA_5 PF07728.9 GAP86507.1 - 4.8e-125 411.8 0.1 1.3e-21 76.8 0.0 10.0 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA PF00004.24 GAP86507.1 - 2.6e-33 115.0 0.0 0.0001 22.5 0.0 7.0 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 GAP86507.1 - 3.6e-31 107.4 0.0 7.8e-10 38.4 0.0 7.4 8 0 0 8 8 8 3 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 GAP86507.1 - 1.2e-27 97.1 0.0 7.4e-05 23.5 0.0 7.5 6 0 0 6 6 6 5 AAA domain AAA_33 PF13671.1 GAP86507.1 - 7.3e-27 94.0 0.0 0.00053 19.8 0.0 7.1 6 0 0 6 6 6 6 AAA domain AAA_16 PF13191.1 GAP86507.1 - 1.7e-25 90.0 14.7 0.00069 19.6 0.0 8.3 8 0 0 8 8 6 5 AAA ATPase domain AAA_22 PF13401.1 GAP86507.1 - 5.4e-24 84.8 1.8 0.024 14.7 0.0 8.3 7 1 0 7 7 6 6 AAA domain AAA_14 PF13173.1 GAP86507.1 - 2.8e-23 82.2 0.0 0.0002 21.2 0.0 8.4 7 1 1 8 8 7 4 AAA domain AAA_18 PF13238.1 GAP86507.1 - 1.8e-22 80.0 3.5 0.0044 17.3 0.0 8.4 8 0 0 8 8 7 4 AAA domain Sigma54_activ_2 PF14532.1 GAP86507.1 - 3.2e-21 75.8 0.4 4.4e-05 23.5 0.0 7.8 7 0 0 7 7 7 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 GAP86507.1 - 2.9e-17 62.6 0.0 0.015 14.7 0.0 6.5 6 0 0 6 6 6 3 Sigma-54 interaction domain Zeta_toxin PF06414.7 GAP86507.1 - 2.5e-16 59.3 0.1 0.051 12.6 0.0 6.8 6 0 0 6 6 6 3 Zeta toxin RNA_helicase PF00910.17 GAP86507.1 - 4.1e-16 59.0 0.9 0.13 12.3 0.0 6.8 6 0 0 6 6 6 3 RNA helicase NACHT PF05729.7 GAP86507.1 - 4.7e-15 55.6 5.3 0.04 13.5 0.0 6.7 6 0 0 6 6 6 5 NACHT domain T2SE PF00437.15 GAP86507.1 - 7.3e-15 54.5 1.6 0.046 12.6 0.0 6.2 6 0 0 6 6 6 4 Type II/IV secretion system protein AAA_28 PF13521.1 GAP86507.1 - 1e-14 54.7 1.0 0.14 12.0 0.0 7.1 6 0 0 6 6 6 2 AAA domain UPF0079 PF02367.12 GAP86507.1 - 2e-14 53.2 2.6 0.014 14.9 0.0 6.3 6 0 0 6 6 6 3 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 GAP86507.1 - 5.2e-14 52.7 9.0 0.0084 16.4 0.0 7.2 7 0 0 7 7 6 3 ABC transporter AAA_19 PF13245.1 GAP86507.1 - 5.8e-14 51.6 6.8 0.014 15.1 0.0 6.6 6 0 0 6 6 6 3 Part of AAA domain DUF258 PF03193.11 GAP86507.1 - 2.7e-13 49.4 4.1 0.15 11.2 0.0 6.4 6 0 0 6 6 6 4 Protein of unknown function, DUF258 RuvB_N PF05496.7 GAP86507.1 - 4.1e-13 48.9 2.8 0.00034 19.7 0.0 6.5 7 0 0 7 7 7 3 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 GAP86507.1 - 5.7e-13 48.5 2.5 2.1 7.4 0.0 8.6 8 0 0 8 8 8 1 Magnesium chelatase, subunit ChlI MobB PF03205.9 GAP86507.1 - 4.2e-12 45.9 0.6 0.77 9.4 0.0 6.4 6 0 0 6 6 6 2 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 GAP86507.1 - 1.7e-11 44.3 0.0 0.0022 17.7 0.0 6.5 6 0 0 6 6 6 1 Archaeal ATPase AAA_25 PF13481.1 GAP86507.1 - 5.1e-11 42.3 0.8 0.94 8.8 0.0 5.7 5 0 0 5 5 5 2 AAA domain Viral_helicase1 PF01443.13 GAP86507.1 - 6.2e-10 39.0 0.0 0.054 12.9 0.0 6.0 6 0 0 6 6 6 2 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.4 GAP86507.1 - 1.2e-09 37.7 0.9 0.035 13.5 0.0 5.9 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 GAP86507.1 - 7e-09 35.0 0.1 2.9 7.5 0.0 6.2 6 0 0 6 6 6 1 P-loop containing region of AAA domain IstB_IS21 PF01695.12 GAP86507.1 - 7.7e-09 35.2 0.3 2.6 7.4 0.0 5.9 6 0 0 6 6 5 1 IstB-like ATP binding protein SRP54 PF00448.17 GAP86507.1 - 1.3e-08 34.5 1.1 0.75 9.2 0.0 5.5 6 0 0 6 6 5 2 SRP54-type protein, GTPase domain Miro PF08477.8 GAP86507.1 - 1.5e-08 35.1 6.7 6.8 7.2 0.0 6.9 7 0 0 7 7 6 0 Miro-like protein Rad17 PF03215.10 GAP86507.1 - 6.8e-08 31.6 3.3 0.22 10.1 0.0 5.7 6 0 0 6 6 6 1 Rad17 cell cycle checkpoint protein MMR_HSR1 PF01926.18 GAP86507.1 - 2.6e-07 30.6 0.3 7.8 6.4 0.0 7.0 6 0 0 6 6 6 0 50S ribosome-binding GTPase cobW PF02492.14 GAP86507.1 - 9e-07 28.5 4.7 3.8 6.9 0.0 6.1 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.8 GAP86507.1 - 9e-07 28.0 2.2 3.8 6.3 0.0 5.8 6 0 0 6 6 6 0 Protein of unknown function (DUF815) NTPase_1 PF03266.10 GAP86507.1 - 1.5e-06 27.9 5.2 0.92 9.1 0.0 5.8 6 0 0 6 6 5 2 NTPase AAA_24 PF13479.1 GAP86507.1 - 1.5e-05 24.7 1.0 8.4 5.9 0.0 6.0 6 0 0 6 6 6 0 AAA domain AAA_7 PF12775.2 GAP86507.1 - 3.1e-05 23.1 0.6 6.8 5.6 0.0 4.6 5 0 0 5 5 4 0 P-loop containing dynein motor region D3 TIP49 PF06068.8 GAP86507.1 - 0.00014 20.7 0.2 12 4.4 0.0 4.7 5 0 0 5 5 5 0 TIP49 C-terminus NB-ARC PF00931.17 GAP86507.1 - 0.00031 19.7 5.5 11 4.8 0.0 5.6 6 0 0 6 6 5 0 NB-ARC domain KTI12 PF08433.5 GAP86507.1 - 0.00031 20.0 0.1 0.053 12.7 0.0 4.0 5 0 0 5 5 5 1 Chromatin associated protein KTI12 ATP-synt_ab PF00006.20 GAP86507.1 - 0.00033 20.2 0.0 4.4 6.7 0.0 4.9 6 0 0 6 6 6 0 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 GAP86507.1 - 0.00054 19.4 2.0 16 4.8 0.0 5.0 5 0 0 5 5 4 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 GAP86507.1 - 0.0029 17.1 5.8 9.4 5.6 0.1 5.4 6 0 0 6 6 5 0 Conserved hypothetical ATP binding protein KaiC PF06745.8 GAP86507.1 - 0.0065 15.6 0.5 9.5 5.2 0.0 4.6 5 0 0 5 5 4 0 KaiC SKI PF01202.17 GAP86507.1 - 0.0083 16.0 1.2 21 4.9 0.0 4.5 4 0 0 4 4 4 0 Shikimate kinase ArgK PF03308.11 GAP86507.1 - 0.0093 14.7 1.8 13 4.4 0.1 3.7 3 0 0 3 3 3 0 ArgK protein AAA_6 PF12774.2 GAP86507.1 - 0.043 13.3 0.0 12 5.3 0.0 4.5 6 0 0 6 6 5 0 Hydrolytic ATP binding site of dynein motor region D1 PhoH PF02562.11 GAP86507.1 - 0.069 12.3 0.1 6.2 5.9 0.0 3.6 4 0 0 4 4 4 0 PhoH-like protein Hpr_kinase_C PF07475.7 GAP86507.1 - 1.7 7.9 4.2 1.2 8.4 0.1 2.8 4 0 0 4 4 3 0 HPr Serine kinase C-terminal domain Ribosomal_L12 PF00542.14 GAP86508.1 - 1.7e-19 69.5 6.4 1.4e-18 66.6 3.7 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain ApbA_C PF08546.6 GAP86509.1 - 4.4e-24 84.8 0.0 7.2e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 GAP86509.1 - 1.4e-23 83.0 0.0 1.9e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 GAP86509.1 - 0.015 14.2 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Zip PF02535.17 GAP86510.1 - 3.2e-38 131.5 11.1 5.4e-36 124.2 7.7 2.8 1 1 0 1 1 1 1 ZIP Zinc transporter DUF805 PF05656.9 GAP86510.1 - 8.1 6.2 8.7 0.91 9.3 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF805) Hat1_N PF10394.4 GAP86511.1 - 9.1e-39 133.1 0.0 1.8e-38 132.1 0.0 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.1 GAP86511.1 - 0.015 15.3 0.0 0.038 14.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAP86511.1 - 0.026 14.5 0.0 0.062 13.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family MOZ_SAS PF01853.13 GAP86511.1 - 0.053 12.7 0.0 0.094 11.9 0.0 1.4 1 0 0 1 1 1 0 MOZ/SAS family Acetyltransf_7 PF13508.1 GAP86511.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain P5CR_dimer PF14748.1 GAP86512.1 - 6.3e-32 109.7 2.1 1e-31 109.0 1.4 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 GAP86512.1 - 5.7e-11 42.7 0.4 6.2e-08 32.9 0.0 2.4 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent DUF1899 PF08953.6 GAP86512.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1899) Thioredoxin_3 PF13192.1 GAP86512.1 - 0.12 12.2 0.7 0.28 11.0 0.1 1.9 2 0 0 2 2 2 0 Thioredoxin domain CTK3 PF12243.3 GAP86513.1 - 1.3e-58 196.5 1.2 1.7e-58 196.1 0.8 1.1 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 GAP86513.1 - 3e-17 62.4 0.8 3e-17 62.4 0.6 1.7 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus MAM33 PF02330.11 GAP86513.1 - 0.0032 17.2 0.6 0.0049 16.6 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial glycoprotein WD40 PF00400.27 GAP86514.1 - 1.1e-50 167.7 22.2 6.4e-11 41.7 0.4 7.3 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 GAP86514.1 - 8.5e-13 47.8 1.5 1.7e-12 46.8 1.0 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 GAP86514.1 - 1.7e-08 33.0 12.6 0.011 13.8 2.5 6.0 1 1 3 4 4 4 4 Nucleoporin Nup120/160 F-box PF00646.28 GAP86514.1 - 3.2e-07 29.8 2.4 6.7e-07 28.8 1.7 1.6 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 GAP86514.1 - 0.003 17.0 3.1 0.011 15.1 0.5 2.3 2 0 0 2 2 2 1 PQQ-like domain PQQ_3 PF13570.1 GAP86514.1 - 0.011 15.9 4.6 10 6.5 0.1 4.9 5 0 0 5 5 5 0 PQQ-like domain BBS2_Mid PF14783.1 GAP86514.1 - 0.013 15.2 0.1 2.6 7.8 0.0 3.4 4 1 1 5 5 5 0 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 GAP86514.1 - 0.06 12.0 0.1 0.29 9.8 0.0 2.1 1 1 1 2 2 2 0 Nup133 N terminal like DUF2178 PF09946.4 GAP86514.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) U3_snoRNA_assoc PF08297.6 GAP86516.1 - 4.2e-06 26.9 0.0 4.2e-06 26.9 0.0 4.8 3 2 0 3 3 3 1 U3 snoRNA associated Gar1 PF04410.9 GAP86516.1 - 0.0057 16.1 1.8 0.0057 16.1 1.2 2.7 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region MFS_1 PF07690.11 GAP86517.1 - 7.7e-20 70.9 54.7 1.6e-19 69.8 34.7 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily PH_10 PF15411.1 GAP86518.1 - 2.2e-27 95.5 0.2 3.8e-27 94.7 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 GAP86518.1 - 1.2e-10 41.2 0.0 3.8e-10 39.6 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 GAP86518.1 - 7.4e-09 35.5 0.3 1.4e-08 34.7 0.2 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 GAP86518.1 - 3.6e-07 29.9 5.8 6.8e-07 29.0 4.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAP86518.1 - 0.006 16.6 1.3 0.013 15.6 0.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 GAP86518.1 - 0.0068 16.1 5.6 0.012 15.3 3.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C4_Topoisom PF01396.14 GAP86518.1 - 0.053 13.0 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger zf-C3HC4 PF00097.20 GAP86518.1 - 0.099 12.3 5.5 0.21 11.2 3.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAP86518.1 - 0.12 12.3 5.1 0.22 11.5 3.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 GAP86518.1 - 0.7 9.9 4.5 1.3 9.0 3.1 1.4 1 0 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.1 GAP86518.1 - 0.99 9.1 2.5 2.7 7.7 0.2 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 FMO-like PF00743.14 GAP86519.1 - 2.6e-45 154.6 0.0 9.7e-23 80.1 0.0 3.2 2 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 GAP86519.1 - 3.7e-22 79.4 0.0 2.3e-20 73.5 0.0 3.0 3 1 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAP86519.1 - 3e-10 40.3 0.0 0.0082 16.0 0.5 3.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP86519.1 - 4e-10 39.5 0.6 3.4e-09 36.5 0.0 2.6 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAP86519.1 - 1.4e-07 30.7 6.0 1.3e-05 24.2 1.8 3.1 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAP86519.1 - 2.6e-07 30.5 2.9 5.8e-05 22.9 0.8 3.5 3 1 0 3 3 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 GAP86519.1 - 4.9e-07 28.9 0.8 0.00012 21.1 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 GAP86519.1 - 6.4e-06 25.5 0.2 0.0022 17.1 0.0 2.7 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 GAP86519.1 - 1.7e-05 25.1 0.9 0.0014 18.9 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAP86519.1 - 9.9e-05 21.5 1.0 0.00052 19.1 0.2 2.3 2 0 0 2 2 2 1 Thi4 family Shikimate_DH PF01488.15 GAP86519.1 - 0.00026 21.1 0.2 0.2 11.7 0.1 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 GAP86519.1 - 0.00082 18.5 0.3 0.0014 17.7 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAP86519.1 - 0.0014 17.5 0.5 0.0059 15.5 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 GAP86519.1 - 0.0018 16.8 0.6 0.0018 16.8 0.4 1.8 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 GAP86519.1 - 0.0082 15.0 1.6 0.016 14.1 0.2 2.1 3 0 0 3 3 3 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 GAP86519.1 - 0.012 15.2 0.6 0.028 14.0 0.4 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 GAP86519.1 - 0.013 14.5 0.7 0.026 13.5 0.2 1.6 2 0 0 2 2 2 0 FAD binding domain NAD_binding_2 PF03446.10 GAP86519.1 - 0.018 14.9 0.1 0.051 13.4 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.1 GAP86519.1 - 0.046 13.9 0.1 2.7 8.2 0.0 2.9 2 1 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_10 PF13460.1 GAP86519.1 - 0.068 13.1 3.1 1.4 8.9 0.2 3.3 3 1 1 4 4 4 0 NADH(P)-binding 2-Hacid_dh_C PF02826.14 GAP86519.1 - 0.089 11.9 0.3 0.53 9.4 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 GAP86519.1 - 0.17 11.2 0.2 0.3 10.4 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 GAP86519.1 - 0.25 10.7 2.1 1.1 8.7 0.7 2.4 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Cpn60_TCP1 PF00118.19 GAP86520.1 - 3.8e-136 454.5 5.4 4.4e-136 454.3 3.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2204 PF09970.4 GAP86520.1 - 0.0017 17.8 0.6 0.67 9.4 0.0 3.3 3 0 0 3 3 3 1 Nucleotidyl transferase of unknown function (DUF2204) EAL PF00563.15 GAP86520.1 - 0.0075 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 EAL domain ACT PF01842.20 GAP86520.1 - 0.043 13.3 0.1 0.42 10.1 0.0 2.6 2 0 0 2 2 2 0 ACT domain HAD PF12710.2 GAP86520.1 - 0.053 13.6 0.2 0.14 12.2 0.1 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HMG_box PF00505.14 GAP86521.1 - 2.4e-09 37.3 4.9 4e-09 36.6 2.4 2.2 1 1 1 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 GAP86521.1 - 1.3e-05 25.4 1.1 1.3e-05 25.4 0.7 2.6 2 1 1 3 3 3 1 HMG-box domain bZIP_1 PF00170.16 GAP86521.1 - 0.0011 18.8 1.9 0.0011 18.8 1.3 2.8 3 0 0 3 3 3 1 bZIP transcription factor PilJ PF13675.1 GAP86521.1 - 0.06 13.6 2.0 0.19 12.0 0.3 2.2 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term MbeD_MobD PF04899.7 GAP86521.1 - 0.12 12.2 5.1 2.2 8.2 1.0 2.3 2 0 0 2 2 2 0 MbeD/MobD like DUF972 PF06156.8 GAP86521.1 - 0.38 11.1 2.7 0.4 11.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Atg14 PF10186.4 GAP86521.1 - 2.6 6.9 11.5 0.27 10.1 3.2 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF155 PF02582.9 GAP86522.1 - 1.8e-54 184.2 0.2 2.6e-54 183.7 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Saccharop_dh PF03435.13 GAP86523.1 - 1.1e-15 57.5 0.1 1.7e-15 56.9 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 GAP86523.1 - 9.1e-06 25.9 0.0 2.6e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain PHD PF00628.24 GAP86524.1 - 5e-10 38.9 6.4 5e-10 38.9 4.4 2.8 2 1 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 GAP86524.1 - 1.3e-08 34.5 0.6 1.3e-08 34.5 0.4 4.2 3 1 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 GAP86524.1 - 4.9e-07 29.7 0.2 4.9e-07 29.7 0.2 3.1 3 0 0 3 3 3 1 RING-H2 zinc finger zf-RING_5 PF14634.1 GAP86524.1 - 1e-05 25.1 0.6 1e-05 25.1 0.4 3.9 4 1 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 GAP86524.1 - 1.6e-05 24.4 0.5 1.6e-05 24.4 0.4 3.9 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAP86524.1 - 4.3e-05 23.4 0.7 4.3e-05 23.4 0.5 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAP86524.1 - 4.5e-05 23.2 0.4 4.5e-05 23.2 0.3 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 GAP86524.1 - 9.5e-05 21.9 0.6 9.5e-05 21.9 0.4 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 GAP86524.1 - 0.00074 19.1 3.0 0.00074 19.1 2.1 3.1 3 1 0 3 3 2 1 Prokaryotic RING finger family 1 PHD_2 PF13831.1 GAP86524.1 - 0.0015 17.7 3.2 0.0015 17.7 2.2 2.3 2 0 0 2 2 2 1 PHD-finger Rtf2 PF04641.7 GAP86524.1 - 0.0082 15.3 0.2 0.023 13.9 0.1 1.8 1 1 0 1 1 1 1 Rtf2 RING-finger DZR PF12773.2 GAP86524.1 - 0.079 12.7 8.0 0.72 9.7 2.2 2.8 2 1 0 2 2 2 0 Double zinc ribbon FANCL_C PF11793.3 GAP86524.1 - 1.1 9.2 8.4 0.6 10.1 0.3 2.7 2 0 0 2 2 2 0 FANCL C-terminal domain DnaJ PF00226.26 GAP86525.1 - 2.8e-13 49.4 0.1 6.3e-13 48.2 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain FlxA PF14282.1 GAP86525.1 - 0.87 9.5 0.0 0.87 9.5 0.0 2.6 3 0 0 3 3 3 0 FlxA-like protein Pkinase PF00069.20 GAP86526.1 - 6.1e-59 199.2 0.0 7.4e-59 199.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP86526.1 - 9.4e-35 119.9 0.0 1.3e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP86526.1 - 2.3e-07 30.1 0.0 3.4e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 GAP86527.1 - 1.2e-07 31.2 0.0 1.9e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 GAP86527.1 - 0.027 14.2 0.0 0.074 12.7 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 GAP86527.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DEAD PF00270.24 GAP86528.1 - 9.8e-40 135.7 0.4 9.5e-38 129.3 0.1 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP86528.1 - 1e-26 92.6 0.1 2.3e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 GAP86528.1 - 0.00077 18.3 0.0 0.0021 16.9 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.10 GAP86528.1 - 0.023 14.5 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SDA1 PF05285.7 GAP86529.1 - 7.4 5.7 12.0 13 4.9 8.3 1.4 1 0 0 1 1 1 0 SDA1 GCV_T PF01571.16 GAP86531.1 - 3.5e-13 49.4 0.0 1.1e-12 47.8 0.0 1.8 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 GAP86531.1 - 0.013 15.4 0.0 0.04 13.9 0.0 1.9 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain GTP_EFTU PF00009.22 GAP86532.1 - 2.1e-52 177.2 0.0 3.5e-52 176.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 GAP86532.1 - 8.1e-16 57.6 0.0 2.2e-15 56.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 GAP86532.1 - 3.5e-09 36.6 0.0 9.3e-09 35.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 GAP86532.1 - 6.8e-08 32.2 0.0 1.4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 GAP86532.1 - 2.8e-05 23.6 0.2 0.022 14.3 0.0 3.1 3 1 0 3 3 3 2 Elongation factor G, domain IV MMR_HSR1 PF01926.18 GAP86532.1 - 0.0094 15.8 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SET PF00856.23 GAP86532.1 - 0.2 11.9 0.0 0.57 10.4 0.0 1.8 1 0 0 1 1 1 0 SET domain Paf67 PF10255.4 GAP86533.1 - 7.9e-153 509.0 0.3 9.4e-153 508.8 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 Usp PF00582.21 GAP86535.1 - 3.5e-15 56.4 0.1 1.3e-14 54.5 0.0 2.0 2 0 0 2 2 2 1 Universal stress protein family Amidohydro_2 PF04909.9 GAP86536.1 - 1.9e-38 132.6 1.1 6.4e-38 130.8 0.7 1.8 1 1 0 1 1 1 1 Amidohydrolase DIOX_N PF14226.1 GAP86537.1 - 1.4e-21 77.1 0.0 2.3e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAP86537.1 - 3.7e-17 62.4 0.0 6.3e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GBP_repeat PF02526.9 GAP86537.1 - 0.095 12.1 1.6 2.4 7.6 0.0 2.9 3 0 0 3 3 3 0 Glycophorin-binding protein PGAP1 PF07819.8 GAP86538.1 - 0.00035 20.2 0.0 0.00062 19.4 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 GAP86538.1 - 0.0026 17.5 0.8 0.0076 16.0 0.6 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP86538.1 - 0.0081 16.0 0.9 0.014 15.3 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 GAP86538.1 - 0.11 12.7 0.0 0.38 10.9 0.0 1.9 2 0 0 2 2 2 0 Thioesterase domain PTPLA PF04387.9 GAP86539.1 - 1.7e-50 170.6 6.5 2.5e-50 170.1 4.5 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Ribosomal_S14 PF00253.16 GAP86540.1 - 0.009 15.3 0.2 0.04 13.2 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e IL7 PF01415.11 GAP86541.1 - 0.028 14.0 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 Interleukin 7/9 family WD40 PF00400.27 GAP86543.1 - 8.9e-43 142.6 18.1 9.7e-09 34.7 0.0 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 GAP86543.1 - 3.3e-09 36.3 0.2 3.3e-09 36.3 0.2 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 GAP86543.1 - 1.1e-06 28.1 0.0 2.3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 GAP86543.1 - 2e-06 26.2 0.6 0.0035 15.5 0.0 3.8 1 1 2 3 3 3 2 Nucleoporin Nup120/160 FlaG PF03646.10 GAP86543.1 - 0.0085 16.2 0.0 0.23 11.6 0.0 2.9 3 0 0 3 3 3 1 FlaG protein Zn_clus PF00172.13 GAP86544.1 - 8.4e-05 22.3 14.1 0.00015 21.6 9.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 GAP86546.1 - 8e-08 32.0 5.7 1.3e-07 31.4 4.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAP86546.1 - 1.8e-07 30.1 0.4 3.9e-07 29.0 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 GAP86547.1 - 9.2e-06 25.6 5.4 0.0092 16.2 0.1 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 GAP86547.1 - 0.013 15.7 2.1 1 9.8 0.0 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type Delta_lysin PF05372.6 GAP86548.1 - 0.78 9.1 3.7 0.35 10.2 0.4 2.0 2 0 0 2 2 2 0 Delta lysin family Ribosomal_L1 PF00687.16 GAP86549.1 - 1.7e-53 181.1 0.4 2.1e-53 180.9 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DEK_C PF08766.6 GAP86549.1 - 0.78 9.5 0.1 0.78 9.5 0.1 2.5 3 0 0 3 3 3 0 DEK C terminal domain NUDIX PF00293.23 GAP86550.1 - 2.5e-17 62.7 0.0 8.6e-17 61.0 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain NUDIX-like PF09296.6 GAP86550.1 - 3.1e-13 49.9 0.0 1.7e-12 47.5 0.0 2.1 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 GAP86550.1 - 2.6e-05 23.6 0.5 4.8e-05 22.7 0.3 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain PQ-loop PF04193.9 GAP86551.1 - 7.9e-40 134.2 8.8 1.5e-19 69.2 1.0 2.5 2 0 0 2 2 2 2 PQ loop repeat Glyco_hydro_88 PF07470.8 GAP86552.1 - 8.1e-61 205.9 7.0 9.8e-61 205.6 4.8 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 FAD_binding_7 PF03441.9 GAP86554.1 - 2.4e-86 289.3 0.2 3.4e-86 288.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 GAP86554.1 - 3.9e-36 124.2 0.0 9.5e-36 123.0 0.0 1.7 1 0 0 1 1 1 1 DNA photolyase Inositol_P PF00459.20 GAP86554.1 - 9.5e-35 120.1 0.0 2e-34 119.1 0.0 1.5 1 0 0 1 1 1 1 Inositol monophosphatase family DUF543 PF04418.7 GAP86555.1 - 3.7e-29 100.4 0.0 4.3e-29 100.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Urb2 PF10441.4 GAP86556.1 - 2.5e-48 164.6 0.0 3.5e-47 160.8 0.0 2.5 2 0 0 2 2 2 1 Urb2/Npa2 family NRDE-2 PF08424.5 GAP86557.1 - 8.5e-85 284.4 0.2 6.4e-84 281.5 0.2 2.0 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 GAP86557.1 - 0.00043 20.6 9.4 1.2 9.9 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAP86557.1 - 0.018 15.3 4.3 2.7 8.3 0.1 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAP86557.1 - 0.053 14.2 18.6 0.63 10.7 0.0 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat Voltage_CLC PF00654.15 GAP86558.1 - 4.1e-93 312.2 21.0 4.1e-93 312.2 14.5 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel TAT_signal PF10518.4 GAP86558.1 - 7.1 6.9 16.4 0.045 13.7 1.0 4.0 3 0 0 3 3 3 0 TAT (twin-arginine translocation) pathway signal sequence DUF924 PF06041.6 GAP86560.1 - 1.9e-41 141.9 0.0 2.2e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) TPR_11 PF13414.1 GAP86561.1 - 7.3e-16 57.5 27.2 0.0015 18.1 3.5 6.8 6 0 0 6 6 6 5 TPR repeat TPR_19 PF14559.1 GAP86561.1 - 6.4e-10 39.2 17.8 0.054 13.8 0.0 8.0 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAP86561.1 - 1.8e-08 33.6 36.1 0.021 14.7 0.1 9.3 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAP86561.1 - 9.7e-08 31.9 29.3 0.028 15.0 0.2 9.9 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_1 PF00515.23 GAP86561.1 - 4.4e-05 22.8 23.8 0.099 12.2 0.1 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAP86561.1 - 0.00011 22.1 14.4 2 8.8 0.0 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAP86561.1 - 0.00015 22.3 40.9 0.48 11.1 4.8 8.6 8 1 2 10 10 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAP86561.1 - 0.00023 21.0 27.0 0.025 14.4 2.9 7.1 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAP86561.1 - 0.00034 20.1 10.5 0.025 14.3 0.1 5.8 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAP86561.1 - 0.0095 16.3 11.5 0.34 11.4 0.0 5.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAP86561.1 - 0.019 14.7 7.8 0.44 10.4 0.1 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat Apc3 PF12895.2 GAP86561.1 - 0.021 14.9 0.5 0.021 14.9 0.3 5.4 6 0 0 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 PPTA PF01239.17 GAP86561.1 - 0.067 12.5 0.1 0.21 10.9 0.1 1.9 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat Alkyl_sulf_dimr PF14863.1 GAP86561.1 - 0.63 10.2 7.6 4.7 7.4 0.5 3.2 4 0 0 4 4 3 0 Alkyl sulfatase dimerisation TPR_20 PF14561.1 GAP86561.1 - 3.3 7.8 14.8 18 5.5 2.5 4.3 5 0 0 5 5 3 0 Tetratricopeptide repeat SAM_2 PF07647.12 GAP86562.1 - 9.4e-11 41.3 0.1 1.7e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 GAP86562.1 - 1.1e-06 28.6 0.1 2.1e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Mito_carr PF00153.22 GAP86563.1 - 7.4e-58 192.2 2.8 2.5e-20 71.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C2 PF00648.16 GAP86564.1 - 6.4e-22 77.9 0.0 1.1e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 GAP86564.1 - 3.8e-15 55.8 0.1 1.4e-12 47.4 0.0 3.6 2 2 1 3 3 3 1 Calpain large subunit, domain III MIT PF04212.13 GAP86564.1 - 0.00086 19.1 1.7 0.0014 18.4 1.2 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain zf-C2H2_4 PF13894.1 GAP86565.1 - 1.5e-07 31.2 12.3 0.00063 19.8 1.9 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 GAP86565.1 - 3.6e-06 26.9 12.3 0.0049 17.1 1.2 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAP86565.1 - 0.00086 19.4 9.1 0.9 9.9 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-Di19 PF05605.7 GAP86565.1 - 0.17 12.0 6.4 0.22 11.6 0.7 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding ADH_N PF08240.7 GAP86567.1 - 1.9e-27 95.1 0.5 3.4e-27 94.3 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAP86567.1 - 1.1e-17 63.8 0.0 2.1e-17 62.8 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 GAP86567.1 - 0.044 13.4 0.1 0.098 12.3 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Sen15 PF09631.5 GAP86568.1 - 9e-28 96.4 0.0 1.1e-27 96.2 0.0 1.0 1 0 0 1 1 1 1 Sen15 protein DUF2985 PF11204.3 GAP86569.1 - 1.6e-30 104.6 0.7 3.1e-30 103.7 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Na_H_Exchanger PF00999.16 GAP86569.1 - 0.27 9.7 5.3 0.13 10.7 0.3 2.1 2 0 0 2 2 2 0 Sodium/hydrogen exchanger family Vma12 PF11712.3 GAP86569.1 - 0.77 9.4 7.9 0.95 9.1 0.3 2.8 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase AAA PF00004.24 GAP86570.1 - 7.3e-07 29.4 0.0 1.4e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAP86570.1 - 0.00086 19.0 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 GAP86570.1 - 0.0029 17.7 0.0 0.0065 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAP86570.1 - 0.0033 18.2 0.0 0.036 14.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAP86570.1 - 0.0067 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 GAP86570.1 - 0.07 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAP86570.1 - 0.079 13.2 0.0 0.3 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 GAP86570.1 - 0.098 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 GAP86570.1 - 0.1 12.3 0.2 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain MCM PF00493.18 GAP86570.1 - 0.16 10.7 0.0 0.3 9.8 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family DUF1664 PF07889.7 GAP86571.1 - 0.015 15.0 0.5 0.033 13.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.1 GAP86571.1 - 0.017 15.1 0.1 0.044 13.8 0.1 1.7 1 0 0 1 1 1 0 Syntaxin-like protein Tho2 PF11262.3 GAP86571.1 - 0.5 9.3 3.0 0.37 9.7 0.8 1.7 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 ArabFuran-catal PF09206.6 GAP86572.1 - 1.5e-139 464.4 19.0 1.9e-139 464.1 13.2 1.1 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.8 GAP86572.1 - 5.6e-57 191.4 0.2 1e-56 190.5 0.1 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) Serglycin PF04360.7 GAP86572.1 - 0.29 10.8 2.9 0.35 10.5 1.0 1.9 1 1 0 1 1 1 0 Serglycin Fasciclin PF02469.17 GAP86573.1 - 3.6e-24 85.1 0.0 2.9e-17 62.8 0.0 2.7 2 1 0 2 2 2 2 Fasciclin domain Trypan_PARP PF05887.6 GAP86573.1 - 0.061 13.1 8.5 0.15 11.8 5.9 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF1690 PF07956.6 GAP86576.1 - 6.1e-34 117.0 5.9 7.1e-34 116.8 4.1 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Bac_GDH PF05088.7 GAP86576.1 - 0.013 12.9 0.6 0.017 12.5 0.2 1.4 1 1 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase Borrelia_P83 PF05262.6 GAP86576.1 - 0.016 13.4 6.7 0.02 13.2 4.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein BRE1 PF08647.6 GAP86576.1 - 0.11 12.4 6.8 0.037 14.0 2.5 1.9 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase BIV_Env PF05858.7 GAP86576.1 - 0.13 10.1 0.5 0.15 9.9 0.3 1.1 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) PGA2 PF07543.7 GAP86576.1 - 0.3 10.8 4.5 0.41 10.4 3.1 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 KfrA_N PF11740.3 GAP86576.1 - 0.46 10.9 13.1 0.84 10.1 8.1 1.9 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term PAP_central PF04928.12 GAP86576.1 - 0.58 8.9 2.8 0.75 8.5 1.9 1.2 1 0 0 1 1 1 0 Poly(A) polymerase central domain FUSC PF04632.7 GAP86576.1 - 0.59 8.5 4.0 0.62 8.4 2.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family HR1 PF02185.11 GAP86576.1 - 1.5 8.6 7.1 2.7 7.8 3.4 2.4 2 1 1 3 3 3 0 Hr1 repeat HrpA_pilin PF09589.5 GAP86576.1 - 2.8 8.3 6.0 5.8 7.3 4.2 1.5 1 1 0 1 1 1 0 HrpA pilus formation protein TYW3 PF02676.9 GAP86577.1 - 2.9e-59 199.6 0.0 3.9e-59 199.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TYW3 SUI1 PF01253.17 GAP86577.1 - 5.6e-28 96.5 4.3 1.1e-27 95.6 3.0 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 AdoMet_MTase PF07757.8 GAP86578.1 - 4.5e-36 123.3 0.0 9.6e-36 122.3 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase B3_4 PF03483.12 GAP86578.1 - 4.2e-26 91.4 0.0 6.8e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 GAP86578.1 - 5.6e-18 64.5 0.0 1.7e-13 50.1 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetase B5 domain Methyltransf_23 PF13489.1 GAP86578.1 - 0.00098 18.8 0.1 0.0043 16.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 GAP86578.1 - 0.0053 16.4 0.1 1.4 8.5 0.0 3.2 2 1 0 2 2 2 1 Methyltransferase domain Herpes_V23 PF01802.12 GAP86578.1 - 0.11 11.4 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein Methyltransf_18 PF12847.2 GAP86578.1 - 0.15 12.6 0.0 0.47 11.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Adaptin_N PF01602.15 GAP86579.1 - 2.9e-113 378.9 1.1 3.8e-113 378.5 0.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 GAP86579.1 - 4.9e-57 191.9 2.9 1e-56 190.9 2.0 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 GAP86579.1 - 1.1e-15 57.6 1.6 2e-05 24.7 0.1 5.9 2 1 3 5 5 5 3 HEAT repeats HEAT_PBS PF03130.11 GAP86579.1 - 0.00051 20.2 0.1 0.98 10.0 0.0 4.3 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat DUF3730 PF12530.3 GAP86579.1 - 0.021 14.7 2.7 1.4 8.8 0.7 3.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3730) Alpha_adaptin_C PF02296.11 GAP86579.1 - 0.052 13.5 0.0 0.17 11.8 0.0 1.9 1 0 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain DUF1548 PF07579.6 GAP86579.1 - 0.077 13.1 0.5 6.7 6.8 0.1 3.2 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1548) HEAT_EZ PF13513.1 GAP86579.1 - 0.22 12.0 3.6 0.8 10.2 0.7 3.1 2 0 0 2 2 2 0 HEAT-like repeat HEAT PF02985.17 GAP86579.1 - 7.8 6.8 13.2 2.6 8.3 0.3 4.9 7 0 0 7 7 7 0 HEAT repeat CDP-OH_P_transf PF01066.16 GAP86580.1 - 1.4e-17 63.8 1.2 1.4e-17 63.8 0.8 2.4 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase bZIP_1 PF00170.16 GAP86581.1 - 5.8e-08 32.5 12.8 1.1e-07 31.7 8.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 GAP86581.1 - 0.00078 19.6 10.4 0.0014 18.9 7.2 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor LMSTEN PF07988.7 GAP86581.1 - 0.03 13.6 2.7 4.6 6.6 0.9 2.8 2 1 1 3 3 3 0 LMSTEN motif Rabaptin PF03528.10 GAP86581.1 - 0.065 13.1 5.9 2.5 8.0 3.5 2.4 2 0 0 2 2 2 0 Rabaptin V_ATPase_I PF01496.14 GAP86581.1 - 0.21 9.3 2.2 0.28 8.9 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.10 GAP86581.1 - 0.29 10.9 17.2 1.2 8.9 10.7 2.1 1 1 1 2 2 2 0 Basic region leucine zipper M PF02370.11 GAP86581.1 - 0.85 10.1 3.2 11 6.7 0.6 2.6 2 0 0 2 2 2 0 M protein repeat PAT1 PF09770.4 GAP86581.1 - 7.2 4.7 18.6 9.5 4.3 12.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Transp_cyt_pur PF02133.10 GAP86583.1 - 7.2e-33 113.8 30.7 4e-32 111.3 21.2 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin AA_permease_2 PF13520.1 GAP86584.1 - 3.9e-53 180.5 59.0 4.8e-53 180.2 40.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAP86584.1 - 6.9e-18 64.2 44.8 9.2e-18 63.8 31.0 1.1 1 0 0 1 1 1 1 Amino acid permease CcmD PF04995.9 GAP86584.1 - 9 6.1 9.2 0.67 9.7 1.0 3.3 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) Xpo1 PF08389.7 GAP86586.1 - 0.041 13.8 0.1 2.6 7.9 0.0 2.6 2 0 0 2 2 2 0 Exportin 1-like protein NPP PF08384.5 GAP86586.1 - 0.17 11.5 0.7 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 Pro-opiomelanocortin, N-terminal region ATP12 PF07542.6 GAP86587.1 - 1.5e-30 105.6 0.0 2.3e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein DLH PF01738.13 GAP86590.1 - 1.2e-11 44.3 0.0 1.5e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 GAP86590.1 - 2.7e-05 23.9 0.0 5.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family NUDIX PF00293.23 GAP86591.1 - 3.1e-08 33.3 0.1 1.1e-07 31.5 0.1 2.0 1 1 0 1 1 1 1 NUDIX domain Acyl-CoA_dh_1 PF00441.19 GAP86592.1 - 1.5e-32 112.7 0.4 5.8e-32 110.8 0.3 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAP86592.1 - 5.9e-30 104.1 0.3 1.3e-29 103.0 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 GAP86592.1 - 6.2e-19 67.2 0.3 1.3e-18 66.2 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 GAP86592.1 - 2.5e-12 47.1 3.0 5.3e-11 42.8 0.2 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 GAP86592.1 - 0.0017 17.8 0.8 0.0088 15.4 0.6 2.1 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Carboxyl_trans PF01039.17 GAP86593.1 - 3e-143 477.7 0.1 4e-143 477.3 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 GAP86593.1 - 0.15 11.2 1.9 7.1 5.7 0.0 3.0 3 0 0 3 3 3 0 Malonate decarboxylase gamma subunit (MdcE) RTC PF01137.16 GAP86595.1 - 1.1e-42 145.4 0.0 1.5e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase EST1_DNA_bind PF10373.4 GAP86596.1 - 3.2e-19 69.1 0.1 5.8e-18 65.0 0.1 2.5 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain CAF-1_p60_C PF15512.1 GAP86599.1 - 0.075 13.4 1.1 0.17 12.3 0.8 1.7 1 0 0 1 1 1 0 Chromatin assembly factor complex 1 subunit p60, C-terminal SIP1 PF04938.7 GAP86600.1 - 2.3e-06 27.1 0.1 0.1 11.9 0.0 3.2 3 0 0 3 3 3 3 Survival motor neuron (SMN) interacting protein 1 (SIP1) RNR_inhib PF08591.5 GAP86601.1 - 1.9e-19 70.3 1.0 2.1e-18 67.0 0.0 2.8 3 0 0 3 3 3 1 Ribonucleotide reductase inhibitor Med25_NR-box PF11244.3 GAP86601.1 - 1.5 9.3 4.4 11 6.5 0.1 2.9 3 0 0 3 3 3 0 Mediator complex subunit 25 C-terminal NR box-containing Ribosomal_S27e PF01667.12 GAP86602.1 - 2.1e-28 97.6 7.4 2.7e-28 97.2 5.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 GAP86602.1 - 0.0093 15.8 1.5 0.011 15.6 1.0 1.2 1 0 0 1 1 1 1 IBR domain TF_Zn_Ribbon PF08271.7 GAP86602.1 - 0.3 10.4 3.3 0.41 10.0 2.3 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding Phosducin PF02114.11 GAP86603.1 - 1.3e-12 46.9 0.1 2e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 GAP86603.1 - 0.032 13.9 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin DUF3503 PF12011.3 GAP86603.1 - 0.058 13.1 0.0 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3503) LRR_8 PF13855.1 GAP86604.1 - 3.6e-10 39.4 5.6 3.6e-10 39.4 3.9 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.2 GAP86604.1 - 2.7e-09 36.4 12.5 4.3e-09 35.8 3.8 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAP86604.1 - 1e-05 24.9 14.6 0.027 14.4 0.1 4.5 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 GAP86604.1 - 0.00021 20.9 9.5 0.83 10.1 0.1 4.2 3 0 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 GAP86604.1 - 0.049 13.7 3.2 23 5.4 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich repeat alpha-hel2 PF14456.1 GAP86604.1 - 0.23 10.2 0.0 0.38 9.4 0.0 1.3 1 0 0 1 1 1 0 Alpha-helical domain 2 DUF3317 PF11779.3 GAP86605.1 - 1.2e-13 50.2 3.3 1.8e-13 49.7 2.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) DUF1624 PF07786.7 GAP86605.1 - 0.0081 15.5 0.1 0.0093 15.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1624) AMP-binding PF00501.23 GAP86606.1 - 1.3e-57 195.1 0.8 6.2e-45 153.3 0.0 3.2 1 1 2 3 3 3 3 AMP-binding enzyme AMP-binding_C PF13193.1 GAP86606.1 - 9e-16 58.5 0.4 2.4e-15 57.2 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Gly_transf_sug PF04488.10 GAP86607.1 - 2.3e-12 47.2 0.0 4.7e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 GAP86607.1 - 0.14 10.5 0.3 4.4 5.6 0.1 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain CAF-1_p150 PF11600.3 GAP86609.1 - 0.037 13.4 4.5 0.046 13.1 2.8 1.4 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal ATP-synt_B PF00430.13 GAP86609.1 - 0.56 10.0 5.5 0.79 9.5 3.8 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Nop53 PF07767.6 GAP86609.1 - 2.5 6.9 8.7 3.6 6.4 6.1 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF3237 PF11578.3 GAP86610.1 - 2.4e-19 69.1 0.1 5.4e-19 67.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3237) Fungal_trans_2 PF11951.3 GAP86611.1 - 8.7e-07 27.8 0.2 3.2e-05 22.6 0.1 2.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Ferric_reduct PF01794.14 GAP86612.1 - 4.5e-21 75.2 10.6 4.5e-21 75.2 7.3 2.4 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 GAP86612.1 - 1.7e-17 63.7 0.0 8.2e-16 58.2 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 GAP86612.1 - 2.2e-11 43.5 0.0 1.7e-10 40.6 0.0 2.3 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 GAP86612.1 - 0.072 13.6 0.0 0.19 12.3 0.0 1.8 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain HEAT PF02985.17 GAP86613.1 - 7.8e-14 50.4 13.3 0.0021 18.0 0.0 10.2 12 0 0 12 12 12 3 HEAT repeat HEAT_EZ PF13513.1 GAP86613.1 - 2.8e-13 49.9 4.4 8.7e-08 32.4 0.0 8.1 9 1 2 11 11 11 1 HEAT-like repeat HEAT_2 PF13646.1 GAP86613.1 - 1.3e-12 47.7 11.9 1.7e-06 28.2 0.0 7.3 2 2 6 8 8 8 4 HEAT repeats IBN_N PF03810.14 GAP86613.1 - 1.8e-09 37.4 1.5 1.8e-09 37.4 1.1 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain RIX1 PF08167.7 GAP86613.1 - 0.00022 20.9 1.5 0.12 12.0 0.1 4.7 2 1 3 5 5 5 1 rRNA processing/ribosome biogenesis Arm PF00514.18 GAP86613.1 - 0.011 15.5 4.4 36 4.4 0.0 6.2 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat DUF1548 PF07579.6 GAP86613.1 - 1 9.4 6.6 5 7.2 0.0 3.9 4 1 1 5 5 5 0 Domain of Unknown Function (DUF1548) Fungal_trans PF04082.13 GAP86614.1 - 9.6e-17 60.7 0.0 1.6e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP86614.1 - 0.011 15.5 9.7 0.02 14.7 6.7 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 GAP86614.1 - 6 4.9 36.1 10 4.1 25.0 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sec2p PF06428.6 GAP86615.1 - 1.3e-25 89.1 12.2 1.3e-25 89.1 8.5 2.5 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p DASH_Hsk3 PF08227.6 GAP86615.1 - 1.9 8.7 6.1 1.2 9.3 2.0 2.4 2 1 0 2 2 2 0 DASH complex subunit Hsk3 like GDI PF00996.13 GAP86616.1 - 7.5e-40 136.5 0.0 1.7e-39 135.4 0.0 1.5 1 1 0 1 1 1 1 GDP dissociation inhibitor Rad21_Rec8_N PF04825.8 GAP86617.1 - 9.4e-28 96.3 0.0 1.8e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 GAP86617.1 - 6.6e-09 34.8 0.0 1.5e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ALO PF04030.9 GAP86618.1 - 5.5e-90 301.4 1.7 7.3e-90 301.0 1.2 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 GAP86618.1 - 1.4e-29 102.3 0.0 2.1e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain RNase_PH PF01138.16 GAP86620.1 - 3.5e-19 69.4 0.0 7e-19 68.4 0.0 1.5 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 GAP86620.1 - 0.081 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Ferric_reduct PF01794.14 GAP86621.1 - 1.8e-17 63.6 3.4 1.8e-17 63.6 2.3 2.2 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 GAP86621.1 - 2e-14 53.3 0.1 6.2e-14 51.7 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 GAP86621.1 - 1.4e-12 47.7 0.0 3.1e-08 33.6 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 GAP86621.1 - 0.00034 21.1 0.0 0.15 12.6 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Nop14 PF04147.7 GAP86624.1 - 0.17 9.7 0.9 0.35 8.7 0.6 1.4 1 0 0 1 1 1 0 Nop14-like family CD20 PF04103.10 GAP86624.1 - 2.5 8.0 0.0 6.1 6.7 0.0 1.6 1 0 0 1 1 1 0 CD20-like family SNARE PF05739.14 GAP86626.1 - 7.7e-18 63.9 6.7 1.1e-17 63.4 0.5 2.7 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 GAP86626.1 - 2.3e-16 59.8 0.6 2.3e-16 59.8 0.4 3.2 4 1 0 4 4 4 1 Syntaxin Atg14 PF10186.4 GAP86626.1 - 0.00027 19.9 6.9 0.0089 15.0 0.0 3.0 3 0 0 3 3 3 2 UV radiation resistance protein and autophagy-related subunit 14 MCPsignal PF00015.16 GAP86626.1 - 0.0053 16.3 0.8 0.0053 16.3 0.6 2.6 2 1 1 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Sed5p PF11416.3 GAP86626.1 - 0.015 14.7 0.0 0.033 13.6 0.0 1.6 1 0 0 1 1 1 0 Integral membrane protein Sed5p Syntaxin-18_N PF10496.4 GAP86626.1 - 0.041 13.7 0.6 0.88 9.4 0.0 2.8 2 1 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus NPV_P10 PF05531.7 GAP86626.1 - 0.21 11.8 9.2 13 6.1 0.1 3.8 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 GAP86626.1 - 0.23 10.6 3.2 11 5.0 0.9 2.5 2 1 1 3 3 3 0 Reovirus sigma C capsid protein zf-C4H2 PF10146.4 GAP86626.1 - 0.36 10.8 3.4 0.98 9.3 0.2 2.2 1 1 0 2 2 2 0 Zinc finger-containing protein BLOC1_2 PF10046.4 GAP86626.1 - 0.85 9.7 4.9 1.4 9.1 0.3 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SF-assemblin PF06705.6 GAP86626.1 - 2.1 7.4 10.5 0.23 10.6 1.0 2.6 3 0 0 3 3 3 0 SF-assemblin/beta giardin MitMem_reg PF13012.1 GAP86626.1 - 6.3 6.9 7.1 3.6 7.6 0.7 2.7 3 0 0 3 3 3 0 Maintenance of mitochondrial structure and function Aldo_ket_red PF00248.16 GAP86627.1 - 7.5e-44 149.6 0.0 9e-44 149.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1737 PF08410.5 GAP86627.1 - 0.068 12.9 0.1 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) NACHT PF05729.7 GAP86628.1 - 4.7e-07 29.6 0.0 1.1e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAP86628.1 - 0.00041 20.5 0.1 0.0053 16.8 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 GAP86628.1 - 0.0025 17.8 0.5 0.017 15.1 0.0 2.6 4 0 0 4 4 4 1 AAA ATPase domain AAA_18 PF13238.1 GAP86628.1 - 0.0062 16.8 0.4 0.19 12.0 0.0 3.2 4 0 0 4 4 4 1 AAA domain AAA_10 PF12846.2 GAP86628.1 - 0.0063 15.9 0.3 0.022 14.2 0.1 2.0 2 0 0 2 2 2 1 AAA-like domain ABC_tran PF00005.22 GAP86628.1 - 0.017 15.4 0.1 0.063 13.5 0.0 2.0 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.17 GAP86628.1 - 0.018 15.2 0.0 0.05 13.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.1 GAP86628.1 - 0.046 14.5 0.0 0.21 12.4 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_29 PF13555.1 GAP86628.1 - 0.056 12.9 0.1 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.10 GAP86628.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_23 PF13476.1 GAP86628.1 - 0.29 11.4 0.1 0.29 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain ADH_N PF08240.7 GAP86629.1 - 2.3e-26 91.6 0.2 2.3e-26 91.6 0.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAP86629.1 - 6.6e-17 61.2 0.8 6.6e-17 61.2 0.6 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase FAD_binding_2 PF00890.19 GAP86629.1 - 0.0081 15.0 1.6 0.012 14.4 1.1 1.2 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 GAP86629.1 - 0.16 11.5 5.3 0.077 12.5 1.3 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.16 GAP86629.1 - 1.1 9.0 5.2 0.23 11.3 0.8 1.9 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain HI0933_like PF03486.9 GAP86629.1 - 3.6 5.9 8.2 1.3 7.4 3.9 1.5 2 0 0 2 2 2 0 HI0933-like protein adh_short PF00106.20 GAP86630.1 - 8.6e-33 113.5 1.3 1.3e-32 113.0 0.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP86630.1 - 3.5e-24 85.8 0.0 4.6e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP86630.1 - 2.2e-16 60.0 1.0 5.4e-16 58.7 0.7 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 GAP86630.1 - 9.3e-08 31.7 0.0 1.2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAP86630.1 - 0.00064 19.4 0.5 0.0015 18.2 0.3 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 GAP86630.1 - 0.0013 18.7 1.2 0.0029 17.6 0.8 1.9 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 GAP86630.1 - 0.0064 15.4 0.5 0.021 13.6 0.1 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain PALP PF00291.20 GAP86630.1 - 0.0097 15.1 0.2 0.03 13.5 0.1 1.7 1 1 1 2 2 2 1 Pyridoxal-phosphate dependent enzyme 2-Hacid_dh_C PF02826.14 GAP86630.1 - 0.052 12.6 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1815 PF08844.5 GAP86630.1 - 0.077 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) NmrA PF05368.8 GAP86630.1 - 0.14 11.4 3.7 0.053 12.7 0.5 1.8 2 1 0 2 2 2 0 NmrA-like family Acetyltransf_1 PF00583.19 GAP86632.1 - 4e-12 46.0 0.0 6.3e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAP86632.1 - 1.8e-10 40.8 0.1 2.6e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAP86632.1 - 0.0058 16.7 0.0 0.0076 16.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAP86632.1 - 0.0083 15.9 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AstA PF04958.7 GAP86632.1 - 0.014 13.8 0.0 0.018 13.4 0.0 1.1 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit Acetyltransf_4 PF13420.1 GAP86632.1 - 0.048 13.6 0.0 0.068 13.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Lipase_3 PF01764.20 GAP86633.1 - 1.2e-14 54.1 0.0 1.3e-13 50.7 0.0 2.2 1 1 0 1 1 1 1 Lipase (class 3) Glyco_hydro_43 PF04616.9 GAP86634.1 - 2.9e-21 75.8 0.1 1.4e-11 44.0 0.0 2.5 2 1 0 2 2 2 2 Glycosyl hydrolases family 43 HET PF06985.6 GAP86635.1 - 1e-17 64.6 0.2 2.7e-17 63.2 0.0 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) GXWXG PF14231.1 GAP86635.1 - 0.047 13.3 0.2 0.62 9.7 0.0 2.6 2 0 0 2 2 2 0 GXWXG protein adh_short_C2 PF13561.1 GAP86636.1 - 4.2e-28 98.7 0.8 6e-28 98.2 0.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAP86636.1 - 5.3e-20 72.0 3.4 8.5e-20 71.3 2.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP86636.1 - 0.00017 21.2 0.9 0.0003 20.4 0.6 1.3 1 0 0 1 1 1 1 KR domain Zn_clus PF00172.13 GAP86636.1 - 0.006 16.4 4.9 0.006 16.4 3.4 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phage_HK97_TLTM PF06120.6 GAP86636.1 - 0.019 14.3 0.1 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Tail length tape measure protein 2-Hacid_dh_C PF02826.14 GAP86636.1 - 0.042 12.9 0.4 0.08 12.0 0.3 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YjeF_N PF03853.10 GAP86636.1 - 0.074 12.6 1.3 0.085 12.4 0.1 1.6 2 0 0 2 2 2 0 YjeF-related protein N-terminus zf-met PF12874.2 GAP86636.1 - 0.19 11.9 1.5 0.48 10.6 1.1 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type 3HCDH_N PF02737.13 GAP86636.1 - 0.62 9.6 3.6 0.17 11.5 0.2 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-C2H2_jaz PF12171.3 GAP86636.1 - 1.3 9.2 8.8 0.032 14.3 1.4 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding p450 PF00067.17 GAP86637.1 - 7.5e-54 182.9 0.0 2.3e-51 174.7 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 GAP86638.1 - 1.6e-57 195.0 0.0 4.5e-56 190.2 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 PhyH PF05721.8 GAP86639.1 - 2e-23 83.5 0.0 2.7e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Methyltransf_2 PF00891.13 GAP86641.1 - 8e-17 61.2 0.0 7e-10 38.5 0.0 2.8 2 1 0 2 2 2 2 O-methyltransferase Adeno_E3_CR2 PF02439.10 GAP86642.1 - 0.0016 17.9 0.1 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF1183 PF06682.7 GAP86642.1 - 0.032 13.8 0.0 0.039 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF1191 PF06697.7 GAP86642.1 - 0.041 12.6 0.0 0.054 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF1206 PF06724.6 GAP86642.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) Epimerase PF01370.16 GAP86643.1 - 1.1e-26 93.8 0.0 1.4e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAP86643.1 - 2.9e-13 49.1 0.0 3.9e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAP86643.1 - 3.1e-12 46.8 0.2 4.6e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAP86643.1 - 1e-11 44.2 0.0 2.3e-11 43.1 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 GAP86643.1 - 5.5e-07 29.6 0.0 1.2e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 GAP86643.1 - 0.00011 21.1 0.0 0.00018 20.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 GAP86643.1 - 0.00017 20.8 0.0 0.0038 16.5 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family Saccharop_dh PF03435.13 GAP86643.1 - 0.00096 18.2 0.0 0.011 14.7 0.0 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase KR PF08659.5 GAP86643.1 - 0.0019 17.9 0.0 0.0038 16.9 0.0 1.5 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 GAP86643.1 - 0.0023 18.0 0.0 0.0042 17.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.12 GAP86643.1 - 0.021 13.6 0.0 0.049 12.5 0.0 1.6 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short_C2 PF13561.1 GAP86643.1 - 0.035 13.8 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase FAD_binding_3 PF01494.14 GAP86644.1 - 6.3e-08 32.0 0.1 8.8e-08 31.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Mcp5_PH PF12814.2 GAP86646.1 - 9.6e-41 138.5 0.1 5.8e-40 136.0 0.0 2.4 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology zf-CCCH PF00642.19 GAP86647.1 - 2.6e-08 33.3 2.6 4.8e-08 32.4 1.8 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 GAP86647.1 - 5.4e-07 29.1 4.1 9e-07 28.4 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAP86647.1 - 1.1e-06 28.5 9.0 2e-06 27.7 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAP86647.1 - 1.3e-06 27.8 7.3 2.6e-06 26.9 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAP86647.1 - 7.3e-05 22.4 7.1 0.00012 21.6 4.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 GAP86647.1 - 0.00011 21.9 6.7 0.00019 21.1 4.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 GAP86647.1 - 0.0086 15.9 8.5 0.019 14.8 5.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 GAP86647.1 - 0.016 14.9 1.7 0.038 13.7 1.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger PEP_mutase PF13714.1 GAP86648.1 - 1.5e-55 188.0 4.2 1.7e-55 187.8 2.9 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Gly_transf_sug PF04488.10 GAP86649.1 - 1.2e-08 35.2 0.0 2.4e-08 34.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DnaJ PF00226.26 GAP86650.1 - 7.1e-20 70.5 0.7 7.1e-20 70.5 0.5 2.8 2 1 0 2 2 2 1 DnaJ domain DUF2803 PF10972.3 GAP86650.1 - 0.35 10.3 8.2 0.1 12.0 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2803) V_ATPase_I PF01496.14 GAP86650.1 - 1.3 6.8 10.1 2.3 5.9 7.0 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Complex1_LYR PF05347.10 GAP86651.1 - 0.00027 20.6 0.0 0.0007 19.3 0.0 1.7 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAP86651.1 - 0.0011 19.1 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like RRM_5 PF13893.1 GAP86652.1 - 1.4e-09 37.6 0.0 2.5e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAP86652.1 - 3e-08 33.1 0.0 5.5e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP86652.1 - 9.9e-06 25.4 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAP86652.1 - 0.00053 19.7 0.1 0.001 18.7 0.1 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 GAP86652.1 - 0.075 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif MFS_1 PF07690.11 GAP86653.1 - 1.8e-30 105.8 24.4 1.8e-30 105.8 16.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily PAN_1 PF00024.21 GAP86654.1 - 0.081 12.6 0.7 0.37 10.5 0.1 2.1 2 0 0 2 2 2 0 PAN domain Fungal_trans PF04082.13 GAP86655.1 - 6.5e-13 48.1 0.1 9.7e-13 47.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP86655.1 - 1.2e-06 28.3 11.2 1.9e-06 27.6 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.16 GAP86657.1 - 6e-05 22.5 0.0 0.0002 20.8 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAP86657.1 - 0.0019 18.2 0.1 0.0033 17.4 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 GAP86658.1 - 9e-18 64.7 0.1 5.1e-16 59.0 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAP86658.1 - 9.2e-09 35.2 0.0 1.3e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAP86658.1 - 4.2e-08 33.2 0.0 9.3e-07 28.8 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Saccharop_dh PF03435.13 GAP86658.1 - 0.0089 15.0 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 GAP86658.1 - 0.026 13.4 0.0 0.054 12.4 0.0 1.5 1 1 0 1 1 1 0 Male sterility protein 3Beta_HSD PF01073.14 GAP86658.1 - 0.11 11.2 0.3 0.32 9.6 0.2 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.11 GAP86660.1 - 4.6e-14 51.9 52.9 4.9e-14 51.7 21.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M24 PF00557.19 GAP86661.1 - 2.9e-10 40.0 0.0 3.8e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Ribosomal_60s PF00428.14 GAP86662.1 - 0.76 10.2 6.2 1.1 9.7 4.3 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Herpes_capsid PF06112.6 GAP86662.1 - 4.3 7.3 7.5 4.4 7.3 5.2 1.0 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Pkinase PF00069.20 GAP86663.1 - 6.3e-42 143.5 2.9 1.4e-24 86.7 0.2 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAP86663.1 - 6.2e-15 54.9 0.3 2.8e-10 39.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Med26 PF08711.6 GAP86664.1 - 1e-11 44.1 0.0 2e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Sec23_helical PF04815.10 GAP86664.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Sec23/Sec24 helical domain Brr6_like_C_C PF10104.4 GAP86665.1 - 3.3e-29 101.1 0.1 5e-29 100.5 0.1 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain PBP1_TM PF14812.1 GAP86665.1 - 0.074 13.3 0.5 0.074 13.3 0.3 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TMEMspv1-c74-12 PF11044.3 GAP86665.1 - 8.1 6.0 5.4 39 3.9 0.8 2.4 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Fungal_trans PF04082.13 GAP86666.1 - 2.8e-24 85.3 0.3 2.8e-24 85.3 0.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP86666.1 - 4.6e-08 32.8 12.7 9.5e-08 31.8 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-met PF12874.2 GAP86667.1 - 0.00014 21.9 6.9 0.018 15.2 0.5 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 GAP86667.1 - 0.001 19.2 5.3 0.058 13.7 0.2 3.3 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 GAP86667.1 - 0.036 14.1 1.3 0.036 14.1 0.9 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 GAP86667.1 - 0.06 13.7 15.7 0.055 13.8 1.7 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF3449 PF11931.3 GAP86667.1 - 0.06 12.8 5.1 0.23 10.9 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3449) Mut7-C PF01927.11 GAP86667.1 - 1.8 8.5 6.5 16 5.4 0.7 2.4 1 1 1 2 2 2 0 Mut7-C RNAse domain BAF1_ABF1 PF04684.8 GAP86667.1 - 1.8 7.2 20.8 3.2 6.5 14.4 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Arylsulfotran_2 PF14269.1 GAP86668.1 - 4e-52 177.2 0.0 5.5e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 GAP86668.1 - 2.5e-16 59.2 0.0 5.6e-16 58.1 0.0 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) eIF-4B PF06273.6 GAP86668.1 - 0.19 10.4 0.6 0.26 9.9 0.4 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Globin PF00042.17 GAP86669.1 - 8.1e-09 35.8 0.0 1.3e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.16 GAP86669.1 - 1.6e-08 35.0 0.0 2.9e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 GAP86669.1 - 6.2e-07 29.4 0.0 7.5e-06 26.0 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.3 GAP86669.1 - 0.00013 21.6 0.1 0.00022 20.9 0.1 1.4 1 0 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.7 GAP86669.1 - 0.0071 16.2 0.1 0.92 9.3 0.0 2.8 2 1 1 3 3 3 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 GAP86669.1 - 0.019 14.8 0.0 0.069 13.0 0.0 1.9 1 1 1 2 2 2 0 FAD-binding domain DUF3431 PF11913.3 GAP86670.1 - 8e-88 293.6 0.0 1.1e-87 293.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) UQ_con PF00179.21 GAP86672.1 - 3e-11 42.9 0.0 5.2e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme F-box-like PF12937.2 GAP86672.1 - 0.0014 18.2 0.1 0.003 17.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like RWD PF05773.17 GAP86672.1 - 0.0094 15.8 0.4 0.019 14.8 0.3 1.5 1 0 0 1 1 1 1 RWD domain F-box PF00646.28 GAP86672.1 - 0.02 14.5 1.1 0.034 13.8 0.2 1.8 2 0 0 2 2 2 0 F-box domain GST_N_3 PF13417.1 GAP86673.1 - 8.6e-06 25.8 0.0 1.6e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAP86673.1 - 0.00024 21.0 0.0 0.00044 20.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAP86673.1 - 0.00039 20.3 0.0 0.00068 19.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAP86673.1 - 0.00078 19.5 0.0 0.0027 17.8 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAP86673.1 - 0.0026 17.6 0.2 0.0057 16.5 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Inhibitor_I71 PF12628.2 GAP86673.1 - 0.15 11.7 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor FAD_binding_3 PF01494.14 GAP86674.1 - 0.054 12.5 2.5 0.2 10.7 0.1 2.4 3 0 0 3 3 3 0 FAD binding domain SAICAR_synt PF01259.13 GAP86675.1 - 3.5e-78 262.1 0.0 4.3e-78 261.8 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Cutinase PF01083.17 GAP86676.1 - 3.8e-44 150.5 0.2 4.6e-44 150.2 0.1 1.1 1 0 0 1 1 1 1 Cutinase VirJ PF06057.6 GAP86676.1 - 0.0017 18.2 0.0 0.0026 17.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.6 GAP86676.1 - 0.0023 17.3 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.2 GAP86676.1 - 0.0032 17.3 0.3 0.0036 17.2 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 GAP86676.1 - 0.04 13.5 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.3 GAP86676.1 - 0.066 12.5 0.1 0.095 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.8 GAP86676.1 - 0.083 12.4 1.6 0.31 10.5 0.6 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF2296 PF10058.4 GAP86678.1 - 6.8e-18 64.1 0.1 1.2e-17 63.3 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) CCDC-167 PF15188.1 GAP86678.1 - 0.063 13.2 2.0 0.59 10.1 0.0 2.6 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 CDC45 PF02724.9 GAP86678.1 - 0.068 11.1 4.8 0.075 11.0 0.2 2.0 2 0 0 2 2 2 0 CDC45-like protein Sugarporin_N PF11471.3 GAP86678.1 - 4.9 6.8 6.4 0.71 9.5 0.1 2.6 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension GRIP PF01465.15 GAP86679.1 - 2e-10 39.9 0.0 4.9e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 GRIP domain FlpD PF02662.11 GAP86679.1 - 3.4 7.3 5.2 38 3.9 1.5 3.3 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit CoA_transf_3 PF02515.12 GAP86680.1 - 0.0091 15.2 1.6 0.069 12.3 0.0 2.3 2 0 0 2 2 2 2 CoA-transferase family III Sugar_tr PF00083.19 GAP86681.1 - 1.4e-78 264.4 19.6 1.6e-78 264.2 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP86681.1 - 7.2e-25 87.4 29.2 4.5e-22 78.2 12.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAP86681.1 - 0.00016 20.0 1.6 0.00031 19.0 1.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Gate PF07670.9 GAP86681.1 - 4.5 7.2 10.4 4.5 7.2 1.2 3.1 3 0 0 3 3 3 0 Nucleoside recognition Amidohydro_1 PF01979.15 GAP86682.1 - 1.2e-30 107.3 0.0 1.5e-30 106.9 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 GAP86682.1 - 1.8e-09 37.3 0.0 2e-06 27.3 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 GAP86682.1 - 3.1e-08 33.9 0.1 0.0015 18.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 GAP86682.1 - 1.4e-05 24.8 0.0 4.6e-05 23.1 0.0 2.0 1 1 1 2 2 2 1 Amidohydrolase A_deaminase PF00962.17 GAP86682.1 - 0.00025 20.0 0.0 0.00044 19.2 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase tRNA-synt_2 PF00152.15 GAP86683.1 - 2.1e-89 299.6 0.8 3.2e-89 299.0 0.5 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 GAP86683.1 - 2.6e-06 26.8 0.2 0.0052 16.0 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 GAP86683.1 - 2.7e-05 23.9 0.0 5.9e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 GAP86683.1 - 0.0058 16.2 0.1 0.67 9.5 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Peptidase_S49_N PF08496.5 GAP86683.1 - 3.3 7.4 6.8 7.3 6.3 4.7 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Borrelia_P83 PF05262.6 GAP86683.1 - 3.7 5.7 10.3 5.1 5.2 7.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Trypan_PARP PF05887.6 GAP86684.1 - 0.0029 17.4 1.5 0.0037 17.0 1.0 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Herpes_UL25 PF01499.11 GAP86684.1 - 1.2 7.3 3.8 1.4 7.1 2.7 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family Glyco_hydro_17 PF00332.13 GAP86687.1 - 7.4e-09 35.0 0.8 5.4e-06 25.6 0.1 2.4 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 P12 PF12669.2 GAP86687.1 - 3 8.0 5.2 0.51 10.5 0.5 2.0 2 0 0 2 2 2 0 Virus attachment protein p12 family Nop14 PF04147.7 GAP86688.1 - 0.17 9.7 1.4 0.21 9.4 1.0 1.1 1 0 0 1 1 1 0 Nop14-like family Trypan_PARP PF05887.6 GAP86688.1 - 0.31 10.8 15.0 0.065 13.0 2.5 3.0 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) SDA1 PF05285.7 GAP86688.1 - 2.3 7.4 5.0 2.9 7.1 3.5 1.1 1 0 0 1 1 1 0 SDA1 DUF1180 PF06679.7 GAP86688.1 - 7.4 6.4 13.1 0.24 11.2 0.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1180) ATG27 PF09451.5 GAP86689.1 - 0.0044 16.3 2.3 0.051 12.7 0.0 2.2 2 0 0 2 2 2 1 Autophagy-related protein 27 PBP1_TM PF14812.1 GAP86689.1 - 0.82 10.0 4.7 1.8 8.9 3.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cytochrom_B562 PF07361.6 GAP86690.1 - 0.025 14.9 2.0 0.12 12.8 0.0 2.7 2 1 1 3 3 3 0 Cytochrome b562 DUF3499 PF12005.3 GAP86690.1 - 2.8 8.1 9.7 3.2 7.9 1.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3499) WD40 PF00400.27 GAP86691.1 - 5.1e-35 118.1 9.6 6.9e-12 44.7 0.1 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_3 PF13570.1 GAP86691.1 - 0.052 13.8 2.3 14 6.1 0.0 3.9 5 0 0 5 5 5 0 PQQ-like domain PFU PF09070.6 GAP86692.1 - 6.6e-42 142.1 2.0 1.3e-41 141.2 1.4 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 GAP86692.1 - 2.8e-41 137.9 9.7 1.6e-07 30.9 0.1 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat PUL PF08324.6 GAP86692.1 - 7.2e-40 136.4 0.5 1.1e-39 135.9 0.4 1.2 1 0 0 1 1 1 1 PUL domain BBS2_Mid PF14783.1 GAP86692.1 - 0.0047 16.6 0.1 11 5.8 0.0 4.1 4 1 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region SRR1 PF07985.7 GAP86694.1 - 3.2e-07 30.1 0.0 6.7e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 SRR1 Peptidase_C48 PF02902.14 GAP86695.1 - 3.7e-08 33.2 0.0 5.3e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain zf-RING_2 PF13639.1 GAP86696.1 - 8e-10 38.3 5.2 8e-10 38.3 3.6 1.8 2 1 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 GAP86696.1 - 3.8e-06 26.9 3.1 3.8e-06 26.9 2.2 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 GAP86696.1 - 4.7e-05 23.1 2.3 4.7e-05 23.1 1.6 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 GAP86696.1 - 0.00012 21.9 4.6 0.0003 20.6 3.2 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_5 PF14634.1 GAP86696.1 - 0.00035 20.2 4.6 0.00035 20.2 3.2 1.9 3 0 0 3 3 3 1 zinc-RING finger domain PHD PF00628.24 GAP86696.1 - 0.00039 20.0 5.4 0.00071 19.2 3.8 1.5 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 GAP86696.1 - 0.00073 19.2 2.2 0.00073 19.2 1.5 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 zf-C3HC4_2 PF13923.1 GAP86696.1 - 0.0013 18.7 2.4 0.0013 18.7 1.7 2.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 GAP86696.1 - 0.0035 16.8 7.3 0.0053 16.3 3.4 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 GAP86696.1 - 0.017 14.7 4.8 0.017 14.7 3.3 2.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 GAP86696.1 - 0.022 14.8 5.1 0.043 13.8 3.6 1.5 1 0 0 1 1 1 0 RING-variant domain Glypican PF01153.14 GAP86696.1 - 0.12 10.9 0.5 0.21 10.1 0.0 1.4 1 1 0 1 1 1 0 Glypican zf-C3HC4_3 PF13920.1 GAP86696.1 - 0.8 9.4 10.7 0.072 12.7 3.4 2.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 GAP86696.1 - 9.9 5.7 8.5 3.4 7.2 0.4 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 Glyco_hydro_92 PF07971.7 GAP86697.1 - 2.2e-168 561.0 0.0 2.7e-168 560.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Ank_2 PF12796.2 GAP86698.1 - 3.6e-92 302.8 0.0 6.9e-19 67.9 0.0 7.1 1 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 GAP86698.1 - 2.1e-71 232.3 6.8 3.4e-06 26.5 0.1 13.6 13 0 0 13 13 13 12 Ankyrin repeat Ank_4 PF13637.1 GAP86698.1 - 3.5e-61 202.5 4.9 1.7e-11 44.3 0.0 10.9 3 2 8 11 11 11 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP86698.1 - 5.8e-55 182.0 13.8 2e-10 40.5 0.1 10.0 2 2 7 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP86698.1 - 1.6e-51 167.1 0.1 0.00043 20.2 0.0 13.2 13 0 0 13 13 13 11 Ankyrin repeat NACHT PF05729.7 GAP86698.1 - 1.4e-09 37.8 0.0 3.9e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAP86698.1 - 0.00059 19.9 0.0 0.0026 17.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 GAP86698.1 - 0.0012 18.9 0.0 0.0057 16.8 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAP86698.1 - 0.0048 16.9 0.0 0.1 12.6 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain DUF1664 PF07889.7 GAP86698.1 - 0.071 12.9 3.3 0.57 9.9 0.1 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) PTPA PF03095.10 GAP86698.1 - 0.11 11.6 1.4 0.2 10.7 0.1 1.9 2 0 0 2 2 2 0 Phosphotyrosyl phosphate activator (PTPA) protein DUF948 PF06103.6 GAP86698.1 - 0.2 11.5 3.9 0.52 10.2 0.9 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) COG2 PF06148.6 GAP86698.1 - 0.44 10.4 2.6 0.69 9.7 0.2 2.6 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.7 GAP86698.1 - 0.49 10.6 5.9 1.4 9.1 0.8 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 GAP86698.1 - 0.87 8.7 7.8 18 4.4 3.8 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Laminin_II PF06009.7 GAP86698.1 - 1.5 8.5 7.9 1.7 8.4 1.0 3.3 3 0 0 3 3 3 0 Laminin Domain II Ferritin_2 PF13668.1 GAP86699.1 - 0.00019 21.4 0.2 0.05 13.5 0.0 2.3 1 1 1 2 2 2 2 Ferritin-like domain WD40 PF00400.27 GAP86700.1 - 3.3e-16 58.4 4.3 0.015 15.1 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat CDC45 PF02724.9 GAP86700.1 - 0.071 11.1 18.6 0.12 10.4 12.9 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF605 PF04652.11 GAP86700.1 - 0.44 9.8 34.0 0.11 11.8 10.2 2.2 2 0 0 2 2 2 0 Vta1 like AAA_12 PF13087.1 GAP86701.1 - 3.7e-35 121.1 0.0 6.7e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAP86701.1 - 2.1e-25 89.6 0.2 1e-14 54.7 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 GAP86701.1 - 3.1e-10 39.6 0.1 6.6e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 GAP86701.1 - 3e-08 33.4 0.1 2.4e-06 27.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 GAP86701.1 - 7.6e-05 22.3 0.0 0.085 12.3 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 GAP86701.1 - 0.0084 15.1 0.5 0.02 13.9 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 GAP86701.1 - 0.0088 15.3 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein UvrD-helicase PF00580.16 GAP86701.1 - 0.017 14.4 0.1 0.67 9.1 0.0 2.5 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_16 PF13191.1 GAP86701.1 - 0.022 14.7 0.2 0.13 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain ResIII PF04851.10 GAP86701.1 - 0.023 14.5 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit KaiC PF06745.8 GAP86701.1 - 0.043 12.9 0.0 0.082 12.0 0.0 1.4 1 0 0 1 1 1 0 KaiC DEAD PF00270.24 GAP86701.1 - 0.044 13.2 0.1 0.099 12.1 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_25 PF13481.1 GAP86701.1 - 0.069 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 GAP86701.1 - 0.12 12.1 0.0 0.56 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2235 PF09994.4 GAP86702.1 - 4.3e-74 249.3 0.1 5.5e-74 249.0 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.6 GAP86702.1 - 5.5e-05 22.9 0.1 0.00013 21.7 0.0 1.6 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF3089 PF11288.3 GAP86702.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Peptidase_M28 PF04389.12 GAP86703.1 - 7.2e-26 91.0 0.1 1.1e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 GAP86703.1 - 1.7e-07 30.9 0.0 2.5e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 TMEM154 PF15102.1 GAP86704.1 - 0.034 13.8 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family HET PF06985.6 GAP86705.1 - 1.2e-18 67.6 0.0 2.5e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) YjeF_N PF03853.10 GAP86706.1 - 3.6e-35 121.0 0.0 4.4e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Ribosomal_S16 PF00886.14 GAP86707.1 - 4.3e-25 87.2 0.1 1.1e-24 85.9 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S16 CPSase_L_D2 PF02786.12 GAP86708.1 - 1.9e-73 246.2 0.0 3e-73 245.5 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 GAP86708.1 - 1.1e-35 121.7 0.0 2.3e-35 120.7 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 GAP86708.1 - 1.6e-34 118.3 0.0 2.8e-34 117.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 GAP86708.1 - 1.5e-17 63.8 0.0 2.9e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 GAP86708.1 - 7.3e-17 60.7 3.6 7.7e-17 60.6 0.8 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 GAP86708.1 - 2.4e-15 56.1 0.0 4.6e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 GAP86708.1 - 2.4e-10 39.9 0.0 0.00059 19.4 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 GAP86708.1 - 1e-06 28.3 0.0 2.5e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 GAP86708.1 - 2.2e-06 27.1 0.0 3.8e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 GAP86708.1 - 0.00015 21.6 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 GAP86708.1 - 0.00027 20.3 0.1 0.2 10.9 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_2 PF12700.2 GAP86708.1 - 0.00089 18.5 0.0 0.44 9.6 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein RimK PF08443.6 GAP86708.1 - 0.0014 18.1 0.0 0.01 15.3 0.0 2.1 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.1 GAP86708.1 - 0.0083 16.4 0.2 6.1 7.2 0.0 3.5 4 0 0 4 4 4 1 HlyD family secretion protein Pyridox_oxidase PF01243.15 GAP86709.1 - 1e-13 51.1 0.0 6.4e-13 48.5 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 GAP86709.1 - 0.012 15.4 0.0 0.26 11.1 0.0 2.2 2 1 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase Gpi16 PF04113.9 GAP86709.1 - 0.017 13.1 0.0 0.021 12.8 0.0 1.1 1 0 0 1 1 1 0 Gpi16 subunit, GPI transamidase component Ank_2 PF12796.2 GAP86710.1 - 4.3e-71 235.3 0.9 3.6e-12 46.4 0.0 7.2 4 2 3 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 GAP86710.1 - 6.6e-51 167.6 7.5 5.4e-05 22.7 0.0 15.4 15 1 0 15 15 15 12 Ankyrin repeat Ank_4 PF13637.1 GAP86710.1 - 1.3e-43 146.5 0.8 2.6e-06 27.8 0.0 11.4 8 4 3 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP86710.1 - 1.3e-37 126.9 5.5 2.3e-05 24.4 0.0 10.9 6 5 7 13 13 13 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP86710.1 - 2.4e-36 120.0 2.1 0.022 14.9 0.0 14.0 14 0 0 14 14 14 10 Ankyrin repeat FCD PF07729.7 GAP86710.1 - 0.17 12.2 2.3 4.1 7.7 0.0 3.8 3 2 1 4 4 4 0 FCD domain Amidohydro_4 PF13147.1 GAP86711.1 - 0.025 14.5 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 Amidohydrolase Ada3 PF10198.4 GAP86711.1 - 0.068 12.9 3.1 0.099 12.3 1.5 1.7 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 HSP70 PF00012.15 GAP86712.1 - 3e-09 35.3 0.5 7.6e-05 20.8 0.0 3.0 3 0 0 3 3 3 3 Hsp70 protein BPL_LplA_LipB PF03099.14 GAP86713.1 - 3.2e-09 36.8 0.1 1.2e-08 35.0 0.0 1.9 2 1 0 2 2 2 1 Biotin/lipoate A/B protein ligase family Peptidase_C65 PF10275.4 GAP86714.1 - 1.7e-61 207.6 0.0 2.7e-61 207.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase C65 Otubain Med15 PF09606.5 GAP86714.1 - 0.9 7.6 35.0 1.6 6.8 24.2 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Neur_chan_memb PF02932.11 GAP86714.1 - 8.3 6.2 6.9 15 5.3 4.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Acetyltransf_3 PF13302.1 GAP86717.1 - 1.6e-29 102.9 0.0 1.9e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAP86717.1 - 0.00017 21.5 0.0 0.098 12.6 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family FR47 PF08445.5 GAP86717.1 - 0.14 11.9 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 FR47-like protein GDC-P PF02347.11 GAP86718.1 - 3.3e-177 589.4 0.0 1.2e-158 528.3 0.0 3.0 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.14 GAP86718.1 - 2.5e-08 33.0 0.0 0.00031 19.6 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 GAP86718.1 - 1.5e-07 30.8 0.0 2.8e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Nup54 PF13874.1 GAP86719.1 - 8.7e-43 145.3 0.5 8.7e-43 145.3 0.3 2.8 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 DivIVA PF05103.8 GAP86719.1 - 0.016 15.2 2.2 0.016 15.2 1.6 3.1 2 1 1 3 3 3 0 DivIVA protein Transposase_22 PF02994.9 GAP86719.1 - 0.098 11.1 5.8 0.54 8.7 1.1 2.3 1 1 1 2 2 2 0 L1 transposable element PAT1 PF09770.4 GAP86719.1 - 0.17 10.0 17.8 0.2 9.8 12.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Nucleoporin_FG PF13634.1 GAP86719.1 - 0.48 10.6 37.9 1.2 9.4 26.2 1.6 1 1 0 1 1 1 0 Nucleoporin FG repeat region Spt20 PF12090.3 GAP86719.1 - 8.1 5.7 11.0 1.3 8.3 4.3 1.9 2 1 0 2 2 2 0 Spt20 family CHCH PF06747.8 GAP86720.1 - 2.6e-10 39.9 15.3 1.3e-09 37.7 4.0 2.5 3 0 0 3 3 3 2 CHCH domain Cmc1 PF08583.5 GAP86720.1 - 0.0032 17.1 11.0 0.23 11.2 3.0 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 GAP86720.1 - 0.38 10.8 7.0 2.4 8.2 0.6 2.7 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 UCR_hinge PF02320.11 GAP86720.1 - 3.1 7.8 6.7 4.5 7.2 4.0 2.0 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein COX6B PF02297.12 GAP86720.1 - 3.1 7.8 11.9 8.3 6.5 3.2 2.3 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb CAP PF00188.21 GAP86721.1 - 6.7e-19 68.5 4.8 9.4e-19 68.1 3.3 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DLH PF01738.13 GAP86722.1 - 8.6e-25 87.2 0.0 3e-24 85.5 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 GAP86722.1 - 2.4e-07 30.5 0.0 3.5e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP86722.1 - 5.8e-05 23.0 0.0 0.055 13.3 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family SEP PF08059.8 GAP86722.1 - 0.055 13.7 0.1 0.14 12.4 0.0 1.7 2 0 0 2 2 2 0 SEP domain Peptidase_S9 PF00326.16 GAP86722.1 - 0.057 12.6 0.0 0.088 12.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family peroxidase PF00141.18 GAP86723.1 - 6.8e-16 58.4 0.0 9.8e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 Peroxidase FAA_hydrolase PF01557.13 GAP86724.1 - 9.2e-49 165.8 0.0 1.6e-48 165.0 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 GAP86724.1 - 5.7e-27 93.8 0.0 9.2e-27 93.1 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Fungal_trans PF04082.13 GAP86725.1 - 3e-18 65.6 0.0 3e-18 65.6 0.0 2.3 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP86725.1 - 1.8e-08 34.1 8.0 3.2e-08 33.3 5.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Macoilin PF09726.4 GAP86725.1 - 2.1 6.5 10.8 3 5.9 7.5 1.2 1 0 0 1 1 1 0 Transmembrane protein MAP65_ASE1 PF03999.7 GAP86725.1 - 4.2 5.8 17.5 52 2.2 0.0 2.2 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) Methyltransf_25 PF13649.1 GAP86726.1 - 6.9e-10 39.1 0.1 1.5e-08 34.9 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP86726.1 - 1.3e-08 35.1 0.0 2.5e-07 31.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP86726.1 - 3.6e-05 24.1 0.0 7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP86726.1 - 0.0018 17.9 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP86726.1 - 0.0063 17.0 0.1 0.013 16.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP86726.1 - 0.0083 15.7 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain FAD_binding_3 PF01494.14 GAP86727.1 - 2.7e-13 49.7 3.2 8.2e-05 21.8 0.2 3.0 3 0 0 3 3 3 3 FAD binding domain Pyr_redox PF00070.22 GAP86727.1 - 0.00018 21.8 0.0 0.0018 18.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP86727.1 - 0.0043 17.0 0.0 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 GAP86727.1 - 0.028 14.2 0.2 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding HgmA PF04209.8 GAP86728.1 - 6.2e-174 578.3 0.0 7.1e-174 578.1 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase DPPIV_N PF00930.16 GAP86729.1 - 2.6e-108 361.7 1.1 3.9e-108 361.1 0.8 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 GAP86729.1 - 1.7e-37 128.6 1.5 3.1e-37 127.8 1.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAP86729.1 - 0.00014 21.6 0.0 0.00037 20.2 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP86729.1 - 0.0022 17.9 0.6 0.028 14.3 0.2 2.5 2 1 1 3 3 3 1 Alpha/beta hydrolase family PD40 PF07676.7 GAP86729.1 - 0.087 12.5 4.4 0.62 9.8 0.1 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF3747 PF12565.3 GAP86732.1 - 0.0089 15.1 0.0 0.017 14.1 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3747) vWA-TerF-like PF10138.4 GAP86732.1 - 0.083 12.7 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 vWA found in TerF C terminus PFL PF02901.10 GAP86733.1 - 2e-120 403.1 0.0 3e-120 402.6 0.0 1.1 1 0 0 1 1 1 1 Pyruvate formate lyase Dyp_perox PF04261.7 GAP86733.1 - 8.4e-31 106.8 0.0 1.3e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 Dyp-type peroxidase family Gly_radical PF01228.16 GAP86733.1 - 0.16 12.3 0.0 0.43 10.9 0.0 1.7 1 0 0 1 1 1 0 Glycine radical DUF4126 PF13548.1 GAP86735.1 - 0.076 12.4 2.2 0.11 11.9 1.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4126) Chlorosome_CsmC PF11098.3 GAP86735.1 - 0.14 11.8 8.1 0.19 11.4 5.6 1.2 1 0 0 1 1 1 0 Chlorosome envelope protein C Tape_meas_lam_C PF09718.5 GAP86735.1 - 0.14 12.0 0.9 0.22 11.4 0.4 1.4 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Synuclein PF01387.12 GAP86735.1 - 2 8.3 9.0 8.8 6.2 6.1 1.9 1 1 0 1 1 1 0 Synuclein PGAP1 PF07819.8 GAP86736.1 - 0.0011 18.6 0.1 0.0041 16.7 0.1 1.9 2 1 0 2 2 2 1 PGAP1-like protein Abhydrolase_5 PF12695.2 GAP86736.1 - 0.0028 17.4 0.0 0.0059 16.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP86736.1 - 0.0078 16.1 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 GAP86736.1 - 0.022 14.0 0.0 0.052 12.8 0.0 1.6 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ank_2 PF12796.2 GAP86737.1 - 3e-115 376.8 24.5 2.6e-12 46.9 0.0 12.9 2 2 14 16 16 16 16 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAP86737.1 - 2.2e-66 219.1 24.1 9.8e-09 35.4 0.0 15.6 14 4 3 17 17 17 14 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP86737.1 - 7.1e-65 213.5 25.8 3.8e-07 30.1 0.1 19.4 12 5 8 20 20 20 14 Ankyrin repeats (many copies) Ank PF00023.25 GAP86737.1 - 1.9e-62 204.1 29.5 7.5e-07 28.6 0.0 20.5 21 0 0 21 21 21 13 Ankyrin repeat Ank_3 PF13606.1 GAP86737.1 - 7.6e-50 161.9 19.4 0.0002 21.2 0.0 21.3 23 0 0 23 23 23 11 Ankyrin repeat SPRY PF00622.23 GAP86737.1 - 1.5e-17 63.7 0.1 2.5e-16 59.9 0.1 2.3 2 0 0 2 2 2 1 SPRY domain DUF3659 PF12396.3 GAP86738.1 - 3.1e-147 478.3 87.4 4.5e-23 80.6 0.9 12.9 11 2 0 11 11 11 10 Protein of unknown function (DUF3659) EspB PF05802.6 GAP86738.1 - 0.0057 15.6 11.9 0.015 14.2 8.3 1.7 1 0 0 1 1 1 1 Enterobacterial EspB protein Tape_meas_lam_C PF09718.5 GAP86738.1 - 1.1 9.2 10.6 1.6 8.7 0.4 3.0 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF3659 PF12396.3 GAP86739.1 - 8.3e-16 57.4 6.4 1.1e-09 37.7 4.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3659) FimP PF09766.4 GAP86740.1 - 6.3e-05 22.2 5.7 6.3e-05 22.2 3.9 2.5 2 1 0 2 2 2 1 Fms-interacting protein SOBP PF15279.1 GAP86740.1 - 3.2 8.0 21.8 4.3 7.6 15.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein WD40 PF00400.27 GAP86744.1 - 2.8e-55 182.3 13.5 4.4e-09 35.8 0.1 8.6 9 0 0 9 9 9 7 WD domain, G-beta repeat F-box-like PF12937.2 GAP86744.1 - 1.3e-10 40.8 1.9 1.7e-10 40.4 0.2 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 GAP86744.1 - 2.7e-08 33.2 0.3 2.7e-08 33.2 0.2 2.2 2 1 0 2 2 2 1 F-box domain PQQ_2 PF13360.1 GAP86744.1 - 8.5e-05 22.1 0.3 0.37 10.2 0.0 3.2 3 0 0 3 3 3 2 PQQ-like domain Nup160 PF11715.3 GAP86744.1 - 0.00012 20.3 9.0 0.43 8.6 0.1 5.0 2 2 2 4 4 4 2 Nucleoporin Nup120/160 PRANC PF09372.5 GAP86744.1 - 0.025 14.5 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 PRANC domain DEAD PF00270.24 GAP86745.1 - 1.1e-19 70.5 0.0 6.6e-19 68.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP86745.1 - 6.7e-17 61.1 2.7 1.6e-15 56.7 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAP86745.1 - 8.8e-05 22.4 0.0 0.00021 21.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 GAP86745.1 - 0.00052 18.9 0.0 0.00096 18.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Suf PF05843.9 GAP86745.1 - 0.01 15.6 0.1 0.024 14.3 0.1 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Tyrosinase PF00264.15 GAP86746.1 - 3.8e-46 158.0 2.2 5.4e-46 157.5 1.5 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DiS_P_DiS PF06750.8 GAP86746.1 - 0.00035 20.2 0.0 0.00064 19.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial Peptidase A24 N-terminal domain GST_C PF00043.20 GAP86747.1 - 2.5e-09 37.0 0.0 3.5e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAP86747.1 - 6.8e-09 35.7 0.0 1.1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAP86747.1 - 9.1e-09 35.0 0.4 2.2e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAP86747.1 - 1.6e-08 34.6 0.0 3.2e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAP86747.1 - 2.2e-07 31.2 0.0 3.3e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAP86747.1 - 8.1e-07 28.9 0.0 1.6e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain adh_short PF00106.20 GAP86748.1 - 2.8e-13 50.1 0.0 4.2e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP86748.1 - 3.6e-06 26.7 0.0 6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Phosphoesterase PF04185.9 GAP86749.1 - 7.6e-32 110.9 0.4 2.4e-31 109.3 0.1 1.9 1 1 1 2 2 2 1 Phosphoesterase family Sugar_tr PF00083.19 GAP86750.1 - 4e-83 279.4 15.2 4.6e-83 279.2 10.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP86750.1 - 3.2e-26 91.8 16.9 4.6e-26 91.3 11.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 GAP86750.1 - 0.00017 20.1 4.5 0.00017 20.1 3.1 2.5 2 1 1 3 3 3 1 MFS/sugar transport protein Dynamin_N PF00350.18 GAP86751.1 - 1.6e-18 67.0 0.0 1.7e-17 63.7 0.0 2.3 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 GAP86751.1 - 2.6e-05 23.1 0.1 0.00012 20.9 0.0 2.0 2 0 0 2 2 2 1 Dynamin central region GED PF02212.13 GAP86751.1 - 0.045 13.6 0.6 0.25 11.2 0.0 2.4 2 0 0 2 2 2 0 Dynamin GTPase effector domain Miro PF08477.8 GAP86751.1 - 0.078 13.4 0.1 0.26 11.8 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein CTP_transf_2 PF01467.21 GAP86751.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Cytidylyltransferase PAP2 PF01569.16 GAP86752.1 - 3.1e-23 81.8 0.6 3.1e-23 81.8 0.4 2.1 2 0 0 2 2 2 1 PAP2 superfamily Pox_P21 PF05313.7 GAP86752.1 - 0.026 13.8 0.2 0.05 12.8 0.1 1.4 1 0 0 1 1 1 0 Poxvirus P21 membrane protein DUF3302 PF11742.3 GAP86752.1 - 4.4 7.2 6.5 1.9 8.3 2.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3302) WW PF00397.21 GAP86753.1 - 2.3e-08 33.7 6.4 2.3e-08 33.7 4.5 2.5 2 0 0 2 2 2 1 WW domain FF PF01846.14 GAP86753.1 - 9.4e-08 31.8 0.2 9.4e-08 31.8 0.1 3.3 3 1 0 3 3 3 1 FF domain TTSSLRR PF12468.3 GAP86753.1 - 0.11 12.0 2.5 0.27 10.7 1.7 1.7 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein DLH PF01738.13 GAP86754.1 - 5.2e-27 94.5 0.0 6.3e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 GAP86754.1 - 2.4e-05 24.1 0.0 3.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family TraQ PF09679.5 GAP86755.1 - 0.056 13.3 0.1 0.21 11.5 0.1 1.9 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) Bestrophin PF01062.16 GAP86756.1 - 2.8e-49 167.6 3.0 1.7e-47 161.7 2.1 2.1 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel zf-U1 PF06220.7 GAP86758.1 - 5.2e-07 29.1 0.7 8.2e-07 28.4 0.5 1.3 1 0 0 1 1 1 1 U1 zinc finger PIR PF00399.14 GAP86759.1 - 0.0014 17.9 5.7 0.11 11.8 0.1 3.0 2 0 0 2 2 2 2 Yeast PIR protein repeat SprB PF13573.1 GAP86759.1 - 0.024 14.2 1.3 2.7 7.6 0.0 2.8 2 0 0 2 2 2 0 SprB repeat HEAT_2 PF13646.1 GAP86760.1 - 5.1e-17 61.9 13.7 0.001 19.2 0.1 8.3 4 3 5 9 9 9 7 HEAT repeats HEAT PF02985.17 GAP86760.1 - 7.2e-17 59.9 11.1 0.00036 20.3 0.0 9.9 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.1 GAP86760.1 - 3.7e-15 55.9 25.7 4.5e-07 30.1 0.0 11.8 11 3 3 14 14 13 2 HEAT-like repeat IBN_N PF03810.14 GAP86760.1 - 3.9e-11 42.7 0.1 1.9e-08 34.0 0.0 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 GAP86760.1 - 2.9e-09 37.1 0.3 0.094 13.1 0.0 5.9 4 3 3 7 7 6 2 Vacuolar 14 Fab1-binding region Arm PF00514.18 GAP86760.1 - 8.7e-05 22.1 8.4 2.9 7.8 0.0 7.2 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 GAP86760.1 - 0.00033 20.0 0.1 0.012 14.9 0.0 3.3 3 1 0 3 3 3 1 CLASP N terminal MMS19_C PF12460.3 GAP86760.1 - 0.00091 18.0 9.7 0.01 14.5 0.0 3.9 4 1 1 5 5 5 2 RNAPII transcription regulator C-terminal DUF577 PF04510.7 GAP86760.1 - 0.0019 17.9 0.3 0.038 13.6 0.1 3.0 3 0 0 3 3 3 1 Family of unknown function (DUF577) ParcG PF10274.4 GAP86760.1 - 0.0026 17.6 0.3 0.13 12.1 0.1 3.3 3 1 1 4 4 4 1 Parkin co-regulated protein Vitellogenin_N PF01347.17 GAP86760.1 - 0.008 14.4 0.3 0.024 12.8 0.0 1.9 2 0 0 2 2 2 1 Lipoprotein amino terminal region HEAT_PBS PF03130.11 GAP86760.1 - 0.1 13.1 5.0 22 5.8 0.0 5.1 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat YukD PF08817.5 GAP86760.1 - 0.19 12.3 2.2 29 5.3 0.1 3.8 3 1 1 4 4 4 0 WXG100 protein secretion system (Wss), protein YukD DUF3730 PF12530.3 GAP86760.1 - 0.21 11.4 3.3 0.83 9.5 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3730) IF-2B PF01008.12 GAP86761.1 - 2.1e-24 86.0 0.0 2.7e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.23 GAP86761.1 - 4.7e-10 39.2 0.0 7.6e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Peptidase_M36 PF02128.10 GAP86762.1 - 5.1e-157 522.5 10.1 6.6e-157 522.1 7.0 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 GAP86762.1 - 3.4e-11 42.4 0.5 1.2e-10 40.6 0.2 2.1 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.10 GAP86762.1 - 0.011 15.4 0.1 0.025 14.3 0.1 1.7 1 1 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain GDPD PF03009.12 GAP86762.1 - 0.015 14.8 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Peptidase_MA_2 PF13485.1 GAP86762.1 - 0.037 14.0 2.8 0.25 11.3 0.1 2.5 2 0 0 2 2 2 0 Peptidase MA superfamily AMP-binding PF00501.23 GAP86763.1 - 6.8e-238 788.9 0.0 1.3e-85 287.3 0.0 3.4 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 GAP86763.1 - 1.1e-181 602.3 0.1 2.8e-42 144.6 0.0 6.4 6 0 0 6 6 6 6 Condensation domain PP-binding PF00550.20 GAP86763.1 - 3e-60 200.3 8.5 7e-13 48.6 0.0 7.2 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAP86763.1 - 2.5e-14 53.9 0.0 1.1e-05 26.2 0.0 3.9 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Transferase PF02458.10 GAP86763.1 - 3.8e-06 25.6 0.1 0.2 10.0 0.0 4.7 5 0 0 5 5 5 2 Transferase family AATase PF07247.7 GAP86763.1 - 0.032 12.7 0.6 6.8 5.1 0.0 3.7 3 1 0 3 3 3 0 Alcohol acetyltransferase Glycolipid_bind PF06475.6 GAP86763.1 - 0.28 10.3 0.8 4.6 6.3 0.1 2.4 2 0 0 2 2 2 0 Putative glycolipid-binding K_oxygenase PF13434.1 GAP86764.1 - 3.2e-105 351.8 0.0 2.5e-104 348.8 0.0 1.9 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 GAP86764.1 - 1e-10 42.0 0.0 6.4e-10 39.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAP86764.1 - 1.7e-07 31.1 0.0 4.1e-06 26.6 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 GAP86764.1 - 0.00024 21.0 0.0 0.00077 19.3 0.0 1.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF4147 PF13660.1 GAP86764.1 - 0.053 12.6 0.0 9.1 5.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) F_bP_aldolase PF01116.15 GAP86765.1 - 9.6e-96 320.2 0.0 1.1e-95 320.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II zf-Nse PF11789.3 GAP86767.1 - 7.5e-17 60.5 1.3 1.3e-16 59.8 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 GAP86767.1 - 0.002 17.8 0.8 0.004 16.8 0.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 GAP86767.1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Ring finger domain zf-MIZ PF02891.15 GAP86767.1 - 0.13 11.8 0.7 0.23 11.0 0.5 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger LMBR1 PF04791.11 GAP86767.1 - 1.7 7.1 2.6 2.6 6.5 1.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.1 GAP86767.1 - 2.1 7.2 10.6 4.5 6.1 7.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MR_MLE_C PF13378.1 GAP86769.1 - 7.1e-19 67.8 0.1 2.1e-18 66.3 0.0 1.9 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 GAP86769.1 - 5e-14 52.5 0.7 3.6e-13 49.8 0.1 2.3 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 GAP86769.1 - 0.001 19.0 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 GAP86769.1 - 0.0042 16.0 0.0 0.0063 15.4 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus DAO PF01266.19 GAP86771.1 - 1.4e-43 149.1 0.0 1.8e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 GAP86771.1 - 0.00023 20.1 0.1 0.00088 18.2 0.0 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 GAP86771.1 - 0.00067 19.5 0.0 0.24 11.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP86771.1 - 0.0032 17.4 0.1 0.01 15.8 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAP86771.1 - 0.0062 16.6 0.0 0.014 15.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAP86771.1 - 0.015 15.1 0.0 0.046 13.5 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 GAP86771.1 - 0.095 11.5 0.0 0.45 9.3 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.9 GAP86771.1 - 0.1 11.2 0.0 2.6 6.5 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Ring_hydroxyl_A PF00848.14 GAP86772.1 - 6.3e-35 120.7 2.4 1.8e-34 119.2 1.7 1.8 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 GAP86772.1 - 5.7e-15 54.6 0.0 1.2e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Fungal_trans PF04082.13 GAP86773.1 - 3.7e-13 48.9 2.4 6.7e-13 48.0 1.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP86773.1 - 5.7e-09 35.7 10.3 1.2e-08 34.7 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAO PF01266.19 GAP86774.1 - 6.4e-64 216.1 0.5 9.1e-64 215.6 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T PF01571.16 GAP86774.1 - 8.2e-55 185.4 0.1 1.4e-54 184.6 0.0 1.4 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 GAP86774.1 - 1.1e-16 60.6 0.1 2.7e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pyr_redox PF00070.22 GAP86774.1 - 7.6e-05 23.0 0.8 0.012 15.9 0.2 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP86774.1 - 0.00017 21.7 0.0 0.0012 18.9 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAP86774.1 - 0.00035 19.5 0.1 0.00053 18.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 GAP86774.1 - 0.00076 18.2 0.3 0.045 12.3 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.1 GAP86774.1 - 0.0014 18.4 0.1 0.018 14.7 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding TrkA_N PF02254.13 GAP86774.1 - 0.0042 17.0 0.1 0.011 15.7 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain ThiF PF00899.16 GAP86774.1 - 0.0074 16.1 0.1 0.017 14.9 0.1 1.6 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 GAP86774.1 - 0.026 14.6 0.0 0.052 13.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 GAP86774.1 - 0.027 14.4 0.0 0.075 13.0 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAP86774.1 - 0.055 13.3 0.0 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAP86774.1 - 0.089 11.8 0.1 3 6.7 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain Flavoprotein PF02441.14 GAP86775.1 - 3.2e-16 59.1 0.4 7.2e-16 58.0 0.3 1.7 1 0 0 1 1 1 1 Flavoprotein WD40 PF00400.27 GAP86778.1 - 8.4e-49 161.7 20.2 2.1e-11 43.2 0.1 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 GAP86778.1 - 5.3e-08 32.7 11.9 0.0071 16.0 0.7 4.0 2 2 2 4 4 4 3 Transcription factor IIIC subunit delta N-term ECH PF00378.15 GAP86781.1 - 6.9e-37 126.8 2.6 9.2e-24 83.8 1.1 2.2 1 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 GAP86781.1 - 0.091 12.5 0.1 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 HET PF06985.6 GAP86782.1 - 1.3e-26 93.3 0.1 2.4e-26 92.5 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.20 GAP86782.1 - 5.7e-21 75.1 0.0 9.4e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP86782.1 - 2.4e-16 60.2 0.0 3.5e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP86782.1 - 6.1e-08 32.5 0.0 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 GAP86782.1 - 2.1e-07 30.4 0.0 9e-06 25.0 0.0 2.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 GAP86782.1 - 2.9e-05 24.1 0.0 8.6e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 GAP86782.1 - 0.00093 18.6 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAP86782.1 - 0.062 12.5 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family DFP PF04127.10 GAP86782.1 - 0.21 11.1 0.0 0.84 9.2 0.0 1.9 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein bZIP_1 PF00170.16 GAP86783.1 - 1.8e-12 46.9 5.9 3e-12 46.3 4.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAP86783.1 - 6.3e-06 25.9 9.5 1.1e-05 25.1 6.6 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 GAP86783.1 - 0.052 13.8 3.4 0.11 12.8 2.4 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor TTKRSYEDQ PF10212.4 GAP86783.1 - 0.082 11.8 0.1 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Osmo_CC PF08946.5 GAP86783.1 - 0.16 11.9 1.8 0.31 11.0 1.3 1.3 1 0 0 1 1 1 0 Osmosensory transporter coiled coil ABC_tran PF00005.22 GAP86784.1 - 4.2e-47 159.8 0.1 7.5e-23 81.3 0.0 3.5 3 1 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 GAP86784.1 - 8.8e-19 67.1 6.8 8.8e-19 67.1 4.7 3.6 4 0 0 4 4 4 1 ABC transporter AAA_21 PF13304.1 GAP86784.1 - 1.4e-17 64.5 3.2 0.00011 22.3 0.0 4.7 4 1 1 5 5 5 3 AAA domain SMC_N PF02463.14 GAP86784.1 - 5.5e-11 42.1 3.9 0.0031 16.7 0.0 4.7 5 0 0 5 5 5 4 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 GAP86784.1 - 2.8e-09 37.8 0.2 0.0063 17.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.1 GAP86784.1 - 2.9e-08 33.2 4.5 0.057 12.4 0.0 4.5 4 1 1 5 5 5 2 AAA ATPase domain AAA_29 PF13555.1 GAP86784.1 - 9.4e-07 28.2 0.3 0.016 14.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 GAP86784.1 - 1.2e-06 27.7 0.2 0.029 13.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 GAP86784.1 - 2.5e-06 27.4 0.3 0.0083 16.0 0.0 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 GAP86784.1 - 2.5e-06 27.9 0.2 0.014 15.8 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 GAP86784.1 - 7.7e-06 26.0 0.3 0.37 10.9 0.0 3.3 2 1 0 2 2 2 2 AAA domain MobB PF03205.9 GAP86784.1 - 1.8e-05 24.4 0.4 0.17 11.5 0.2 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 GAP86784.1 - 2.1e-05 24.8 5.1 0.077 13.3 0.0 3.7 5 0 0 5 5 4 2 AAA domain AAA_16 PF13191.1 GAP86784.1 - 2.8e-05 24.1 2.2 0.012 15.6 0.1 3.1 3 0 0 3 3 2 1 AAA ATPase domain AAA PF00004.24 GAP86784.1 - 6.2e-05 23.2 0.0 0.21 11.7 0.1 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 GAP86784.1 - 0.00013 22.3 15.3 0.0067 16.7 0.1 4.3 5 0 0 5 5 4 2 AAA domain AAA_14 PF13173.1 GAP86784.1 - 0.00023 21.0 0.0 0.59 10.0 0.0 3.1 3 0 0 3 3 2 2 AAA domain ArgK PF03308.11 GAP86784.1 - 0.00048 18.9 0.3 0.53 9.0 0.0 2.6 2 0 0 2 2 2 2 ArgK protein NACHT PF05729.7 GAP86784.1 - 0.00053 19.6 0.1 0.81 9.3 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.1 GAP86784.1 - 0.00055 19.8 0.0 1.1 9.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 GAP86784.1 - 0.00081 18.9 0.1 1.3 8.3 0.0 3.0 3 0 0 3 3 3 2 AAA-like domain NTPase_1 PF03266.10 GAP86784.1 - 0.00096 18.9 0.1 0.27 10.9 0.1 2.8 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.17 GAP86784.1 - 0.0021 18.2 0.0 1.8 8.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase SbcCD_C PF13558.1 GAP86784.1 - 0.0023 17.7 1.3 2.1 8.3 0.1 4.0 3 1 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 GAP86784.1 - 0.0031 17.5 4.2 0.33 10.8 0.0 3.0 3 0 0 3 3 2 1 AAA domain cobW PF02492.14 GAP86784.1 - 0.0044 16.4 1.3 1.3 8.4 0.3 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 GAP86784.1 - 0.0065 16.2 0.2 2.5 7.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 GAP86784.1 - 0.0073 15.7 0.3 3.4 7.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 GAP86784.1 - 0.0075 15.7 0.1 1.6 8.1 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.7 GAP86784.1 - 0.011 14.7 1.1 0.25 10.4 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin NB-ARC PF00931.17 GAP86784.1 - 0.02 13.7 0.1 5.6 5.7 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.4 GAP86784.1 - 0.036 13.5 0.2 7.5 6.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 GAP86784.1 - 0.058 12.9 0.2 6.3 6.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 GAP86784.1 - 0.14 11.9 9.6 2.1 8.1 0.5 4.3 3 1 0 3 3 3 0 Dynamin family DUF87 PF01935.12 GAP86784.1 - 0.23 11.2 9.8 0.43 10.3 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function DUF87 GTP_EFTU PF00009.22 GAP86784.1 - 0.72 9.2 4.3 4.7 6.5 0.0 3.5 5 0 0 5 5 3 0 Elongation factor Tu GTP binding domain Tubulin PF00091.20 GAP86788.1 - 6e-70 235.4 0.0 1e-69 234.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 GAP86788.1 - 3.8e-49 165.9 0.1 6.4e-49 165.1 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 GAP86788.1 - 1.3e-05 25.1 0.0 3.1e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 GAP86788.1 - 0.0048 16.3 0.0 0.0086 15.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Pyr_redox_2 PF07992.9 GAP86789.1 - 9.6e-25 87.6 0.0 4.8e-24 85.3 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.17 GAP86789.1 - 7.3e-17 61.1 0.0 3.5e-16 58.9 0.0 2.1 1 1 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Fer2_BFD PF04324.10 GAP86789.1 - 3.7e-15 55.7 3.0 5.7e-12 45.4 2.6 2.7 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske_2 PF13806.1 GAP86789.1 - 6.2e-11 41.9 0.0 0.00024 20.7 0.0 2.7 2 0 0 2 2 2 2 Rieske-like [2Fe-2S] domain Rieske PF00355.21 GAP86789.1 - 4.2e-09 35.8 0.7 1.5e-08 34.0 0.1 2.3 2 1 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.12 GAP86789.1 - 1.6e-07 30.7 0.0 3.1e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox PF00070.22 GAP86789.1 - 8.7e-07 29.2 1.3 0.006 16.9 0.0 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP86789.1 - 0.0032 17.5 0.9 1.6 8.7 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAP86789.1 - 0.073 12.8 2.6 4.5 7.0 0.0 3.2 2 1 1 3 3 3 0 FAD-NAD(P)-binding Pkinase PF00069.20 GAP86790.1 - 2.4e-59 200.6 0.0 3.1e-59 200.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP86790.1 - 4.2e-32 111.2 0.0 5.7e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP86790.1 - 2.9e-05 23.1 0.0 4.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAP86790.1 - 0.0012 18.6 1.3 0.0019 18.0 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 GAP86790.1 - 0.028 13.4 0.0 0.054 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ifi-6-16 PF06140.8 GAP86791.1 - 0.0049 16.6 15.8 0.0078 15.9 11.0 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family E1-E2_ATPase PF00122.15 GAP86791.1 - 0.29 10.1 2.8 0.37 9.7 2.0 1.1 1 0 0 1 1 1 0 E1-E2 ATPase NACHT PF05729.7 GAP86792.1 - 1.7e-09 37.5 0.0 5.3e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAP86792.1 - 1.1e-05 25.5 0.1 0.0023 18.0 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 GAP86792.1 - 0.00021 22.1 1.1 0.0075 17.0 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 GAP86792.1 - 0.0011 18.9 0.4 0.028 14.4 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain Mito_fiss_reg PF05308.6 GAP86792.1 - 0.0059 16.0 0.5 0.01 15.2 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial fission regulator AAA_10 PF12846.2 GAP86792.1 - 0.012 15.0 0.3 0.034 13.5 0.2 1.8 1 0 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.17 GAP86792.1 - 0.12 12.5 0.1 0.51 10.5 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 GAP86792.1 - 0.16 12.1 0.0 2.4 8.3 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Baculo_PEP_C PF04513.7 GAP86792.1 - 0.17 11.7 0.0 9.9 5.9 0.1 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 GAP86792.1 - 0.23 11.7 1.5 8.5 6.7 0.0 3.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MFS_1 PF07690.11 GAP86793.1 - 1.4e-34 119.3 43.8 1.4e-34 119.3 30.4 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAP86793.1 - 2.6e-18 65.5 22.0 3.6e-18 65.0 15.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MRAP PF15183.1 GAP86793.1 - 1 8.9 4.7 2.4 7.8 0.3 2.7 3 0 0 3 3 3 0 Melanocortin-2 receptor accessory protein family PAP1 PF08601.5 GAP86794.1 - 2.6e-61 208.2 19.8 2.6e-61 208.2 13.7 2.9 1 1 2 3 3 1 1 Transcription factor PAP1 bZIP_1 PF00170.16 GAP86794.1 - 4.9e-08 32.7 17.3 1.2e-07 31.6 12.0 1.6 1 1 0 1 1 1 1 bZIP transcription factor Adeno_PIX PF03955.9 GAP86794.1 - 0.00066 20.1 1.2 0.0018 18.7 0.9 1.8 1 0 0 1 1 1 1 Adenovirus hexon-associated protein (IX) DUF812 PF05667.6 GAP86794.1 - 0.0074 14.8 3.1 0.0098 14.4 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF972 PF06156.8 GAP86794.1 - 0.017 15.4 2.1 0.042 14.2 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_Maf PF03131.12 GAP86794.1 - 0.018 15.3 11.3 0.034 14.4 7.8 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.10 GAP86794.1 - 0.019 14.7 17.8 0.081 12.7 12.3 1.9 1 1 0 1 1 1 0 Basic region leucine zipper TBPIP PF07106.8 GAP86794.1 - 0.065 12.7 4.0 0.12 11.9 2.8 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlaC_arch PF05377.6 GAP86794.1 - 0.066 13.1 2.2 0.12 12.2 1.5 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.3 GAP86794.1 - 0.068 12.9 11.5 0.15 11.8 8.0 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ACCA PF03255.9 GAP86794.1 - 0.084 12.4 1.2 0.14 11.7 0.8 1.3 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF3584 PF12128.3 GAP86794.1 - 0.097 9.9 6.1 0.14 9.4 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF904 PF06005.7 GAP86794.1 - 0.18 12.1 6.7 0.41 10.9 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Utp14 PF04615.8 GAP86794.1 - 0.32 9.1 19.4 0.43 8.6 13.4 1.1 1 0 0 1 1 1 0 Utp14 protein Sigma70_ner PF04546.8 GAP86794.1 - 0.36 10.4 10.4 0.8 9.2 7.2 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF4618 PF15397.1 GAP86794.1 - 0.54 9.5 6.2 0.82 8.9 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) IncA PF04156.9 GAP86794.1 - 0.87 9.1 8.1 0.43 10.1 4.1 1.5 2 0 0 2 2 2 0 IncA protein DUF349 PF03993.7 GAP86794.1 - 1.2 9.3 10.5 17 5.6 5.5 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) BSD PF03909.12 GAP86795.1 - 7.3e-15 54.4 0.1 1.4e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 BSD domain BSP_II PF05432.6 GAP86795.1 - 0.0063 15.8 11.4 0.0063 15.8 7.9 3.1 2 1 0 3 3 3 1 Bone sialoprotein II (BSP-II) V-ATPase_G PF03179.10 GAP86795.1 - 1.7 8.9 10.3 0.52 10.6 3.4 2.5 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Suf PF05843.9 GAP86795.1 - 9.2 5.8 11.0 0.65 9.6 3.4 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) WGG PF10273.4 GAP86796.1 - 1.1e-30 105.5 0.3 1.7e-30 104.9 0.2 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Abhydrolase_3 PF07859.8 GAP86797.1 - 5.9e-42 143.6 0.0 1.1e-32 113.4 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 GAP86797.1 - 5.8e-14 51.5 0.0 4.3e-13 48.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 GAP86797.1 - 6.3e-05 22.7 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 GAP86797.1 - 8.6e-05 21.4 0.1 0.03 13.0 0.0 2.2 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_6 PF12697.2 GAP86797.1 - 0.0023 17.8 0.0 0.0055 16.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 GAP86797.1 - 0.048 13.0 0.0 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase MRP-L27 PF09809.4 GAP86798.1 - 2.7e-17 62.3 0.3 3.9e-17 61.9 0.2 1.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 Utp14 PF04615.8 GAP86799.1 - 8.4e-166 553.2 66.6 8.4e-166 553.2 46.2 2.1 1 1 1 2 2 2 1 Utp14 protein DUF1604 PF07713.8 GAP86800.1 - 5.4e-39 131.8 2.7 5.4e-39 131.8 1.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.18 GAP86800.1 - 5.4e-06 26.0 5.5 1.1e-05 25.0 0.8 3.3 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.2 GAP86800.1 - 0.0014 18.4 2.9 0.0033 17.2 0.3 3.0 3 0 0 3 3 3 1 DExH-box splicing factor binding site Glypican PF01153.14 GAP86800.1 - 0.28 9.7 0.2 0.41 9.1 0.2 1.1 1 0 0 1 1 1 0 Glypican HET PF06985.6 GAP86801.1 - 1.8e-48 164.2 0.4 1.6e-26 93.0 0.2 3.8 3 0 0 3 3 3 2 Heterokaryon incompatibility protein (HET) AAA PF00004.24 GAP86804.1 - 0.0023 18.1 0.0 0.0048 17.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PNP_UDP_1 PF01048.15 GAP86805.1 - 4.9e-36 123.8 0.1 6.5e-36 123.4 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily FAD_binding_4 PF01565.18 GAP86806.1 - 9.3e-18 64.0 1.1 1.5e-17 63.3 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP86806.1 - 1.7e-06 27.7 0.5 3.7e-06 26.7 0.4 1.6 1 0 0 1 1 1 1 Berberine and berberine like Atx10homo_assoc PF09759.4 GAP86807.1 - 4e-09 36.1 0.3 1.7e-08 34.1 0.0 2.1 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain ARID PF01388.16 GAP86809.1 - 3.2e-14 52.5 0.0 7.1e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Arm PF00514.18 GAP86809.1 - 0.017 14.9 1.7 0.13 12.1 0.0 2.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat SEN1_N PF12726.2 GAP86809.1 - 0.06 11.3 0.1 0.085 10.9 0.1 1.1 1 0 0 1 1 1 0 SEN1 N terminal KH_1 PF00013.24 GAP86810.1 - 1e-84 278.1 26.0 5.3e-12 45.1 0.1 13.3 14 1 0 14 14 14 10 KH domain KH_3 PF13014.1 GAP86810.1 - 7.7e-63 207.3 18.1 1.1e-09 37.6 0.2 12.0 12 0 0 12 12 12 9 KH domain KH_2 PF07650.12 GAP86810.1 - 7e-10 38.3 22.0 0.0094 15.4 0.4 7.6 7 1 1 8 8 8 5 KH domain SLS PF14611.1 GAP86810.1 - 1.4e-08 34.4 10.3 0.0018 17.7 0.0 6.7 4 2 3 7 7 7 3 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.1 GAP86810.1 - 2.7e-05 23.6 2.5 0.012 15.2 0.1 4.9 5 0 0 5 5 5 1 KH domain Pkinase PF00069.20 GAP86811.1 - 2.6e-69 233.2 0.0 2.6e-69 233.2 0.0 2.5 3 0 0 3 3 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP86811.1 - 1.2e-44 152.3 0.0 1.2e-44 152.3 0.0 2.1 2 0 0 2 2 1 1 Protein tyrosine kinase PBD PF00786.23 GAP86811.1 - 1.3e-14 54.3 0.0 1.3e-14 54.3 0.0 3.9 3 1 0 3 3 2 1 P21-Rho-binding domain OmpH PF03938.9 GAP86811.1 - 2.9e-07 30.5 15.0 2.9e-07 30.5 10.4 3.4 3 0 0 3 3 3 1 Outer membrane protein (OmpH-like) Kinase-like PF14531.1 GAP86811.1 - 1.7e-06 27.1 0.0 1.7e-06 27.1 0.0 1.8 2 0 0 2 2 1 1 Kinase-like Med15 PF09606.5 GAP86811.1 - 9.6e-05 20.7 50.7 9.6e-05 20.7 35.1 3.8 3 1 1 4 4 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Spore_coat_CotO PF14153.1 GAP86811.1 - 0.0011 18.4 13.7 0.0011 18.4 9.5 3.1 3 0 0 3 3 3 1 Spore coat protein CotO DUF3186 PF11382.3 GAP86811.1 - 0.0074 15.4 6.5 0.019 14.0 4.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3186) Ycf1 PF05758.7 GAP86811.1 - 0.036 11.7 12.1 0.0094 13.7 5.2 1.9 2 0 0 2 2 2 0 Ycf1 Cellulose_synt PF03552.9 GAP86811.1 - 2.8 6.1 4.2 4.7 5.3 2.9 1.2 1 0 0 1 1 1 0 Cellulose synthase CDC45 PF02724.9 GAP86811.1 - 3.2 5.6 17.5 0.068 11.1 5.4 2.1 2 0 0 2 2 2 0 CDC45-like protein OATP PF03137.15 GAP86811.1 - 7.9 4.3 15.3 0.023 12.7 3.8 1.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family adh_short PF00106.20 GAP86812.1 - 1e-31 110.1 2.4 1.6e-31 109.4 1.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP86812.1 - 2.3e-26 93.0 0.2 3.1e-26 92.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP86812.1 - 8e-13 48.4 0.5 1.4e-12 47.6 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAP86812.1 - 1.6e-05 24.4 0.2 6.9e-05 22.3 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PA PF02225.17 GAP86812.1 - 0.00044 19.9 0.3 0.0014 18.2 0.2 1.9 1 0 0 1 1 1 1 PA domain Polysacc_synt_2 PF02719.10 GAP86812.1 - 0.02 13.7 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.1 GAP86812.1 - 0.039 14.3 0.0 0.072 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_31 PF01055.21 GAP86814.1 - 6e-110 368.1 0.1 7.3e-110 367.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 GAP86814.1 - 1.5e-15 56.7 0.0 5.9e-15 54.8 0.0 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like Glyco_hydro_3 PF00933.16 GAP86815.1 - 3.8e-66 223.0 0.0 5e-66 222.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAP86815.1 - 3.9e-59 199.9 0.0 6e-59 199.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAP86815.1 - 2.9e-23 81.5 1.5 3.9e-23 81.1 0.2 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain DUF11 PF01345.13 GAP86815.1 - 0.00077 19.4 3.9 0.00077 19.4 2.7 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF11 Sugar-bind PF04198.8 GAP86815.1 - 0.034 13.0 0.0 0.063 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain CARDB PF07705.6 GAP86815.1 - 0.048 13.7 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 CARDB Phage_antiter_Q PF06323.6 GAP86815.1 - 0.18 11.1 0.2 14 4.9 0.0 2.3 2 0 0 2 2 2 0 Phage antitermination protein Q UQ_con PF00179.21 GAP86816.1 - 5.5e-15 55.0 0.0 6e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Complex1_LYR PF05347.10 GAP86817.1 - 2e-06 27.5 0.0 4.2e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAP86817.1 - 1.2e-05 25.4 0.0 3.3e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Complex1_LYR-like SlyX PF04102.7 GAP86817.1 - 0.31 11.4 4.6 0.67 10.3 0.6 2.4 2 0 0 2 2 2 0 SlyX bZIP_1 PF00170.16 GAP86818.1 - 4.5e-06 26.5 0.9 1e-05 25.4 0.7 1.6 1 0 0 1 1 1 1 bZIP transcription factor TMEM51 PF15345.1 GAP86818.1 - 0.31 10.6 18.3 2.6 7.6 0.1 3.6 3 0 0 3 3 3 0 Transmembrane protein 51 Spt20 PF12090.3 GAP86818.1 - 5 6.4 21.5 1.7 7.9 0.0 3.0 3 0 0 3 3 3 0 Spt20 family FAD_binding_3 PF01494.14 GAP86819.1 - 2.1e-21 76.3 0.5 2.9e-17 62.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAP86819.1 - 5.9e-07 28.7 1.2 0.0094 14.8 0.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.5 GAP86819.1 - 6.9e-05 21.8 0.0 0.29 9.9 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase NAD_binding_8 PF13450.1 GAP86819.1 - 8.9e-05 22.4 0.0 0.00024 21.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 GAP86819.1 - 0.0002 20.1 0.1 0.43 9.1 0.0 2.8 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox_2 PF07992.9 GAP86819.1 - 0.00087 19.2 0.4 0.0016 18.3 0.3 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAP86819.1 - 0.0011 17.9 0.1 0.0019 17.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 GAP86819.1 - 0.0063 15.0 0.1 0.01 14.3 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 GAP86819.1 - 0.03 14.3 0.0 0.067 13.2 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAP86819.1 - 0.065 12.1 0.6 2.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 GAP86819.1 - 0.07 12.6 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 GAP86819.1 - 0.11 12.2 1.4 8 6.2 0.1 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 GAP86819.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 GAP86819.1 - 0.14 12.6 0.2 0.32 11.4 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CRAL_TRIO PF00650.15 GAP86820.1 - 6e-24 84.3 0.0 7.6e-24 83.9 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAP86820.1 - 0.00099 19.1 0.0 0.0029 17.6 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Peptidase_M54 PF07998.6 GAP86821.1 - 3.2e-11 43.3 0.0 8.1e-11 42.0 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M54 DUF1025 PF06262.6 GAP86821.1 - 0.0038 16.9 0.0 0.0086 15.8 0.0 1.5 1 0 0 1 1 1 1 Possibl zinc metallo-peptidase Endonuclease_1 PF04231.8 GAP86821.1 - 0.0077 16.0 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease I Reprolysin PF01421.14 GAP86821.1 - 0.017 14.7 0.1 0.034 13.7 0.0 1.5 2 0 0 2 2 2 0 Reprolysin (M12B) family zinc metalloprotease Reprolysin_2 PF13574.1 GAP86821.1 - 0.021 14.8 0.1 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 GAP86821.1 - 0.034 14.6 0.0 0.098 13.1 0.0 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 GAP86821.1 - 0.15 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Matrixin Metallopep PF12044.3 GAP86821.1 - 0.17 10.2 0.4 0.26 9.6 0.3 1.1 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M57 PF12388.3 GAP86821.1 - 0.18 11.0 0.3 0.3 10.3 0.2 1.2 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase MCE PF02470.15 GAP86823.1 - 0.16 12.0 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 mce related protein Chal_sti_synt_N PF00195.14 GAP86825.1 - 3.8e-17 62.2 0.0 3.8e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain FAE1_CUT1_RppA PF08392.7 GAP86825.1 - 2.2e-06 26.9 0.0 2.5e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ketoacyl-synt PF00109.21 GAP86825.1 - 0.08 12.3 1.0 0.35 10.3 0.7 2.0 1 1 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Chal_sti_synt_C PF02797.10 GAP86826.1 - 5.8e-07 29.5 0.0 6.6e-05 22.8 0.0 2.2 1 1 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Asparaginase_2 PF01112.13 GAP86827.1 - 1.1e-83 280.6 0.5 1.4e-83 280.3 0.3 1.0 1 0 0 1 1 1 1 Asparaginase Pectate_lyase_3 PF12708.2 GAP86828.1 - 1.7e-85 286.6 27.3 1.7e-65 221.3 6.6 3.4 3 1 1 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 GAP86828.1 - 1.4e-06 27.6 3.1 0.0063 15.9 0.2 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase E1-E2_ATPase PF00122.15 GAP86829.1 - 2.1e-58 197.0 1.1 4.3e-58 196.0 0.8 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAP86829.1 - 2e-26 92.6 9.1 2e-26 92.6 6.3 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAP86829.1 - 1.8e-21 77.5 0.1 3.8e-21 76.5 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAP86829.1 - 6.6e-18 63.9 0.1 6.6e-18 63.9 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 GAP86829.1 - 9.4e-09 35.7 0.6 9.5e-08 32.4 0.0 3.0 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAP86829.1 - 0.00011 21.9 0.2 0.00028 20.5 0.2 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_19 PF13245.1 GAP86829.1 - 0.035 13.8 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Glyco_hydro_61 PF03443.9 GAP86830.1 - 4.9e-60 203.0 0.1 6.6e-60 202.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.11 GAP86831.1 - 4.8e-28 97.8 31.1 4.8e-28 97.8 21.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily HTH_psq PF05225.11 GAP86831.1 - 1.1e-17 63.2 0.4 1.8e-08 33.8 0.0 2.8 3 0 0 3 3 3 2 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 GAP86831.1 - 7.2e-07 28.9 0.3 1.7e-06 27.7 0.2 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_28 PF13518.1 GAP86831.1 - 0.0043 17.0 0.3 1.7 8.7 0.0 3.3 3 0 0 3 3 3 2 Helix-turn-helix domain Pam16 PF03656.8 GAP86832.1 - 4.1e-33 113.8 0.2 5e-33 113.5 0.1 1.0 1 0 0 1 1 1 1 Pam16 Phasin_2 PF09361.5 GAP86832.1 - 0.011 15.7 0.3 0.054 13.5 0.0 2.2 2 1 0 2 2 2 0 Phasin protein DUF3644 PF12358.3 GAP86832.1 - 0.051 13.8 0.0 0.093 13.0 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3644) DUF2884 PF11101.3 GAP86832.1 - 0.08 12.3 0.1 0.095 12.0 0.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) BPL_N PF09825.4 GAP86833.1 - 6.6e-140 466.0 0.0 8e-140 465.7 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 GAP86833.1 - 6e-22 77.9 0.0 9.9e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF2757 PF10955.3 GAP86833.1 - 0.082 13.1 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) Mgm101p PF06420.7 GAP86834.1 - 1.9e-89 297.4 0.0 2.4e-89 297.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 TB2_DP1_HVA22 PF03134.14 GAP86835.1 - 7.3e-28 96.1 7.1 1e-27 95.7 4.9 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF4407 PF14362.1 GAP86835.1 - 0.058 12.3 0.4 0.078 11.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GFA PF04828.9 GAP86836.1 - 4e-22 77.9 0.1 6.8e-22 77.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme RNA_POL_M_15KD PF02150.11 GAP86836.1 - 0.026 14.2 0.6 0.065 12.9 0.0 1.9 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Flavi_NS1 PF00948.16 GAP86836.1 - 0.086 11.2 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Flavivirus non-structural Protein NS1 HET PF06985.6 GAP86837.1 - 1.6e-28 99.5 0.0 2.5e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Velvet PF11754.3 GAP86838.1 - 8.1e-46 156.1 0.4 2.1e-45 154.8 0.3 1.7 1 1 0 1 1 1 1 Velvet factor GST_C_3 PF14497.1 GAP86840.1 - 2.7e-07 30.9 0.0 6.1e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAP86840.1 - 0.0013 18.6 1.2 0.0031 17.3 0.8 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAP86840.1 - 0.02 15.1 0.0 0.077 13.2 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF3437 PF11919.3 GAP86841.1 - 1.1e-31 108.3 0.0 3.1e-31 106.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 GAP86841.1 - 0.0049 16.8 0.1 56 4.2 0.0 5.5 6 0 0 6 6 6 0 HEAT repeat WAC_Acf1_DNA_bd PF10537.4 GAP86841.1 - 0.063 13.4 0.0 0.31 11.2 0.0 2.2 2 0 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal MFS_1 PF07690.11 GAP86843.1 - 1.6e-07 30.3 31.7 4.5e-07 28.8 21.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily PRRSV_2b PF07069.6 GAP86843.1 - 6.9 7.0 7.4 2.5 8.4 0.7 2.5 2 0 0 2 2 2 0 Porcine reproductive and respiratory syndrome virus 2b MFS_1 PF07690.11 GAP86844.1 - 5.9e-11 41.6 10.2 7.2e-11 41.3 7.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP86844.1 - 6.7e-05 21.6 0.0 6.7e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1228 PF06779.9 GAP86844.1 - 0.0037 17.2 1.1 0.0076 16.2 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1228) MFS_2 PF13347.1 GAP86844.1 - 0.0061 15.0 0.2 0.0069 14.8 0.1 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein DUF791 PF05631.9 GAP86844.1 - 0.0093 14.6 0.2 0.013 14.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF791) Mannosyl_trans2 PF04188.8 GAP86846.1 - 3.5e-66 223.9 5.0 5.3e-66 223.3 3.5 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) Nuc_sug_transp PF04142.10 GAP86848.1 - 7.4e-74 247.9 7.6 1.1e-73 247.3 5.2 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 GAP86848.1 - 2e-07 30.7 22.9 1.1e-05 25.0 2.0 2.5 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 GAP86848.1 - 6e-07 28.6 10.5 0.0016 17.3 0.5 2.2 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 GAP86848.1 - 1.4e-05 25.1 26.0 6.9e-05 22.8 3.7 2.6 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 GAP86848.1 - 0.00019 21.5 1.2 0.00019 21.5 0.8 2.7 3 0 0 3 3 3 1 Multidrug resistance efflux transporter Ni_hydr_CYTB PF01292.15 GAP86848.1 - 0.091 12.1 0.1 0.091 12.1 0.0 2.4 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 Sec63 PF02889.11 GAP86849.1 - 1.6e-41 142.6 0.0 2.4e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 GAP86849.1 - 3.1e-26 91.8 0.0 6.4e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP86849.1 - 1.7e-09 37.3 0.0 4.6e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAP86849.1 - 5e-09 36.2 0.0 1e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 GAP86849.1 - 0.00062 19.9 0.0 0.0017 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 GAP86849.1 - 0.033 13.0 0.0 0.1 11.4 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein UvrD-helicase PF00580.16 GAP86849.1 - 0.082 12.1 0.1 0.27 10.4 0.0 1.8 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_10 PF12846.2 GAP86849.1 - 0.097 12.0 0.1 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_19 PF13245.1 GAP86849.1 - 0.097 12.4 0.0 0.49 10.1 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain HHH_5 PF14520.1 GAP86849.1 - 0.14 12.3 0.0 0.49 10.6 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain Oxidored_FMN PF00724.15 GAP86850.1 - 8.5e-49 166.3 0.0 1.1e-48 166.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family 2OG-FeII_Oxy_3 PF13640.1 GAP86851.1 - 5.7e-12 46.0 0.0 1.8e-11 44.3 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 GAP86851.1 - 4.2e-05 23.0 0.2 0.00011 21.7 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 GAP86851.1 - 0.029 14.6 0.0 0.053 13.8 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Aha1_N PF09229.6 GAP86852.1 - 9e-35 119.4 0.2 1.3e-34 118.9 0.1 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 GAP86852.1 - 2.8e-17 62.9 1.8 2.9e-17 62.8 0.4 1.7 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein DUF4162 PF13732.1 GAP86852.1 - 0.073 13.5 0.7 0.53 10.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) Sugar_tr PF00083.19 GAP86853.1 - 5.7e-79 265.8 19.3 7.2e-79 265.4 13.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP86853.1 - 1.3e-35 122.7 45.3 5.4e-31 107.5 17.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAP86853.1 - 0.00013 20.2 3.2 0.00027 19.3 2.2 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LacY_symp PF01306.14 GAP86853.1 - 0.0035 15.9 14.7 0.019 13.5 3.0 2.2 2 0 0 2 2 2 2 LacY proton/sugar symporter Glyco_hydro_2_C PF02836.12 GAP86854.1 - 2.6e-96 322.0 0.0 3.6e-96 321.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 GAP86854.1 - 3.2e-55 187.1 0.0 4.6e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 GAP86854.1 - 3e-51 173.2 0.2 5.6e-51 172.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 GAP86854.1 - 7.4e-09 36.0 0.1 5.1e-08 33.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 GAP86854.1 - 0.054 13.7 0.0 0.19 12.0 0.0 1.9 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Pec_lyase_C PF00544.14 GAP86855.1 - 4.3e-43 147.1 10.1 5.9e-43 146.6 7.0 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 GAP86855.1 - 9e-05 22.2 18.8 0.0033 17.2 13.0 2.3 1 1 0 1 1 1 1 Right handed beta helix region Alpha_kinase PF02816.13 GAP86856.1 - 2.6e-44 151.1 0.0 3.8e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.1 GAP86856.1 - 6.8e-08 32.8 0.1 1.6e-07 31.5 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 GAP86856.1 - 0.00015 21.5 0.0 0.00025 20.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain APH PF01636.18 GAP86859.1 - 4.4e-07 29.8 0.0 7.2e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 GAP86859.1 - 0.24 9.9 0.0 0.34 9.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Ank_2 PF12796.2 GAP86860.1 - 1.4e-28 99.0 5.2 0.00032 20.9 0.2 10.3 6 3 3 9 9 9 7 Ankyrin repeats (3 copies) Ank PF00023.25 GAP86860.1 - 5.5e-13 48.0 8.9 1.8 8.5 0.0 12.7 14 3 1 15 15 15 3 Ankyrin repeat Ank_3 PF13606.1 GAP86860.1 - 5.1e-08 32.4 8.6 68 4.1 0.0 12.3 15 1 1 16 16 16 0 Ankyrin repeat Ank_5 PF13857.1 GAP86860.1 - 1.7e-07 31.2 7.2 5.7 7.3 0.0 9.7 10 2 2 12 12 12 1 Ankyrin repeats (many copies) DUF2893 PF11459.3 GAP86860.1 - 0.00074 19.2 0.1 0.005 16.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknwon function (DUF2893) Ank_4 PF13637.1 GAP86860.1 - 0.0015 18.9 16.2 8.9 6.9 0.1 9.8 12 1 1 13 13 13 1 Ankyrin repeats (many copies) Peptidase_M4_C PF02868.10 GAP86861.1 - 4.3e-46 156.6 0.0 8.4e-46 155.6 0.0 1.5 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.13 GAP86861.1 - 1.7e-27 96.3 3.2 2.8e-27 95.7 2.2 1.4 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain Peptidase_M13 PF01431.16 GAP86861.1 - 0.0042 16.2 0.9 0.0075 15.4 0.1 1.8 2 0 0 2 2 2 1 Peptidase family M13 Senescence PF06911.7 GAP86861.1 - 0.064 12.9 0.5 14 5.3 0.0 2.6 3 0 0 3 3 3 0 Senescence-associated protein MFS_1 PF07690.11 GAP86862.1 - 3.9e-07 29.1 26.2 1.9e-06 26.8 18.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAP86862.1 - 2.5e-06 25.9 0.5 3.7e-06 25.4 0.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAP86862.1 - 0.49 8.9 8.4 0.016 13.8 0.9 2.0 2 1 0 2 2 2 0 Sugar (and other) transporter AAA_12 PF13087.1 GAP86863.1 - 5.3e-39 133.6 0.0 9.7e-39 132.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAP86863.1 - 3.7e-24 85.5 0.2 8.8e-24 84.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAP86863.1 - 1.1e-08 34.7 0.0 3.8e-08 32.9 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 GAP86863.1 - 1.7e-05 23.9 0.1 0.11 11.4 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 GAP86863.1 - 2.4e-05 24.4 1.9 6.1e-05 23.0 0.4 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.1 GAP86863.1 - 3.5e-05 23.4 0.0 0.0027 17.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain XdhC_C PF13478.1 GAP86863.1 - 0.00075 19.8 0.0 2.8 8.2 0.0 3.3 3 0 0 3 3 3 2 XdhC Rossmann domain Viral_helicase1 PF01443.13 GAP86863.1 - 0.0016 18.0 0.5 0.11 11.9 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase zf-CCCH PF00642.19 GAP86863.1 - 0.0022 17.6 5.1 0.0058 16.2 3.5 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) UvrD_C_2 PF13538.1 GAP86863.1 - 0.051 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 GAP86863.1 - 0.081 13.0 0.1 0.68 10.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain Spc24 PF08286.6 GAP86865.1 - 5.4e-37 126.0 0.0 1.4e-34 118.3 0.0 2.1 1 1 1 2 2 2 2 Spc24 subunit of Ndc80 DUF3584 PF12128.3 GAP86865.1 - 0.076 10.3 8.9 0.097 9.9 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) L31 PF09784.4 GAP86865.1 - 0.13 12.3 0.4 0.21 11.6 0.3 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 TPR_MLP1_2 PF07926.7 GAP86865.1 - 0.23 11.1 5.1 0.43 10.3 3.5 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.15 GAP86865.1 - 0.62 9.8 5.3 1.4 8.6 0.8 2.3 1 1 1 2 2 2 0 Prefoldin subunit EAP30 PF04157.11 GAP86865.1 - 1.2 8.2 6.0 6.7 5.7 4.8 1.7 1 1 1 2 2 2 0 EAP30/Vps36 family Viral_P18 PF04521.8 GAP86865.1 - 3 7.3 5.5 2.8 7.4 1.4 2.2 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Fis1_TPR_C PF14853.1 GAP86866.1 - 2.3e-26 91.4 1.9 4.5e-26 90.4 1.3 1.5 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 GAP86866.1 - 1.4e-16 59.4 0.0 2.3e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_16 PF13432.1 GAP86866.1 - 0.0026 18.3 0.1 0.0048 17.5 0.1 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAP86866.1 - 0.0049 16.6 2.2 0.0093 15.8 1.5 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat zf-RING_2 PF13639.1 GAP86867.1 - 1.1e-15 57.1 6.1 1.1e-15 57.1 4.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 GAP86867.1 - 1.2e-09 37.7 10.1 1.5e-09 37.3 1.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAP86867.1 - 3.1e-08 33.6 2.1 3.1e-08 33.6 1.5 2.2 3 0 0 3 3 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 GAP86867.1 - 3.6e-07 30.1 6.8 3.6e-07 30.1 4.7 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAP86867.1 - 5.6e-06 25.9 3.5 5.6e-06 25.9 2.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 GAP86867.1 - 2.4e-05 23.8 5.0 2.4e-05 23.8 3.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAP86867.1 - 0.00034 20.3 1.9 0.00034 20.3 1.3 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 GAP86867.1 - 0.036 13.5 1.8 0.072 12.6 1.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Baculo_RING PF05883.6 GAP86867.1 - 0.14 11.9 2.5 0.11 12.3 0.4 1.7 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain Prok-RING_1 PF14446.1 GAP86867.1 - 0.28 10.9 8.4 22 4.8 0.0 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 PHD PF00628.24 GAP86867.1 - 1.4 8.6 16.5 0.16 11.7 3.7 2.7 2 1 0 2 2 2 0 PHD-finger PBP1_TM PF14812.1 GAP86868.1 - 0.21 11.9 7.3 6.2 7.2 0.1 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Macoilin PF09726.4 GAP86868.1 - 1 7.5 9.4 1.4 7.0 6.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Fungal_trans PF04082.13 GAP86869.1 - 5.1e-25 87.8 1.6 7.9e-25 87.1 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP86869.1 - 5.1e-08 32.6 9.9 1.1e-07 31.6 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyridox_oxase_2 PF12766.2 GAP86871.1 - 6.8e-17 61.6 0.0 7.6e-15 55.0 0.0 3.0 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CPSase_L_D2 PF02786.12 GAP86872.1 - 8.6e-113 374.7 0.2 7e-83 277.0 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 GAP86872.1 - 7e-44 148.5 0.0 1.6e-43 147.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.16 GAP86872.1 - 6.2e-42 142.6 0.0 1.3e-41 141.5 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.23 GAP86872.1 - 2.1e-41 141.5 0.0 5.3e-41 140.1 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_chain PF00289.17 GAP86872.1 - 1.2e-40 138.0 0.0 5.2e-20 71.5 0.0 2.9 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 GAP86872.1 - 2.9e-40 136.8 0.0 7.1e-40 135.5 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 GAP86872.1 - 1.1e-35 122.9 0.2 3.9e-23 82.1 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 GAP86872.1 - 1.5e-34 119.1 0.0 3.5e-34 117.9 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATPgrasp_Ter PF15632.1 GAP86872.1 - 9.7e-23 80.4 0.1 9.7e-13 47.5 0.0 3.8 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 GAP86872.1 - 1.7e-21 75.9 0.0 9.6e-21 73.5 0.0 2.4 2 0 0 2 2 2 1 MGS-like domain ATP-grasp PF02222.17 GAP86872.1 - 1.9e-16 59.9 0.2 1e-08 34.7 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 GAP86872.1 - 5e-14 52.1 0.8 1.4e-06 27.8 0.1 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 GAP86872.1 - 1.9e-06 27.8 0.6 0.016 15.0 0.1 2.9 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 GAP86872.1 - 1.7e-05 24.3 0.4 0.00037 19.9 0.2 2.4 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 GAP86872.1 - 9.8e-05 21.8 0.0 0.00022 20.6 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family GARS_A PF01071.14 GAP86872.1 - 0.041 13.4 0.2 3 7.3 0.0 2.8 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TrkA_N PF02254.13 GAP86872.1 - 0.073 13.0 0.0 0.58 10.1 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain Nipped-B_C PF12830.2 GAP86875.1 - 3e-42 144.3 2.6 1.1e-40 139.2 1.5 3.2 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 GAP86875.1 - 1.4e-11 44.1 2.3 9.3e-11 41.4 0.2 3.2 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 GAP86875.1 - 1.1e-05 25.1 1.0 0.0081 16.1 0.0 4.3 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.2 GAP86875.1 - 0.0002 21.2 1.8 0.0082 16.0 0.0 3.6 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 GAP86875.1 - 0.0082 16.4 0.1 0.09 13.0 0.0 3.0 2 1 0 2 2 2 1 HEAT repeats TFIIS_C PF01096.13 GAP86876.1 - 9.3e-15 53.9 0.6 9.3e-15 53.9 0.4 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 GAP86876.1 - 0.00019 21.0 7.8 0.0003 20.4 2.3 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit C1_1 PF00130.17 GAP86876.1 - 0.0095 15.6 2.8 0.029 14.0 0.5 2.2 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) A2L_zn_ribbon PF08792.5 GAP86876.1 - 0.55 9.7 0.1 0.55 9.7 0.1 3.3 4 0 0 4 4 4 0 A2L zinc ribbon domain OrfB_Zn_ribbon PF07282.6 GAP86876.1 - 0.6 9.8 8.8 2.1 8.0 0.7 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain DZR PF12773.2 GAP86876.1 - 0.9 9.4 9.5 0.39 10.5 0.8 2.6 2 1 1 3 3 3 0 Double zinc ribbon GFA PF04828.9 GAP86876.1 - 1.1 9.2 5.8 7.8 6.5 1.9 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme IBR PF01485.16 GAP86876.1 - 1.7 8.5 8.8 2.3 8.1 0.5 2.7 2 1 0 2 2 2 0 IBR domain Lar_restr_allev PF14354.1 GAP86876.1 - 2 8.7 10.9 2.7 8.3 0.3 3.1 2 1 0 2 2 2 0 Restriction alleviation protein Lar HypA PF01155.14 GAP86876.1 - 2.3 7.9 7.3 2.5 7.8 0.5 2.4 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family HEAT_2 PF13646.1 GAP86877.1 - 4.6e-29 100.5 6.7 2.2e-14 53.5 0.1 3.7 2 2 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.11 GAP86877.1 - 1.8e-18 65.0 4.3 0.0044 17.3 0.0 6.4 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 GAP86877.1 - 1.5e-06 28.5 10.3 0.032 14.7 0.0 4.9 2 2 2 4 4 4 3 HEAT-like repeat HEAT PF02985.17 GAP86877.1 - 0.00012 21.8 6.2 4.9 7.4 0.0 5.9 7 0 0 7 7 7 3 HEAT repeat PNPOx_C PF10590.4 GAP86878.1 - 1.8e-21 75.3 1.2 1.8e-21 75.3 0.8 2.3 2 1 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 GAP86878.1 - 9.1e-19 67.2 0.0 1.8e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 GAP86878.1 - 0.022 15.0 0.0 0.047 14.0 0.0 1.6 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase adh_short PF00106.20 GAP86879.1 - 2.3e-28 99.2 0.7 3.1e-28 98.7 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP86879.1 - 2.8e-23 82.9 0.0 3.7e-23 82.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP86879.1 - 1.3e-14 54.2 0.2 1.8e-14 53.8 0.2 1.1 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.21 GAP86879.1 - 0.0082 15.6 1.7 1.1 8.7 0.3 2.3 1 1 1 2 2 2 2 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.14 GAP86879.1 - 0.028 13.4 0.0 0.061 12.4 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 GAP86879.1 - 0.032 14.2 0.7 0.046 13.7 0.5 1.5 1 1 0 1 1 1 0 NADH(P)-binding DUF1372 PF07116.6 GAP86879.1 - 0.045 13.7 0.3 0.14 12.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1372) Epimerase PF01370.16 GAP86879.1 - 0.05 13.0 0.1 0.082 12.3 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 GAP86879.1 - 0.07 12.2 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 GAP86879.1 - 0.083 13.3 0.4 0.16 12.4 0.3 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AAA PF00004.24 GAP86880.1 - 1.1e-15 58.0 0.0 2e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 GAP86880.1 - 0.00034 20.9 0.0 0.00084 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zot PF05707.7 GAP86880.1 - 0.00045 19.7 0.0 0.0021 17.5 0.0 1.9 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_16 PF13191.1 GAP86880.1 - 0.0031 17.5 0.8 0.012 15.6 0.3 2.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 GAP86880.1 - 0.0096 16.7 1.2 0.037 14.8 0.2 2.7 3 1 0 3 3 2 1 AAA domain AAA_19 PF13245.1 GAP86880.1 - 0.013 15.2 0.1 0.033 13.9 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain Torsin PF06309.6 GAP86880.1 - 0.03 14.2 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_22 PF13401.1 GAP86880.1 - 0.031 14.3 0.4 0.22 11.6 0.3 2.3 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 GAP86880.1 - 0.052 12.6 0.2 0.11 11.6 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 GAP86880.1 - 0.096 12.5 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 GAP86880.1 - 0.12 11.3 0.4 0.28 10.1 0.3 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RuvB_N PF05496.7 GAP86880.1 - 0.16 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF1308 PF07000.6 GAP86881.1 - 2.4e-39 135.0 0.0 3e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) Cutinase PF01083.17 GAP86882.1 - 4.3e-42 143.8 3.0 5.3e-42 143.5 2.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 GAP86882.1 - 0.00082 18.8 0.1 0.0015 17.9 0.1 1.4 1 0 0 1 1 1 1 PE-PPE domain Peptidase_C25_C PF03785.9 GAP86882.1 - 0.06 13.1 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Peptidase family C25, C terminal ig-like domain AAA_19 PF13245.1 GAP86882.1 - 0.066 12.9 0.7 0.13 12.0 0.5 1.5 1 0 0 1 1 1 0 Part of AAA domain Bacteriocin_IId PF09221.5 GAP86882.1 - 0.61 10.0 4.5 0.16 11.9 0.6 1.9 2 0 0 2 2 2 0 Bacteriocin class IId cyclical uberolysin-like Glyco_hydro_18 PF00704.23 GAP86883.1 - 1e-16 61.3 0.0 4e-16 59.4 0.0 1.7 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 Aldo_ket_red PF00248.16 GAP86884.1 - 1.7e-41 141.9 0.0 2e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family FIST_C PF10442.4 GAP86885.1 - 0.092 12.6 0.0 0.14 12.1 0.0 1.3 1 1 0 1 1 1 0 FIST C domain p450 PF00067.17 GAP86887.1 - 1.5e-56 191.8 0.0 2e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 GAP86888.1 - 1.8e-18 67.0 0.6 2.6e-18 66.5 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP86888.1 - 8.3e-07 28.8 0.3 1.1e-06 28.4 0.2 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAP86888.1 - 5e-05 23.1 0.0 0.00013 21.8 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 GAP86888.1 - 0.071 12.2 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) FAD_binding_4 PF01565.18 GAP86889.1 - 5.3e-20 71.3 3.8 1.7e-19 69.7 2.6 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP86889.1 - 1.9e-08 34.0 0.2 4.4e-08 32.9 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like Abhydrolase_6 PF12697.2 GAP86890.1 - 2.3e-19 70.1 0.4 3e-19 69.8 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP86890.1 - 1.7e-16 60.2 0.0 2.6e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAP86890.1 - 5.4e-08 32.3 0.0 8.8e-06 25.0 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 GAP86890.1 - 2e-07 30.7 0.0 2.9e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 GAP86890.1 - 2.5e-05 22.9 0.0 0.00015 20.3 0.0 2.0 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) DUF1100 PF06500.6 GAP86890.1 - 7.7e-05 21.4 0.0 0.00084 18.0 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) BAAT_C PF08840.6 GAP86890.1 - 0.0001 22.1 0.0 0.00099 18.8 0.0 2.0 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal LIP PF03583.9 GAP86890.1 - 0.13 11.4 0.0 2.6 7.1 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase Esterase PF00756.15 GAP86890.1 - 0.14 11.5 0.0 0.39 10.1 0.0 1.8 2 1 0 2 2 2 0 Putative esterase DLH PF01738.13 GAP86890.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family ketoacyl-synt PF00109.21 GAP86891.1 - 1.5e-65 221.2 0.1 2.8e-65 220.3 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAP86891.1 - 2e-57 194.9 0.0 3.5e-57 194.1 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 GAP86891.1 - 7e-55 186.2 0.0 1.1e-54 185.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 GAP86891.1 - 7.3e-54 182.1 0.0 1.8e-53 180.9 0.0 1.7 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 GAP86891.1 - 3.1e-37 128.0 0.0 8.8e-37 126.5 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAP86891.1 - 7.8e-35 119.3 2.7 2.3e-34 117.7 1.9 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 GAP86891.1 - 4.6e-18 65.0 0.0 1.4e-17 63.4 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAP86891.1 - 2.3e-11 44.7 0.0 9.5e-11 42.6 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP86891.1 - 1.3e-06 28.0 0.1 3.7e-06 26.6 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 GAP86891.1 - 1.1e-05 25.6 0.1 2.6e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 GAP86891.1 - 0.011 14.7 0.1 0.021 13.7 0.1 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain HNH_2 PF13391.1 GAP86892.1 - 6.8e-09 35.3 0.3 1.9e-08 33.9 0.2 1.8 1 0 0 1 1 1 1 HNH endonuclease Nop14 PF04147.7 GAP86892.1 - 6 4.6 9.8 8.3 4.1 6.8 1.0 1 0 0 1 1 1 0 Nop14-like family TRP PF06011.7 GAP86893.1 - 2.5e-137 458.0 28.3 3.2e-137 457.6 19.6 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 GAP86893.1 - 1.3e-34 119.2 0.1 2.1e-34 118.5 0.1 1.3 1 0 0 1 1 1 1 ML-like domain MFS_1 PF07690.11 GAP86894.1 - 1.3e-20 73.4 57.4 1.6e-20 73.1 39.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Inhibitor_I9 PF05922.11 GAP86895.1 - 7.4e-12 45.6 0.1 1.4e-11 44.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_S8 PF00082.17 GAP86895.1 - 1e-05 24.8 3.0 1.4e-05 24.4 1.2 1.6 1 1 0 2 2 2 1 Subtilase family Evr1_Alr PF04777.8 GAP86897.1 - 1e-22 79.8 0.1 1.5e-22 79.2 0.1 1.3 1 1 0 1 1 1 1 Erv1 / Alr family Med27 PF11571.3 GAP86897.1 - 0.075 13.1 0.1 0.098 12.8 0.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 27 Proteasome PF00227.21 GAP86898.1 - 9.6e-47 158.7 0.1 1.1e-46 158.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Cyclin PF08613.6 GAP86899.1 - 1.8e-38 132.2 5.5 5.1e-23 82.1 0.1 2.8 3 0 0 3 3 3 2 Cyclin FMO-like PF00743.14 GAP86900.1 - 4.6e-20 71.3 0.0 5.4e-17 61.1 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 GAP86900.1 - 3.4e-19 69.7 0.0 6.2e-18 65.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAP86900.1 - 6e-10 39.3 0.0 1.7e-09 37.8 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP86900.1 - 1.1e-09 38.1 0.0 1.6e-08 34.4 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 GAP86900.1 - 1.5e-09 37.8 0.0 5.1e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 GAP86900.1 - 2.7e-06 26.5 0.0 0.045 12.6 0.0 2.5 1 1 0 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 GAP86900.1 - 5.1e-06 25.6 0.1 0.00034 19.6 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 GAP86900.1 - 4.7e-05 22.0 0.0 0.02 13.3 0.0 2.5 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox PF00070.22 GAP86900.1 - 0.00074 19.8 0.1 5.5 7.4 0.1 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAP86900.1 - 0.0051 15.9 0.2 0.011 14.8 0.0 1.5 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 GAP86900.1 - 0.0067 15.5 0.1 0.066 12.2 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain DUF3936 PF13072.1 GAP86900.1 - 0.066 12.6 0.2 0.15 11.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3936) Lycopene_cycl PF05834.7 GAP86900.1 - 0.15 10.9 0.0 0.27 10.1 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein TFR_dimer PF04253.10 GAP86901.1 - 1e-16 60.6 0.0 1.6e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 GAP86901.1 - 1.5e-15 57.4 0.0 2.8e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 GAP86901.1 - 9.1e-05 22.0 0.1 0.00034 20.2 0.1 2.0 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 GAP86901.1 - 0.0068 15.9 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Methyltransf_12 PF08242.7 GAP86902.1 - 7.2e-09 36.0 0.0 1.4e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP86902.1 - 2e-08 34.6 0.0 3.8e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP86902.1 - 4.6e-08 33.6 0.0 9.6e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP86902.1 - 1.4e-07 31.7 0.0 3.4e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP86902.1 - 4.4e-06 26.7 0.8 1.9e-05 24.6 0.5 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP86902.1 - 5.7e-06 26.0 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP86902.1 - 1.3e-05 24.9 0.0 1.9e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAP86902.1 - 0.041 13.2 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_PK PF05891.7 GAP86902.1 - 0.057 12.7 0.0 0.28 10.4 0.0 1.9 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase OTT_1508_deam PF14441.1 GAP86903.1 - 4e-06 26.6 1.6 5.7e-06 26.1 1.1 1.3 1 1 0 1 1 1 1 OTT_1508-like deaminase GH-E PF14410.1 GAP86903.1 - 0.05 13.7 0.7 0.14 12.3 0.5 1.7 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues dCMP_cyt_deam_1 PF00383.17 GAP86903.1 - 0.068 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region Exonuc_VII_L PF02601.10 GAP86904.1 - 8.2 5.5 18.3 1.1 8.3 7.8 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit HET PF06985.6 GAP86905.1 - 2.5e-30 105.4 0.1 4.4e-30 104.6 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 GAP86906.1 - 1.7e-28 99.4 0.1 3.8e-28 98.3 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2383 PF09537.5 GAP86907.1 - 0.34 11.1 5.4 2.2 8.5 0.1 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2383) Ribosomal_L12 PF00542.14 GAP86907.1 - 0.42 10.6 7.2 0.13 12.2 0.3 3.2 3 0 0 3 3 3 0 Ribosomal protein L7/L12 C-terminal domain RNase_H PF00075.19 GAP86908.1 - 3.6e-11 43.5 0.0 7.6e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 RNase H zf-MYND PF01753.13 GAP86908.1 - 1.7e-08 34.1 9.9 3.6e-08 33.1 6.9 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 GAP86908.1 - 0.095 12.5 7.9 0.096 12.5 3.9 2.1 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 HET PF06985.6 GAP86909.1 - 4.8e-23 81.8 0.0 1e-22 80.7 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) APH PF01636.18 GAP86910.1 - 2.4e-09 37.2 0.1 1.6e-08 34.5 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAP86910.1 - 0.00041 19.9 0.0 0.00087 18.9 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 GAP86910.1 - 0.0042 16.1 0.0 0.0094 14.9 0.0 1.5 1 0 0 1 1 1 1 Fructosamine kinase DUF1679 PF07914.6 GAP86910.1 - 0.013 14.2 0.0 0.019 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Pkinase PF00069.20 GAP86911.1 - 8.8e-24 84.0 0.0 1.1e-23 83.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP86911.1 - 2e-05 23.8 0.0 2e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAP86911.1 - 0.00014 21.6 0.1 0.019 14.6 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 GAP86911.1 - 0.093 11.5 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Methyltransf_12 PF08242.7 GAP86912.1 - 0.12 12.8 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PT PF04886.7 GAP86913.1 - 0.00025 20.3 21.5 0.0082 15.4 8.3 2.8 2 0 0 2 2 2 2 PT repeat Glyco_trans_2_3 PF13632.1 GAP86913.1 - 0.0025 17.5 0.6 0.0074 16.0 0.1 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 MFS_1 PF07690.11 GAP86914.1 - 3.9e-35 121.1 49.3 9.3e-34 116.6 33.8 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP86914.1 - 3.3e-13 49.0 15.2 3.3e-13 49.0 10.6 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 GAP86914.1 - 5.9e-13 47.8 21.0 8.4e-13 47.3 14.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.3 GAP86914.1 - 0.044 12.2 28.6 0.0071 14.8 8.1 2.5 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like p450 PF00067.17 GAP86915.1 - 1.8e-60 204.7 0.0 2.2e-60 204.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Metallophos PF00149.23 GAP86918.1 - 9.5e-37 126.3 0.6 1.4e-29 102.8 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase BDV_P10 PF06515.6 GAP86919.1 - 1.6 8.6 7.8 0.14 11.9 1.7 1.9 2 0 0 2 2 2 0 Borna disease virus P10 protein GATA PF00320.22 GAP86920.1 - 1.4e-14 53.1 2.5 2.5e-14 52.2 1.8 1.4 1 0 0 1 1 1 1 GATA zinc finger Fib_alpha PF08702.5 GAP86920.1 - 0.021 14.9 6.7 0.039 14.0 4.7 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3287 PF11690.3 GAP86920.1 - 0.03 14.3 6.1 0.082 12.9 4.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) DUF2802 PF10975.3 GAP86920.1 - 0.11 12.2 6.9 0.19 11.4 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) TF_Zn_Ribbon PF08271.7 GAP86920.1 - 0.15 11.4 0.4 0.26 10.6 0.3 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding APG6 PF04111.7 GAP86920.1 - 0.22 10.5 14.3 0.34 9.8 9.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 GAP86920.1 - 0.25 9.7 8.2 0.36 9.1 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4613 PF15390.1 GAP86920.1 - 0.48 8.5 8.9 0.7 7.9 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) CENP-F_leu_zip PF10473.4 GAP86920.1 - 0.49 10.2 18.4 3.2 7.6 0.7 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bap31 PF05529.7 GAP86920.1 - 0.64 9.4 6.5 1.4 8.3 4.5 1.5 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Fungal_trans_2 PF11951.3 GAP86920.1 - 0.77 8.2 4.4 1.2 7.6 3.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Occludin_ELL PF07303.8 GAP86920.1 - 1.8 9.3 10.9 0.14 12.8 3.3 2.2 3 0 0 3 3 2 0 Occludin homology domain HAUS6_N PF14661.1 GAP86920.1 - 1.8 7.8 10.1 4.2 6.6 7.0 1.7 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Fzo_mitofusin PF04799.8 GAP86920.1 - 2.6 7.4 5.5 2.2 7.6 2.8 1.5 1 1 0 1 1 1 0 fzo-like conserved region OPA3 PF07047.7 GAP86920.1 - 2.9 7.6 7.4 6.1 6.6 5.1 1.5 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) Fmp27_WPPW PF10359.4 GAP86920.1 - 3 6.1 11.9 4.6 5.5 8.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Mnd1 PF03962.10 GAP86920.1 - 3.6 7.1 11.9 7.3 6.2 8.2 1.5 1 0 0 1 1 1 0 Mnd1 family V_ATPase_I PF01496.14 GAP86920.1 - 6.6 4.4 7.7 9 3.9 5.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.1 GAP86920.1 - 7.3 6.8 9.0 12 6.1 6.2 1.3 1 0 0 1 1 1 0 AAA domain Microtub_assoc PF07989.6 GAP86920.1 - 8 6.3 12.5 3.8 7.4 0.3 3.0 3 0 0 3 3 3 0 Microtubule associated DUF383 PF04063.9 GAP86922.1 - 1.5e-61 207.2 0.3 3.4e-61 206.1 0.0 1.7 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 GAP86922.1 - 3e-21 74.7 1.1 3e-21 74.7 0.8 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF384) Sugar_tr PF00083.19 GAP86925.1 - 1e-47 162.7 17.7 1.3e-47 162.4 12.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP86925.1 - 4.2e-16 58.6 27.2 4.2e-16 58.6 18.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FMN_dh PF01070.13 GAP86926.1 - 1.3e-119 399.2 0.1 1.6e-119 398.9 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 GAP86926.1 - 5.2e-24 83.8 0.0 1.1e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 GAP86926.1 - 9.8e-07 28.0 0.1 1.7e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 GAP86926.1 - 0.0022 17.1 0.4 0.0037 16.4 0.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 GAP86926.1 - 0.003 16.4 0.9 0.0052 15.7 0.2 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 GAP86926.1 - 0.015 14.5 0.6 0.56 9.4 0.0 2.3 1 1 0 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.9 GAP86926.1 - 0.097 11.7 0.2 4 6.4 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Ras PF00071.17 GAP86927.1 - 6.2e-39 132.9 0.0 8.5e-37 126.0 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 GAP86927.1 - 6.8e-18 65.2 0.0 9.4e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAP86927.1 - 1.2e-09 37.6 0.0 2e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAP86927.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.5 GAP86927.1 - 0.017 14.3 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 GAP86927.1 - 0.035 13.2 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Menin PF05053.8 GAP86927.1 - 0.048 11.8 7.1 0.073 11.2 4.9 1.2 1 0 0 1 1 1 0 Menin AAA_33 PF13671.1 GAP86927.1 - 0.081 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain GRP PF07172.6 GAP86927.1 - 5.5 7.5 13.8 2 8.9 4.0 2.3 2 0 0 2 2 2 0 Glycine rich protein family AAA PF00004.24 GAP86928.1 - 9.2e-51 171.4 0.0 1.2e-40 138.7 0.0 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAP86928.1 - 2.2e-07 30.7 0.1 0.00023 20.9 0.0 3.3 3 2 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 GAP86928.1 - 5.1e-07 29.2 0.8 0.21 10.9 0.0 4.0 2 2 2 4 4 4 2 AAA domain AAA_14 PF13173.1 GAP86928.1 - 2.3e-06 27.5 0.0 0.029 14.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 GAP86928.1 - 2.7e-05 24.1 0.1 0.023 14.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAP86928.1 - 4.1e-05 23.7 1.5 0.69 10.0 0.0 4.3 3 2 1 5 5 4 1 AAA domain AAA_16 PF13191.1 GAP86928.1 - 6.6e-05 22.9 0.0 0.27 11.2 0.0 3.8 2 2 0 3 3 3 1 AAA ATPase domain Arch_ATPase PF01637.13 GAP86928.1 - 0.0002 21.1 0.0 0.19 11.3 0.0 3.3 2 2 1 3 3 3 1 Archaeal ATPase RuvB_N PF05496.7 GAP86928.1 - 0.00042 19.4 0.0 0.0086 15.1 0.0 2.7 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 GAP86928.1 - 0.00055 19.6 0.8 0.041 13.5 0.0 2.7 2 1 0 2 2 2 1 NACHT domain CDC48_N PF02359.13 GAP86928.1 - 0.00077 19.3 0.0 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_19 PF13245.1 GAP86928.1 - 0.00096 18.8 0.7 0.081 12.6 0.0 3.0 3 0 0 3 3 2 1 Part of AAA domain AAA_17 PF13207.1 GAP86928.1 - 0.0015 19.3 0.1 5.2 7.9 0.0 3.2 3 1 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 GAP86928.1 - 0.0047 17.0 0.0 2 8.6 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 GAP86928.1 - 0.0056 15.8 0.2 0.3 10.2 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 GAP86928.1 - 0.0092 15.8 0.0 1.7 8.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 GAP86928.1 - 0.014 14.0 0.1 0.036 12.7 0.0 1.6 2 0 0 2 2 2 0 TIP49 C-terminus KaiC PF06745.8 GAP86928.1 - 0.019 14.1 1.2 2.9 6.9 0.4 3.1 2 1 0 2 2 2 0 KaiC IstB_IS21 PF01695.12 GAP86928.1 - 0.035 13.5 0.0 0.5 9.7 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_2 PF07724.9 GAP86928.1 - 0.046 13.6 0.0 1.3 8.9 0.0 2.7 2 2 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_23 PF13476.1 GAP86928.1 - 0.062 13.6 0.0 0.17 12.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.7 GAP86928.1 - 0.12 11.4 0.0 20 4.2 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin DAP3 PF10236.4 GAP86928.1 - 0.14 11.0 0.1 1.3 7.9 0.0 2.3 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_3 PF07726.6 GAP86928.1 - 0.14 11.7 0.0 3.9 7.0 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 GAP86928.1 - 0.18 10.4 0.0 0.34 9.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein TAF4 PF05236.9 GAP86929.1 - 0.5 9.5 5.7 0.89 8.7 4.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Ras PF00071.17 GAP86930.1 - 1.1e-64 216.7 0.0 1.2e-64 216.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAP86930.1 - 2.4e-19 70.0 0.0 3.3e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAP86930.1 - 2.5e-13 49.6 0.0 3e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAP86930.1 - 2.5e-06 27.0 0.1 4.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAP86930.1 - 9e-06 24.9 0.0 1.1e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAP86930.1 - 0.0035 17.2 0.0 0.0053 16.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 GAP86930.1 - 0.0089 15.2 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.24 GAP86930.1 - 0.02 15.1 0.0 6 7.0 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 GAP86930.1 - 0.046 13.0 0.0 0.2 10.9 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B G-alpha PF00503.15 GAP86930.1 - 0.054 12.1 0.4 6.7 5.2 0.0 2.7 1 1 1 2 2 2 0 G-protein alpha subunit AAA_29 PF13555.1 GAP86930.1 - 0.1 12.1 0.0 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 GAP86930.1 - 0.12 12.4 0.0 0.28 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain Proteasom_PSMB PF10508.4 GAP86931.1 - 0.094 10.9 0.0 4.6 5.3 0.0 2.0 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit Zn_clus PF00172.13 GAP86932.1 - 1.8e-05 24.5 13.1 4e-05 23.4 9.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sigma70_r3 PF04539.11 GAP86932.1 - 0.16 11.8 0.4 0.34 10.8 0.3 1.5 1 0 0 1 1 1 0 Sigma-70 region 3 Sec7 PF01369.15 GAP86933.1 - 7e-65 218.2 0.1 4.2e-64 215.7 0.0 2.4 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.2 GAP86933.1 - 8.4e-51 171.7 1.4 8.4e-51 171.7 1.0 2.7 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 GAP86933.1 - 1.4e-31 107.8 4.7 7e-30 102.3 0.0 4.5 3 1 1 4 4 4 1 Domain of unknown function (DUF1981) Cnd1 PF12717.2 GAP86933.1 - 0.00028 20.8 2.5 0.12 12.2 0.0 3.6 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 2-oxoacid_dh PF00198.18 GAP86934.1 - 3.4e-79 265.3 0.2 4.5e-79 264.9 0.2 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 GAP86934.1 - 7.4e-19 67.1 0.9 1.7e-18 66.0 0.6 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 GAP86934.1 - 9.3e-13 47.5 0.9 3.4e-12 45.7 0.2 2.3 2 0 0 2 2 2 1 e3 binding domain DUF3614 PF12267.3 GAP86934.1 - 0.005 17.1 0.8 0.011 16.0 0.2 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3614) DUF2263 PF10021.4 GAP86935.1 - 8.2e-16 58.3 0.0 2.1e-15 57.0 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Fungal_trans PF04082.13 GAP86936.1 - 9.4e-11 41.0 0.0 2.4e-10 39.7 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP86936.1 - 1.6e-07 31.0 9.2 3.2e-07 30.1 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ferritin PF00210.19 GAP86936.1 - 0.032 13.9 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Ferritin-like domain IZUMO PF15005.1 GAP86936.1 - 2 8.4 5.6 10 6.1 2.9 2.2 2 0 0 2 2 2 0 Izumo sperm-egg fusion DIOX_N PF14226.1 GAP86937.1 - 7.2e-12 45.8 0.0 1.1e-11 45.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAP86937.1 - 2.8e-09 37.1 0.0 4.3e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Orexin PF02072.10 GAP86937.1 - 0.16 11.7 0.0 5.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Prepro-orexin Ferritin_2 PF13668.1 GAP86938.1 - 4.1e-07 30.0 0.0 6.4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain ketoacyl-synt PF00109.21 GAP86939.1 - 4.1e-65 219.7 0.0 8e-65 218.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAP86939.1 - 2.5e-53 181.4 0.0 4.1e-53 180.7 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 GAP86939.1 - 4.5e-52 176.3 0.0 1.1e-51 175.0 0.0 1.8 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 GAP86939.1 - 5.9e-39 133.6 0.1 2e-38 131.9 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 GAP86939.1 - 3.6e-38 131.3 0.0 7.4e-38 130.3 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 GAP86939.1 - 7.7e-38 128.9 0.1 3.2e-37 127.0 0.0 2.2 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 GAP86939.1 - 1.9e-17 63.0 0.0 1.6e-16 60.0 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 GAP86939.1 - 1.1e-15 57.9 0.0 3.1e-15 56.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 GAP86939.1 - 2.3e-11 44.6 0.0 1.4e-10 42.1 0.0 2.4 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 GAP86939.1 - 8.5e-11 41.6 0.0 2.1e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP86939.1 - 1.5e-10 41.0 0.0 3.9e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP86939.1 - 1e-09 38.7 0.0 2.9e-09 37.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP86939.1 - 1.6e-08 35.1 0.0 6.3e-08 33.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 GAP86939.1 - 1.4e-07 31.6 0.0 4.7e-07 29.9 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 GAP86939.1 - 1e-06 28.0 0.0 2.4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 GAP86939.1 - 0.02 13.9 0.3 0.05 12.5 0.2 1.6 1 0 0 1 1 1 0 Thiolase, N-terminal domain ACP_syn_III PF08545.5 GAP86939.1 - 0.022 14.4 0.6 0.059 13.0 0.4 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NAS PF03059.11 GAP86939.1 - 0.046 12.8 0.0 0.089 11.9 0.0 1.4 1 0 0 1 1 1 0 Nicotianamine synthase protein Methyltransf_28 PF02636.12 GAP86939.1 - 0.092 12.1 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.4 GAP86939.1 - 0.11 11.8 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase FSH1 PF03959.8 GAP86940.1 - 1.7e-26 92.9 0.0 5.8e-26 91.2 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 GAP86940.1 - 0.00016 21.6 0.6 0.0028 17.5 0.1 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP86940.1 - 0.077 12.7 0.1 0.12 12.1 0.1 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family p450 PF00067.17 GAP86942.1 - 4.6e-66 223.2 0.0 6e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tautomerase_2 PF14552.1 GAP86942.1 - 0.036 14.0 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 Tautomerase enzyme Ank PF00023.25 GAP86943.1 - 1.1e-07 31.2 0.1 2.8e-05 23.6 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 GAP86943.1 - 1.3e-07 31.8 0.1 1.3e-06 28.6 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAP86943.1 - 5e-06 26.2 0.5 0.0014 18.6 0.1 3.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 GAP86943.1 - 5.2e-05 23.6 0.1 0.00048 20.5 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP86943.1 - 0.0025 18.0 0.0 0.021 15.0 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Aminotran_5 PF00266.14 GAP86944.1 - 3.9e-27 94.9 0.0 5.8e-26 91.1 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 GAP86944.1 - 0.00022 20.3 0.0 0.00052 19.0 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Glyco_hydro_3 PF00933.16 GAP86945.1 - 4.3e-90 301.7 0.1 6.5e-90 301.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAP86945.1 - 5.2e-45 153.7 2.6 2.2e-39 135.3 0.1 2.5 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAP86945.1 - 1.5e-25 88.8 0.0 2.9e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain TFIIA PF03153.8 GAP86946.1 - 4.4 7.0 10.5 0.32 10.8 4.0 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Rick_17kDa_Anti PF05433.10 GAP86947.1 - 3.7e-05 23.2 12.8 3.7e-05 23.2 8.9 3.5 2 1 1 3 3 3 1 Glycine zipper 2TM domain Whi5 PF08528.6 GAP86948.1 - 2.4e-06 27.0 0.0 3.9e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Whi5 like MSP1_C PF07462.6 GAP86948.1 - 4.4 5.5 4.0 7.5 4.8 2.8 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Hus1 PF04005.7 GAP86949.1 - 7.1 5.4 4.8 98 1.7 3.4 2.1 1 1 0 1 1 1 0 Hus1-like protein ZZ PF00569.12 GAP86950.1 - 5.8e-08 32.1 31.7 5.1e-05 22.7 6.0 2.4 2 0 0 2 2 2 2 Zinc finger, ZZ type HET PF06985.6 GAP86951.1 - 8.5e-30 103.7 0.2 1.4e-29 103.0 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.20 GAP86952.1 - 1.3e-15 57.7 0.3 2.2e-15 56.9 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP86952.1 - 5.4e-08 32.7 0.1 8.8e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAP86952.1 - 0.0057 16.1 0.0 0.015 14.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 GAP86952.1 - 0.041 13.6 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAP86952.1 - 0.049 13.6 0.4 0.084 12.8 0.2 1.3 1 0 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 GAP86952.1 - 0.052 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_4 PF07993.7 GAP86953.1 - 2.6e-32 111.7 0.0 3.8e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 GAP86953.1 - 1.8e-25 89.2 0.0 3.6e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 GAP86953.1 - 1.7e-10 40.7 0.0 2.9e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 GAP86953.1 - 0.00022 20.2 0.5 0.0067 15.3 0.1 2.5 2 1 0 2 2 2 1 RmlD substrate binding domain PP-binding PF00550.20 GAP86953.1 - 0.0011 19.1 0.0 0.0027 17.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 GAP86953.1 - 0.0047 16.8 0.0 0.012 15.4 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase DUF3356 PF11836.3 GAP86953.1 - 0.045 13.5 0.1 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3356) GYF PF02213.11 GAP86954.1 - 5.3e-19 67.5 0.1 1.2e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 GYF domain TPR_11 PF13414.1 GAP86955.1 - 1.4e-14 53.5 1.8 2.5e-09 36.6 0.4 4.2 3 1 1 4 4 4 2 TPR repeat TPR_2 PF07719.12 GAP86955.1 - 6.1e-11 41.3 5.5 5.7e-05 22.7 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAP86955.1 - 9.7e-11 40.8 2.1 0.00033 20.1 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAP86955.1 - 7e-10 39.3 6.4 1e-08 35.6 0.9 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAP86955.1 - 3.8e-09 36.3 2.4 0.00073 19.4 0.0 4.1 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAP86955.1 - 1.8e-08 33.5 0.2 0.0012 18.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAP86955.1 - 2.1e-07 30.2 0.5 0.0038 16.9 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAP86955.1 - 9.6e-06 25.7 14.3 0.0012 19.3 0.1 5.9 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAP86955.1 - 0.00021 21.0 0.4 0.0021 17.8 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAP86955.1 - 0.00025 21.3 2.3 5.7 7.6 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAP86955.1 - 0.00095 19.4 2.4 2.3 8.5 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAP86955.1 - 0.072 13.3 0.1 39 4.8 0.0 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 GAP86955.1 - 0.085 12.1 0.0 0.23 10.7 0.0 1.8 1 0 0 1 1 1 0 SHNi-TPR NAD_binding_7 PF13241.1 GAP86957.1 - 2.6e-27 95.0 0.0 3.6e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 GAP86957.1 - 1.1e-26 91.9 0.0 1.6e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 GAP86957.1 - 5.5e-14 50.8 0.0 9.9e-14 50.0 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central FYVE PF01363.16 GAP86958.1 - 6.1e-24 83.7 20.7 7.7e-17 60.9 4.0 3.1 3 0 0 3 3 3 2 FYVE zinc finger zf-AN1 PF01428.11 GAP86958.1 - 0.00015 21.5 2.5 0.00015 21.5 1.7 3.3 4 0 0 4 4 4 1 AN1-like Zinc finger zf-Di19 PF05605.7 GAP86958.1 - 0.00033 20.7 7.0 0.0091 16.1 0.0 2.8 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Rbsn PF11464.3 GAP86958.1 - 0.0013 18.2 3.5 0.0018 17.7 0.1 2.8 3 0 0 3 3 3 1 Rabenosyn Rab binding domain Seryl_tRNA_N PF02403.17 GAP86958.1 - 0.0041 17.1 0.4 0.0041 17.1 0.3 2.4 3 0 0 3 3 3 1 Seryl-tRNA synthetase N-terminal domain Siva PF05458.7 GAP86958.1 - 0.075 12.5 0.0 0.075 12.5 0.0 3.0 3 0 0 3 3 3 0 Cd27 binding protein (Siva) zf-C2H2_2 PF12756.2 GAP86958.1 - 1.3 9.2 0.0 1.3 9.2 0.0 2.9 3 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) C6_DPF PF10170.4 GAP86958.1 - 1.4 8.9 5.4 0.43 10.6 0.2 2.7 3 0 0 3 3 3 0 Cysteine-rich domain GFA PF04828.9 GAP86958.1 - 7.1 6.6 10.4 0.47 10.4 1.5 3.2 3 1 1 4 4 4 0 Glutathione-dependent formaldehyde-activating enzyme DUF605 PF04652.11 GAP86959.1 - 1.7 7.9 5.9 2.2 7.5 4.1 1.1 1 0 0 1 1 1 0 Vta1 like Nop14 PF04147.7 GAP86959.1 - 3 5.6 4.8 4.2 5.1 3.4 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-L PF13092.1 GAP86960.1 - 6.5e-43 146.3 0.0 3.8e-41 140.5 0.0 2.2 2 0 0 2 2 2 2 Kinetochore complex Sim4 subunit Fta1 Ank_2 PF12796.2 GAP86961.1 - 5.8e-15 55.4 0.1 1.2e-06 28.7 0.1 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAP86961.1 - 4.6e-13 49.2 0.2 1.9e-07 31.3 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 GAP86961.1 - 2.5e-11 42.7 2.2 0.00098 18.8 0.3 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 GAP86961.1 - 3.4e-09 36.6 0.7 0.0025 18.0 0.4 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP86961.1 - 7.2e-09 35.0 0.1 0.13 12.5 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 GAP86961.1 - 9.3e-06 25.2 0.2 3.4e-05 23.4 0.1 1.9 1 1 0 1 1 1 1 KilA-N domain DUF3584 PF12128.3 GAP86961.1 - 0.003 14.9 3.2 0.0047 14.3 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Med2 PF11214.3 GAP86961.1 - 0.096 12.7 2.3 0.22 11.5 1.6 1.6 1 0 0 1 1 1 0 Mediator complex subunit 2 Fez1 PF06818.10 GAP86961.1 - 0.33 10.9 6.2 0.66 9.9 4.3 1.4 1 0 0 1 1 1 0 Fez1 DUF4407 PF14362.1 GAP86961.1 - 0.41 9.5 4.1 0.66 8.8 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BLOC1_2 PF10046.4 GAP86961.1 - 1.4 9.0 6.3 0.36 10.9 2.1 1.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Complex1_LYR PF05347.10 GAP86962.1 - 4.3e-07 29.6 1.3 9.1e-07 28.5 0.9 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAP86962.1 - 3.9e-06 26.9 0.7 7.9e-06 25.9 0.5 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Acetyltransf_1 PF00583.19 GAP86963.1 - 8.6e-14 51.3 0.0 1.3e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAP86963.1 - 3.9e-07 30.1 0.0 5.9e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAP86963.1 - 4.8e-07 29.4 0.0 8.4e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 GAP86963.1 - 5.5e-05 23.2 0.0 8e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAP86963.1 - 0.0054 16.9 0.0 0.007 16.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAP86963.1 - 0.021 14.8 0.0 0.048 13.6 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 GAP86963.1 - 0.1 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Potassium_chann PF11404.3 GAP86965.1 - 0.16 11.7 0.2 0.35 10.7 0.2 1.5 1 0 0 1 1 1 0 Potassium voltage-gated channel MFS_1 PF07690.11 GAP86967.1 - 2.1e-35 122.0 25.1 2.1e-35 122.0 17.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 GAP86967.1 - 0.037 13.5 1.7 0.12 11.8 1.2 1.8 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 DUF2721 PF11026.3 GAP86967.1 - 6.9 6.3 8.8 17 5.0 0.0 3.4 4 1 0 4 4 4 0 Protein of unknown function (DUF2721) NAD_binding_10 PF13460.1 GAP86968.1 - 1.4e-05 25.2 0.1 1.8e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAP86968.1 - 0.0042 16.0 0.1 0.1 11.5 0.0 2.3 1 1 1 3 3 3 1 Male sterility protein 3Beta_HSD PF01073.14 GAP86968.1 - 0.041 12.5 0.0 0.054 12.2 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAP86968.1 - 0.085 12.2 0.0 0.15 11.4 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 GAP86968.1 - 0.085 12.7 0.1 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 GAP86968.1 - 0.13 12.1 0.2 0.93 9.3 0.0 2.1 2 1 0 2 2 2 0 short chain dehydrogenase Zn_clus PF00172.13 GAP86969.1 - 0.0034 17.2 10.3 0.0062 16.4 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 GAP86970.1 - 1.8e-32 112.4 29.4 2.4e-32 112.0 20.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 GAP86970.1 - 0.0032 17.2 3.3 0.0078 15.9 0.5 2.8 3 0 0 3 3 3 1 MFS_1 like family Mito_fiss_reg PF05308.6 GAP86971.1 - 0.75 9.1 4.4 1.1 8.5 3.0 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CoA_trans PF01144.18 GAP86972.1 - 1.6e-59 200.7 0.8 1.5e-49 168.1 0.1 2.2 2 0 0 2 2 2 2 Coenzyme A transferase UDPG_MGDP_dh_N PF03721.9 GAP86973.1 - 2.1e-40 138.0 0.0 2.5e-30 105.2 0.0 2.4 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 GAP86973.1 - 1.4e-28 98.8 0.0 5.3e-28 97.0 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 GAP86973.1 - 1.3e-19 70.3 0.0 5.6e-15 55.4 0.0 3.3 4 0 0 4 4 4 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain HET PF06985.6 GAP86975.1 - 3.4e-30 105.0 0.0 6.5e-30 104.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Lambda_tail_I PF06805.7 GAP86975.1 - 0.14 12.0 0.0 0.36 10.6 0.0 1.7 1 1 0 1 1 1 0 Bacteriophage lambda tail assembly protein I RTA1 PF04479.8 GAP86976.1 - 1.5e-36 126.0 8.6 1.5e-36 126.0 5.9 1.6 2 0 0 2 2 2 1 RTA1 like protein DUF4131 PF13567.1 GAP86976.1 - 1.6 8.0 9.4 4 6.8 0.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Condensation PF00668.15 GAP86978.1 - 1.6e-43 148.6 0.0 1.4e-29 102.9 0.0 3.8 3 1 1 4 4 4 3 Condensation domain PP-binding PF00550.20 GAP86978.1 - 1.7e-14 53.8 0.0 4.6e-14 52.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding PF00501.23 GAP86978.1 - 0.00087 17.7 0.0 0.0016 16.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.23 GAP86979.1 - 1.6e-83 280.4 0.0 2.2e-83 279.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 GAP86979.1 - 1.6e-10 41.0 0.4 6.8e-10 39.0 0.1 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Myb_DNA-bind_3 PF12776.2 GAP86980.1 - 4.8e-17 62.3 0.4 7.8e-17 61.7 0.3 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF605 PF04652.11 GAP86980.1 - 0.32 10.3 19.0 0.55 9.5 13.2 1.5 1 0 0 1 1 1 0 Vta1 like BCS1_N PF08740.6 GAP86981.1 - 1e-22 80.6 0.3 1e-22 80.6 0.2 2.3 3 0 0 3 3 3 1 BCS1 N terminal AAA PF00004.24 GAP86981.1 - 4.7e-16 59.1 0.0 1.3e-15 57.7 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 GAP86981.1 - 4.5e-05 24.2 0.9 0.002 18.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 GAP86981.1 - 0.0048 16.5 0.0 0.0091 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 GAP86981.1 - 0.012 14.9 0.0 0.037 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 GAP86981.1 - 0.017 14.8 0.0 0.054 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAP86981.1 - 0.035 14.0 2.5 0.064 13.2 0.2 2.7 2 2 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 GAP86981.1 - 0.17 12.1 0.0 0.17 12.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 GAP86981.1 - 0.19 12.0 0.1 1.4 9.1 0.0 2.2 2 1 0 2 2 2 0 ABC transporter CHCH PF06747.8 GAP86983.1 - 2e-06 27.5 5.7 3.5e-06 26.7 3.9 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 GAP86983.1 - 0.11 12.5 1.9 0.22 11.6 1.3 1.4 1 0 0 1 1 1 0 GCK domain TPK_catalytic PF04263.11 GAP86984.1 - 8.8e-23 80.2 0.1 1.4e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 GAP86984.1 - 3.6e-19 68.2 0.0 5.9e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain PQQ_3 PF13570.1 GAP86984.1 - 0.023 14.9 0.3 0.07 13.4 0.2 1.8 1 0 0 1 1 1 0 PQQ-like domain V-SNARE_C PF12352.3 GAP86985.1 - 8.6e-14 51.3 0.2 1.9e-13 50.2 0.1 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 GAP86985.1 - 9.6e-05 22.0 0.0 0.00027 20.5 0.0 1.7 1 0 0 1 1 1 1 Sec20 Sigma70_r4 PF04545.11 GAP86985.1 - 0.02 14.2 0.1 0.037 13.3 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 DUF2408 PF10303.4 GAP86985.1 - 0.067 13.3 0.2 0.56 10.3 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) DivIC PF04977.10 GAP86985.1 - 0.11 11.9 4.0 8.1 6.0 0.0 2.6 2 0 0 2 2 2 0 Septum formation initiator MFS_1 PF07690.11 GAP86986.1 - 3.7e-52 177.1 22.8 3.7e-52 177.1 15.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP86986.1 - 4.4e-14 51.9 11.0 4.4e-14 51.9 7.6 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 GAP86986.1 - 5.2e-12 44.7 4.8 8e-12 44.1 3.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 GAP86986.1 - 3.7e-07 28.6 7.7 3.7e-07 28.6 5.3 2.7 3 1 0 3 3 3 1 Transmembrane secretion effector MFS_1_like PF12832.2 GAP86986.1 - 3.4e-06 26.7 0.6 0.0032 17.2 0.3 3.0 2 0 0 2 2 2 2 MFS_1 like family DUF791 PF05631.9 GAP86986.1 - 5.4e-05 22.0 1.2 5.4e-05 22.0 0.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF791) ATG22 PF11700.3 GAP86986.1 - 0.09 11.2 27.9 0.056 11.9 1.0 3.7 2 2 1 3 3 3 0 Vacuole effluxer Atg22 like OSTbeta PF15048.1 GAP86986.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Thiolase_N PF00108.18 GAP86988.1 - 1.9e-68 230.2 0.1 2.9e-68 229.7 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAP86988.1 - 7.8e-40 135.1 0.1 7.8e-40 135.1 0.1 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain Glyco_hydro_cc PF11790.3 GAP86989.1 - 1.8e-62 210.8 0.0 2.1e-62 210.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Pro_CA PF00484.14 GAP86990.1 - 9.1e-48 162.1 0.3 1.8e-47 161.1 0.0 1.6 2 0 0 2 2 2 1 Carbonic anhydrase BAF1_ABF1 PF04684.8 GAP86990.1 - 4.1 6.1 9.6 6.3 5.5 6.7 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor KorB_C PF06613.6 GAP86991.1 - 0.083 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 KorB C-terminal beta-barrel domain RAG2_PHD PF13341.1 GAP86991.1 - 0.11 12.4 0.3 0.22 11.5 0.2 1.5 1 0 0 1 1 1 0 RAG2 PHD domain AUX_IAA PF02309.11 GAP86992.1 - 0.0093 15.7 0.4 0.018 14.7 0.3 1.4 1 0 0 1 1 1 1 AUX/IAA family CTP_transf_1 PF01148.15 GAP86993.1 - 3.3e-81 272.7 26.8 4e-81 272.5 18.6 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family PEN-2 PF10251.4 GAP86993.1 - 0.87 9.8 12.9 10 6.4 0.0 3.3 2 1 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase DUF3636 PF12331.3 GAP86994.1 - 1.1e-33 115.9 0.2 7.7e-33 113.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3636) IncA PF04156.9 GAP86994.1 - 0.24 10.9 19.5 0.15 11.6 4.6 2.3 2 0 0 2 2 2 0 IncA protein NHL PF01436.16 GAP86995.1 - 0.0023 17.7 0.2 2.3 8.3 0.0 3.4 3 0 0 3 3 3 2 NHL repeat GSDH PF07995.6 GAP86995.1 - 0.028 13.5 0.0 0.06 12.4 0.0 1.7 2 0 0 2 2 2 0 Glucose / Sorbosone dehydrogenase SBBP PF06739.6 GAP86995.1 - 0.056 13.2 0.0 3.8 7.3 0.0 2.8 2 0 0 2 2 2 0 Beta-propeller repeat Lactonase PF10282.4 GAP86995.1 - 0.082 11.9 0.0 10 5.0 0.0 2.1 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller SGL PF08450.7 GAP86995.1 - 0.088 12.1 0.0 0.35 10.1 0.0 2.0 2 0 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Rb_C PF08934.5 GAP86995.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Rb C-terminal domain Sugar_tr PF00083.19 GAP86996.1 - 1.1e-77 261.5 20.9 1.4e-77 261.1 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP86996.1 - 6e-18 64.6 54.7 1.4e-16 60.1 16.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily CP_ATPgrasp_2 PF14403.1 GAP86996.1 - 0.16 10.6 0.0 0.23 10.0 0.0 1.1 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 DUF2456 PF10445.4 GAP86996.1 - 0.79 9.6 6.9 1.1 9.1 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) SET PF00856.23 GAP86997.1 - 6.5e-10 39.5 0.0 6.7e-09 36.2 0.0 2.4 3 0 0 3 3 3 1 SET domain TPR_12 PF13424.1 GAP86997.1 - 0.068 13.1 0.2 0.15 12.0 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat EGF_2 PF07974.8 GAP86998.1 - 0.00026 21.1 8.8 0.0005 20.1 6.1 1.5 1 0 0 1 1 1 1 EGF-like domain Nodulin_late PF07127.6 GAP86998.1 - 0.024 14.7 0.4 0.052 13.6 0.3 1.5 1 0 0 1 1 1 0 Late nodulin protein Sulfate_transp PF00916.15 GAP86999.1 - 8.4e-51 172.6 1.6 8.4e-51 172.6 1.1 1.7 1 1 1 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 GAP86999.1 - 8.9e-30 102.2 4.1 3.4e-29 100.3 2.9 2.1 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 GAP86999.1 - 3.8e-18 64.9 0.0 6.6e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 GAP86999.1 - 0.001 19.0 0.0 0.0029 17.6 0.0 1.8 1 1 0 1 1 1 1 STAS domain E1-E2_ATPase PF00122.15 GAP87000.1 - 3.6e-61 206.1 0.7 3.6e-61 206.1 0.5 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAP87000.1 - 1.3e-47 161.7 11.1 1.3e-47 161.7 7.7 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAP87000.1 - 5.8e-29 102.0 0.0 1.3e-28 100.9 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAP87000.1 - 1.6e-18 66.3 0.0 3.4e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 GAP87000.1 - 1e-11 44.0 0.3 6e-11 41.6 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 GAP87000.1 - 1.9e-11 44.4 0.0 4.1e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAP87000.1 - 0.0012 18.4 0.2 0.0029 17.2 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase p450 PF00067.17 GAP87001.1 - 1.1e-68 231.9 0.0 1.4e-68 231.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MaoC_dehydratas PF01575.14 GAP87002.1 - 5.9e-18 64.4 0.0 1e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 GAP87002.1 - 4.2e-05 23.3 0.1 0.00037 20.3 0.0 2.3 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase ATG_C PF09333.6 GAP87003.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.5 2 0 0 2 2 2 0 ATG C terminal domain Sugar_tr PF00083.19 GAP87005.1 - 2.1e-121 405.6 34.7 2.3e-121 405.5 24.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP87005.1 - 5.8e-25 87.7 55.4 3e-18 65.6 21.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fe-ADH_2 PF13685.1 GAP87006.1 - 0.017 14.4 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase HCV_core PF01542.13 GAP87006.1 - 0.07 13.5 0.6 0.16 12.4 0.1 1.8 2 0 0 2 2 2 0 Hepatitis C virus core protein HET PF06985.6 GAP87007.1 - 7e-35 120.2 0.0 3.8e-34 117.8 0.0 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NTP_transferase PF00483.18 GAP87008.1 - 1.1e-32 113.2 0.0 2.7e-32 112.0 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 GAP87008.1 - 5.2e-12 44.6 11.9 4.5e-09 35.4 2.8 4.4 1 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 GAP87008.1 - 1.3e-05 24.6 3.8 1.3e-05 24.6 2.6 3.2 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 GAP87008.1 - 0.028 14.5 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain DND1_DSRM PF14709.1 GAP87009.1 - 0.00025 21.2 0.0 0.00048 20.3 0.0 1.5 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 GAP87009.1 - 0.0053 17.3 0.0 0.013 16.0 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Prenyltrans PF00432.16 GAP87010.1 - 1.9e-37 126.4 21.1 5.3e-11 41.8 0.3 6.3 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 GAP87010.1 - 1.9e-20 73.3 0.0 2.9e-15 56.6 0.0 3.4 2 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 GAP87010.1 - 0.00025 21.0 0.0 0.0016 18.3 0.0 2.3 2 0 0 2 2 2 1 Prenyltransferase-like Zn_clus PF00172.13 GAP87011.1 - 0.0033 17.2 7.4 0.0067 16.3 5.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_BMRF2 PF04633.7 GAP87011.1 - 0.041 12.8 0.1 0.063 12.2 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus BMRF2 protein ubiquitin PF00240.18 GAP87012.1 - 4.8e-136 442.3 23.5 1.1e-33 114.4 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 GAP87012.1 - 2.2e-78 257.9 21.1 4.3e-19 67.9 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 GAP87012.1 - 2.6e-24 85.2 11.1 0.00015 21.9 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 GAP87012.1 - 5.2e-22 78.2 1.5 0.00071 19.3 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 GAP87012.1 - 5.2e-14 52.0 2.9 0.13 12.1 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 GAP87012.1 - 8.1e-14 51.5 2.4 0.13 12.5 0.0 4.2 1 1 3 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 GAP87012.1 - 9.7e-11 41.5 0.0 1.5 8.8 0.0 4.9 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 GAP87012.1 - 1.6e-06 27.9 5.8 4.5 7.2 0.0 4.2 4 0 0 4 4 4 4 GLUT4 regulating protein TUG Methyltrans_RNA PF04452.9 GAP87012.1 - 5.3e-06 25.7 0.5 2 7.5 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase FlgD_ig PF13860.1 GAP87012.1 - 6.8e-05 22.5 5.3 14 5.5 0.0 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain Plexin_cytopl PF08337.7 GAP87012.1 - 0.00045 18.6 13.5 2.3 6.4 0.2 5.7 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain Big_3_3 PF13750.1 GAP87012.1 - 0.0011 18.4 0.0 48 3.3 0.0 4.0 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) ACT_4 PF13291.1 GAP87012.1 - 0.0019 18.5 0.6 1e+02 3.3 0.0 4.2 4 0 0 4 4 4 0 ACT domain DUF3861 PF12977.2 GAP87012.1 - 0.0055 16.7 5.2 53 4.0 0.0 4.4 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) CTDII PF01556.13 GAP87012.1 - 0.023 14.5 14.3 7.9 6.4 0.2 4.4 1 1 2 4 4 4 0 DnaJ C terminal domain Tash_PEST PF07708.6 GAP87012.1 - 0.026 14.4 29.1 3.5 7.7 1.2 4.4 4 0 0 4 4 4 0 Tash protein PEST motif GABP-alpha PF11620.3 GAP87012.1 - 0.037 14.0 7.8 44 4.1 0.1 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain FERM_N PF09379.5 GAP87012.1 - 0.071 13.1 12.4 42 4.2 0.1 5.9 4 4 0 4 4 4 0 FERM N-terminal domain DUF3781 PF12636.2 GAP87012.1 - 0.4 10.6 7.4 1e+02 2.9 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) Myosin_N PF02736.14 GAP87012.1 - 1.8 8.2 8.3 1e+02 2.7 0.1 4.7 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain CDC48_2 PF02933.12 GAP87012.1 - 9.3 5.9 12.2 70 3.1 0.1 4.1 4 0 0 4 4 4 0 Cell division protein 48 (CDC48), domain 2 BRAP2 PF07576.7 GAP87013.1 - 3e-19 68.6 0.0 5.3e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 GAP87013.1 - 1.9e-17 63.0 9.1 1.9e-17 63.0 6.3 2.2 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 GAP87013.1 - 1.1e-09 37.9 9.0 1.1e-09 37.9 6.2 2.4 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.20 GAP87013.1 - 9.4e-05 21.9 6.7 0.00026 20.5 4.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAP87013.1 - 0.00013 21.6 7.6 0.00013 21.6 5.3 2.1 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAP87013.1 - 0.00035 20.5 8.3 0.00035 20.5 5.8 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAP87013.1 - 0.00066 19.3 3.8 0.0077 15.9 3.0 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 GAP87013.1 - 0.00069 19.2 6.7 0.00069 19.2 4.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF2031 PF09592.5 GAP87013.1 - 0.0012 18.0 2.5 0.0018 17.4 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2031) zf-rbx1 PF12678.2 GAP87013.1 - 0.0029 17.6 4.6 0.0029 17.6 3.2 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 GAP87013.1 - 0.0072 16.1 7.2 0.016 15.0 5.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 GAP87013.1 - 0.034 13.9 3.3 0.1 12.3 2.3 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Cep57_CLD_2 PF14197.1 GAP87013.1 - 0.061 13.2 19.4 1 9.3 4.7 2.6 1 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Cas_CXXC_CXXC PF09706.5 GAP87013.1 - 0.095 12.8 0.2 0.095 12.8 0.2 2.5 2 1 1 3 3 3 0 CRISPR-associated protein (Cas_CXXC_CXXC) Kinesin-relat_1 PF12711.2 GAP87013.1 - 0.48 10.8 10.8 1.5 9.2 2.3 2.4 1 1 0 2 2 2 0 Kinesin motor GAS PF13851.1 GAP87013.1 - 1.8 7.7 14.5 1.4 8.0 9.1 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 GAP87013.1 - 4.5 7.1 22.2 13 5.6 7.3 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 GAP87013.1 - 5.5 7.3 12.9 1.8 8.9 2.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DivIC PF04977.10 GAP87013.1 - 5.5 6.5 11.5 0.36 10.3 0.5 2.4 2 0 0 2 2 2 0 Septum formation initiator Seryl_tRNA_N PF02403.17 GAP87013.1 - 5.8 6.9 14.9 5.4 7.0 1.4 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Acyltransferase PF01553.16 GAP87014.1 - 1.9e-10 40.3 0.0 3.4e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase Suc_Fer-like PF06999.7 GAP87015.1 - 6.1e-35 121.3 0.0 8.2e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Pex14_N PF04695.8 GAP87016.1 - 3.4e-39 134.0 0.0 3.4e-39 134.0 0.0 3.0 2 1 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region V-SNARE_C PF12352.3 GAP87016.1 - 0.0018 18.3 0.8 0.037 14.1 0.0 2.8 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus ERM PF00769.14 GAP87016.1 - 0.0061 16.1 5.6 0.0061 16.1 3.9 1.6 2 0 0 2 2 2 1 Ezrin/radixin/moesin family zf-C4H2 PF10146.4 GAP87016.1 - 0.013 15.4 0.5 0.013 15.4 0.3 2.1 2 0 0 2 2 2 0 Zinc finger-containing protein Cytochrom_B562 PF07361.6 GAP87016.1 - 0.053 13.9 3.7 0.097 13.0 2.3 1.6 1 1 0 1 1 1 0 Cytochrome b562 FUSC PF04632.7 GAP87016.1 - 0.13 10.6 1.5 0.22 9.9 1.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1241 PF06840.6 GAP87016.1 - 0.16 11.1 6.0 0.4 9.9 4.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1241) Flagellin_N PF00669.15 GAP87016.1 - 0.27 11.0 3.5 0.38 10.5 1.5 1.9 1 1 0 1 1 1 0 Bacterial flagellin N-terminal helical region DUF3584 PF12128.3 GAP87016.1 - 0.27 8.5 9.9 0.37 8.0 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.7 GAP87016.1 - 0.33 10.7 5.0 1.5 8.6 0.1 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MCPsignal PF00015.16 GAP87016.1 - 0.33 10.4 5.7 0.29 10.6 1.3 2.2 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain UPF0240 PF06784.6 GAP87016.1 - 0.36 10.4 3.7 0.52 9.9 2.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0240) Atg14 PF10186.4 GAP87016.1 - 0.48 9.3 10.3 0.66 8.8 7.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1664 PF07889.7 GAP87016.1 - 0.63 9.8 6.2 2.3 8.0 3.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Nup88 PF10168.4 GAP87016.1 - 1.2 6.8 4.0 1.7 6.3 2.8 1.2 1 0 0 1 1 1 0 Nuclear pore component ADIP PF11559.3 GAP87016.1 - 1.4 8.7 10.6 2.1 8.2 6.9 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4404 PF14357.1 GAP87016.1 - 2 8.8 8.0 1.3 9.4 1.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Seryl_tRNA_N PF02403.17 GAP87016.1 - 2.5 8.1 12.4 21 5.1 1.5 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Kinesin-relat_1 PF12711.2 GAP87016.1 - 4.3 7.8 9.0 1.2 9.5 2.4 2.5 2 1 0 2 2 2 0 Kinesin motor DUF3713 PF12506.3 GAP87016.1 - 5.3 7.1 6.9 36 4.4 4.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3713) DUF445 PF04286.7 GAP87016.1 - 5.9 6.3 8.0 8.9 5.7 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) FlxA PF14282.1 GAP87016.1 - 9.1 6.2 9.9 3.8 7.5 1.2 2.7 1 1 1 2 2 2 0 FlxA-like protein Abhydrolase_3 PF07859.8 GAP87017.1 - 5.3e-45 153.5 0.2 9.8e-45 152.7 0.2 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP87017.1 - 9.1e-06 25.4 0.1 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 GAP87017.1 - 0.0022 16.7 0.0 0.0062 15.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Thioesterase PF00975.15 GAP87017.1 - 0.013 15.6 0.0 0.095 12.9 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain FAD_binding_4 PF01565.18 GAP87018.1 - 1.2e-14 54.0 0.1 2.2e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Actino_peptide PF14408.1 GAP87018.1 - 5.4 7.0 10.7 13 5.8 7.4 1.6 1 0 0 1 1 1 0 Ribosomally synthesized peptide in actinomycetes HMG_CoA_synt_C PF08540.5 GAP87019.1 - 6.5e-101 337.5 0.5 8.1e-101 337.2 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 GAP87019.1 - 1.7e-93 310.9 0.2 2.6e-93 310.3 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal PPC PF04151.10 GAP87019.1 - 0.038 14.9 0.1 7.9 7.5 0.1 2.8 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain BCS1_N PF08740.6 GAP87020.1 - 6.5e-53 179.1 3.2 6.5e-53 179.1 2.2 2.1 2 1 0 2 2 1 1 BCS1 N terminal AAA PF00004.24 GAP87020.1 - 4e-16 59.4 0.0 2.8e-07 30.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 GAP87020.1 - 0.0012 18.2 0.0 0.0029 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 GAP87020.1 - 0.0066 16.1 0.0 0.026 14.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAP87020.1 - 0.03 14.3 0.0 0.03 14.3 0.0 2.7 2 1 0 2 2 1 0 AAA ATPase domain AAA_19 PF13245.1 GAP87020.1 - 0.037 13.7 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 GAP87020.1 - 0.094 13.5 0.0 0.094 13.5 0.0 3.1 2 1 0 2 2 1 0 AAA domain AAA_22 PF13401.1 GAP87020.1 - 0.17 12.0 0.7 0.56 10.3 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 GAP87020.1 - 0.38 10.6 7.6 0.63 9.9 0.0 3.4 3 1 0 3 3 3 0 AAA domain Herpes_UL6 PF01763.11 GAP87020.1 - 1.4 7.0 10.9 2.4 6.2 7.6 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like ABC_tran PF00005.22 GAP87020.1 - 2.5 8.3 0.0 2.5 8.3 0.0 3.6 3 1 0 3 3 3 0 ABC transporter YpjP PF14005.1 GAP87020.1 - 5.6 6.7 11.4 12 5.6 7.9 1.5 1 0 0 1 1 1 0 YpjP-like protein Borrelia_P83 PF05262.6 GAP87020.1 - 6.3 4.9 37.2 10 4.2 25.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Macoilin PF09726.4 GAP87021.1 - 2.2 6.4 3.7 2.6 6.1 2.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Aminotran_5 PF00266.14 GAP87022.1 - 7.7e-14 51.1 0.0 1.1e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V SLA_LP_auto_ag PF05889.8 GAP87022.1 - 0.072 11.5 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) DUF4078 PF13300.1 GAP87024.1 - 1.6e-26 92.2 10.3 1.6e-26 92.2 7.1 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4078) SRP-alpha_N PF04086.8 GAP87024.1 - 4.7 6.5 15.7 0.36 10.1 7.1 1.7 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Homoserine_dh PF00742.14 GAP87025.1 - 6.9e-52 175.7 0.0 9.1e-52 175.3 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 GAP87025.1 - 7.9e-16 58.5 0.0 1.4e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain AAA_22 PF13401.1 GAP87025.1 - 0.045 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain p450 PF00067.17 GAP87026.1 - 6.3e-19 67.8 0.0 2.5e-17 62.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 AMP-binding PF00501.23 GAP87028.1 - 1.9e-78 263.6 0.0 4.9e-78 262.3 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme ketoacyl-synt PF00109.21 GAP87028.1 - 5.8e-52 176.6 1.0 2.1e-51 174.8 0.3 2.3 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 GAP87028.1 - 1.3e-50 171.5 2.8 1.8e-48 164.5 0.2 2.7 2 0 0 2 2 2 2 KR domain adh_short PF00106.20 GAP87028.1 - 4.2e-44 150.4 0.9 2.8e-39 134.7 0.0 2.8 2 0 0 2 2 2 2 short chain dehydrogenase NAD_binding_4 PF07993.7 GAP87028.1 - 8.4e-33 113.3 0.1 2.2e-32 111.9 0.0 1.8 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 GAP87028.1 - 7.7e-29 99.9 0.0 1.7e-28 98.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 GAP87028.1 - 2.4e-18 66.1 0.6 6.6e-13 48.7 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Condensation PF00668.15 GAP87028.1 - 2.4e-13 49.5 1.5 2e-12 46.5 0.5 2.2 1 1 1 2 2 2 1 Condensation domain Epimerase PF01370.16 GAP87028.1 - 9e-07 28.5 0.1 1.7e-05 24.3 0.1 2.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAP87028.1 - 4.7e-06 25.5 0.4 0.00031 19.5 0.2 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.18 GAP87028.1 - 1.6e-05 23.9 0.0 3.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain HxxPF_rpt PF13745.1 GAP87028.1 - 0.003 17.8 0.0 0.014 15.6 0.0 2.3 2 0 0 2 2 1 1 HxxPF-repeated domain NmrA PF05368.8 GAP87028.1 - 0.003 16.8 0.2 0.33 10.1 0.1 2.3 2 0 0 2 2 2 1 NmrA-like family MFS_1 PF07690.11 GAP87030.1 - 4.1e-12 45.4 39.3 2.2e-11 43.0 27.2 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily UCR_hinge PF02320.11 GAP87031.1 - 4.3e-25 87.4 8.3 8.1e-25 86.5 5.7 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein CDC45 PF02724.9 GAP87031.1 - 0.092 10.7 4.8 0.094 10.7 3.3 1.0 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 GAP87031.1 - 0.23 10.5 14.4 0.26 10.3 9.9 1.0 1 0 0 1 1 1 0 BUD22 Tom37_C PF11801.3 GAP87031.1 - 0.33 10.8 2.1 0.38 10.6 1.5 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain BSP_II PF05432.6 GAP87031.1 - 0.43 9.8 18.0 0.54 9.4 12.5 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) IFT57 PF10498.4 GAP87031.1 - 0.76 8.4 7.5 0.88 8.2 5.2 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Tim54 PF11711.3 GAP87031.1 - 0.81 8.2 9.5 0.86 8.1 6.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RRN3 PF05327.6 GAP87031.1 - 0.85 7.6 7.4 0.92 7.5 5.2 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DDRGK PF09756.4 GAP87031.1 - 1 8.7 15.5 1.2 8.4 10.8 1.1 1 0 0 1 1 1 0 DDRGK domain Adaptin_binding PF10199.4 GAP87031.1 - 1 9.6 11.9 1.3 9.3 8.3 1.1 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF2052 PF09747.4 GAP87031.1 - 1.1 9.1 13.8 1.4 8.8 9.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DDHD PF02862.12 GAP87031.1 - 2 8.1 4.9 2.6 7.8 3.4 1.2 1 0 0 1 1 1 0 DDHD domain Mitofilin PF09731.4 GAP87031.1 - 3.7 6.0 11.9 4 5.9 8.2 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MIP-T3 PF10243.4 GAP87031.1 - 7.8 4.8 18.9 9.8 4.5 13.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ycf1 PF05758.7 GAP87031.1 - 8.6 3.9 8.5 8.8 3.8 5.9 1.0 1 0 0 1 1 1 0 Ycf1 SAPS PF04499.10 GAP87031.1 - 9.1 4.7 6.6 9.8 4.6 4.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein WWbp PF10349.4 GAP87032.1 - 3.9e-13 50.2 0.2 7.5e-13 49.3 0.2 1.4 1 0 0 1 1 1 1 WW-domain ligand protein HSCB_C PF07743.8 GAP87032.1 - 0.048 14.1 0.2 0.082 13.3 0.2 1.4 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain Vps36_ESCRT-II PF11605.3 GAP87032.1 - 0.052 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 DUF2370 PF10176.4 GAP87032.1 - 0.25 10.6 3.3 0.35 10.1 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Drf_GBD PF06371.8 GAP87033.1 - 2e-14 53.3 0.8 2e-14 53.3 0.6 2.6 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain Methyltransf_4 PF02390.12 GAP87034.1 - 2.6e-53 180.0 0.0 3.4e-53 179.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 GAP87034.1 - 4.8e-05 23.3 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP87034.1 - 0.00055 20.4 0.0 0.001 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP87034.1 - 0.0026 18.2 0.0 0.0075 16.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 GAP87034.1 - 0.0056 15.6 0.0 0.012 14.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_25 PF13649.1 GAP87034.1 - 0.0069 16.7 0.0 0.02 15.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAP87034.1 - 0.037 13.3 0.0 0.098 12.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_31 PF13847.1 GAP87034.1 - 0.041 13.4 0.0 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 GAP87034.1 - 0.061 13.0 0.0 0.17 11.5 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 GAP87034.1 - 0.074 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF2093 PF09866.4 GAP87034.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) PXA PF02194.10 GAP87035.1 - 2.4e-51 173.9 0.2 2.4e-51 173.9 0.2 2.9 4 0 0 4 4 4 1 PXA domain Nexin_C PF08628.7 GAP87035.1 - 8e-29 100.0 0.1 8e-29 100.0 0.1 2.3 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 GAP87035.1 - 1.8e-22 79.2 0.5 2.5e-21 75.5 0.3 2.4 2 0 0 2 2 2 1 PX domain RGS PF00615.14 GAP87035.1 - 3.7e-08 33.4 0.0 1.2e-07 31.8 0.0 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain HeH PF12949.2 GAP87035.1 - 0.0034 16.8 0.1 0.01 15.3 0.1 1.8 1 0 0 1 1 1 1 HeH/LEM domain GST_C PF00043.20 GAP87036.1 - 3.7e-13 49.2 0.0 1.8e-12 47.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAP87036.1 - 1.3e-10 41.0 0.0 2.4e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAP87036.1 - 4.2e-07 30.0 0.0 1.3e-06 28.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAP87036.1 - 1e-05 25.9 0.0 1.8e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAP87036.1 - 4.4e-05 23.5 0.0 0.00013 22.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAP87036.1 - 6.2e-05 22.9 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Chorion_S16 PF05836.7 GAP87038.1 - 0.027 14.3 0.2 0.063 13.1 0.2 1.5 2 0 0 2 2 2 0 Chorion protein S16 Rad4 PF03835.10 GAP87039.1 - 6.9e-30 103.3 0.2 6.9e-30 103.3 0.1 2.0 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 GAP87039.1 - 2.1e-23 81.8 0.0 3.4e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 GAP87039.1 - 9.9e-21 73.0 0.0 2.1e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 GAP87039.1 - 4.6e-12 46.0 1.3 5.2e-11 42.6 0.0 2.9 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 GAP87039.1 - 0.0001 22.5 0.3 0.00056 20.0 0.0 2.4 2 1 0 2 2 2 1 Transglutaminase-like superfamily Adenosine_kin PF04008.9 GAP87039.1 - 0.083 12.3 0.2 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Adenosine specific kinase ABC_tran PF00005.22 GAP87040.1 - 2.6e-47 160.5 0.3 5e-26 91.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 GAP87040.1 - 1.2e-27 96.8 40.7 4.9e-16 58.6 17.0 2.5 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 GAP87040.1 - 2.1e-20 73.8 1.9 7.4e-08 32.6 0.3 4.3 3 1 0 3 3 3 3 AAA domain AAA_29 PF13555.1 GAP87040.1 - 2.5e-09 36.5 3.0 0.00029 20.2 0.3 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 GAP87040.1 - 3.6e-07 29.6 4.7 0.19 10.9 0.0 4.4 5 0 0 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 GAP87040.1 - 9.6e-07 29.3 4.1 0.0034 17.7 0.4 2.4 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 GAP87040.1 - 9.6e-05 21.6 0.5 0.35 10.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 GAP87040.1 - 0.00044 20.2 1.0 1.2 9.0 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 GAP87040.1 - 0.0025 17.2 0.3 0.57 9.5 0.0 3.1 2 1 1 3 3 3 1 AAA domain AAA_15 PF13175.1 GAP87040.1 - 0.0089 15.1 0.0 5.3 5.9 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 GAP87040.1 - 0.011 15.8 0.4 3.9 7.6 0.1 3.1 2 1 0 2 2 2 0 AAA domain FAD_binding_4 PF01565.18 GAP87040.1 - 0.013 15.0 0.0 0.034 13.6 0.0 1.7 1 0 0 1 1 1 0 FAD binding domain AAA_10 PF12846.2 GAP87040.1 - 0.027 13.9 0.7 6.6 6.0 0.3 2.5 2 0 0 2 2 2 0 AAA-like domain Zeta_toxin PF06414.7 GAP87040.1 - 0.033 13.2 0.6 1.9 7.5 0.0 2.6 3 0 0 3 3 2 0 Zeta toxin AAA_19 PF13245.1 GAP87040.1 - 0.034 13.8 1.5 21 4.9 0.0 3.8 3 0 0 3 3 3 0 Part of AAA domain SRP54 PF00448.17 GAP87040.1 - 0.036 13.5 0.9 5.3 6.4 0.3 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_33 PF13671.1 GAP87040.1 - 0.043 13.6 0.2 15 5.4 0.0 3.0 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 GAP87040.1 - 0.088 12.9 0.0 9.6 6.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.1 GAP87040.1 - 0.092 12.3 0.7 14 5.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.19 GAP87040.1 - 0.14 11.2 52.1 0.0084 15.2 13.6 4.3 3 2 0 3 3 3 0 ABC-2 type transporter G-alpha PF00503.15 GAP87040.1 - 0.19 10.3 0.0 1.8 7.1 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit AAA_28 PF13521.1 GAP87040.1 - 0.3 11.0 1.3 31 4.4 0.7 2.5 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.11 GAP87040.1 - 0.81 8.7 2.3 3.5 6.6 0.5 2.4 2 0 0 2 2 2 0 AIG1 family DUF87 PF01935.12 GAP87040.1 - 1.4 8.7 4.7 13 5.5 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_13 PF13166.1 GAP87040.1 - 2.1 6.6 0.2 31 2.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain HATPase_c PF02518.21 GAP87041.1 - 2.2e-20 72.4 0.1 4.3e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAP87041.1 - 9e-19 67.5 0.2 4.2e-18 65.4 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 GAP87041.1 - 1.1e-08 34.9 0.0 3.1e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 GAP87041.1 - 0.0001 22.4 0.0 0.031 14.3 0.0 3.6 4 0 0 4 4 4 1 GAF domain Zip PF02535.17 GAP87041.1 - 2.5 7.0 6.2 4.8 6.0 4.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PAT1 PF09770.4 GAP87041.1 - 4.7 5.3 12.2 7.3 4.6 8.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3295 PF11702.3 GAP87045.1 - 2.9e-130 435.6 37.0 5e-130 434.8 25.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 GAP87045.1 - 3.8e-12 45.5 1.7 8.7e-12 44.4 1.2 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Mu-like_Com PF10122.4 GAP87046.1 - 0.0028 16.6 1.8 0.0077 15.2 0.1 2.5 2 0 0 2 2 2 1 Mu-like prophage protein Com DUF866 PF05907.8 GAP87046.1 - 0.059 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) RWD PF05773.17 GAP87046.1 - 0.11 12.3 0.0 0.33 10.8 0.0 1.7 2 0 0 2 2 2 0 RWD domain DZR PF12773.2 GAP87046.1 - 1.4 8.7 6.4 2.7 7.8 0.4 2.5 2 0 0 2 2 2 0 Double zinc ribbon Cytochrome_C7 PF14522.1 GAP87046.1 - 7.8 6.2 6.9 2e+02 1.7 4.8 2.3 1 1 0 1 1 1 0 Cytochrome c7 Cwf_Cwc_15 PF04889.7 GAP87048.1 - 0.4 10.3 4.7 0.56 9.8 3.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Glyco_hydro_17 PF00332.13 GAP87049.1 - 0.00043 19.4 0.3 0.00078 18.5 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 RAP1 PF07218.6 GAP87049.1 - 3.5 5.5 15.0 5 5.0 10.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RCC1 PF00415.13 GAP87053.1 - 5.1e-20 71.4 5.4 0.00047 20.3 0.0 6.6 8 0 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 GAP87053.1 - 5.4e-13 48.8 0.0 5.1e-10 39.3 0.0 2.7 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.1 GAP87053.1 - 9.9e-12 45.0 0.3 4.3e-08 33.4 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) RCC1_2 PF13540.1 GAP87053.1 - 1.3e-08 34.2 0.7 1.3e-08 34.2 0.5 4.5 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.1 GAP87053.1 - 2.3e-06 27.3 0.2 0.036 14.2 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 GAP87053.1 - 0.00034 20.8 0.0 0.0012 19.1 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAP87053.1 - 0.011 16.0 0.2 0.54 10.5 0.1 3.1 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank PF00023.25 GAP87053.1 - 0.011 15.5 0.4 0.042 13.6 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat Mito_carr PF00153.22 GAP87054.1 - 1.1e-68 226.9 2.1 5.9e-25 86.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SAPS PF04499.10 GAP87055.1 - 0.34 9.5 4.3 0.61 8.6 3.0 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1510 PF07423.6 GAP87055.1 - 2.6 7.3 22.4 6.9 5.9 15.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Spore_coat_CotO PF14153.1 GAP87055.1 - 9.3 5.6 10.5 16 4.8 7.3 1.3 1 0 0 1 1 1 0 Spore coat protein CotO BUD22 PF09073.5 GAP87056.1 - 4.2e-70 237.0 40.0 3.5e-69 233.9 27.7 2.3 1 1 0 1 1 1 1 BUD22 Mito_carr PF00153.22 GAP87057.1 - 2.6e-57 190.5 4.3 4e-20 71.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein p450 PF00067.17 GAP87059.1 - 1.1e-51 175.8 0.0 1.6e-51 175.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Amidoligase_2 PF12224.3 GAP87060.1 - 3.5e-17 62.8 0.0 1.1e-12 48.1 0.0 2.1 2 0 0 2 2 2 2 Putative amidoligase enzyme Ada_Zn_binding PF02805.11 GAP87061.1 - 6.9e-26 89.6 4.6 1.2e-25 88.8 3.2 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 GAP87061.1 - 3.8e-09 36.0 0.0 8.7e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 GAP87061.1 - 7.3e-07 29.2 0.0 1.5e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain DUF1203 PF06718.6 GAP87062.1 - 1e-23 83.3 0.0 1.4e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1203) Transferase PF02458.10 GAP87063.1 - 8.8e-17 60.6 0.0 1.4e-10 40.2 0.0 2.9 2 1 0 2 2 2 2 Transferase family Pyr_redox_2 PF07992.9 GAP87064.1 - 1.4e-10 41.3 0.0 8.5e-10 38.8 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAP87064.1 - 1.2e-05 24.3 0.5 0.0038 16.1 0.1 2.9 2 1 0 3 3 3 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 GAP87064.1 - 0.00019 20.1 0.4 0.00035 19.3 0.1 1.5 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.12 GAP87064.1 - 0.00073 18.7 0.2 0.0015 17.6 0.1 1.5 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 GAP87064.1 - 0.00074 19.4 1.4 0.0022 17.9 0.1 2.5 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAP87064.1 - 0.00092 19.3 0.2 0.17 11.9 0.1 2.5 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAP87064.1 - 0.0025 17.6 0.0 0.032 14.0 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 GAP87064.1 - 0.015 14.2 0.1 0.023 13.5 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 GAP87064.1 - 0.034 13.0 0.1 0.06 12.2 0.1 1.4 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.2 GAP87064.1 - 0.044 12.8 5.0 1.2 8.1 2.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 GAP87064.1 - 0.057 12.2 1.1 0.14 10.9 0.9 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 GAP87064.1 - 0.096 12.2 0.1 0.25 10.8 0.1 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 GAP87064.1 - 0.12 10.8 0.2 0.21 10.0 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 GAP87064.1 - 0.13 11.2 0.3 0.39 9.7 0.0 1.9 3 0 0 3 3 3 0 FAD binding domain Pyr_redox PF00070.22 GAP87064.1 - 0.18 12.1 1.1 0.64 10.4 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.17 GAP87065.1 - 4.6e-41 140.8 0.0 6.5e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 eIF3_N PF09440.5 GAP87065.1 - 0.038 14.1 0.1 0.81 9.8 0.0 2.3 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain ApbA_C PF08546.6 GAP87065.1 - 0.086 12.8 0.1 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal Aminotran_4 PF01063.14 GAP87066.1 - 3.6e-11 42.9 0.0 4.6e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV 4HBT_2 PF13279.1 GAP87067.1 - 1.6e-08 35.0 0.0 2.2e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Ank_2 PF12796.2 GAP87068.1 - 7.5e-25 87.0 0.2 6.6e-14 52.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAP87068.1 - 1.8e-22 77.9 3.2 1.9e-06 27.3 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.1 GAP87068.1 - 1.7e-20 71.0 0.9 2.9e-06 26.9 0.1 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 GAP87068.1 - 9.1e-18 64.2 0.3 1.7e-06 28.3 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP87068.1 - 2.8e-17 62.3 1.9 2.4e-08 33.9 0.3 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) bZIP_1 PF00170.16 GAP87068.1 - 0.031 14.2 6.8 0.055 13.4 4.7 1.3 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.10 GAP87068.1 - 0.046 13.5 4.5 0.089 12.6 3.1 1.4 1 0 0 1 1 1 0 Basic region leucine zipper AMP-binding PF00501.23 GAP87069.1 - 1.4e-161 537.5 0.0 8.3e-85 284.6 0.0 5.6 5 1 1 6 6 6 4 AMP-binding enzyme Condensation PF00668.15 GAP87069.1 - 2.2e-105 351.8 0.1 1.1e-33 116.4 0.0 8.5 5 2 0 5 5 5 5 Condensation domain PP-binding PF00550.20 GAP87069.1 - 3e-21 75.4 0.1 1e-08 35.2 0.0 4.1 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAP87069.1 - 4.3e-07 30.7 0.0 9.3e-05 23.3 0.0 3.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AATase PF07247.7 GAP87069.1 - 0.034 12.7 0.0 2.1 6.7 0.0 2.3 2 0 0 2 2 2 0 Alcohol acetyltransferase CAT PF00302.13 GAP87069.1 - 0.045 13.3 0.0 15 5.1 0.0 3.2 4 0 0 4 4 4 0 Chloramphenicol acetyltransferase GH3 PF03321.8 GAP87069.1 - 0.17 10.4 0.7 4.8 5.5 0.0 2.9 3 0 0 3 3 3 0 GH3 auxin-responsive promoter Corona_S1 PF01600.11 GAP87069.1 - 0.53 8.5 0.1 0.9 7.7 0.1 1.2 1 0 0 1 1 1 0 Coronavirus S1 glycoprotein MFS_1 PF07690.11 GAP87070.1 - 4.6e-39 134.1 43.8 4.6e-39 134.1 30.4 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily WTF PF03303.8 GAP87070.1 - 0.36 10.1 2.7 0.26 10.6 0.3 2.0 2 0 0 2 2 2 0 WTF protein DUF2207 PF09972.4 GAP87070.1 - 1.5 7.3 6.3 2.7 6.4 0.0 3.0 3 1 0 3 3 3 0 Predicted membrane protein (DUF2207) adh_short PF00106.20 GAP87071.1 - 9.7e-16 58.1 2.4 1.3e-15 57.7 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP87071.1 - 1.6e-10 40.9 1.0 2.1e-10 40.5 0.7 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAP87071.1 - 2e-05 24.4 0.0 2.7e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.21 GAP87071.1 - 0.012 15.1 0.7 0.025 14.1 0.5 1.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 GAP87071.1 - 0.013 15.5 2.7 0.046 13.7 1.9 1.9 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 GAP87071.1 - 0.14 11.6 0.0 0.29 10.5 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAP87072.1 - 9.1e-27 93.9 6.5 1.3e-26 93.5 4.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP87072.1 - 6e-17 62.2 0.0 7.5e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP87072.1 - 3.3e-10 39.9 3.9 5.1e-10 39.3 2.7 1.2 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 GAP87072.1 - 0.00099 18.9 1.2 0.0014 18.4 0.1 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 GAP87072.1 - 0.0012 18.5 0.3 0.1 12.1 0.1 2.1 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Polysacc_synt_2 PF02719.10 GAP87072.1 - 0.0014 17.6 0.0 0.0021 17.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 GAP87072.1 - 0.0038 16.9 0.2 0.0038 16.9 0.1 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FliG_C PF01706.11 GAP87072.1 - 0.02 14.8 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 FliG C-terminal domain 2-Hacid_dh_C PF02826.14 GAP87072.1 - 0.024 13.8 0.1 0.081 12.0 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.16 GAP87072.1 - 0.08 12.3 0.3 0.24 10.7 0.1 1.7 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family FAD_binding_4 PF01565.18 GAP87073.1 - 6.9e-14 51.5 0.0 1.9e-13 50.1 0.0 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP87073.1 - 2e-06 27.6 0.4 4.3e-06 26.5 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.17 GAP87074.1 - 8.4e-60 202.6 0.0 9.9e-60 202.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 GAP87075.1 - 1.3e-54 185.4 0.0 1.7e-54 185.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 GAP87076.1 - 1.1e-21 77.4 0.1 2.1e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 GAP87076.1 - 8.3e-18 65.0 0.0 1.3e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 GAP87076.1 - 1.1e-11 44.5 0.0 2.9e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 GAP87076.1 - 0.04 12.9 0.0 0.077 11.9 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain p450 PF00067.17 GAP87077.1 - 9.5e-62 209.0 0.0 1.5e-61 208.3 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 Serglycin PF04360.7 GAP87078.1 - 0.0023 17.6 0.3 0.0029 17.3 0.2 1.2 1 0 0 1 1 1 1 Serglycin Thiolase_N PF00108.18 GAP87079.1 - 7e-77 257.9 2.6 1e-76 257.4 1.8 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAP87079.1 - 2.2e-44 149.8 0.2 5.5e-44 148.5 0.1 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 GAP87079.1 - 0.04 13.9 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal OCD_Mu_crystall PF02423.10 GAP87080.1 - 1.7e-15 56.6 0.2 2.4e-08 33.1 0.0 2.4 3 0 0 3 3 3 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 GAP87080.1 - 0.0068 16.5 0.1 0.2 11.7 0.0 2.3 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pro_CA PF00484.14 GAP87081.1 - 2.6e-45 154.1 0.1 3.2e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Ribosomal_L7Ae PF01248.21 GAP87082.1 - 1.9e-19 68.9 0.6 3.3e-19 68.1 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ATP_bind_3 PF01171.15 GAP87083.1 - 8.3e-19 67.7 0.0 1.4e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 GAP87083.1 - 0.002 18.4 0.0 0.0048 17.2 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) RecR PF02132.10 GAP87083.1 - 0.0021 17.4 0.7 0.0021 17.4 0.5 2.9 3 0 0 3 3 3 1 RecR protein tRNA_Me_trans PF03054.11 GAP87083.1 - 0.004 15.7 0.0 0.0065 15.0 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase MOZ_SAS PF01853.13 GAP87085.1 - 8.1e-80 266.5 0.1 1.3e-79 265.8 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family Peptidase_M28 PF04389.12 GAP87086.1 - 4.7e-38 130.7 0.0 6e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 ENTH PF01417.15 GAP87087.1 - 2.9e-48 162.8 0.1 5.2e-48 162.0 0.0 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 GAP87087.1 - 0.0012 17.6 0.0 0.0022 16.7 0.0 1.4 1 0 0 1 1 1 1 ANTH domain DUF4264 PF14084.1 GAP87087.1 - 0.0043 16.3 0.1 0.0077 15.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4264) UIM PF02809.15 GAP87087.1 - 0.013 15.0 1.5 0.064 12.8 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif VHS PF00790.14 GAP87087.1 - 0.077 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 VHS domain DUF1510 PF07423.6 GAP87087.1 - 9.6 5.5 13.1 0.32 10.3 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) EF-hand_1 PF00036.27 GAP87088.1 - 1.1e-14 52.5 6.2 6.3e-05 22.0 0.5 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 GAP87088.1 - 1.9e-14 52.1 5.4 7.9e-06 25.3 0.6 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.1 GAP87088.1 - 3.6e-14 52.6 0.0 1.7e-07 31.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 GAP87088.1 - 8.2e-14 50.9 2.0 2.5e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 GAP87088.1 - 4.9e-06 25.6 3.3 0.032 13.5 0.3 3.6 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.2 GAP87088.1 - 0.021 14.5 0.8 0.23 11.2 0.2 2.0 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 GAP87088.1 - 0.093 12.6 0.0 2.1 8.3 0.0 2.8 1 1 2 4 4 4 0 EF-hand domain Nup96 PF12110.3 GAP87089.1 - 2.1e-86 289.6 0.4 2.9e-86 289.1 0.3 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 GAP87089.1 - 1.1e-42 145.2 0.0 1.8e-42 144.4 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 GAP87089.1 - 1.1e-21 77.2 369.0 1e-11 45.0 32.5 10.7 5 2 6 11 11 11 6 Nucleoporin FG repeat region SIR2 PF02146.12 GAP87090.1 - 2.1e-56 190.4 0.0 3.4e-56 189.7 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 GAP87090.1 - 0.0016 18.0 0.0 0.0031 17.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 GAP87090.1 - 0.0043 16.8 0.1 0.44 10.3 0.0 2.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF2360 PF10152.4 GAP87090.1 - 0.21 11.8 2.4 54 4.0 2.9 2.4 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Med3 PF11593.3 GAP87090.1 - 0.24 10.5 8.7 0.41 9.8 6.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal E1-E2_ATPase PF00122.15 GAP87091.1 - 9.5e-53 178.5 0.8 9.5e-53 178.5 0.6 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAP87091.1 - 2.5e-41 141.1 7.7 2.5e-41 141.1 5.3 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAP87091.1 - 4.3e-29 102.4 0.0 5.8e-28 98.7 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAP87091.1 - 3.5e-19 68.5 0.0 7.1e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 GAP87091.1 - 6.5e-17 62.3 0.0 1.3e-16 61.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAP87091.1 - 2.2e-09 36.6 0.0 1e-08 34.5 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 GAP87091.1 - 5.1e-05 22.9 0.6 0.0003 20.4 0.3 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Zn_clus PF00172.13 GAP87092.1 - 8.8e-06 25.5 13.7 1.8e-05 24.5 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flavokinase PF01687.12 GAP87094.1 - 1.4e-31 108.9 0.0 3e-30 104.6 0.0 2.0 1 1 0 1 1 1 1 Riboflavin kinase PAS PF00989.19 GAP87095.1 - 0.011 15.4 0.0 0.15 11.8 0.0 2.3 2 0 0 2 2 2 0 PAS fold Zn_clus PF00172.13 GAP87095.1 - 0.012 15.5 7.9 0.012 15.5 5.5 2.0 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Cellulase PF00150.13 GAP87096.1 - 5.6e-11 42.1 0.0 5.6e-11 42.1 0.0 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) EphA2_TM PF14575.1 GAP87096.1 - 0.00038 20.7 0.4 0.0012 19.2 0.0 2.0 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Synaptobrevin PF00957.16 GAP87096.1 - 0.011 15.3 0.2 0.018 14.6 0.2 1.3 1 0 0 1 1 1 0 Synaptobrevin OppC_N PF12911.2 GAP87096.1 - 0.15 11.4 0.2 0.35 10.2 0.1 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Protocadherin PF08374.6 GAP87096.1 - 0.24 11.0 0.0 0.24 11.0 0.0 2.2 2 1 0 2 2 2 0 Protocadherin DUF1510 PF07423.6 GAP87096.1 - 0.34 10.2 0.0 0.34 10.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) ORC6 PF05460.8 GAP87096.1 - 0.69 8.9 5.1 1 8.3 3.5 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Transket_pyr PF02779.19 GAP87097.1 - 2.2e-44 151.1 0.0 3.2e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 GAP87097.1 - 1.1e-30 106.1 0.0 3.5e-30 104.4 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain F-actin_cap_A PF01267.12 GAP87098.1 - 4.2e-93 311.3 0.0 4.7e-93 311.1 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Cyt-b5 PF00173.23 GAP87099.1 - 2.8e-25 87.9 0.4 3.5e-25 87.6 0.2 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF347 PF03988.7 GAP87099.1 - 0.064 13.1 0.2 0.095 12.6 0.1 1.2 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) NACHT PF05729.7 GAP87100.1 - 9.7e-12 44.8 0.2 2.2e-10 40.4 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.1 GAP87100.1 - 0.00011 22.3 0.0 0.0012 19.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 GAP87100.1 - 0.00083 18.8 0.0 0.0021 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 GAP87100.1 - 0.0015 18.5 0.0 0.0053 16.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 GAP87100.1 - 0.002 18.9 0.0 0.012 16.4 0.0 2.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAP87100.1 - 0.0039 17.4 0.0 0.028 14.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 GAP87100.1 - 0.0066 16.8 0.5 0.052 13.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 GAP87100.1 - 0.0073 15.7 0.0 0.02 14.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 GAP87100.1 - 0.0079 16.4 0.0 0.023 14.9 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA PF00004.24 GAP87100.1 - 0.013 15.7 0.0 0.91 9.7 0.0 3.8 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 GAP87100.1 - 0.018 15.2 0.0 0.1 12.7 0.0 2.3 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.18 GAP87100.1 - 0.062 13.2 0.0 0.34 10.8 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.1 GAP87100.1 - 0.064 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 GAP87100.1 - 0.068 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 GAP87100.1 - 0.098 12.2 0.0 0.41 10.2 0.0 2.1 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 GAP87100.1 - 0.1 13.0 0.0 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_19 PF13245.1 GAP87100.1 - 0.14 11.9 0.0 3 7.6 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain TFIIE_beta PF02186.10 GAP87101.1 - 3.4e-05 23.7 0.3 7.8e-05 22.5 0.2 1.6 1 0 0 1 1 1 1 TFIIE beta subunit core domain Menin PF05053.8 GAP87101.1 - 0.1 10.7 6.3 0.15 10.2 4.4 1.3 1 0 0 1 1 1 0 Menin Secretin_N_2 PF07655.8 GAP87101.1 - 8.5 6.8 16.9 21 5.5 11.7 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain DSBA PF01323.15 GAP87102.1 - 2.3e-09 37.1 0.0 1.3e-05 24.8 0.0 2.5 2 1 0 2 2 2 2 DSBA-like thioredoxin domain zf-H2C2_2 PF13465.1 GAP87103.1 - 8.2e-21 73.2 23.9 1e-06 28.7 0.4 5.4 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 GAP87103.1 - 6.9e-20 70.1 25.9 2.7e-05 24.2 1.2 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP87103.1 - 3e-13 49.0 25.2 0.0016 18.6 0.6 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAP87103.1 - 0.00039 20.4 6.9 0.66 10.2 0.0 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding XPA_N PF01286.13 GAP87103.1 - 0.091 12.4 0.3 0.091 12.4 0.2 2.5 3 0 0 3 3 3 0 XPA protein N-terminal zf-met PF12874.2 GAP87103.1 - 0.12 12.6 10.3 3.3 8.0 0.0 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DUF2072 PF09845.4 GAP87103.1 - 0.19 11.6 0.6 0.47 10.3 0.4 1.6 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) zf-C2H2_6 PF13912.1 GAP87103.1 - 0.27 11.1 11.3 5.7 6.9 0.2 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 GAP87103.1 - 2.7 7.7 7.8 15 5.3 0.3 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.5 GAP87103.1 - 4.4 7.3 7.7 6.3 6.8 0.7 3.3 3 1 0 3 3 3 0 Zinc ribbon domain Acetyltransf_7 PF13508.1 GAP87105.1 - 3.9e-07 30.1 0.0 9e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAP87105.1 - 0.0002 21.3 0.0 0.00032 20.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAP87105.1 - 0.0014 18.7 0.0 0.0039 17.2 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain NAD_binding_4 PF07993.7 GAP87106.1 - 3.1e-30 104.9 0.0 4.6e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 GAP87106.1 - 2.4e-26 92.1 0.0 7.1e-26 90.5 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 GAP87106.1 - 2.7e-10 40.0 0.0 4.8e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 GAP87106.1 - 1.8e-05 24.8 0.3 5.3e-05 23.3 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 GAP87106.1 - 0.02 14.7 0.2 0.45 10.4 0.1 2.8 2 1 0 2 2 2 0 short chain dehydrogenase 3Beta_HSD PF01073.14 GAP87106.1 - 0.026 13.2 0.0 0.22 10.2 0.0 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family zf-RING_2 PF13639.1 GAP87107.1 - 5.3e-11 42.1 1.9 7.2e-11 41.7 1.3 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAP87107.1 - 6.8e-07 29.2 0.4 1.8e-06 27.9 0.3 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 GAP87107.1 - 6.6e-06 25.7 0.2 9e-06 25.2 0.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAP87107.1 - 8.5e-06 25.7 2.0 1.2e-05 25.2 1.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAP87107.1 - 0.00025 20.6 0.4 0.00038 20.0 0.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAP87107.1 - 0.00053 19.7 0.6 0.00092 19.0 0.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.9 GAP87107.1 - 0.0058 16.0 0.9 0.083 12.3 0.1 2.4 3 0 0 3 3 3 1 Rad50 zinc hook motif zf-Di19 PF05605.7 GAP87107.1 - 0.024 14.7 0.4 8.9 6.5 0.0 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_3 PF14369.1 GAP87107.1 - 0.031 14.2 3.2 0.14 12.1 0.1 2.5 3 0 0 3 3 3 0 zinc-finger zf-UDP PF14569.1 GAP87107.1 - 0.035 13.8 0.3 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_5 PF14634.1 GAP87107.1 - 0.041 13.6 0.6 0.089 12.5 0.4 1.6 1 1 0 1 1 1 0 zinc-RING finger domain zf-C4_Topoisom PF01396.14 GAP87107.1 - 0.088 12.3 1.7 0.27 10.7 0.2 2.1 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger FANCL_C PF11793.3 GAP87107.1 - 0.16 11.9 1.5 7.5 6.5 1.0 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 GAP87107.1 - 1.5 8.7 4.9 13 5.7 4.1 2.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 GAP87107.1 - 2 8.1 5.9 0.97 9.1 0.3 2.5 3 0 0 3 3 3 0 RING-type zinc-finger Nop14 PF04147.7 GAP87109.1 - 2.9 5.6 5.3 3.7 5.3 3.7 1.0 1 0 0 1 1 1 0 Nop14-like family Ank_2 PF12796.2 GAP87110.1 - 3.9e-10 39.9 0.0 2.4e-06 27.7 0.0 3.8 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAP87110.1 - 8.8e-10 37.8 0.0 8.4e-05 22.4 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 GAP87110.1 - 1.9e-09 36.8 0.2 5.1e-06 26.0 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 GAP87110.1 - 6.5e-08 32.8 0.2 0.0016 18.8 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP87110.1 - 1.5e-05 25.0 0.4 0.0026 17.9 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Piwi PF02171.12 GAP87111.1 - 3.8e-77 259.2 0.0 5.2e-77 258.7 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 GAP87111.1 - 1.9e-09 36.9 0.0 3.4e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 GAP87111.1 - 1.3e-07 30.8 0.0 3.3e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Phytoreo_P8 PF07124.6 GAP87111.1 - 0.049 12.2 0.0 0.078 11.6 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus outer capsid protein P8 DUF4175 PF13779.1 GAP87111.1 - 5.5 4.5 9.5 9.3 3.8 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) dCMP_cyt_deam_1 PF00383.17 GAP87112.1 - 5.7e-14 51.6 0.1 7.4e-14 51.2 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 GAP87112.1 - 0.035 13.7 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain DnaJ PF00226.26 GAP87113.1 - 9.6e-24 82.9 1.1 2.9e-23 81.3 0.8 1.9 1 0 0 1 1 1 1 DnaJ domain SIMPL PF04402.9 GAP87113.1 - 0.0077 16.1 1.3 0.019 14.8 0.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF541) PNPase PF03726.9 GAP87113.1 - 0.18 12.1 10.9 4.3 7.6 0.1 4.1 4 0 0 4 4 4 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain WD40 PF00400.27 GAP87114.1 - 1.4e-76 249.8 35.0 1.1e-13 50.5 0.1 13.3 13 0 0 13 13 13 10 WD domain, G-beta repeat NACHT PF05729.7 GAP87114.1 - 9e-18 64.4 0.0 1.8e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF1513 PF07433.6 GAP87114.1 - 2.9e-07 29.6 1.6 2.1 7.1 0.0 6.9 2 2 7 9 9 9 3 Protein of unknown function (DUF1513) AAA_16 PF13191.1 GAP87114.1 - 0.00063 19.7 0.2 0.0079 16.1 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAP87114.1 - 0.0073 16.4 0.0 0.031 14.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain Glu_cyclase_2 PF05096.7 GAP87114.1 - 0.0088 15.0 0.1 32 3.4 0.0 4.3 1 1 3 4 4 4 0 Glutamine cyclotransferase Rax2 PF12768.2 GAP87114.1 - 0.0091 15.2 0.7 44 3.1 0.0 5.1 3 1 3 6 6 6 0 Cortical protein marker for cell polarity RNA_helicase PF00910.17 GAP87114.1 - 0.026 14.6 0.0 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 RNA helicase DUF642 PF04862.7 GAP87114.1 - 0.063 12.9 3.1 13 5.4 0.0 4.4 3 1 2 6 6 6 0 Protein of unknown function (DUF642) AAA_11 PF13086.1 GAP87114.1 - 0.22 11.0 0.0 0.22 11.0 0.0 2.5 2 1 1 3 3 3 0 AAA domain Stn1 PF10451.4 GAP87115.1 - 8.8e-14 50.9 0.0 2.6e-08 33.0 0.0 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 GAP87115.1 - 4.4e-05 23.2 0.3 0.071 12.9 0.1 2.4 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain Transformer PF06495.6 GAP87115.1 - 2.5 7.9 10.3 3.9 7.3 7.1 1.2 1 0 0 1 1 1 0 Fruit fly transformer protein Glyco_hydro_81 PF03639.8 GAP87116.1 - 2.1e-199 663.9 2.0 2.6e-199 663.6 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Na_Ca_ex PF01699.19 GAP87117.1 - 1.6e-47 160.5 27.4 2.9e-24 85.2 4.7 2.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF4131 PF13567.1 GAP87117.1 - 5.5 6.3 7.0 5.7 6.3 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Glyoxalase PF00903.20 GAP87118.1 - 6.3e-41 139.3 0.1 3.4e-20 72.3 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAP87118.1 - 4.4e-30 104.4 0.5 2.1e-14 54.0 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 GAP87118.1 - 3.4e-17 62.4 0.1 6.2e-07 29.4 0.0 4.2 2 2 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 GAP87118.1 - 2.5e-06 27.5 0.0 0.0062 16.4 0.0 2.8 1 1 1 2 2 2 2 Glyoxalase-like domain 2-Hacid_dh_C PF02826.14 GAP87119.1 - 5.8e-52 175.4 0.0 9.7e-52 174.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAP87119.1 - 1.2e-35 121.8 0.1 2.4e-35 120.9 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3HCDH_N PF02737.13 GAP87119.1 - 0.13 11.8 0.1 0.13 11.8 0.1 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.11 GAP87120.1 - 1e-31 109.9 28.9 4.5e-21 74.9 11.6 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAP87120.1 - 1.1e-09 37.2 18.8 5.2e-08 31.7 2.9 3.0 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 GAP87120.1 - 0.00013 21.7 4.6 0.84 9.4 0.2 3.7 3 0 0 3 3 3 2 MFS_1 like family ATG22 PF11700.3 GAP87120.1 - 0.00065 18.2 4.8 0.00065 18.2 3.3 2.6 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like DUF4493 PF14900.1 GAP87121.1 - 0.077 12.6 3.1 0.22 11.0 0.3 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4493) CarboxypepD_reg PF13620.1 GAP87121.1 - 0.088 12.8 2.7 0.35 10.9 0.4 2.7 3 0 0 3 3 3 0 Carboxypeptidase regulatory-like domain Toxin_11 PF07473.6 GAP87122.1 - 0.0017 18.1 1.2 0.0038 17.0 0.8 1.6 1 0 0 1 1 1 1 Spasmodic peptide gm9a Kelch_1 PF01344.20 GAP87122.1 - 0.0078 15.7 0.1 0.017 14.6 0.1 1.6 1 0 0 1 1 1 1 Kelch motif SLR1-BP PF07333.7 GAP87122.1 - 0.019 15.1 3.8 0.036 14.3 2.6 1.5 1 0 0 1 1 1 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) VRP1 PF03538.9 GAP87123.1 - 0.0001 21.4 0.0 0.0002 20.5 0.0 1.4 1 0 0 1 1 1 1 Salmonella virulence plasmid 28.1kDa A protein DUF3439 PF11921.3 GAP87124.1 - 0.3 10.8 3.2 0.6 9.8 2.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 GAP87124.1 - 2.8 5.5 7.0 3.9 5.1 4.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein HSP70 PF00012.15 GAP87125.1 - 6.3e-11 40.9 0.3 2.6e-09 35.5 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 GAP87125.1 - 0.0041 16.7 0.1 0.0092 15.6 0.1 1.5 1 0 0 1 1 1 1 SAP30 zinc-finger Thaumatin PF00314.12 GAP87126.1 - 8.3e-21 74.4 2.0 1e-20 74.1 1.4 1.1 1 0 0 1 1 1 1 Thaumatin family Thaumatin PF00314.12 GAP87127.1 - 2.6e-26 92.3 0.0 3.5e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Thaumatin family Ank_2 PF12796.2 GAP87128.1 - 4.5e-10 39.7 0.0 7.8e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAP87128.1 - 2.1e-09 36.6 0.0 0.0068 16.1 0.0 3.8 3 1 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 GAP87128.1 - 1.2e-08 35.2 0.9 0.00011 22.6 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP87128.1 - 5.1e-07 29.3 0.0 0.095 12.9 0.0 3.7 3 1 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 GAP87128.1 - 0.00026 21.1 0.1 0.58 10.4 0.1 3.9 3 1 1 4 4 4 1 Ankyrin repeats (many copies) TFIIS_C PF01096.13 GAP87129.1 - 7.4e-20 70.2 2.6 7.4e-20 70.2 1.8 2.9 3 1 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 GAP87129.1 - 8.1e-08 31.8 1.8 2.1e-07 30.4 0.3 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit DUF2387 PF09526.5 GAP87129.1 - 0.0002 21.2 4.4 0.002 18.0 0.3 2.3 1 1 1 2 2 2 1 Probable metal-binding protein (DUF2387) Elf1 PF05129.8 GAP87129.1 - 0.0023 17.5 3.0 0.037 13.7 0.1 2.3 2 1 0 2 2 2 1 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 GAP87129.1 - 0.0026 17.5 6.7 0.21 11.4 0.6 2.4 2 0 0 2 2 2 2 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.1 GAP87129.1 - 0.021 14.5 7.9 0.64 9.7 0.4 3.4 3 1 0 3 3 3 0 zinc-ribbon domain Nudix_N_2 PF14803.1 GAP87129.1 - 0.031 13.9 5.4 0.041 13.5 0.9 2.3 2 0 0 2 2 2 0 Nudix N-terminal zinc_ribbon_5 PF13719.1 GAP87129.1 - 0.048 13.2 7.9 1.2 8.7 0.5 3.3 3 1 0 3 3 3 0 zinc-ribbon domain C1_4 PF07975.7 GAP87129.1 - 0.063 13.2 4.7 2.3 8.2 0.2 2.5 3 0 0 3 3 2 0 TFIIH C1-like domain Desulfoferrod_N PF06397.7 GAP87129.1 - 0.082 12.3 1.3 0.66 9.4 0.1 2.4 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain UPF0547 PF10571.4 GAP87129.1 - 0.091 12.4 4.2 7.4 6.3 0.5 3.0 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 Glyco_hydro_49 PF03718.8 GAP87129.1 - 0.14 10.1 0.0 0.2 9.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 49 DZR PF12773.2 GAP87129.1 - 0.15 11.9 7.5 0.17 11.7 0.3 2.5 2 1 0 2 2 2 0 Double zinc ribbon Zn_ribbon_recom PF13408.1 GAP87129.1 - 0.15 12.3 4.2 0.61 10.3 0.7 2.6 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Baculo_LEF5_C PF11792.3 GAP87129.1 - 0.27 10.6 0.2 0.27 10.6 0.1 2.0 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain Ribosomal_S27e PF01667.12 GAP87129.1 - 0.39 10.2 4.2 1.5 8.4 0.2 2.8 3 0 0 3 3 3 0 Ribosomal protein S27 C1_3 PF07649.7 GAP87129.1 - 0.61 10.1 6.8 0.67 10.0 0.2 3.1 3 0 0 3 3 3 0 C1-like domain IBR PF01485.16 GAP87129.1 - 0.98 9.3 9.6 6.2 6.7 0.4 2.8 2 1 0 2 2 2 0 IBR domain Zn-ribbon_8 PF09723.5 GAP87129.1 - 1.1 9.2 7.7 11 6.0 0.6 3.2 3 0 0 3 3 3 0 Zinc ribbon domain Rubredoxin PF00301.15 GAP87129.1 - 6.2 6.7 7.1 37 4.2 0.2 3.4 3 0 0 3 3 3 0 Rubredoxin OrfB_Zn_ribbon PF07282.6 GAP87129.1 - 6.5 6.4 9.2 7.7 6.2 1.1 2.9 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf-Mss51 PF13824.1 GAP87129.1 - 8.5 6.3 7.0 6.2 6.7 0.6 2.4 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 CFEM PF05730.6 GAP87130.1 - 6.2e-11 41.9 8.9 9.1e-11 41.4 6.1 1.2 1 0 0 1 1 1 1 CFEM domain Mito_carr PF00153.22 GAP87130.1 - 0.58 9.8 0.1 0.58 9.8 0.1 2.9 4 0 0 4 4 4 0 Mitochondrial carrier protein FAD_binding_4 PF01565.18 GAP87131.1 - 4.8e-18 64.9 2.3 7.5e-18 64.3 1.6 1.3 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.9 GAP87131.1 - 0.001 18.7 0.4 0.095 12.2 0.3 2.3 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase WD40 PF00400.27 GAP87136.1 - 5.4e-16 57.7 1.6 3.5e-06 26.6 0.1 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_3 PF13570.1 GAP87136.1 - 0.00011 22.4 0.0 2.5 8.4 0.0 3.8 3 0 0 3 3 3 2 PQQ-like domain PQQ_2 PF13360.1 GAP87136.1 - 0.00095 18.6 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 PQQ-like domain Ras PF00071.17 GAP87137.1 - 8e-51 171.6 0.0 9.4e-51 171.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAP87137.1 - 2.5e-18 66.7 0.0 4.4e-18 65.9 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAP87137.1 - 3.2e-09 36.2 0.0 4.1e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAP87137.1 - 0.00015 21.2 0.2 0.0014 18.0 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAP87137.1 - 0.00028 20.8 0.0 0.00045 20.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 GAP87137.1 - 0.0023 18.0 0.1 0.023 14.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.7 GAP87137.1 - 0.007 15.5 0.0 0.0088 15.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 GAP87137.1 - 0.059 12.5 0.0 0.12 11.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 GAP87137.1 - 0.097 12.5 0.0 0.25 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 GAP87137.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.1 GAP87137.1 - 0.11 12.4 0.0 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 GAP87137.1 - 0.25 11.2 0.0 0.25 11.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain RRM_1 PF00076.17 GAP87139.1 - 2.1e-21 75.3 0.0 3.1e-12 45.9 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP87139.1 - 2.5e-12 46.5 0.0 8.1e-05 22.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP87139.1 - 0.021 14.6 0.0 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_23 PF13489.1 GAP87141.1 - 1.7e-22 79.8 0.0 5.2e-22 78.2 0.0 1.8 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP87141.1 - 2.7e-14 53.0 0.0 8.8e-14 51.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP87141.1 - 1e-13 51.8 0.0 1.1e-12 48.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP87141.1 - 3.5e-13 49.8 0.0 7.1e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP87141.1 - 4.1e-10 40.0 0.0 2e-08 34.5 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP87141.1 - 0.00017 21.8 0.0 0.00044 20.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAP87141.1 - 0.0019 17.5 0.0 0.012 15.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 GAP87141.1 - 0.0024 17.8 0.1 0.016 15.2 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAP87141.1 - 0.0027 16.7 0.0 0.059 12.4 0.0 2.4 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 GAP87141.1 - 0.0038 17.2 0.0 0.007 16.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase CheR PF01739.13 GAP87141.1 - 0.018 14.3 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain GidB PF02527.10 GAP87141.1 - 0.021 13.9 0.0 0.06 12.4 0.0 1.7 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G PrmA PF06325.8 GAP87141.1 - 0.03 13.4 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 GAP87141.1 - 0.04 13.4 0.0 0.42 10.1 0.0 2.0 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_29 PF03141.11 GAP87141.1 - 0.066 11.5 0.0 3.5 5.8 0.0 2.0 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.4 GAP87141.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Zn_clus PF00172.13 GAP87142.1 - 0.0021 17.9 9.5 0.0033 17.3 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EGF_2 PF07974.8 GAP87144.1 - 1.7 8.9 10.7 3.1 8.0 7.4 1.4 1 0 0 1 1 1 0 EGF-like domain HNH_2 PF13391.1 GAP87145.1 - 2.2e-08 33.7 0.1 6.6e-08 32.2 0.1 1.9 1 0 0 1 1 1 1 HNH endonuclease HET PF06985.6 GAP87146.1 - 1.5e-29 102.9 0.6 3.6e-29 101.6 0.4 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NUDIX PF00293.23 GAP87147.1 - 1.8e-05 24.3 3.5 3.6e-05 23.4 2.5 1.7 1 1 0 1 1 1 1 NUDIX domain ThiF PF00899.16 GAP87148.1 - 5.6e-10 39.1 0.8 1.1e-09 38.1 0.6 1.5 1 0 0 1 1 1 1 ThiF family Ldh_1_N PF00056.18 GAP87148.1 - 0.0056 16.5 0.1 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain ApbA PF02558.11 GAP87148.1 - 0.035 13.5 0.3 0.076 12.4 0.2 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 GAP87148.1 - 0.15 12.0 1.2 0.56 10.2 0.1 2.6 2 1 1 3 3 3 0 TrkA-N domain GIDA PF01134.17 GAP87148.1 - 0.54 9.0 2.4 0.87 8.3 0.3 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Carb_anhydrase PF00194.16 GAP87149.1 - 2.2e-22 79.2 0.0 2.8e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Lipase3_N PF03893.11 GAP87150.1 - 0.00022 20.9 0.2 0.0048 16.6 0.1 2.4 1 1 1 2 2 2 1 Lipase 3 N-terminal region PAP_assoc PF03828.14 GAP87151.1 - 7.5e-17 61.0 0.2 1.9e-16 59.7 0.1 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 GAP87151.1 - 2.7e-06 27.6 0.0 5.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain NAD_binding_10 PF13460.1 GAP87151.1 - 0.36 10.8 0.7 2.9 7.8 0.0 2.2 2 0 0 2 2 2 0 NADH(P)-binding AhpC-TSA_2 PF13911.1 GAP87152.1 - 2.3e-12 46.8 0.8 7e-12 45.2 0.6 1.7 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 GAP87152.1 - 1e-05 25.1 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 GAP87152.1 - 0.0013 18.2 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Redoxin DUF4298 PF14131.1 GAP87153.1 - 0.063 13.1 4.2 0.077 12.8 0.5 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4298) DUF914 PF06027.7 GAP87155.1 - 2.8e-98 328.8 20.0 3.8e-98 328.4 13.8 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 GAP87155.1 - 1.1e-06 28.6 13.3 1.1e-06 28.6 9.2 2.7 2 1 1 3 3 3 1 EamA-like transporter family UAA PF08449.6 GAP87155.1 - 0.054 12.3 19.1 0.073 11.9 13.2 1.1 1 0 0 1 1 1 0 UAA transporter family FUSC-like PF12805.2 GAP87155.1 - 5.2 5.9 8.5 0.27 10.1 1.3 2.1 2 1 0 2 2 2 0 FUSC-like inner membrane protein yccS SIR2 PF02146.12 GAP87157.1 - 4e-53 179.7 0.0 5.4e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 GAP87157.1 - 0.025 14.3 0.1 1.6 8.5 0.0 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DUF218 PF02698.12 GAP87157.1 - 0.074 12.5 0.0 0.21 11.0 0.0 1.7 1 0 0 1 1 1 0 DUF218 domain Mem_trans PF03547.13 GAP87158.1 - 1.3e-58 198.1 0.3 1.7e-58 197.7 0.2 1.0 1 0 0 1 1 1 1 Membrane transport protein Pkinase PF00069.20 GAP87159.1 - 4.2e-47 160.4 0.0 6.6e-44 150.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAP87159.1 - 4.5e-31 107.8 0.0 1.1e-29 103.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP87159.1 - 0.00018 20.6 0.0 0.00028 19.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 GAP87159.1 - 0.0019 17.1 0.1 0.0033 16.2 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 GAP87159.1 - 0.085 11.6 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 GAP87159.1 - 0.17 11.6 0.0 0.44 10.2 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family SUR7 PF06687.7 GAP87160.1 - 8.2e-33 113.7 3.5 1e-32 113.4 2.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF973 PF06157.6 GAP87160.1 - 0.2 10.6 1.9 0.31 9.9 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Amastin PF07344.6 GAP87160.1 - 0.38 10.3 15.5 0.065 12.8 8.1 1.6 2 0 0 2 2 2 0 Amastin surface glycoprotein Claudin_2 PF13903.1 GAP87160.1 - 2.2 7.9 22.4 0.18 11.4 10.6 2.1 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF4328 PF14219.1 GAP87160.1 - 3.5 6.8 8.0 0.2 10.9 1.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4328) DNA_methylase PF00145.12 GAP87161.1 - 6.5e-35 120.8 0.0 4.7e-22 78.5 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase Methyltransf_26 PF13659.1 GAP87161.1 - 0.031 14.3 0.1 0.065 13.2 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 GAP87161.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain MFS_1 PF07690.11 GAP87162.1 - 4e-33 114.6 56.8 1.5e-29 102.7 27.8 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAP87162.1 - 2.4e-10 39.2 10.9 2.4e-10 39.2 7.6 2.2 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAP87162.1 - 1.8e-09 36.7 13.9 1.8e-09 36.7 9.7 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 GAP87162.1 - 0.21 9.5 11.1 0.037 12.0 1.3 2.5 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF3328 PF11807.3 GAP87163.1 - 1.3e-20 73.9 0.0 1.8e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 GAP87164.1 - 6.6e-35 120.7 2.3 1.6e-34 119.5 1.6 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 GAP87165.1 - 1.7e-31 109.6 0.5 2.2e-31 109.2 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3741 PF12552.3 GAP87166.1 - 0.0091 15.7 0.0 69 3.2 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3741) HisKA_3 PF07730.8 GAP87166.1 - 0.066 13.5 0.0 2.8e+02 1.9 0.0 3.9 4 0 0 4 4 4 0 Histidine kinase Complex1_30kDa PF00329.14 GAP87166.1 - 0.14 12.3 0.0 1.3e+02 2.9 0.0 3.3 1 1 3 4 4 4 0 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF3755 PF12579.3 GAP87166.1 - 0.68 9.3 7.6 29 4.1 0.1 3.9 1 1 3 4 4 4 0 Protein of unknown function (DUF3755) DUF3328 PF11807.3 GAP87167.1 - 2e-30 106.1 0.4 2.7e-30 105.6 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Ank_2 PF12796.2 GAP87168.1 - 2.3e-146 476.5 25.2 5.3e-14 52.3 0.0 16.4 5 4 11 16 16 16 16 Ankyrin repeats (3 copies) Ank PF00023.25 GAP87168.1 - 2.4e-113 364.7 53.7 4.7e-08 32.4 0.1 28.2 28 1 0 28 28 28 22 Ankyrin repeat Ank_4 PF13637.1 GAP87168.1 - 7e-101 329.0 28.3 1.6e-09 38.0 0.2 19.8 11 7 12 23 23 23 19 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP87168.1 - 7.7e-94 305.6 44.9 3.7e-09 36.5 0.2 22.6 12 7 14 26 26 26 21 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP87168.1 - 3.1e-81 259.0 38.4 0.0011 18.9 0.0 26.7 27 0 0 27 27 27 20 Ankyrin repeat SPRY PF00622.23 GAP87168.1 - 3.8e-15 56.0 0.9 3.1e-14 53.1 0.5 2.6 2 0 0 2 2 2 1 SPRY domain DUF1182 PF06681.8 GAP87168.1 - 0.12 11.5 0.4 0.25 10.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1182) Pectinesterase PF01095.14 GAP87169.1 - 1.2e-24 86.4 0.2 2.9e-20 72.0 0.1 2.1 2 0 0 2 2 2 2 Pectinesterase Glyco_hydro_28 PF00295.12 GAP87170.1 - 3.6e-44 151.0 10.6 5.6e-44 150.4 7.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pirin PF02678.11 GAP87171.1 - 3.1e-23 81.6 1.3 1.2e-22 79.8 0.9 1.9 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.6 GAP87171.1 - 0.00018 20.9 3.3 0.019 14.4 0.2 3.4 2 1 0 2 2 2 2 Cupin domain HhH-GPD PF00730.20 GAP87172.1 - 3.7e-09 36.8 0.1 2e-08 34.5 0.0 2.2 2 1 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein SEN1_N PF12726.2 GAP87173.1 - 2.5e-153 511.8 3.1 3.7e-153 511.2 2.2 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 GAP87173.1 - 8.3e-69 231.7 0.3 8.3e-69 231.7 0.2 1.8 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 GAP87173.1 - 9.5e-63 211.2 0.0 1.5e-61 207.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 GAP87173.1 - 6.8e-11 41.7 0.3 2.9e-10 39.7 0.2 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 GAP87173.1 - 1.3e-09 37.9 0.2 5.5e-07 29.3 0.1 2.7 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 GAP87173.1 - 5.1e-06 26.1 0.7 0.0046 16.4 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 GAP87173.1 - 3.4e-05 23.3 1.2 0.025 13.9 0.0 3.3 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain GvpH PF05455.6 GAP87173.1 - 0.012 15.2 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 GvpH AAA_25 PF13481.1 GAP87173.1 - 0.017 14.5 0.1 0.039 13.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 GAP87173.1 - 0.034 13.6 0.5 0.22 11.0 0.0 2.4 2 1 0 2 2 2 0 DEAD/DEAH box helicase MFS_1 PF07690.11 GAP87174.1 - 4e-17 61.9 30.8 2.7e-16 59.2 18.4 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF1576 PF07613.6 GAP87174.1 - 0.028 13.9 0.3 0.028 13.9 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1576) MFS_2 PF13347.1 GAP87174.1 - 0.43 8.9 20.7 0.05 12.0 3.3 3.0 2 1 1 3 3 3 0 MFS/sugar transport protein 2OG-FeII_Oxy PF03171.15 GAP87175.1 - 5.4e-16 58.7 0.0 9e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 GAP87175.1 - 1.2e-09 38.7 0.0 2.3e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal APH PF01636.18 GAP87176.1 - 9.3e-12 45.1 0.0 1.7e-11 44.3 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 GAP87176.1 - 9.8e-08 31.4 0.1 1.8e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Ecdysteroid kinase Choline_kinase PF01633.15 GAP87176.1 - 0.0016 18.0 0.1 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase FAD_binding_3 PF01494.14 GAP87177.1 - 4.8e-23 81.7 0.0 1.1e-22 80.6 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 GAP87177.1 - 0.00041 19.3 0.0 3.6 6.3 0.0 3.0 3 0 0 3 3 3 3 Lycopene cyclase protein Pyr_redox PF00070.22 GAP87177.1 - 0.0051 17.1 0.2 0.024 15.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 GAP87177.1 - 0.021 13.9 0.0 4.8 6.1 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAP87177.1 - 0.036 14.1 0.0 0.13 12.2 0.0 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF4516 PF14990.1 GAP87178.1 - 0.069 12.7 0.2 0.17 11.4 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) HET PF06985.6 GAP87180.1 - 1.4e-31 109.5 0.0 2.4e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF815 PF05673.8 GAP87180.1 - 0.19 10.6 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) VSP PF03302.8 GAP87181.1 - 0.0019 16.8 0.8 0.0028 16.3 0.6 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Lysis_S PF04971.7 GAP87181.1 - 0.12 12.1 0.4 0.81 9.4 0.1 2.2 2 0 0 2 2 2 0 Lysis protein S PCI PF01399.22 GAP87182.1 - 9.6e-21 74.0 0.0 2.9e-20 72.5 0.0 1.8 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 GAP87182.1 - 0.042 13.6 0.6 0.15 11.8 0.0 2.2 3 0 0 3 3 3 0 COP9 signalosome, subunit CSN8 EST1_DNA_bind PF10373.4 GAP87182.1 - 0.063 12.4 0.6 0.69 9.0 0.0 2.3 2 0 0 2 2 2 0 Est1 DNA/RNA binding domain NIPSNAP PF07978.8 GAP87183.1 - 3e-38 129.8 4.7 9.6e-30 102.5 0.1 2.6 3 0 0 3 3 3 2 NIPSNAP Rogdi_lz PF10259.4 GAP87184.1 - 1.4e-69 234.2 0.0 2.9e-69 233.2 0.0 1.5 1 1 0 1 1 1 1 Rogdi leucine zipper containing protein Rpp20 PF12328.3 GAP87185.1 - 2.3e-22 79.1 0.6 3.5e-22 78.6 0.4 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 GAP87185.1 - 3.2e-12 45.8 0.2 5.2e-12 45.1 0.2 1.4 1 0 0 1 1 1 1 Alba DAO PF01266.19 GAP87186.1 - 1.6e-42 145.7 0.0 2.5e-42 145.0 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 GAP87186.1 - 1.4e-06 27.4 0.0 1.7e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 GAP87186.1 - 1.4e-05 24.2 0.0 0.0013 17.7 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAP87186.1 - 3.2e-05 23.7 0.0 0.069 12.9 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 GAP87186.1 - 0.00033 20.5 0.0 0.022 14.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP87186.1 - 0.0011 18.9 0.0 0.0032 17.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAP87186.1 - 0.0028 17.7 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAP87186.1 - 0.018 13.6 0.0 1.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.13 GAP87186.1 - 0.059 13.3 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain GMC_oxred_N PF00732.14 GAP87186.1 - 0.066 12.3 0.0 6.8 5.7 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase GMC_oxred_N PF00732.14 GAP87187.1 - 6.7e-27 94.4 0.0 1.1e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAP87187.1 - 1.4e-22 80.5 0.2 2.6e-22 79.6 0.2 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAP87187.1 - 2e-07 30.2 0.2 0.0012 17.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAP87187.1 - 4e-05 22.6 0.8 0.00048 19.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAP87187.1 - 0.00014 21.8 0.0 0.00039 20.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAP87187.1 - 0.00087 19.2 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAP87187.1 - 0.016 14.2 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 GAP87187.1 - 0.035 12.5 0.0 0.089 11.2 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 GAP87187.1 - 0.064 12.3 0.1 0.13 11.3 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 GAP87187.1 - 0.087 12.8 0.1 0.52 10.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CRAL_TRIO PF00650.15 GAP87188.1 - 1.5e-37 128.5 0.0 2.3e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAP87188.1 - 2.4e-09 37.1 0.0 1.1e-08 35.1 0.0 2.3 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 GAP87188.1 - 2.5e-06 27.4 0.0 3.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain BNIP3 PF06553.7 GAP87188.1 - 0.043 13.1 1.1 0.072 12.4 0.8 1.3 1 0 0 1 1 1 0 BNIP3 AF-4 PF05110.8 GAP87188.1 - 8.4 4.1 7.7 12 3.6 5.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Pyr_redox_3 PF13738.1 GAP87189.1 - 2.3e-22 80.0 0.0 3.6e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAP87189.1 - 8.2e-11 40.7 0.1 2.6e-09 35.8 0.0 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 GAP87189.1 - 2.6e-10 40.1 0.0 2.5e-09 36.9 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAP87189.1 - 4.3e-09 35.8 0.0 1.3e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 Thi4 family K_oxygenase PF13434.1 GAP87189.1 - 2.4e-05 23.4 0.1 0.0009 18.2 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 GAP87189.1 - 8.5e-05 21.6 0.0 8.5e-05 21.6 0.0 2.9 2 1 0 3 3 3 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 GAP87189.1 - 0.0011 18.1 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 GAP87189.1 - 0.0012 18.7 2.2 0.32 10.8 0.1 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAP87189.1 - 0.0018 17.2 1.2 0.0071 15.2 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 GAP87189.1 - 0.0045 15.9 0.5 0.028 13.3 0.0 2.2 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_oxidored PF12831.2 GAP87189.1 - 0.016 14.3 0.2 0.031 13.3 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAP87189.1 - 0.076 13.4 0.1 9.2 6.7 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAP87189.1 - 0.13 11.1 1.0 0.24 10.2 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 GAP87189.1 - 1.8 8.3 5.1 2.8 7.6 0.1 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding Abhydrolase_3 PF07859.8 GAP87190.1 - 5.5e-29 101.2 0.0 7e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 GAP87190.1 - 4.6e-12 45.2 0.0 8.1e-12 44.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 GAP87190.1 - 1.8e-05 24.5 0.2 2.7e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 GAP87190.1 - 0.0079 14.9 0.1 0.021 13.5 0.0 1.7 2 0 0 2 2 2 1 Carboxylesterase family DUF2156 PF09924.4 GAP87190.1 - 0.036 12.8 0.0 0.13 11.0 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2156) adh_short PF00106.20 GAP87191.1 - 6.9e-30 104.1 0.1 1.2e-29 103.3 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP87191.1 - 6e-10 39.3 0.1 8.8e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP87191.1 - 1.2e-09 38.0 0.7 4.1e-09 36.3 0.5 1.8 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAP87191.1 - 2.2e-05 24.5 0.0 4.6e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAP87191.1 - 5.7e-05 22.6 0.0 0.0001 21.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAP87191.1 - 0.00022 20.0 0.0 0.00031 19.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 2-Hacid_dh_C PF02826.14 GAP87191.1 - 0.0004 19.5 0.0 0.00062 18.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1776 PF08643.5 GAP87191.1 - 0.012 14.7 0.1 0.021 13.9 0.1 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Zn_clus PF00172.13 GAP87192.1 - 2.1e-09 37.1 9.7 5.5e-09 35.7 6.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAP87192.1 - 0.00026 19.7 0.3 0.00039 19.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 GAP87193.1 - 2.7e-73 247.0 0.0 3.5e-73 246.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_18 PF12847.2 GAP87194.1 - 3.9e-09 37.0 0.0 7.4e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP87194.1 - 8.7e-09 35.1 0.0 1.5e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP87194.1 - 2e-06 28.1 0.0 3.6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP87194.1 - 8.6e-06 25.5 0.0 1.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP87194.1 - 0.00073 18.7 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 GAP87194.1 - 0.0012 18.9 0.0 0.0024 17.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 GAP87194.1 - 0.0023 17.2 0.0 0.0087 15.3 0.0 1.8 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_11 PF08241.7 GAP87194.1 - 0.0043 17.5 0.0 0.0082 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP87194.1 - 0.043 14.1 0.0 0.15 12.4 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Glyco_hydro_31 PF01055.21 GAP87195.1 - 8.4e-133 443.4 1.9 8.3e-94 314.9 0.5 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 GAP87195.1 - 1.8e-07 30.8 0.2 7.2e-07 28.9 0.1 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like Semialdhyde_dh PF01118.19 GAP87196.1 - 2e-27 95.9 0.0 4.8e-27 94.6 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 GAP87196.1 - 0.0039 17.0 0.0 0.013 15.3 0.0 2.0 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus DASH_Spc19 PF08287.6 GAP87198.1 - 4.3e-41 140.0 0.5 5.9e-41 139.6 0.3 1.2 1 0 0 1 1 1 1 Spc19 COG5 PF10392.4 GAP87198.1 - 0.0031 17.4 1.0 1.5 8.7 0.1 2.6 2 1 1 3 3 3 2 Golgi transport complex subunit 5 Surfac_D-trimer PF09006.6 GAP87198.1 - 0.5 10.1 2.4 7.1 6.4 0.6 2.7 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation DASH_Spc34 PF08657.5 GAP87198.1 - 3.3 7.3 6.6 9 5.8 0.2 2.1 1 1 1 2 2 2 0 DASH complex subunit Spc34 SH3_1 PF00018.23 GAP87199.1 - 4.7e-09 35.4 0.1 8.8e-09 34.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAP87199.1 - 3.2e-07 29.7 0.0 6.1e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 GAP87199.1 - 2.3e-06 27.0 0.0 4.5e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF2591 PF10765.4 GAP87199.1 - 0.094 12.9 0.1 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2591) DUF1282 PF06930.7 GAP87199.1 - 0.22 11.1 7.5 0.32 10.6 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Caprin-1_C PF12287.3 GAP87200.1 - 0.19 11.1 0.2 0.26 10.6 0.2 1.1 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term Aa_trans PF01490.13 GAP87201.1 - 1.1e-93 313.9 15.7 1.4e-93 313.5 10.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 GAP87201.1 - 0.0001 21.2 18.9 0.0002 20.2 13.1 1.5 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Lyase_1 PF00206.15 GAP87202.1 - 1.2e-109 366.3 0.0 1.6e-109 365.9 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 GAP87202.1 - 5.8e-20 71.1 0.0 1.5e-19 69.7 0.0 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus WD40 PF00400.27 GAP87203.1 - 2.9e-23 80.8 9.1 2.8e-06 26.9 0.0 7.8 8 0 0 8 8 8 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 GAP87203.1 - 0.0011 18.4 0.0 0.066 12.7 0.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.1 GAP87203.1 - 0.058 12.4 0.0 1.1 8.2 0.0 2.7 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Ubiq-Cytc-red_N PF09165.5 GAP87203.1 - 0.16 12.3 0.0 1.2 9.5 0.0 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal Phosphonate-bd PF12974.2 GAP87204.1 - 3.7e-11 42.8 0.0 5.2e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein PKI PF02827.11 GAP87204.1 - 0.12 12.4 1.0 5.9 7.0 0.0 2.6 3 0 0 3 3 3 0 cAMP-dependent protein kinase inhibitor AMP-binding PF00501.23 GAP87205.1 - 2.4e-83 279.8 0.1 3.1e-83 279.4 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAP87205.1 - 2.6e-15 57.1 1.1 2.6e-15 57.1 0.7 2.4 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Ribosomal_S14 PF00253.16 GAP87207.1 - 3e-16 58.5 0.6 6.8e-16 57.3 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Cohesin_load PF10345.4 GAP87207.1 - 0.11 10.7 0.0 0.13 10.4 0.0 1.1 1 0 0 1 1 1 0 Cohesin loading factor Arb2 PF09757.4 GAP87208.1 - 2.7e-14 52.9 0.0 4.2e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain AIG2 PF06094.7 GAP87210.1 - 5e-05 23.7 0.0 6.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family DnaA_N PF11638.3 GAP87210.1 - 0.046 13.2 0.0 0.13 11.8 0.0 1.7 1 1 1 2 2 2 0 DnaA N-terminal domain AIG2_2 PF13772.1 GAP87210.1 - 0.13 12.4 0.0 0.29 11.2 0.0 1.9 1 1 0 1 1 1 0 AIG2-like family AIG2 PF06094.7 GAP87211.1 - 3.2e-06 27.5 0.0 6.2e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 AIG2-like family AIG2_2 PF13772.1 GAP87211.1 - 3.9e-06 26.8 0.0 0.00023 21.2 0.0 2.2 2 0 0 2 2 2 1 AIG2-like family Pro-rich_19 PF15455.1 GAP87211.1 - 0.14 11.1 0.1 0.2 10.6 0.1 1.1 1 0 0 1 1 1 0 Proline-rich 19 DUF2062 PF09835.4 GAP87212.1 - 0.023 14.3 0.1 0.049 13.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) MMPL PF03176.10 GAP87214.1 - 0.0067 15.1 22.4 0.0084 14.8 15.5 1.1 1 0 0 1 1 1 1 MMPL family TrbL PF04610.9 GAP87214.1 - 0.26 10.9 21.0 0.3 10.7 14.6 1.1 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein DUF3043 PF11241.3 GAP87214.1 - 2.3 7.7 10.5 4.2 6.9 7.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF1129 PF06570.6 GAP87214.1 - 2.7 7.2 12.4 3.6 6.8 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) RhoGAP PF00620.22 GAP87215.1 - 7.5e-50 168.4 0.0 2e-49 167.0 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 GAP87215.1 - 3.7e-16 59.0 1.8 1.6e-15 57.0 0.1 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Phage_glycop_gL PF11108.3 GAP87215.1 - 0.085 12.8 0.2 4.5 7.2 0.0 2.6 2 0 0 2 2 2 0 Viral glycoprotein L UPF0139 PF03669.8 GAP87216.1 - 6.4e-07 28.8 0.0 8.4e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Med12 PF09497.5 GAP87217.1 - 5.9e-28 96.6 1.2 1.1e-27 95.7 0.2 2.1 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 PQ-loop PF04193.9 GAP87218.1 - 3.5e-37 125.7 15.1 7.9e-20 70.1 0.9 2.7 3 0 0 3 3 3 2 PQ loop repeat S1-P1_nuclease PF02265.11 GAP87219.1 - 7.2e-74 248.5 0.3 8.1e-74 248.4 0.2 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Kelch_5 PF13854.1 GAP87221.1 - 7.3e-38 127.9 7.2 1.3e-10 40.9 0.2 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 GAP87221.1 - 2.6e-37 126.3 8.2 3.9e-08 32.9 0.3 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 GAP87221.1 - 2.7e-33 113.3 9.9 7e-08 32.4 0.0 6.9 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.1 GAP87221.1 - 1e-29 101.4 9.1 1.3e-10 41.0 0.5 6.4 4 1 2 6 6 6 6 Kelch motif Kelch_1 PF01344.20 GAP87221.1 - 1.3e-29 101.4 6.0 8.5e-10 38.0 0.2 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 GAP87221.1 - 1.8e-22 78.1 6.4 6.7e-08 31.9 0.2 6.6 6 0 0 6 6 6 5 Kelch motif RAG2 PF03089.9 GAP87221.1 - 0.0015 17.3 0.1 0.1 11.2 0.0 3.3 4 0 0 4 4 4 1 Recombination activating protein 2 Raptor_N PF14538.1 GAP87222.1 - 2.4e-65 219.1 0.0 2.4e-65 219.1 0.0 1.9 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 GAP87222.1 - 1.3e-06 27.9 0.4 7.8 6.5 0.0 5.2 4 0 0 4 4 4 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 GAP87222.1 - 0.00045 19.9 0.1 0.36 10.6 0.1 2.8 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region HEAT_2 PF13646.1 GAP87222.1 - 0.0015 18.7 0.3 0.04 14.2 0.0 3.2 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 GAP87222.1 - 0.2 11.8 9.7 5.1 7.4 0.0 5.1 6 0 0 6 6 6 0 HEAT repeat CorA PF01544.13 GAP87224.1 - 2.4e-12 46.4 0.8 5.3e-12 45.3 0.1 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Hydrophobin_2 PF06766.6 GAP87227.1 - 6.6e-30 102.5 7.9 8.8e-30 102.1 5.5 1.2 1 0 0 1 1 1 1 Fungal hydrophobin DUF4066 PF13278.1 GAP87228.1 - 1.6e-29 102.3 0.0 1.9e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 GAP87228.1 - 4.9e-14 52.0 0.0 7.3e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF2953 PF11167.3 GAP87228.1 - 0.096 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) ApbA PF02558.11 GAP87229.1 - 5.3e-24 84.3 0.0 8.5e-24 83.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 GAP87229.1 - 6.6e-22 77.8 0.0 1e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DASH_Hsk3 PF08227.6 GAP87230.1 - 3.3e-20 72.0 4.1 4.3e-20 71.6 2.8 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like PTPLA PF04387.9 GAP87231.1 - 4e-37 127.1 1.7 2.7e-36 124.4 1.2 2.2 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Rpr2 PF04032.11 GAP87233.1 - 3.5e-20 71.6 0.5 6.4e-20 70.8 0.3 1.5 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-BED PF02892.10 GAP87233.1 - 0.053 13.2 1.7 8.8 6.1 0.1 3.2 3 0 0 3 3 3 0 BED zinc finger DEAD PF00270.24 GAP87234.1 - 2e-37 128.2 0.0 3.4e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP87234.1 - 2.7e-24 84.8 0.0 4.2e-23 80.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAP87234.1 - 1e-05 25.4 0.1 4.4e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 GAP87234.1 - 0.03 13.3 0.1 0.2 10.6 0.0 2.0 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Mg_trans_NIPA PF05653.9 GAP87235.1 - 9e-16 57.6 4.6 1.4e-15 57.0 3.2 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 GAP87235.1 - 0.001 19.0 3.4 0.001 19.0 2.4 3.3 2 2 1 3 3 3 1 EamA-like transporter family ESX-1_EspG PF14011.1 GAP87235.1 - 0.022 14.0 0.6 0.037 13.2 0.4 1.3 1 0 0 1 1 1 0 EspG family vATP-synt_E PF01991.13 GAP87236.1 - 4.2e-63 212.2 12.1 4.7e-63 212.0 8.4 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit MA3 PF02847.12 GAP87237.1 - 0.065 12.9 0.1 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 MA3 domain E1-E2_ATPase PF00122.15 GAP87238.1 - 3.1e-12 46.0 0.0 1.7e-11 43.6 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 GAP87238.1 - 4.4e-12 45.8 0.0 1.5e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 GAP87238.1 - 1.6e-10 41.4 0.0 4.4e-10 40.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAP87238.1 - 7.1e-10 39.6 2.4 1.8e-07 31.8 1.6 3.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAP87238.1 - 0.012 15.2 0.6 0.027 14.0 0.4 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Aldedh PF00171.17 GAP87239.1 - 2.1e-115 385.6 0.0 2.4e-115 385.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SMC_N PF02463.14 GAP87240.1 - 1.3e-25 89.9 0.0 2.3e-25 89.1 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 GAP87240.1 - 1.8e-11 44.7 22.1 1.8e-11 44.7 15.3 5.7 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 GAP87240.1 - 1.2e-05 25.4 0.0 0.0022 18.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain IncA PF04156.9 GAP87240.1 - 0.0018 17.9 74.6 0.0089 15.6 0.3 6.4 4 2 2 6 6 6 3 IncA protein AAA_29 PF13555.1 GAP87240.1 - 0.0063 16.0 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 GAP87240.1 - 0.019 14.3 0.4 0.12 11.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 GAP87240.1 - 0.027 14.6 0.0 0.12 12.6 0.0 2.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAP87240.1 - 0.059 13.5 0.8 1.2 9.2 0.0 3.1 2 0 0 2 2 2 0 AAA domain CCP_MauG PF03150.9 GAP87240.1 - 4.2 7.6 6.8 1.5 9.1 0.6 2.8 2 1 1 3 3 3 0 Di-haem cytochrome c peroxidase Pkinase PF00069.20 GAP87241.1 - 2.1e-69 233.5 0.0 3.9e-69 232.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP87241.1 - 1.7e-33 115.7 0.0 1.4e-30 106.2 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAP87241.1 - 4.8e-06 25.7 0.0 8.7e-06 24.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAP87241.1 - 0.002 17.8 0.0 0.0085 15.8 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAP87241.1 - 0.0096 15.5 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Malate_synthase PF01274.17 GAP87242.1 - 5.2e-235 780.3 0.0 5.9e-235 780.2 0.0 1.0 1 0 0 1 1 1 1 Malate synthase PEHE PF15275.1 GAP87243.1 - 0.46 10.9 3.6 0.51 10.7 0.1 2.1 2 0 0 2 2 2 0 PEHE domain Macoilin PF09726.4 GAP87243.1 - 5.4 5.1 8.5 7.6 4.6 5.9 1.2 1 0 0 1 1 1 0 Transmembrane protein Clr5 PF14420.1 GAP87244.1 - 2.3e-22 78.6 0.8 3e-22 78.2 0.6 1.1 1 0 0 1 1 1 1 Clr5 domain Robl_LC7 PF03259.12 GAP87246.1 - 1e-08 34.5 0.0 3.5e-07 29.6 0.0 2.1 2 0 0 2 2 2 2 Roadblock/LC7 domain Ipi1_N PF12333.3 GAP87247.1 - 1.2e-15 57.2 0.0 5.8e-15 55.1 0.0 2.0 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation HEAT_2 PF13646.1 GAP87247.1 - 0.013 15.7 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 HEAT repeats Cyclin PF08613.6 GAP87248.1 - 2.7e-14 53.8 0.2 2e-13 51.0 0.0 2.2 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 GAP87248.1 - 0.00052 19.5 0.0 0.0012 18.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain AAA PF00004.24 GAP87251.1 - 3.1e-18 66.2 0.0 8.3e-18 64.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Ank_2 PF12796.2 GAP87251.1 - 5.1e-09 36.3 0.0 1.7e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAP87251.1 - 1.3e-08 34.2 0.2 0.011 15.5 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat AAA_33 PF13671.1 GAP87251.1 - 4.3e-06 26.6 0.1 0.00015 21.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Ank_4 PF13637.1 GAP87251.1 - 9.6e-06 25.9 0.0 4.7e-05 23.7 0.0 2.3 2 0 0 2 2 1 1 Ankyrin repeats (many copies) AAA_22 PF13401.1 GAP87251.1 - 8.1e-05 22.7 0.2 0.0025 17.9 0.0 2.7 1 1 1 2 2 2 1 AAA domain Ank_3 PF13606.1 GAP87251.1 - 8.9e-05 22.3 0.0 0.45 10.9 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat AAA_17 PF13207.1 GAP87251.1 - 0.00012 22.9 0.2 0.00085 20.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain Ank_5 PF13857.1 GAP87251.1 - 0.00033 20.8 0.0 0.0011 19.0 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) AAA_18 PF13238.1 GAP87251.1 - 0.0006 20.1 0.1 0.0064 16.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 GAP87251.1 - 0.0015 18.2 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 GAP87251.1 - 0.008 15.6 0.0 0.023 14.1 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 GAP87251.1 - 0.022 14.7 0.1 0.078 12.9 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_2 PF07724.9 GAP87251.1 - 0.092 12.6 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) KaiC PF06745.8 GAP87251.1 - 0.11 11.6 0.9 1 8.4 0.1 2.3 1 1 1 2 2 2 0 KaiC AAA_28 PF13521.1 GAP87251.1 - 0.14 12.0 1.1 2.5 8.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain HET PF06985.6 GAP87252.1 - 4.5e-36 124.0 0.2 4.5e-36 124.0 0.1 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) NAD_binding_2 PF03446.10 GAP87253.1 - 1.1e-38 132.6 0.7 1.6e-38 132.0 0.5 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 GAP87253.1 - 2.8e-23 82.2 0.1 4.5e-23 81.6 0.1 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 GAP87253.1 - 8.5e-07 29.3 0.0 1.9e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.10 GAP87253.1 - 1.3e-06 27.4 0.1 2.3e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 GAP87253.1 - 0.0011 19.1 0.2 0.0023 18.0 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.17 GAP87253.1 - 0.0026 18.2 0.0 0.012 16.1 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold IlvN PF07991.7 GAP87253.1 - 0.004 16.5 0.0 0.0071 15.7 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 GAP87253.1 - 0.0044 16.1 0.0 0.0074 15.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HET PF06985.6 GAP87254.1 - 1.2e-33 116.2 0.7 1.9e-33 115.5 0.5 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 GAP87255.1 - 1.1e-68 231.2 0.0 2e-68 230.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP87255.1 - 2e-50 171.3 0.0 3.5e-50 170.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP87255.1 - 0.002 17.1 0.0 0.0051 15.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like DUF2576 PF10845.3 GAP87255.1 - 0.033 13.3 0.1 0.082 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) Vps23_core PF09454.5 GAP87255.1 - 0.12 12.0 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 Vps23 core domain Med21 PF11221.3 GAP87255.1 - 2.8 7.9 5.6 7.5 6.5 0.8 2.7 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Iso_dh PF00180.15 GAP87257.1 - 1.3e-80 271.0 0.0 1.6e-80 270.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Copine PF07002.11 GAP87257.1 - 0.047 13.4 0.0 3.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Copine DUF1964 PF09244.5 GAP87257.1 - 0.13 12.6 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1964) Acetyltransf_3 PF13302.1 GAP87258.1 - 5.1e-21 75.3 0.1 7e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAP87258.1 - 0.0071 16.3 1.1 0.38 10.8 0.7 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAP87258.1 - 0.0077 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 GAP87258.1 - 0.011 15.6 0.2 0.13 12.1 0.0 2.3 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain SH3_9 PF14604.1 GAP87259.1 - 6e-08 32.1 0.9 1.6e-07 30.7 0.4 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 GAP87259.1 - 0.0043 16.5 0.2 0.011 15.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain G-alpha PF00503.15 GAP87260.1 - 3.4e-128 427.6 0.1 4.1e-128 427.3 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAP87260.1 - 1.2e-15 57.2 0.2 1.5e-10 40.6 0.0 2.7 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAP87260.1 - 0.00034 19.8 0.1 0.32 10.0 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 GAP87260.1 - 0.0014 19.1 0.1 0.95 9.9 0.0 2.8 3 0 0 3 3 3 2 Miro-like protein AAA_29 PF13555.1 GAP87260.1 - 0.04 13.4 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Phosphorylase PF00343.15 GAP87261.1 - 0 1077.6 0.3 0 1077.3 0.2 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Coatomer_b_Cpla PF14806.1 GAP87261.1 - 0.059 13.0 0.1 0.19 11.4 0.1 1.8 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform Pkinase PF00069.20 GAP87263.1 - 7.3e-73 244.9 0.0 9e-73 244.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP87263.1 - 6.3e-32 110.6 0.0 9.2e-32 110.1 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 GAP87263.1 - 8.7e-06 24.9 0.1 3e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 GAP87263.1 - 0.00013 21.0 0.0 0.023 13.6 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 GAP87263.1 - 0.00023 20.9 0.1 0.0012 18.6 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 GAP87263.1 - 0.022 14.0 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Aminotran_3 PF00202.16 GAP87264.1 - 1.8e-16 59.9 0.0 2.3e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Fungal_trans PF04082.13 GAP87265.1 - 2e-58 197.2 0.1 3.4e-58 196.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PfkB PF00294.19 GAP87267.1 - 1.7e-11 43.8 0.1 1.7e-06 27.4 0.4 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase CAP_N PF01213.14 GAP87268.1 - 2e-89 299.9 8.6 1.1e-88 297.5 6.0 1.9 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 GAP87268.1 - 8.5e-57 190.9 4.3 1.1e-56 190.5 3.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 GAP87268.1 - 0.06 12.7 1.4 0.41 10.0 0.5 2.1 1 1 1 2 2 2 0 Tubulin binding cofactor C Carn_acyltransf PF00755.15 GAP87269.1 - 1.8e-175 584.4 0.0 2.1e-175 584.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase AfaD PF05775.7 GAP87269.1 - 0.1 12.5 0.1 1.4 8.9 0.1 2.2 2 0 0 2 2 2 0 Enterobacteria AfaD invasin protein WSC PF01822.14 GAP87270.1 - 3.3e-12 46.1 6.2 1.6e-11 43.9 4.3 2.2 1 0 0 1 1 1 1 WSC domain Glyco_hydro_16 PF00722.16 GAP87270.1 - 2.7e-07 30.0 0.4 5.5e-07 29.0 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Anoctamin PF04547.7 GAP87271.1 - 1.7e-117 392.9 6.2 2.2e-117 392.5 4.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Metallophos_2 PF12850.2 GAP87272.1 - 1.7e-06 27.9 0.0 2.9e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 GAP87272.1 - 4.7e-05 22.8 5.1 0.00029 20.3 3.6 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4360 PF14273.1 GAP87273.1 - 2.6e-16 59.7 1.1 3.3e-16 59.4 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) TFIIIC_delta PF12657.2 GAP87273.1 - 0.016 14.9 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term Pex2_Pex12 PF04757.9 GAP87274.1 - 5.5e-56 189.5 2.1 8.6e-56 188.9 1.4 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 GAP87274.1 - 7.1e-06 25.9 3.2 1.3e-05 25.1 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAP87274.1 - 0.0022 17.8 2.8 0.0035 17.1 2.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 GAP87274.1 - 0.0078 16.0 2.6 0.014 15.2 1.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 GAP87274.1 - 0.014 15.0 2.0 0.021 14.4 1.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAP87274.1 - 0.035 13.7 3.4 0.06 13.0 2.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ArfGap PF01412.13 GAP87275.1 - 1.5e-35 121.5 0.4 3.5e-35 120.3 0.3 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TIM21 PF08294.6 GAP87276.1 - 1.7e-45 154.2 0.0 2.1e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 GAP87276.1 - 7e-08 31.9 0.0 1.1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 NDT80_PhoG PF05224.7 GAP87277.1 - 1e-49 169.0 0.0 1.4e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Pterin_bind PF00809.17 GAP87278.1 - 1e-62 211.2 0.0 2.8e-62 209.8 0.0 1.7 2 1 0 2 2 2 1 Pterin binding enzyme HPPK PF01288.15 GAP87278.1 - 2.9e-40 136.9 0.0 5.6e-40 135.9 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NMO PF03060.10 GAP87279.1 - 2e-68 230.9 0.6 2.7e-68 230.5 0.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 GAP87279.1 - 2.1e-08 33.4 0.8 9.1e-08 31.3 0.6 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 GAP87279.1 - 2.9e-05 23.0 1.5 4.9e-05 22.3 1.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 GAP87279.1 - 0.0083 15.1 0.2 0.013 14.4 0.1 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.12 GAP87279.1 - 0.0087 15.0 2.0 0.019 13.9 1.4 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase Radial_spoke_3 PF06098.6 GAP87279.1 - 0.15 11.0 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Radial spoke protein 3 adh_short PF00106.20 GAP87280.1 - 6.4e-21 74.9 1.6 7.4e-20 71.5 1.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP87280.1 - 1.3e-20 74.2 0.1 3.7e-19 69.4 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP87280.1 - 4.2e-10 39.5 1.8 1.2e-08 34.8 1.3 2.1 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 GAP87280.1 - 0.0021 17.2 0.0 0.0031 16.6 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) HI0933_like PF03486.9 GAP87280.1 - 0.1 11.0 0.6 0.2 10.0 0.4 1.6 1 0 0 1 1 1 0 HI0933-like protein ADH_zinc_N PF00107.21 GAP87280.1 - 0.19 11.3 1.3 0.39 10.2 0.2 2.0 2 0 0 2 2 2 0 Zinc-binding dehydrogenase MIP PF00230.15 GAP87281.1 - 0.012 15.1 0.7 0.017 14.5 0.5 1.2 1 0 0 1 1 1 0 Major intrinsic protein SUR7 PF06687.7 GAP87282.1 - 6.1e-24 84.7 0.2 7e-24 84.5 0.1 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 GAP87282.1 - 1.4 8.7 9.2 0.18 11.6 3.4 1.7 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 MscL PF01741.13 GAP87283.1 - 4.9e-13 49.3 0.7 1.5e-12 47.7 0.5 1.7 1 1 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL Fer4_11 PF13247.1 GAP87283.1 - 0.037 13.9 0.3 0.056 13.3 0.2 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain C1_1 PF00130.17 GAP87283.1 - 0.097 12.4 2.0 0.16 11.7 1.4 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.2 GAP87283.1 - 0.1 12.4 0.4 0.17 11.7 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 GAP87283.1 - 0.12 11.8 0.3 0.21 11.1 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain DUF2339 PF10101.4 GAP87283.1 - 0.16 10.2 0.8 0.22 9.7 0.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) zf-BED PF02892.10 GAP87283.1 - 0.3 10.8 5.1 0.64 9.8 3.5 1.5 1 0 0 1 1 1 0 BED zinc finger Dioxygenase_C PF00775.16 GAP87284.1 - 1.9e-11 43.5 0.0 3.2e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase WD40 PF00400.27 GAP87286.1 - 3.4e-17 61.5 18.7 8.8e-08 31.7 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Tim17 PF02466.14 GAP87287.1 - 9.1e-33 113.0 7.0 1.2e-32 112.6 4.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family p450 PF00067.17 GAP87288.1 - 1e-14 53.9 0.0 1.2e-13 50.4 0.0 2.2 2 1 0 2 2 2 1 Cytochrome P450 3Beta_HSD PF01073.14 GAP87289.1 - 3.4e-29 101.4 0.0 3.3e-28 98.1 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAP87289.1 - 6.4e-17 61.7 0.0 9.2e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAP87289.1 - 2.8e-11 42.8 0.0 1e-09 37.6 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 GAP87289.1 - 2.5e-10 40.5 0.4 5.7e-10 39.3 0.3 1.6 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 GAP87289.1 - 1.5e-08 34.8 0.2 2.4e-07 30.9 0.5 2.7 2 1 0 2 2 2 1 NADH(P)-binding KR PF08659.5 GAP87289.1 - 1.8e-08 34.2 0.0 3.4e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 GAP87289.1 - 4.1e-06 25.8 0.0 8e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Pro_CA PF00484.14 GAP87290.1 - 4.5e-26 91.6 0.0 6.7e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase DUF3605 PF12239.3 GAP87291.1 - 1.4e-57 194.0 2.9 1.7e-57 193.7 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) UDPGP PF01704.13 GAP87292.1 - 2.4e-183 609.4 0.5 2.9e-183 609.1 0.3 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.1 GAP87292.1 - 0.012 14.2 0.3 0.23 9.9 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4301) ING PF12998.2 GAP87293.1 - 1.6e-22 79.7 2.5 2.4e-22 79.2 1.8 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 GAP87293.1 - 9.1e-09 34.8 7.7 1.6e-08 34.0 5.3 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 GAP87293.1 - 0.07 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING-like PF08746.6 GAP87293.1 - 0.23 11.4 2.0 0.4 10.7 1.4 1.4 1 0 0 1 1 1 0 RING-like domain Hist_deacetyl PF00850.14 GAP87294.1 - 1.8e-75 254.1 0.0 2.5e-75 253.6 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain RNA_replicase_B PF03431.8 GAP87294.1 - 0.02 13.1 0.0 0.32 9.1 0.0 2.0 2 0 0 2 2 2 0 RNA replicase, beta-chain Peptidase_M28 PF04389.12 GAP87295.1 - 2e-31 109.1 0.0 4e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 GAP87295.1 - 4.9e-13 48.6 0.2 2.1e-12 46.5 0.0 2.2 2 0 0 2 2 2 1 PA domain Peptidase_M42 PF05343.9 GAP87295.1 - 0.086 11.6 0.0 1.1 7.9 0.0 2.0 1 1 1 2 2 2 0 M42 glutamyl aminopeptidase MFS_1 PF07690.11 GAP87296.1 - 4.2e-08 32.2 29.9 8.2e-05 21.4 8.4 2.8 2 2 0 2 2 2 2 Major Facilitator Superfamily DUF2681 PF10883.3 GAP87296.1 - 0.19 11.9 0.0 0.19 11.9 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) SUN PF03856.8 GAP87297.1 - 3.5e-77 259.0 7.7 4.7e-77 258.6 5.4 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) zf-H2C2_2 PF13465.1 GAP87298.1 - 1.4e-11 44.0 22.5 6.3e-08 32.5 1.8 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 GAP87298.1 - 4.6e-10 39.2 25.7 0.006 16.8 3.2 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP87298.1 - 7.3e-07 29.0 23.2 0.024 14.9 5.4 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 GAP87298.1 - 0.027 14.3 12.6 0.39 10.6 0.0 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAP87298.1 - 0.047 13.8 17.9 1.2 9.3 5.5 3.7 3 1 1 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-CHCC PF10276.4 GAP87298.1 - 0.073 12.9 5.9 1.5 8.7 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger domain zf-Di19 PF05605.7 GAP87298.1 - 0.2 11.8 13.4 1 9.5 6.0 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PyrI_C PF02748.10 GAP87298.1 - 0.54 9.7 2.7 0.42 10.0 0.5 1.8 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DZR PF12773.2 GAP87298.1 - 0.95 9.3 7.1 8.6 6.2 4.9 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_3 PF14369.1 GAP87298.1 - 1.3 9.1 6.4 15 5.6 0.1 3.0 2 1 1 3 3 3 0 zinc-finger zinc-ribbons_6 PF07191.7 GAP87298.1 - 1.3 8.8 5.2 3.3 7.5 1.7 2.3 2 0 0 2 2 2 0 zinc-ribbons zf-C2HC_2 PF13913.1 GAP87298.1 - 2.2 8.0 8.0 0.083 12.5 0.4 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type FYDLN_acid PF09538.5 GAP87298.1 - 4 8.0 7.5 18 5.9 0.8 3.7 2 1 1 3 3 3 0 Protein of unknown function (FYDLN_acid) Zn-ribbon_8 PF09723.5 GAP87298.1 - 4.6 7.2 9.8 22 5.0 2.5 2.9 1 1 2 3 3 3 0 Zinc ribbon domain GAGA PF09237.6 GAP87298.1 - 5.2 6.7 8.1 2.7 7.6 0.8 3.1 1 1 2 3 3 3 0 GAGA factor zf-C2H2_2 PF12756.2 GAP87298.1 - 6.9 6.8 15.9 16 5.6 8.2 2.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) V-ATPase_H_N PF03224.9 GAP87300.1 - 0.024 13.7 0.1 0.035 13.2 0.1 1.2 1 0 0 1 1 1 0 V-ATPase subunit H DUF547 PF04784.9 GAP87300.1 - 0.097 12.5 0.1 0.28 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF547 DUF2890 PF11081.3 GAP87301.1 - 2.7 8.0 5.3 3.9 7.4 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) RecR PF02132.10 GAP87302.1 - 0.063 12.7 0.2 0.087 12.2 0.1 1.5 1 1 0 1 1 1 0 RecR protein 3-HAO PF06052.7 GAP87302.1 - 0.072 12.5 0.0 0.083 12.2 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase Mu-like_Com PF10122.4 GAP87302.1 - 0.26 10.3 1.5 0.34 9.9 1.0 1.5 1 1 0 1 1 1 0 Mu-like prophage protein Com 3-HAO PF06052.7 GAP87303.1 - 1.6e-52 176.9 0.0 7.5e-52 174.7 0.0 1.8 1 1 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 GAP87303.1 - 0.00018 20.9 0.1 0.16 11.5 0.0 2.2 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 GAP87303.1 - 0.00041 19.7 0.0 0.00054 19.4 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_4 PF08007.7 GAP87303.1 - 0.0017 17.6 0.0 0.002 17.4 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein Carb_kinase PF01256.12 GAP87304.1 - 1.9e-52 177.9 0.1 2.6e-52 177.5 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 GAP87304.1 - 0.00027 20.2 0.0 0.0017 17.5 0.0 1.9 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family ATP-synt_ab PF00006.20 GAP87305.1 - 6.2e-70 235.0 0.0 9e-70 234.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 GAP87305.1 - 5.6e-27 94.4 0.1 2.3e-26 92.5 0.1 2.1 1 1 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 GAP87305.1 - 2.2e-15 56.6 2.8 4.8e-15 55.5 1.9 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 GAP87305.1 - 0.0052 16.6 0.8 0.014 15.3 0.4 1.9 2 0 0 2 2 2 1 HAS barrel domain Arch_ATPase PF01637.13 GAP87305.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase HET PF06985.6 GAP87306.1 - 6.1e-05 23.2 0.1 0.00075 19.6 0.0 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AOX PF01786.12 GAP87307.1 - 1.1e-84 283.0 0.1 1.2e-84 282.8 0.0 1.0 1 0 0 1 1 1 1 Alternative oxidase ISK_Channel PF02060.10 GAP87307.1 - 0.077 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Slow voltage-gated potassium channel Aminotran_4 PF01063.14 GAP87308.1 - 1.8e-23 83.2 0.0 2.5e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Glyco_transf_20 PF00982.16 GAP87309.1 - 7e-160 532.5 0.0 9.5e-160 532.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 GAP87309.1 - 2.2e-42 144.5 0.0 3.6e-42 143.9 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase WD40 PF00400.27 GAP87310.1 - 1.7e-72 236.8 27.9 4.6e-10 38.9 0.0 9.2 8 1 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 GAP87310.1 - 1.3e-08 34.7 0.0 0.00029 20.6 0.0 3.1 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 GAP87310.1 - 7.1e-06 24.4 0.6 0.03 12.4 0.0 3.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 NLE PF08154.7 GAP87310.1 - 6.9e-05 22.7 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Proteasome_A_N PF10584.4 GAP87310.1 - 0.021 14.1 1.1 0.93 8.8 0.0 3.4 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature PQQ PF01011.16 GAP87310.1 - 0.035 13.6 0.1 14 5.4 0.0 3.1 2 0 0 2 2 2 0 PQQ enzyme repeat DUF3560 PF12083.3 GAP87310.1 - 0.11 12.5 0.4 0.28 11.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3560) MutS_V PF00488.16 GAP87311.1 - 2.4e-75 252.9 0.0 3.6e-75 252.3 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 GAP87311.1 - 1.7e-31 109.5 2.6 1.7e-31 109.5 1.8 1.7 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 GAP87311.1 - 2.5e-05 24.3 0.3 6.7e-05 22.9 0.2 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 GAP87311.1 - 0.00016 21.7 0.1 0.00073 19.6 0.0 2.2 2 0 0 2 2 2 1 MutS domain II AAA_14 PF13173.1 GAP87311.1 - 0.036 13.9 0.0 0.14 12.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain B1 PF02246.10 GAP87311.1 - 0.093 12.5 0.4 0.35 10.7 0.1 2.0 2 0 0 2 2 2 0 Protein L b1 domain FAD_binding_3 PF01494.14 GAP87312.1 - 2.3e-74 250.5 0.0 4.3e-74 249.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 GAP87312.1 - 1.4e-07 31.8 0.1 8.6e-07 29.2 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAP87312.1 - 3.5e-07 29.4 0.3 0.00042 19.3 0.0 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAP87312.1 - 1.4e-06 28.2 0.0 3.3e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAP87312.1 - 1.2e-05 24.4 0.0 5.1e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 GAP87312.1 - 0.00013 20.5 0.1 0.00042 18.9 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 GAP87312.1 - 0.00022 20.2 0.3 0.0016 17.4 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 GAP87312.1 - 0.0006 19.7 0.0 0.0028 17.6 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAP87312.1 - 0.0006 20.1 0.0 0.033 14.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAP87312.1 - 0.00081 18.5 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family TrkA_N PF02254.13 GAP87312.1 - 0.0013 18.7 0.0 0.0034 17.3 0.0 1.8 2 0 0 2 2 1 1 TrkA-N domain NAD_binding_9 PF13454.1 GAP87312.1 - 0.0016 18.2 0.0 0.0035 17.1 0.0 1.6 1 1 0 1 1 1 1 FAD-NAD(P)-binding SE PF08491.5 GAP87312.1 - 0.0017 17.2 0.0 0.0036 16.1 0.0 1.5 1 1 0 1 1 1 1 Squalene epoxidase FAD_oxidored PF12831.2 GAP87312.1 - 0.0028 16.8 0.1 0.0098 15.0 0.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 GAP87312.1 - 0.04 13.5 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 GAP87312.1 - 0.08 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 ThiF family GIDA PF01134.17 GAP87312.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Glyco_hydro_43 PF04616.9 GAP87313.1 - 2.3e-55 187.7 8.4 3e-55 187.3 5.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF1080 PF06439.6 GAP87313.1 - 0.00071 19.5 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) Glyco_hydro_32N PF00251.15 GAP87313.1 - 0.0063 15.9 1.9 0.0098 15.2 1.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Laminin_G_2 PF02210.19 GAP87313.1 - 0.039 13.9 0.0 0.49 10.4 0.0 2.3 2 0 0 2 2 2 0 Laminin G domain DUF377 PF04041.8 GAP87313.1 - 0.097 11.3 0.2 2.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF377) O-FucT PF10250.4 GAP87314.1 - 1.7e-09 37.2 0.0 5.3e-07 29.0 0.0 2.0 1 1 1 2 2 2 2 GDP-fucose protein O-fucosyltransferase DUF221 PF02714.10 GAP87315.1 - 4.3e-96 321.5 17.8 8.4e-96 320.6 12.3 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 GAP87315.1 - 9.8e-42 142.1 1.2 9.8e-42 142.1 0.8 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 GAP87315.1 - 2e-16 60.2 0.1 3.6e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 GAP87315.1 - 0.004 17.0 0.0 1.4 8.9 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MutS_V PF00488.16 GAP87316.1 - 1.5e-77 260.2 0.0 6.5e-77 258.0 0.0 2.1 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 GAP87316.1 - 4.3e-42 144.2 1.6 9.6e-42 143.0 1.1 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 GAP87316.1 - 3.4e-28 97.9 0.0 8.8e-28 96.6 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 GAP87316.1 - 3.3e-09 36.9 0.1 2.4e-08 34.1 0.0 2.3 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 GAP87316.1 - 5.8e-07 29.6 0.0 1.4e-05 25.1 0.0 2.7 2 0 0 2 2 2 1 MutS family domain IV zf-C2H2_2 PF12756.2 GAP87317.1 - 0.25 11.4 1.4 0.49 10.5 0.0 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) ThiF PF00899.16 GAP87318.1 - 3.7e-39 133.6 0.9 5.5e-39 133.1 0.3 1.5 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 GAP87318.1 - 3.3e-26 90.8 0.0 5.6e-26 90.1 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 GAP87318.1 - 1.4e-25 88.6 0.3 2.4e-25 87.8 0.2 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 GAP87318.1 - 3.9e-13 48.5 2.5 3.9e-13 48.5 1.8 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 GAP87318.1 - 4.4e-05 23.6 0.2 0.00012 22.2 0.1 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UAE_UbL PF14732.1 GAP87318.1 - 0.0095 16.0 0.1 0.26 11.4 0.0 2.7 3 0 0 3 3 3 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain MoeZ_MoeB PF05237.8 GAP87318.1 - 0.011 15.3 0.4 0.022 14.3 0.0 1.7 2 0 0 2 2 2 0 MoeZ/MoeB domain DAO PF01266.19 GAP87318.1 - 0.15 10.9 0.0 0.57 9.0 0.0 1.9 1 1 1 2 2 2 0 FAD dependent oxidoreductase Ecm33 PF12454.3 GAP87318.1 - 0.38 10.6 4.6 0.68 9.8 2.5 1.9 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein Telomere_reg-2 PF10193.4 GAP87319.1 - 5.4e-39 132.9 0.0 1.3e-38 131.7 0.0 1.7 1 0 0 1 1 1 1 Telomere length regulation protein Pkinase PF00069.20 GAP87320.1 - 1.5e-56 191.4 0.0 1.9e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP87320.1 - 2.8e-40 138.0 0.0 4.1e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP87320.1 - 1.9e-05 23.7 0.0 7.3e-05 21.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 GAP87320.1 - 0.027 13.5 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAP87320.1 - 0.045 13.4 0.0 0.74 9.4 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family AAA PF00004.24 GAP87321.1 - 1e-55 187.5 0.0 2e-43 147.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 GAP87321.1 - 1.2e-28 99.0 0.1 2.6e-28 97.9 0.1 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 GAP87321.1 - 2.1e-11 44.1 2.7 1.7e-05 24.9 0.1 3.8 2 1 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.9 GAP87321.1 - 8.9e-09 35.4 0.0 0.00018 21.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) NACHT PF05729.7 GAP87321.1 - 9e-08 31.9 0.5 0.00015 21.4 0.0 3.5 3 0 0 3 3 3 1 NACHT domain AAA_14 PF13173.1 GAP87321.1 - 9e-08 32.0 0.0 0.0012 18.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 GAP87321.1 - 6.2e-07 30.2 0.6 0.056 14.2 0.2 3.1 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAP87321.1 - 1.6e-06 28.3 0.7 0.045 13.8 0.1 3.8 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.1 GAP87321.1 - 1.7e-06 27.9 0.0 0.022 14.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 GAP87321.1 - 4.3e-06 26.5 0.1 0.024 14.3 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 GAP87321.1 - 1.8e-05 25.0 0.1 0.01 16.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 GAP87321.1 - 3e-05 24.1 0.0 0.011 15.7 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.1 GAP87321.1 - 4.5e-05 23.1 0.0 0.18 11.5 0.0 3.1 2 0 0 2 2 2 2 Part of AAA domain Zeta_toxin PF06414.7 GAP87321.1 - 5e-05 22.4 0.0 0.098 11.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin RuvB_N PF05496.7 GAP87321.1 - 6.9e-05 22.0 0.0 0.013 14.5 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 GAP87321.1 - 0.00014 21.5 0.0 0.14 11.6 0.0 2.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 GAP87321.1 - 0.00024 20.5 0.3 0.45 9.9 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 GAP87321.1 - 0.00024 20.5 2.8 1.7 8.0 0.2 3.9 2 2 2 4 4 4 2 AAA domain TIP49 PF06068.8 GAP87321.1 - 0.00036 19.3 0.0 0.58 8.8 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_28 PF13521.1 GAP87321.1 - 0.00037 20.4 0.1 0.14 12.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 GAP87321.1 - 0.00045 19.8 0.0 0.013 15.1 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 GAP87321.1 - 0.00077 19.6 0.0 1.3 9.2 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 GAP87321.1 - 0.0011 18.2 0.1 0.68 9.0 0.0 2.6 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 GAP87321.1 - 0.0068 15.8 0.0 0.42 10.0 0.0 2.6 3 0 0 3 3 2 1 Sigma-54 interaction domain KTI12 PF08433.5 GAP87321.1 - 0.0071 15.5 0.1 0.045 12.9 0.0 2.1 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Cytidylate_kin2 PF13189.1 GAP87321.1 - 0.0087 15.9 0.0 2.1 8.2 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family Arch_ATPase PF01637.13 GAP87321.1 - 0.012 15.3 0.1 1.4 8.5 0.0 3.0 2 1 1 3 3 3 0 Archaeal ATPase SKI PF01202.17 GAP87321.1 - 0.014 15.2 0.1 5.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase KaiC PF06745.8 GAP87321.1 - 0.016 14.3 0.0 4.2 6.4 0.0 2.5 2 0 0 2 2 2 0 KaiC NTPase_1 PF03266.10 GAP87321.1 - 0.021 14.5 0.0 0.46 10.1 0.0 2.4 2 0 0 2 2 2 0 NTPase ABC_tran PF00005.22 GAP87321.1 - 0.031 14.5 0.0 12 6.1 0.0 2.7 2 0 0 2 2 2 0 ABC transporter DUF2075 PF09848.4 GAP87321.1 - 0.033 13.1 0.0 7 5.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 GAP87321.1 - 0.033 13.0 0.2 7 5.4 0.0 2.6 3 0 0 3 3 2 0 NB-ARC domain FtsK_SpoIIIE PF01580.13 GAP87321.1 - 0.041 13.3 0.0 0.33 10.3 0.0 2.3 3 0 0 3 3 2 0 FtsK/SpoIIIE family AAA_3 PF07726.6 GAP87321.1 - 0.043 13.4 0.0 6.7 6.3 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 GAP87321.1 - 0.049 13.1 0.1 0.83 9.1 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 GAP87321.1 - 0.051 12.4 0.0 1 8.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) APS_kinase PF01583.15 GAP87321.1 - 0.065 12.8 0.3 0.28 10.8 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_24 PF13479.1 GAP87321.1 - 0.069 12.7 1.3 6.8 6.2 0.2 2.3 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 GAP87321.1 - 0.1 11.5 0.2 3.4 6.5 0.0 2.5 1 1 1 2 2 2 0 KAP family P-loop domain cobW PF02492.14 GAP87321.1 - 0.16 11.3 1.0 1.9 7.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MCM PF00493.18 GAP87322.1 - 5.8e-135 449.3 0.0 8.6e-135 448.7 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 GAP87322.1 - 3.8e-25 88.7 0.3 1e-24 87.3 0.2 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 GAP87322.1 - 1.2e-07 31.0 0.0 1e-05 24.8 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 GAP87322.1 - 6.5e-06 25.9 0.0 2.3e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 GAP87322.1 - 0.00065 20.0 1.1 0.0023 18.2 0.3 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 GAP87322.1 - 0.016 14.8 0.0 0.064 12.8 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 GAP87322.1 - 0.12 11.8 0.0 0.74 9.2 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain DAP3 PF10236.4 GAP87323.1 - 2.8e-83 279.3 0.0 3.5e-83 279.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 T2SE PF00437.15 GAP87323.1 - 0.048 12.5 0.0 0.072 11.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 GAP87323.1 - 0.12 12.2 0.4 1.9 8.4 0.3 2.6 2 1 0 2 2 2 0 AAA ATPase domain RRS1 PF04939.7 GAP87324.1 - 1e-40 138.9 2.0 1.3e-40 138.5 1.4 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RhoGAP PF00620.22 GAP87325.1 - 6.1e-29 100.5 0.0 1e-28 99.8 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Prenyltrans PF00432.16 GAP87326.1 - 4.7e-58 192.3 8.3 1.6e-12 46.7 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 GAP87326.1 - 1.5e-43 147.7 0.0 1.2e-13 51.4 0.0 4.0 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 GAP87326.1 - 6.7e-11 42.1 0.0 0.0012 18.7 0.0 3.2 1 1 2 3 3 3 3 Prenyltransferase-like RNA_pol_A_bac PF01000.21 GAP87327.1 - 2e-23 82.6 0.0 4.7e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 GAP87327.1 - 1.1e-14 53.3 0.0 1.4e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain FAD_binding_3 PF01494.14 GAP87328.1 - 2.6e-21 76.0 0.2 1.3e-18 67.2 0.1 2.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAP87328.1 - 2e-06 26.9 0.0 0.0058 15.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAP87328.1 - 1.5e-05 24.0 0.3 0.00041 19.3 0.0 2.6 2 1 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAP87328.1 - 5.4e-05 23.0 0.0 0.00011 21.9 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 GAP87328.1 - 0.00012 20.8 0.0 0.047 12.3 0.0 2.8 2 1 1 3 3 3 2 Tryptophan halogenase SE PF08491.5 GAP87328.1 - 0.0033 16.2 0.0 0.005 15.7 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase HI0933_like PF03486.9 GAP87328.1 - 0.0043 15.5 0.0 0.0055 15.2 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 GAP87328.1 - 0.0069 15.5 0.0 0.055 12.5 0.0 2.0 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.1 GAP87328.1 - 0.011 14.7 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 GAP87328.1 - 0.013 15.5 0.0 0.032 14.2 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAP87328.1 - 0.013 15.3 0.0 0.027 14.3 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP87328.1 - 0.066 13.2 0.0 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PsbX PF06596.6 GAP87328.1 - 0.31 10.7 1.4 14 5.4 0.1 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) Pil1 PF13805.1 GAP87329.1 - 1.5e-99 332.5 5.1 2e-99 332.1 3.3 1.3 1 1 0 1 1 1 1 Eisosome component PIL1 DUF2508 PF10704.4 GAP87329.1 - 0.0025 17.9 0.8 0.06 13.5 0.1 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2508) Ribophorin_I PF04597.9 GAP87330.1 - 4.8e-148 493.2 0.6 5.5e-148 493.0 0.4 1.0 1 0 0 1 1 1 1 Ribophorin I HNH_2 PF13391.1 GAP87331.1 - 2.4e-11 43.2 0.0 5.7e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease DUF1929 PF09118.6 GAP87331.1 - 0.16 12.0 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1929) Peptidase_C97 PF05903.9 GAP87332.1 - 2.7e-07 30.5 0.1 6.4e-07 29.2 0.1 1.7 2 0 0 2 2 2 1 PPPDE putative peptidase domain LRAT PF04970.8 GAP87332.1 - 0.0028 17.6 3.0 0.1 12.5 0.3 3.0 2 1 0 3 3 3 1 Lecithin retinol acyltransferase DUF778 PF05608.7 GAP87332.1 - 0.045 13.6 0.1 0.094 12.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF778) Hexokinase_2 PF03727.11 GAP87333.1 - 1.5e-88 296.1 0.0 2e-88 295.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 GAP87333.1 - 3.6e-76 255.0 0.0 1.6e-75 252.9 0.0 1.8 2 0 0 2 2 2 1 Hexokinase Ank_2 PF12796.2 GAP87334.1 - 0.00052 20.3 0.1 0.0017 18.6 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) VTC PF09359.5 GAP87335.1 - 4e-100 334.4 0.0 4e-100 334.4 0.0 1.6 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 GAP87335.1 - 4.3e-29 102.1 6.7 1.3e-14 54.7 1.0 3.0 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 GAP87335.1 - 4.5e-12 46.0 3.1 8.7e-12 45.0 2.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Peptidase_M75 PF09375.5 GAP87335.1 - 0.018 14.3 0.1 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 Imelysin Cys_Met_Meta_PP PF01053.15 GAP87336.1 - 5.8e-24 84.0 0.0 7.9e-24 83.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Complex1_49kDa PF00346.14 GAP87338.1 - 3.1e-134 446.1 0.0 4.1e-134 445.7 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Glyco_hydro_2_N PF02837.13 GAP87339.1 - 4.1e-18 65.5 0.1 1.5e-17 63.6 0.0 2.1 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 GAP87339.1 - 3.4e-15 55.7 0.0 6.9e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 GAP87339.1 - 6.7e-11 42.6 0.0 1.9e-10 41.1 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 MCM PF00493.18 GAP87340.1 - 1.4e-138 461.2 0.1 2.2e-138 460.5 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 GAP87340.1 - 3.7e-25 88.7 0.1 1.3e-24 86.9 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 GAP87340.1 - 1e-05 25.2 0.0 6.1e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 GAP87340.1 - 1.7e-05 24.0 0.0 0.00056 19.1 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 GAP87340.1 - 0.0016 18.0 0.0 0.0063 16.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 GAP87340.1 - 0.1 12.0 0.2 4.2 6.8 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain Clat_adaptor_s PF01217.15 GAP87341.1 - 1.1e-14 54.3 0.7 1.5e-14 53.9 0.5 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AAA_18 PF13238.1 GAP87341.1 - 0.018 15.3 0.1 0.025 14.9 0.1 1.1 1 0 0 1 1 1 0 AAA domain Sua5_yciO_yrdC PF01300.13 GAP87342.1 - 8.3e-57 191.3 0.0 1.2e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 GAP87342.1 - 2.5e-27 95.4 0.0 5.9e-27 94.2 0.0 1.7 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding TroA PF01297.12 GAP87342.1 - 0.086 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Periplasmic solute binding protein family COG4 PF08318.7 GAP87343.1 - 2.9e-98 328.6 0.0 4.4e-98 328.0 0.0 1.3 1 0 0 1 1 1 1 COG4 transport protein THOC7 PF05615.8 GAP87344.1 - 1.1e-33 116.4 2.6 8.7e-33 113.5 0.0 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 DUF2664 PF10867.3 GAP87344.1 - 0.044 14.4 0.7 0.044 14.4 0.5 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2664) FUSC PF04632.7 GAP87344.1 - 0.11 10.9 12.2 0.13 10.6 8.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Atg14 PF10186.4 GAP87344.1 - 4.8 6.0 9.6 3.1 6.6 3.7 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TBCA PF02970.11 GAP87345.1 - 2.7e-19 69.0 3.9 3.4e-19 68.6 2.7 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A CALCOCO1 PF07888.6 GAP87345.1 - 0.0025 16.1 2.8 0.0029 15.9 1.9 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like COG2 PF06148.6 GAP87345.1 - 0.015 15.1 1.8 0.027 14.3 0.2 1.8 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spectrin PF00435.16 GAP87345.1 - 0.017 15.4 1.9 0.021 15.1 0.8 1.5 1 1 1 2 2 2 0 Spectrin repeat Cor1 PF04803.7 GAP87345.1 - 0.04 13.6 0.4 0.049 13.3 0.3 1.3 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region OmpH PF03938.9 GAP87345.1 - 0.05 13.5 3.8 0.073 13.0 2.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Syntaxin PF00804.20 GAP87345.1 - 0.059 13.5 1.5 0.073 13.2 1.0 1.2 1 0 0 1 1 1 0 Syntaxin IncA PF04156.9 GAP87345.1 - 0.067 12.7 2.8 0.088 12.3 2.0 1.1 1 0 0 1 1 1 0 IncA protein ApoLp-III PF07464.6 GAP87345.1 - 0.089 12.8 4.6 0.14 12.2 3.2 1.4 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF1993 PF09351.5 GAP87345.1 - 0.094 12.6 1.4 0.14 12.1 0.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1993) DUF3921 PF13060.1 GAP87345.1 - 0.23 11.3 1.1 1.2 9.1 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3921) Herpes_UL36 PF03586.8 GAP87345.1 - 0.23 10.5 3.9 0.26 10.3 2.0 1.6 1 1 1 2 2 2 0 Herpesvirus UL36 tegument protein CASP_C PF08172.7 GAP87345.1 - 0.64 8.9 3.4 1.7 7.6 0.2 2.0 1 1 1 2 2 2 0 CASP C terminal COX17 PF05051.8 GAP87346.1 - 3.7e-20 71.6 4.6 4.7e-20 71.3 3.2 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) YedD PF13987.1 GAP87346.1 - 0.12 11.9 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 YedD-like protein Cmc1 PF08583.5 GAP87346.1 - 0.17 11.6 2.2 1.6 8.5 0.0 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Sugar_tr PF00083.19 GAP87347.1 - 2.6e-81 273.5 18.8 3e-81 273.3 13.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP87347.1 - 1.3e-33 116.2 53.1 7.4e-32 110.4 17.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAP87347.1 - 1.2e-07 30.3 13.6 1.4e-07 30.1 0.3 2.2 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Complex1_LYR PF05347.10 GAP87348.1 - 9.9e-16 57.2 1.1 2.9e-15 55.7 0.8 1.8 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAP87348.1 - 4.8e-11 42.7 1.2 4.8e-11 42.7 0.9 2.6 3 0 0 3 3 3 1 Complex1_LYR-like Zn_clus PF00172.13 GAP87349.1 - 8.3e-07 28.8 9.8 2.6e-06 27.2 6.8 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SURF4 PF02077.10 GAP87350.1 - 2e-95 319.2 8.0 2.2e-95 319.0 5.5 1.0 1 0 0 1 1 1 1 SURF4 family Peptidase_A24 PF01478.13 GAP87350.1 - 0.29 11.3 15.1 0.24 11.5 0.9 2.7 2 1 0 2 2 2 0 Type IV leader peptidase family Halogen_Hydrol PF10112.4 GAP87350.1 - 0.44 9.9 2.5 3.4 7.0 0.4 2.3 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Wzy_C PF04932.10 GAP87350.1 - 7.4 6.3 10.7 0.35 10.6 2.6 2.0 2 0 0 2 2 2 0 O-Antigen ligase HR_lesion PF05514.6 GAP87350.1 - 7.5 6.3 9.8 0.98 9.2 1.8 2.9 3 1 0 4 4 4 0 HR-like lesion-inducing FAD_binding_4 PF01565.18 GAP87352.1 - 3.5e-22 78.3 0.2 6.2e-22 77.5 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain DUF2454 PF10521.4 GAP87353.1 - 9.8e-57 192.0 0.0 1.8e-56 191.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) Syja_N PF02383.13 GAP87354.1 - 7.3e-89 297.6 0.0 1.6e-88 296.5 0.0 1.6 2 0 0 2 2 2 1 SacI homology domain DUF1077 PF06417.7 GAP87355.1 - 1.6e-55 185.8 2.2 2e-55 185.5 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DUF2360 PF10152.4 GAP87355.1 - 1.1 9.5 3.8 1.9 8.7 2.6 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Adaptin_N PF01602.15 GAP87356.1 - 5.1e-116 388.0 11.6 6.4e-67 226.0 5.7 2.0 1 1 1 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.1 GAP87356.1 - 2.8e-19 69.1 4.8 6e-12 45.6 0.1 4.7 3 2 2 5 5 5 4 HEAT repeats Cnd1 PF12717.2 GAP87356.1 - 8e-19 68.1 1.6 5.6e-18 65.4 0.0 2.9 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 GAP87356.1 - 4.3e-13 48.1 3.7 0.00011 22.0 0.0 4.9 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 GAP87356.1 - 1.5e-06 28.4 5.7 0.066 13.7 0.1 6.0 5 1 1 6 6 6 1 HEAT-like repeat Arm PF00514.18 GAP87356.1 - 4.7e-05 23.0 1.1 0.81 9.6 0.0 5.0 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 GAP87356.1 - 0.00032 20.1 2.0 0.47 9.7 0.2 3.4 3 1 0 3 3 3 2 CLASP N terminal Atx10homo_assoc PF09759.4 GAP87356.1 - 0.0016 18.1 1.1 1.8 8.3 0.0 4.0 4 1 1 5 5 5 1 Spinocerebellar ataxia type 10 protein domain DUF4042 PF13251.1 GAP87356.1 - 0.013 15.0 0.3 2.1 7.8 0.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4042) DUF2435 PF10363.4 GAP87356.1 - 0.049 13.5 1.0 1.2 9.0 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2435) Rad60-SLD_2 PF13881.1 GAP87358.1 - 2.7e-13 49.7 0.1 6.6e-13 48.5 0.1 1.6 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 GAP87358.1 - 0.00024 20.4 0.0 0.00067 18.9 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 GAP87358.1 - 0.0003 20.9 0.0 0.00054 20.0 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Omp28 PF11551.3 GAP87358.1 - 0.014 14.9 0.0 0.02 14.4 0.0 1.3 1 1 0 1 1 1 0 Outer membrane protein Omp28 UMP1 PF05348.6 GAP87359.1 - 1.4e-16 60.6 0.0 1.7e-16 60.3 0.0 1.3 1 1 0 1 1 1 1 Proteasome maturation factor UMP1 DEC-1_N PF04625.8 GAP87359.1 - 2.6 6.6 5.2 3 6.4 3.6 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region ABC_tran PF00005.22 GAP87360.1 - 8.1e-24 84.4 0.0 1.6e-10 41.3 0.0 3.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 GAP87360.1 - 2e-09 37.8 0.6 0.0055 16.7 0.2 3.8 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 GAP87360.1 - 1.3e-06 29.2 0.0 0.085 13.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 GAP87360.1 - 4.2e-05 23.3 0.0 0.14 12.0 0.0 2.4 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 GAP87360.1 - 0.00034 21.0 0.7 0.0084 16.4 0.6 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 GAP87360.1 - 0.00035 20.0 0.1 0.05 13.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 GAP87360.1 - 0.0016 18.5 0.0 1.6 8.8 0.0 3.3 4 0 0 4 4 3 1 AAA domain AAA_33 PF13671.1 GAP87360.1 - 0.0048 16.7 0.0 3 7.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 GAP87360.1 - 0.012 16.0 0.0 0.99 9.9 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein AAA_25 PF13481.1 GAP87360.1 - 0.029 13.7 0.0 2.9 7.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 GAP87360.1 - 0.029 13.8 0.0 9.1 5.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 GAP87360.1 - 0.036 13.5 0.0 3.5 6.9 0.0 2.6 3 0 0 3 3 3 0 AAA-like domain MobB PF03205.9 GAP87360.1 - 0.052 13.2 0.0 13 5.5 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 GAP87360.1 - 0.057 13.6 0.2 0.55 10.4 0.0 2.6 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 GAP87360.1 - 0.061 13.5 0.0 3.3 7.9 0.0 2.6 3 0 0 3 3 2 0 RNA helicase AAA_18 PF13238.1 GAP87360.1 - 0.077 13.3 0.0 12 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 GAP87360.1 - 0.12 10.8 0.1 0.18 10.2 0.1 1.1 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 GAP87360.1 - 0.12 11.8 0.0 6.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 GAP87360.1 - 0.13 12.1 0.0 11 5.9 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_16 PF13191.1 GAP87360.1 - 0.15 12.0 1.3 12 5.7 0.0 2.8 2 2 0 2 2 2 0 AAA ATPase domain CorA PF01544.13 GAP87362.1 - 0.049 12.6 10.1 0.069 12.1 5.6 2.1 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Pkinase PF00069.20 GAP87363.1 - 4.5e-19 68.6 0.0 1.1e-18 67.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP87363.1 - 1.1e-08 34.4 0.0 4.1e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase DHH PF01368.15 GAP87363.1 - 0.025 14.2 0.0 0.16 11.6 0.0 2.2 2 1 0 2 2 2 0 DHH family Pkinase PF00069.20 GAP87364.1 - 7e-21 74.5 0.0 1.5e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP87364.1 - 3.5e-13 49.2 0.0 9.3e-13 47.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAP87364.1 - 0.013 15.2 0.0 3.2 7.4 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1777 PF08648.7 GAP87365.1 - 0.002 17.8 12.2 0.0024 17.6 8.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) RNase_H2-Ydr279 PF09468.5 GAP87365.1 - 0.01 15.0 6.9 0.011 14.9 4.8 1.0 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) PBP_sp32 PF07222.7 GAP87365.1 - 0.013 14.6 8.4 0.014 14.5 5.8 1.0 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CAF-1_p150 PF11600.3 GAP87365.1 - 0.04 13.2 25.1 0.045 13.1 17.4 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC45 PF02724.9 GAP87365.1 - 0.049 11.6 3.5 0.052 11.5 2.5 1.1 1 0 0 1 1 1 0 CDC45-like protein GAGA_bind PF06217.7 GAP87365.1 - 0.066 13.1 4.6 0.07 13.0 3.2 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.12 GAP87365.1 - 0.084 12.6 4.1 0.085 12.6 2.8 1.1 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.7 GAP87365.1 - 0.087 11.4 5.9 0.1 11.2 4.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.7 GAP87365.1 - 0.094 12.5 8.5 0.1 12.4 5.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BSMAP PF12280.3 GAP87365.1 - 0.17 11.7 1.8 0.17 11.7 1.3 1.1 1 0 0 1 1 1 0 Brain specific membrane anchored protein Peptidase_S49_N PF08496.5 GAP87365.1 - 0.2 11.4 8.8 0.23 11.2 6.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4337 PF14235.1 GAP87365.1 - 0.22 11.3 6.1 0.25 11.1 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) AAA_11 PF13086.1 GAP87365.1 - 0.23 11.0 5.6 0.24 10.9 3.9 1.1 1 0 0 1 1 1 0 AAA domain GBP_C PF02841.9 GAP87365.1 - 0.26 10.4 12.9 0.31 10.1 8.9 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF1510 PF07423.6 GAP87365.1 - 0.33 10.2 10.2 0.36 10.1 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 GAP87365.1 - 0.42 8.2 6.3 0.39 8.3 4.4 1.1 1 0 0 1 1 1 0 Ycf1 Pox_Ag35 PF03286.9 GAP87365.1 - 0.64 9.5 11.3 0.75 9.2 7.8 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein YqfQ PF14181.1 GAP87365.1 - 0.67 9.9 10.6 0.88 9.5 7.3 1.2 1 0 0 1 1 1 0 YqfQ-like protein AIF_C PF14721.1 GAP87365.1 - 0.7 10.1 3.1 0.84 9.8 2.2 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term NARP1 PF12569.3 GAP87365.1 - 0.91 8.1 11.7 0.93 8.1 8.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TSA PF03249.8 GAP87365.1 - 0.91 7.9 6.0 1 7.8 4.2 1.0 1 0 0 1 1 1 0 Type specific antigen DUF755 PF05501.6 GAP87365.1 - 0.95 9.5 11.0 1.2 9.1 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Hom_end_hint PF05203.11 GAP87365.1 - 1.3 8.7 6.0 1.6 8.4 4.2 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint DUF3987 PF13148.1 GAP87365.1 - 1.4 7.4 11.4 1.6 7.1 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_23 PF13476.1 GAP87365.1 - 1.9 8.7 11.1 2.2 8.5 7.7 1.1 1 0 0 1 1 1 0 AAA domain DDRGK PF09756.4 GAP87365.1 - 1.9 7.8 24.2 2.6 7.4 16.7 1.2 1 0 0 1 1 1 0 DDRGK domain Sec62 PF03839.11 GAP87365.1 - 2.3 7.5 10.7 2.6 7.3 7.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF2956 PF11169.3 GAP87365.1 - 3.1 7.8 13.9 5.6 6.9 9.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) DUF1682 PF07946.9 GAP87365.1 - 3.6 6.3 24.1 4.9 5.9 16.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) MIP-T3 PF10243.4 GAP87365.1 - 4.6 5.6 24.1 5.6 5.3 16.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Trypan_PARP PF05887.6 GAP87365.1 - 4.6 7.0 8.8 5.8 6.7 6.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Casc1 PF12366.3 GAP87365.1 - 4.9 6.5 9.3 6.1 6.2 6.4 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 DUF1771 PF08590.5 GAP87367.1 - 5.1e-13 48.8 10.5 1.1e-12 47.7 7.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 GAP87367.1 - 7.4e-10 38.8 0.0 2.7e-09 37.0 0.0 2.0 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.19 GAP87367.1 - 1.5e-06 27.7 1.6 0.0073 15.9 0.2 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HBS1_N PF08938.5 GAP87367.1 - 0.018 15.1 0.1 0.051 13.7 0.0 1.8 2 0 0 2 2 2 0 HBS1 N-terminus Cupin_8 PF13621.1 GAP87368.1 - 2.8e-16 59.8 0.1 8.5e-15 54.9 0.1 2.3 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 GAP87368.1 - 2.1e-10 40.8 0.1 5.8e-10 39.4 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.2 GAP87368.1 - 1.3e-08 34.4 0.0 4.1e-08 32.8 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAP87368.1 - 3.7e-05 23.2 0.0 9.2e-05 21.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain DEAD PF00270.24 GAP87369.1 - 5.1e-44 149.7 1.6 7.5e-44 149.1 0.6 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP87369.1 - 1e-27 95.7 0.3 6.2e-27 93.2 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAP87369.1 - 0.0014 18.4 0.0 0.0029 17.4 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 GAP87369.1 - 0.0055 16.3 0.1 0.016 14.8 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 GAP87369.1 - 0.02 15.0 0.1 0.082 13.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 GAP87369.1 - 0.032 13.9 0.1 0.11 12.2 0.1 1.9 1 1 0 1 1 1 0 Part of AAA domain tRNA-synt_1b PF00579.20 GAP87369.1 - 0.06 12.4 0.2 0.29 10.2 0.0 2.1 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) CMS1 PF14617.1 GAP87369.1 - 0.064 12.3 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Fanconi_A PF03511.9 GAP87369.1 - 0.1 12.3 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Fanconi anaemia group A protein Flavi_DEAD PF07652.9 GAP87369.1 - 0.11 12.2 0.1 0.53 10.0 0.1 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain DUF1664 PF07889.7 GAP87370.1 - 0.004 16.9 3.0 1.5 8.5 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) ATG16 PF08614.6 GAP87370.1 - 0.015 15.1 2.2 3.7 7.3 0.2 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 GAP87370.1 - 0.026 13.6 0.6 0.42 9.7 0.1 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein MCPsignal PF00015.16 GAP87370.1 - 0.037 13.5 0.4 5.8 6.3 0.0 2.2 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Ferritin PF00210.19 GAP87370.1 - 0.043 13.5 0.2 0.074 12.8 0.1 1.3 1 0 0 1 1 1 0 Ferritin-like domain Laminin_II PF06009.7 GAP87370.1 - 0.049 13.3 3.2 0.36 10.5 1.7 2.1 1 1 1 2 2 2 0 Laminin Domain II GAS PF13851.1 GAP87370.1 - 0.087 12.0 1.2 8.9 5.4 0.1 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding SNARE PF05739.14 GAP87370.1 - 0.12 12.0 0.2 0.12 12.0 0.2 2.7 3 1 1 4 4 4 0 SNARE domain Myosin_tail_1 PF01576.14 GAP87370.1 - 0.15 9.7 3.8 1.2 6.7 2.3 1.8 1 1 1 2 2 2 0 Myosin tail COG5 PF10392.4 GAP87370.1 - 0.18 11.7 0.8 10 6.0 0.1 2.4 1 1 1 2 2 2 0 Golgi transport complex subunit 5 IncA PF04156.9 GAP87370.1 - 0.22 11.1 3.6 4.3 6.8 0.4 2.1 1 1 0 2 2 2 0 IncA protein Baculo_PEP_C PF04513.7 GAP87370.1 - 0.28 11.0 1.5 2.7 7.8 0.1 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 GAP87370.1 - 0.53 8.8 2.4 0.95 8.0 1.3 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Sec8_exocyst PF04048.9 GAP87370.1 - 0.72 9.4 3.7 12 5.5 0.2 2.7 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain Prefoldin_2 PF01920.15 GAP87370.1 - 0.79 9.5 3.4 20 5.0 0.1 2.7 3 0 0 3 3 3 0 Prefoldin subunit Nsp1_C PF05064.8 GAP87370.1 - 1.5 8.4 3.9 13 5.4 0.4 2.3 2 0 0 2 2 2 0 Nsp1-like C-terminal region Syntaxin PF00804.20 GAP87370.1 - 1.9 8.6 8.6 11 6.2 4.8 2.7 1 1 1 2 2 2 0 Syntaxin Peptidase_S9 PF00326.16 GAP87371.1 - 3.9e-54 183.1 0.0 7.7e-54 182.1 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAP87371.1 - 5.7e-11 42.3 0.0 1.1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 GAP87371.1 - 1e-05 25.0 0.0 5.4e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat NuA4 PF09340.5 GAP87372.1 - 2.5e-25 87.9 0.6 2.5e-25 87.9 0.4 1.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Rhabdo_glycop PF00974.13 GAP87372.1 - 0.074 11.2 0.0 0.088 11.0 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein PWI PF01480.12 GAP87373.1 - 2.1e-29 101.4 0.0 3.6e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 PWI domain Isochorismatase PF00857.15 GAP87374.1 - 2.1e-33 115.6 0.7 2.4e-33 115.5 0.5 1.0 1 0 0 1 1 1 1 Isochorismatase family FAA_hydrolase PF01557.13 GAP87376.1 - 5.3e-50 169.8 0.0 6.9e-50 169.5 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family ZU5 PF00791.15 GAP87376.1 - 0.059 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 ZU5 domain Glyco_hydro_18 PF00704.23 GAP87377.1 - 2e-78 264.2 0.2 5.6e-78 262.7 0.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 M157 PF11624.3 GAP87377.1 - 8.6 5.3 7.2 14 4.7 5.0 1.2 1 0 0 1 1 1 0 MHC class I-like protein M157 GCC2_GCC3 PF07699.8 GAP87379.1 - 0.058 12.9 1.7 0.15 11.6 1.2 1.7 1 0 0 1 1 1 0 GCC2 and GCC3 CHORD PF04968.7 GAP87379.1 - 0.14 12.4 1.0 0.14 12.4 0.7 3.0 2 1 0 2 2 2 0 CHORD Glyco_hydro_61 PF03443.9 GAP87380.1 - 3e-22 79.4 0.0 4.3e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Pyr_redox_3 PF13738.1 GAP87381.1 - 1.3e-05 25.3 0.0 0.0059 16.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP87381.1 - 4.9e-05 23.2 0.0 0.00017 21.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Prenylcys_lyase PF07156.9 GAP87381.1 - 0.00016 20.6 0.0 0.00075 18.4 0.0 1.8 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_9 PF13454.1 GAP87381.1 - 0.00018 21.3 0.3 0.00048 19.9 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 GAP87381.1 - 0.0038 17.1 0.0 0.0038 17.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAP87381.1 - 0.14 10.5 0.2 0.23 9.8 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein PMT PF02366.13 GAP87382.1 - 2.7e-78 262.7 18.9 4.2e-78 262.1 13.1 1.3 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 GAP87382.1 - 3.7e-19 69.0 2.2 6.1e-19 68.3 0.9 1.7 1 1 1 2 2 2 2 MIR domain Fascin PF06268.8 GAP87382.1 - 0.11 12.5 0.1 0.65 10.1 0.0 2.1 2 0 0 2 2 2 0 Fascin domain Glyco_hydro_7 PF00840.15 GAP87383.1 - 2e-121 405.3 21.0 4.3e-120 401.0 14.6 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 GAP87383.1 - 1.6e-13 50.0 11.1 1.6e-13 50.0 7.7 3.9 4 0 0 4 4 4 1 Fungal cellulose binding domain Sporozoite_P67 PF05642.6 GAP87383.1 - 0.3 8.9 2.8 0.4 8.4 2.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glyco_hydro_18 PF00704.23 GAP87384.1 - 6e-22 78.5 0.9 6e-22 78.5 0.6 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 CBM_1 PF00734.13 GAP87384.1 - 5.4e-12 45.1 10.0 3.1e-11 42.7 6.9 2.5 1 0 0 1 1 1 1 Fungal cellulose binding domain Sin_N PF04801.8 GAP87385.1 - 1.3e-19 70.3 0.7 4.7e-19 68.5 0.5 1.8 1 1 0 1 1 1 1 Sin-like protein conserved region DUF572 PF04502.8 GAP87385.1 - 0.33 10.1 5.3 0.47 9.6 3.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) PAT1 PF09770.4 GAP87386.1 - 1.5e-226 754.4 6.6 1.8e-226 754.2 4.6 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 HNH_2 PF13391.1 GAP87387.1 - 1.5e-11 43.8 0.0 2.1e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 HNH endonuclease Glyco_transf_15 PF01793.11 GAP87388.1 - 4.1e-140 466.4 3.6 5.1e-140 466.1 2.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase CDI PF02234.14 GAP87388.1 - 0.013 15.2 0.9 0.041 13.6 0.6 1.8 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor Ribosom_S12_S23 PF00164.20 GAP87389.1 - 1.8e-42 143.6 0.4 2.2e-42 143.3 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Acyl-CoA_dh_1 PF00441.19 GAP87390.1 - 1.1e-40 139.1 5.1 1.6e-40 138.6 3.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAP87390.1 - 3.1e-28 98.6 0.2 1e-27 96.9 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 GAP87390.1 - 5.7e-16 58.9 1.7 9.5e-16 58.2 1.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 GAP87390.1 - 9e-16 57.1 0.0 1.7e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HpaB_N PF11794.3 GAP87390.1 - 0.019 14.3 0.1 0.09 12.1 0.1 2.0 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Glyco_hydro_15 PF00723.16 GAP87391.1 - 2.5e-80 270.2 0.0 3e-80 269.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 GAP87391.1 - 6.9e-18 64.0 0.0 1.9e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 Starch binding domain Zip PF02535.17 GAP87392.1 - 1.9e-59 201.2 8.0 8.8e-49 166.2 1.4 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter SR-25 PF10500.4 GAP87392.1 - 2 7.8 10.6 2.8 7.3 7.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Bul1_C PF04426.7 GAP87393.1 - 2.8e-07 30.0 0.5 5.3e-06 25.8 0.0 2.5 3 0 0 3 3 3 1 Bul1 C terminus Bul1_N PF04425.7 GAP87393.1 - 4.5e-06 25.5 3.9 4.8e-06 25.3 0.5 2.4 2 1 1 3 3 3 2 Bul1 N terminus Arrestin_N PF00339.24 GAP87393.1 - 0.0015 18.3 0.0 0.005 16.6 0.0 2.0 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Transglut_core PF01841.14 GAP87394.1 - 9.5e-12 45.1 0.1 2.9e-11 43.5 0.1 1.8 2 0 0 2 2 2 1 Transglutaminase-like superfamily DUF553 PF04473.7 GAP87394.1 - 0.045 13.0 0.0 0.88 8.8 0.0 2.6 2 1 0 2 2 2 0 Transglutaminase-like domain MFS_1 PF07690.11 GAP87395.1 - 6.7e-40 136.8 64.9 1.4e-39 135.8 42.1 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP87395.1 - 8.2e-10 37.8 37.1 2.5e-09 36.2 7.3 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 GAP87395.1 - 2.4e-06 26.0 25.4 2.4e-06 26.0 17.6 1.9 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 GAP87396.1 - 1.9e-16 59.7 0.0 2.8e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP87396.1 - 6.6e-10 38.7 11.5 1.2e-09 37.9 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIOX_N PF14226.1 GAP87397.1 - 1.8e-24 86.5 0.0 3.2e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAP87397.1 - 1.9e-21 76.1 0.0 4.1e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.17 GAP87398.1 - 1.9e-62 211.3 0.0 2.6e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PITH PF06201.8 GAP87401.1 - 3.4e-41 140.5 0.0 4.6e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 GAP87401.1 - 2.8e-27 94.4 0.0 4e-27 93.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 GAP87401.1 - 2.2e-07 30.8 0.1 8.4e-06 25.8 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 GAP87401.1 - 9.4e-07 29.0 0.1 3.7e-06 27.0 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 GAP87401.1 - 0.00027 20.5 0.1 0.00047 19.7 0.0 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.1 GAP87401.1 - 0.055 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like HyaE PF07449.6 GAP87401.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.16 GAP87401.1 - 0.086 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_9 PF14595.1 GAP87401.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin DnaJ PF00226.26 GAP87402.1 - 2.2e-19 68.9 1.6 3.6e-19 68.2 1.1 1.4 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.8 GAP87402.1 - 0.0024 17.9 0.3 0.0035 17.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Sigma70_ECF PF07638.6 GAP87402.1 - 0.0067 16.1 0.2 4 7.0 0.0 2.3 2 0 0 2 2 2 2 ECF sigma factor Gly-zipper_OmpA PF13436.1 GAP87402.1 - 0.098 12.3 1.7 0.21 11.2 1.2 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF1183 PF06682.7 GAP87402.1 - 7.7 6.0 10.0 0.78 9.2 2.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1183) IDO PF01231.13 GAP87403.1 - 0.52 8.6 2.4 0.9 7.8 1.7 1.3 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase PRA1 PF03208.14 GAP87404.1 - 3.2e-35 120.7 0.9 4.9e-35 120.1 0.7 1.2 1 0 0 1 1 1 1 PRA1 family protein PV-1 PF06637.6 GAP87404.1 - 0.088 11.3 3.0 0.13 10.8 2.1 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DUF3574 PF12098.3 GAP87405.1 - 0.093 12.3 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) MtlR PF05068.7 GAP87406.1 - 0.12 11.7 0.0 0.27 10.6 0.0 1.5 2 0 0 2 2 2 0 Mannitol repressor DUF2306 PF10067.4 GAP87406.1 - 0.14 12.3 3.9 2.6 8.2 0.0 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2306) Pyridoxal_deC PF00282.14 GAP87408.1 - 3e-20 72.0 0.0 6.5e-13 47.8 0.0 3.1 2 1 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 GAP87408.1 - 0.18 10.9 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Glyco_hydro_3 PF00933.16 GAP87409.1 - 7.6e-65 218.8 0.0 1.1e-64 218.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAP87409.1 - 3.8e-45 154.1 0.1 6e-45 153.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain WSC PF01822.14 GAP87409.1 - 3.3e-36 123.0 22.4 3.1e-20 71.8 5.4 2.5 2 0 0 2 2 2 2 WSC domain Fn3-like PF14310.1 GAP87409.1 - 6.6e-07 29.1 0.0 1.7e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 Fibronectin type III-like domain Glyco_hydro_43 PF04616.9 GAP87410.1 - 1.8e-32 112.6 1.9 2.4e-32 112.2 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DinI PF06183.8 GAP87410.1 - 0.11 12.5 0.0 2.4 8.2 0.0 2.2 2 0 0 2 2 2 0 DinI-like family EBP PF05241.7 GAP87411.1 - 9.2e-60 200.9 7.7 1.1e-59 200.7 5.3 1.0 1 0 0 1 1 1 1 Emopamil binding protein Tim17 PF02466.14 GAP87412.1 - 1.6e-25 89.5 4.3 2.1e-25 89.2 2.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2428 PF10350.4 GAP87413.1 - 4e-66 222.6 0.2 1.5e-64 217.5 0.0 2.9 3 0 0 3 3 3 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 GAP87413.1 - 7.7e-06 25.5 11.0 0.5 10.5 0.0 6.9 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.1 GAP87413.1 - 0.00055 20.1 0.5 0.18 12.1 0.2 4.2 4 0 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.1 GAP87413.1 - 0.018 15.5 3.4 1 9.9 0.1 4.4 4 0 0 4 4 4 0 HEAT-like repeat Phosphodiest PF01663.17 GAP87414.1 - 1.5e-16 60.7 2.5 9.5e-12 44.9 0.1 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 GAP87414.1 - 0.00023 20.6 0.0 0.00049 19.5 0.0 1.4 1 1 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 GAP87414.1 - 0.00031 20.0 0.1 0.0031 16.7 0.0 2.3 2 0 0 2 2 2 1 Sulfatase Glyco_transf_22 PF03901.12 GAP87415.1 - 7.6e-59 199.7 26.1 9.3e-59 199.4 18.1 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF4383 PF14325.1 GAP87415.1 - 0.00015 21.7 7.9 0.071 13.1 2.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4383) DUF2346 PF09803.4 GAP87416.1 - 1.8e-05 24.5 2.0 2.5e-05 24.0 1.4 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) Transcrip_reg PF01709.15 GAP87417.1 - 9.1e-53 178.7 0.0 1.1e-52 178.5 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator HEAT_2 PF13646.1 GAP87418.1 - 4.7e-08 33.2 4.0 1.4 9.2 0.3 7.0 6 1 1 7 7 7 3 HEAT repeats HEAT PF02985.17 GAP87418.1 - 1.2e-07 31.1 7.7 2.2 8.5 0.0 8.0 8 0 0 8 8 8 2 HEAT repeat CLASP_N PF12348.3 GAP87418.1 - 0.017 14.4 4.9 1.7 7.9 0.0 4.1 3 0 0 3 3 3 0 CLASP N terminal Vac14_Fab1_bd PF12755.2 GAP87418.1 - 0.081 13.3 0.1 37 4.8 0.0 4.2 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region V-ATPase_H_C PF11698.3 GAP87418.1 - 0.16 11.9 0.1 3.9 7.4 0.0 2.8 2 0 0 2 2 2 0 V-ATPase subunit H Whi5 PF08528.6 GAP87420.1 - 1.2e-08 34.3 0.1 1.9e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Whi5 like Peptidase_M18 PF02127.10 GAP87422.1 - 2.1e-51 174.7 0.0 2.4e-51 174.6 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M18 PF02127.10 GAP87423.1 - 2.7e-107 358.9 0.4 9.7e-106 353.8 0.3 2.0 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 GAP87423.1 - 1.1e-07 30.8 0.2 8.8e-06 24.6 0.0 2.1 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase HTH_3 PF01381.17 GAP87423.1 - 0.099 12.5 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix Xpo1 PF08389.7 GAP87424.1 - 5.1e-32 110.8 0.9 2.5e-30 105.3 0.0 3.3 3 0 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.17 GAP87424.1 - 0.00043 20.1 1.0 5.1 7.4 0.0 4.8 5 0 0 5 5 5 2 HEAT repeat IBN_N PF03810.14 GAP87424.1 - 0.017 15.0 0.1 0.077 12.9 0.0 2.3 2 0 0 2 2 2 0 Importin-beta N-terminal domain PRT_C PF08372.5 GAP87429.1 - 0.13 11.7 2.4 1.5 8.3 0.2 2.4 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal MtrF PF09472.5 GAP87429.1 - 0.36 10.0 0.1 0.36 10.0 0.0 2.9 4 0 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) RPAP1_N PF08621.5 GAP87430.1 - 0.21 11.1 2.5 0.58 9.7 1.7 1.7 1 0 0 1 1 1 0 RPAP1-like, N-terminal ECH PF00378.15 GAP87431.1 - 1.3e-30 106.3 0.0 1.5e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family PP2C PF00481.16 GAP87432.1 - 2.5e-33 115.5 0.0 3.8e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 GAP87432.1 - 2.1e-05 24.0 0.1 8.8e-05 21.9 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 GAP87432.1 - 0.0084 15.8 0.0 1 9.0 0.0 2.8 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) Epimerase PF01370.16 GAP87433.1 - 6.8e-08 32.2 0.3 0.00024 20.6 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 GAP87433.1 - 0.00023 21.4 0.1 0.001 19.3 0.1 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 GAP87433.1 - 0.032 13.1 0.0 0.15 10.9 0.0 1.9 2 0 0 2 2 2 0 Male sterility protein DUF4610 PF15384.1 GAP87433.1 - 0.083 12.4 0.1 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4610) PUF PF00806.14 GAP87434.1 - 7.4e-62 201.4 10.5 2.7e-08 32.8 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat VPEP PF07589.6 GAP87435.1 - 0.88 9.5 4.2 2 8.4 2.9 1.7 1 0 0 1 1 1 0 PEP-CTERM motif DPBB_1 PF03330.13 GAP87436.1 - 2.2e-07 30.7 0.0 6.5e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel adh_short PF00106.20 GAP87437.1 - 9e-22 77.7 0.3 1.2e-21 77.3 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP87437.1 - 8.4e-12 45.3 0.0 1.1e-11 44.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP87437.1 - 4.5e-11 42.7 0.2 6.8e-11 42.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 GAP87437.1 - 0.00037 20.2 0.2 0.023 14.4 0.1 2.5 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Bac_luciferase PF00296.15 GAP87437.1 - 0.01 14.9 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 0 Luciferase-like monooxygenase THF_DHG_CYH_C PF02882.14 GAP87437.1 - 0.062 12.3 0.0 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Phosphodiest PF01663.17 GAP87438.1 - 1.4e-13 50.9 0.3 2.2e-13 50.2 0.2 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 GAP87438.1 - 4.7e-05 22.7 0.1 7.8e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 GAP87438.1 - 4.7e-05 22.8 0.3 8.1e-05 22.1 0.2 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Bac_chlorC PF02043.12 GAP87439.1 - 0.023 14.4 0.0 0.47 10.2 0.0 2.4 2 0 0 2 2 2 0 Bacteriochlorophyll C binding protein ABC_membrane PF00664.18 GAP87440.1 - 4.6e-91 305.0 43.5 1.4e-48 165.7 9.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAP87440.1 - 4e-68 227.9 0.0 8.9e-33 113.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 GAP87440.1 - 2.4e-13 49.8 0.0 6.7e-05 22.2 0.0 3.6 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAP87440.1 - 3.3e-09 37.1 1.0 0.025 14.5 0.1 4.2 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAP87440.1 - 5.4e-09 35.4 1.4 0.00019 20.9 0.2 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 GAP87440.1 - 6.8e-08 31.5 4.9 0.006 15.2 0.0 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 GAP87440.1 - 7.1e-08 32.6 1.5 0.00084 19.3 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 GAP87440.1 - 3.9e-06 27.6 0.0 0.14 13.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 GAP87440.1 - 5.3e-06 25.7 0.1 0.13 11.3 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 GAP87440.1 - 1.7e-05 25.2 0.1 0.044 14.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 GAP87440.1 - 5.7e-05 22.6 2.8 0.3 10.4 0.0 3.7 4 0 0 4 4 4 2 AAA domain SbcCD_C PF13558.1 GAP87440.1 - 0.00019 21.2 1.7 0.37 10.7 0.1 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 GAP87440.1 - 0.00085 19.4 2.8 1.8 8.7 0.1 3.8 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.1 GAP87440.1 - 0.00098 18.7 2.4 3 7.3 0.0 4.0 4 0 0 4 4 4 1 AAA domain DUF87 PF01935.12 GAP87440.1 - 0.0028 17.5 1.2 1.2 8.9 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_33 PF13671.1 GAP87440.1 - 0.003 17.4 0.8 3.9 7.3 0.3 2.9 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.1 GAP87440.1 - 0.0043 17.0 0.2 0.72 9.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAP87440.1 - 0.0059 16.9 0.1 3.7 7.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 GAP87440.1 - 0.0084 15.8 0.2 8.4 6.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 GAP87440.1 - 0.017 14.6 0.1 0.53 9.7 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_19 PF13245.1 GAP87440.1 - 0.018 14.8 1.2 2.2 8.1 0.2 3.1 2 0 0 2 2 2 0 Part of AAA domain AAA_10 PF12846.2 GAP87440.1 - 0.028 13.8 3.4 11 5.3 0.1 3.8 4 0 0 4 4 4 0 AAA-like domain AAA_14 PF13173.1 GAP87440.1 - 0.043 13.7 0.1 5.9 6.8 0.0 3.3 4 0 0 4 4 4 0 AAA domain G-alpha PF00503.15 GAP87440.1 - 0.094 11.3 0.1 12 4.4 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.18 GAP87440.1 - 0.55 10.2 2.9 7.5 6.5 0.1 2.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase DUF1183 PF06682.7 GAP87441.1 - 3.3e-76 256.9 17.6 1e-75 255.3 12.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) BRE1 PF08647.6 GAP87442.1 - 1.3e-21 76.4 8.4 1.3e-21 76.4 5.8 7.0 3 3 4 7 7 6 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 GAP87442.1 - 5.5e-08 32.7 8.9 9.1e-08 32.0 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAP87442.1 - 2.8e-07 30.0 8.0 4.8e-07 29.3 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAP87442.1 - 5.7e-07 29.2 6.0 9.7e-07 28.5 4.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 GAP87442.1 - 1.3e-06 27.9 7.6 2.4e-06 27.1 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAP87442.1 - 4.1e-06 26.4 9.3 7.2e-06 25.6 6.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 GAP87442.1 - 1.2e-05 24.9 4.5 2.8e-05 23.7 3.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 GAP87442.1 - 0.00061 19.5 2.5 0.0012 18.5 1.8 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 GAP87442.1 - 0.0018 17.7 2.0 0.0035 16.8 1.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Spc7 PF08317.6 GAP87442.1 - 0.0022 16.6 10.2 0.0022 16.6 7.1 4.7 2 1 1 4 4 4 1 Spc7 kinetochore protein Reo_sigmaC PF04582.7 GAP87442.1 - 0.0023 17.1 41.8 0.15 11.1 7.2 4.8 1 1 3 5 5 5 3 Reovirus sigma C capsid protein zf-C3HC4_4 PF15227.1 GAP87442.1 - 0.0067 16.2 5.5 0.013 15.4 3.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING bZIP_1 PF00170.16 GAP87442.1 - 0.012 15.5 0.7 0.012 15.5 0.5 8.9 7 1 3 10 10 10 0 bZIP transcription factor zf-RING_4 PF14570.1 GAP87442.1 - 0.022 14.3 7.0 0.11 12.1 5.1 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.6 GAP87442.1 - 0.036 13.8 6.4 0.076 12.8 4.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) HALZ PF02183.13 GAP87442.1 - 0.097 12.4 0.2 0.097 12.4 0.1 8.7 10 1 1 11 11 9 0 Homeobox associated leucine zipper zf-H2C2_2 PF13465.1 GAP87442.1 - 0.13 12.5 2.7 5.9 7.3 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-rbx1 PF12678.2 GAP87442.1 - 0.21 11.6 5.2 0.7 10.0 3.6 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger DUF869 PF05911.6 GAP87442.1 - 0.24 9.6 73.2 0.027 12.7 23.6 3.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) zf-C2H2_6 PF13912.1 GAP87442.1 - 0.24 11.3 1.5 22 5.1 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF904 PF06005.7 GAP87442.1 - 0.27 11.5 0.1 0.27 11.5 0.1 8.8 5 3 2 7 7 7 0 Protein of unknown function (DUF904) FYVE PF01363.16 GAP87442.1 - 0.29 11.0 11.0 3.5 7.6 7.6 2.4 1 1 0 1 1 1 0 FYVE zinc finger zf-FCS PF06467.9 GAP87442.1 - 0.48 10.0 8.6 5.5 6.7 3.0 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2 PF00096.21 GAP87442.1 - 1.1 9.7 5.7 17 5.9 0.1 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type MbeD_MobD PF04899.7 GAP87442.1 - 2 8.3 26.7 0.65 9.9 0.0 7.3 5 3 3 8 8 8 0 MbeD/MobD like Myb_DNA-binding PF00249.26 GAP87443.1 - 1.3e-07 31.4 1.6 1.5e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAP87443.1 - 0.00021 21.3 0.2 0.0011 19.0 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain XPC-binding PF09280.6 GAP87444.1 - 5e-25 86.7 13.5 9.1e-25 85.9 9.4 1.4 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.26 GAP87444.1 - 2e-18 65.6 5.0 3.3e-09 36.3 0.2 2.8 2 1 1 3 3 3 2 UBA/TS-N domain ubiquitin PF00240.18 GAP87444.1 - 8.3e-18 63.5 0.6 1.3e-17 62.9 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 GAP87444.1 - 9.4e-09 34.8 1.1 1.9e-08 33.8 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 GAP87444.1 - 0.00019 21.5 0.0 0.00056 20.0 0.0 1.8 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain UBA_3 PF09288.5 GAP87444.1 - 0.0003 20.3 0.0 0.14 11.7 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain MCM_N PF14551.1 GAP87444.1 - 0.0048 17.3 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Rad60-SLD_2 PF13881.1 GAP87444.1 - 0.0073 16.1 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.11 GAP87444.1 - 0.029 13.8 0.0 0.11 11.9 0.0 2.0 2 0 0 2 2 2 0 CUE domain UBA_2 PF08587.6 GAP87444.1 - 0.099 12.8 0.0 0.49 10.6 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) Rap1_C PF11626.3 GAP87444.1 - 0.11 12.3 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain PrsW-protease PF13367.1 GAP87445.1 - 0.021 13.9 3.9 0.044 12.9 2.7 1.6 1 1 0 1 1 1 0 Protease prsW family ABC2_membrane_3 PF12698.2 GAP87445.1 - 0.25 10.3 3.6 0.33 9.9 2.2 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein Aminotran_3 PF00202.16 GAP87447.1 - 9.4e-99 330.4 0.0 1.1e-98 330.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 GAP87447.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II SRI PF08236.6 GAP87448.1 - 5.9e-23 80.6 9.2 1.6e-22 79.2 6.4 1.8 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.23 GAP87448.1 - 5.3e-22 78.8 0.4 5.3e-22 78.8 0.3 3.2 2 2 0 2 2 2 1 SET domain Med26 PF08711.6 GAP87448.1 - 0.014 14.9 3.1 0.015 14.7 0.1 2.6 3 0 0 3 3 3 0 TFIIS helical bundle-like domain WW PF00397.21 GAP87448.1 - 0.049 13.5 2.1 0.12 12.2 1.5 1.7 1 0 0 1 1 1 0 WW domain AT_hook PF02178.14 GAP87449.1 - 7.6 6.5 10.2 0.12 12.1 1.4 2.5 2 0 0 2 2 2 0 AT hook motif DUF2431 PF10354.4 GAP87450.1 - 2.6e-53 180.3 0.0 3.8e-53 179.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Methyltransf_26 PF13659.1 GAP87450.1 - 0.004 17.1 0.0 0.0073 16.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain SR-25 PF10500.4 GAP87450.1 - 0.11 11.9 18.5 0.22 10.9 12.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.4 GAP87450.1 - 0.28 9.4 2.7 0.29 9.3 1.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Sds3 PF08598.6 GAP87451.1 - 0.01 15.3 0.7 0.01 15.3 0.5 2.0 2 0 0 2 2 2 0 Sds3-like ThiF PF00899.16 GAP87452.1 - 3.1e-14 52.9 0.1 5.3e-14 52.2 0.1 1.3 1 0 0 1 1 1 1 ThiF family eIF-6 PF01912.13 GAP87454.1 - 5.8e-83 276.8 0.9 8.3e-83 276.3 0.7 1.2 1 0 0 1 1 1 1 eIF-6 family DUF342 PF03961.8 GAP87455.1 - 1.4 7.2 4.7 2.1 6.6 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3138 PF11336.3 GAP87455.1 - 3.6 5.6 6.9 0.27 9.3 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) APG6 PF04111.7 GAP87455.1 - 9.1 5.2 12.0 14 4.5 8.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 NDUF_B12 PF08122.7 GAP87456.1 - 2e-17 62.6 0.8 4e-17 61.6 0.5 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family CAF1 PF04857.15 GAP87457.1 - 1.3e-63 214.8 0.2 3.5e-63 213.4 0.0 1.7 2 0 0 2 2 2 1 CAF1 family ribonuclease RFX_DNA_binding PF02257.10 GAP87457.1 - 0.076 13.1 0.0 0.61 10.2 0.0 2.3 2 0 0 2 2 2 0 RFX DNA-binding domain CLTH PF10607.4 GAP87458.1 - 9.6e-30 103.1 0.0 1.9e-29 102.2 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 GAP87458.1 - 0.00013 21.5 0.0 0.00032 20.3 0.0 1.7 1 0 0 1 1 1 1 LisH HLH PF00010.21 GAP87459.1 - 1.2e-13 50.5 0.5 3.3e-13 49.1 0.4 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF16 PF01519.11 GAP87459.1 - 0.034 14.3 1.2 0.059 13.5 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 TFIIA PF03153.8 GAP87459.1 - 0.81 9.5 14.2 1.2 9.0 9.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-5_eIF-2B PF01873.12 GAP87460.1 - 5.5e-41 139.1 0.1 4.2e-40 136.2 0.0 2.1 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.13 GAP87460.1 - 2.8e-25 88.0 1.2 1.3e-24 85.8 0.3 2.5 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon CoaE PF01121.15 GAP87462.1 - 7.1e-43 146.1 0.0 1.4e-42 145.0 0.0 1.5 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.1 GAP87462.1 - 0.015 15.6 0.4 0.092 13.0 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAP87462.1 - 0.016 16.0 0.5 0.067 14.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 GAP87462.1 - 0.033 14.0 0.0 0.088 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain GARS_A PF01071.14 GAP87463.1 - 1.4e-83 279.2 0.0 2.3e-83 278.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 GAP87463.1 - 1.9e-34 118.1 0.0 6.9e-34 116.3 0.0 2.1 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 GAP87463.1 - 1.4e-29 103.0 0.0 8.3e-29 100.5 0.0 2.2 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 GAP87463.1 - 3.3e-27 94.5 0.5 6.7e-27 93.5 0.3 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 GAP87463.1 - 5.5e-17 61.8 2.7 2.2e-16 59.8 1.5 2.4 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 GAP87463.1 - 9.3e-11 41.7 0.0 3.6e-10 39.8 0.0 2.0 2 1 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 GAP87463.1 - 6.5e-09 34.9 0.0 1.5e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 GAP87463.1 - 0.00036 19.9 0.0 0.00082 18.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 GAP87463.1 - 0.0013 18.0 0.0 0.0026 17.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 GAP87463.1 - 0.013 15.3 0.0 0.051 13.4 0.0 2.0 2 1 0 2 2 2 0 ATP-grasp domain RimK PF08443.6 GAP87463.1 - 0.055 12.9 0.1 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Lipase_3 PF01764.20 GAP87464.1 - 2.6e-07 30.3 0.0 6.2e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 GAP87464.1 - 0.011 15.5 0.1 0.031 14.0 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family VPS9 PF02204.13 GAP87465.1 - 8.3e-26 90.0 0.2 1.7e-25 89.0 0.1 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CH PF00307.26 GAP87466.1 - 1.1e-37 128.3 0.0 2.3e-19 69.4 0.0 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 GAP87466.1 - 1.6e-25 88.8 0.0 3.9e-25 87.6 0.0 1.7 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 GAP87466.1 - 2.5e-13 49.4 0.2 1.4e-07 31.0 0.0 3.0 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.1 GAP87466.1 - 0.00024 20.7 0.2 0.0014 18.3 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 GAP87466.1 - 0.00063 19.3 1.2 0.0031 17.1 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 GAP87466.1 - 0.0029 16.7 0.2 0.021 14.1 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 GAP87466.1 - 0.024 14.7 3.7 0.051 13.7 1.4 2.5 2 0 0 2 2 2 0 EF-hand domain pair Spectrin PF00435.16 GAP87466.1 - 0.11 12.8 4.9 4 7.7 0.0 2.7 2 0 0 2 2 2 0 Spectrin repeat FAD-oxidase_C PF02913.14 GAP87468.1 - 8.3e-61 205.4 0.0 1.2e-60 204.9 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 GAP87468.1 - 5.7e-36 123.0 1.2 9.3e-36 122.3 0.6 1.5 2 0 0 2 2 2 1 FAD binding domain Ribosomal_L23 PF00276.15 GAP87469.1 - 3.1e-18 65.5 2.1 6.5e-18 64.4 1.4 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 GAP87469.1 - 2.1e-12 46.8 4.7 2.1e-12 46.8 3.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Phage_lysozyme PF00959.14 GAP87469.1 - 0.011 15.9 0.1 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 Phage lysozyme DUF3321 PF11968.3 GAP87470.1 - 1.7e-86 289.3 0.0 2.2e-86 289.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 GAP87470.1 - 0.029 14.0 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain HAD_2 PF13419.1 GAP87471.1 - 9.5e-32 110.6 0.0 1.1e-31 110.3 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAP87471.1 - 0.0074 15.9 0.0 0.02 14.5 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Acid_PPase PF12689.2 GAP87471.1 - 0.099 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Acid Phosphatase Pkinase PF00069.20 GAP87472.1 - 2.9e-59 200.3 0.0 4.2e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP87472.1 - 6.6e-33 113.8 0.0 9.5e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP87472.1 - 9.4e-13 47.7 0.0 2.8e-10 39.6 0.0 2.4 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 GAP87472.1 - 0.021 13.8 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAN_4 PF14295.1 GAP87473.1 - 1.9e-05 24.2 1.5 4e-05 23.2 1.1 1.6 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 GAP87473.1 - 0.0006 19.5 0.2 0.0017 18.1 0.1 1.7 1 0 0 1 1 1 1 PAN domain SpoIIIAH PF12685.2 GAP87473.1 - 1.3 8.4 3.5 3.6 7.0 2.4 1.7 1 1 0 1 1 1 0 SpoIIIAH-like protein LCM PF04072.9 GAP87474.1 - 1.6e-34 119.0 0.2 2.2e-34 118.6 0.1 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kinetochor_Ybp2 PF08568.5 GAP87475.1 - 7e-88 295.4 0.0 9.2e-88 295.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin HET PF06985.6 GAP87476.1 - 1.2e-25 90.2 0.1 3e-25 88.9 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short_C2 PF13561.1 GAP87477.1 - 1.7e-13 50.8 0.1 1.9e-13 50.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAP87477.1 - 0.0012 18.7 1.4 0.0041 17.0 0.3 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short PF00106.20 GAP87478.1 - 1.3e-15 57.7 0.2 2e-15 57.1 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP87478.1 - 1.6e-13 50.6 0.1 2.5e-13 50.0 0.1 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 GAP87478.1 - 0.074 11.7 0.1 0.091 11.4 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.1 GAP87478.1 - 0.082 12.6 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase YjeF_N PF03853.10 GAP87478.1 - 0.083 12.4 0.1 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 YjeF-related protein N-terminus Cellulase PF00150.13 GAP87480.1 - 5.2e-48 163.6 0.0 7.2e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Man-6-P_recep PF02157.10 GAP87481.1 - 4e-14 52.2 0.0 6.4e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.13 GAP87481.1 - 4.5e-08 32.9 1.0 0.00031 20.5 0.1 2.7 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.5 GAP87481.1 - 1.1e-05 24.8 1.2 1.1e-05 24.8 0.9 3.9 1 1 2 3 3 3 1 Autophagy-related protein 27 SDA1 PF05285.7 GAP87481.1 - 0.91 8.7 20.0 1.3 8.2 13.9 1.1 1 0 0 1 1 1 0 SDA1 DUF2842 PF11003.3 GAP87481.1 - 0.94 9.3 3.4 1.8 8.4 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2842) MRVI1 PF05781.7 GAP87481.1 - 2.4 6.4 4.7 8 4.7 3.2 1.7 1 1 0 1 1 1 0 MRVI1 protein Nop14 PF04147.7 GAP87481.1 - 2.7 5.8 26.4 3.3 5.4 18.3 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 GAP87481.1 - 9.3 4.5 18.9 13 4.0 13.1 1.1 1 0 0 1 1 1 0 Daxx Family Glyco_transf_25 PF01755.12 GAP87482.1 - 7.2e-05 22.5 0.0 0.00076 19.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) SKG6 PF08693.5 GAP87483.1 - 0.00039 19.6 1.5 0.00039 19.6 1.1 2.2 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Rax2 PF12768.2 GAP87483.1 - 0.036 13.2 0.0 0.054 12.6 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity AAA PF00004.24 GAP87484.1 - 6.1e-16 58.8 0.0 9.2e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAP87484.1 - 0.035 14.2 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 GAP87484.1 - 0.13 12.0 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Citrate_synt PF00285.16 GAP87485.1 - 3.1e-114 381.4 0.0 4.2e-114 380.9 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase DUF1771 PF08590.5 GAP87486.1 - 0.014 15.3 1.7 0.014 15.3 1.2 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF1771) PCI_Csn8 PF10075.4 GAP87486.1 - 0.088 12.5 0.3 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 Rep_fac-A_C PF08646.5 GAP87486.1 - 0.41 10.3 3.6 0.87 9.2 0.4 2.9 2 1 2 4 4 4 0 Replication factor-A C terminal domain ArsC PF03960.10 GAP87486.1 - 0.43 10.6 5.4 51 4.0 0.2 3.9 2 1 2 4 4 4 0 ArsC family GlutR_dimer PF00745.15 GAP87486.1 - 5.9 6.8 10.5 0.71 9.8 0.7 3.6 4 0 0 4 4 4 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF883 PF05957.8 GAP87486.1 - 7.4 7.0 16.0 23 5.4 0.3 5.3 3 1 2 6 6 6 0 Bacterial protein of unknown function (DUF883) CHASE3 PF05227.8 GAP87486.1 - 7.6 6.2 11.3 3.1 7.4 1.8 4.0 3 2 0 3 3 3 0 CHASE3 domain GTP_EFTU PF00009.22 GAP87488.1 - 2.6e-21 75.9 0.0 5.3e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 GAP87488.1 - 6e-14 52.0 0.0 1.3e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 GAP87488.1 - 2.2e-09 37.3 1.6 6.2e-09 35.8 0.7 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAP87488.1 - 0.0043 17.0 0.0 0.0093 15.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAP87488.1 - 0.0087 16.5 0.2 0.11 12.9 0.1 2.6 2 1 0 2 2 2 1 Miro-like protein PduV-EutP PF10662.4 GAP87488.1 - 0.01 15.3 0.5 1.3 8.4 0.1 3.2 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D4 PF14578.1 GAP87488.1 - 0.03 13.9 0.2 0.096 12.3 0.1 1.9 1 0 0 1 1 1 0 Elongation factor Tu domain 4 DUF258 PF03193.11 GAP87488.1 - 0.052 12.7 0.1 0.098 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 GAP87488.1 - 0.071 12.9 0.1 0.18 11.5 0.1 1.7 1 0 0 1 1 1 0 Dynamin family p450 PF00067.17 GAP87489.1 - 8.5e-71 238.8 0.0 1e-70 238.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1971 PF09313.6 GAP87489.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) SDH_alpha PF03313.10 GAP87490.1 - 4.2e-91 304.8 1.3 8e-91 303.9 0.9 1.4 1 1 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 GAP87490.1 - 8.6e-52 175.3 0.0 1.7e-51 174.3 0.0 1.5 1 0 0 1 1 1 1 Serine dehydratase beta chain LDB19 PF13002.2 GAP87491.1 - 6e-35 120.4 0.2 1.5e-34 119.1 0.1 1.7 1 1 1 2 2 2 1 Arrestin_N terminal like DUF4606 PF15379.1 GAP87491.1 - 0.0047 16.9 1.8 0.015 15.3 1.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4606) Arrestin_N PF00339.24 GAP87491.1 - 0.012 15.3 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Phage_B PF02304.10 GAP87492.1 - 0.018 15.3 0.0 0.031 14.5 0.0 1.3 1 0 0 1 1 1 0 Scaffold protein B DUF2502 PF10697.4 GAP87492.1 - 0.067 13.2 0.7 0.13 12.3 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2502) SQS_PSY PF00494.14 GAP87494.1 - 1.3e-50 172.1 0.0 1.6e-50 171.8 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase SNF2_N PF00176.18 GAP87495.1 - 2.5e-72 243.2 0.0 3.9e-72 242.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 GAP87495.1 - 3.2e-21 75.2 0.0 6.3e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 GAP87495.1 - 2.2e-12 46.6 0.0 4.9e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 GAP87495.1 - 4.5e-06 26.5 10.3 1.1e-05 25.3 7.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAP87495.1 - 0.00012 21.6 10.5 0.00027 20.5 7.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UBA_4 PF14555.1 GAP87495.1 - 0.00033 20.1 1.0 0.02 14.4 0.0 3.1 4 0 0 4 4 4 1 UBA-like domain zf-RING_2 PF13639.1 GAP87495.1 - 0.0036 17.1 11.0 0.0094 15.7 7.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 GAP87495.1 - 0.0041 16.7 8.6 0.0041 16.7 6.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PLU-1 PF08429.6 GAP87495.1 - 0.0064 15.4 1.5 0.015 14.2 0.3 2.0 2 0 0 2 2 2 1 PLU-1-like protein zf-RING_5 PF14634.1 GAP87495.1 - 0.32 10.7 12.6 0.33 10.7 6.4 2.6 2 1 1 3 3 3 0 zinc-RING finger domain Cytadhesin_P30 PF07271.6 GAP87495.1 - 0.93 8.7 4.7 0.27 10.4 0.1 2.1 2 0 0 2 2 2 0 Cytadhesin P30/P32 Lar_restr_allev PF14354.1 GAP87495.1 - 2.5 8.4 8.7 76 3.7 4.8 2.6 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-C3HC4_4 PF15227.1 GAP87495.1 - 9.2 6.2 8.1 21 5.1 5.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TRAM_LAG1_CLN8 PF03798.11 GAP87496.1 - 3.9e-33 114.6 10.6 4.4e-33 114.5 6.8 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 GAP87496.1 - 2.4e-16 58.9 0.0 6.7e-16 57.5 0.0 1.8 2 0 0 2 2 2 1 TRAM1-like protein MFS_1 PF07690.11 GAP87497.1 - 9.2e-35 119.9 17.6 1.6e-17 63.2 2.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP87497.1 - 5.1e-07 28.6 16.7 6.1e-05 21.7 5.0 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter DUF791 PF05631.9 GAP87497.1 - 3.5e-05 22.6 4.7 4e-05 22.4 1.6 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF791) MFS_2 PF13347.1 GAP87497.1 - 0.00098 17.6 6.3 0.00098 17.6 4.3 2.6 3 0 0 3 3 3 1 MFS/sugar transport protein Folate_carrier PF01770.13 GAP87497.1 - 0.034 12.6 1.0 0.04 12.4 0.0 1.6 2 0 0 2 2 2 0 Reduced folate carrier MFS_3 PF05977.8 GAP87497.1 - 0.054 11.6 10.2 0.33 9.0 1.2 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector OATP PF03137.15 GAP87497.1 - 0.12 10.3 4.8 0.23 9.4 0.1 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.2 GAP87497.1 - 0.17 11.6 6.0 0.45 10.3 0.2 3.8 4 0 0 4 4 4 0 MFS_1 like family Ank_2 PF12796.2 GAP87498.1 - 2.8e-55 184.6 0.3 2.4e-12 46.9 0.0 7.9 6 2 2 8 8 8 6 Ankyrin repeats (3 copies) Ank PF00023.25 GAP87498.1 - 2e-40 134.5 11.2 5.6e-07 29.0 0.0 12.6 11 2 1 12 12 12 8 Ankyrin repeat Ank_3 PF13606.1 GAP87498.1 - 1.2e-34 114.8 3.3 5.7e-06 26.0 0.0 12.4 14 0 0 14 14 14 6 Ankyrin repeat Ank_4 PF13637.1 GAP87498.1 - 1.8e-32 111.0 0.5 0.00016 22.1 0.0 9.7 5 2 5 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP87498.1 - 1.8e-28 97.8 4.7 5e-06 26.5 0.0 7.9 5 1 1 7 7 7 5 Ankyrin repeats (many copies) Pkinase PF00069.20 GAP87498.1 - 7.9e-25 87.4 0.0 1.4e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP87498.1 - 3.7e-18 65.5 0.0 6.1e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 GAP87498.1 - 0.021 13.8 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 GAP87498.1 - 0.036 12.8 0.0 0.054 12.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase SRC-1 PF08832.5 GAP87498.1 - 0.094 13.4 0.4 0.32 11.7 0.1 2.0 2 0 0 2 2 2 0 Steroid receptor coactivator HeLo PF14479.1 GAP87499.1 - 2.1e-14 53.7 0.4 3.8e-14 52.9 0.2 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation P5CR_dimer PF14748.1 GAP87500.1 - 1.2e-38 131.3 0.6 1.2e-38 131.3 0.4 2.2 3 0 0 3 3 3 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 GAP87500.1 - 5.3e-17 62.0 1.8 9.4e-17 61.2 0.3 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 GAP87500.1 - 0.00056 19.6 2.3 0.012 15.3 1.6 2.4 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NMT1_2 PF13379.1 GAP87500.1 - 0.0078 15.6 0.4 0.5 9.7 0.0 2.7 3 1 0 3 3 3 1 NMT1-like family NAD_binding_2 PF03446.10 GAP87500.1 - 0.016 15.0 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PDH PF02153.12 GAP87500.1 - 0.074 11.9 0.0 0.15 10.8 0.0 1.5 1 0 0 1 1 1 0 Prephenate dehydrogenase Shikimate_DH PF01488.15 GAP87500.1 - 0.13 12.3 0.1 0.45 10.6 0.1 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Methyltransf_18 PF12847.2 GAP87501.1 - 0.0024 18.4 0.1 0.0065 17.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP87501.1 - 0.01 16.1 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 GAP87503.1 - 1.2e-17 63.6 17.5 1.8e-17 63.0 12.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily p450 PF00067.17 GAP87504.1 - 1.4e-42 145.8 0.0 2.2e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ComX PF05952.7 GAP87504.1 - 0.029 13.8 0.2 0.14 11.6 0.1 2.1 2 0 0 2 2 2 0 Bacillus competence pheromone ComX Bax1-I PF01027.15 GAP87504.1 - 1.8 8.1 11.4 3.1 7.3 7.9 1.4 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DEAD PF00270.24 GAP87505.1 - 1.9e-35 121.8 0.2 3e-35 121.1 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP87505.1 - 1.5e-20 72.7 0.9 1.8e-10 40.5 0.3 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 GAP87505.1 - 1.2e-06 28.4 0.0 2.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit FAD_binding_3 PF01494.14 GAP87506.1 - 1.1e-10 41.1 0.2 5e-06 25.8 0.0 3.2 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.19 GAP87506.1 - 0.00018 20.5 0.3 0.00069 18.6 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAP87506.1 - 0.0032 17.4 1.6 0.01 15.8 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 GAP87506.1 - 0.0091 14.8 0.0 0.3 9.8 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase Trp_halogenase PF04820.9 GAP87506.1 - 0.063 11.8 0.2 7.1 5.1 0.0 2.9 3 0 0 3 3 3 0 Tryptophan halogenase Anillin PF08174.6 GAP87507.1 - 2.1e-33 115.3 0.2 1e-32 113.1 0.0 2.3 2 0 0 2 2 2 1 Cell division protein anillin PH PF00169.24 GAP87507.1 - 2.3e-08 34.1 0.0 8.1e-08 32.4 0.0 2.0 1 0 0 1 1 1 1 PH domain Na_trans_assoc PF06512.8 GAP87507.1 - 0.65 9.9 29.8 0.43 10.4 7.8 2.7 2 0 0 2 2 2 0 Sodium ion transport-associated IncA PF04156.9 GAP87507.1 - 4.4 6.8 6.9 14 5.1 4.8 1.8 1 0 0 1 1 1 0 IncA protein SSrecog PF03531.9 GAP87508.1 - 3e-72 242.5 0.3 1.8e-71 240.0 0.2 2.0 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 GAP87508.1 - 4.9e-26 90.5 0.1 9.5e-25 86.4 0.0 2.4 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF2201_N PF13203.1 GAP87508.1 - 0.014 14.5 0.0 0.014 14.5 0.0 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain HET PF06985.6 GAP87509.1 - 1.1e-33 116.3 0.0 1.8e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SnoaL PF07366.7 GAP87510.1 - 0.022 14.3 0.0 1.2 8.7 0.0 2.1 1 1 1 2 2 2 0 SnoaL-like polyketide cyclase DUF1900 PF08954.6 GAP87511.1 - 6.8e-49 164.8 0.0 3.2e-48 162.7 0.0 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 GAP87511.1 - 8.8e-35 118.1 0.0 1.5e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 GAP87511.1 - 1.2e-25 88.4 0.5 3e-07 30.0 0.1 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 GAP87511.1 - 0.0021 16.2 0.3 0.087 10.9 0.1 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 GAP87511.1 - 0.011 15.4 0.0 0.035 13.8 0.0 1.7 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A His_biosynth PF00977.16 GAP87512.1 - 1.3e-32 112.9 0.0 1.5e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein DUF4602 PF15375.1 GAP87513.1 - 0.00012 22.1 1.4 0.00012 22.1 0.9 2.9 4 0 0 4 4 4 1 Domain of unknown function (DUF4602) Daxx PF03344.10 GAP87513.1 - 0.031 12.7 7.3 0.039 12.4 5.1 1.1 1 0 0 1 1 1 0 Daxx Family HemY_N PF07219.8 GAP87513.1 - 0.5 9.9 6.4 0.26 10.8 2.5 2.0 2 1 0 2 2 2 0 HemY protein N-terminus Nop14 PF04147.7 GAP87513.1 - 1.3 6.8 8.8 1.8 6.3 6.1 1.3 1 0 0 1 1 1 0 Nop14-like family Glyco_transf_15 PF01793.11 GAP87514.1 - 7.6e-131 435.9 0.0 9.8e-131 435.6 0.0 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF4604 PF15377.1 GAP87516.1 - 5e-14 52.8 0.1 8.1e-14 52.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) GRP PF07172.6 GAP87516.1 - 0.071 13.5 11.7 0.093 13.2 8.1 1.2 1 0 0 1 1 1 0 Glycine rich protein family Chs3p PF12271.3 GAP87517.1 - 1.2e-132 441.3 13.8 1.3e-132 441.1 9.6 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Alginate_exp PF13372.1 GAP87519.1 - 0.024 13.2 0.0 0.029 13.0 0.0 1.1 1 0 0 1 1 1 0 Alginate export RicinB_lectin_2 PF14200.1 GAP87520.1 - 3.3e-10 40.2 0.1 2.8e-05 24.4 0.0 1.9 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.9 GAP87520.1 - 0.016 14.5 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Cytolethal distending toxin A/C family Ricin_B_lectin PF00652.17 GAP87520.1 - 0.023 14.7 0.1 0.044 13.8 0.1 1.5 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain DUF3433 PF11915.3 GAP87522.1 - 1.7e-32 111.4 10.6 7.4e-19 67.7 0.6 3.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) Beta-lactamase PF00144.19 GAP87523.1 - 3e-25 88.9 0.0 1.7e-24 86.4 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 GAP87523.1 - 0.067 12.4 0.0 0.55 9.4 0.0 2.0 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Syndecan PF01034.15 GAP87525.1 - 0.0099 15.5 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 Syndecan domain Alpha_GJ PF03229.8 GAP87525.1 - 0.027 14.8 5.9 0.049 13.9 4.1 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J DUF1191 PF06697.7 GAP87525.1 - 0.078 11.7 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) MGC-24 PF05283.6 GAP87525.1 - 0.091 12.5 11.9 0.017 14.8 5.8 1.5 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Adeno_E3_CR2 PF02439.10 GAP87525.1 - 0.18 11.3 0.2 0.37 10.3 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 tRNA-synt_2d PF01409.15 GAP87526.1 - 7.1e-83 277.5 0.0 1e-82 277.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 GAP87526.1 - 1.7e-08 33.6 0.3 8.2e-05 21.5 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 GAP87526.1 - 0.001 18.7 0.1 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Glyco_hydro_3 PF00933.16 GAP87527.1 - 2.4e-44 151.5 0.0 3.6e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 GAP87527.1 - 1.1e-14 54.1 0.1 2.1e-14 53.2 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3_C PF01915.17 GAP87527.1 - 7.8e-08 32.1 0.0 2.1e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain PA14 PF07691.7 GAP87527.1 - 1.9e-05 24.3 0.0 5.4e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 PA14 domain Abhydrolase_4 PF08386.5 GAP87528.1 - 1.7e-15 56.7 0.0 3.7e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 GAP87528.1 - 8e-11 41.9 0.0 3.5e-10 39.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAP87528.1 - 2.9e-07 30.6 7.5 2.9e-07 30.6 5.2 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP87528.1 - 0.0036 17.0 0.0 0.011 15.4 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3176 PF11374.3 GAP87529.1 - 5e-34 116.5 2.0 1.2e-33 115.2 1.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF3658 PF12395.3 GAP87529.1 - 0.092 12.3 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function FCP1_C PF09309.5 GAP87530.1 - 0.016 14.5 0.2 0.016 14.5 0.1 1.6 2 0 0 2 2 2 0 FCP1, C-terminal Plasmodium_Vir PF05795.6 GAP87530.1 - 0.039 13.1 0.0 0.062 12.5 0.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Ctr PF04145.10 GAP87530.1 - 0.075 13.0 0.2 2.3 8.2 0.0 2.1 2 0 0 2 2 2 0 Ctr copper transporter family PAT1 PF09770.4 GAP87530.1 - 4.6 5.3 12.7 5.9 5.0 8.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1561 PF07598.6 GAP87531.1 - 0.0066 14.4 0.1 0.0092 13.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1561) CDC45 PF02724.9 GAP87531.1 - 0.098 10.6 1.8 0.16 10.0 1.2 1.2 1 0 0 1 1 1 0 CDC45-like protein UQ_con PF00179.21 GAP87532.1 - 1.2e-07 31.3 0.0 2.1e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme adh_short PF00106.20 GAP87533.1 - 6.3e-20 71.7 0.0 9.2e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP87533.1 - 5.4e-06 26.1 0.0 9.1e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 GAP87533.1 - 0.016 14.9 0.7 0.059 13.1 0.3 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 GAP87533.1 - 0.078 12.9 0.1 4.4 7.2 0.1 2.5 1 1 0 1 1 1 0 NADH(P)-binding AA_kinase PF00696.23 GAP87534.1 - 8.8e-35 120.3 0.4 3.3e-34 118.4 0.0 2.0 2 0 0 2 2 2 1 Amino acid kinase family ACT_7 PF13840.1 GAP87534.1 - 3.4e-09 36.0 4.5 3.8e-07 29.5 1.7 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 GAP87534.1 - 1.2e-06 27.7 3.3 2.3e-05 23.7 0.5 2.6 2 0 0 2 2 2 2 ACT domain CN_hydrolase PF00795.17 GAP87535.1 - 2.7e-37 127.9 0.1 3.6e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Cys_Met_Meta_PP PF01053.15 GAP87536.1 - 2e-141 470.8 0.0 2.2e-141 470.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 GAP87536.1 - 1.8e-08 33.8 0.0 1e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 GAP87536.1 - 5.8e-08 31.8 0.1 2.2e-07 29.9 0.0 1.8 1 1 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 GAP87536.1 - 9e-08 31.4 0.0 1.3e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAP87536.1 - 0.00023 20.4 0.7 0.0028 16.8 0.5 2.6 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 GAP87536.1 - 0.00059 18.6 0.0 0.00081 18.1 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.6 GAP87536.1 - 0.002 16.5 0.0 0.0028 16.0 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase SLA_LP_auto_ag PF05889.8 GAP87536.1 - 0.013 14.0 0.0 0.02 13.3 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) CorA PF01544.13 GAP87538.1 - 9.6e-08 31.3 0.2 1.8e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Pkinase PF00069.20 GAP87539.1 - 8.3e-71 238.1 0.0 1e-70 237.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP87539.1 - 8.6e-38 129.8 0.0 1.1e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP87539.1 - 2.1e-08 33.4 0.0 3.6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF605 PF04652.11 GAP87539.1 - 0.42 9.9 15.1 0.58 9.4 10.4 1.2 1 0 0 1 1 1 0 Vta1 like Lectin_leg-like PF03388.8 GAP87540.1 - 5.4e-66 222.0 0.0 6.7e-66 221.6 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family LMBR1 PF04791.11 GAP87541.1 - 3.8e-27 95.0 0.7 6.1e-27 94.3 0.5 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein SOG2 PF10428.4 GAP87542.1 - 5.3 5.5 9.7 7.7 5.0 6.7 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Spiralin PF05215.8 GAP87542.1 - 6.3 5.8 7.7 0.13 11.4 0.5 1.7 2 0 0 2 2 2 0 Spiralin APH PF01636.18 GAP87543.1 - 1.6e-06 28.0 0.0 2.4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAP87543.1 - 7.5e-05 22.3 0.0 0.00017 21.2 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase Amidase02_C PF12123.3 GAP87543.1 - 0.1 12.2 0.2 0.78 9.4 0.3 2.1 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase p450 PF00067.17 GAP87544.1 - 9.6e-60 202.4 0.0 1.4e-59 201.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 GAP87544.1 - 1.1e-24 86.4 2.8 1.8e-24 85.7 1.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP87544.1 - 2e-08 33.9 0.0 4.8e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Lactonase PF10282.4 GAP87545.1 - 6.1e-78 262.3 0.0 7.4e-78 262.0 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller BAR PF03114.13 GAP87546.1 - 8.4e-63 211.9 3.9 1.1e-62 211.5 2.7 1.1 1 0 0 1 1 1 1 BAR domain CP12 PF02672.10 GAP87546.1 - 0.058 13.8 0.0 0.32 11.4 0.0 2.2 2 0 0 2 2 2 0 CP12 domain HisKA_3 PF07730.8 GAP87546.1 - 3 8.2 6.3 4 7.8 0.4 2.8 3 0 0 3 3 3 0 Histidine kinase Vma12 PF11712.3 GAP87546.1 - 3.2 7.4 5.0 1.3e+02 2.2 3.5 2.8 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Pept_tRNA_hydro PF01195.14 GAP87547.1 - 4e-25 88.3 0.0 4.6e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Peptidase_M17_N PF02789.12 GAP87547.1 - 0.14 11.8 0.0 0.44 10.3 0.0 1.7 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain Gluconate_2-dh3 PF13618.1 GAP87548.1 - 2.9 8.0 6.4 6.9 6.8 0.2 2.4 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 p450 PF00067.17 GAP87551.1 - 2.6e-57 194.4 0.0 4.3e-40 137.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Ribosomal_L13 PF00572.13 GAP87552.1 - 1.4e-28 99.5 0.1 2.6e-28 98.6 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L13 DSBA PF01323.15 GAP87552.1 - 0.1 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain BAG PF02179.11 GAP87553.1 - 3.3e-17 62.3 1.1 6.4e-17 61.4 0.7 1.5 1 0 0 1 1 1 1 BAG domain GATA-N PF05349.7 GAP87553.1 - 0.00035 20.7 0.2 0.0009 19.4 0.2 1.7 1 0 0 1 1 1 1 GATA-type transcription activator, N-terminal ubiquitin PF00240.18 GAP87553.1 - 0.0034 16.7 0.0 0.0074 15.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Glutaredoxin PF00462.19 GAP87554.1 - 5.6e-20 71.0 0.0 1e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 GAP87554.1 - 0.025 14.7 0.1 0.073 13.2 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.9 GAP87554.1 - 0.025 14.8 0.0 0.035 14.3 0.0 1.4 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DSBA PF01323.15 GAP87554.1 - 0.049 13.1 0.1 0.18 11.3 0.1 1.8 1 1 0 1 1 1 0 DSBA-like thioredoxin domain Thioredoxin_9 PF14595.1 GAP87554.1 - 0.1 12.1 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin TraF PF13728.1 GAP87554.1 - 0.11 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Chalcone PF02431.10 GAP87555.1 - 2.7e-58 196.6 0.0 3.4e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase DUF505 PF04458.7 GAP87555.1 - 0.097 10.7 0.0 0.14 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF505) FAD_binding_3 PF01494.14 GAP87556.1 - 3.8e-18 65.6 3.5 4.9e-08 32.4 0.2 2.9 2 1 0 2 2 2 2 FAD binding domain SE PF08491.5 GAP87556.1 - 0.0043 15.9 0.0 0.0075 15.1 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.1 GAP87556.1 - 0.0061 16.5 0.1 0.014 15.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_Gly3P_dh_N PF01210.18 GAP87556.1 - 0.01 15.5 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 GAP87556.1 - 0.016 14.5 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 GAP87556.1 - 0.016 13.6 0.0 0.023 13.1 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 GAP87556.1 - 0.023 13.8 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 GAP87556.1 - 0.064 13.1 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAP87556.1 - 0.071 13.5 0.0 0.21 12.0 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP87556.1 - 0.093 12.7 0.0 0.85 9.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 GAP87556.1 - 0.15 11.6 0.0 0.36 10.4 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cyclin_N PF00134.18 GAP87557.1 - 9.4e-05 21.9 0.0 0.00023 20.7 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF3176 PF11374.3 GAP87558.1 - 2.7e-31 107.7 0.6 2.7e-31 107.7 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Pkinase PF00069.20 GAP87559.1 - 5.6e-15 55.1 0.0 7.8e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 GAP87559.1 - 8.8e-08 32.1 0.1 1.2e-07 31.7 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 GAP87559.1 - 1.1e-06 27.9 0.0 1.5e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 GAP87559.1 - 1.1e-05 24.5 0.0 1.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 GAP87559.1 - 0.00015 21.2 0.0 0.00024 20.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 GAP87559.1 - 0.0045 16.5 0.0 0.007 15.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 GAP87559.1 - 0.011 15.1 0.0 0.014 14.7 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL AA_permease PF00324.16 GAP87560.1 - 3.2e-118 395.0 37.3 3.9e-118 394.8 25.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAP87560.1 - 1.3e-31 109.5 39.7 1.7e-31 109.2 27.5 1.1 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.17 GAP87561.1 - 6e-18 64.6 0.0 7.9e-18 64.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1655 PF07868.6 GAP87561.1 - 0.0083 16.0 0.1 0.023 14.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1655) Cytochrom_NNT PF03264.9 GAP87561.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region TPR_12 PF13424.1 GAP87562.1 - 1.1e-11 44.5 0.4 3.1e-07 30.2 0.1 2.4 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAP87562.1 - 2.6e-06 27.6 1.9 0.033 14.5 0.1 3.2 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAP87562.1 - 2.7e-06 26.8 0.9 0.023 14.6 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAP87562.1 - 6e-06 26.0 0.2 0.65 10.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAP87562.1 - 6.8e-06 25.4 1.1 0.02 14.4 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAP87562.1 - 8.3e-06 26.3 0.0 0.00042 20.9 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 GAP87562.1 - 8.7e-06 25.7 0.0 0.08 13.0 0.0 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 GAP87562.1 - 0.00034 20.2 0.5 0.1 12.2 0.0 2.9 2 1 0 2 2 2 1 TPR repeat TPR_4 PF07721.9 GAP87562.1 - 0.00037 20.6 0.0 1.3 9.6 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAP87562.1 - 0.00039 20.7 0.5 9.8 7.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAP87562.1 - 0.00048 20.1 0.2 0.79 10.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAP87562.1 - 0.0069 16.1 0.2 0.5 10.2 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAP87562.1 - 0.0087 15.7 0.3 1 9.2 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Response_reg PF00072.19 GAP87563.1 - 3.8e-16 59.0 0.1 9.8e-16 57.7 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 GAP87563.1 - 7.7e-13 48.1 0.0 1.7e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 GAP87563.1 - 2.2e-08 33.9 0.1 7.5e-08 32.2 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 GAP87563.1 - 0.041 13.5 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_3 PF13492.1 GAP87563.1 - 0.052 13.6 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 GAF domain Fer2 PF00111.22 GAP87564.1 - 5.6e-14 51.6 1.1 6.9e-14 51.3 0.7 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAA_hydrolase_N PF09298.6 GAP87564.1 - 0.0063 16.4 0.1 0.0066 16.4 0.0 1.3 1 1 0 1 1 1 1 Fumarylacetoacetase N-terminal Flagellin_IN PF07196.8 GAP87564.1 - 0.15 12.0 0.1 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Flagellin hook IN motif Rrp15p PF07890.7 GAP87565.1 - 1.3e-30 106.1 8.0 1.3e-30 106.1 5.6 2.0 2 1 0 2 2 2 1 Rrp15p Tox-SHH PF15652.1 GAP87565.1 - 1.4 9.5 4.0 6.4 7.4 0.1 3.0 3 1 0 3 3 3 0 HNH/Endo VII superfamily toxin with a SHH signature TauD PF02668.11 GAP87566.1 - 9.7e-54 182.7 0.0 1.3e-53 182.2 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 GAP87566.1 - 0.00074 18.4 0.0 0.001 18.0 0.0 1.2 1 0 0 1 1 1 1 CsiD DUF971 PF06155.7 GAP87566.1 - 0.1 13.0 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF971) HEAT_EZ PF13513.1 GAP87568.1 - 2.9e-27 94.4 19.1 1.3e-12 47.8 0.0 11.7 10 2 4 14 14 13 4 HEAT-like repeat HEAT_2 PF13646.1 GAP87568.1 - 2.3e-26 91.9 1.4 1.3e-08 35.0 0.0 7.5 3 3 6 9 9 9 4 HEAT repeats HEAT PF02985.17 GAP87568.1 - 2.7e-26 89.2 18.3 2.1e-05 24.1 0.0 10.2 12 0 0 12 12 11 6 HEAT repeat MMS19_C PF12460.3 GAP87568.1 - 6.4e-13 48.2 0.1 0.00043 19.1 0.0 4.6 4 1 0 5 5 5 3 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.2 GAP87568.1 - 1.4e-11 44.6 0.0 0.046 14.1 0.0 6.1 4 3 2 6 6 6 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 GAP87568.1 - 1.9e-11 44.1 0.6 1.6 8.5 0.0 6.9 4 2 3 7 7 7 5 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 GAP87568.1 - 7.5e-07 28.7 1.0 16 4.7 0.0 7.5 6 2 2 8 8 8 0 CLASP N terminal Adaptin_N PF01602.15 GAP87568.1 - 1.1e-06 27.2 0.2 0.004 15.5 0.0 3.1 3 0 0 3 3 3 2 Adaptin N terminal region IBN_N PF03810.14 GAP87568.1 - 0.00021 21.1 3.5 0.0047 16.8 0.1 4.5 4 1 0 4 4 4 1 Importin-beta N-terminal domain Arm PF00514.18 GAP87568.1 - 0.00023 20.8 4.0 23 5.0 0.1 6.6 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Mo25 PF08569.6 GAP87568.1 - 0.087 11.8 1.2 0.38 9.7 0.0 2.5 3 0 0 3 3 3 0 Mo25-like CTD_bind PF04818.8 GAP87569.1 - 3.8e-09 36.6 0.0 9.8e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Exo_endo_phos PF03372.18 GAP87571.1 - 2e-26 93.4 0.9 5.4e-26 92.0 0.6 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4243 PF14027.1 GAP87573.1 - 1.4e-78 264.6 1.2 1.7e-78 264.3 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DUF1910 PF08928.5 GAP87573.1 - 0.063 13.3 0.7 0.15 12.0 0.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1910) USP7_ICP0_bdg PF12436.3 GAP87574.1 - 5.6e-79 264.8 0.0 2.9e-77 259.2 0.0 2.8 2 1 1 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 GAP87574.1 - 1.9e-69 233.3 5.5 2e-68 230.0 2.1 3.1 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 GAP87574.1 - 1.1e-53 182.0 1.6 2e-53 181.2 1.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAP87574.1 - 9.6e-30 104.0 1.1 8.9e-29 100.8 0.0 2.4 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 GAP87574.1 - 5.8e-12 45.9 0.1 2.4e-11 43.9 0.0 2.1 2 0 0 2 2 2 1 MATH domain YukD PF08817.5 GAP87574.1 - 0.035 14.6 0.0 5.6 7.6 0.0 3.3 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukD BCDHK_Adom3 PF10436.4 GAP87575.1 - 6.4e-43 146.1 0.0 9.6e-43 145.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 GAP87575.1 - 5.3e-09 35.7 0.0 4.6e-07 29.5 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 GAP87575.1 - 0.0018 17.9 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Septin PF00735.13 GAP87576.1 - 1.1e-116 388.7 0.3 1.7e-116 388.1 0.2 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 GAP87576.1 - 3.6e-07 30.1 0.0 6.6e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 GAP87576.1 - 5.3e-06 25.6 0.0 1.5e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 GAP87576.1 - 1.4e-05 24.6 2.6 6.9e-05 22.3 0.1 2.5 3 1 0 3 3 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 GAP87576.1 - 0.0014 19.1 0.1 0.0049 17.3 0.1 2.0 1 0 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 GAP87576.1 - 0.0029 17.2 0.1 0.0057 16.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain AIG1 PF04548.11 GAP87576.1 - 0.0033 16.5 0.0 0.0071 15.4 0.0 1.5 1 0 0 1 1 1 1 AIG1 family AAA_22 PF13401.1 GAP87576.1 - 0.0037 17.4 0.4 0.014 15.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain IIGP PF05049.8 GAP87576.1 - 0.0062 15.4 0.0 0.012 14.4 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 GAP87576.1 - 0.012 15.1 1.2 0.016 14.7 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Pox_A32 PF04665.7 GAP87576.1 - 0.012 14.9 0.1 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein Ras PF00071.17 GAP87576.1 - 0.022 14.1 0.7 0.069 12.5 0.5 1.9 2 1 0 2 2 1 0 Ras family T2SE PF00437.15 GAP87576.1 - 0.033 13.0 0.4 0.086 11.7 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.7 GAP87576.1 - 0.041 13.5 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 GAP87576.1 - 0.041 14.1 0.4 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 ABC transporter ArgK PF03308.11 GAP87576.1 - 0.046 12.5 3.1 0.9 8.2 0.0 3.1 3 0 0 3 3 3 0 ArgK protein KAP_NTPase PF07693.9 GAP87576.1 - 0.048 12.6 0.7 0.083 11.8 0.5 1.6 1 1 0 1 1 1 0 KAP family P-loop domain Sigma54_activat PF00158.21 GAP87576.1 - 0.069 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.17 GAP87576.1 - 0.074 13.2 0.0 0.25 11.5 0.0 2.0 2 0 0 2 2 1 0 RNA helicase DUF2968 PF11180.3 GAP87576.1 - 0.077 12.3 7.3 0.2 11.0 5.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) PduV-EutP PF10662.4 GAP87576.1 - 0.077 12.4 0.4 2.9 7.3 0.3 2.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 GAP87576.1 - 0.079 12.9 2.6 0.69 9.8 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain Dynamin_N PF00350.18 GAP87576.1 - 0.14 11.9 8.7 0.84 9.4 0.1 3.1 2 1 1 3 3 3 0 Dynamin family Ribosomal_L6e PF01159.14 GAP87576.1 - 0.3 11.3 6.6 2 8.7 0.1 3.3 3 0 0 3 3 3 0 Ribosomal protein L6e Seryl_tRNA_N PF02403.17 GAP87576.1 - 0.9 9.5 8.1 0.74 9.8 2.6 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Myc-LZ PF02344.10 GAP87576.1 - 6.7 6.4 11.9 1.2 8.8 3.0 2.8 2 1 0 2 2 2 0 Myc leucine zipper domain WD40 PF00400.27 GAP87577.1 - 1e-51 171.0 33.2 1.9e-11 43.3 0.0 12.3 13 0 0 13 13 13 9 WD domain, G-beta repeat Utp12 PF04003.7 GAP87577.1 - 2.8e-26 91.5 0.0 4.2e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 GAP87577.1 - 3e-06 27.0 1.5 0.029 14.0 0.2 5.5 5 2 1 6 6 6 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 GAP87577.1 - 0.00028 18.8 0.0 0.031 12.1 0.0 2.4 2 1 0 2 2 2 2 IKI3 family Nbas_N PF15492.1 GAP87577.1 - 0.022 13.8 0.1 9.9 5.1 0.0 3.2 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Utp13 PF08625.6 GAP87577.1 - 0.037 13.6 0.1 0.085 12.5 0.1 1.6 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain Nup160 PF11715.3 GAP87577.1 - 0.057 11.5 5.5 3.2 5.7 0.0 3.7 2 1 1 4 4 4 0 Nucleoporin Nup120/160 Vps39_2 PF10367.4 GAP87579.1 - 5.4e-08 32.9 0.0 1.3e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 GAP87579.1 - 0.025 14.5 0.0 0.24 11.4 0.0 2.5 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 CASP_C PF08172.7 GAP87580.1 - 7.9e-92 306.7 0.0 7.9e-92 306.7 0.0 2.9 3 1 0 3 3 3 1 CASP C terminal Shugoshin_N PF07558.6 GAP87580.1 - 0.014 15.0 2.8 0.014 15.0 1.9 4.1 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region ATG16 PF08614.6 GAP87580.1 - 0.027 14.3 55.2 0.26 11.0 9.4 5.0 2 1 1 5 5 5 0 Autophagy protein 16 (ATG16) IncA PF04156.9 GAP87580.1 - 0.11 12.0 55.8 0.19 11.2 0.3 5.5 5 1 0 5 5 5 0 IncA protein SlyX PF04102.7 GAP87580.1 - 0.19 12.1 0.0 0.19 12.1 0.0 6.2 6 1 0 6 6 6 0 SlyX NAD_binding_1 PF00175.16 GAP87580.1 - 0.53 10.8 2.1 4.9 7.7 0.0 3.2 2 1 2 4 4 4 0 Oxidoreductase NAD-binding domain Nup54 PF13874.1 GAP87580.1 - 0.94 9.1 26.3 0.62 9.7 2.8 4.6 4 0 0 4 4 4 0 Nucleoporin complex subunit 54 Tropomyosin PF00261.15 GAP87580.1 - 0.94 8.5 48.3 2.3 7.2 0.4 3.7 3 1 0 3 3 3 0 Tropomyosin DUF972 PF06156.8 GAP87580.1 - 3.4 8.0 39.2 5.7 7.3 0.0 6.3 5 2 2 7 7 7 0 Protein of unknown function (DUF972) DUF3455 PF11937.3 GAP87581.1 - 1.9e-45 154.9 0.0 2.7e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Peptidase_C12 PF01088.16 GAP87582.1 - 5.5e-69 231.6 0.0 7.6e-69 231.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Xan_ur_permease PF00860.15 GAP87583.1 - 8.9e-23 80.3 31.3 1.5e-22 79.6 20.0 2.4 2 1 0 2 2 2 1 Permease family SR-25 PF10500.4 GAP87584.1 - 0.67 9.3 16.2 1 8.7 11.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Dicty_CAR PF05462.6 GAP87585.1 - 3.4e-14 52.4 6.7 3.4e-14 52.4 4.7 1.8 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 GAP87585.1 - 4.4e-11 42.3 2.6 4.4e-11 42.3 1.8 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Git3 PF11710.3 GAP87585.1 - 2.2e-06 27.3 8.0 4.1e-06 26.4 5.6 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 GAP87585.1 - 1.5e-05 24.2 1.9 1.9e-05 23.9 1.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 GAP87585.1 - 0.0021 17.2 0.9 0.0035 16.5 0.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Frizzled PF01534.12 GAP87585.1 - 0.026 13.3 6.5 0.12 11.0 0.1 2.3 1 1 1 2 2 2 0 Frizzled/Smoothened family membrane region Glyco_transf_8 PF01501.15 GAP87586.1 - 2.6e-33 115.3 0.0 4.6e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 GAP87586.1 - 0.00043 19.7 0.0 0.00087 18.7 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative Cation_efflux PF01545.16 GAP87587.1 - 1.7e-31 109.3 3.5 2.4e-31 108.8 2.4 1.2 1 0 0 1 1 1 1 Cation efflux family MRP-S33 PF08293.6 GAP87587.1 - 0.14 12.1 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit S27 Glyco_hydro_47 PF01532.15 GAP87588.1 - 1.1e-171 571.4 0.0 1.3e-171 571.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 zf-RING_2 PF13639.1 GAP87589.1 - 1.6e-11 43.8 3.9 2.8e-11 43.0 2.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAP87589.1 - 5e-11 42.5 1.2 9.3e-11 41.6 0.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 GAP87589.1 - 2.7e-06 26.9 1.4 5e-06 26.1 1.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 GAP87589.1 - 4.2e-06 26.3 4.0 2.1e-05 24.1 3.0 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAP87589.1 - 1.3e-05 24.7 2.0 2.3e-05 23.9 1.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAP87589.1 - 1.3e-05 25.0 2.8 4.5e-05 23.3 1.9 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAP87589.1 - 0.00026 20.7 1.1 0.00053 19.7 0.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 GAP87589.1 - 0.00042 19.9 2.4 0.0011 18.6 1.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.1 GAP87589.1 - 0.093 12.2 0.2 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 GAP87589.1 - 0.22 11.4 1.1 0.44 10.4 0.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SnoaL_2 PF12680.2 GAP87590.1 - 0.0054 17.1 0.0 0.0066 16.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Suc_Fer-like PF06999.7 GAP87591.1 - 2.5e-38 132.3 0.0 4.3e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 Sucrase/ferredoxin-like HET PF06985.6 GAP87591.1 - 1.6e-22 80.2 0.0 3.2e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Suc_Fer-like PF06999.7 GAP87592.1 - 7.6e-05 22.8 0.0 8.8e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Glyco_hydro_76 PF03663.9 GAP87593.1 - 2.2e-108 362.9 0.2 2.9e-108 362.5 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 GAP87593.1 - 0.064 12.2 0.2 1.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 FH2 PF02181.18 GAP87594.1 - 9.1e-81 271.5 5.0 9.1e-81 271.5 3.5 1.5 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 GAP87594.1 - 1.7e-65 219.9 0.2 5.4e-65 218.2 0.0 2.1 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 GAP87594.1 - 2.8e-54 183.5 1.1 2.8e-54 183.5 0.7 2.8 2 1 0 2 2 2 1 Diaphanous FH3 Domain Exostosin PF03016.10 GAP87595.1 - 0.0044 16.1 0.2 0.005 15.9 0.1 1.1 1 0 0 1 1 1 1 Exostosin family Sarcoglycan_2 PF05510.8 GAP87595.1 - 0.064 11.5 0.0 0.064 11.5 0.0 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon DUF4131 PF13567.1 GAP87595.1 - 0.11 11.8 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) HDV_ag PF01517.13 GAP87595.1 - 1.1 8.8 7.5 1.1 8.9 4.6 1.3 1 1 0 1 1 1 0 Hepatitis delta virus delta antigen zf-RING_2 PF13639.1 GAP87596.1 - 2.5e-09 36.7 6.9 2.5e-09 36.7 4.8 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 GAP87596.1 - 4.3e-07 29.9 3.9 4.3e-07 29.9 2.7 2.3 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 GAP87596.1 - 4.3e-06 26.2 1.5 4.3e-06 26.2 1.0 2.3 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAP87596.1 - 2.9e-05 23.9 5.9 2.9e-05 23.9 4.1 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAP87596.1 - 3e-05 23.7 2.4 8.9e-05 22.2 1.7 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 GAP87596.1 - 0.0031 17.1 3.9 0.0031 17.1 2.7 2.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAP87596.1 - 0.0095 15.7 4.5 0.0095 15.7 3.1 2.7 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 GAP87596.1 - 0.73 9.6 10.6 0.041 13.5 3.0 2.2 2 0 0 2 2 2 0 zinc-RING finger domain Hus1 PF04005.7 GAP87597.1 - 2.7e-94 315.3 0.0 3.1e-94 315.2 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein DUF2807 PF10988.3 GAP87597.1 - 0.082 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2807) adh_short PF00106.20 GAP87598.1 - 9.7e-18 64.6 0.3 1.3e-17 64.1 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP87598.1 - 8.1e-11 41.9 0.1 1.2e-10 41.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 GAP87598.1 - 0.016 15.2 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 GAP87598.1 - 0.024 14.6 0.2 0.045 13.7 0.1 1.6 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 GAP87598.1 - 0.085 12.2 0.0 0.13 11.7 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAP87598.1 - 0.16 10.8 0.1 0.65 8.8 0.0 1.7 1 1 1 2 2 2 0 Male sterility protein Sec16_C PF12931.2 GAP87602.1 - 2e-91 306.6 0.1 2.8e-91 306.2 0.1 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 GAP87602.1 - 2.7e-26 91.8 0.4 6.6e-26 90.6 0.0 1.9 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region DAO PF01266.19 GAP87603.1 - 2e-35 122.3 0.6 2e-35 122.3 0.4 1.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase PPR_2 PF13041.1 GAP87603.1 - 0.077 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 PPR repeat family Kin17_mid PF10357.4 GAP87604.1 - 2.9e-49 165.9 0.9 2.9e-49 165.9 0.6 2.0 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 GAP87604.1 - 6.4e-05 22.9 0.8 0.00014 21.9 0.6 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAP87604.1 - 0.0077 16.4 0.6 0.016 15.4 0.4 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 GAP87604.1 - 0.025 14.6 0.3 0.025 14.6 0.2 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) PLATZ PF04640.9 GAP87604.1 - 0.11 12.7 0.8 1.2 9.3 0.1 2.6 3 0 0 3 3 3 0 PLATZ transcription factor AA_kinase PF00696.23 GAP87605.1 - 1.4e-35 123.0 0.0 3.2e-35 121.8 0.0 1.6 1 1 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 GAP87605.1 - 1.4e-15 56.3 0.5 5.4e-10 38.5 0.1 2.6 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 GAP87605.1 - 4.5e-14 51.7 4.6 2e-09 36.8 0.2 2.7 2 0 0 2 2 2 2 ACT domain FMN_red PF03358.10 GAP87605.1 - 0.099 12.1 0.0 0.94 8.9 0.0 2.2 2 0 0 2 2 2 0 NADPH-dependent FMN reductase RFX_DNA_binding PF02257.10 GAP87606.1 - 1.3e-29 102.1 0.1 3e-29 100.9 0.1 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain TB2_DP1_HVA22 PF03134.14 GAP87607.1 - 1.5e-31 107.9 7.1 2.3e-31 107.3 4.9 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF4407 PF14362.1 GAP87607.1 - 0.084 11.8 2.0 0.99 8.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Kei1 PF08552.6 GAP87607.1 - 0.48 10.0 6.8 0.75 9.4 3.5 2.0 1 1 1 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 DUF2207 PF09972.4 GAP87607.1 - 0.94 7.9 5.4 1.1 7.7 3.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Bestrophin PF01062.16 GAP87607.1 - 7.6 5.3 12.7 28 3.5 8.8 1.8 1 1 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel IF4E PF01652.13 GAP87608.1 - 1.4e-49 167.7 0.4 2.3e-49 167.0 0.0 1.5 2 0 0 2 2 2 1 Eukaryotic initiation factor 4E CAF1A PF12253.3 GAP87609.1 - 2.2e-21 75.7 2.8 5.6e-21 74.4 2.0 1.7 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 GAP87609.1 - 1 8.6 38.4 6.8 6.0 26.6 2.1 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Borrelia_P83 PF05262.6 GAP87609.1 - 2.8 6.0 27.3 4.2 5.5 18.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein E1-E2_ATPase PF00122.15 GAP87610.1 - 9.6e-66 221.1 4.2 9.6e-66 221.1 2.9 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 GAP87610.1 - 1.2e-32 114.0 0.0 5.2e-31 108.7 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 GAP87610.1 - 1.4e-32 112.7 2.0 1.4e-32 112.7 1.4 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus HAD PF12710.2 GAP87610.1 - 5.7e-16 59.2 0.0 1.2e-15 58.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAP87610.1 - 2.1e-14 52.7 0.2 2.1e-14 52.7 0.1 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 GAP87610.1 - 4.8e-10 39.2 0.0 4.1e-09 36.2 0.0 2.5 2 1 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAP87610.1 - 2.1e-05 24.2 0.1 0.00017 21.2 0.3 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2207 PF09972.4 GAP87610.1 - 0.35 9.3 6.3 0.11 11.0 0.3 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) CoA_binding_3 PF13727.1 GAP87610.1 - 0.42 10.4 6.9 0.45 10.3 1.5 2.7 2 0 0 2 2 2 0 CoA-binding domain Ribosomal_L34 PF00468.12 GAP87611.1 - 2.4e-10 39.9 12.0 4.6e-10 39.0 8.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 Glyco_hydro_3 PF00933.16 GAP87612.1 - 6e-94 314.3 0.0 8.5e-94 313.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAP87612.1 - 3e-58 197.0 0.6 2.6e-57 193.9 0.1 2.6 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAP87612.1 - 5.4e-18 64.6 0.0 1.1e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Lipase_3 PF01764.20 GAP87613.1 - 2.3e-35 121.2 0.0 3.7e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.11 GAP87613.1 - 0.0018 18.0 0.0 0.0055 16.4 0.0 1.9 1 0 0 1 1 1 1 Lipase 3 N-terminal region Abhydrolase_6 PF12697.2 GAP87613.1 - 0.027 14.3 1.7 0.037 13.9 1.2 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Auxin_canalis PF05703.6 GAP87613.1 - 0.038 13.8 1.3 0.064 13.0 0.8 1.4 1 1 0 1 1 1 0 Auxin canalisation Abhydrolase_5 PF12695.2 GAP87613.1 - 0.053 13.2 2.0 0.071 12.8 1.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family FMO-like PF00743.14 GAP87614.1 - 8.2e-24 83.6 0.0 3.6e-14 51.8 0.0 3.3 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 GAP87614.1 - 1.5e-16 61.0 0.0 2.8e-07 30.8 0.0 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAP87614.1 - 2.1e-10 40.5 5.6 1.3e-08 34.7 1.3 4.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 GAP87614.1 - 4.7e-10 38.9 1.0 2.5e-05 23.3 0.3 3.8 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 GAP87614.1 - 5.5e-07 29.5 0.8 2.7e-06 27.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAP87614.1 - 9.8e-07 28.8 0.0 0.068 13.0 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAP87614.1 - 5.5e-05 22.3 0.4 0.0076 15.3 0.1 2.2 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.19 GAP87614.1 - 0.0022 17.1 0.1 0.0042 16.2 0.1 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 GAP87614.1 - 0.0052 17.1 0.1 1.5 9.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAP87614.1 - 0.013 14.4 0.2 0.052 12.4 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 GAP87614.1 - 0.013 13.9 2.5 0.021 13.3 0.3 2.1 3 0 0 3 3 3 0 HI0933-like protein Shikimate_DH PF01488.15 GAP87614.1 - 0.021 14.9 0.0 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DJ-1_PfpI PF01965.19 GAP87614.1 - 0.05 13.0 0.4 0.84 9.0 0.0 2.5 3 0 0 3 3 3 0 DJ-1/PfpI family FAD_binding_2 PF00890.19 GAP87614.1 - 0.065 12.0 0.4 0.37 9.5 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 GAP87614.1 - 0.07 12.1 0.1 0.07 12.1 0.1 2.1 3 0 0 3 3 3 0 FAD binding domain F420_oxidored PF03807.12 GAP87614.1 - 0.16 12.4 0.4 0.41 11.0 0.1 1.9 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent LRR_8 PF13855.1 GAP87615.1 - 7.7e-06 25.5 0.3 0.23 11.2 0.1 4.2 4 1 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 GAP87615.1 - 0.001 18.9 4.0 0.064 13.3 0.0 5.5 7 0 0 7 7 7 1 Leucine Rich repeat LRR_4 PF12799.2 GAP87615.1 - 0.007 15.9 0.3 10 5.9 0.2 4.0 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) FYVE PF01363.16 GAP87615.1 - 0.079 12.8 0.4 0.37 10.7 0.3 2.1 1 1 0 1 1 1 0 FYVE zinc finger Tom37_C PF11801.3 GAP87615.1 - 0.78 9.5 6.1 0.37 10.6 2.4 1.8 2 0 0 2 2 2 0 Tom37 C-terminal domain SpoIIIAH PF12685.2 GAP87615.1 - 1.5 8.2 10.3 1.2 8.5 6.1 1.5 2 0 0 2 2 2 0 SpoIIIAH-like protein SNF2_N PF00176.18 GAP87616.1 - 5.3e-58 196.1 0.1 1.1e-57 195.1 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAP87616.1 - 3e-12 46.2 0.0 6.6e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 GAP87616.1 - 3.1e-05 23.5 12.7 3.1e-05 23.5 8.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAP87616.1 - 0.00055 19.7 12.3 0.00055 19.7 8.5 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAP87616.1 - 0.00078 19.4 11.4 0.00078 19.4 7.9 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAP87616.1 - 0.0012 18.5 10.6 0.0012 18.5 7.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 GAP87616.1 - 0.0015 18.0 0.0 0.0044 16.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-Nse PF11789.3 GAP87616.1 - 0.3 10.6 8.5 0.18 11.3 3.6 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit AT_hook PF02178.14 GAP87616.1 - 1.4 8.8 8.7 0.1 12.3 1.4 2.8 2 0 0 2 2 2 0 AT hook motif tRNA-synt_1g PF09334.6 GAP87617.1 - 3.5e-120 401.2 0.0 7.1e-120 400.2 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 GAP87617.1 - 4.1e-23 81.2 3.4 3.6e-10 38.4 0.0 4.0 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 GAP87617.1 - 4.4e-10 39.1 0.1 0.00032 19.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 GAP87617.1 - 0.004 16.9 0.0 0.009 15.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Peptidase_C28 PF05408.6 GAP87617.1 - 0.045 13.2 0.0 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 Foot-and-mouth virus L-proteinase Acetyltransf_3 PF13302.1 GAP87618.1 - 6.3e-21 75.0 0.0 9.1e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAP87618.1 - 3.1e-10 40.1 0.4 0.00061 19.7 0.0 3.0 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAP87618.1 - 2.1e-06 27.4 0.1 0.024 14.4 0.0 2.4 1 1 1 2 2 2 2 FR47-like protein Acetyltransf_1 PF00583.19 GAP87618.1 - 0.00032 20.6 1.1 0.0058 16.6 0.8 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 GAP87618.1 - 0.0014 18.5 0.1 0.1 12.5 0.0 2.6 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAP87618.1 - 0.087 12.9 0.0 0.38 10.9 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain NTF2 PF02136.15 GAP87619.1 - 0.12 12.7 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain PALP PF00291.20 GAP87620.1 - 2e-51 175.0 0.2 7.2e-51 173.2 0.1 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MgtE_N PF03448.12 GAP87621.1 - 0.26 11.6 2.5 1.7 8.9 0.2 2.6 3 0 0 3 3 3 0 MgtE intracellular N domain Antistasin PF02822.9 GAP87622.1 - 4.8 7.5 10.2 0.52 10.6 0.9 2.6 2 0 0 2 2 2 0 Antistasin family ABC_tran PF00005.22 GAP87623.1 - 1.6e-15 57.6 0.1 1.6e-14 54.3 0.0 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAP87623.1 - 6.6e-11 42.6 0.0 0.00027 21.0 0.2 2.1 1 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 GAP87623.1 - 2.6e-05 23.4 0.0 0.092 11.7 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 GAP87623.1 - 0.0008 18.7 0.0 0.53 9.4 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAP87623.1 - 0.00084 18.8 0.1 0.0016 17.9 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.3 GAP87623.1 - 0.001 16.5 0.2 0.0013 16.1 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) PduV-EutP PF10662.4 GAP87623.1 - 0.0023 17.3 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 GAP87623.1 - 0.0067 17.2 0.3 0.015 16.0 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 GAP87623.1 - 0.012 15.8 0.0 0.035 14.3 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 GAP87623.1 - 0.012 15.8 0.1 0.018 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 GAP87623.1 - 0.016 15.1 0.0 0.047 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 GAP87623.1 - 0.017 15.0 0.2 0.032 14.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 GAP87623.1 - 0.019 14.3 0.1 0.061 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 GAP87623.1 - 0.025 13.8 0.2 0.07 12.3 0.2 1.7 1 1 0 1 1 1 0 ADP-ribosylation factor family SRP54 PF00448.17 GAP87623.1 - 0.034 13.5 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.1 GAP87623.1 - 0.036 14.0 0.7 0.087 12.8 0.5 1.8 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 GAP87623.1 - 0.047 12.8 0.0 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAP87623.1 - 0.049 13.7 0.1 0.21 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 GAP87623.1 - 0.079 12.3 0.0 0.093 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain FtsK_SpoIIIE PF01580.13 GAP87623.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_13 PF13166.1 GAP87623.1 - 0.11 10.9 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 GAP87623.1 - 0.13 11.9 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 NACHT domain Dynamin_N PF00350.18 GAP87623.1 - 0.15 11.9 0.1 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Dynamin family AAA_5 PF07728.9 GAP87623.1 - 0.17 11.5 0.4 0.91 9.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) cobW PF02492.14 GAP87623.1 - 0.2 11.1 0.2 0.31 10.4 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain CENP-I PF07778.6 GAP87624.1 - 1.9e-98 329.9 0.0 2.5e-98 329.5 0.0 1.1 1 0 0 1 1 1 1 Mis6 Acetyltransf_1 PF00583.19 GAP87625.1 - 2e-12 46.9 0.0 3.2e-08 33.4 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAP87625.1 - 3e-06 27.3 0.0 1.2e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAP87625.1 - 0.003 17.3 0.0 0.049 13.4 0.0 2.6 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAP87625.1 - 0.0045 17.1 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAP87625.1 - 0.059 13.5 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF3384 PF11864.3 GAP87627.1 - 3.8e-84 282.8 0.0 7.7e-84 281.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 GAP87627.1 - 2.6e-55 186.7 0.0 5.1e-55 185.7 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 GAP87627.1 - 5.4e-30 104.6 0.0 9.9e-27 93.9 0.0 2.5 2 0 0 2 2 2 2 Tuberin E2 PF08199.6 GAP87627.1 - 7.2 6.2 6.0 0.43 10.1 0.1 2.0 2 0 0 2 2 2 0 Bacteriophage E2-like protein CAS_CSE1 PF03378.10 GAP87628.1 - 1.5e-158 527.6 0.0 3.5e-158 526.4 0.0 1.6 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 GAP87628.1 - 8.7e-152 504.9 1.1 1.3e-151 504.3 0.8 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 GAP87628.1 - 3.6e-12 46.0 0.0 9.3e-12 44.6 0.0 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 GAP87628.1 - 0.044 13.6 4.1 0.87 9.4 0.0 4.3 4 1 0 5 5 5 0 Exportin 1-like protein V-ATPase_H_N PF03224.9 GAP87628.1 - 0.053 12.6 0.3 0.22 10.5 0.0 2.2 2 1 0 2 2 2 0 V-ATPase subunit H Es2 PF09751.4 GAP87629.1 - 5.7e-88 296.1 0.0 3.6e-87 293.4 0.0 1.9 1 1 0 1 1 1 1 Nuclear protein Es2 Sigma70_ner PF04546.8 GAP87629.1 - 0.47 10.0 2.5 0.99 8.9 1.5 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region FMN_red PF03358.10 GAP87630.1 - 7.9e-23 80.6 0.1 1.2e-22 80.0 0.1 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 GAP87630.1 - 0.00037 20.0 0.0 0.0005 19.6 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold EF-hand_1 PF00036.27 GAP87631.1 - 1.5e-24 83.3 14.1 1.7e-06 26.8 0.8 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 GAP87631.1 - 3.6e-23 81.4 4.6 5.1e-12 45.7 0.8 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 GAP87631.1 - 8.4e-19 65.7 7.6 8.2e-05 22.1 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 GAP87631.1 - 5.8e-17 60.1 14.9 2.3e-06 26.6 0.4 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 GAP87631.1 - 2.7e-14 52.4 13.0 2.8e-05 23.6 1.2 4.5 1 1 3 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 GAP87631.1 - 2.3e-07 30.8 0.1 0.00094 19.1 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 GAP87631.1 - 1.6e-05 24.5 8.2 0.015 15.0 0.5 3.7 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 GAP87631.1 - 0.015 15.2 0.2 0.45 10.4 0.1 2.9 2 1 1 3 3 3 0 EF-hand domain EPL1 PF10513.4 GAP87632.1 - 2e-28 99.6 3.5 2e-28 99.6 2.4 2.6 2 1 0 2 2 2 1 Enhancer of polycomb-like PNK3P PF08645.6 GAP87632.1 - 0.032 13.6 0.3 0.061 12.7 0.2 1.4 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase Peptidase_M22 PF00814.20 GAP87633.1 - 5.1e-79 265.5 0.1 6.1e-79 265.2 0.1 1.0 1 0 0 1 1 1 1 Glycoprotease family AMPKBI PF04739.10 GAP87634.1 - 5.4e-28 96.8 1.8 1.8e-27 95.1 0.1 2.5 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain Pkinase PF00069.20 GAP87636.1 - 1.8e-61 207.5 0.0 2.2e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP87636.1 - 5.8e-28 97.6 0.0 7.7e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP87636.1 - 0.057 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like UCH PF00443.24 GAP87637.1 - 1.1e-24 86.9 0.0 1.6e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 GAP87637.1 - 3.3e-11 43.1 0.1 6.7e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 GAP87637.1 - 0.024 14.0 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase EF1G PF00647.14 GAP87638.1 - 1.9e-37 127.2 0.0 3.2e-37 126.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 GAP87638.1 - 8.3e-13 48.1 0.3 2.9e-12 46.4 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAP87638.1 - 2.7e-09 36.8 0.0 2.3e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAP87638.1 - 2.6e-08 33.9 0.0 7.9e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAP87638.1 - 3.9e-08 33.4 0.0 1e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAP87638.1 - 0.00019 21.8 0.1 0.00042 20.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAP87638.1 - 0.001 19.0 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain TPR_11 PF13414.1 GAP87638.1 - 0.057 13.0 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 TPR repeat Chorion_3 PF05387.6 GAP87638.1 - 1 8.7 5.0 1.5 8.1 3.4 1.2 1 0 0 1 1 1 0 Chorion family 3 Ribosomal_S9 PF00380.14 GAP87639.1 - 7.4e-36 123.0 0.1 1.5e-35 122.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 TMEM171 PF15471.1 GAP87640.1 - 2 7.1 5.4 2.8 6.6 3.8 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 DUF2235 PF09994.4 GAP87641.1 - 1.5e-42 145.8 0.0 2.5e-42 145.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Miro PF08477.8 GAP87641.1 - 2.7e-06 27.8 0.1 8.1e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 GAP87641.1 - 9.1e-06 25.6 0.0 2.3e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 GAP87641.1 - 0.00022 20.4 0.0 0.00041 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 GAP87641.1 - 0.0048 15.9 0.1 0.014 14.4 0.0 1.7 2 0 0 2 2 2 1 Septin AAA_17 PF13207.1 GAP87641.1 - 0.01 16.6 0.2 0.031 15.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 GAP87641.1 - 0.019 14.6 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 GAP87641.1 - 0.047 13.6 0.3 0.17 11.8 0.2 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 GAP87641.1 - 0.07 13.2 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 GAP87641.1 - 0.075 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 NTPase FtsK_SpoIIIE PF01580.13 GAP87641.1 - 0.086 12.2 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family HycH PF07450.6 GAP87641.1 - 0.099 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH ABC_tran PF00005.22 GAP87641.1 - 0.15 12.3 0.0 0.82 9.9 0.0 2.2 2 0 0 2 2 2 0 ABC transporter NB-ARC PF00931.17 GAP87641.1 - 0.18 10.6 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Chitin_bind_3 PF03067.10 GAP87642.1 - 0.00018 21.8 0.0 0.00028 21.2 0.0 1.3 1 0 0 1 1 1 1 Chitin binding domain Serglycin PF04360.7 GAP87642.1 - 4.2 7.0 49.0 0.073 12.7 4.2 3.5 2 1 1 3 3 3 0 Serglycin FAT PF02259.18 GAP87643.1 - 2.5e-74 250.3 5.4 5.3e-74 249.3 3.8 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 GAP87643.1 - 3.9e-24 85.4 0.1 1.8e-23 83.2 0.0 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 GAP87643.1 - 1e-09 37.6 0.2 2.9e-09 36.1 0.1 1.9 1 0 0 1 1 1 1 FATC domain TPR_11 PF13414.1 GAP87643.1 - 0.019 14.6 5.8 6.6 6.4 0.4 3.9 3 0 0 3 3 3 0 TPR repeat TPR_2 PF07719.12 GAP87643.1 - 0.12 12.2 2.8 8.2 6.6 0.1 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat tRNA-synt_1 PF00133.17 GAP87644.1 - 4.3e-214 711.9 0.0 2e-213 709.7 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 GAP87644.1 - 1.4e-31 109.3 0.0 3.2e-31 108.1 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 GAP87644.1 - 1.6e-15 56.7 0.5 0.00028 19.6 0.0 4.7 3 2 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 GAP87644.1 - 6.6e-10 38.5 0.0 1.9e-07 30.5 0.0 2.4 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 GAP87644.1 - 0.016 14.3 0.2 0.039 13.0 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain NAD_binding_2 PF03446.10 GAP87645.1 - 2.4e-33 115.2 0.0 3.4e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 GAP87645.1 - 5.3e-14 52.3 0.1 9.9e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 GAP87645.1 - 1.7e-06 28.3 0.0 3.3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF2312 PF10073.4 GAP87645.1 - 0.11 11.8 0.0 7.3 6.0 0.0 2.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Abhydrolase_6 PF12697.2 GAP87646.1 - 7.7e-31 107.7 0.4 1e-30 107.2 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP87646.1 - 3.6e-17 62.7 0.1 1.4e-11 44.4 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP87646.1 - 1.3e-12 47.6 0.0 2.7e-12 46.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAP87646.1 - 1.3e-06 28.1 0.1 2.4e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 GAP87646.1 - 0.0019 18.4 0.0 0.0026 18.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 GAP87646.1 - 0.0068 16.2 0.1 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 GAP87646.1 - 0.05 13.0 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Chlorophyllase PF07224.6 GAP87646.1 - 0.075 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_2 PF02230.11 GAP87646.1 - 0.16 11.3 0.0 7.7 5.8 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Ras PF00071.17 GAP87647.1 - 6.5e-13 48.3 0.0 7.5e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Ras family ESX-1_EspG PF14011.1 GAP87647.1 - 0.12 11.6 0.5 0.14 11.3 0.4 1.0 1 0 0 1 1 1 0 EspG family Ribosomal_S3Ae PF01015.13 GAP87648.1 - 1.5e-82 275.6 3.7 1.9e-82 275.3 2.5 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family mRNA_cap_C PF03919.10 GAP87648.1 - 0.072 13.4 0.2 0.24 11.7 0.0 2.0 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain DUF2877 PF11392.3 GAP87648.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2877) GTP_CH_N PF12471.3 GAP87650.1 - 2.6e-90 301.2 0.0 3.6e-90 300.8 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 GAP87650.1 - 6.4e-16 58.0 0.0 1e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF1996 PF09362.5 GAP87651.1 - 9.8e-80 267.5 2.5 1.2e-79 267.3 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Elf1 PF05129.8 GAP87652.1 - 5.8e-29 99.6 0.8 7.3e-29 99.3 0.6 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like SCA7 PF08313.7 GAP87652.1 - 0.077 12.6 2.1 0.14 11.7 1.4 1.5 1 1 0 1 1 1 0 SCA7, zinc-binding domain zf-BED PF02892.10 GAP87652.1 - 0.22 11.2 2.5 1.1 9.1 0.1 2.2 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.5 GAP87652.1 - 0.4 10.6 2.3 1.4 8.9 1.6 1.9 1 1 0 1 1 1 0 Zinc ribbon domain Gin PF10764.4 GAP87652.1 - 0.62 9.8 3.4 4.6 7.0 0.5 2.4 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin UPRTase PF14681.1 GAP87653.1 - 5.2e-76 254.4 0.0 7.1e-76 254.0 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 GAP87653.1 - 0.00012 21.7 0.0 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 GAP87653.1 - 0.099 12.3 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) WAPL PF07814.8 GAP87655.1 - 7.5e-15 54.5 2.2 7.7e-14 51.1 1.5 2.1 1 1 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Ras PF00071.17 GAP87656.1 - 7.4e-45 152.2 0.1 8.4e-45 152.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAP87656.1 - 1.7e-14 54.3 0.1 2.3e-14 53.9 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAP87656.1 - 8.9e-07 28.3 0.0 1.1e-06 28.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAP87656.1 - 1.5e-06 27.7 0.0 1e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAP87656.1 - 1.5e-05 24.9 0.0 2.4e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 GAP87656.1 - 0.00045 19.4 0.0 0.0012 18.1 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 GAP87656.1 - 0.004 16.4 0.0 0.78 9.0 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA_14 PF13173.1 GAP87656.1 - 0.0065 16.3 0.0 0.008 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 GAP87656.1 - 0.14 12.1 0.0 0.62 10.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Peptidase_C78 PF07910.8 GAP87657.1 - 9.9e-61 204.6 0.0 2.7e-60 203.2 0.0 1.7 1 1 0 1 1 1 1 Peptidase family C78 zf-RAG1 PF10426.4 GAP87657.1 - 0.05 13.5 1.1 0.12 12.3 0.8 1.7 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain AvrE PF11725.3 GAP87657.1 - 0.12 9.3 0.0 0.15 9.0 0.0 1.0 1 0 0 1 1 1 0 Pathogenicity factor zf-Di19 PF05605.7 GAP87657.1 - 0.15 12.2 0.7 0.36 10.9 0.2 1.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Ham1p_like PF01725.11 GAP87658.1 - 4.6e-49 166.3 0.0 5.2e-49 166.1 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AAA_18 PF13238.1 GAP87659.1 - 1.6e-28 99.5 0.6 4.6e-28 98.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAP87659.1 - 3.3e-16 60.1 1.5 1.2e-15 58.3 1.0 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 GAP87659.1 - 1.8e-06 28.1 0.1 0.00012 22.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 GAP87659.1 - 3e-06 27.3 1.0 5e-06 26.5 0.4 1.8 1 1 0 1 1 1 1 AAA domain ADK PF00406.17 GAP87659.1 - 1.1e-05 25.3 0.1 0.0019 18.1 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase AAA_33 PF13671.1 GAP87659.1 - 2.3e-05 24.3 0.2 0.00015 21.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 GAP87659.1 - 5.6e-05 23.0 0.0 0.0001 22.2 0.0 1.4 1 1 0 1 1 1 1 Shikimate kinase AAA_19 PF13245.1 GAP87659.1 - 0.00053 19.6 0.2 0.001 18.8 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain Thymidylate_kin PF02223.12 GAP87659.1 - 0.00084 18.7 0.2 0.27 10.6 0.1 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_16 PF13191.1 GAP87659.1 - 0.001 19.1 0.0 0.0014 18.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAP87659.1 - 0.0022 18.1 0.2 0.003 17.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 GAP87659.1 - 0.0023 17.8 0.0 0.0035 17.2 0.0 1.7 1 1 0 1 1 1 1 Cytidylate kinase-like family NTPase_1 PF03266.10 GAP87659.1 - 0.0036 17.0 0.1 0.0076 15.9 0.1 1.6 1 0 0 1 1 1 1 NTPase KTI12 PF08433.5 GAP87659.1 - 0.0043 16.2 0.1 0.012 14.8 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 MobB PF03205.9 GAP87659.1 - 0.0092 15.6 0.2 0.021 14.5 0.0 1.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.4 GAP87659.1 - 0.012 14.2 0.0 0.024 13.2 0.0 1.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.12 GAP87659.1 - 0.019 14.5 0.5 0.035 13.6 0.1 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.12 GAP87659.1 - 0.024 14.0 0.0 0.044 13.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 GAP87659.1 - 0.026 14.0 0.1 0.052 13.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SE PF00437.15 GAP87659.1 - 0.029 13.2 0.1 0.053 12.4 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Viral_helicase1 PF01443.13 GAP87659.1 - 0.033 13.7 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 GAP87659.1 - 0.046 13.9 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 GAP87659.1 - 0.046 12.7 0.2 0.13 11.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 GAP87659.1 - 0.051 13.0 0.1 0.07 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain AAA_5 PF07728.9 GAP87659.1 - 0.053 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 GAP87659.1 - 0.065 12.8 1.1 0.15 11.5 0.1 2.1 2 1 1 3 3 3 0 AAA domain AAA_24 PF13479.1 GAP87659.1 - 0.078 12.5 0.3 0.21 11.1 0.0 1.8 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.17 GAP87659.1 - 0.087 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ArgK PF03308.11 GAP87659.1 - 0.1 11.3 0.1 0.19 10.4 0.1 1.4 1 0 0 1 1 1 0 ArgK protein Myosin_head PF00063.16 GAP87660.1 - 4.5e-241 801.6 0.0 4.5e-241 801.6 0.0 1.6 2 0 0 2 2 1 1 Myosin head (motor domain) DIL PF01843.14 GAP87660.1 - 6.2e-35 119.2 3.6 2.5e-34 117.2 2.5 2.2 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 GAP87660.1 - 2.1e-08 33.0 37.1 0.00024 20.4 0.4 7.0 7 0 0 7 7 6 4 IQ calmodulin-binding motif AAA_22 PF13401.1 GAP87660.1 - 0.0015 18.6 0.8 0.0049 17.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain PEP-utilisers_N PF05524.8 GAP87660.1 - 0.0026 17.5 3.5 0.0093 15.7 2.4 2.0 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal AAA_19 PF13245.1 GAP87660.1 - 0.0048 16.6 0.0 0.021 14.5 0.0 2.2 1 0 0 1 1 1 1 Part of AAA domain Myosin_N PF02736.14 GAP87660.1 - 0.006 16.2 1.3 0.006 16.2 0.9 2.0 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain GAS PF13851.1 GAP87660.1 - 0.011 14.9 31.3 0.043 12.9 21.7 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4164 PF13747.1 GAP87660.1 - 0.025 14.6 13.9 0.039 14.1 7.7 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) AAA_16 PF13191.1 GAP87660.1 - 0.057 13.4 3.1 0.12 12.4 0.0 3.2 4 0 0 4 4 3 0 AAA ATPase domain AAA_10 PF12846.2 GAP87660.1 - 0.17 11.2 0.0 0.17 11.2 0.0 2.7 2 1 0 2 2 1 0 AAA-like domain DegQ PF08181.6 GAP87660.1 - 0.28 10.9 8.2 0.21 11.3 1.0 3.7 3 0 0 3 3 3 0 DegQ (SacQ) family Reo_sigmaC PF04582.7 GAP87660.1 - 0.58 9.2 4.0 1.3 8.1 1.3 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 GAP87660.1 - 1.1 9.1 16.0 4.8 7.0 8.6 3.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Seryl_tRNA_N PF02403.17 GAP87660.1 - 1.3 9.0 22.3 0.14 12.1 7.2 3.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CENP-Q PF13094.1 GAP87660.1 - 2.2 8.2 24.7 9.1 6.2 17.1 2.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit FlaC_arch PF05377.6 GAP87660.1 - 8.6 6.3 14.3 0.069 13.0 0.5 3.5 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) 2-Hacid_dh_C PF02826.14 GAP87661.1 - 1.7e-52 177.1 0.0 2.6e-52 176.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAP87661.1 - 8.6e-35 119.1 0.0 1.2e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 GAP87661.1 - 3e-05 23.9 0.3 8.2e-05 22.4 0.1 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 GAP87661.1 - 0.00037 19.9 0.3 0.0011 18.3 0.0 2.0 2 0 0 2 2 2 1 ACT domain IlvN PF07991.7 GAP87661.1 - 0.018 14.4 0.1 0.072 12.4 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain AdoHcyase_NAD PF00670.16 GAP87661.1 - 0.026 14.3 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.1 GAP87661.1 - 0.041 14.1 0.0 0.11 12.7 0.0 1.7 2 0 0 2 2 2 0 XdhC Rossmann domain NAP PF00956.13 GAP87662.1 - 1.3e-86 289.6 9.6 1.3e-86 289.6 6.7 1.8 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) YqgF PF14639.1 GAP87662.1 - 0.011 15.3 0.8 0.036 13.6 0.3 2.0 2 0 0 2 2 2 0 Holliday-junction resolvase-like of SPT6 DUF1168 PF06658.7 GAP87662.1 - 0.016 14.7 1.0 0.016 14.7 0.7 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1168) Sld5 PF05916.6 GAP87662.1 - 0.14 12.4 0.5 0.4 10.9 0.4 1.7 1 1 0 1 1 1 0 GINS complex protein P5-ATPase PF12409.3 GAP87663.1 - 2.2e-38 130.7 0.4 5.7e-37 126.2 0.0 2.6 2 0 0 2 2 2 1 P5-type ATPase cation transporter HAD PF12710.2 GAP87663.1 - 1.6e-31 109.9 0.0 3.1e-31 109.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 GAP87663.1 - 8.4e-27 93.6 0.3 2e-26 92.4 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 GAP87663.1 - 1e-16 61.9 0.0 6.4e-15 56.1 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAP87663.1 - 0.0065 15.9 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 GAP87663.1 - 0.02 14.8 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAP87663.1 - 0.13 11.8 0.0 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase WD40 PF00400.27 GAP87664.1 - 7.7e-27 92.1 6.5 2e-08 33.7 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Proteasome PF00227.21 GAP87665.1 - 8.4e-30 103.4 0.0 9.4e-30 103.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DEAD PF00270.24 GAP87666.1 - 2.4e-46 157.2 0.0 5.8e-45 152.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP87666.1 - 3.6e-28 97.2 0.1 7.6e-28 96.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAP87666.1 - 0.0091 15.8 0.0 0.02 14.7 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 GAP87666.1 - 0.033 13.2 0.1 0.069 12.1 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 GAP87666.1 - 0.16 10.3 0.0 0.37 9.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) ABC_membrane PF00664.18 GAP87668.1 - 7.4e-50 169.8 34.8 9.5e-30 103.9 13.8 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 GAP87668.1 - 4.3e-47 159.8 0.0 1e-27 97.1 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 GAP87668.1 - 1.3e-06 28.6 0.2 1.1 9.1 0.0 4.2 3 1 0 3 3 3 2 AAA domain Miro PF08477.8 GAP87668.1 - 1.9e-05 25.1 1.2 0.064 13.7 0.1 2.6 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 GAP87668.1 - 3.5e-05 23.7 0.3 0.1 12.5 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase Zeta_toxin PF06414.7 GAP87668.1 - 4.4e-05 22.6 0.0 0.0098 15.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.1 GAP87668.1 - 0.00011 22.3 0.3 0.05 13.5 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAP87668.1 - 0.00027 21.0 0.0 0.87 9.7 0.0 2.7 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 GAP87668.1 - 0.00039 19.6 0.7 0.38 9.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SMC_N PF02463.14 GAP87668.1 - 0.00044 19.5 0.6 3.7 6.7 0.0 3.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAP87668.1 - 0.00045 19.6 1.2 0.86 9.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 GAP87668.1 - 0.00058 20.6 1.2 0.82 10.5 0.3 3.0 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 GAP87668.1 - 0.002 17.5 0.0 0.45 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 GAP87668.1 - 0.0023 16.8 0.1 0.079 11.8 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.1 GAP87668.1 - 0.0028 17.2 1.0 0.71 9.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 GAP87668.1 - 0.0029 17.9 1.8 1.1 9.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 GAP87668.1 - 0.0035 17.2 2.7 0.16 11.7 0.4 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 TrwB_AAD_bind PF10412.4 GAP87668.1 - 0.016 13.8 0.4 0.94 8.0 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain SRP54 PF00448.17 GAP87668.1 - 0.017 14.5 0.4 0.42 10.0 0.0 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 GAP87668.1 - 0.019 14.3 0.2 4 6.7 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain ArgK PF03308.11 GAP87668.1 - 0.023 13.4 0.8 2.2 7.0 0.1 2.3 2 0 0 2 2 2 0 ArgK protein MobB PF03205.9 GAP87668.1 - 0.032 13.9 1.3 3 7.5 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 GAP87668.1 - 0.04 13.8 0.2 0.19 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 GAP87668.1 - 0.063 13.1 4.5 0.28 10.9 0.3 2.6 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.7 GAP87668.1 - 0.064 12.9 0.3 0.56 9.8 0.0 2.3 2 0 0 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.13 GAP87668.1 - 0.091 12.2 0.1 4.2 6.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.1 GAP87668.1 - 0.11 12.8 1.2 6.5 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 GAP87668.1 - 0.15 11.4 2.2 0.48 9.8 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.1 GAP87668.1 - 0.22 10.5 0.1 4 6.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain DUF912 PF06024.7 GAP87668.1 - 0.8 9.7 4.5 2.2 8.4 0.6 3.0 3 0 0 3 3 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF572 PF04502.8 GAP87669.1 - 2.7 7.1 6.8 4.2 6.4 4.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ebola_NP PF05505.7 GAP87669.1 - 5.1 5.0 5.9 7.8 4.4 4.1 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein Fcf1 PF04900.7 GAP87670.1 - 2e-40 136.9 0.7 4.6e-40 135.7 0.2 1.8 2 0 0 2 2 2 1 Fcf1 Exostosin PF03016.10 GAP87670.1 - 0.0032 16.5 0.0 0.004 16.2 0.0 1.1 1 0 0 1 1 1 1 Exostosin family Dehyd-heme_bind PF09098.5 GAP87670.1 - 0.081 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding Spt20 PF12090.3 GAP87670.1 - 0.082 12.2 0.5 0.14 11.5 0.4 1.5 1 1 0 1 1 1 0 Spt20 family RNase_T PF00929.19 GAP87671.1 - 8.4e-16 58.6 0.0 1.4e-15 57.9 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 GAP87671.1 - 7.7e-05 22.2 0.0 0.00023 20.7 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease zf-C2H2_jaz PF12171.3 GAP87671.1 - 0.0038 17.3 0.2 0.0095 16.0 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF4207 PF13904.1 GAP87671.1 - 0.033 13.5 2.5 0.057 12.7 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) N-SET PF11764.3 GAP87672.1 - 7e-40 136.6 1.3 7e-40 136.6 0.9 2.2 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 GAP87672.1 - 5.9e-23 81.9 0.1 5.9e-23 81.9 0.1 3.8 2 2 0 2 2 2 1 SET domain SET_assoc PF11767.3 GAP87672.1 - 1.5e-21 75.4 0.0 3.4e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated RRM_1 PF00076.17 GAP87672.1 - 0.0074 15.8 0.4 0.1 12.2 0.3 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF228 PF02989.9 GAP87673.1 - 0.21 11.1 1.0 17 4.9 0.1 2.2 2 0 0 2 2 2 0 Lyme disease proteins of unknown function RNA_pol_3_Rpc31 PF11705.3 GAP87673.1 - 2.4 8.0 14.8 2.8 7.8 4.9 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Tropomyosin_1 PF12718.2 GAP87674.1 - 4.2e-45 153.1 35.1 5.4e-45 152.7 24.3 1.2 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 GAP87674.1 - 4.2e-07 29.3 32.5 7.4e-05 21.9 10.8 3.0 1 1 2 3 3 3 3 Tropomyosin Myosin_tail_1 PF01576.14 GAP87674.1 - 0.00021 19.1 33.4 0.00024 18.9 23.1 1.0 1 0 0 1 1 1 1 Myosin tail CENP-F_leu_zip PF10473.4 GAP87674.1 - 0.00049 19.9 35.5 0.0015 18.4 4.4 2.8 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.7 GAP87674.1 - 0.0012 18.6 6.7 0.0012 18.6 4.6 2.1 1 1 1 2 2 2 1 Laminin Domain II ERM PF00769.14 GAP87674.1 - 0.0012 18.4 37.2 0.017 14.6 11.2 2.1 1 1 1 2 2 2 2 Ezrin/radixin/moesin family DUF4200 PF13863.1 GAP87674.1 - 0.0013 18.6 33.3 0.028 14.3 9.9 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4200) bZIP_1 PF00170.16 GAP87674.1 - 0.0019 18.0 33.7 0.086 12.8 2.0 5.5 1 1 3 4 4 4 3 bZIP transcription factor TMF_DNA_bd PF12329.3 GAP87674.1 - 0.0048 16.6 36.1 0.072 12.9 10.4 3.4 1 1 1 2 2 2 1 TATA element modulatory factor 1 DNA binding IncA PF04156.9 GAP87674.1 - 0.0048 16.5 33.5 36 3.8 23.2 2.4 1 1 0 1 1 1 0 IncA protein Mod_r PF07200.8 GAP87674.1 - 0.0052 16.7 27.2 0.072 13.0 11.3 2.1 1 1 1 2 2 2 2 Modifier of rudimentary (Mod(r)) protein TMF_TATA_bd PF12325.3 GAP87674.1 - 0.015 15.0 30.5 0.41 10.3 14.5 3.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding GAS PF13851.1 GAP87674.1 - 0.015 14.5 31.2 0.023 13.8 21.6 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TBPIP PF07106.8 GAP87674.1 - 0.015 14.8 28.0 0.33 10.4 1.5 3.0 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CCDC155 PF14662.1 GAP87674.1 - 0.021 14.4 33.8 0.68 9.4 9.3 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Cast PF10174.4 GAP87674.1 - 0.022 12.8 29.8 0.025 12.6 20.7 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone ATG16 PF08614.6 GAP87674.1 - 0.034 13.9 31.1 1.1 9.0 9.3 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CASP_C PF08172.7 GAP87674.1 - 0.038 13.0 1.5 0.038 13.0 1.0 3.2 1 1 1 2 2 1 0 CASP C terminal Atg14 PF10186.4 GAP87674.1 - 0.046 12.6 27.4 0.12 11.2 12.8 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 GAP87674.1 - 0.078 12.0 34.5 0.41 9.6 15.2 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 GAP87674.1 - 0.11 12.5 27.5 0.15 12.1 0.6 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF3450 PF11932.3 GAP87674.1 - 0.14 11.4 24.2 0.87 8.8 6.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Reo_sigmaC PF04582.7 GAP87674.1 - 0.14 11.2 5.9 1.3 8.1 0.1 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Striatin PF08232.7 GAP87674.1 - 0.15 12.3 25.8 0.51 10.6 11.2 2.3 1 1 1 2 2 2 0 Striatin family Herpes_pp85 PF04637.7 GAP87674.1 - 0.17 10.1 4.8 0.068 11.4 1.7 1.5 1 1 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DivIC PF04977.10 GAP87674.1 - 0.25 10.8 31.9 0.074 12.5 1.4 4.4 1 1 2 4 4 4 0 Septum formation initiator HalX PF08663.5 GAP87674.1 - 0.25 11.3 21.0 2.6 8.0 1.4 4.8 1 1 2 4 4 4 0 HalX domain TACC PF05010.9 GAP87674.1 - 0.25 11.0 19.9 1.5 8.5 13.6 2.0 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) ADIP PF11559.3 GAP87674.1 - 0.25 11.2 34.7 0.75 9.6 3.7 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.9 GAP87674.1 - 0.25 10.9 29.1 0.29 10.7 6.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) BLOC1_2 PF10046.4 GAP87674.1 - 0.33 11.1 21.1 2.1 8.5 0.6 3.9 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nup54 PF13874.1 GAP87674.1 - 0.39 10.3 26.3 1.1 8.9 5.7 2.9 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF972 PF06156.8 GAP87674.1 - 0.39 11.0 27.2 2.7 8.4 0.8 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF904 PF06005.7 GAP87674.1 - 0.42 10.9 37.8 4.6 7.6 7.9 3.8 2 2 1 3 3 3 0 Protein of unknown function (DUF904) PilJ PF13675.1 GAP87674.1 - 0.58 10.5 14.8 1.2 9.5 2.4 3.0 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Lebercilin PF15619.1 GAP87674.1 - 0.66 9.3 33.2 8.9 5.6 14.9 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Jnk-SapK_ap_N PF09744.4 GAP87674.1 - 1 9.3 25.4 1.2 9.0 7.5 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Filament PF00038.16 GAP87674.1 - 1 8.7 27.6 5 6.5 19.1 1.9 1 1 0 1 1 1 0 Intermediate filament protein DUF641 PF04859.7 GAP87674.1 - 1.1 9.0 21.0 0.48 10.1 3.5 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) MIS13 PF08202.6 GAP87674.1 - 1.1 8.2 21.6 6 5.8 5.3 2.1 1 1 1 2 2 2 0 Mis12-Mtw1 protein family DUF869 PF05911.6 GAP87674.1 - 1.1 7.3 26.5 1.8 6.6 7.0 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) Spc7 PF08317.6 GAP87674.1 - 1.2 7.6 28.6 0.15 10.7 11.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein IFT46_B_C PF12317.3 GAP87674.1 - 1.3 8.3 8.1 0.41 9.9 3.5 1.6 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal DUF4140 PF13600.1 GAP87674.1 - 1.3 9.4 23.7 2.4 8.6 3.2 3.3 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF3287 PF11690.3 GAP87674.1 - 1.5 8.9 10.5 0.068 13.2 1.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3287) Syntaxin-6_N PF09177.6 GAP87674.1 - 1.7 9.1 19.4 0.99 9.8 3.4 2.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal WXG100 PF06013.7 GAP87674.1 - 1.8 8.6 15.3 3.3 7.7 0.3 3.8 1 1 3 4 4 4 0 Proteins of 100 residues with WXG AAA_13 PF13166.1 GAP87674.1 - 1.9 6.8 23.7 4.4 5.6 16.5 1.6 1 1 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.7 GAP87674.1 - 2 8.1 34.4 0.91 9.2 19.5 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein NABP PF07990.7 GAP87674.1 - 2.1 7.5 5.8 2.3 7.3 4.0 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP DUF342 PF03961.8 GAP87674.1 - 2.2 6.5 26.5 0.88 7.9 6.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF4201 PF13870.1 GAP87674.1 - 2.3 7.6 26.7 13 5.2 7.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Mnd1 PF03962.10 GAP87674.1 - 2.5 7.7 31.2 6.1 6.4 8.6 2.1 1 1 1 2 2 2 0 Mnd1 family AAA_11 PF13086.1 GAP87674.1 - 2.6 7.5 11.1 4 6.9 7.7 1.2 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 GAP87674.1 - 3.3 4.9 28.8 8.1 3.6 19.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.5 GAP87674.1 - 3.4 7.7 18.3 6.7 6.8 7.3 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family KLRAQ PF10205.4 GAP87674.1 - 3.6 7.6 21.6 1.2 9.2 5.8 2.7 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein CDC37_N PF03234.9 GAP87674.1 - 3.9 7.7 24.3 13 6.0 16.8 1.9 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding HWE_HK PF07536.9 GAP87674.1 - 4.1 7.9 8.8 6.1 7.3 0.4 2.9 1 1 2 3 3 3 0 HWE histidine kinase FlaC_arch PF05377.6 GAP87674.1 - 4.4 7.2 20.5 2.3 8.1 0.2 4.2 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) FliD_C PF07195.7 GAP87674.1 - 4.6 6.4 17.1 11 5.2 7.4 2.8 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF2951 PF11166.3 GAP87674.1 - 5.1 7.0 18.0 2.3 8.1 4.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) HSP70 PF00012.15 GAP87674.1 - 5.3 4.8 18.0 6.6 4.5 12.5 1.3 1 0 0 1 1 1 0 Hsp70 protein Rootletin PF15035.1 GAP87674.1 - 5.7 6.8 29.5 22 4.9 20.4 1.8 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF4164 PF13747.1 GAP87674.1 - 6.1 7.0 27.5 1 9.5 1.1 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) DUF2730 PF10805.3 GAP87674.1 - 6.7 6.4 17.1 0.11 12.2 2.5 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) BRE1 PF08647.6 GAP87674.1 - 6.8 6.7 29.0 1.1 9.3 5.7 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase NPV_P10 PF05531.7 GAP87674.1 - 7 6.9 10.9 6 7.1 0.2 3.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 GAP87674.1 - 8.1 6.2 14.4 6.3 6.6 4.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4600 PF15372.1 GAP87674.1 - 10 6.3 25.8 3.8 7.7 0.9 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4600) Nop25 PF09805.4 GAP87675.1 - 6.7e-37 126.6 13.0 6.7e-37 126.6 9.0 2.1 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) Ferritin-like PF12902.2 GAP87675.1 - 0.013 15.0 2.7 0.022 14.3 1.9 1.3 1 0 0 1 1 1 0 Ferritin-like GvpL_GvpF PF06386.6 GAP87675.1 - 2 7.9 9.5 0.072 12.6 2.5 1.5 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF APH PF01636.18 GAP87676.1 - 1.9e-10 40.8 0.1 1.1e-09 38.3 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAP87676.1 - 1.5e-05 24.6 0.0 2.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase ATP-synt_S1 PF05827.7 GAP87677.1 - 5.1e-36 124.4 0.3 2.2e-35 122.3 0.2 1.8 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Vitelline_membr PF10542.4 GAP87677.1 - 0.058 13.0 0.1 0.058 13.0 0.1 1.9 2 0 0 2 2 2 0 Vitelline membrane cysteine-rich region CENP-N PF05238.8 GAP87677.1 - 0.17 10.9 0.2 0.2 10.6 0.1 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Pro_isomerase PF00160.16 GAP87678.1 - 6.1e-47 159.7 0.5 7.7e-47 159.3 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S13 PF00416.17 GAP87679.1 - 6e-23 81.3 0.3 7.2e-23 81.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 UBA PF00627.26 GAP87679.1 - 0.022 14.5 0.0 3.4 7.6 0.0 2.7 3 0 0 3 3 3 0 UBA/TS-N domain Peptidase_M19 PF01244.16 GAP87680.1 - 7.7e-38 130.1 0.0 9.5e-29 100.3 0.0 2.1 1 1 1 2 2 2 2 Membrane dipeptidase (Peptidase family M19) Tom22 PF04281.8 GAP87681.1 - 7.7e-47 158.2 0.4 9.5e-47 157.9 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Nha1_C PF08619.5 GAP87682.1 - 1.5e-77 261.7 25.0 4e-76 257.0 17.3 2.0 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 GAP87682.1 - 2.6e-67 227.0 21.4 3.1e-67 226.7 14.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 GAP87682.1 - 0.7 9.8 7.2 0.65 9.9 0.2 3.2 3 0 0 3 3 3 0 YrhC-like protein DUF21 PF01595.15 GAP87682.1 - 6.4 6.0 13.3 0.23 10.7 1.2 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF21 FAD_binding_4 PF01565.18 GAP87683.1 - 1.5e-26 92.5 0.0 2.5e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 GAP87683.1 - 7.1e-22 77.9 0.0 1.1e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain HPP PF04982.8 GAP87684.1 - 1.7e-34 118.1 5.4 1.7e-34 118.1 3.7 1.8 2 0 0 2 2 2 1 HPP family CoA_binding_3 PF13727.1 GAP87684.1 - 0.044 13.6 7.0 0.22 11.3 1.7 2.3 1 1 1 2 2 2 0 CoA-binding domain FUSC_2 PF13515.1 GAP87684.1 - 0.2 11.5 12.0 1 9.3 6.8 2.2 1 1 1 2 2 2 0 Fusaric acid resistance protein-like adh_short PF00106.20 GAP87685.1 - 7.3e-16 58.5 0.1 1e-15 58.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP87685.1 - 7.7e-07 28.9 0.0 1.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAP87685.1 - 8.5e-05 22.4 0.1 0.00015 21.5 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAP87685.1 - 0.00021 20.8 0.0 0.00047 19.6 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAP87685.1 - 0.011 15.8 0.4 0.024 14.6 0.3 1.7 1 1 0 1 1 1 0 NADH(P)-binding Scytalone_dh PF02982.9 GAP87686.1 - 2.3e-91 303.5 0.8 2.6e-91 303.3 0.6 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 GAP87686.1 - 2.5e-09 37.1 0.4 3.3e-09 36.7 0.3 1.2 1 0 0 1 1 1 1 SnoaL-like domain RicinB_lectin_2 PF14200.1 GAP87687.1 - 2.4e-25 88.9 3.7 1.1e-15 57.9 1.3 2.0 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 GAP87687.1 - 5.5e-10 39.3 0.5 1.3e-09 38.1 0.3 1.9 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Med22 PF06179.7 GAP87689.1 - 5.5e-13 48.8 0.5 7.3e-13 48.5 0.4 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex PseudoU_synth_1 PF01416.15 GAP87690.1 - 1.2e-23 83.5 0.2 8.1e-10 39.0 0.0 3.3 3 0 0 3 3 3 3 tRNA pseudouridine synthase zf-MYND PF01753.13 GAP87692.1 - 3.9e-07 29.8 12.5 3.9e-07 29.8 8.7 2.6 3 0 0 3 3 3 1 MYND finger SET PF00856.23 GAP87692.1 - 1.3e-06 28.8 0.1 2.1e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 SET domain MFS_1 PF07690.11 GAP87693.1 - 1.4e-49 168.7 58.3 3.6e-39 134.4 27.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF726 PF05277.7 GAP87694.1 - 3.4e-117 391.2 0.6 4.2e-117 390.9 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.15 GAP87694.1 - 0.00043 20.5 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 GAP87694.1 - 0.00048 19.9 0.6 0.0015 18.2 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP87694.1 - 0.0011 18.8 0.2 0.0037 17.1 0.0 1.8 1 1 0 2 2 2 1 Alpha/beta hydrolase family Cutinase PF01083.17 GAP87694.1 - 0.0074 16.0 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 Cutinase Pro-NT_NN PF07421.6 GAP87694.1 - 0.012 15.1 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor PE-PPE PF08237.6 GAP87694.1 - 0.03 13.7 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain TcdA_TcdB_pore PF12920.2 GAP87694.1 - 3.5 5.4 6.2 5.3 4.8 4.3 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain Mpv17_PMP22 PF04117.7 GAP87695.1 - 9.8e-20 69.9 0.2 2.3e-19 68.7 0.1 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Sensor_TM1 PF13755.1 GAP87695.1 - 6.4 6.3 7.8 0.81 9.2 0.1 2.7 3 0 0 3 3 3 0 Sensor N-terminal transmembrane domain E1-E2_ATPase PF00122.15 GAP87696.1 - 9.9e-48 162.1 6.7 2e-47 161.1 4.6 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 GAP87696.1 - 3.4e-27 96.2 1.9 5.9e-27 95.4 1.3 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAP87696.1 - 4.7e-16 59.5 0.0 1.1e-15 58.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 GAP87696.1 - 0.00011 22.2 0.0 0.061 13.4 0.0 2.5 2 0 0 2 2 2 2 Heavy-metal-associated domain APG17 PF04108.7 GAP87697.1 - 1e-100 337.4 7.0 1.2e-100 337.1 4.8 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF745 PF05335.8 GAP87697.1 - 0.0065 16.0 0.4 0.0065 16.0 0.3 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF745) Tropomyosin_1 PF12718.2 GAP87697.1 - 0.032 14.0 8.9 0.11 12.3 2.3 2.8 3 0 0 3 3 3 0 Tropomyosin like Fib_alpha PF08702.5 GAP87697.1 - 0.048 13.7 7.3 0.62 10.1 0.9 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4559 PF15112.1 GAP87697.1 - 0.096 11.8 6.9 0.19 10.8 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) RmuC PF02646.11 GAP87697.1 - 0.13 11.0 5.8 0.97 8.2 0.1 3.1 3 0 0 3 3 3 0 RmuC family Prefoldin_2 PF01920.15 GAP87697.1 - 0.14 11.9 7.9 1.4 8.7 0.4 3.0 3 0 0 3 3 3 0 Prefoldin subunit Baculo_PEP_C PF04513.7 GAP87697.1 - 0.15 11.8 7.3 2.6 7.8 1.0 3.3 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 GAP87697.1 - 0.17 12.1 5.0 1.1 9.5 0.4 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4358 PF14270.1 GAP87697.1 - 0.38 10.6 3.3 0.78 9.6 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4358) V_ATPase_I PF01496.14 GAP87697.1 - 0.55 8.0 3.2 0.82 7.4 0.7 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family TBPIP PF07106.8 GAP87697.1 - 0.92 9.0 7.2 4.1 6.9 0.5 2.6 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Med4 PF10018.4 GAP87697.1 - 0.98 8.7 8.8 0.98 8.7 0.1 3.0 3 0 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 LOH1CR12 PF10158.4 GAP87697.1 - 1.7 8.4 7.1 4 7.2 0.1 3.6 3 2 2 5 5 5 0 Tumour suppressor protein Mer2 PF09074.5 GAP87697.1 - 1.9 8.3 8.1 0.5 10.2 0.6 2.9 2 2 0 2 2 2 0 Mer2 Bacillus_HBL PF05791.6 GAP87697.1 - 2.9 7.2 9.1 3.5 6.9 0.2 3.5 4 0 0 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) TPR_MLP1_2 PF07926.7 GAP87697.1 - 5.3 6.8 11.0 5.1 6.8 1.9 3.5 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein SlyX PF04102.7 GAP87697.1 - 8.6 6.8 9.0 1.9 8.9 1.6 3.0 2 0 0 2 2 2 0 SlyX Flavokinase PF01687.12 GAP87698.1 - 2.7e-12 46.6 0.0 4.8e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Riboflavin kinase MFS_1 PF07690.11 GAP87701.1 - 4.2e-31 107.9 31.2 4.2e-31 107.9 21.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MMPL PF03176.10 GAP87701.1 - 6.8 5.2 12.1 0.56 8.8 1.0 2.4 2 0 0 2 2 2 0 MMPL family Ferric_reduct PF01794.14 GAP87702.1 - 4.9e-14 52.4 12.7 4.9e-14 52.4 8.8 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 GAP87702.1 - 9.5e-11 41.5 0.0 1.8e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 GAP87702.1 - 1.2e-07 31.7 0.0 0.00035 20.5 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain DUF218 PF02698.12 GAP87703.1 - 5.6e-32 110.3 0.0 8.1e-32 109.8 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain DUF1866 PF08952.6 GAP87703.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) Methyltransf_23 PF13489.1 GAP87704.1 - 7.2e-10 38.8 0.0 1e-09 38.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP87704.1 - 1e-08 35.5 0.0 3.4e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP87704.1 - 6.6e-07 29.7 0.0 1.4e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP87704.1 - 2.7e-06 27.9 0.0 5.5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP87704.1 - 2.2e-05 24.4 0.0 3.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP87704.1 - 0.00014 22.1 0.0 0.00025 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 GAP87704.1 - 0.021 14.8 0.0 0.067 13.1 0.0 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 GAP87705.1 - 1e-19 70.8 0.0 1.6e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP87705.1 - 1.2e-10 41.9 0.0 5.8e-09 36.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP87705.1 - 3.5e-06 26.6 0.0 4.2e-05 23.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 GAP87705.1 - 8.4e-06 25.8 0.0 2.5e-05 24.3 0.0 1.8 2 1 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 GAP87705.1 - 1.9e-05 23.8 0.0 4.8e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.7 GAP87705.1 - 3.3e-05 24.2 0.0 0.00025 21.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP87705.1 - 0.00014 22.3 0.0 0.00027 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP87705.1 - 0.00073 19.8 0.0 0.0028 18.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP87705.1 - 0.00078 19.4 0.0 0.0034 17.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAP87705.1 - 0.021 14.1 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain ketoacyl-synt PF00109.21 GAP87706.1 - 3.1e-79 266.0 0.0 5.8e-79 265.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 GAP87706.1 - 1.8e-56 190.6 0.0 8.4e-55 185.2 0.0 3.3 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.16 GAP87706.1 - 4.1e-49 167.6 0.0 7.1e-49 166.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 GAP87706.1 - 1.1e-43 149.5 0.0 1.7e-43 148.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 GAP87706.1 - 7.7e-43 146.2 0.3 4.8e-42 143.7 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAP87706.1 - 1.1e-33 115.6 0.0 6.4e-33 113.1 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 GAP87706.1 - 1.4e-17 63.9 0.0 4.4e-17 62.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 GAP87706.1 - 1.3e-16 60.2 0.1 6e-16 58.1 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 GAP87706.1 - 3.4e-13 49.6 0.0 7.4e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP87706.1 - 6.8e-11 41.9 0.0 1.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP87706.1 - 3.2e-09 37.1 0.0 1.8e-08 34.7 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP87706.1 - 1.5e-08 35.1 0.0 8.7e-08 32.7 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.20 GAP87706.1 - 1.7e-06 28.1 0.7 8.5e-06 25.9 0.0 2.5 3 0 0 3 3 3 1 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.1 GAP87706.1 - 5.7e-06 27.2 0.0 2.9e-05 24.9 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ubie_methyltran PF01209.13 GAP87706.1 - 3.7e-05 22.9 0.0 7.9e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 GAP87706.1 - 6.8e-05 22.3 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase ADH_N PF08240.7 GAP87706.1 - 9.8e-05 22.0 0.2 0.00022 20.9 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 GAP87706.1 - 0.00024 20.1 0.1 0.00054 19.0 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_25 PF13649.1 GAP87706.1 - 0.0039 17.5 0.0 0.016 15.5 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 GAP87706.1 - 0.031 13.6 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF938 PF06080.7 GAP87706.1 - 0.082 12.4 0.3 1.8 8.0 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF938) Cofilin_ADF PF00241.15 GAP87707.1 - 7.6e-20 71.0 0.0 1.2e-08 34.9 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Mito_carr PF00153.22 GAP87708.1 - 8.8e-70 230.4 0.9 1.2e-22 79.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MtrF PF09472.5 GAP87708.1 - 0.03 13.5 0.1 0.12 11.6 0.1 2.0 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) WD40 PF00400.27 GAP87709.1 - 1.9e-54 179.7 14.3 3.7e-10 39.2 0.1 8.0 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 GAP87709.1 - 1.2e-12 47.3 1.3 2.9e-12 46.1 0.9 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAP87709.1 - 3.8e-08 32.7 1.4 3.8e-08 32.7 1.0 2.3 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.3 GAP87709.1 - 4.8e-08 31.5 7.9 0.011 13.9 0.1 4.4 2 2 2 4 4 4 4 Nucleoporin Nup120/160 eIF2A PF08662.6 GAP87709.1 - 0.031 13.9 0.0 1.4 8.5 0.0 2.2 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A CSTF_C PF14304.1 GAP87709.1 - 0.12 11.6 2.2 0.87 8.9 0.1 2.5 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal Glyco_hydro_47 PF01532.15 GAP87711.1 - 3.4e-156 520.4 0.0 4e-156 520.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TauD PF02668.11 GAP87712.1 - 9e-29 100.9 0.4 1.7e-28 99.9 0.1 1.6 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 GAP87712.1 - 0.023 13.5 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 CsiD Mito_carr PF00153.22 GAP87713.1 - 3.2e-18 65.2 0.4 4.3e-12 45.5 0.0 3.9 5 1 0 5 5 5 2 Mitochondrial carrier protein DUF3818 PF12825.2 GAP87714.1 - 2.9e-41 141.3 1.0 1.2e-28 99.7 0.1 2.2 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 GAP87714.1 - 8.7e-25 86.9 0.0 3e-24 85.1 0.0 2.0 2 0 0 2 2 2 1 PX-associated PEX11 PF05648.9 GAP87714.1 - 0.018 14.3 0.0 0.63 9.2 0.0 2.6 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) UPF0137 PF03677.8 GAP87714.1 - 0.04 13.4 0.3 0.1 12.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0137) Peptidase_M35 PF02102.10 GAP87715.1 - 7.3e-33 113.6 14.9 9e-33 113.3 10.3 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 GAP87715.1 - 8.5e-07 29.5 1.3 3.2e-06 27.7 0.9 2.0 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 GAP87715.1 - 1.4e-05 24.6 0.6 1.4e-05 24.6 0.4 1.6 2 0 0 2 2 2 1 Putative peptidase family DUF4352 PF11611.3 GAP87715.1 - 0.035 14.2 0.4 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4352) Glyco_hydro_3 PF00933.16 GAP87716.1 - 2.7e-84 282.6 0.0 4e-84 282.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAP87716.1 - 8.3e-42 143.2 0.2 3.6e-40 137.8 0.0 2.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAP87716.1 - 8.4e-21 73.6 0.1 1.5e-20 72.8 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain MARVEL PF01284.18 GAP87717.1 - 3.5e-20 72.2 6.0 4.9e-20 71.8 4.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain QCR10 PF09796.4 GAP87717.1 - 2.2 7.9 4.4 6.4 6.5 0.7 2.5 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Claudin_2 PF13903.1 GAP87717.1 - 4.8 6.8 13.3 6.6 6.3 4.2 2.6 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction PBP PF01161.15 GAP87718.1 - 2.4e-14 53.4 0.0 3.5e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein zf-RING_2 PF13639.1 GAP87718.1 - 0.0001 22.0 3.3 0.00012 21.8 0.1 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAP87718.1 - 0.00057 19.8 0.5 0.00057 19.8 0.3 3.3 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAP87718.1 - 0.0017 17.9 0.2 0.0017 17.9 0.1 3.4 4 1 0 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.20 GAP87718.1 - 0.0019 17.7 0.9 0.009 15.6 0.2 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAP87718.1 - 5.3 6.9 7.6 0.17 11.7 0.3 2.3 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING VWA_3 PF13768.1 GAP87719.1 - 1.4e-28 99.5 0.0 2.7e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 GAP87719.1 - 1.6e-19 69.7 0.0 3.5e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 GAP87719.1 - 8.5e-11 42.2 0.0 1.7e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 GAP87719.1 - 2.8e-09 36.2 0.0 5.5e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 GAP87719.1 - 1.4e-05 24.8 0.0 2.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 GAP87719.1 - 0.14 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein RPE65 PF03055.10 GAP87720.1 - 3.5e-120 401.8 0.0 5.7e-120 401.1 0.0 1.3 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF1264 PF06884.6 GAP87720.1 - 2.2e-28 98.8 1.5 6.4e-28 97.3 1.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1264) SnoaL_4 PF13577.1 GAP87720.1 - 2e-24 85.9 2.4 3.1e-23 82.0 0.3 2.8 3 0 0 3 3 3 1 SnoaL-like domain TBPIP PF07106.8 GAP87720.1 - 0.064 12.7 0.1 0.27 10.7 0.0 1.9 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1192 PF06698.6 GAP87720.1 - 0.074 12.8 1.2 0.16 11.8 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DivIC PF04977.10 GAP87720.1 - 0.62 9.5 2.0 0.6 9.6 0.1 1.9 2 0 0 2 2 2 0 Septum formation initiator APH PF01636.18 GAP87721.1 - 3.4e-07 30.2 0.1 9.9e-07 28.7 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Arf PF00025.16 GAP87722.1 - 3.3e-68 228.3 0.8 3.7e-68 228.1 0.6 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 GAP87722.1 - 9.2e-14 51.1 0.0 1.1e-13 50.9 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 GAP87722.1 - 1.5e-12 46.9 0.8 3.6e-07 29.2 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 GAP87722.1 - 2.3e-10 40.0 0.0 2.7e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAP87722.1 - 1.7e-09 37.6 0.0 2.2e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAP87722.1 - 5.5e-09 36.5 0.0 7.5e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 GAP87722.1 - 2.5e-08 33.3 0.0 3e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 GAP87722.1 - 3e-06 26.8 0.0 0.00018 21.0 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain NACHT PF05729.7 GAP87722.1 - 0.0032 17.1 0.0 0.085 12.5 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.1 GAP87722.1 - 0.012 16.3 0.0 0.017 15.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 GAP87722.1 - 0.053 12.7 0.2 0.14 11.4 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.4 GAP87722.1 - 0.059 12.8 0.1 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 GAP87722.1 - 0.075 12.9 0.0 0.18 11.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain APH PF01636.18 GAP87725.1 - 3.4e-09 36.8 0.0 4.7e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 GAP87725.1 - 0.00042 19.5 0.0 0.00082 18.6 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.9 GAP87725.1 - 0.011 14.7 0.0 0.098 11.6 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase Choline_kinase PF01633.15 GAP87725.1 - 0.05 13.1 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.6 GAP87725.1 - 0.058 12.0 0.0 0.081 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DUF2392 PF10288.4 GAP87726.1 - 4.5e-09 36.6 0.0 2.5e-08 34.1 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) ATP_bind_3 PF01171.15 GAP87726.1 - 0.054 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 PP-loop family Mito_carr PF00153.22 GAP87727.1 - 9.9e-50 166.2 0.5 3.4e-20 71.5 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein FHA PF00498.21 GAP87728.1 - 1.6e-15 56.9 0.0 3.5e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 GAP87728.1 - 2.1e-07 30.6 8.8 3.5e-07 29.9 6.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAP87728.1 - 0.00032 20.7 4.8 0.0006 19.8 3.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 GAP87728.1 - 0.00094 18.7 8.4 0.0016 18.0 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 GAP87728.1 - 0.014 15.4 4.3 0.023 14.7 3.0 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_5 PF14634.1 GAP87728.1 - 0.016 14.9 5.5 0.027 14.2 3.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAP87728.1 - 0.061 13.3 10.0 0.11 12.5 6.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAP87728.1 - 0.082 12.7 2.7 0.14 11.9 1.8 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H PF13771.1 GAP87728.1 - 0.082 13.0 1.3 0.17 12.0 0.9 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD PF00628.24 GAP87728.1 - 0.37 10.5 5.7 0.7 9.6 4.0 1.5 1 0 0 1 1 1 0 PHD-finger Peptidase_M16_C PF05193.16 GAP87729.1 - 9.9e-47 158.9 0.0 3.4e-46 157.2 0.0 2.0 1 1 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 GAP87729.1 - 1.7e-39 134.9 0.0 4.6e-39 133.5 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) AAA_5 PF07728.9 GAP87729.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Bac_rhamnosid PF05592.6 GAP87730.1 - 5.1e-28 97.5 0.1 3.4e-14 51.9 0.1 3.1 3 0 0 3 3 3 3 Bacterial alpha-L-rhamnosidase GDE_C PF06202.9 GAP87730.1 - 1.2e-05 24.2 0.0 1.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase DUF608 PF04685.8 GAP87730.1 - 9.2e-05 21.3 0.2 0.00013 20.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF608 ELFV_dehydrog PF00208.16 GAP87731.1 - 2.4e-59 200.8 0.0 3.8e-59 200.2 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 GAP87731.1 - 1.6e-22 78.9 0.0 2.4e-17 61.7 0.0 2.3 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 GAP87731.1 - 0.0042 16.6 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Aminotran_5 PF00266.14 GAP87732.1 - 3.7e-12 45.6 0.0 3.8e-11 42.3 0.0 2.2 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 GAP87732.1 - 0.00013 20.3 0.0 0.00042 18.7 0.0 1.7 1 1 1 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 GAP87732.1 - 0.00097 18.2 0.0 0.0037 16.3 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family zf-CHY PF05495.7 GAP87733.1 - 4.8e-14 52.2 22.4 6.3e-14 51.8 15.5 1.1 1 0 0 1 1 1 1 CHY zinc finger Zn_Tnp_IS1595 PF12760.2 GAP87733.1 - 0.063 13.0 14.0 0.64 9.8 7.0 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Tmemb_55A PF09788.4 GAP87733.1 - 0.084 11.9 7.9 0.1 11.7 5.4 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A PAZ_siRNAbind PF12212.3 GAP87733.1 - 0.16 11.5 0.2 9.6 5.9 0.0 2.9 3 0 0 3 3 3 0 Piwi/Argonaute/Zwille siRNA-binding domain Zn-ribbon_8 PF09723.5 GAP87733.1 - 0.18 11.7 13.0 2.1 8.3 4.9 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Cytochrome_C7 PF14522.1 GAP87733.1 - 1.1 8.9 16.2 1.7 8.2 11.3 1.4 1 0 0 1 1 1 0 Cytochrome c7 zf-RING_3 PF14369.1 GAP87733.1 - 1.4 8.9 10.4 1.1 9.3 4.9 2.4 1 1 1 2 2 2 0 zinc-finger DUF3797 PF12677.2 GAP87733.1 - 2 8.1 0.0 2 8.1 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF3797) HypA PF01155.14 GAP87733.1 - 6.5 6.4 13.3 69 3.1 9.2 2.1 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family C1_4 PF07975.7 GAP87733.1 - 7 6.7 17.1 5.8 7.0 5.4 2.7 1 1 2 3 3 3 0 TFIIH C1-like domain Evr1_Alr PF04777.8 GAP87733.1 - 9.5 6.1 12.9 65 3.5 8.9 2.3 1 1 0 1 1 1 0 Erv1 / Alr family Proteasome PF00227.21 GAP87734.1 - 1.9e-55 187.0 0.2 2.8e-55 186.5 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 GAP87734.1 - 1.8e-12 46.3 0.1 1.8e-12 46.3 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Zn_clus PF00172.13 GAP87735.1 - 7.7e-07 28.9 10.3 1.4e-06 28.1 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CorA PF01544.13 GAP87736.1 - 5.8e-42 143.7 0.0 7.3e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SPC12 PF06645.8 GAP87737.1 - 5.1e-28 96.6 0.1 6.2e-28 96.4 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Ribonucleas_3_3 PF14622.1 GAP87737.1 - 0.029 14.3 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease-III-like zf-rbx1 PF12678.2 GAP87738.1 - 1.5e-34 117.8 14.1 1.9e-34 117.5 9.8 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 GAP87738.1 - 1.2e-16 60.3 10.2 1.5e-16 59.9 7.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 GAP87738.1 - 2e-06 27.5 12.8 1.3e-05 24.9 8.9 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 GAP87738.1 - 0.0076 15.8 10.5 0.95 9.1 7.5 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAP87738.1 - 0.0078 15.8 13.3 0.14 11.8 9.2 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAP87738.1 - 0.17 11.9 13.7 0.19 11.7 6.2 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 GAP87738.1 - 1 9.3 9.6 6.3 6.8 6.8 2.1 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H PF13771.1 GAP87738.1 - 1.1 9.4 10.7 80 3.4 7.5 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 GAP87738.1 - 1.3 9.0 10.3 4.1 7.4 7.1 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_5 PF14634.1 GAP87738.1 - 2 8.2 12.8 19 5.0 8.9 2.4 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 GAP87738.1 - 4.3 7.1 8.2 1.1e+02 2.6 5.7 2.3 1 1 0 1 1 1 0 RING-type zinc-finger PNRC PF15365.1 GAP87739.1 - 3.4e-06 26.9 1.5 3.4e-06 26.9 1.0 3.6 3 1 0 3 3 3 1 Proline-rich nuclear receptor coactivator Tyr-DNA_phospho PF06087.7 GAP87740.1 - 2.2e-72 244.0 0.0 2.8e-72 243.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.15 GAP87740.1 - 0.0011 18.3 0.1 0.0011 18.3 0.0 3.9 4 0 0 4 4 4 1 Ubiquitin interaction motif PLDc_2 PF13091.1 GAP87740.1 - 0.0022 17.7 0.0 0.019 14.7 0.0 2.3 2 0 0 2 2 2 1 PLD-like domain FAM110_C PF14160.1 GAP87740.1 - 0.014 16.2 0.1 1.1 10.2 0.0 3.0 2 1 1 3 3 3 0 Centrosome-associated C terminus Gti1_Pac2 PF09729.4 GAP87741.1 - 2.5e-59 199.8 0.0 3.8e-59 199.3 0.0 1.3 1 0 0 1 1 1 1 Gti1/Pac2 family CDP-OH_P_transf PF01066.16 GAP87742.1 - 2.1e-15 56.8 4.6 2.1e-15 56.8 3.2 1.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase GIDA PF01134.17 GAP87743.1 - 9.9e-157 521.8 0.0 1.2e-156 521.5 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 GAP87743.1 - 7.1e-17 61.2 0.0 2.2e-16 59.6 0.0 1.9 1 0 0 1 1 1 1 GidA associated domain 3 FAD_oxidored PF12831.2 GAP87743.1 - 5.8e-07 28.9 0.4 1e-06 28.1 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAP87743.1 - 1e-06 28.7 0.4 2.7e-06 27.4 0.3 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 GAP87743.1 - 0.00027 20.5 0.4 0.00051 19.6 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.19 GAP87743.1 - 0.00056 18.9 3.0 0.69 8.7 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAP87743.1 - 0.0076 15.1 4.7 0.0076 15.1 3.3 2.1 2 1 1 3 3 3 1 FAD binding domain HI0933_like PF03486.9 GAP87743.1 - 0.014 13.8 1.6 0.16 10.3 0.4 2.2 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.1 GAP87743.1 - 0.073 13.3 0.1 0.18 12.0 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.22 GAP87743.1 - 0.13 12.7 0.4 0.31 11.4 0.3 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3602 PF12223.3 GAP87744.1 - 1.1e-09 38.4 15.8 3.9e-05 23.9 4.5 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Ribosomal_L24e PF01246.15 GAP87745.1 - 5.8e-31 106.1 2.8 1.2e-30 105.1 2.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e DnaJ PF00226.26 GAP87746.1 - 4.3e-08 32.7 0.0 5.9e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 GAP87746.1 - 2.4e-06 27.3 0.0 2.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Pam16 DUF3918 PF13056.1 GAP87746.1 - 8.3 5.8 6.5 0.61 9.4 0.8 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3918) Ku PF02735.11 GAP87748.1 - 3.2e-24 85.4 0.0 6.1e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 GAP87748.1 - 6e-23 81.4 0.9 7.1e-23 81.2 0.0 1.5 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 GAP87748.1 - 7e-15 54.9 0.1 1.6e-14 53.8 0.1 1.6 1 0 0 1 1 1 1 Ku C terminal domain like VWA_2 PF13519.1 GAP87748.1 - 2.7e-08 34.1 0.0 1.9e-07 31.3 0.0 2.3 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 GAP87748.1 - 0.0006 19.5 0.0 0.0013 18.4 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4149 PF13664.1 GAP87749.1 - 2e-24 85.5 1.6 2e-24 85.5 1.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF1510 PF07423.6 GAP87749.1 - 0.014 14.8 1.0 0.018 14.4 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PGC7_Stella PF15549.1 GAP87750.1 - 0.047 13.6 1.6 0.065 13.2 1.1 1.3 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain Gly-rich_Ago1 PF12764.2 GAP87750.1 - 1.6 9.4 5.9 1.6 9.4 3.2 1.7 1 1 0 1 1 1 0 Glycine-rich region of argonaut DUF1295 PF06966.7 GAP87751.1 - 4.8e-36 124.2 7.8 6e-36 123.9 5.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 GAP87751.1 - 0.041 14.0 0.6 0.51 10.5 0.0 2.5 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Topoisom_bac PF01131.15 GAP87752.1 - 5e-90 302.2 0.0 2.6e-84 283.3 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.17 GAP87752.1 - 2.4e-21 75.5 0.0 5.4e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Toprim domain RdRP_1 PF00680.15 GAP87752.1 - 0.069 11.3 0.0 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase Stb3 PF10330.4 GAP87753.1 - 7e-36 121.8 0.0 1.3e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein zf-C2H2 PF00096.21 GAP87755.1 - 1.6e-07 31.2 18.7 1.4e-05 25.1 2.6 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAP87755.1 - 2.5e-05 24.3 3.8 2.5e-05 24.3 2.7 3.5 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAP87755.1 - 0.00049 20.2 0.9 0.00049 20.2 0.6 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAP87755.1 - 0.00082 19.4 1.0 0.00082 19.4 0.7 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAP87755.1 - 0.42 10.8 3.6 0.29 11.3 0.5 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 GAP87755.1 - 0.71 9.8 4.1 0.55 10.2 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger DUF629 PF04780.7 GAP87755.1 - 3.1 6.1 7.0 2.1 6.7 1.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.2 GAP87755.1 - 3.2 7.8 9.7 15 5.7 5.4 2.7 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-TRAF PF02176.13 GAP87755.1 - 3.6 8.0 7.3 1.5 9.2 2.3 2.2 1 1 1 2 2 2 0 TRAF-type zinc finger EF-hand_6 PF13405.1 GAP87756.1 - 1.5e-11 43.1 0.1 2.5e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 GAP87756.1 - 2.4e-10 38.9 1.3 0.00056 19.0 0.2 2.4 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 GAP87756.1 - 1.4e-07 30.4 4.7 0.00034 19.8 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 GAP87756.1 - 1.6e-07 31.3 1.8 1.7e-05 24.8 0.1 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 GAP87756.1 - 1.1e-05 24.9 0.0 0.15 11.7 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.1 GAP87756.1 - 0.015 15.1 0.0 4.4 7.2 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain DUF1470 PF07336.6 GAP87756.1 - 0.16 12.3 3.2 0.47 10.7 1.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1470) TPR_11 PF13414.1 GAP87757.1 - 4e-48 160.9 16.4 3.7e-21 74.5 0.3 5.6 4 1 1 5 5 5 5 TPR repeat TPR_1 PF00515.23 GAP87757.1 - 4.8e-39 130.4 10.1 2.8e-08 33.0 0.1 8.9 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.12 GAP87757.1 - 2e-34 114.6 16.2 7.2e-06 25.5 0.2 8.9 8 1 1 9 9 9 7 Tetratricopeptide repeat DnaJ PF00226.26 GAP87757.1 - 1.6e-28 98.2 2.5 8.9e-28 95.8 1.7 2.4 1 0 0 1 1 1 1 DnaJ domain TPR_16 PF13432.1 GAP87757.1 - 2.2e-25 88.6 15.7 2.6e-09 37.4 0.2 6.2 5 2 1 6 6 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 GAP87757.1 - 3.5e-22 78.5 14.7 2.4e-09 37.4 0.0 5.8 3 3 2 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAP87757.1 - 2.6e-20 71.0 15.1 7.1e-06 26.2 0.1 8.3 4 2 4 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 GAP87757.1 - 8.5e-18 62.7 6.7 0.0013 18.3 0.0 7.2 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 GAP87757.1 - 1.7e-17 62.1 10.1 5.9e-05 22.9 0.0 7.0 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAP87757.1 - 5.9e-16 58.1 15.1 9.8e-08 31.8 0.1 5.6 3 2 2 5 5 5 5 Tetratricopeptide repeat Apc3 PF12895.2 GAP87757.1 - 6.7e-14 51.7 8.2 7.4e-08 32.4 0.1 3.9 3 1 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 GAP87757.1 - 2.2e-12 45.7 10.6 0.17 11.7 0.0 7.6 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 GAP87757.1 - 6.7e-12 45.0 11.3 0.00022 20.9 0.4 5.6 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 GAP87757.1 - 1.1e-08 34.9 16.1 0.0055 17.0 0.0 8.0 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_15 PF13429.1 GAP87757.1 - 7.1e-08 31.8 8.0 0.00025 20.1 0.1 4.2 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 GAP87757.1 - 1.4e-05 25.0 0.4 0.29 11.6 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.12 GAP87757.1 - 0.00019 21.7 5.4 0.18 12.1 0.0 4.2 2 2 1 3 3 3 1 Bacterial transcriptional activator domain TPR_21 PF09976.4 GAP87757.1 - 0.00065 19.6 5.3 0.06 13.2 0.0 3.5 3 2 0 3 3 3 2 Tetratricopeptide repeat NatB_MDM20 PF09797.4 GAP87757.1 - 0.0015 17.3 0.0 0.0028 16.4 0.0 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit SNAP PF14938.1 GAP87757.1 - 0.0017 17.5 9.1 0.0081 15.3 0.6 3.4 3 1 0 3 3 3 1 Soluble NSF attachment protein, SNAP Coatomer_E PF04733.9 GAP87757.1 - 0.003 16.8 1.0 0.11 11.6 0.0 3.0 3 1 0 3 3 3 1 Coatomer epsilon subunit TPR_10 PF13374.1 GAP87757.1 - 0.003 17.4 9.5 2.8 7.9 0.2 4.9 5 1 0 5 5 4 1 Tetratricopeptide repeat NARP1 PF12569.3 GAP87757.1 - 0.0045 15.8 5.7 0.37 9.4 0.9 3.1 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 SHNi-TPR PF10516.4 GAP87757.1 - 0.016 14.4 0.8 5.4 6.3 0.1 3.5 3 0 0 3 3 3 0 SHNi-TPR ChAPs PF09295.5 GAP87757.1 - 0.02 13.6 0.2 0.04 12.6 0.0 1.5 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.1 GAP87757.1 - 0.037 14.1 13.3 0.5 10.5 0.1 4.7 3 2 1 4 4 4 0 Tetratricopeptide repeat DUF3856 PF12968.2 GAP87757.1 - 0.059 13.1 5.1 46 3.8 0.0 5.7 4 2 0 5 5 5 0 Domain of Unknown Function (DUF3856) Alkyl_sulf_dimr PF14863.1 GAP87757.1 - 0.062 13.5 1.6 1.2 9.3 0.0 3.0 3 1 0 3 3 3 0 Alkyl sulfatase dimerisation DUF3366 PF11846.3 GAP87757.1 - 0.48 10.2 2.0 0.78 9.5 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3366) MFS_1 PF07690.11 GAP87758.1 - 1.3e-17 63.6 38.3 4.5e-09 35.4 8.8 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 GAP87758.1 - 2.1e-05 23.1 1.7 2.1e-05 23.1 1.2 3.1 4 0 0 4 4 4 2 MFS/sugar transport protein LacY_symp PF01306.14 GAP87758.1 - 7.2 5.0 12.0 0.12 10.9 1.7 2.5 3 0 0 3 3 3 0 LacY proton/sugar symporter MBOAT PF03062.14 GAP87759.1 - 3.7e-17 62.4 19.1 1.4e-16 60.5 12.6 2.0 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 GAP87759.1 - 0.00049 20.1 0.5 0.0014 18.6 0.3 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family WD40 PF00400.27 GAP87760.1 - 5.1e-48 159.3 23.2 6.7e-10 38.4 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 GAP87760.1 - 0.003 17.3 0.0 2.4 7.8 0.0 3.3 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 GAP87760.1 - 0.032 12.9 0.2 0.62 8.7 0.1 2.9 2 2 1 3 3 3 0 Nup133 N terminal like Endonuclease_NS PF01223.18 GAP87762.1 - 6.6e-60 202.2 0.0 9.2e-60 201.8 0.0 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Shikimate_DH PF01488.15 GAP87762.1 - 0.022 14.8 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Rhamno_transf PF11316.3 GAP87762.1 - 0.14 11.3 0.0 0.32 10.1 0.0 1.5 1 1 0 1 1 1 0 Putative rhamnosyl transferase Formyl_trans_N PF00551.14 GAP87763.1 - 3e-32 111.6 0.0 3.8e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Barstar PF01337.13 GAP87763.1 - 0.033 14.0 0.0 0.082 12.7 0.0 1.7 2 0 0 2 2 2 0 Barstar (barnase inhibitor) Zip PF02535.17 GAP87764.1 - 3.8e-35 121.4 1.1 6.2e-35 120.7 0.8 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter Hexapep_2 PF14602.1 GAP87767.1 - 2.5e-16 58.9 8.1 3.2e-11 42.5 0.8 3.1 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 GAP87767.1 - 1.2e-15 56.2 8.5 2.9e-11 42.3 1.4 3.3 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 GAP87767.1 - 7.9e-10 38.6 0.6 1.3e-09 37.9 0.4 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Acetyltransf_11 PF13720.1 GAP87767.1 - 0.12 12.6 0.1 0.27 11.5 0.0 1.6 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 ICMT PF04140.9 GAP87768.1 - 7.4e-29 99.8 0.0 1.8e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 GAP87768.1 - 2.7e-12 46.7 0.5 2.7e-12 46.7 0.3 2.5 2 1 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 GAP87768.1 - 0.0031 16.8 0.4 0.0038 16.5 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF973 PF06157.6 GAP87768.1 - 0.0053 15.7 0.0 0.01 14.8 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF973) Sec63 PF02889.11 GAP87769.1 - 1.1e-44 152.9 0.0 8.4e-44 150.0 0.0 2.2 2 1 0 2 2 2 1 Sec63 Brl domain DnaJ PF00226.26 GAP87769.1 - 3.4e-16 58.7 0.1 1e-15 57.1 0.1 1.9 1 0 0 1 1 1 1 DnaJ domain DUF2347 PF09804.4 GAP87770.1 - 7.7e-107 356.7 0.0 1e-106 356.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 GAP87770.1 - 5e-44 150.4 0.0 7.7e-44 149.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.5 GAP87770.1 - 4.2e-07 29.6 0.0 8.6e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 GAP87770.1 - 6.9e-06 24.7 0.0 0.00095 17.7 0.0 2.2 2 0 0 2 2 2 2 Transport protein Avl9 adh_short PF00106.20 GAP87771.1 - 1.1e-18 67.6 11.1 2e-17 63.6 7.7 2.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP87771.1 - 3.1e-10 39.9 2.7 2.7e-09 36.9 1.8 2.3 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAP87771.1 - 1.2e-08 35.0 0.0 2.9e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 GAP87771.1 - 0.00088 19.3 0.1 0.0014 18.7 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 GAP87771.1 - 0.0026 18.1 0.2 0.0051 17.1 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3Beta_HSD PF01073.14 GAP87771.1 - 0.005 15.5 0.0 0.0082 14.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAP87771.1 - 0.0078 16.2 0.6 0.013 15.4 0.4 1.3 1 0 0 1 1 1 1 NADH(P)-binding NtA PF03146.10 GAP87771.1 - 0.064 12.8 0.0 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 Agrin NtA domain Epimerase PF01370.16 GAP87771.1 - 0.12 11.8 0.5 0.21 10.9 0.1 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family LysM PF01476.15 GAP87772.1 - 1.9e-14 53.2 0.0 4e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 LysM domain ESSS PF10183.4 GAP87773.1 - 0.65 10.4 2.0 1.1 9.6 0.3 2.0 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Tyrosinase PF00264.15 GAP87774.1 - 6.7e-43 147.4 0.0 9.2e-43 146.9 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Condensation PF00668.15 GAP87775.1 - 0.059 12.2 0.0 1.7 7.3 0.0 2.6 3 0 0 3 3 3 0 Condensation domain GST_C_3 PF14497.1 GAP87776.1 - 1.1e-11 45.0 0.0 1.7e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAP87776.1 - 8.3e-10 38.5 0.0 3.3e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAP87776.1 - 7.2e-06 25.8 0.0 2.3e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAP87776.1 - 0.0001 22.3 0.2 0.24 11.6 0.0 2.8 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAP87776.1 - 0.00092 19.3 0.0 0.0018 18.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain N_methyl PF07963.7 GAP87777.1 - 0.045 13.5 3.0 0.22 11.3 2.1 2.2 1 0 0 1 1 1 0 Prokaryotic N-terminal methylation motif DUF2306 PF10067.4 GAP87777.1 - 1.3 9.1 0.0 1.3 9.1 0.0 3.4 4 0 0 4 4 4 0 Predicted membrane protein (DUF2306) Methyltransf_2 PF00891.13 GAP87778.1 - 5e-36 124.1 0.0 6.7e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 GAP87778.1 - 1.8e-11 44.6 0.1 1.1e-10 42.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP87778.1 - 9.8e-06 25.2 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP87778.1 - 3.7e-05 24.1 0.0 8.8e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP87778.1 - 5.2e-05 23.2 2.5 0.00065 19.7 0.1 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP87778.1 - 6.7e-05 23.2 0.0 0.0002 21.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP87778.1 - 9.5e-05 22.7 0.1 0.00033 20.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAP87778.1 - 0.00017 21.0 0.0 0.00034 20.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 GAP87778.1 - 0.01 15.5 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 GAP87778.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family p450 PF00067.17 GAP87779.1 - 1e-44 152.8 0.0 1.4e-44 152.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MEDS PF14417.1 GAP87779.1 - 0.16 11.0 0.0 0.44 9.5 0.0 1.7 2 0 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain ketoacyl-synt PF00109.21 GAP87780.1 - 1.4e-75 254.0 0.0 3.8e-75 252.6 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 GAP87780.1 - 1.9e-31 108.3 0.3 4e-31 107.3 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 GAP87780.1 - 4.9e-24 85.2 0.0 2e-22 79.9 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 GAP87780.1 - 3.5e-19 69.0 0.0 6.4e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.7 GAP87780.1 - 1.5e-14 54.2 0.0 4.9e-14 52.5 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.20 GAP87780.1 - 6.2e-14 52.0 1.1 1.4e-13 50.8 0.8 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_5 PF12695.2 GAP87780.1 - 2.1e-13 50.2 0.1 1.8e-11 43.9 0.0 3.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Methyltransf_23 PF13489.1 GAP87780.1 - 2.4e-11 43.6 0.0 6.4e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_3 PF07859.8 GAP87780.1 - 2.8e-11 43.4 0.0 8.5e-11 41.8 0.0 1.8 2 0 0 2 2 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAP87780.1 - 1.4e-07 31.6 3.5 1.1e-06 28.6 0.8 2.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAP87780.1 - 1.5e-07 30.9 0.0 0.00032 20.0 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thiolase_N PF00108.18 GAP87780.1 - 7e-06 25.2 0.1 1.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_18 PF12847.2 GAP87780.1 - 0.00014 22.4 0.0 0.00048 20.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain DLH PF01738.13 GAP87780.1 - 0.00017 20.9 0.0 0.69 9.1 0.0 3.4 3 0 0 3 3 3 1 Dienelactone hydrolase family Methyltransf_11 PF08241.7 GAP87780.1 - 0.00026 21.4 0.0 0.0011 19.4 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP87780.1 - 0.00031 21.0 0.0 0.0012 19.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP87780.1 - 0.00095 18.3 0.0 0.0021 17.2 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Abhydrolase_2 PF02230.11 GAP87780.1 - 0.0013 18.2 0.0 0.94 8.8 0.0 2.5 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase ACP_syn_III PF08545.5 GAP87780.1 - 0.0066 16.0 1.5 0.1 12.2 0.1 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III LIP PF03583.9 GAP87780.1 - 0.0088 15.2 0.0 0.02 14.1 0.0 1.5 1 0 0 1 1 1 1 Secretory lipase Thioesterase PF00975.15 GAP87780.1 - 0.0093 16.2 0.1 0.026 14.7 0.0 1.8 2 0 0 2 2 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 GAP87780.1 - 0.017 14.6 0.5 7.2 6.0 0.0 3.2 3 0 0 3 3 3 0 alpha/beta hydrolase fold COesterase PF00135.23 GAP87780.1 - 0.16 10.6 0.0 0.37 9.4 0.0 1.5 1 1 0 1 1 1 0 Carboxylesterase family Methyltransf_28 PF02636.12 GAP87780.1 - 0.16 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase AXE1 PF05448.7 GAP87780.1 - 0.3 9.5 0.0 2.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) SET PF00856.23 GAP87781.1 - 1.5e-08 35.1 0.0 2.8e-07 30.9 0.0 2.5 2 0 0 2 2 2 1 SET domain Ribosomal_L14 PF00238.14 GAP87782.1 - 2.2e-44 150.1 2.3 2.4e-44 149.9 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RNA_POL_M_15KD PF02150.11 GAP87783.1 - 2.1e-11 43.2 3.3 2.1e-11 43.2 2.3 1.8 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit DZR PF12773.2 GAP87783.1 - 0.094 12.5 9.1 0.13 12.1 1.8 2.4 2 0 0 2 2 2 0 Double zinc ribbon GFA PF04828.9 GAP87783.1 - 0.34 10.8 10.9 0.88 9.5 2.2 3.0 2 2 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Dicty_REP PF05086.7 GAP87783.1 - 0.39 8.4 1.6 0.49 8.0 1.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein C1_1 PF00130.17 GAP87783.1 - 1.3 8.7 7.7 0.38 10.5 1.1 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rotamase PF00639.16 GAP87784.1 - 3.5e-21 75.7 0.0 4.2e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 GAP87784.1 - 6.8e-16 58.5 0.0 7.9e-16 58.3 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 GAP87784.1 - 4.9e-06 27.1 0.0 6.1e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain LrgB PF04172.11 GAP87785.1 - 8.2e-18 64.3 8.8 3.1e-11 42.8 0.1 3.4 3 1 0 3 3 3 2 LrgB-like family LrgA PF03788.9 GAP87785.1 - 0.0052 16.4 1.5 0.0052 16.4 1.0 2.3 2 0 0 2 2 2 1 LrgA family NMO PF03060.10 GAP87785.1 - 0.0089 15.2 0.8 0.057 12.5 0.3 2.0 2 0 0 2 2 2 1 Nitronate monooxygenase NicO PF03824.11 GAP87787.1 - 0.055 12.7 0.0 0.061 12.6 0.0 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein DUF1191 PF06697.7 GAP87787.1 - 0.39 9.4 5.7 0.66 8.7 4.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1191) Atrophin-1 PF03154.10 GAP87787.1 - 0.52 8.3 6.0 0.6 8.1 4.1 1.0 1 0 0 1 1 1 0 Atrophin-1 family DUF3129 PF11327.3 GAP87788.1 - 1e-70 237.2 12.5 1.3e-70 236.9 8.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) adh_short PF00106.20 GAP87789.1 - 1.3e-19 70.7 3.1 5.9e-19 68.5 2.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP87789.1 - 4.7e-09 36.1 1.1 7.2e-09 35.5 0.0 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 GAP87789.1 - 1.3e-05 24.8 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAP87789.1 - 0.0012 18.9 0.2 0.013 15.5 0.2 2.2 1 1 0 1 1 1 1 NADH(P)-binding Ank_2 PF12796.2 GAP87790.1 - 3.4e-44 149.0 0.1 2.9e-18 65.9 0.1 3.2 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAP87790.1 - 8e-38 126.3 0.7 2.8e-09 36.3 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat zf-DHHC PF01529.15 GAP87790.1 - 4.7e-35 120.5 8.5 4.7e-35 120.5 5.9 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase Ank_5 PF13857.1 GAP87790.1 - 5.8e-27 93.1 4.9 2.7e-08 33.7 0.0 4.9 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAP87790.1 - 2.4e-25 88.4 4.1 4.3e-08 33.4 0.0 4.0 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP87790.1 - 1.1e-23 80.8 0.5 3.3e-07 29.8 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat SRPRB PF09439.5 GAP87791.1 - 2.7e-25 88.6 0.0 2.2e-15 56.3 0.0 2.9 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 GAP87791.1 - 0.0056 16.6 0.0 0.021 14.8 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAP87791.1 - 0.0083 15.5 0.0 0.077 12.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.16 GAP87791.1 - 0.023 13.9 0.0 0.092 11.9 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_16 PF13191.1 GAP87791.1 - 0.079 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 GAP87791.1 - 0.11 11.6 0.1 0.26 10.4 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAP87791.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 GAP87791.1 - 0.17 10.9 0.1 0.36 9.9 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin PALP PF00291.20 GAP87792.1 - 3.6e-59 200.4 0.2 4.5e-59 200.1 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 GAP87792.1 - 1.6e-09 37.3 0.0 1.3e-08 34.4 0.0 2.4 2 0 0 2 2 2 1 CBS domain CorA PF01544.13 GAP87794.1 - 1e-09 37.8 0.0 2e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Strep_SA_rep PF06696.6 GAP87794.1 - 0.11 12.3 0.1 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Streptococcal surface antigen repeat MARVEL PF01284.18 GAP87795.1 - 4.9e-09 36.1 19.7 1.6e-08 34.4 12.1 2.0 1 1 1 2 2 2 1 Membrane-associating domain Rep_2 PF01719.12 GAP87796.1 - 4.3 6.7 7.5 19 4.6 5.2 2.1 1 1 0 1 1 1 0 Plasmid replication protein F-box PF00646.28 GAP87797.1 - 0.11 12.2 0.1 0.24 11.0 0.1 1.5 1 0 0 1 1 1 0 F-box domain BTB PF00651.26 GAP87798.1 - 0.0003 20.7 0.0 0.0011 18.9 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain PAP2_3 PF14378.1 GAP87799.1 - 1.6e-21 76.7 9.4 1.1e-15 57.7 1.1 2.4 2 0 0 2 2 2 2 PAP2 superfamily PAP2 PF01569.16 GAP87799.1 - 0.0019 17.8 5.0 0.0027 17.3 0.0 2.7 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 GAP87799.1 - 0.13 12.5 0.2 0.13 12.5 0.2 2.9 3 0 0 3 3 3 0 PAP2 superfamily C-terminal Glyco_hydro_28 PF00295.12 GAP87800.1 - 7.1e-81 271.6 10.7 8.1e-81 271.4 7.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 HET PF06985.6 GAP87801.1 - 5e-19 68.8 0.0 9e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-MYND PF01753.13 GAP87801.1 - 0.027 14.3 0.8 0.068 13.0 0.0 2.0 2 0 0 2 2 2 0 MYND finger DUF1771 PF08590.5 GAP87802.1 - 5e-19 68.0 9.9 8.4e-19 67.3 6.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 GAP87802.1 - 2.8e-17 62.6 0.4 6.9e-17 61.4 0.3 1.7 1 0 0 1 1 1 1 Smr domain FTHFS PF01268.14 GAP87802.1 - 0.0014 16.7 0.0 0.0014 16.6 0.0 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase HJURP_C PF12347.3 GAP87802.1 - 0.014 14.9 0.7 0.04 13.4 0.5 1.8 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat CENP-Q PF13094.1 GAP87802.1 - 0.092 12.7 0.6 0.16 12.0 0.4 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3835 PF12927.2 GAP87802.1 - 0.35 11.8 2.0 0.82 10.6 1.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3835) WWbp PF10349.4 GAP87802.1 - 0.81 10.5 10.2 1.8 9.4 7.1 1.7 1 1 0 1 1 1 0 WW-domain ligand protein G-alpha PF00503.15 GAP87803.1 - 3.2e-134 447.4 1.1 3.9e-134 447.1 0.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAP87803.1 - 3.1e-15 55.8 2.0 2.2e-10 40.0 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 GAP87803.1 - 9.6e-05 21.8 0.0 0.00041 19.8 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 GAP87803.1 - 0.0018 18.7 0.7 3.2 8.2 0.0 2.9 2 2 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 GAP87803.1 - 0.0066 15.6 3.1 0.28 10.2 0.0 2.6 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 GAP87803.1 - 0.0098 15.4 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 GAP87803.1 - 0.034 13.5 0.0 1.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MCM PF00493.18 GAP87803.1 - 0.085 11.6 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family MMR_HSR1 PF01926.18 GAP87803.1 - 0.12 12.3 0.0 17 5.3 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 GAP87803.1 - 0.13 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family adh_short PF00106.20 GAP87804.1 - 7.9e-25 87.6 0.1 1.2e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP87804.1 - 1.1e-11 44.7 0.1 2.1e-11 43.8 0.0 1.5 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 GAP87804.1 - 1.9e-06 27.8 0.0 2.5e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAP87804.1 - 2.6e-05 24.3 1.5 0.00014 21.9 1.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 GAP87804.1 - 0.00031 19.8 0.0 0.0005 19.1 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CoA_binding_2 PF13380.1 GAP87804.1 - 0.00087 19.4 0.2 0.0036 17.4 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Eno-Rase_NADH_b PF12242.3 GAP87804.1 - 0.0011 18.6 0.7 0.0037 17.0 0.2 2.0 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase F420_oxidored PF03807.12 GAP87804.1 - 0.0045 17.3 0.0 0.035 14.5 0.1 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 GAP87804.1 - 0.0056 16.3 0.1 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 GAP87804.1 - 0.0083 16.2 0.1 0.016 15.3 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 GAP87804.1 - 0.0099 15.3 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 GAP87804.1 - 0.014 14.5 0.1 0.028 13.5 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 GAP87804.1 - 0.041 13.7 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Polysacc_synt_2 PF02719.10 GAP87804.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sas10 PF09368.5 GAP87805.1 - 9.5e-26 89.7 4.8 9.5e-26 89.7 3.4 2.4 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 GAP87805.1 - 6.1e-10 39.1 0.5 3.1e-09 36.8 0.0 2.4 3 0 0 3 3 3 1 Sas10/Utp3/C1D family V-SNARE PF05008.10 GAP87805.1 - 7.1 6.8 13.9 1.4 9.1 0.9 4.0 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Glyco_hydro_16 PF00722.16 GAP87806.1 - 1e-16 60.7 0.0 1.5e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Fungal_trans PF04082.13 GAP87807.1 - 2.4e-14 52.8 2.4 3.5e-14 52.2 1.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 GAP87807.1 - 3.9e-08 33.1 12.0 1.6e-05 24.9 4.1 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAP87807.1 - 0.00013 22.0 12.4 0.0077 16.4 3.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 GAP87807.1 - 0.0013 18.9 13.7 0.19 12.1 3.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type HET PF06985.6 GAP87808.1 - 0.0024 18.0 0.1 0.0052 16.9 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RasGEF PF00617.14 GAP87809.1 - 5.7e-63 212.0 0.1 1e-62 211.2 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAP87809.1 - 6.3e-28 96.9 0.2 1.6e-27 95.6 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 GAP87809.1 - 5.8e-16 57.6 0.1 1.4e-15 56.4 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAP87809.1 - 3e-14 52.3 0.2 6.3e-14 51.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAP87809.1 - 1.9e-13 49.6 0.1 4.7e-13 48.4 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 GAP87809.1 - 0.00035 20.3 0.4 0.00091 19.0 0.0 2.0 2 0 0 2 2 2 1 WW domain Glyco_hydro_18 PF00704.23 GAP87811.1 - 2.5e-08 33.7 0.0 3.8e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 SH3_1 PF00018.23 GAP87812.1 - 1.6e-05 24.1 0.0 4.2e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAP87812.1 - 0.0047 16.4 0.1 0.017 14.6 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain Glyoxalase_2 PF12681.2 GAP87813.1 - 1e-08 35.7 0.2 1.5e-08 35.1 0.1 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 GAP87813.1 - 0.0019 18.1 0.0 0.0021 18.0 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF2945 PF11160.3 GAP87814.1 - 2.3e-21 75.3 0.3 2.7e-21 75.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2945) Fungal_trans PF04082.13 GAP87815.1 - 3.3e-28 98.2 1.6 5e-28 97.6 1.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP87815.1 - 2.3e-07 30.6 11.8 3.8e-07 29.8 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugarporin_N PF11471.3 GAP87815.1 - 0.054 13.1 0.4 0.15 11.7 0.3 1.7 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension MFS_1 PF07690.11 GAP87816.1 - 1.2e-53 182.1 42.3 1.1e-49 169.1 30.2 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAP87816.1 - 6.3e-15 54.3 19.2 9.4e-15 53.8 13.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAP87816.1 - 4.3e-10 38.7 24.5 4.3e-10 38.7 7.3 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 GAP87816.1 - 2.8e-07 29.2 33.9 3.9e-06 25.5 5.2 2.8 1 1 1 2 2 2 2 MFS/sugar transport protein DUF3716 PF12511.3 GAP87817.1 - 7.3e-17 60.7 8.3 1.4e-16 59.8 5.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) SR-25 PF10500.4 GAP87817.1 - 0.00027 20.5 9.9 0.00044 19.8 6.8 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein PAT1 PF09770.4 GAP87817.1 - 0.0012 17.2 50.9 0.0012 17.2 35.2 1.9 2 0 0 2 2 2 1 Topoisomerase II-associated protein PAT1 SAPS PF04499.10 GAP87817.1 - 0.0033 16.1 11.1 0.0047 15.6 7.7 1.3 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Daxx PF03344.10 GAP87817.1 - 0.039 12.4 23.7 0.049 12.1 16.4 1.1 1 0 0 1 1 1 0 Daxx Family Macoilin PF09726.4 GAP87817.1 - 0.053 11.8 19.4 0.068 11.4 13.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Asp-B-Hydro_N PF05279.6 GAP87817.1 - 0.41 10.4 21.2 0.69 9.7 14.7 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Chorion_2 PF03964.10 GAP87817.1 - 0.8 10.2 15.9 2.4 8.7 11.0 1.8 1 0 0 1 1 1 0 Chorion family 2 SPX PF03105.14 GAP87817.1 - 1.2 8.8 19.5 1.8 8.3 13.5 1.4 1 0 0 1 1 1 0 SPX domain Med15 PF09606.5 GAP87817.1 - 2.6 6.1 82.8 0.013 13.7 50.1 1.8 1 1 1 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal SDA1 PF05285.7 GAP87817.1 - 3.7 6.7 29.5 6.3 5.9 20.5 1.3 1 0 0 1 1 1 0 SDA1 RskA PF10099.4 GAP87817.1 - 4.3 7.0 18.3 0.82 9.3 9.4 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Trp_oprn_chp PF09534.5 GAP87817.1 - 5.1 6.6 9.6 9.6 5.7 6.7 1.4 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1675 PF07897.6 GAP87817.1 - 7.4 6.3 17.3 13 5.5 12.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF4045 PF13254.1 GAP87817.1 - 7.9 5.6 22.0 13 4.9 15.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Hid1 PF12722.2 GAP87817.1 - 10 3.6 28.1 13 3.3 19.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein WD40 PF00400.27 GAP87818.1 - 1.6e-12 46.7 1.1 4.8e-08 32.5 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat HNH_2 PF13391.1 GAP87820.1 - 0.00013 21.6 0.0 0.00029 20.5 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease DUF1264 PF06884.6 GAP87821.1 - 3.5e-54 182.7 0.0 4.5e-54 182.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) p450 PF00067.17 GAP87822.1 - 1.3e-47 162.4 0.0 1.7e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 B2-adapt-app_C PF09066.5 GAP87822.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain p450 PF00067.17 GAP87823.1 - 1.1e-21 76.8 0.0 1.2e-21 76.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 GAP87824.1 - 1.6e-12 47.6 0.2 1.8e-11 44.2 0.0 2.4 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAP87824.1 - 2.1e-05 24.2 0.0 3.9e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 GAP87824.1 - 0.0039 16.6 0.0 0.012 15.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAP87824.1 - 0.097 12.6 0.2 0.48 10.4 0.0 1.9 2 0 0 2 2 2 0 NADH(P)-binding PALP PF00291.20 GAP87824.1 - 0.12 11.5 0.0 0.28 10.3 0.0 1.6 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme DUF3819 PF12842.2 GAP87825.1 - 0.028 14.0 0.0 0.077 12.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) ALIX_LYPXL_bnd PF13949.1 GAP87826.1 - 0.0077 15.2 2.8 0.014 14.4 1.9 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV She9_MDM33 PF05546.6 GAP87826.1 - 2.7 7.4 7.1 3.9 6.9 0.6 2.2 2 0 0 2 2 2 0 She9 / Mdm33 family Sugar_tr PF00083.19 GAP87827.1 - 2.4e-91 306.5 26.4 2.8e-91 306.3 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP87827.1 - 1.1e-34 119.7 23.6 1.1e-34 119.7 16.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Pkinase PF00069.20 GAP87828.1 - 1.5e-06 27.5 0.0 3.4e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 GAP87828.1 - 2.7e-06 27.1 0.5 7.4e-06 25.6 0.1 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 GAP87828.1 - 0.00097 18.9 0.3 0.0016 18.2 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 GAP87828.1 - 0.002 17.2 0.1 0.0034 16.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family NdhN PF11909.3 GAP87828.1 - 0.025 13.9 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 NADH-quinone oxidoreductase cyanobacterial subunit N FtsL PF04999.8 GAP87829.1 - 4.3 7.1 7.1 7.1 6.4 4.9 1.4 1 0 0 1 1 1 0 Cell division protein FtsL Glyco_hydro_92 PF07971.7 GAP87830.1 - 5e-155 516.9 0.1 6e-155 516.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 UPF0114 PF03350.11 GAP87831.1 - 0.28 11.1 6.8 0.04 13.8 1.5 1.9 2 0 0 2 2 2 0 Uncharacterized protein family, UPF0114 UQ_con PF00179.21 GAP87832.1 - 1.4e-05 24.5 0.0 2.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Glyco_hydro_72 PF03198.9 GAP87834.1 - 1.5e-100 336.2 0.1 2.5e-100 335.5 0.1 1.3 2 0 0 2 2 2 1 Glucanosyltransferase Rubella_E2 PF05749.6 GAP87834.1 - 0.0025 17.1 2.0 0.0038 16.5 1.4 1.3 1 0 0 1 1 1 1 Rubella membrane glycoprotein E2 Cellulase PF00150.13 GAP87834.1 - 0.0073 15.5 0.1 0.019 14.1 0.1 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 GAP87834.1 - 0.13 11.1 0.1 0.26 10.1 0.0 1.6 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain WD40 PF00400.27 GAP87835.1 - 2.7e-38 128.4 12.4 7.5e-11 41.4 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.9 GAP87835.1 - 8.8e-32 108.9 15.5 1.7e-31 108.0 10.7 1.5 1 0 0 1 1 1 1 Sof1-like domain PQQ_3 PF13570.1 GAP87835.1 - 0.00061 19.9 0.0 0.23 11.7 0.0 3.7 3 0 0 3 3 3 1 PQQ-like domain DUF3312 PF11768.3 GAP87835.1 - 0.023 12.9 0.0 1.3 7.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3312) adh_short PF00106.20 GAP87836.1 - 1.1e-29 103.4 1.8 1.7e-29 102.8 1.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP87836.1 - 8.9e-14 51.8 0.0 1.2e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP87836.1 - 4.8e-11 42.6 3.5 1.9e-10 40.7 2.5 1.8 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAP87836.1 - 0.0023 17.9 0.1 0.005 16.8 0.1 1.5 2 0 0 2 2 2 1 NADH(P)-binding Pkinase PF00069.20 GAP87837.1 - 2.5e-07 30.1 0.0 3.1e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP87837.1 - 0.00037 19.6 0.0 0.029 13.4 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase PCI PF01399.22 GAP87838.1 - 1.3e-19 70.4 0.6 4e-19 68.8 0.1 2.1 3 0 0 3 3 3 1 PCI domain TPR_8 PF13181.1 GAP87838.1 - 0.00019 20.9 0.2 2.4 8.1 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat DDRGK PF09756.4 GAP87838.1 - 0.0027 17.1 0.2 0.0047 16.3 0.1 1.4 1 0 0 1 1 1 1 DDRGK domain DUF4456 PF14644.1 GAP87838.1 - 0.012 14.8 1.8 0.48 9.6 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4456) PCI_Csn8 PF10075.4 GAP87838.1 - 0.032 13.9 0.1 0.072 12.8 0.1 1.7 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 HTH_Crp_2 PF13545.1 GAP87838.1 - 0.051 13.3 0.3 0.22 11.3 0.1 2.1 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain SAC3_GANP PF03399.11 GAP87838.1 - 0.68 9.4 5.6 3.6 7.0 0.1 2.6 3 0 0 3 3 3 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family TPR_21 PF09976.4 GAP87838.1 - 0.86 9.5 9.9 0.053 13.4 0.3 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAP87838.1 - 0.97 9.4 12.6 1.3 9.0 0.4 4.4 3 1 2 5 5 5 0 Tetratricopeptide repeat DSBA PF01323.15 GAP87841.1 - 1.7e-09 37.5 0.0 1.8e-09 37.4 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain HypD PF01924.11 GAP87841.1 - 0.013 14.2 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase formation hypA family DSBA PF01323.15 GAP87842.1 - 1.3e-13 51.0 2.3 3e-13 49.7 1.1 1.7 2 0 0 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 GAP87842.1 - 0.01 15.8 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Sds3 PF08598.6 GAP87843.1 - 2.6e-47 161.0 7.5 4.2e-47 160.3 5.1 1.5 1 1 0 1 1 1 1 Sds3-like HET PF06985.6 GAP87844.1 - 1.4e-25 90.0 0.3 2.4e-25 89.2 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GATase PF00117.23 GAP87845.1 - 1.6e-11 44.0 0.0 2.1e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 GAP87845.1 - 0.052 12.9 0.0 0.3 10.5 0.0 2.2 1 1 0 1 1 1 0 Peptidase C26 MFS_1 PF07690.11 GAP87846.1 - 3e-34 118.3 37.8 3e-34 118.3 26.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 GAP87846.1 - 0.00074 17.6 0.5 0.00074 17.6 0.3 2.1 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Bestrophin PF01062.16 GAP87846.1 - 0.22 10.4 2.9 0.52 9.2 2.0 1.6 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel DAO PF01266.19 GAP87847.1 - 6.1e-27 94.4 0.0 1.3e-26 93.4 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Formyl_trans_N PF00551.14 GAP87847.1 - 1.9e-14 53.5 0.0 6.4e-14 51.9 0.0 1.8 2 0 0 2 2 2 1 Formyl transferase Pyr_redox PF00070.22 GAP87847.1 - 1.1e-05 25.7 0.0 0.019 15.3 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAP87847.1 - 2.7e-05 23.4 0.0 0.0002 20.5 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 GAP87847.1 - 0.00087 18.3 0.0 0.068 12.0 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 GAP87847.1 - 0.001 17.5 0.1 0.98 7.8 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.1 GAP87847.1 - 0.0018 18.2 0.0 0.0044 17.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAP87847.1 - 0.024 14.5 0.0 0.81 9.5 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 GAP87847.1 - 0.027 14.1 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sugar_tr PF00083.19 GAP87848.1 - 6.1e-111 371.1 14.0 7.3e-111 370.9 9.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP87848.1 - 1.4e-29 102.9 22.2 1.4e-29 102.9 15.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 GAP87850.1 - 6.6e-42 143.4 40.8 6.6e-42 143.4 28.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP87850.1 - 3.5e-12 45.6 12.1 3.5e-12 45.6 8.4 2.7 2 1 0 3 3 3 1 Sugar (and other) transporter GFA PF04828.9 GAP87851.1 - 3.3e-06 26.9 0.4 6.3e-06 26.0 0.3 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 GAP87851.1 - 0.012 14.7 0.0 0.012 14.7 0.0 2.7 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 GAP87851.1 - 0.04 13.3 0.1 0.04 13.3 0.0 2.3 3 0 0 3 3 3 0 zinc-ribbon domain A2L_zn_ribbon PF08792.5 GAP87851.1 - 0.13 11.8 0.1 0.13 11.8 0.0 2.5 3 0 0 3 3 3 0 A2L zinc ribbon domain Cys_rich_CWC PF14375.1 GAP87851.1 - 0.19 11.6 4.9 0.56 10.1 0.3 2.5 3 0 0 3 3 3 0 Cysteine-rich CWC NOB1_Zn_bind PF08772.6 GAP87851.1 - 1.9 8.3 4.9 0.59 9.9 0.2 2.1 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Chorismate_bind PF00425.13 GAP87852.1 - 2.2e-89 299.2 0.0 4.2e-88 294.9 0.0 2.1 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 GAP87852.1 - 4.4e-26 91.5 0.0 2.2e-22 79.5 0.0 3.2 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region NuiA PF07924.6 GAP87853.1 - 0.00033 20.5 0.2 0.029 14.2 0.1 2.1 1 1 0 1 1 1 1 Nuclease A inhibitor-like protein Ribosomal_L3 PF00297.17 GAP87854.1 - 1.6e-116 388.2 7.7 1.9e-116 388.0 5.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 TPR_1 PF00515.23 GAP87855.1 - 7.2e-54 177.3 31.3 3.6e-08 32.6 0.0 10.8 11 1 0 11 11 11 8 Tetratricopeptide repeat TPR_11 PF13414.1 GAP87855.1 - 3.6e-50 167.4 35.7 1e-13 50.7 1.0 6.4 2 2 5 8 8 8 8 TPR repeat TPR_2 PF07719.12 GAP87855.1 - 2.6e-48 158.0 21.1 3.4e-06 26.5 0.0 10.6 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_8 PF13181.1 GAP87855.1 - 3e-40 132.9 20.4 6.6e-06 25.5 0.6 10.3 8 1 2 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.1 GAP87855.1 - 5.2e-34 116.1 13.2 6.8e-08 32.9 0.1 6.6 4 1 3 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.1 GAP87855.1 - 9.4e-30 102.3 23.7 8.2e-07 28.8 0.2 7.1 2 2 4 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 GAP87855.1 - 2.7e-28 95.7 20.6 0.0011 19.0 0.1 10.6 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_14 PF13428.1 GAP87855.1 - 3.3e-27 92.4 13.8 0.0004 20.7 0.0 9.3 3 2 6 9 9 9 8 Tetratricopeptide repeat TPR_19 PF14559.1 GAP87855.1 - 2.6e-25 88.5 15.6 3.5e-05 24.0 0.0 6.7 5 2 2 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.1 GAP87855.1 - 3.6e-24 82.6 11.5 0.0013 18.3 0.0 9.7 9 1 0 9 9 9 6 Tetratricopeptide repeat TPR_6 PF13174.1 GAP87855.1 - 1.5e-23 81.5 17.3 0.002 18.4 0.0 9.8 10 0 0 10 10 10 5 Tetratricopeptide repeat Apc3 PF12895.2 GAP87855.1 - 5.5e-17 61.6 10.0 2.5e-08 33.9 1.1 4.0 4 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 GAP87855.1 - 7.8e-14 51.2 12.1 0.00067 19.4 0.1 7.3 1 1 7 8 8 8 6 Tetratricopeptide repeat TPR_15 PF13429.1 GAP87855.1 - 9.4e-12 44.5 7.5 0.00054 19.1 0.1 5.1 1 1 3 5 5 5 3 Tetratricopeptide repeat TPR_20 PF14561.1 GAP87855.1 - 1.2e-05 25.3 2.9 0.18 11.9 0.0 4.0 3 2 1 4 4 3 2 Tetratricopeptide repeat TPR_21 PF09976.4 GAP87855.1 - 0.0023 17.9 16.1 0.25 11.3 0.0 4.6 4 2 2 6 6 6 3 Tetratricopeptide repeat DUF2225 PF09986.4 GAP87855.1 - 0.0034 16.8 2.7 1.1 8.6 0.0 3.6 2 1 2 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2225) DUF4071 PF13281.1 GAP87855.1 - 0.023 13.5 0.0 0.083 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4071) TPR_10 PF13374.1 GAP87855.1 - 0.027 14.3 19.4 3.3 7.7 0.0 7.2 9 0 0 9 9 7 0 Tetratricopeptide repeat MIT PF04212.13 GAP87855.1 - 0.35 10.7 15.1 3.2 7.7 1.1 5.6 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain GAS PF13851.1 GAP87855.1 - 1.1 8.4 4.2 0.24 10.5 0.1 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding SNAP PF14938.1 GAP87855.1 - 1.3 8.0 15.0 13 4.8 0.2 4.8 1 1 2 4 4 4 0 Soluble NSF attachment protein, SNAP DUF1751 PF08551.5 GAP87856.1 - 1.2e-26 92.9 4.1 2.1e-26 92.1 2.9 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 GAP87856.1 - 0.13 12.2 5.7 0.35 10.8 3.9 1.6 1 1 0 1 1 1 0 Rhomboid family WD40 PF00400.27 GAP87857.1 - 1.4e-14 53.3 2.1 1.1e-06 28.2 0.0 6.4 6 0 0 6 6 6 2 WD domain, G-beta repeat LisH PF08513.6 GAP87857.1 - 4.4e-06 26.2 0.1 9.9e-06 25.1 0.0 1.6 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 GAP87857.1 - 1.7e-05 24.6 0.0 0.55 9.8 0.0 3.6 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Alpha-L-AF_C PF06964.7 GAP87858.1 - 7.3e-38 130.1 0.2 1.1e-37 129.5 0.1 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Reprolysin_5 PF13688.1 GAP87861.1 - 3e-58 196.9 6.2 3e-58 196.9 4.3 3.2 3 1 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 GAP87861.1 - 7.2e-47 159.5 0.7 1.4e-46 158.6 0.5 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 GAP87861.1 - 6.4e-45 153.3 3.6 9e-45 152.8 1.4 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 GAP87861.1 - 5.4e-20 72.1 0.1 5.4e-20 72.1 0.1 2.4 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 GAP87861.1 - 4.9e-18 65.1 32.7 4.9e-18 65.1 22.7 4.9 4 2 1 5 5 5 1 Disintegrin Pep_M12B_propep PF01562.14 GAP87861.1 - 0.00082 19.1 0.1 0.0023 17.7 0.1 1.6 2 0 0 2 2 2 1 Reprolysin family propeptide Reprolysin PF01421.14 GAP87861.1 - 0.0023 17.5 9.3 0.0023 17.5 6.5 3.5 1 1 1 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease AMP-binding PF00501.23 GAP87862.1 - 4.8e-87 292.0 0.0 6.2e-87 291.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAP87862.1 - 5.7e-20 72.0 0.4 1e-18 68.0 0.4 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Rep_fac_C PF08542.6 GAP87863.1 - 4.5e-24 84.2 0.1 1.4e-23 82.6 0.1 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 GAP87863.1 - 3.2e-11 43.1 0.0 6.6e-11 42.1 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 GAP87863.1 - 1.8e-06 28.1 0.1 4.5e-06 26.8 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAP87863.1 - 5.9e-06 26.4 1.6 9e-05 22.6 0.3 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 GAP87863.1 - 0.00078 19.4 1.5 0.035 14.0 0.8 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 GAP87863.1 - 0.0032 17.3 0.1 0.0061 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 GAP87863.1 - 0.012 15.6 0.2 0.33 10.9 0.2 2.4 1 1 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 GAP87863.1 - 0.014 15.7 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_10 PF12846.2 GAP87863.1 - 0.034 13.5 0.2 2.1 7.6 0.0 2.2 1 1 0 2 2 2 0 AAA-like domain SNF2_N PF00176.18 GAP87863.1 - 0.035 12.8 0.1 0.053 12.3 0.1 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Arch_ATPase PF01637.13 GAP87863.1 - 0.038 13.6 0.1 0.12 12.1 0.1 1.7 1 1 0 1 1 1 0 Archaeal ATPase DUF2861 PF11060.3 GAP87863.1 - 0.049 12.9 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2861) T4SS-DNA_transf PF02534.9 GAP87863.1 - 0.052 12.1 0.1 0.15 10.6 0.0 1.7 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer Aminotran_1_2 PF00155.16 GAP87864.1 - 1.2e-33 116.5 0.0 1.4e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II RRM_1 PF00076.17 GAP87865.1 - 2.5e-16 59.0 0.0 4.4e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP87865.1 - 1.9e-11 43.7 0.0 2.9e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP87865.1 - 1.2e-06 28.2 0.0 2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 GAP87865.1 - 0.00067 20.0 2.8 0.00067 20.0 2.0 2.9 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Smg4_UPF3 PF03467.10 GAP87865.1 - 0.096 12.6 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Smg-4/UPF3 family zf-CCCH PF00642.19 GAP87866.1 - 2.2e-06 27.2 7.9 2.9e-06 26.8 0.3 2.7 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C2H2_4 PF13894.1 GAP87867.1 - 0.79 10.2 2.8 27 5.3 0.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Pkinase PF00069.20 GAP87868.1 - 3.8e-70 235.9 1.1 1.1e-69 234.5 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP87868.1 - 2.9e-29 101.9 4.6 4.9e-29 101.1 0.0 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP87868.1 - 5.6e-05 22.2 0.0 0.48 9.3 0.0 3.1 3 0 0 3 3 3 2 Kinase-like Choline_kinase PF01633.15 GAP87868.1 - 0.11 12.0 3.9 10 5.6 2.4 2.4 2 0 0 2 2 2 0 Choline/ethanolamine kinase TFIIA PF03153.8 GAP87868.1 - 0.55 10.0 16.4 0.81 9.5 11.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.9 GAP87868.1 - 0.55 9.9 13.2 0.92 9.1 9.1 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4175 PF13779.1 GAP87868.1 - 0.67 7.5 19.0 0.97 7.0 13.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Activator_LAG-3 PF11498.3 GAP87868.1 - 0.77 8.4 29.9 1.4 7.5 20.7 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DivIC PF04977.10 GAP87868.1 - 9.3 5.8 14.8 20 4.7 10.3 1.5 1 0 0 1 1 1 0 Septum formation initiator CENP-B_dimeris PF09026.5 GAP87869.1 - 0.0092 16.2 5.6 0.0092 16.2 3.9 2.2 3 0 0 3 3 3 1 Centromere protein B dimerisation domain DUF4231 PF14015.1 GAP87869.1 - 0.021 14.7 0.1 4.3 7.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) TRAP_alpha PF03896.11 GAP87869.1 - 0.19 10.7 0.0 0.34 9.8 0.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sporozoite_P67 PF05642.6 GAP87869.1 - 0.2 9.5 0.5 0.3 8.8 0.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BSP_II PF05432.6 GAP87869.1 - 0.68 9.1 13.4 0.015 14.6 3.8 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Nucleoplasmin PF03066.10 GAP87869.1 - 0.79 9.2 7.4 1.7 8.1 5.1 1.5 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 GAP87869.1 - 8.5 5.5 4.8 17 4.5 3.3 1.4 1 0 0 1 1 1 0 NOA36 protein Thi4 PF01946.12 GAP87870.1 - 2.4e-83 278.7 0.1 6.9e-83 277.2 0.1 1.6 1 1 0 1 1 1 1 Thi4 family DAO PF01266.19 GAP87870.1 - 2.7e-07 29.8 2.7 3.9e-07 29.3 0.6 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAP87870.1 - 8.9e-06 24.8 0.4 1.1e-05 24.4 0.3 1.4 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 GAP87870.1 - 2.3e-05 24.3 0.2 6.4e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAP87870.1 - 3.2e-05 23.9 0.4 4.8e-05 23.3 0.2 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP87870.1 - 0.00014 21.9 0.2 0.0002 21.4 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAP87870.1 - 0.00019 21.2 0.1 0.0004 20.2 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 GAP87870.1 - 0.00024 20.3 0.2 0.00036 19.7 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAP87870.1 - 0.00033 19.6 0.9 0.00033 19.6 0.6 2.5 2 1 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 GAP87870.1 - 0.0085 15.1 0.2 0.02 13.9 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 GAP87870.1 - 0.02 13.3 1.0 0.032 12.7 0.3 1.5 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 GAP87870.1 - 0.089 11.6 0.3 0.16 10.8 0.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 GAP87870.1 - 0.1 11.1 0.3 0.15 10.6 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Cutinase PF01083.17 GAP87871.1 - 5.8e-43 146.6 3.1 7.7e-43 146.2 2.1 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 GAP87871.1 - 0.0014 18.1 0.6 0.0027 17.1 0.4 1.6 1 1 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 GAP87871.1 - 0.038 13.7 0.0 0.058 13.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Lipase_3 PF01764.20 GAP87871.1 - 0.078 12.5 0.5 0.15 11.7 0.3 1.6 1 1 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.15 GAP87871.1 - 0.15 11.6 0.4 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold HlyD PF00529.15 GAP87873.1 - 0.088 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 HlyD family secretion protein Kinesin PF00225.18 GAP87874.1 - 6.9e-91 304.4 0.0 6.9e-91 304.4 0.0 3.2 3 0 0 3 3 3 1 Kinesin motor domain ERCC4 PF02732.10 GAP87875.1 - 1.1e-21 77.1 0.1 2.4e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain CAF-1_p150 PF11600.3 GAP87875.1 - 0.0079 15.6 10.2 0.0079 15.6 7.1 1.9 2 1 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Lactamase_B_4 PF13691.1 GAP87875.1 - 0.11 11.9 0.0 0.28 10.6 0.0 1.6 1 0 0 1 1 1 0 tRNase Z endonuclease DUF4246 PF14033.1 GAP87876.1 - 2.5e-145 484.9 0.0 4.5e-145 484.1 0.0 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 GAP87876.1 - 0.041 14.1 0.0 0.082 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DUF3391 PF11871.3 GAP87877.1 - 0.013 15.6 0.0 0.046 13.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DEAD_assoc PF08494.6 GAP87878.1 - 0.081 12.6 0.0 0.081 12.6 0.0 1.1 1 0 0 1 1 1 0 DEAD/H associated Ank_2 PF12796.2 GAP87879.1 - 4e-11 43.1 0.0 0.00014 22.1 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAP87879.1 - 8.9e-10 37.8 0.0 0.3 10.9 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 GAP87879.1 - 1.2e-08 34.8 1.0 0.0084 16.3 0.0 4.3 2 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAP87879.1 - 3.1e-07 30.7 0.0 0.0029 18.0 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP87879.1 - 2.2e-06 27.3 0.0 19 5.9 0.0 5.1 5 0 0 5 5 5 1 Ankyrin repeat Glyco_hydro_61 PF03443.9 GAP87880.1 - 2e-61 207.6 0.2 2.3e-61 207.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PLA2_B PF01735.13 GAP87880.1 - 0.0099 14.0 0.1 0.017 13.3 0.0 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain CSD PF00313.17 GAP87880.1 - 0.091 12.5 0.0 0.25 11.1 0.0 1.7 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain Peptidase_S8 PF00082.17 GAP87881.1 - 1e-15 57.6 0.1 1.8e-15 56.8 0.1 1.4 1 0 0 1 1 1 1 Subtilase family Ank_3 PF13606.1 GAP87881.1 - 0.013 15.6 0.0 0.41 11.0 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.2 GAP87881.1 - 0.013 15.8 0.0 0.34 11.2 0.0 2.6 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.25 GAP87881.1 - 0.024 14.4 0.0 0.082 12.7 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeat Ank_4 PF13637.1 GAP87881.1 - 0.073 13.6 0.0 11 6.6 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAP87883.1 - 2.9e-80 264.6 0.7 4.1e-15 55.9 0.4 9.7 2 2 4 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 GAP87883.1 - 7.3e-56 183.3 6.3 7.1e-05 22.4 0.0 17.0 18 0 0 18 18 18 10 Ankyrin repeat Ank_4 PF13637.1 GAP87883.1 - 3e-50 167.7 7.8 1.2e-06 28.8 0.3 12.2 7 3 3 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP87883.1 - 7.1e-49 158.9 8.0 0.0019 18.2 0.0 18.6 18 1 1 19 19 19 10 Ankyrin repeat Ank_5 PF13857.1 GAP87883.1 - 3e-36 122.6 14.6 1.1e-08 35.0 0.1 13.0 7 4 6 14 14 14 9 Ankyrin repeats (many copies) Pkinase PF00069.20 GAP87883.1 - 3.6e-10 39.4 0.0 7.2e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DUF3447 PF11929.3 GAP87883.1 - 0.0062 16.3 0.0 12 5.7 0.0 5.0 6 0 0 6 6 6 1 Domain of unknown function (DUF3447) Pkinase_Tyr PF07714.12 GAP87883.1 - 0.11 11.5 0.0 0.26 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase RIO1 PF01163.17 GAP87883.1 - 0.18 11.1 0.0 0.37 10.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family SDA1 PF05285.7 GAP87883.1 - 1.1 8.5 7.8 1.7 7.8 5.4 1.2 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.8 GAP87883.1 - 4.2 6.9 9.1 8 6.0 6.3 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Daxx PF03344.10 GAP87883.1 - 5 5.4 11.6 7.3 4.9 8.0 1.1 1 0 0 1 1 1 0 Daxx Family COesterase PF00135.23 GAP87884.1 - 5.8e-77 259.6 0.0 2.8e-70 237.5 0.0 2.0 1 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 GAP87884.1 - 8.5e-09 35.2 0.2 0.0026 17.3 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP87884.1 - 0.0042 16.8 0.2 0.0082 15.9 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAP87884.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Exo_endo_phos PF03372.18 GAP87885.1 - 0.00011 22.2 0.9 0.00016 21.7 0.6 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Mur_ligase_C PF02875.16 GAP87885.1 - 0.083 12.9 0.1 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain DUF3136 PF11334.3 GAP87887.1 - 0.045 13.1 0.2 0.083 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) RasGEF PF00617.14 GAP87888.1 - 1.5e-56 191.0 0.0 4.8e-56 189.4 0.0 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 GAP87888.1 - 7e-19 67.8 0.0 1.8e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 GAP87888.1 - 2.6e-06 26.9 0.0 4.8e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAP87888.1 - 6.2e-05 22.2 0.0 0.00014 21.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAP87888.1 - 0.016 14.7 0.0 0.034 13.6 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain MFS_1 PF07690.11 GAP87889.1 - 2.5e-15 56.0 37.9 7.6e-15 54.4 23.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 GAP87889.1 - 1.8e-10 40.5 9.6 1.8e-10 40.5 6.7 2.9 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 DUF4131 PF13567.1 GAP87889.1 - 0.14 11.5 9.4 9.2 5.6 0.0 4.5 2 1 2 4 4 4 0 Domain of unknown function (DUF4131) DUF3493 PF11998.3 GAP87889.1 - 2 8.3 9.0 0.35 10.8 1.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3493) Pectate_lyase PF03211.8 GAP87890.1 - 6.5e-72 241.4 1.6 7.6e-72 241.1 1.1 1.0 1 0 0 1 1 1 1 Pectate lyase F-box PF00646.28 GAP87893.1 - 0.045 13.4 0.1 0.16 11.7 0.1 1.9 1 0 0 1 1 1 0 F-box domain NUDIX PF00293.23 GAP87894.1 - 2e-09 37.2 0.0 2.7e-09 36.7 0.0 1.3 1 1 0 1 1 1 1 NUDIX domain HET PF06985.6 GAP87895.1 - 1.3e-11 44.7 0.1 2.4e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RelA_SpoT PF04607.12 GAP87896.1 - 2.7e-12 46.7 0.1 9.9e-12 44.8 0.1 2.0 1 1 0 1 1 1 1 Region found in RelA / SpoT proteins VirDNA-topo-I_N PF09266.5 GAP87896.1 - 0.18 11.6 0.9 1.2 9.1 0.0 2.6 3 0 0 3 3 3 0 Viral DNA topoisomerase I, N-terminal HET PF06985.6 GAP87897.1 - 1.1e-17 64.5 0.0 1.8e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 GAP87898.1 - 1.7e-23 83.1 0.0 2.6e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP87898.1 - 2.5e-16 59.5 0.0 4e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 GAP87898.1 - 0.0054 15.5 0.0 0.0087 14.9 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Pectate_lyase_3 PF12708.2 GAP87899.1 - 1.2e-48 166.2 22.0 2.3e-40 139.1 3.0 4.4 3 1 0 3 3 3 2 Pectate lyase superfamily protein Peptidase_S8 PF00082.17 GAP87899.1 - 5.7e-20 71.6 0.7 5.7e-20 71.6 0.5 2.2 2 0 0 2 2 2 1 Subtilase family adh_short PF00106.20 GAP87903.1 - 1.5e-16 60.7 1.8 1.4e-15 57.5 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAP87903.1 - 1e-08 35.0 0.2 2.2e-08 33.9 0.1 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 GAP87903.1 - 6.8e-05 22.4 0.0 0.00021 20.8 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAP87903.1 - 8.7e-05 22.6 0.3 0.0002 21.4 0.2 1.6 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 GAP87903.1 - 0.03 13.2 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 GAP87903.1 - 0.14 11.0 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.15 GAP87903.1 - 0.19 11.6 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.1 GAP87904.1 - 1.6e-10 41.3 0.1 2e-10 41.0 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAP87904.1 - 0.0022 16.9 0.1 0.033 13.1 0.0 2.1 1 1 0 2 2 2 1 Male sterility protein DapB_N PF01113.15 GAP87904.1 - 0.006 16.5 0.0 0.0096 15.8 0.0 1.5 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 GAP87904.1 - 0.01 16.1 0.1 0.021 15.1 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 GAP87904.1 - 0.084 11.5 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DXP_reductoisom PF02670.11 GAP87904.1 - 0.1 13.1 0.4 0.28 11.7 0.1 1.7 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Prominin PF05478.6 GAP87904.1 - 0.19 9.2 0.0 0.27 8.7 0.0 1.1 1 0 0 1 1 1 0 Prominin CBM_4_9 PF02018.12 GAP87906.1 - 0.097 12.6 0.0 0.33 10.9 0.0 1.9 2 1 0 2 2 2 0 Carbohydrate binding domain AcetylCoA_hydro PF02550.10 GAP87907.1 - 4e-50 170.3 0.0 6.5e-50 169.6 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 GAP87907.1 - 1.8e-38 131.6 0.0 2.8e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DUF1992 PF09350.5 GAP87908.1 - 9.7e-25 86.2 0.5 4.9e-24 83.9 0.4 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1992) Pyridoxal_deC PF00282.14 GAP87910.1 - 1.6e-14 53.1 0.0 5.3e-07 28.4 0.0 3.2 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain HET PF06985.6 GAP87911.1 - 4.9e-20 72.1 5.8 2e-17 63.6 0.5 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) NAD_binding_10 PF13460.1 GAP87912.1 - 8.3e-12 45.4 2.8 8.3e-12 45.4 2.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 GAP87912.1 - 5e-10 39.0 0.0 7.6e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 GAP87912.1 - 0.0005 19.5 0.3 0.00086 18.8 0.2 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 GAP87912.1 - 0.00076 18.5 0.1 0.0011 18.0 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 GAP87912.1 - 0.00088 19.1 0.3 0.0015 18.4 0.2 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 GAP87912.1 - 0.0016 18.9 0.3 0.008 16.6 0.2 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 GAP87912.1 - 0.0033 17.7 0.7 0.0062 16.8 0.5 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 GAP87912.1 - 0.14 12.5 1.6 0.3 11.5 1.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF3433 PF11915.3 GAP87913.1 - 1.1e-24 86.3 2.1 6.7e-15 55.0 0.1 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) Tropomyosin_1 PF12718.2 GAP87914.1 - 5e-06 26.4 8.4 5e-06 26.4 5.9 2.6 1 1 1 2 2 2 1 Tropomyosin like DUF1664 PF07889.7 GAP87914.1 - 0.00022 21.0 18.1 0.022 14.5 1.9 3.8 1 1 3 4 4 4 3 Protein of unknown function (DUF1664) IncA PF04156.9 GAP87914.1 - 0.0072 15.9 22.2 0.062 12.8 4.8 2.9 1 1 1 2 2 2 2 IncA protein Baculo_PEP_C PF04513.7 GAP87914.1 - 0.026 14.3 12.7 0.32 10.8 2.6 2.9 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sipho_Gp157 PF05565.6 GAP87914.1 - 0.29 10.7 17.9 0.15 11.6 0.6 3.8 1 1 1 3 3 3 0 Siphovirus Gp157 Fib_alpha PF08702.5 GAP87914.1 - 0.42 10.7 15.1 1.1 9.3 1.8 2.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Reo_sigmaC PF04582.7 GAP87914.1 - 0.43 9.7 7.7 1 8.4 1.3 2.2 1 1 2 3 3 3 0 Reovirus sigma C capsid protein CDC37_N PF03234.9 GAP87914.1 - 0.72 10.1 17.5 0.12 12.7 3.4 2.4 1 1 0 2 2 2 0 Cdc37 N terminal kinase binding AAA_13 PF13166.1 GAP87914.1 - 0.98 7.7 19.4 9.4 4.5 14.0 1.9 1 1 0 1 1 1 0 AAA domain Tropomyosin PF00261.15 GAP87914.1 - 1.8 7.5 29.2 0.56 9.2 14.5 2.9 1 1 0 1 1 1 0 Tropomyosin Matrilin_ccoil PF10393.4 GAP87914.1 - 4.8 6.6 16.0 4.7 6.6 0.4 5.7 6 1 1 7 7 7 0 Trimeric coiled-coil oligomerisation domain of matrilin FadA PF09403.5 GAP87914.1 - 9 6.3 13.9 0.9 9.5 0.7 2.8 2 2 0 2 2 2 0 Adhesion protein FadA SlyX PF04102.7 GAP87914.1 - 9.4 6.6 19.2 8.1 6.9 0.4 5.4 3 2 1 5 5 5 0 SlyX Pectate_lyase PF03211.8 GAP87915.1 - 6.7e-78 260.9 5.3 9e-78 260.5 3.7 1.1 1 0 0 1 1 1 1 Pectate lyase MSP1_C PF07462.6 GAP87915.1 - 0.64 8.3 2.8 0.86 7.9 1.9 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus PIGA PF08288.7 GAP87916.1 - 5.6e-44 148.4 3.1 2.7e-43 146.2 0.5 2.3 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 GAP87916.1 - 3.1e-30 104.8 0.0 5e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 GAP87916.1 - 4e-17 62.5 0.2 7.5e-17 61.6 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 GAP87916.1 - 3.7e-16 59.5 0.0 6.6e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 GAP87916.1 - 4.3e-15 56.1 0.0 8.5e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 GAP87916.1 - 2.3e-06 27.4 0.2 3.8e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 GAP87916.1 - 8.1e-05 22.8 0.0 0.00019 21.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 GAP87916.1 - 0.11 12.0 0.1 0.4 10.1 0.1 2.0 1 1 0 1 1 1 0 Starch synthase catalytic domain DEAD PF00270.24 GAP87917.1 - 4.6e-32 110.8 0.1 1.9e-15 56.7 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP87917.1 - 2.1e-22 78.7 0.0 4.9e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAP87917.1 - 1.3e-05 25.1 0.0 2.8e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Crust_neurohorm PF01147.12 GAP87917.1 - 0.0043 16.3 0.1 0.0077 15.5 0.0 1.4 1 0 0 1 1 1 1 Crustacean CHH/MIH/GIH neurohormone family UvrD-helicase PF00580.16 GAP87917.1 - 0.0043 16.3 0.0 0.0099 15.2 0.0 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain CTP_transf_1 PF01148.15 GAP87918.1 - 2.8e-14 53.4 8.1 1e-13 51.5 3.1 1.8 1 1 1 2 2 2 2 Cytidylyltransferase family KxDL PF10241.4 GAP87919.1 - 1.1e-30 105.3 1.8 1.5e-30 104.9 1.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein Mating_C PF12737.2 GAP87919.1 - 0.00015 20.8 1.4 0.04 12.7 0.0 2.1 2 0 0 2 2 2 2 C-terminal domain of homeodomain 1 XylR_N PF06505.6 GAP87919.1 - 0.06 12.7 0.1 0.091 12.1 0.1 1.2 1 0 0 1 1 1 0 Activator of aromatic catabolism DUF883 PF05957.8 GAP87919.1 - 2.5 8.5 7.9 9.3 6.7 0.5 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Cir_N PF10197.4 GAP87922.1 - 0.0053 16.7 4.3 0.0053 16.7 3.0 4.2 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR Methyltransf_18 PF12847.2 GAP87923.1 - 8.9e-11 42.3 0.0 1.3e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP87923.1 - 2.9e-10 40.0 0.0 4.1e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP87923.1 - 9.8e-10 38.8 0.0 1.7e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP87923.1 - 2.2e-09 37.3 0.0 4.1e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP87923.1 - 5.7e-08 33.1 0.0 8.5e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP87923.1 - 1.5e-07 31.1 0.0 2.3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 GAP87923.1 - 7.1e-06 26.0 0.1 1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_25 PF13649.1 GAP87923.1 - 3.5e-05 24.0 0.0 6.6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 GAP87923.1 - 0.00052 19.5 0.0 0.00073 19.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase DUF427 PF04248.7 GAP87923.1 - 0.00059 19.4 0.1 0.12 12.0 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF427) DUF938 PF06080.7 GAP87923.1 - 0.00076 19.0 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) adh_short_C2 PF13561.1 GAP87923.1 - 0.0018 18.0 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MTS PF05175.9 GAP87923.1 - 0.002 17.5 0.0 0.0036 16.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 GAP87923.1 - 0.0036 16.4 0.0 0.0049 16.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.13 GAP87923.1 - 0.1 11.8 0.0 7.8 5.7 0.0 2.3 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain KR PF08659.5 GAP87923.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 KR domain UPF0146 PF03686.8 GAP87923.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) MetW PF07021.7 GAP87923.1 - 0.14 11.5 0.0 0.25 10.6 0.0 1.4 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW DUF4217 PF13959.1 GAP87924.1 - 3.1e-18 65.0 0.0 5.6e-18 64.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) DEAD PF00270.24 GAP87924.1 - 4.3e-18 65.3 0.0 2.2e-15 56.5 0.0 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP87924.1 - 1.8e-09 37.3 0.0 3.6e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAP87924.1 - 0.0012 18.7 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 GAP87924.1 - 0.015 15.0 0.1 0.073 12.8 0.1 2.1 2 0 0 2 2 2 0 Part of AAA domain CDC45 PF02724.9 GAP87924.1 - 8.2 4.3 7.1 12 3.7 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Band_7 PF01145.20 GAP87925.1 - 3.3e-26 92.3 4.5 5.2e-26 91.6 3.2 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Glyco_hyd_65N_2 PF14498.1 GAP87926.1 - 8.5e-63 212.1 0.0 2.2e-62 210.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, N-terminal domain Amidohydro_1 PF01979.15 GAP87927.1 - 5.1e-21 75.6 0.4 2.6e-11 43.7 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 GAP87927.1 - 5e-12 46.4 9.2 3.4e-11 43.7 6.4 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 GAP87927.1 - 7.3e-11 41.7 0.5 1.2e-09 37.8 0.1 2.6 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_3 PF07969.6 GAP87927.1 - 1.4e-07 31.0 2.5 0.0073 15.5 0.1 3.2 2 1 1 3 3 3 2 Amidohydrolase family Radical_SAM PF04055.16 GAP87927.1 - 0.0068 16.5 0.0 0.088 12.9 0.0 2.1 2 0 0 2 2 2 1 Radical SAM superfamily DUF3918 PF13056.1 GAP87928.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) zf-RING_4 PF14570.1 GAP87930.1 - 0.67 9.5 7.0 5.2 6.7 0.0 3.8 4 0 0 4 4 4 0 RING/Ubox like zinc-binding domain adh_short PF00106.20 GAP87931.1 - 5.6e-26 91.4 0.6 5.6e-26 91.4 0.4 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP87931.1 - 6.3e-20 71.9 0.0 7.9e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAP87931.1 - 0.00031 20.8 0.1 0.00077 19.5 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 GAP87931.1 - 0.032 13.3 0.0 0.043 12.9 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.21 GAP87931.1 - 0.07 12.6 0.1 0.15 11.5 0.1 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NmrA PF05368.8 GAP87931.1 - 0.071 12.3 0.0 0.16 11.1 0.0 1.6 1 0 0 1 1 1 0 NmrA-like family DUF4275 PF14101.1 GAP87932.1 - 0.015 15.3 0.8 0.024 14.6 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4275) NmrA PF05368.8 GAP87934.1 - 2.7e-10 39.8 0.3 2.4e-05 23.7 0.1 2.3 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 GAP87934.1 - 1.2e-08 35.1 5.9 4.4e-08 33.3 4.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 GAP87934.1 - 0.033 14.4 0.9 0.22 11.8 0.0 2.4 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain Ald_Xan_dh_C2 PF02738.13 GAP87935.1 - 5.7e-194 645.4 0.2 8e-194 644.9 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 GAP87935.1 - 4.3e-50 169.4 0.0 8.6e-50 168.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 GAP87935.1 - 1.2e-31 109.0 0.0 2.6e-31 107.9 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 GAP87935.1 - 1.7e-29 101.8 0.0 1.7e-29 101.8 0.0 2.3 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 GAP87935.1 - 8.2e-29 99.3 0.0 1.8e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 GAP87935.1 - 6.9e-08 32.1 1.7 1.5e-07 31.0 0.1 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain PMT PF02366.13 GAP87936.1 - 8e-75 251.3 19.8 8e-75 251.3 13.7 2.7 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 GAP87936.1 - 2.6e-36 124.9 2.0 3.6e-36 124.4 1.4 1.2 1 0 0 1 1 1 1 MIR domain VIT1 PF01988.14 GAP87936.1 - 6.5 6.1 6.4 1.1 8.6 0.7 2.3 2 0 0 2 2 2 0 VIT family Ras PF00071.17 GAP87937.1 - 4.1e-48 162.8 0.0 1.2e-36 125.5 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 GAP87937.1 - 3.8e-15 56.4 0.0 1.3e-14 54.7 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAP87937.1 - 3.6e-08 32.8 0.0 1.2e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAP87937.1 - 6.3e-06 25.7 0.0 1.5e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAP87937.1 - 0.00046 19.3 0.0 0.0011 18.1 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAP87937.1 - 0.00073 19.4 0.0 0.0017 18.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 GAP87937.1 - 0.0048 17.0 0.0 0.011 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 GAP87937.1 - 0.047 13.1 0.0 0.35 10.2 0.0 1.9 1 1 0 2 2 2 0 AAA-like domain PduV-EutP PF10662.4 GAP87937.1 - 0.11 12.0 0.1 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 GAP87937.1 - 0.14 12.1 0.1 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Choline_transpo PF04515.7 GAP87938.1 - 8.8e-13 47.6 19.1 9.1e-12 44.3 12.0 3.2 3 0 0 3 3 3 2 Plasma-membrane choline transporter APH PF01636.18 GAP87941.1 - 9.7e-11 41.8 0.1 3e-10 40.2 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAP87941.1 - 0.00042 19.9 0.0 0.00062 19.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 GAP87941.1 - 0.054 12.1 0.0 0.072 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) WW PF00397.21 GAP87942.1 - 7.4e-08 32.1 5.6 1.4e-07 31.2 3.9 1.5 1 0 0 1 1 1 1 WW domain DUF2012 PF09430.5 GAP87943.1 - 4.3e-23 81.4 0.0 8e-23 80.5 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2012) Cys_Met_Meta_PP PF01053.15 GAP87944.1 - 1.4e-148 494.2 0.0 1.6e-148 494.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 GAP87944.1 - 1.4e-10 40.8 0.4 2.9e-10 39.7 0.2 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 GAP87944.1 - 2.2e-08 33.2 0.1 3.7e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 GAP87944.1 - 8.7e-08 31.4 0.0 1.5e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAP87944.1 - 5.6e-07 28.9 0.0 1.1e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 GAP87944.1 - 0.00016 20.4 0.0 0.00024 19.9 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.6 GAP87944.1 - 0.00092 17.6 0.1 0.0011 17.3 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase MARVEL PF01284.18 GAP87945.1 - 5e-15 55.5 15.3 6.4e-15 55.2 10.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain AMP-binding PF00501.23 GAP87946.1 - 7.2e-78 261.8 0.0 8.9e-78 261.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme WD40 PF00400.27 GAP87947.1 - 6.2e-09 35.3 8.5 0.053 13.4 0.0 5.6 5 1 0 5 5 5 3 WD domain, G-beta repeat Sporozoite_P67 PF05642.6 GAP87947.1 - 0.021 12.7 8.1 0.034 12.0 5.6 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2201_N PF13203.1 GAP87947.1 - 0.11 11.5 11.0 0.041 13.0 0.2 2.5 2 0 0 2 2 2 0 Putative metallopeptidase domain MSP1_C PF07462.6 GAP87947.1 - 5.6 5.2 5.4 9.6 4.4 3.7 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus RRM_1 PF00076.17 GAP87948.1 - 3.7e-07 29.6 0.0 8.3e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP87948.1 - 1.1e-06 28.3 0.0 2.1e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP87948.1 - 0.00014 21.7 0.0 0.00033 20.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 GAP87948.1 - 0.00019 21.6 0.1 0.00066 19.8 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase II-binding domain. Citrate_synt PF00285.16 GAP87949.1 - 9.4e-103 343.6 0.0 1.1e-102 343.3 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 GAP87949.1 - 0.017 14.5 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone Mito_carr PF00153.22 GAP87950.1 - 9.4e-27 92.5 5.7 2.7e-12 46.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein E1-E2_ATPase PF00122.15 GAP87952.1 - 9.4e-65 217.8 7.2 9.4e-65 217.8 5.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 GAP87952.1 - 6.6e-23 82.2 0.0 1.4e-22 81.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAP87952.1 - 3.2e-14 53.5 0.0 8.6e-14 52.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAP87952.1 - 6.6e-10 38.3 0.0 1.5e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 GAP87952.1 - 0.0045 16.5 1.0 0.0078 15.8 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAP87952.1 - 0.093 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit COPI_C PF06957.6 GAP87952.1 - 3.4 6.1 4.4 5.3 5.4 3.1 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Chorion_2 PF03964.10 GAP87953.1 - 0.0039 17.7 1.7 0.015 15.8 1.2 2.0 1 0 0 1 1 1 1 Chorion family 2 DUF3425 PF11905.3 GAP87954.1 - 5.8e-24 84.5 0.2 7.7e-24 84.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 GAP87955.1 - 0.00013 21.8 12.2 0.0023 17.8 6.4 2.2 1 1 1 2 2 2 1 bZIP transcription factor BMFP PF04380.8 GAP87955.1 - 0.071 13.2 1.4 0.071 13.2 1.0 1.9 2 0 0 2 2 2 0 Membrane fusogenic activity COG5 PF10392.4 GAP87955.1 - 0.09 12.7 2.3 0.14 12.0 1.6 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF87 PF01935.12 GAP87955.1 - 0.094 12.5 0.6 0.12 12.1 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 FlaC_arch PF05377.6 GAP87955.1 - 0.17 11.8 0.3 0.58 10.0 0.1 1.8 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF904 PF06005.7 GAP87955.1 - 0.64 10.3 6.2 0.69 10.2 3.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF904) EAP30 PF04157.11 GAP87955.1 - 3 6.9 5.3 4.4 6.4 3.7 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family MerR-DNA-bind PF09278.6 GAP87955.1 - 4.5 7.7 10.7 5.2 7.5 1.9 2.3 1 1 1 2 2 2 0 MerR, DNA binding Metal_resist PF13801.1 GAP87955.1 - 5.7 6.9 11.8 2.7 8.0 5.4 2.3 2 1 0 2 2 2 0 Heavy-metal resistance Nic96 PF04097.9 GAP87956.1 - 9.7e-206 684.5 0.0 1.2e-205 684.2 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.1 GAP87956.1 - 0.0023 18.1 33.2 0.0023 18.1 23.0 3.5 2 1 1 3 3 3 1 Nucleoporin FG repeat region FGGY_C PF02782.11 GAP87957.1 - 3.4e-51 173.7 0.3 4.9e-51 173.1 0.2 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 GAP87957.1 - 3.8e-24 85.3 0.4 9.5e-21 74.2 0.0 2.7 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain VTC PF09359.5 GAP87959.1 - 3.4e-97 324.8 2.4 6.6e-97 323.9 1.7 1.5 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 GAP87959.1 - 7.6e-17 61.9 19.7 2.4e-15 57.0 5.6 4.3 3 1 0 3 3 3 1 SPX domain DUF202 PF02656.10 GAP87959.1 - 5e-09 36.2 1.9 1.3e-08 34.8 1.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Cob_adeno_trans PF01923.13 GAP87959.1 - 0.052 13.3 0.7 5.5 6.7 0.1 2.5 2 0 0 2 2 2 0 Cobalamin adenosyltransferase HNH_2 PF13391.1 GAP87961.1 - 2.6e-13 49.5 0.1 1.4e-11 43.9 0.0 2.4 2 0 0 2 2 2 2 HNH endonuclease Abhydrolase_5 PF12695.2 GAP87962.1 - 6.2e-13 48.7 1.5 9.6e-13 48.1 1.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 GAP87962.1 - 3.3e-11 42.1 0.7 2.1e-09 36.1 0.0 2.8 2 1 1 3 3 3 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.2 GAP87962.1 - 2.1e-06 26.8 0.8 0.00024 20.0 0.0 3.0 3 0 0 3 3 3 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 GAP87962.1 - 0.072 11.8 2.6 0.19 10.4 0.0 2.4 3 0 0 3 3 3 0 Chlorophyllase HAD_2 PF13419.1 GAP87965.1 - 2.9e-29 102.5 0.0 4.6e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Prenyltrans_2 PF13249.1 GAP87965.1 - 0.002 18.4 0.1 1.2 9.5 0.0 2.8 3 0 0 3 3 3 2 Prenyltransferase-like Hydrolase_like PF13242.1 GAP87965.1 - 0.016 14.9 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like DUF2608 PF11019.3 GAP87965.1 - 0.051 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) p450 PF00067.17 GAP87966.1 - 3e-52 177.7 0.0 3.5e-52 177.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 GAP87967.1 - 6.7e-12 45.6 0.0 1.2e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP87967.1 - 1.2e-06 28.3 0.0 5.2e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 GAP87967.1 - 9.5e-05 22.2 0.0 0.00013 21.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAP87967.1 - 0.041 13.8 0.0 0.11 12.4 0.0 1.7 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 GAP87967.1 - 0.07 12.5 0.0 0.094 12.1 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Lactamase_B_2 PF12706.2 GAP87968.1 - 2.1e-33 115.5 0.0 2.6e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAP87968.1 - 7.4e-10 38.7 0.0 1.3e-09 37.9 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 GAP87968.1 - 6.7e-05 22.6 0.0 0.00048 19.8 0.0 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Cation_ATPase_C PF00689.16 GAP87969.1 - 0.018 14.6 4.5 0.021 14.3 3.2 1.1 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus STT3 PF02516.9 GAP87969.1 - 0.052 12.5 7.3 0.056 12.3 5.1 1.1 1 0 0 1 1 1 0 Oligosaccharyl transferase STT3 subunit Virul_fac_BrkB PF03631.10 GAP87969.1 - 0.1 11.9 8.5 0.22 10.8 5.3 1.8 1 1 0 1 1 1 0 Virulence factor BrkB DUF3753 PF12575.3 GAP87969.1 - 5.5 6.8 6.6 2.6 7.8 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) DUF1077 PF06417.7 GAP87971.1 - 0.28 10.5 1.8 0.35 10.2 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1077) ASFV_J13L PF05568.6 GAP87971.1 - 3.6 7.0 5.5 2.3 7.6 0.3 2.1 2 0 0 2 2 2 0 African swine fever virus J13L protein DUF1996 PF09362.5 GAP87972.1 - 4.2e-77 258.9 5.6 5.1e-77 258.6 3.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) p450 PF00067.17 GAP87973.1 - 3.6e-50 170.8 0.0 4.8e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DOMON PF03351.12 GAP87975.1 - 0.00012 21.9 0.0 0.0003 20.6 0.0 1.6 1 0 0 1 1 1 1 DOMON domain ABC_membrane PF00664.18 GAP87976.1 - 3e-69 233.5 37.5 2.3e-37 128.8 8.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAP87976.1 - 1.8e-68 229.0 0.0 4.6e-34 117.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 GAP87976.1 - 1.9e-12 47.7 0.0 0.027 14.4 0.0 4.5 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 GAP87976.1 - 1.7e-11 43.8 5.1 0.0001 21.6 0.0 4.2 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAP87976.1 - 8.4e-10 38.0 0.4 0.00021 20.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 GAP87976.1 - 1.1e-08 34.0 1.0 0.016 13.8 0.0 4.1 4 0 0 4 4 4 2 Predicted ATPase of the ABC class DUF258 PF03193.11 GAP87976.1 - 2.8e-08 33.0 0.0 0.0015 17.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAP87976.1 - 5.1e-08 33.1 0.9 0.039 14.0 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAP87976.1 - 1.9e-06 28.0 1.0 0.045 13.7 0.0 3.5 2 2 1 3 3 3 2 AAA ATPase domain AAA_25 PF13481.1 GAP87976.1 - 5.3e-06 25.9 0.3 0.097 12.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.1 GAP87976.1 - 4.4e-05 23.1 0.3 1.8 8.0 0.0 4.3 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.1 GAP87976.1 - 0.00019 21.8 0.6 0.18 12.1 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 GAP87976.1 - 0.00023 21.9 0.0 0.25 12.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 GAP87976.1 - 0.00033 20.4 0.7 1.2 9.0 0.1 3.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 GAP87976.1 - 0.00066 19.5 0.1 0.24 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.15 GAP87976.1 - 0.00088 18.0 0.0 0.29 9.7 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit MobB PF03205.9 GAP87976.1 - 0.0034 17.0 0.2 1.9 8.2 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.1 GAP87976.1 - 0.0086 15.1 0.0 1.9 7.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 GAP87976.1 - 0.01 15.7 0.1 3.6 7.5 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.1 GAP87976.1 - 0.012 15.5 0.0 16 5.4 0.0 3.7 4 0 0 4 4 4 0 AAA domain AAA_5 PF07728.9 GAP87976.1 - 0.015 15.0 0.3 9 6.0 0.0 3.4 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) SRP54 PF00448.17 GAP87976.1 - 0.023 14.1 0.0 2.7 7.4 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 GAP87976.1 - 0.028 13.4 0.5 8.2 5.4 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin AAA_28 PF13521.1 GAP87976.1 - 0.037 13.9 0.1 0.24 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 GAP87976.1 - 0.05 13.9 0.0 11 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 GAP87976.1 - 0.053 13.7 0.1 4 7.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_10 PF12846.2 GAP87976.1 - 0.088 12.2 3.9 3.2 7.1 0.1 3.3 4 0 0 4 4 4 0 AAA-like domain DUF87 PF01935.12 GAP87976.1 - 0.1 12.4 2.6 3.6 7.3 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF87 NB-ARC PF00931.17 GAP87976.1 - 0.1 11.4 0.3 3.9 6.2 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain KaiC PF06745.8 GAP87976.1 - 0.14 11.2 1.5 1.2 8.1 0.1 2.3 2 0 0 2 2 2 0 KaiC Rad17 PF03215.10 GAP87976.1 - 0.39 9.3 0.0 0.84 8.2 0.0 1.4 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Fungal_trans PF04082.13 GAP87977.1 - 1.6e-14 53.4 0.2 4.3e-14 52.0 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain AMP-binding PF00501.23 GAP87978.1 - 7.4e-84 281.5 0.2 9.3e-84 281.2 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAP87978.1 - 6.5e-13 49.4 0.1 2.3e-12 47.6 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SH3_3 PF08239.6 GAP87978.1 - 0.029 14.5 0.1 4.7 7.4 0.0 2.5 2 0 0 2 2 2 0 Bacterial SH3 domain Molydop_binding PF01568.16 GAP87978.1 - 0.09 12.5 0.0 0.23 11.3 0.0 1.6 1 1 0 1 1 1 0 Molydopterin dinucleotide binding domain DUF2225 PF09986.4 GAP87978.1 - 0.099 12.0 0.1 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) F-box-like PF12937.2 GAP87979.1 - 2.4e-07 30.3 1.1 4.9e-07 29.3 0.8 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAP87979.1 - 2.1e-06 27.2 3.1 4.6e-06 26.1 2.1 1.6 1 0 0 1 1 1 1 F-box domain Fungal_trans PF04082.13 GAP87980.1 - 4.2e-13 48.7 0.1 9e-13 47.6 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP87980.1 - 5.1e-09 35.9 13.0 9.7e-09 34.9 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NADH-u_ox-rdase PF10785.4 GAP87981.1 - 3e-33 113.9 0.8 5.6e-33 113.0 0.5 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 GAP87981.1 - 1.6e-31 107.8 0.0 2.6e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Swi3 PF07962.7 GAP87982.1 - 1.1e-29 101.8 0.2 2.5e-29 100.7 0.1 1.6 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 DTHCT PF08070.6 GAP87982.1 - 0.27 11.8 8.2 0.64 10.7 0.4 3.1 2 1 0 2 2 2 0 DTHCT (NUC029) region Cwf_Cwc_15 PF04889.7 GAP87982.1 - 3.7 7.1 10.6 0.15 11.7 2.8 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DSHCT PF08148.7 GAP87983.1 - 3.2e-62 208.9 0.7 5.9e-62 208.0 0.5 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 GAP87983.1 - 4.4e-20 71.8 0.0 1e-19 70.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP87983.1 - 6.8e-06 25.8 1.0 1.5e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 GAP87983.1 - 0.00076 18.7 3.7 0.1 11.7 0.3 2.5 2 0 0 2 2 2 2 rRNA-processing arch domain ResIII PF04851.10 GAP87983.1 - 0.018 14.8 0.1 0.29 10.9 0.0 2.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1996 PF09362.5 GAP87984.1 - 3.2e-87 292.0 3.4 3.9e-87 291.8 2.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) FA_desaturase PF00487.19 GAP87985.1 - 0.027 13.9 0.3 0.029 13.7 0.2 1.1 1 0 0 1 1 1 0 Fatty acid desaturase DUF4131 PF13567.1 GAP87985.1 - 0.059 12.7 0.8 0.064 12.6 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Snf7 PF03357.16 GAP87987.1 - 1.3e-08 34.4 25.8 1.3e-08 34.4 17.9 1.5 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.9 GAP87987.1 - 0.0063 15.9 7.2 0.03 13.7 5.0 1.9 1 1 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway SATase_N PF06426.9 GAP87987.1 - 0.66 10.2 6.6 1 9.6 2.9 2.3 1 1 1 2 2 2 0 Serine acetyltransferase, N-terminal Lipoprotein_Ltp PF07553.6 GAP87987.1 - 0.68 9.8 4.2 25 4.8 1.3 2.8 2 1 0 2 2 2 0 Host cell surface-exposed lipoprotein ASL_C PF08328.6 GAP87987.1 - 0.9 9.4 6.5 0.54 10.1 2.0 2.1 1 1 0 2 2 2 0 Adenylosuccinate lyase C-terminal DUF1451 PF07295.6 GAP87987.1 - 4.1 7.1 11.8 0.69 9.6 3.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) bZIP_2 PF07716.10 GAP87989.1 - 8.5e-06 25.5 22.1 5.9e-05 22.8 15.3 2.2 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 GAP87989.1 - 4.7e-05 23.2 16.8 8.7e-05 22.3 11.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 GAP87989.1 - 0.034 14.4 12.5 0.068 13.4 8.6 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor ADIP PF11559.3 GAP87989.1 - 0.44 10.4 9.8 0.84 9.5 6.8 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 GAP87989.1 - 0.64 9.5 4.9 1.2 8.7 3.4 1.4 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 GAP87989.1 - 0.79 8.7 4.5 1.1 8.1 3.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Secretin_N_2 PF07655.8 GAP87990.1 - 0.036 14.4 2.1 0.036 14.4 1.5 2.7 3 0 0 3 3 3 0 Secretin N-terminal domain DUF1183 PF06682.7 GAP87990.1 - 0.06 12.9 11.9 0.081 12.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) Peptidase_M24 PF00557.19 GAP87992.1 - 1.6e-45 155.2 0.1 2e-45 154.9 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Reprolysin_3 PF13582.1 GAP87992.1 - 0.053 14.0 0.2 0.44 11.0 0.0 2.1 1 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Ank_2 PF12796.2 GAP87993.1 - 2e-35 120.9 8.9 1.4e-09 38.1 0.2 5.3 2 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAP87993.1 - 4.5e-28 97.0 5.7 5.6e-08 33.0 0.0 7.6 5 1 4 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.25 GAP87993.1 - 1.4e-27 94.1 13.9 0.00033 20.3 0.0 10.8 11 0 0 11 11 11 7 Ankyrin repeat Ank_3 PF13606.1 GAP87993.1 - 4.5e-18 63.5 8.5 0.079 13.2 0.0 10.0 11 0 0 11 11 11 4 Ankyrin repeat Ank_5 PF13857.1 GAP87993.1 - 3.1e-14 52.6 9.9 0.18 12.1 0.0 8.3 5 2 3 9 9 9 5 Ankyrin repeats (many copies) DUF3447 PF11929.3 GAP87993.1 - 0.00039 20.1 0.0 2.2 8.1 0.0 4.2 2 2 1 4 4 4 2 Domain of unknown function (DUF3447) Glyco_hydro_61 PF03443.9 GAP87995.1 - 1.4e-51 175.3 1.1 1.7e-51 175.0 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 HpaB PF03241.8 GAP87995.1 - 0.086 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal FTA2 PF13095.1 GAP87996.1 - 1.7e-25 89.9 0.0 2.2e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Sugar_tr PF00083.19 GAP87997.1 - 1.2e-78 264.6 22.6 1.4e-78 264.5 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP87997.1 - 2.1e-20 72.7 31.9 2.3e-15 56.2 3.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 GAP87997.1 - 0.0018 18.2 10.4 0.35 10.9 0.2 3.9 3 1 0 3 3 3 2 Protein of unknown function (DUF1228) CTP-dep_RFKase PF01982.11 GAP87998.1 - 0.078 12.6 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF120 Arylesterase PF01731.15 GAP87998.1 - 0.12 12.3 0.0 0.45 10.5 0.0 2.0 2 0 0 2 2 2 0 Arylesterase Hce2 PF14856.1 GAP87999.1 - 3.8e-09 36.3 0.0 1.7e-08 34.2 0.0 1.9 1 1 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor p450 PF00067.17 GAP88002.1 - 3.4e-74 250.0 0.0 4.1e-74 249.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Phage_G PF02306.10 GAP88003.1 - 0.012 15.2 0.4 0.018 14.6 0.3 1.2 1 0 0 1 1 1 0 Major spike protein (G protein) Podoplanin PF05808.6 GAP88003.1 - 0.039 13.5 2.0 0.045 13.3 0.7 1.6 1 1 1 2 2 2 0 Podoplanin Lamp PF01299.12 GAP88003.1 - 0.048 12.7 0.5 0.048 12.7 0.3 2.0 3 0 0 3 3 3 0 Lysosome-associated membrane glycoprotein (Lamp) DAP10 PF07213.6 GAP88003.1 - 0.051 13.3 0.5 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 DAP10 membrane protein EphA2_TM PF14575.1 GAP88003.1 - 0.08 13.3 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LRR19-TM PF15176.1 GAP88003.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain VSP PF03302.8 GAP88003.1 - 0.16 10.5 0.7 0.24 9.9 0.5 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF2648 PF10855.3 GAP88003.1 - 0.18 11.2 0.0 0.54 9.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2648) MtrF PF09472.5 GAP88003.1 - 3.8 6.8 5.9 7.2 5.9 4.1 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Mucin PF01456.12 GAP88004.1 - 0.004 16.9 21.6 0.0071 16.1 14.9 1.5 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF4215 PF13948.1 GAP88004.1 - 0.061 13.5 1.5 0.1 12.8 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4215) DUF1180 PF06679.7 GAP88004.1 - 0.62 9.9 4.3 1.1 9.1 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Pol_alpha_B_N PF08418.5 GAP88004.1 - 2.5 7.5 7.2 3.4 7.1 5.0 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Hamartin PF04388.7 GAP88004.1 - 3 6.3 6.5 3.2 6.2 4.5 1.2 1 0 0 1 1 1 0 Hamartin protein Sterol_MT_C PF08498.5 GAP88006.1 - 6.1e-28 96.5 0.1 9.8e-28 95.9 0.1 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 GAP88006.1 - 1e-21 77.2 0.0 1.9e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP88006.1 - 3.9e-18 65.4 0.0 5.8e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP88006.1 - 1.4e-13 50.9 0.0 2.2e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP88006.1 - 1e-12 48.2 0.0 2.4e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP88006.1 - 1.2e-11 44.1 0.0 2.3e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 GAP88006.1 - 3.3e-11 42.7 0.0 4.5e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 GAP88006.1 - 3.6e-11 43.6 0.0 1e-10 42.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP88006.1 - 6.5e-11 42.5 0.0 1.5e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP88006.1 - 3.2e-09 36.8 0.0 1e-08 35.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 GAP88006.1 - 5.3e-05 22.8 0.0 8.3e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.14 GAP88006.1 - 0.00014 21.4 0.0 0.00022 20.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 GAP88006.1 - 0.00016 21.0 0.0 0.00034 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 GAP88006.1 - 0.00026 20.2 0.0 0.00098 18.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 GAP88006.1 - 0.00091 18.6 0.0 0.0037 16.6 0.0 1.9 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.11 GAP88006.1 - 0.0055 15.0 0.0 0.0076 14.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 GAP88006.1 - 0.007 15.4 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.13 GAP88006.1 - 0.026 13.7 0.1 0.054 12.6 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase Methyltransf_32 PF13679.1 GAP88006.1 - 0.049 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Transket_pyr PF02779.19 GAP88007.1 - 9.2e-47 158.8 0.0 1.3e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 GAP88007.1 - 3.9e-37 126.9 0.0 1.2e-36 125.3 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain UPF0228 PF05727.6 GAP88007.1 - 0.14 11.9 0.1 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0228) Asp PF00026.18 GAP88009.1 - 2.4e-64 217.6 4.8 3e-64 217.2 3.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAP88009.1 - 7.7e-07 29.2 0.0 3.1e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Aminotran_5 PF00266.14 GAP88010.1 - 1.1e-28 100.0 0.0 8.8e-20 70.7 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V p450 PF00067.17 GAP88012.1 - 7e-55 186.3 0.0 8.9e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pex16 PF08610.5 GAP88013.1 - 5.3e-103 344.5 1.4 6e-103 344.3 1.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Nucleos_tra2_N PF01773.15 GAP88013.1 - 0.13 12.6 1.0 3.6 8.0 0.3 2.3 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter N-terminus NUDIX PF00293.23 GAP88014.1 - 1.5e-08 34.3 0.1 2.2e-08 33.8 0.1 1.3 1 1 0 1 1 1 1 NUDIX domain SWIRM PF04433.12 GAP88015.1 - 1.9e-15 56.7 0.1 1.5e-14 53.8 0.0 2.0 2 0 0 2 2 2 1 SWIRM domain Terpene_synth_C PF03936.11 GAP88016.1 - 2e-16 60.0 1.2 3e-16 59.4 0.8 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Rubi_NSP_C PF12601.3 GAP88016.1 - 0.0015 18.4 0.1 0.13 12.2 0.0 2.8 3 0 0 3 3 3 1 Rubivirus non-structural protein Abhydrolase_6 PF12697.2 GAP88017.1 - 1.1e-05 25.4 0.1 3.4e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family NACHT PF05729.7 GAP88017.1 - 0.00098 18.8 0.0 0.007 16.0 0.0 2.3 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 GAP88017.1 - 0.0056 16.6 0.0 0.032 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.1 GAP88017.1 - 0.0082 15.7 0.1 0.023 14.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain DUF676 PF05057.9 GAP88017.1 - 0.017 14.4 0.0 0.069 12.4 0.0 1.9 2 0 0 2 2 2 0 Putative serine esterase (DUF676) NB-ARC PF00931.17 GAP88017.1 - 0.019 13.8 0.0 0.051 12.4 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.1 GAP88017.1 - 0.037 14.1 0.0 0.17 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 GAP88017.1 - 0.05 13.1 0.1 0.14 11.6 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 GAP88017.1 - 0.14 12.2 0.2 0.43 10.7 0.1 1.8 1 0 0 1 1 1 0 RNA helicase Beta-lactamase PF00144.19 GAP88018.1 - 8.5e-36 123.6 0.5 1.4e-35 122.9 0.3 1.2 1 0 0 1 1 1 1 Beta-lactamase Zn_clus PF00172.13 GAP88018.1 - 0.0025 17.6 6.0 0.0056 16.5 4.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAP88018.1 - 0.18 10.3 0.0 0.28 9.7 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Glyco_transf_90 PF05686.7 GAP88019.1 - 3.4e-10 39.1 0.1 1.1e-09 37.4 0.1 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 90 Glypican PF01153.14 GAP88021.1 - 0.23 10.0 0.2 0.33 9.5 0.1 1.1 1 0 0 1 1 1 0 Glypican Lipase_GDSL PF00657.17 GAP88023.1 - 1.4e-18 67.6 0.0 1.7e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Plant_tran PF04827.9 GAP88023.1 - 0.055 12.8 0.1 0.092 12.1 0.1 1.3 1 0 0 1 1 1 0 Plant transposon protein zf-C2H2_jaz PF12171.3 GAP88024.1 - 1.2e-06 28.5 2.6 1.9e-06 27.8 1.8 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAP88024.1 - 0.00045 20.3 0.5 0.00072 19.6 0.4 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 GAP88024.1 - 0.013 15.7 0.1 0.025 14.9 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 GAP88024.1 - 0.032 14.5 0.8 0.056 13.8 0.6 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 GAP88024.1 - 0.056 13.5 0.3 0.082 13.0 0.2 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF1691 PF07950.6 GAP88025.1 - 3.8e-40 136.2 3.5 5e-24 84.3 0.8 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1691) Sulfotransfer_3 PF13469.1 GAP88026.1 - 7.7e-06 26.9 0.1 9.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family CPT PF07931.7 GAP88026.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Sulfotransfer_1 PF00685.22 GAP88026.1 - 0.14 11.3 0.0 0.41 9.8 0.0 1.9 1 1 0 1 1 1 0 Sulfotransferase domain CFEM PF05730.6 GAP88028.1 - 2.2e-13 49.8 11.4 4.8e-13 48.7 7.9 1.6 1 0 0 1 1 1 1 CFEM domain p450 PF00067.17 GAP88029.1 - 1.2e-68 231.7 0.0 1.6e-68 231.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AATase PF07247.7 GAP88030.1 - 0.0004 19.0 0.0 0.0084 14.7 0.0 2.0 1 1 0 1 1 1 1 Alcohol acetyltransferase Pro-kuma_activ PF09286.6 GAP88031.1 - 1.3e-46 158.2 0.1 2.4e-46 157.3 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 GAP88031.1 - 1.5e-06 27.5 1.9 3.5e-06 26.3 1.3 1.6 1 0 0 1 1 1 1 Subtilase family peroxidase PF00141.18 GAP88032.1 - 2.2e-90 302.1 0.0 6e-47 160.0 0.0 2.4 2 1 0 2 2 2 2 Peroxidase MFS_1 PF07690.11 GAP88033.1 - 3.6e-26 91.7 35.0 3.6e-26 91.7 24.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Methyltrn_RNA_3 PF02598.12 GAP88034.1 - 2.1e-71 240.6 0.0 2.6e-71 240.3 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase Thioredoxin PF00085.15 GAP88035.1 - 6.1e-27 93.3 0.0 7.9e-27 92.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 GAP88035.1 - 1.5e-06 28.1 0.0 3.4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 GAP88035.1 - 1.4e-05 25.2 0.1 5.4e-05 23.3 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 GAP88035.1 - 0.00087 19.2 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 GAP88035.1 - 0.016 14.8 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family Phosducin PF02114.11 GAP88035.1 - 0.024 13.3 0.0 0.034 12.8 0.0 1.1 1 0 0 1 1 1 0 Phosducin Redoxin PF08534.5 GAP88035.1 - 0.025 14.1 0.1 0.067 12.7 0.1 1.6 1 1 1 2 2 2 0 Redoxin Ank_2 PF12796.2 GAP88036.1 - 1.6e-37 127.6 3.6 1.7e-14 53.9 0.0 4.6 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAP88036.1 - 6.5e-37 123.5 0.1 1.9e-07 30.5 0.0 6.8 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 GAP88036.1 - 3.5e-30 103.3 0.5 7e-08 32.4 0.0 5.6 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP88036.1 - 8e-28 93.7 0.1 3.2e-05 23.7 0.0 7.7 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 GAP88036.1 - 4.2e-27 94.0 0.2 7.4e-08 32.7 0.0 5.6 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Sugar_tr PF00083.19 GAP88037.1 - 6.7e-59 199.6 13.6 1.2e-58 198.8 9.4 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP88037.1 - 5.2e-08 31.9 41.0 5.6e-05 22.0 11.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Rsm22 PF09243.5 GAP88038.1 - 6.9e-30 104.0 0.0 7.7e-29 100.5 0.0 2.5 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_18 PF12847.2 GAP88038.1 - 0.038 14.5 0.1 0.37 11.3 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 GAP88038.1 - 0.042 14.3 0.0 0.23 11.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain TP_methylase PF00590.15 GAP88039.1 - 7e-45 153.3 0.3 1.3e-44 152.4 0.2 1.5 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 GAP88039.1 - 5.7e-12 45.7 0.0 1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 GAP88039.1 - 9.5e-11 40.8 0.0 2.2e-07 30.1 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 GAP88039.1 - 2.2e-06 26.5 0.0 5.4e-06 25.2 0.0 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central DUF1820 PF08850.6 GAP88040.1 - 0.074 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1820) FAD_binding_3 PF01494.14 GAP88041.1 - 2.2e-17 63.1 0.3 8.8e-17 61.1 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAP88041.1 - 7.1e-13 48.1 0.7 2.1e-05 23.6 0.3 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAP88041.1 - 4.4e-07 29.1 0.2 7.6e-07 28.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAP88041.1 - 9.2e-07 28.7 0.4 2.1e-06 27.6 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAP88041.1 - 1.2e-06 28.5 0.9 7.7e-06 25.9 0.6 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAP88041.1 - 1.5e-06 26.9 0.2 0.015 13.7 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.22 GAP88041.1 - 2.6e-06 27.7 0.1 0.0036 17.6 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAP88041.1 - 5e-05 22.5 1.3 0.0002 20.5 0.9 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAP88041.1 - 0.00012 21.0 0.1 0.17 10.7 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.17 GAP88041.1 - 0.00027 19.9 0.2 0.00067 18.6 0.1 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 GAP88041.1 - 0.0019 18.2 0.2 0.0082 16.2 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAP88041.1 - 0.008 15.9 0.3 0.35 10.6 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 GAP88041.1 - 0.018 13.7 0.1 0.16 10.5 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.16 GAP88041.1 - 0.15 11.6 0.0 2.6 7.6 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NACHT PF05729.7 GAP88042.1 - 2.7e-09 36.9 0.5 7.3e-09 35.4 0.1 2.0 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 GAP88042.1 - 0.014 15.5 0.7 0.077 13.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 GAP88042.1 - 0.015 15.2 6.2 0.025 14.5 0.0 3.5 2 1 1 3 3 3 0 AAA ATPase domain Strabismus PF06638.6 GAP88042.1 - 0.023 13.0 0.9 0.048 11.9 0.7 1.4 1 0 0 1 1 1 0 Strabismus protein UvrD-helicase PF00580.16 GAP88042.1 - 1.8 7.7 6.1 7.3 5.7 0.1 3.1 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain NUDIX PF00293.23 GAP88043.1 - 2.6e-18 65.9 0.4 3.6e-18 65.5 0.3 1.2 1 0 0 1 1 1 1 NUDIX domain Radical_SAM PF04055.16 GAP88044.1 - 0.0001 22.5 0.1 0.002 18.3 0.1 2.3 1 1 1 2 2 2 2 Radical SAM superfamily DUF676 PF05057.9 GAP88045.1 - 1.9e-05 24.0 0.0 3.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 GAP88045.1 - 0.079 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.2 GAP88045.1 - 0.1 12.4 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP88047.1 - 1.3e-17 63.9 4.2 2.3e-17 63.1 2.9 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 GAP88047.1 - 7.2e-05 22.3 0.0 0.0011 18.4 0.0 2.2 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 GAP88047.1 - 8.2e-05 22.5 19.4 0.0007 19.5 12.4 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 GAP88047.1 - 0.00044 18.6 0.0 0.011 14.0 0.0 2.1 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.2 GAP88047.1 - 0.00087 18.2 0.0 0.0014 17.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.16 GAP88047.1 - 0.0021 17.3 0.0 0.0081 15.3 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 GAP88047.1 - 0.012 14.8 4.2 0.03 13.5 2.9 1.6 1 1 0 1 1 1 0 Esterase PHB depolymerase DLH PF01738.13 GAP88047.1 - 0.018 14.3 0.0 0.065 12.5 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family Esterase PF00756.15 GAP88047.1 - 0.02 14.3 0.1 0.043 13.2 0.1 1.6 1 1 0 1 1 1 0 Putative esterase Chlorophyllase PF07224.6 GAP88047.1 - 0.026 13.3 0.0 0.057 12.2 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase PGAP1 PF07819.8 GAP88047.1 - 0.044 13.3 0.0 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 GAP88047.1 - 0.1 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2048 PF09752.4 GAP88047.1 - 0.18 10.6 0.7 0.66 8.7 0.1 2.2 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2048) HD PF01966.17 GAP88048.1 - 0.0021 18.0 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 HD domain HMG_box PF00505.14 GAP88049.1 - 1.7e-11 44.1 0.0 1.7e-11 44.1 0.0 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 GAP88049.1 - 0.0019 18.5 0.0 0.0039 17.5 0.0 1.6 1 0 0 1 1 1 1 HMG-box domain Dynamin_N PF00350.18 GAP88050.1 - 2.5e-14 53.4 0.5 6.1e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 GAP88050.1 - 6.3e-06 26.1 0.0 0.0046 16.9 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 GAP88050.1 - 1.6e-05 24.1 0.0 0.0002 20.5 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 GAP88050.1 - 0.00017 21.9 0.0 0.00069 19.9 0.0 2.2 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 GAP88050.1 - 0.0029 17.6 3.3 0.0043 17.0 0.0 3.0 4 0 0 4 4 4 1 AAA ATPase domain ApoLp-III PF07464.6 GAP88050.1 - 0.0058 16.6 0.2 0.029 14.3 0.2 2.3 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) AAA_29 PF13555.1 GAP88050.1 - 0.032 13.7 0.0 0.078 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 GAP88050.1 - 0.036 13.4 0.5 0.29 10.5 0.0 2.6 3 0 0 3 3 3 0 AAA-like domain AAA_23 PF13476.1 GAP88050.1 - 3.2 8.0 0.0 3.2 8.0 0.0 3.5 3 1 0 3 3 3 0 AAA domain Spectrin PF00435.16 GAP88050.1 - 6.3 7.1 10.8 0.38 11.0 0.3 3.9 4 1 1 5 5 5 0 Spectrin repeat DUF1772 PF08592.6 GAP88052.1 - 0.0021 17.7 0.6 0.0033 17.1 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Jacalin PF01419.12 GAP88055.1 - 0.21 11.4 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 Jacalin-like lectin domain Clr5 PF14420.1 GAP88056.1 - 5.7e-20 70.9 2.5 9e-20 70.3 1.0 2.0 2 0 0 2 2 2 1 Clr5 domain Prp19_bind PF06991.6 GAP88058.1 - 0.1 11.8 0.1 0.13 11.5 0.1 1.3 1 1 0 1 1 1 0 Splicing factor, Prp19-binding domain CENP-B_dimeris PF09026.5 GAP88058.1 - 3.4 7.9 5.7 4.7 7.5 3.8 1.6 1 1 0 1 1 1 0 Centromere protein B dimerisation domain Peptidase_C1_2 PF03051.10 GAP88059.1 - 1.5e-133 445.5 0.0 1.1e-66 225.1 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.18 GAP88059.1 - 1.9e-06 27.9 0.1 0.019 14.8 0.1 2.3 2 0 0 2 2 2 2 Papain family cysteine protease eIF-5a PF01287.15 GAP88060.1 - 3.2e-05 23.7 0.0 7.5e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold DUF3441 PF11923.3 GAP88061.1 - 7.5e-33 112.5 0.0 2.7e-32 110.6 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3441) FbpA PF05833.6 GAP88061.1 - 3.6e-30 104.9 4.0 3.6e-30 104.9 2.7 2.8 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 GAP88061.1 - 9.6e-23 79.8 0.0 3e-22 78.3 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Herpes_TAF50 PF03326.8 GAP88061.1 - 0.25 10.2 11.5 0.4 9.5 8.0 1.2 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Trypan_PARP PF05887.6 GAP88062.1 - 0.0077 16.0 8.4 0.0077 16.0 5.8 2.0 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) Ank_5 PF13857.1 GAP88063.1 - 1.4e-07 31.5 0.0 5e-07 29.7 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAP88063.1 - 0.004 17.4 0.0 0.0094 16.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAP88063.1 - 0.022 14.5 0.1 0.07 12.9 0.1 1.9 1 0 0 1 1 1 0 Ankyrin repeat zf-C2H2_3 PF13878.1 GAP88063.1 - 0.11 12.1 1.1 0.27 10.8 0.0 2.1 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-C2H2_4 PF13894.1 GAP88063.1 - 1.2 9.6 3.0 0.72 10.3 0.3 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger CFEM PF05730.6 GAP88064.1 - 0.00015 21.4 2.3 0.00015 21.4 1.6 2.2 2 0 0 2 2 2 1 CFEM domain Myosin_head PF00063.16 GAP88066.1 - 7.8e-246 817.4 0.0 7.8e-246 817.4 0.0 3.3 5 0 0 5 5 5 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 GAP88066.1 - 4.2e-33 114.1 136.1 1.8e-25 88.8 51.6 7.1 2 2 4 7 7 7 6 Myosin tail Myosin_N PF02736.14 GAP88066.1 - 9.4e-06 25.2 0.1 2.3e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Filament PF00038.16 GAP88066.1 - 0.00021 20.9 35.4 0.00021 20.9 24.6 10.0 1 1 5 8 8 8 3 Intermediate filament protein AAA_19 PF13245.1 GAP88066.1 - 0.029 14.1 0.0 0.096 12.4 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain zf-C3H1 PF10650.4 GAP88067.1 - 0.15 11.5 0.4 0.24 10.9 0.3 1.3 1 0 0 1 1 1 0 Putative zinc-finger domain DUF904 PF06005.7 GAP88067.1 - 1 9.6 10.1 7 7.0 1.4 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF904) DUF4449 PF14613.1 GAP88068.1 - 0.0051 16.7 0.0 0.015 15.2 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF4449) DUF1828 PF08861.5 GAP88068.1 - 0.036 13.6 0.0 0.13 11.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function DUF1828 Abhydro_lipase PF04083.11 GAP88069.1 - 5.7e-22 76.8 0.1 1e-21 76.0 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 GAP88069.1 - 5.1e-18 65.4 0.0 1.1e-17 64.3 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 GAP88069.1 - 0.00019 20.9 0.0 0.055 12.9 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 GAP88069.1 - 0.00052 19.7 0.0 0.004 16.9 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Pet191_N PF10203.4 GAP88070.1 - 4e-15 55.6 0.4 5.5e-15 55.1 0.3 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Metallophos PF00149.23 GAP88071.1 - 1e-13 51.1 0.0 1.1e-12 47.7 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAP88071.1 - 8.2e-07 28.9 2.7 2.3e-06 27.5 1.9 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain LMBR1 PF04791.11 GAP88071.1 - 0.57 8.6 0.5 0.7 8.4 0.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CAML PF14963.1 GAP88071.1 - 1.1 8.5 7.4 2.1 7.6 5.1 1.5 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Transaldolase PF00923.14 GAP88072.1 - 1.1e-96 323.4 0.4 1.2e-96 323.2 0.3 1.0 1 0 0 1 1 1 1 Transaldolase SNase PF00565.12 GAP88073.1 - 7e-70 232.1 0.4 5e-21 75.0 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 GAP88073.1 - 4.7e-24 84.5 0.0 1.5e-23 82.9 0.0 1.9 2 0 0 2 2 2 1 Tudor domain SMN PF06003.7 GAP88073.1 - 6.5e-05 22.1 0.1 0.00016 20.8 0.1 1.7 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) DUF3334 PF11813.3 GAP88073.1 - 0.12 11.9 0.1 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) Sod_Cu PF00080.15 GAP88074.1 - 2e-45 154.4 5.0 2.3e-45 154.2 3.5 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CNH PF00780.17 GAP88075.1 - 6.4e-63 212.7 0.0 1.2e-62 211.8 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 GAP88075.1 - 3.2e-29 102.0 0.2 5.3e-29 101.3 0.2 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 GAP88075.1 - 5.7e-13 48.9 0.0 5.4e-12 45.8 0.0 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 GAP88075.1 - 3.9e-06 27.0 0.0 1.1e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 PH domain NACHT PF05729.7 GAP88076.1 - 5.4e-11 42.4 0.4 1.7e-10 40.7 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 GAP88076.1 - 1e-06 28.8 0.2 6.4e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAP88076.1 - 2.4e-06 27.6 0.1 1.1e-05 25.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 GAP88076.1 - 0.00078 18.3 0.0 0.0022 16.9 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain Arch_ATPase PF01637.13 GAP88076.1 - 0.0024 17.5 0.1 0.023 14.4 0.0 2.5 2 2 0 2 2 2 1 Archaeal ATPase AAA_29 PF13555.1 GAP88076.1 - 0.0081 15.6 0.1 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 GAP88076.1 - 0.02 15.1 0.0 0.073 13.3 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_10 PF12846.2 GAP88076.1 - 0.024 14.0 0.1 0.082 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain DUF2075 PF09848.4 GAP88076.1 - 0.04 12.8 0.0 0.083 11.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 GAP88076.1 - 0.052 13.7 0.0 0.18 12.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 GAP88076.1 - 0.057 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 GAP88076.1 - 0.082 13.3 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein cobW PF02492.14 GAP88076.1 - 0.085 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Glyco_hydro_43 PF04616.9 GAP88077.1 - 4.8e-25 88.2 0.0 7e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 FG-GAP_2 PF14312.1 GAP88077.1 - 0.18 11.8 4.3 9.5 6.3 1.0 3.5 3 0 0 3 3 3 0 FG-GAP repeat Methyltransf_23 PF13489.1 GAP88078.1 - 6.6e-20 71.4 0.0 1.1e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP88078.1 - 8.8e-11 42.1 0.0 1.6e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP88078.1 - 2.8e-09 36.7 0.0 2.8e-08 33.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP88078.1 - 5.9e-08 33.0 0.0 2e-07 31.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP88078.1 - 8e-08 32.8 0.0 3.7e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP88078.1 - 1.3e-06 28.6 0.0 2.8e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP88078.1 - 1.1e-05 24.7 0.0 0.0001 21.4 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 GAP88078.1 - 7.6e-05 22.7 0.0 0.00021 21.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAP88078.1 - 0.0006 19.2 0.0 0.00096 18.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 GAP88078.1 - 0.0019 17.2 0.0 0.0031 16.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 GAP88078.1 - 0.0096 15.0 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 GAP88078.1 - 0.014 14.8 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.14 GAP88078.1 - 0.023 14.6 0.0 0.19 11.7 0.0 2.2 3 0 0 3 3 2 0 FtsJ-like methyltransferase CMAS PF02353.15 GAP88078.1 - 0.046 12.7 0.0 0.082 11.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 GAP88078.1 - 0.076 12.1 0.0 1.5 7.9 0.0 2.4 3 0 0 3 3 3 0 O-methyltransferase FmrO PF07091.6 GAP88078.1 - 0.16 10.9 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) BTB PF00651.26 GAP88079.1 - 3e-27 94.7 0.2 5.5e-14 52.1 0.2 3.1 3 0 0 3 3 3 2 BTB/POZ domain Ank PF00023.25 GAP88079.1 - 1.8e-10 40.0 0.4 3.1e-05 23.5 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 GAP88079.1 - 3.3e-09 36.9 0.0 7.2e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAP88079.1 - 1.1e-07 32.1 0.1 3.4e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP88079.1 - 2e-06 27.8 0.1 5.1e-06 26.5 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP88079.1 - 6.2e-05 22.8 0.1 0.011 15.9 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Lipase_GDSL_2 PF13472.1 GAP88080.1 - 9.4e-10 38.9 0.0 1.3e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAP88080.1 - 8.8e-07 28.9 0.0 1.2e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 GAP88080.1 - 0.0026 17.5 0.0 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Cadherin_pro PF08758.6 GAP88081.1 - 0.011 15.5 1.3 6.5 6.6 0.0 3.3 3 0 0 3 3 3 0 Cadherin prodomain like MCE PF02470.15 GAP88082.1 - 0.0034 17.3 0.1 0.0057 16.6 0.1 1.5 1 1 0 1 1 1 1 mce related protein DUF3433 PF11915.3 GAP88083.1 - 7e-26 90.2 14.5 3.2e-24 84.9 0.9 3.5 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Alpha-2-MRAP_C PF06401.6 GAP88083.1 - 0.057 13.2 0.0 0.096 12.5 0.0 1.2 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain DUF1191 PF06697.7 GAP88083.1 - 1.3 7.7 3.2 4.3 6.0 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) DUF3678 PF12435.3 GAP88084.1 - 5.2 6.7 6.7 26 4.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Tyrosinase PF00264.15 GAP88085.1 - 9.2e-35 120.8 0.2 1.3e-34 120.3 0.2 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase GNAT_acetyltr_2 PF13718.1 GAP88086.1 - 1.1e-75 253.3 0.0 1.7e-75 252.6 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 GAP88086.1 - 2.3e-63 213.0 0.0 3.9e-63 212.2 0.0 1.4 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 GAP88086.1 - 7.4e-37 124.9 0.1 2.1e-36 123.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 GAP88086.1 - 1.6e-27 95.5 0.0 5.7e-27 93.7 0.0 2.0 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 GAP88086.1 - 0.00038 20.5 0.0 0.0018 18.4 0.0 2.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Cyto_heme_lyase PF01265.12 GAP88087.1 - 2.3 7.7 6.9 54 3.2 4.8 2.1 1 1 0 1 1 1 0 Cytochrome c/c1 heme lyase adh_short PF00106.20 GAP88088.1 - 1.9e-26 92.9 1.3 2.6e-26 92.5 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP88088.1 - 2.1e-13 50.3 0.6 2.9e-13 49.8 0.4 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAP88088.1 - 4.5e-13 49.5 0.0 6.4e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 GAP88088.1 - 0.0013 18.4 0.3 0.011 15.4 0.5 2.2 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 GAP88088.1 - 0.017 14.0 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Peptidase_M50B PF13398.1 GAP88089.1 - 1.4e-55 187.8 21.5 1.8e-55 187.4 14.9 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.17 GAP88089.1 - 0.004 16.1 0.6 0.004 16.1 0.4 2.7 3 1 1 4 4 4 1 Peptidase family M50 YlaC PF10777.4 GAP88089.1 - 0.018 14.5 0.1 0.018 14.5 0.1 1.9 2 0 0 2 2 2 0 Inner membrane protein YlaC Peptidase_M41 PF01434.13 GAP88089.1 - 0.095 12.1 0.2 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Peptidase family M41 Patched PF02460.13 GAP88089.1 - 1.5 6.6 6.7 2.1 6.1 4.7 1.1 1 0 0 1 1 1 0 Patched family EF-hand_1 PF00036.27 GAP88090.1 - 4e-14 50.7 0.8 6.4e-05 21.9 0.0 4.4 4 0 0 4 4 4 2 EF hand ZZ PF00569.12 GAP88090.1 - 4.9e-12 45.1 7.0 7.9e-12 44.5 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_7 PF13499.1 GAP88090.1 - 1.2e-09 38.1 4.2 0.001 19.1 0.1 4.7 6 0 0 6 6 6 2 EF-hand domain pair EF-hand_6 PF13405.1 GAP88090.1 - 6.3e-09 34.9 1.9 0.00037 20.1 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 GAP88090.1 - 7.8e-08 31.8 0.7 0.056 13.0 0.0 4.3 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.1 GAP88090.1 - 0.0035 16.6 12.1 0.062 12.6 0.1 3.9 5 0 0 5 5 5 2 EF hand C1_3 PF07649.7 GAP88090.1 - 7.6 6.6 8.9 13 5.9 6.1 1.4 1 0 0 1 1 1 0 C1-like domain ADH_N PF08240.7 GAP88091.1 - 5.2e-06 26.1 0.7 1.5e-05 24.7 0.2 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF2314 PF10077.4 GAP88091.1 - 0.0036 17.3 0.1 0.0069 16.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2314) p450 PF00067.17 GAP88092.1 - 5.9e-52 176.7 0.0 8.1e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Reticulon PF02453.12 GAP88092.1 - 0.0046 16.5 0.0 0.013 15.1 0.0 1.7 1 0 0 1 1 1 1 Reticulon Methyltransf_23 PF13489.1 GAP88093.1 - 6.5e-19 68.2 0.0 9.9e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP88093.1 - 3.3e-11 43.7 0.0 1.2e-10 42.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP88093.1 - 9.2e-10 38.3 0.0 6.8e-09 35.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP88093.1 - 1.1e-07 32.1 0.0 1.9e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP88093.1 - 1.6e-07 31.6 0.0 6.2e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 GAP88093.1 - 0.00031 20.2 0.0 0.00049 19.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 GAP88093.1 - 0.0007 19.9 0.0 0.0025 18.1 0.0 2.0 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAP88093.1 - 0.015 14.3 0.0 0.026 13.5 0.0 1.4 1 1 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 GAP88093.1 - 0.017 14.5 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 GAP88093.1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 GAP88093.1 - 0.044 12.9 0.0 0.085 11.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF3129 PF11327.3 GAP88094.1 - 9.1e-55 185.3 11.3 9.1e-55 185.3 7.8 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3129) DUF4149 PF13664.1 GAP88096.1 - 9.8e-20 70.5 4.8 9.8e-20 70.5 3.3 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Abhydrolase_6 PF12697.2 GAP88097.1 - 1.3e-22 80.7 1.9 2.5e-22 79.9 1.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP88097.1 - 1.8e-14 53.8 0.1 3.2e-14 53.0 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP88097.1 - 4.9e-09 36.0 0.0 9e-09 35.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2048 PF09752.4 GAP88097.1 - 0.00014 20.8 0.0 0.00021 20.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Hydrolase_4 PF12146.3 GAP88097.1 - 0.00065 19.5 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF1100 PF06500.6 GAP88097.1 - 0.0046 15.5 0.0 0.0061 15.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_3 PF07859.8 GAP88097.1 - 0.011 15.3 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.8 GAP88097.1 - 0.014 14.9 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_2 PF02230.11 GAP88097.1 - 0.026 13.9 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Thioesterase PF00975.15 GAP88097.1 - 0.04 14.1 0.1 0.12 12.6 0.0 1.8 2 0 0 2 2 2 0 Thioesterase domain SIS_2 PF13580.1 GAP88097.1 - 0.1 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 SIS domain UPF0227 PF05728.7 GAP88097.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) BAAT_C PF08840.6 GAP88097.1 - 0.17 11.5 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Dicty_REP PF05086.7 GAP88098.1 - 3 5.4 5.2 5.1 4.7 3.6 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Abhydrolase_5 PF12695.2 GAP88099.1 - 8.6e-15 54.7 0.0 1.9e-14 53.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP88099.1 - 1.4e-12 47.9 0.0 2e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP88099.1 - 1.1e-06 28.3 0.1 2.4e-06 27.2 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 GAP88099.1 - 2.2e-05 24.1 0.0 3.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 GAP88099.1 - 0.00049 19.8 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 GAP88099.1 - 0.0053 16.2 0.5 0.019 14.3 0.1 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 GAP88099.1 - 0.0081 15.7 0.1 0.019 14.5 0.1 1.6 1 0 0 1 1 1 1 Lipase (class 3) Peptidase_S15 PF02129.13 GAP88099.1 - 0.025 13.9 0.2 0.049 13.0 0.0 1.5 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF1057 PF06342.7 GAP88099.1 - 0.059 12.1 0.0 0.089 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Peptidase_S9 PF00326.16 GAP88099.1 - 0.13 11.4 0.1 0.5 9.5 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family NMT_C PF02799.10 GAP88100.1 - 5.1e-76 254.2 0.1 7.7e-76 253.7 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 GAP88100.1 - 9.9e-75 249.5 0.0 1.7e-74 248.8 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 GAP88100.1 - 0.00037 20.3 0.0 0.0038 17.0 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain AhpC-TSA PF00578.16 GAP88101.1 - 2.8e-32 110.9 0.0 3.8e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 GAP88101.1 - 2.2e-13 50.0 0.0 2.9e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 GAP88101.1 - 1.9e-12 46.6 0.2 3.4e-12 45.8 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Kelch_4 PF13418.1 GAP88102.1 - 1.9e-20 72.3 0.8 1.1e-09 37.9 0.0 5.1 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 GAP88102.1 - 2.3e-16 59.4 19.2 4e-11 42.7 0.0 6.0 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_1 PF01344.20 GAP88102.1 - 1.9e-11 43.2 0.1 0.00025 20.5 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 GAP88102.1 - 2.2e-10 40.2 5.3 0.0077 16.3 0.7 5.2 3 1 1 4 4 4 3 Kelch motif Kelch_5 PF13854.1 GAP88102.1 - 1.3e-08 34.5 14.9 2.2e-05 24.2 0.3 4.8 4 2 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 GAP88102.1 - 1.5e-08 34.0 3.0 0.00027 20.5 0.0 4.8 4 1 0 4 4 4 2 Kelch motif BTB PF00651.26 GAP88102.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain Abhydrolase_5 PF12695.2 GAP88103.1 - 1.8e-08 34.2 0.0 4.9e-08 32.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP88103.1 - 2.9e-07 30.6 3.0 1.8e-06 28.0 2.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 GAP88103.1 - 0.00019 20.9 0.1 0.00083 18.8 0.0 1.9 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 GAP88103.1 - 0.0062 15.7 0.1 0.21 10.7 0.0 2.6 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 GAP88103.1 - 0.079 12.5 0.8 1.4 8.4 0.0 2.5 2 1 0 2 2 2 0 alpha/beta hydrolase fold DUF3336 PF11815.3 GAP88104.1 - 1.4e-37 128.3 1.1 2.4e-37 127.6 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 GAP88104.1 - 1.4e-23 83.9 0.0 2.5e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Zn_clus PF00172.13 GAP88105.1 - 1.8e-19 69.3 25.4 8.1e-10 38.4 5.5 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAP88105.1 - 1.5e-15 56.8 0.8 3e-15 55.8 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3446 PF11928.3 GAP88105.1 - 0.014 15.5 10.8 0.014 15.5 7.5 4.6 3 2 1 4 4 4 0 Domain of unknown function (DUF3446) Aldo_ket_red PF00248.16 GAP88106.1 - 1.9e-40 138.4 0.0 2.8e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.16 GAP88106.1 - 0.17 11.8 0.2 0.99 9.4 0.0 2.3 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Grp1_Fun34_YaaH PF01184.14 GAP88109.1 - 1.4e-22 80.0 17.7 1.8e-22 79.6 12.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Pkinase PF00069.20 GAP88110.1 - 1.3e-32 113.0 0.0 2.8e-31 108.6 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP88110.1 - 8.8e-10 38.0 0.0 3.7e-06 26.1 0.0 3.2 4 0 0 4 4 4 2 Protein tyrosine kinase APH PF01636.18 GAP88110.1 - 1.9e-05 24.5 0.5 0.00044 20.0 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 GAP88110.1 - 0.011 14.7 0.1 0.017 14.1 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Bac_DnaA_C PF08299.6 GAP88110.1 - 0.092 12.6 0.4 41 4.1 0.0 3.4 3 0 0 3 3 3 0 Bacterial dnaA protein helix-turn-helix RIO1 PF01163.17 GAP88110.1 - 0.15 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF4482 PF14818.1 GAP88111.1 - 1.4 9.6 6.3 0.19 12.3 1.1 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4482) Cortex-I_coil PF09304.5 GAP88111.1 - 6.8 6.7 10.7 3 7.9 4.6 2.3 1 1 2 3 3 3 0 Cortexillin I, coiled coil Ank PF00023.25 GAP88112.1 - 6.3e-45 148.8 14.9 2.2e-09 36.6 0.1 6.6 6 0 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.2 GAP88112.1 - 3.1e-43 146.0 11.0 6.6e-15 55.2 0.2 3.7 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAP88112.1 - 1.1e-33 114.9 16.2 1.9e-11 44.1 0.1 5.6 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP88112.1 - 4.5e-31 103.7 9.9 1.3e-05 25.0 0.0 7.0 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 GAP88112.1 - 3.3e-28 97.0 13.3 4.9e-10 39.3 0.6 6.7 1 1 6 7 7 7 6 Ankyrin repeats (many copies) NACHT PF05729.7 GAP88112.1 - 3.8e-11 42.9 0.0 8.7e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 GAP88112.1 - 0.019 14.9 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain RVP PF00077.15 GAP88112.1 - 0.18 11.7 1.1 13 5.7 0.1 3.3 2 1 1 3 3 3 0 Retroviral aspartyl protease Glyco_hydro_35 PF01301.14 GAP88114.1 - 3.9e-81 272.8 2.7 8.5e-80 268.4 1.9 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 GAP88114.1 - 7.5e-64 214.4 0.0 1.1e-63 213.8 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 GAP88114.1 - 4.5e-43 146.0 2.6 2.4e-21 76.0 0.2 3.5 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 GAP88114.1 - 7.9e-26 89.2 0.1 2.2e-25 87.8 0.0 1.9 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Cellulase PF00150.13 GAP88114.1 - 4.7e-07 29.2 1.1 1.1e-05 24.8 0.5 2.4 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) AF1Q PF15017.1 GAP88114.1 - 0.01 15.6 0.1 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator Glyco_hydro_53 PF07745.8 GAP88114.1 - 0.047 12.4 0.1 0.12 11.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 Maf PF02545.9 GAP88115.1 - 5.1e-41 139.9 0.0 8.5e-41 139.2 0.0 1.3 1 1 0 1 1 1 1 Maf-like protein HLH PF00010.21 GAP88116.1 - 4.1e-07 29.5 0.0 7.5e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Rab5-bind PF09311.6 GAP88116.1 - 0.034 14.0 1.3 0.074 12.9 0.0 1.8 1 1 1 2 2 2 0 Rabaptin-like protein Umbravirus_LDM PF04817.7 GAP88116.1 - 0.04 13.0 0.5 0.042 12.9 0.3 1.1 1 0 0 1 1 1 0 Umbravirus long distance movement (LDM) family tRNA-synt_2b PF00587.20 GAP88117.1 - 1.7e-48 164.5 0.0 2.2e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAP88117.1 - 3.5e-08 33.2 0.0 6.2e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain LOH1CR12 PF10158.4 GAP88118.1 - 0.0092 15.7 0.1 2.8 7.7 0.0 2.4 2 0 0 2 2 2 2 Tumour suppressor protein bZIP_1 PF00170.16 GAP88119.1 - 7.1e-06 25.8 7.9 1.7e-05 24.7 5.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAP88119.1 - 0.0025 17.5 9.3 0.0064 16.2 6.4 1.6 1 0 0 1 1 1 1 Basic region leucine zipper DUF947 PF06102.7 GAP88119.1 - 0.056 13.2 3.6 0.11 12.3 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF947) HLH PF00010.21 GAP88119.1 - 0.098 12.3 1.7 0.26 11.0 1.2 1.8 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain DAO PF01266.19 GAP88120.1 - 3.3e-49 167.6 0.6 3.9e-49 167.4 0.4 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAP88120.1 - 3.6e-05 23.7 1.0 0.00011 22.1 0.7 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAP88120.1 - 0.00032 20.8 0.1 0.044 13.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAP88120.1 - 0.00076 19.2 1.5 0.0078 15.9 0.1 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 GAP88120.1 - 0.0025 16.9 0.1 0.0052 15.9 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 GAP88120.1 - 0.028 13.3 0.3 0.046 12.6 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAP88120.1 - 0.051 12.4 5.3 0.25 10.1 3.7 2.0 1 1 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 GAP88120.1 - 0.063 12.3 0.1 0.098 11.6 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.15 GAP88120.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HET PF06985.6 GAP88121.1 - 2.3e-25 89.3 4.9 1.2e-21 77.3 3.4 2.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CFEM PF05730.6 GAP88122.1 - 1.3e-12 47.3 10.7 2.2e-12 46.5 7.4 1.4 1 0 0 1 1 1 1 CFEM domain MFS_1 PF07690.11 GAP88123.1 - 1.4e-48 165.4 57.2 2.9e-48 164.3 38.2 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAP88123.1 - 9.3e-18 63.7 26.9 6.3e-17 61.0 18.6 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAP88123.1 - 4e-15 55.3 8.4 4e-15 55.3 5.8 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 GAP88123.1 - 0.0029 15.7 0.8 0.0029 15.7 0.6 1.8 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.17 GAP88124.1 - 1.1e-74 251.7 0.0 1.3e-74 251.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acyl_transf_1 PF00698.16 GAP88125.1 - 3e-66 223.9 0.1 5.3e-66 223.1 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 GAP88125.1 - 3.3e-58 197.1 0.1 6.3e-58 196.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 GAP88125.1 - 2.1e-57 193.7 0.2 4.1e-57 192.7 0.2 1.5 1 0 0 1 1 1 1 KR domain ketoacyl-synt PF00109.21 GAP88125.1 - 1.6e-51 175.2 0.0 6.9e-51 173.1 0.0 2.2 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short PF00106.20 GAP88125.1 - 1.2e-43 148.9 1.9 1.3e-43 148.8 0.1 2.1 2 0 0 2 2 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAP88125.1 - 8.3e-30 103.0 0.2 4.3e-29 100.7 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 GAP88125.1 - 1.8e-19 70.0 0.0 4.4e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 GAP88125.1 - 7.4e-14 51.4 0.0 2e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 GAP88125.1 - 1.6e-10 41.3 0.0 4.6e-10 39.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP88125.1 - 2.9e-10 40.6 0.0 8.9e-10 39.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP88125.1 - 3.3e-10 39.9 0.0 1.3e-09 37.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP88125.1 - 8.1e-09 35.2 0.0 2.2e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 GAP88125.1 - 9e-09 36.2 0.0 1.1e-07 32.8 0.0 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP88125.1 - 7e-08 32.1 0.1 1.5e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 GAP88125.1 - 1.1e-06 28.7 0.2 3e-06 27.3 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.1 GAP88125.1 - 0.00023 21.4 0.0 0.00064 20.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ACP_syn_III PF08545.5 GAP88125.1 - 0.0064 16.1 0.1 0.017 14.7 0.1 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_16 PF10294.4 GAP88125.1 - 0.022 14.2 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 GAP88125.1 - 0.23 10.5 0.0 0.44 9.6 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 GAP88125.1 - 0.25 10.3 0.0 0.46 9.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase UPF0278 PF08745.6 GAP88125.1 - 0.46 9.6 0.0 0.84 8.8 0.0 1.3 1 0 0 1 1 1 0 UPF0278 family AXE1 PF05448.7 GAP88126.1 - 0.034 12.6 0.0 0.067 11.6 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) UPF0075 PF03702.9 GAP88126.1 - 0.11 11.3 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) Zip PF02535.17 GAP88127.1 - 5.1e-50 170.2 0.1 1.2e-49 169.1 0.0 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter Nucleoplasmin PF03066.10 GAP88127.1 - 0.14 11.6 2.5 0.19 11.2 1.7 1.2 1 0 0 1 1 1 0 Nucleoplasmin HupE_UreJ PF04955.7 GAP88127.1 - 0.6 9.3 12.8 0.026 13.8 3.5 2.3 2 1 0 2 2 2 0 HupE / UreJ protein PBP1_TM PF14812.1 GAP88127.1 - 0.79 10.0 4.2 2.1 8.7 2.9 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 GAP88127.1 - 2.4 6.8 8.7 3.5 6.2 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FtsJ PF01728.14 GAP88129.1 - 1.9e-07 31.2 0.0 3e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Rax2 PF12768.2 GAP88130.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Abhydrolase_6 PF12697.2 GAP88131.1 - 7.3e-25 88.1 0.3 8.6e-25 87.9 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP88131.1 - 5.7e-09 35.8 0.1 1.2e-08 34.8 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAP88131.1 - 0.00085 18.9 0.1 0.0015 18.1 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein PE-PPE PF08237.6 GAP88131.1 - 0.021 14.2 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_1 PF00561.15 GAP88131.1 - 0.022 14.3 0.0 0.57 9.6 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 GAP88131.1 - 0.036 13.6 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.15 GAP88131.1 - 0.057 13.6 0.1 0.28 11.3 0.0 1.9 2 0 0 2 2 2 0 Thioesterase domain Oxidored_FMN PF00724.15 GAP88132.1 - 2.1e-94 316.3 0.0 2.4e-94 316.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Aldose_epim PF01263.15 GAP88134.1 - 1.4e-39 136.0 0.0 1.7e-39 135.7 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase GWT1 PF06423.7 GAP88136.1 - 5.6e-43 146.2 6.1 1.6e-42 144.8 4.2 1.8 1 0 0 1 1 1 1 GWT1 Corona_NS3b PF03053.9 GAP88136.1 - 0.59 9.6 5.4 0.51 9.8 0.5 2.3 2 0 0 2 2 2 0 ORF3b coronavirus protein Peptidase_A4 PF01828.12 GAP88138.1 - 1.2e-81 272.7 10.5 1.5e-81 272.4 7.3 1.1 1 0 0 1 1 1 1 Peptidase A4 family Rif1_N PF12231.3 GAP88139.1 - 7.9e-133 443.0 1.0 1.2e-132 442.4 0.7 1.3 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Ric8 PF10165.4 GAP88140.1 - 2.2e-121 405.7 0.0 2.6e-121 405.5 0.0 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Chromo PF00385.19 GAP88141.1 - 9.4e-18 63.6 0.1 1.7e-17 62.7 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 GAP88141.1 - 0.0022 17.6 0.2 0.0052 16.4 0.1 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain PQ-loop PF04193.9 GAP88142.1 - 1.9e-22 78.5 7.0 1.5e-13 50.1 2.5 2.5 2 0 0 2 2 2 2 PQ loop repeat Sulfatase PF00884.18 GAP88143.1 - 1.9e-56 191.5 0.0 2.4e-56 191.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 GAP88143.1 - 3.6e-20 71.5 0.5 1.1e-19 69.9 0.1 2.0 1 1 1 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 GAP88143.1 - 1.9e-07 30.7 0.0 0.0015 17.9 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 GAP88143.1 - 0.05 12.9 0.0 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 Metalloenzyme superfamily Sulfatase_C PF14707.1 GAP88143.1 - 0.064 13.5 0.3 0.22 11.8 0.2 1.8 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase Tox-HDC PF15656.1 GAP88143.1 - 0.17 12.1 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 Toxin with a H, D/N and C signature Med8 PF10232.4 GAP88144.1 - 4.4e-20 72.1 1.4 9.4e-16 58.0 0.1 2.2 2 0 0 2 2 2 2 Mediator of RNA polymerase II transcription complex subunit 8 DUF1319 PF07028.6 GAP88144.1 - 0.014 15.6 0.3 0.082 13.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) DUF3243 PF11588.3 GAP88144.1 - 0.11 12.5 0.1 0.28 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) Ndc1_Nup PF09531.5 GAP88145.1 - 0.34 9.2 2.8 0.41 9.0 1.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HeLo PF14479.1 GAP88146.1 - 0.012 15.3 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 0 Prion-inhibition and propagation Acetyltransf_1 PF00583.19 GAP88147.1 - 0.059 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family MFS_1 PF07690.11 GAP88148.1 - 3e-35 121.5 26.1 3e-35 121.5 18.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3671 PF12420.3 GAP88148.1 - 4 7.4 8.9 4.9 7.1 1.5 3.4 1 1 1 2 2 2 0 Protein of unknown function DUF204 PF02659.10 GAP88148.1 - 6.2 7.0 14.6 4.4 7.5 0.1 4.1 4 0 0 4 4 4 0 Domain of unknown function DUF GFO_IDH_MocA_C PF02894.12 GAP88149.1 - 5.3e-18 64.8 0.4 3.1e-17 62.3 0.2 2.3 2 1 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.17 GAP88149.1 - 7.8e-13 49.0 0.0 1.5e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_1 PF00175.16 GAP88150.1 - 1.4e-29 102.8 0.0 2.4e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 GAP88150.1 - 1.1e-20 73.5 0.0 2.1e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 GAP88150.1 - 2.3e-08 34.1 0.0 0.00017 21.5 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 GAP88150.1 - 0.00077 19.4 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DUF155 PF02582.9 GAP88152.1 - 1.3e-59 201.0 0.1 2.2e-59 200.2 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 XLF PF09302.6 GAP88153.1 - 6.2e-29 100.9 0.0 9.4e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 XLF (XRCC4-like factor) TMF_DNA_bd PF12329.3 GAP88153.1 - 3.5 7.4 7.6 1.4 8.7 0.2 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Fork_head PF00250.13 GAP88154.1 - 5.8e-15 55.0 0.5 1.2e-14 54.0 0.3 1.5 1 0 0 1 1 1 1 Fork head domain Cactin_mid PF10312.4 GAP88155.1 - 2.9e-58 196.3 1.9 4.3e-58 195.7 1.3 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 GAP88155.1 - 1.7e-55 185.9 4.2 2.7e-55 185.2 2.9 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein DUF1087 PF06465.8 GAP88155.1 - 0.025 14.4 1.2 0.25 11.2 0.1 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) DUF1525 PF07511.6 GAP88155.1 - 0.067 13.1 0.1 0.18 11.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) RBM1CTR PF08081.6 GAP88155.1 - 0.07 12.8 2.8 0.2 11.4 1.9 1.7 1 0 0 1 1 1 0 RBM1CTR (NUC064) family Glyco_hydro_62 PF03664.8 GAP88156.1 - 1e-147 490.4 12.9 1.2e-147 490.2 9.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 p450 PF00067.17 GAP88157.1 - 3.4e-68 230.2 0.0 3.9e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aldo_ket_red PF00248.16 GAP88158.1 - 3.5e-65 219.6 0.0 7.7e-65 218.5 0.0 1.5 2 0 0 2 2 2 1 Aldo/keto reductase family GST_C PF00043.20 GAP88158.1 - 1.5e-09 37.6 0.0 4.6e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAP88158.1 - 3e-09 36.6 0.0 6.9e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAP88158.1 - 1.1e-07 31.9 0.0 2.7e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAP88158.1 - 1e-06 29.1 0.0 4.9e-06 26.9 0.0 2.2 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAP88158.1 - 7.5e-05 22.6 0.0 0.00023 21.1 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAP88158.1 - 0.00018 21.6 0.0 0.00041 20.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NAD_binding_4 PF07993.7 GAP88159.1 - 2.9e-35 121.3 0.0 4.4e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 GAP88159.1 - 4e-19 68.3 0.0 1.3e-10 40.2 0.0 2.9 3 0 0 3 3 3 2 AMP-binding enzyme Epimerase PF01370.16 GAP88159.1 - 8.7e-14 51.5 0.0 1.9e-13 50.3 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAP88159.1 - 1.1e-07 31.8 0.0 3.4e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.20 GAP88159.1 - 1.3e-06 28.5 0.0 2.9e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.1 GAP88159.1 - 0.00013 21.9 0.0 0.00049 20.1 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAP88159.1 - 0.00055 18.7 0.0 0.001 17.8 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 GAP88159.1 - 0.0013 18.4 0.0 0.0048 16.5 0.0 2.0 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 GAP88159.1 - 0.0015 17.4 0.0 0.027 13.3 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 GAP88159.1 - 0.029 13.2 0.0 0.092 11.6 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DIT1_PvcA PF05141.7 GAP88160.1 - 8.9e-77 258.1 0.0 1.3e-76 257.6 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.11 GAP88160.1 - 3.9e-24 85.7 0.0 7e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FTA2 PF13095.1 GAP88162.1 - 3.7e-28 98.5 0.0 4.8e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Slx4 PF09494.5 GAP88163.1 - 4.3e-22 77.6 0.0 1.4e-21 76.0 0.0 1.9 2 0 0 2 2 2 1 Slx4 endonuclease AT_hook PF02178.14 GAP88163.1 - 0.01 15.4 15.7 0.081 12.6 3.8 3.6 3 0 0 3 3 3 0 AT hook motif Ribosomal_S21e PF01249.13 GAP88164.1 - 8.2e-38 128.2 0.0 9.1e-38 128.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e FAD_binding_7 PF03441.9 GAP88165.1 - 6.4e-100 333.9 0.3 1.4e-99 332.8 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 GAP88165.1 - 4.1e-41 140.4 0.0 8.5e-41 139.4 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.21 GAP88165.1 - 0.0047 17.1 0.0 0.017 15.3 0.0 1.9 1 0 0 1 1 1 1 Universal stress protein family NUDIX PF00293.23 GAP88166.1 - 6.3e-11 42.0 0.0 1.2e-09 37.8 0.0 2.3 1 1 0 1 1 1 1 NUDIX domain AF-4 PF05110.8 GAP88166.1 - 3.3 5.4 8.2 5.2 4.7 5.7 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein NUDIX PF00293.23 GAP88167.1 - 1.9e-21 76.1 0.0 2.3e-21 75.8 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 GAP88167.1 - 0.0027 17.1 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Lipase_GDSL PF00657.17 GAP88168.1 - 3.1e-13 50.1 0.0 6.3e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 GAP88168.1 - 2e-10 41.0 0.1 3.3e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF1510 PF07423.6 GAP88168.1 - 5.2e-07 29.2 0.3 8.1e-07 28.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Lipase_GDSL_3 PF14606.1 GAP88168.1 - 0.0004 20.1 0.0 0.0011 18.7 0.0 1.8 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DHDPS PF00701.17 GAP88169.1 - 2.3e-30 105.2 0.0 2.5e-26 91.9 0.0 2.0 1 1 1 2 2 2 2 Dihydrodipicolinate synthetase family TPR_10 PF13374.1 GAP88169.1 - 0.14 12.0 0.9 0.39 10.7 0.6 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat WD40 PF00400.27 GAP88170.1 - 2.1e-16 59.0 3.3 2.8e-06 26.9 0.8 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat Ribosomal_L37ae PF01780.14 GAP88170.1 - 0.13 12.1 0.7 0.32 10.9 0.5 1.6 1 0 0 1 1 1 0 Ribosomal L37ae protein family Zn-ribbon_8 PF09723.5 GAP88170.1 - 0.27 11.2 3.6 0.25 11.3 1.1 2.1 1 1 0 1 1 1 0 Zinc ribbon domain PHD PF00628.24 GAP88170.1 - 0.7 9.6 6.6 8.9 6.0 0.3 3.0 2 0 0 2 2 2 0 PHD-finger dCMP_cyt_deam_1 PF00383.17 GAP88171.1 - 7.1e-06 25.6 0.0 1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 GAP88171.1 - 1.4 8.8 8.3 2 8.2 1.0 2.3 1 1 1 2 2 2 0 Bd3614-like deaminase GMC_oxred_N PF00732.14 GAP88172.1 - 1.9e-25 89.6 0.0 3.5e-25 88.7 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAP88172.1 - 1.2e-05 24.4 0.9 0.0011 17.9 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAP88172.1 - 0.0019 18.3 0.0 0.06 13.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP88172.1 - 0.0021 18.0 0.1 0.0076 16.2 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAP88172.1 - 0.0056 15.5 2.2 0.0056 15.5 1.5 2.0 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.9 GAP88172.1 - 0.0057 15.1 0.2 0.012 14.1 0.2 1.5 1 0 0 1 1 1 1 HI0933-like protein GMC_oxred_C PF05199.8 GAP88172.1 - 0.006 16.8 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.12 GAP88172.1 - 0.0093 15.0 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 GAP88172.1 - 0.015 14.3 0.2 0.023 13.7 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 GAP88172.1 - 0.025 14.4 0.1 0.076 12.8 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAP88172.1 - 0.098 11.4 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF2277 PF10041.4 GAP88173.1 - 0.023 14.6 0.1 0.058 13.3 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) JAB PF01398.16 GAP88174.1 - 8.9e-30 102.7 0.0 1.9e-29 101.6 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 GAP88174.1 - 5.2e-27 94.2 1.1 1e-26 93.3 0.8 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 GAP88174.1 - 4.7e-08 32.5 0.0 8.3e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DEAD PF00270.24 GAP88175.1 - 7.4e-27 93.9 0.2 4.9e-25 87.9 0.2 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP88175.1 - 1.3e-20 72.9 0.0 5.1e-20 71.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAP88175.1 - 9.1e-06 25.6 0.0 9.1e-06 25.6 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.9 GAP88175.1 - 0.028 13.0 0.3 0.21 10.0 0.0 2.1 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer Acetyltransf_1 PF00583.19 GAP88177.1 - 9.4e-06 25.5 0.0 8.3e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAP88177.1 - 0.0051 16.9 0.0 0.0089 16.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAP88177.1 - 0.082 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain EthD PF07110.6 GAP88179.1 - 5.8e-19 68.8 0.8 7e-19 68.5 0.5 1.1 1 0 0 1 1 1 1 EthD domain FAD-oxidase_C PF02913.14 GAP88180.1 - 1.6e-58 197.9 0.1 1.6e-58 197.9 0.0 1.6 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 GAP88180.1 - 5.6e-37 126.3 0.0 1.2e-36 125.1 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain AUX_IAA PF02309.11 GAP88181.1 - 0.0017 18.1 2.7 0.0023 17.7 1.9 1.1 1 0 0 1 1 1 1 AUX/IAA family DUF2890 PF11081.3 GAP88181.1 - 0.091 12.8 7.9 0.13 12.3 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DDHD PF02862.12 GAP88181.1 - 0.098 12.4 3.9 0.13 12.0 2.7 1.1 1 0 0 1 1 1 0 DDHD domain RNase_H2-Ydr279 PF09468.5 GAP88181.1 - 0.31 10.1 8.5 0.41 9.7 5.9 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) SOG2 PF10428.4 GAP88181.1 - 0.41 9.2 6.1 0.45 9.1 4.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF2413 PF10310.4 GAP88181.1 - 0.91 8.2 7.4 1.1 7.9 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) CDC45 PF02724.9 GAP88181.1 - 1.1 7.2 5.7 1.3 6.9 3.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Rtf2 PF04641.7 GAP88181.1 - 2.2 7.4 9.5 2.8 7.0 6.6 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger RAP1 PF07218.6 GAP88181.1 - 2.2 6.2 4.4 2.7 5.9 3.1 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Apt1 PF10351.4 GAP88181.1 - 2.5 6.8 5.8 2.9 6.6 4.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Vfa1 PF08432.5 GAP88181.1 - 3.8 7.4 12.0 5.2 7.0 8.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Tyrosinase PF00264.15 GAP88182.1 - 1.6e-38 133.1 0.0 2.1e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase MFS_1 PF07690.11 GAP88183.1 - 9.5e-30 103.4 27.6 9.5e-30 103.4 19.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily SprT-like PF10263.4 GAP88188.1 - 1.6e-13 50.5 0.0 3e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 SprT-like family DUF730 PF05325.6 GAP88188.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF730) zf-RING_2 PF13639.1 GAP88190.1 - 2.8e-13 49.4 6.8 4.4e-13 48.8 4.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAP88190.1 - 8.4e-08 32.2 3.0 1.8e-07 31.1 2.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 GAP88190.1 - 1e-07 31.4 4.1 1.7e-07 30.7 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAP88190.1 - 7.5e-06 25.5 4.0 1.2e-05 24.9 2.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAP88190.1 - 3.6e-05 23.6 5.5 5.9e-05 23.0 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAP88190.1 - 5.3e-05 22.8 2.5 8e-05 22.2 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAP88190.1 - 0.0018 18.0 1.8 0.0034 17.1 1.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 GAP88190.1 - 0.0029 17.1 6.5 0.0049 16.4 4.5 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 GAP88190.1 - 0.055 13.1 0.3 0.15 11.7 0.1 1.9 1 1 1 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.3 GAP88190.1 - 0.11 12.5 3.1 0.27 11.2 2.2 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 GAP88190.1 - 0.17 11.5 5.7 0.31 10.7 3.9 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.1 GAP88190.1 - 0.62 9.9 4.7 1.2 9.0 3.3 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 GAP88190.1 - 0.98 9.5 5.6 1.8 8.6 3.9 1.4 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 GAP88190.1 - 4.6 7.0 8.5 0.26 11.0 1.1 2.0 1 1 0 2 2 2 0 Prokaryotic RING finger family 1 DUF3752 PF12572.3 GAP88191.1 - 1.3e-41 142.2 7.7 1.3e-41 142.2 5.3 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3752) 2OG-FeII_Oxy_2 PF13532.1 GAP88192.1 - 8e-14 51.9 0.0 1.6e-13 50.9 0.0 1.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 GAP88192.1 - 5.9e-07 29.7 0.0 3.3e-06 27.3 0.0 2.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Atrophin-1 PF03154.10 GAP88192.1 - 0.51 8.4 4.9 0.78 7.8 3.4 1.2 1 0 0 1 1 1 0 Atrophin-1 family PIG-P PF08510.7 GAP88193.1 - 1.1e-41 141.4 1.1 2.4e-41 140.2 0.8 1.6 1 1 0 1 1 1 1 PIG-P DUF605 PF04652.11 GAP88193.1 - 0.14 11.5 0.6 0.17 11.2 0.4 1.1 1 0 0 1 1 1 0 Vta1 like ATP-grasp_4 PF13535.1 GAP88194.1 - 1e-16 61.1 0.0 2.2e-16 60.1 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 GAP88194.1 - 5.8e-11 42.1 0.0 9.3e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 GAP88194.1 - 4.4e-05 23.4 0.0 6.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 GAP88194.1 - 0.00022 20.0 0.0 0.00084 18.1 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.14 GAP88194.1 - 0.0016 18.0 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 GAP88194.1 - 0.0087 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 RimK-like ATP-grasp domain CPSase_L_D2 PF02786.12 GAP88194.1 - 0.022 14.0 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_ST PF14397.1 GAP88194.1 - 0.13 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp p450 PF00067.17 GAP88195.1 - 2.6e-43 148.2 0.0 1.5e-42 145.7 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Acetyltransf_10 PF13673.1 GAP88196.1 - 0.011 15.7 0.2 5.5 7.1 0.1 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAP88196.1 - 0.014 15.3 0.2 0.38 10.8 0.0 2.8 3 0 0 3 3 3 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAP88196.1 - 0.088 12.9 0.0 0.29 11.3 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAP88196.1 - 0.1 12.4 0.0 0.27 11.0 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PAF-AH_p_II PF03403.8 GAP88197.1 - 2e-08 32.9 0.1 3.5e-05 22.2 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 GAP88197.1 - 2.7e-08 33.7 0.0 4.4e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP88197.1 - 1.2e-06 28.5 0.4 2.4e-06 27.5 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP88197.1 - 8e-05 22.3 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 GAP88197.1 - 0.0081 15.0 0.1 0.038 12.8 0.0 1.8 2 0 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.3 GAP88197.1 - 0.074 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Chlorophyllase PF07224.6 GAP88197.1 - 0.16 10.7 0.3 0.49 9.1 0.2 1.7 1 1 0 1 1 1 0 Chlorophyllase HET PF06985.6 GAP88199.1 - 6.1e-23 81.5 0.5 6.1e-23 81.5 0.4 2.7 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) NESP55 PF06390.7 GAP88199.1 - 8.8 5.6 50.2 1.7 7.9 6.8 3.2 1 1 2 3 3 3 0 Neuroendocrine-specific golgi protein P55 (NESP55) Peptidase_M28 PF04389.12 GAP88200.1 - 5.1e-27 94.7 0.0 6.2e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 PriCT_2 PF08707.6 GAP88200.1 - 0.26 11.2 2.4 0.4 10.5 0.3 2.2 3 0 0 3 3 3 0 Primase C terminal 2 (PriCT-2) Ribophorin_II PF05817.9 GAP88201.1 - 1.3e-18 66.6 0.2 2.2e-18 65.8 0.1 1.3 1 1 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II PSI_PsaJ PF01701.13 GAP88201.1 - 6.8 6.5 6.5 1.2 8.9 0.8 2.5 3 0 0 3 3 3 0 Photosystem I reaction centre subunit IX / PsaJ CDP-OH_P_transf PF01066.16 GAP88202.1 - 1.3e-18 67.1 3.0 1.3e-18 67.1 2.1 2.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Pkinase PF00069.20 GAP88204.1 - 1.5e-20 73.4 0.0 3e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP88204.1 - 1.3e-10 40.7 0.0 3.9e-10 39.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAP88205.1 - 4.4e-25 88.3 0.0 8.4e-18 64.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain HET PF06985.6 GAP88205.1 - 1.1e-21 77.4 0.0 2.5e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase_Tyr PF07714.12 GAP88205.1 - 5.9e-16 58.3 0.0 6e-15 55.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_3 PF00933.16 GAP88206.1 - 2.6e-54 184.2 0.0 3.8e-54 183.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAP88206.1 - 2.5e-38 131.8 0.0 5.1e-38 130.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAP88206.1 - 8.3e-07 28.8 0.0 1.7e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain HET PF06985.6 GAP88207.1 - 3.8e-34 117.8 0.1 6.8e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) APG6 PF04111.7 GAP88209.1 - 0.0032 16.5 13.2 0.0062 15.6 9.1 1.4 1 0 0 1 1 1 1 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 GAP88209.1 - 0.019 14.8 15.7 0.49 10.2 9.7 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 GAP88209.1 - 0.049 12.8 8.5 0.054 12.6 3.8 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Filament PF00038.16 GAP88209.1 - 0.051 13.0 12.2 0.071 12.5 7.7 1.7 1 1 0 1 1 1 0 Intermediate filament protein AAA_13 PF13166.1 GAP88209.1 - 0.051 12.0 15.5 0.18 10.2 10.2 1.9 1 1 0 1 1 1 0 AAA domain Phage_GP20 PF06810.6 GAP88209.1 - 0.092 12.1 21.6 0.11 11.9 7.4 3.4 1 1 2 3 3 3 0 Phage minor structural protein GP20 DUF4559 PF15112.1 GAP88209.1 - 0.097 11.8 7.8 0.23 10.5 5.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) FlaC_arch PF05377.6 GAP88209.1 - 0.13 12.1 9.7 1.8 8.5 0.2 4.0 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Spc7 PF08317.6 GAP88209.1 - 0.15 10.6 16.3 0.45 9.1 11.1 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein Tropomyosin_1 PF12718.2 GAP88209.1 - 0.2 11.5 20.7 0.38 10.5 11.8 2.6 1 1 1 2 2 2 0 Tropomyosin like Sec8_exocyst PF04048.9 GAP88209.1 - 0.24 11.0 8.8 1.7 8.2 0.1 2.8 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF3138 PF11336.3 GAP88209.1 - 0.36 8.9 1.0 0.52 8.4 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Vfa1 PF08432.5 GAP88209.1 - 0.45 10.5 10.9 1.3 8.9 7.5 1.8 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BLOC1_2 PF10046.4 GAP88209.1 - 0.68 10.1 12.0 0.29 11.3 3.7 3.1 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.10 GAP88209.1 - 1.7 8.1 12.1 2.1 7.9 3.1 3.5 2 1 1 3 3 3 0 Septum formation initiator Atg14 PF10186.4 GAP88209.1 - 2 7.2 15.7 5.2 5.9 10.7 1.8 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ADIP PF11559.3 GAP88209.1 - 2.7 7.8 21.2 0.61 9.9 9.2 3.2 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 GAP88209.1 - 3.4 5.3 9.1 5.7 4.6 6.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_TATA_bd PF12325.3 GAP88209.1 - 5 6.8 22.9 0.018 14.7 5.4 3.5 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding NPV_P10 PF05531.7 GAP88209.1 - 5.7 7.2 9.5 50 4.2 3.0 3.8 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein TMF_DNA_bd PF12329.3 GAP88209.1 - 8.1 6.3 21.1 1.4 8.7 7.5 3.3 2 1 1 3 3 2 0 TATA element modulatory factor 1 DNA binding TMPIT PF07851.8 GAP88209.1 - 8.9 5.2 6.5 18 4.2 4.2 1.7 1 1 0 1 1 1 0 TMPIT-like protein ABC_tran PF00005.22 GAP88211.1 - 5.8e-50 169.1 0.0 7.2e-30 104.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAP88211.1 - 6.2e-30 104.5 29.2 5.9e-17 61.9 12.8 3.9 3 1 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 GAP88211.1 - 1.6e-09 37.3 0.0 0.0017 17.6 0.0 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 GAP88211.1 - 1.1e-05 24.9 0.0 0.0075 15.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 GAP88211.1 - 2.4e-05 23.3 0.0 0.029 13.2 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 GAP88211.1 - 3e-05 23.4 0.5 0.099 12.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 GAP88211.1 - 0.00033 20.7 1.3 0.086 12.8 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 GAP88211.1 - 0.002 18.1 0.5 0.85 9.5 0.0 3.6 2 2 0 3 3 3 1 AAA domain DUF258 PF03193.11 GAP88211.1 - 0.0054 15.9 0.0 2 7.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 GAP88211.1 - 0.0091 15.9 0.3 0.46 10.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.1 GAP88211.1 - 0.017 15.0 0.0 18 5.3 0.0 3.6 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 GAP88211.1 - 0.037 14.3 0.0 0.037 14.3 0.0 3.1 4 0 0 4 4 3 0 AAA domain FtsK_SpoIIIE PF01580.13 GAP88211.1 - 0.038 13.4 0.0 3.2 7.1 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.1 GAP88211.1 - 0.047 13.8 2.1 28 4.8 0.1 3.6 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.12 GAP88211.1 - 0.075 12.8 7.3 0.28 10.9 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_10 PF12846.2 GAP88211.1 - 0.076 12.4 2.6 5 6.4 0.2 2.8 2 1 0 2 2 2 0 AAA-like domain Miro PF08477.8 GAP88211.1 - 0.14 12.6 2.5 4.9 7.6 0.0 2.9 3 0 0 3 3 2 0 Miro-like protein AAA_30 PF13604.1 GAP88211.1 - 0.22 11.0 3.1 16 5.0 0.0 3.7 4 0 0 4 4 4 0 AAA domain Dynamin_N PF00350.18 GAP88211.1 - 1.5 8.5 3.4 60 3.4 0.1 3.4 3 0 0 3 3 3 0 Dynamin family PsbN PF02468.10 GAP88211.1 - 5.4 6.7 11.2 0.37 10.4 0.9 3.4 3 0 0 3 3 3 0 Photosystem II reaction centre N protein (psbN) WD40 PF00400.27 GAP88212.1 - 2.9e-29 99.8 6.5 5.4e-07 29.2 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 GAP88212.1 - 0.00054 19.7 0.0 0.27 10.9 0.0 3.2 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ank_2 PF12796.2 GAP88213.1 - 7.4e-79 260.1 7.5 1.6e-17 63.6 0.0 4.4 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 GAP88213.1 - 2.7e-41 137.3 6.1 2.8e-06 26.8 0.0 8.9 8 1 0 8 8 8 8 Ankyrin repeat Ank_3 PF13606.1 GAP88213.1 - 1.4e-35 117.7 0.0 0.00034 20.5 0.0 8.7 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.1 GAP88213.1 - 6.7e-33 112.4 0.4 1.6e-08 34.8 0.0 7.2 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP88213.1 - 3.6e-19 68.3 6.1 0.00095 19.3 0.0 7.5 4 2 3 7 7 7 5 Ankyrin repeats (many copies) FA PF08736.6 GAP88213.1 - 0.039 13.7 4.0 62 3.5 0.0 5.4 6 0 0 6 6 6 0 FERM adjacent (FA) Glyoxalase_2 PF12681.2 GAP88213.1 - 0.14 12.7 0.1 13 6.4 0.0 3.4 1 1 3 4 4 4 0 Glyoxalase-like domain DUF2384 PF09722.5 GAP88213.1 - 0.33 10.8 2.2 8.2 6.3 0.0 3.8 5 0 0 5 5 5 0 Protein of unknown function (DUF2384) Peptidase_M14 PF00246.19 GAP88214.1 - 1.1e-45 156.4 1.3 1.7e-45 155.8 0.9 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase EIF4E-T PF10477.4 GAP88214.1 - 0.23 10.2 2.5 0.29 9.8 0.8 1.6 2 0 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Pkinase PF00069.20 GAP88215.1 - 3.7e-12 45.9 0.0 7.7e-11 41.6 0.0 2.7 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP88215.1 - 1.1e-07 31.2 0.2 0.0007 18.7 0.1 3.8 3 1 0 3 3 3 3 Protein tyrosine kinase Ank_2 PF12796.2 GAP88216.1 - 1.5e-46 156.6 4.4 1.5e-13 50.8 0.1 5.5 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAP88216.1 - 1e-33 113.4 17.0 5.5e-05 22.7 0.0 10.2 9 1 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.1 GAP88216.1 - 8.7e-33 111.6 10.2 2.6e-06 27.4 0.1 8.4 5 2 4 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP88216.1 - 1.6e-28 95.9 5.5 0.00019 21.3 0.0 9.3 10 0 0 10 10 10 6 Ankyrin repeat Ank_4 PF13637.1 GAP88216.1 - 4.4e-28 97.1 7.7 4.4e-05 23.8 0.0 8.1 3 2 6 9 9 9 8 Ankyrin repeats (many copies) OKR_DC_1_N PF03709.10 GAP88216.1 - 0.064 13.3 0.0 0.52 10.3 0.0 2.3 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain Pyridoxal_deC PF00282.14 GAP88216.1 - 0.092 11.1 0.0 0.62 8.4 0.0 2.0 1 1 1 2 2 2 0 Pyridoxal-dependent decarboxylase conserved domain FAD_binding_4 PF01565.18 GAP88217.1 - 4.8e-22 77.9 0.1 7e-22 77.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP88217.1 - 0.00025 20.8 0.2 0.00056 19.7 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.17 GAP88218.1 - 3.5e-47 160.9 0.0 7e-47 159.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Reticulon PF02453.12 GAP88218.1 - 0.093 12.3 1.3 2.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Reticulon adh_short PF00106.20 GAP88219.1 - 3.7e-13 49.7 0.2 5.6e-13 49.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP88219.1 - 1.3e-07 31.5 0.0 2.1e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAP88219.1 - 6.9e-06 26.0 0.0 4.5e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase YjeF_N PF03853.10 GAP88219.1 - 0.069 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Epimerase PF01370.16 GAP88219.1 - 0.092 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAP88219.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 GAP88220.1 - 1.5e-08 34.7 0.3 3.8e-08 33.4 0.2 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP88220.1 - 0.00024 20.9 0.1 0.00041 20.2 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAP88220.1 - 0.0013 18.1 0.1 0.053 12.9 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Lactococcin PF04369.8 GAP88220.1 - 0.01 15.7 0.2 0.22 11.4 0.0 2.7 3 0 0 3 3 3 0 Lactococcin-like family KR PF08659.5 GAP88220.1 - 0.012 15.2 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 KR domain FAD_binding_4 PF01565.18 GAP88221.1 - 9.5e-22 76.9 1.3 2.5e-21 75.5 0.9 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP88221.1 - 0.0022 17.8 0.2 0.0047 16.8 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Fungal_trans_2 PF11951.3 GAP88222.1 - 1.6e-31 109.2 5.9 3.1e-30 105.0 4.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Trp_DMAT PF11991.3 GAP88223.1 - 4.5e-75 253.1 0.0 5.4e-75 252.8 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Cupin_2 PF07883.6 GAP88224.1 - 0.00011 21.5 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain ketoacyl-synt PF00109.21 GAP88225.1 - 4.3e-61 206.5 0.5 9.2e-61 205.5 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAP88225.1 - 5.9e-55 186.8 0.0 9.6e-55 186.1 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 GAP88225.1 - 2.1e-54 183.9 0.5 6.1e-54 182.4 0.1 2.1 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 GAP88225.1 - 8.3e-54 182.7 0.1 1.5e-53 181.8 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 GAP88225.1 - 5e-42 143.6 0.1 5e-42 143.6 0.1 2.5 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAP88225.1 - 3.7e-37 126.7 0.0 1.2e-36 125.1 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 GAP88225.1 - 1.9e-16 59.7 0.0 6.1e-16 58.1 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAP88225.1 - 2.6e-06 28.3 0.4 1.9e-05 25.5 0.1 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP88225.1 - 9.5e-05 22.1 0.0 0.00024 20.8 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 GAP88225.1 - 0.0086 15.0 0.2 0.017 14.1 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short_C2 PF13561.1 GAP88226.1 - 4.6e-25 88.7 0.0 5.3e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAP88226.1 - 1.4e-19 70.6 1.4 2.5e-19 69.8 1.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP88226.1 - 1.1e-08 35.0 0.2 1.1e-08 35.0 0.1 1.7 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 GAP88226.1 - 0.063 13.0 2.0 0.24 11.2 1.4 2.0 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Cupin_2 PF07883.6 GAP88227.1 - 5.7e-06 25.7 0.0 1.2e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Cupin domain FAD_binding_4 PF01565.18 GAP88228.1 - 3.2e-23 81.7 0.9 6e-23 80.8 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP88228.1 - 7.3e-09 35.4 0.1 1.8e-08 34.1 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.20 GAP88229.1 - 4.1e-21 75.6 0.2 5.3e-21 75.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP88229.1 - 2.5e-09 37.2 0.0 3.3e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP88229.1 - 1.1e-07 31.7 0.1 1.4e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAP88229.1 - 3.4e-05 23.3 0.0 5.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAP88229.1 - 0.049 12.3 0.2 0.062 11.9 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAP88229.1 - 0.13 12.2 0.5 0.33 10.9 0.3 1.8 1 1 0 1 1 1 0 NADH(P)-binding Fungal_trans PF04082.13 GAP88230.1 - 4.6e-16 58.4 0.6 7.5e-16 57.7 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cupin_2 PF07883.6 GAP88231.1 - 4e-06 26.2 0.0 7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Cupin domain adh_short PF00106.20 GAP88232.1 - 7.3e-20 71.5 0.1 9.8e-20 71.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP88232.1 - 4.1e-13 49.6 0.0 5.3e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAP88232.1 - 0.00061 19.2 0.1 0.00085 18.8 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAP88232.1 - 0.0019 18.2 0.0 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding ADH_zinc_N PF00107.21 GAP88232.1 - 0.019 14.4 0.3 0.035 13.6 0.1 1.5 2 0 0 2 2 2 0 Zinc-binding dehydrogenase NAD_binding_3 PF03447.11 GAP88232.1 - 0.05 13.9 0.1 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain p450 PF00067.17 GAP88233.1 - 5e-70 236.3 0.0 6.2e-70 235.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1478 PF07349.6 GAP88233.1 - 0.037 13.4 0.0 0.071 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1478) Sulfatase PF00884.18 GAP88235.1 - 2.4e-75 253.6 0.0 3e-75 253.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 GAP88235.1 - 0.05 13.8 0.1 0.78 10.0 0.1 2.3 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase Sugar_tr PF00083.19 GAP88236.1 - 5.4e-89 298.8 22.6 7e-89 298.4 15.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Glyco_hydro_43 PF04616.9 GAP88236.1 - 2.5e-45 154.7 4.9 4.3e-27 94.9 1.3 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 MFS_1 PF07690.11 GAP88236.1 - 1.5e-13 50.2 21.3 1.5e-13 50.2 14.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_16 PF00722.16 GAP88237.1 - 8.2e-16 57.8 1.1 2e-15 56.5 0.7 1.6 1 1 1 2 2 2 2 Glycosyl hydrolases family 16 SKN1 PF03935.10 GAP88237.1 - 2.7e-05 22.5 0.6 0.062 11.4 0.1 2.2 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) TRAUB PF08164.7 GAP88238.1 - 3.5e-27 94.3 0.7 1.3e-26 92.5 0.0 2.4 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 GAP88238.1 - 2.4e-23 82.7 7.0 2.4e-23 82.7 4.8 2.4 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor ParA PF10609.4 GAP88239.1 - 1.6e-33 114.4 0.3 3.2e-33 113.4 0.2 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 GAP88239.1 - 1.9e-16 60.0 0.0 2.6e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 GAP88239.1 - 1.9e-08 34.3 0.0 8.7e-08 32.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 GAP88239.1 - 7.6e-06 25.1 0.2 0.00011 21.3 0.1 2.4 2 1 1 3 3 3 1 Anion-transporting ATPase MipZ PF09140.6 GAP88239.1 - 1.1e-05 24.6 0.0 2.3e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.13 GAP88239.1 - 0.00011 21.5 0.0 0.026 13.7 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.1 GAP88239.1 - 0.0025 17.2 1.0 0.0085 15.5 0.7 1.9 1 1 0 1 1 1 1 AAA domain AAA_26 PF13500.1 GAP88239.1 - 0.0041 16.7 0.1 2.5 7.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain YhjQ PF06564.7 GAP88239.1 - 0.013 14.8 0.2 0.052 12.8 0.1 1.8 2 0 0 2 2 2 0 YhjQ protein AAA_19 PF13245.1 GAP88239.1 - 0.019 14.7 1.9 2.3 8.0 0.1 2.5 2 1 0 2 2 2 0 Part of AAA domain AAA_10 PF12846.2 GAP88239.1 - 0.083 12.3 0.1 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain ArgK PF03308.11 GAP88239.1 - 0.1 11.3 0.2 0.21 10.3 0.1 1.4 1 0 0 1 1 1 0 ArgK protein DUF4537 PF15057.1 GAP88240.1 - 0.0094 15.7 0.1 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Rad9_Rad53_bind PF08605.5 GAP88240.1 - 0.068 12.9 0.1 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Fungal Rad9-like Rad53-binding Arf PF00025.16 GAP88241.1 - 2.1e-21 75.9 0.1 4.3e-21 74.9 0.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAP88241.1 - 7.2e-05 22.0 0.1 0.00012 21.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 GAP88241.1 - 0.029 13.0 0.2 0.058 12.0 0.1 1.4 1 0 0 1 1 1 0 G-protein alpha subunit Ras PF00071.17 GAP88241.1 - 0.065 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Ras family zf-C2H2 PF00096.21 GAP88242.1 - 0.0033 17.6 3.1 0.0033 17.6 2.1 5.0 4 1 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP88242.1 - 0.0041 17.3 1.8 0.0041 17.3 1.3 5.3 5 0 0 5 5 5 3 C2H2-type zinc finger DUF4475 PF14753.1 GAP88242.1 - 0.025 14.1 0.8 0.046 13.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4475) zf-met PF12874.2 GAP88242.1 - 0.24 11.6 0.2 0.24 11.6 0.1 3.6 4 1 0 4 4 4 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 GAP88242.1 - 7.2 7.0 28.4 0.049 13.9 2.9 5.3 5 0 0 5 5 5 0 Zinc-finger double domain Ank_2 PF12796.2 GAP88244.1 - 4.8e-42 142.1 0.1 3.3e-14 52.9 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAP88244.1 - 5.5e-18 63.7 0.7 0.00018 21.1 0.0 6.3 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.1 GAP88244.1 - 1.4e-14 52.7 0.5 0.054 13.7 0.0 6.2 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.1 GAP88244.1 - 8.4e-14 51.6 0.5 3.3e-06 27.4 0.0 5.8 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP88244.1 - 1.6e-11 44.0 1.2 0.015 15.5 0.0 5.4 3 2 1 5 5 5 4 Ankyrin repeats (many copies) F-box-like PF12937.2 GAP88244.1 - 0.0022 17.6 0.2 0.011 15.4 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 GAP88244.1 - 0.053 13.1 2.1 0.34 10.6 1.5 2.4 1 1 0 1 1 1 0 F-box domain UQ_con PF00179.21 GAP88246.1 - 3e-34 117.4 0.1 3.8e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF572 PF04502.8 GAP88247.1 - 2.7e-51 174.7 0.0 4.3e-51 174.0 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF572) hDGE_amylase PF14701.1 GAP88248.1 - 0.12 11.3 1.2 0.22 10.3 0.1 1.8 2 0 0 2 2 2 0 glucanotransferase domain of human glycogen debranching enzyme VWA_3 PF13768.1 GAP88249.1 - 8.3e-28 97.0 0.0 1.5e-27 96.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 GAP88249.1 - 6.6e-14 51.6 0.0 1.3e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 GAP88249.1 - 8.1e-12 45.5 0.0 1.6e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 GAP88249.1 - 4.4e-09 35.6 0.0 1.1e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 GAP88249.1 - 1.7e-06 27.9 0.0 2.9e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 GAP88249.1 - 0.00014 21.0 0.0 0.00027 20.1 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.4 GAP88249.1 - 0.0028 17.4 0.0 0.0055 16.5 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus SHS2_FTSA PF02491.15 GAP88249.1 - 0.069 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 SHS2 domain inserted in FTSA Hemerythrin PF01814.18 GAP88250.1 - 1.5e-08 34.8 0.0 1.9e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain GFA PF04828.9 GAP88251.1 - 4.3e-10 39.3 0.0 5e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Glyco_hydro_72 PF03198.9 GAP88252.1 - 2.4e-114 381.5 3.2 3.1e-114 381.1 2.2 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 GAP88252.1 - 3.4e-19 69.1 4.4 8.8e-19 67.7 3.0 1.8 1 0 0 1 1 1 1 X8 domain LpxD PF04613.9 GAP88252.1 - 0.43 10.1 2.0 2.7 7.5 0.2 2.3 2 0 0 2 2 2 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Glyco_transf_36 PF06165.6 GAP88253.1 - 7.8e-20 70.7 0.0 1.5e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 36 GT36_AF PF06205.6 GAP88253.1 - 0.028 14.1 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase 36 associated family Phe_ZIP PF08916.6 GAP88253.1 - 0.039 14.2 0.6 0.11 12.7 0.4 1.8 1 0 0 1 1 1 0 Phenylalanine zipper Glyco_hydro_7 PF00840.15 GAP88255.1 - 1.1e-75 254.7 0.2 1.2e-75 254.5 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Glyco_hydro_7 PF00840.15 GAP88256.1 - 1.1e-62 211.8 1.2 1.2e-62 211.7 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 FAD_binding_3 PF01494.14 GAP88257.1 - 2.2e-68 230.9 0.0 2.3e-62 211.1 0.0 2.2 1 1 1 2 2 2 2 FAD binding domain MFS_1 PF07690.11 GAP88257.1 - 1.8e-32 112.4 26.0 6.1e-32 110.7 17.9 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Acyl_CoA_thio PF02551.10 GAP88257.1 - 0.18 11.4 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA thioesterase Thi4 PF01946.12 GAP88257.1 - 0.22 10.5 0.0 0.35 9.9 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Amidohydro_1 PF01979.15 GAP88258.1 - 0.023 14.3 0.0 0.025 14.2 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase family Amidohydro_4 PF13147.1 GAP88258.1 - 0.031 14.2 0.1 0.036 14.0 0.1 1.1 1 0 0 1 1 1 0 Amidohydrolase DUF2360 PF10152.4 GAP88260.1 - 3.4 7.9 7.0 5 7.4 4.8 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF2985 PF11204.3 GAP88262.1 - 1.3e-26 92.1 6.1 2.8e-26 91.0 4.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) DUF1469 PF07332.6 GAP88262.1 - 0.011 15.4 1.8 0.41 10.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) MMR_HSR1 PF01926.18 GAP88263.1 - 8.2e-10 38.6 0.2 1.8e-09 37.5 0.2 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 GAP88263.1 - 4.7e-07 29.1 0.1 4.7e-07 29.1 0.1 1.7 2 0 0 2 2 2 1 AIG1 family Septin PF00735.13 GAP88263.1 - 0.0002 20.4 0.0 0.00034 19.7 0.0 1.3 1 0 0 1 1 1 1 Septin DUF258 PF03193.11 GAP88263.1 - 0.00031 19.9 0.1 0.00069 18.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 GAP88263.1 - 0.00058 20.3 0.3 0.0017 18.8 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein FeoB_N PF02421.13 GAP88263.1 - 0.00081 18.7 0.3 0.0021 17.3 0.2 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF3539 PF12058.3 GAP88263.1 - 0.0043 16.8 0.1 0.024 14.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3539) Dynamin_N PF00350.18 GAP88263.1 - 0.0054 16.5 5.0 0.3 10.8 0.2 3.0 2 1 1 3 3 3 1 Dynamin family Arch_ATPase PF01637.13 GAP88263.1 - 0.0057 16.3 0.3 0.71 9.5 0.0 2.6 3 0 0 3 3 3 1 Archaeal ATPase AAA_17 PF13207.1 GAP88263.1 - 0.013 16.2 1.2 0.023 15.5 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 GAP88263.1 - 0.017 15.2 0.2 0.051 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 GAP88263.1 - 0.024 14.5 0.2 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 GAP88263.1 - 0.024 13.4 0.1 0.024 13.4 0.1 1.7 2 0 0 2 2 2 0 NB-ARC domain ABC_tran PF00005.22 GAP88263.1 - 0.027 14.7 1.4 0.07 13.4 0.9 2.0 1 1 0 1 1 1 0 ABC transporter SAM_MT PF04445.8 GAP88263.1 - 0.029 13.5 0.0 0.065 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Kinesin PF00225.18 GAP88263.1 - 0.032 12.9 0.1 0.032 12.9 0.1 1.5 2 0 0 2 2 2 0 Kinesin motor domain IIGP PF05049.8 GAP88263.1 - 0.042 12.6 0.8 0.91 8.2 0.1 2.2 1 1 1 2 2 2 0 Interferon-inducible GTPase (IIGP) cobW PF02492.14 GAP88263.1 - 0.051 13.0 0.1 0.091 12.1 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 GAP88263.1 - 0.065 12.7 0.5 0.065 12.7 0.4 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein IncA PF04156.9 GAP88263.1 - 0.068 12.7 3.1 0.11 12.1 2.1 1.2 1 0 0 1 1 1 0 IncA protein AAA_23 PF13476.1 GAP88263.1 - 0.11 12.7 5.2 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 GAP88263.1 - 0.11 12.7 0.8 0.5 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 GAP88263.1 - 0.13 11.6 0.2 0.13 11.6 0.1 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MobB PF03205.9 GAP88263.1 - 0.14 11.8 0.8 0.33 10.6 0.5 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF883 PF05957.8 GAP88263.1 - 0.14 12.5 4.3 0.25 11.7 3.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) T2SE PF00437.15 GAP88263.1 - 0.3 9.9 2.5 0.22 10.3 0.3 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF3782 PF12644.2 GAP88263.1 - 4.2 7.2 6.6 11 5.9 4.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) Cupin_8 PF13621.1 GAP88264.1 - 2.2e-25 89.6 0.0 2.7e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 GAP88264.1 - 6.8e-05 22.2 0.5 0.0013 18.0 0.0 2.1 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.17 GAP88264.1 - 0.0011 19.2 0.0 0.0025 18.0 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 GAP88264.1 - 0.013 15.0 0.0 0.032 13.7 0.0 1.6 1 0 0 1 1 1 0 Cupin domain CK_II_beta PF01214.13 GAP88265.1 - 2.9e-76 255.0 0.0 7.7e-76 253.6 0.0 1.6 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 GAP88265.1 - 0.016 15.8 6.2 0.016 15.8 4.3 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Myc_N PF01056.13 GAP88265.1 - 0.12 11.4 4.5 0.22 10.6 1.7 1.9 2 0 0 2 2 2 0 Myc amino-terminal region Nop25 PF09805.4 GAP88265.1 - 0.48 10.4 4.9 0.35 10.9 1.6 1.8 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Nucleoplasmin PF03066.10 GAP88265.1 - 2.1 7.8 12.3 0.7 9.4 5.1 2.0 2 0 0 2 2 2 0 Nucleoplasmin PBP1_TM PF14812.1 GAP88265.1 - 4.4 7.6 13.1 3.4 8.0 3.6 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ABC2_membrane PF01061.19 GAP88266.1 - 1.6e-81 272.4 51.1 4.8e-43 146.7 14.5 3.0 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 GAP88266.1 - 4.2e-36 124.2 0.0 1.6e-17 64.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 GAP88266.1 - 2.7e-31 107.2 6.4 1.1e-25 89.2 0.0 3.0 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 GAP88266.1 - 3.9e-09 36.0 34.1 1.1e-07 31.2 7.5 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 GAP88266.1 - 5.3e-08 32.8 0.1 2.3e-07 30.7 0.0 2.2 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 GAP88266.1 - 3.2e-06 26.6 0.1 0.014 14.8 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.1 GAP88266.1 - 1.2e-05 25.1 0.1 0.014 15.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 GAP88266.1 - 1.8e-05 24.8 0.0 0.072 13.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain cobW PF02492.14 GAP88266.1 - 7e-05 22.3 0.5 0.0054 16.1 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 GAP88266.1 - 7.5e-05 22.1 0.1 0.0056 16.1 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 GAP88266.1 - 0.00011 23.0 0.1 0.048 14.4 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.1 GAP88266.1 - 0.00012 22.2 0.0 0.15 12.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 GAP88266.1 - 0.00023 20.8 0.2 0.32 10.6 0.1 2.5 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 GAP88266.1 - 0.00032 20.6 0.9 0.061 13.2 0.0 3.4 4 0 0 4 4 3 1 AAA domain AAA_19 PF13245.1 GAP88266.1 - 0.0004 20.0 0.3 1.1 9.0 0.0 3.6 3 0 0 3 3 3 1 Part of AAA domain AAA_16 PF13191.1 GAP88266.1 - 0.00074 19.5 0.3 0.16 11.9 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 GAP88266.1 - 0.00084 18.5 0.0 0.0044 16.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NACHT PF05729.7 GAP88266.1 - 0.001 18.7 0.4 0.9 9.1 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.1 GAP88266.1 - 0.0015 18.8 0.0 0.16 12.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 GAP88266.1 - 0.0044 16.2 0.1 0.5 9.5 0.0 3.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA PF00004.24 GAP88266.1 - 0.0076 16.4 0.1 4.3 7.5 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 GAP88266.1 - 0.026 14.2 0.0 2.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase PduV-EutP PF10662.4 GAP88266.1 - 0.033 13.6 0.2 2.3 7.6 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 GAP88266.1 - 0.038 13.4 0.0 1.8 8.0 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 GAP88266.1 - 0.046 13.1 0.2 2.2 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 GAP88266.1 - 0.077 13.1 0.5 60 3.8 0.0 3.6 3 0 0 3 3 3 0 RNA helicase Miro PF08477.8 GAP88266.1 - 0.079 13.4 0.0 5.2 7.5 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 GAP88266.1 - 0.09 13.0 0.2 0.61 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 GAP88266.1 - 0.12 11.9 0.3 6.4 6.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 GAP88266.1 - 0.4 9.6 0.0 3 6.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain B_lectin PF01453.19 GAP88267.1 - 1.1e-13 51.0 2.1 6.3e-11 42.1 0.1 2.1 1 1 1 2 2 2 2 D-mannose binding lectin Peroxidase_2 PF01328.12 GAP88269.1 - 2.3e-33 115.1 0.0 3.1e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Zn_clus PF00172.13 GAP88270.1 - 5e-08 32.7 9.0 8.3e-08 32.0 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med3 PF11593.3 GAP88270.1 - 2.8 7.1 5.2 4.2 6.5 3.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Scs3p PF10261.4 GAP88271.1 - 1.4 7.8 5.2 2.3 7.2 3.6 1.6 1 1 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF3425 PF11905.3 GAP88272.1 - 3.5e-23 81.9 0.0 6.5e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) DUF1180 PF06679.7 GAP88272.1 - 0.99 9.2 4.9 1.8 8.4 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) adh_short PF00106.20 GAP88273.1 - 1.8e-10 41.0 0.0 3.7e-10 39.9 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAP88273.1 - 5.6e-05 22.8 0.0 9.5e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAP88273.1 - 0.011 15.7 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 0 NADH(P)-binding Shikimate_DH PF01488.15 GAP88273.1 - 0.015 15.3 0.0 0.024 14.7 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 GAP88273.1 - 0.045 13.1 0.0 0.14 11.5 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 GAP88273.1 - 0.08 12.6 0.0 0.16 11.7 0.0 1.4 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Prp19 PF08606.6 GAP88273.1 - 0.13 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Prp19/Pso4-like Pkinase PF00069.20 GAP88274.1 - 6.5e-18 64.8 0.0 1.6e-17 63.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP88274.1 - 2.4e-09 36.6 0.0 1.4e-08 34.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Aminotran_4 PF01063.14 GAP88275.1 - 2.3e-30 105.7 0.0 3.8e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV ESSS PF10183.4 GAP88276.1 - 6e-28 97.3 0.2 7.2e-28 97.0 0.2 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ATP-synt_E PF05680.7 GAP88276.1 - 0.0034 17.2 0.0 0.0068 16.3 0.0 1.5 1 0 0 1 1 1 1 ATP synthase E chain Seipin PF06775.9 GAP88278.1 - 2.8e-50 170.5 2.6 3.6e-50 170.2 1.8 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) MtN3_slv PF03083.11 GAP88278.1 - 0.68 9.8 3.9 0.43 10.4 0.2 2.4 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange FCH PF00611.18 GAP88279.1 - 3.2e-20 72.0 0.0 9.1e-20 70.6 0.0 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 GAP88279.1 - 1.2e-12 47.0 0.0 2.3e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAP88279.1 - 1.8e-10 40.1 0.0 7.7e-10 38.1 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 GAP88279.1 - 5.1e-10 38.7 0.1 1.3e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Polyketide_cyc2 PF10604.4 GAP88280.1 - 1.3e-06 28.6 0.2 1.5e-06 28.4 0.2 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport CBM_1 PF00734.13 GAP88281.1 - 4e-13 48.7 7.9 1.3e-12 47.1 5.5 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Polysacc_lyase PF14099.1 GAP88281.1 - 0.00036 20.2 4.3 0.00057 19.6 3.0 1.3 1 0 0 1 1 1 1 Polysaccharide lyase DUF3595 PF12166.3 GAP88281.1 - 0.014 14.2 2.0 0.033 12.9 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3595) DUF3301 PF11743.3 GAP88281.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) Sporozoite_P67 PF05642.6 GAP88281.1 - 2.3 5.9 8.1 2.9 5.6 5.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PepSY_TM_1 PF13172.1 GAP88282.1 - 0.16 11.8 4.6 0.33 10.7 3.2 1.6 1 0 0 1 1 1 0 PepSY-associated TM helix DUF346 PF03984.8 GAP88282.1 - 0.23 10.9 20.0 0.63 9.5 0.3 5.7 5 0 0 5 5 5 0 Repeat of unknown function (DUF346) Arginosuc_synth PF00764.14 GAP88285.1 - 2.3e-139 464.7 0.0 2.7e-139 464.5 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 GAP88285.1 - 0.00018 21.0 0.0 0.00026 20.5 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 GAP88285.1 - 0.0024 17.1 0.0 0.0045 16.2 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 GAP88285.1 - 0.016 13.7 0.0 0.027 13.0 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase p450 PF00067.17 GAP88286.1 - 7.6e-52 176.3 0.0 1e-51 175.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.6 GAP88287.1 - 1.6e-27 96.3 0.1 2.5e-27 95.7 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_M24 PF00557.19 GAP88288.1 - 2.7e-19 69.5 0.0 3.4e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Metal_resist PF13801.1 GAP88288.1 - 1.4 8.8 11.3 2.6 8.0 6.8 2.0 2 0 0 2 2 2 0 Heavy-metal resistance adh_short PF00106.20 GAP88289.1 - 4.4e-19 68.9 2.9 6e-19 68.5 2.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP88289.1 - 7.6e-07 28.9 0.8 1.1e-06 28.4 0.5 1.3 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAP88289.1 - 7.2e-05 22.6 0.0 9.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_hydro_3 PF00933.16 GAP88290.1 - 4e-88 295.2 0.0 5.6e-88 294.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAP88290.1 - 9.3e-46 156.1 0.0 1.4e-44 152.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAP88290.1 - 3.3e-24 84.5 0.0 6.8e-24 83.6 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain CN_hydrolase PF00795.17 GAP88292.1 - 1e-27 96.6 0.0 1.4e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase adh_short PF00106.20 GAP88295.1 - 2.5e-13 50.3 0.1 2.5e-13 50.3 0.1 2.3 2 1 1 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP88295.1 - 8.8e-06 25.6 0.0 0.00015 21.6 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP88295.1 - 1.5e-05 24.7 0.4 3.6e-05 23.4 0.1 1.9 2 0 0 2 2 2 1 KR domain CLN6 PF15156.1 GAP88295.1 - 0.19 10.8 0.0 0.36 9.9 0.0 1.4 1 0 0 1 1 1 0 Ceroid-lipofuscinosis neuronal protein 6 p450 PF00067.17 GAP88296.1 - 3e-78 263.4 0.0 4e-78 263.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Amidohydro_2 PF04909.9 GAP88297.1 - 4.4e-35 121.5 0.1 5.3e-35 121.3 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase ketoacyl-synt PF00109.21 GAP88298.1 - 2.3e-86 289.4 0.3 1e-85 287.2 0.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAP88298.1 - 2.2e-81 273.6 0.0 3.4e-81 273.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 GAP88298.1 - 2.3e-61 206.6 0.3 1.3e-60 204.2 0.0 2.5 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 GAP88298.1 - 1.6e-52 177.7 0.0 5.2e-52 176.1 0.0 2.0 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAP88298.1 - 2.8e-37 127.1 1.8 2.8e-37 127.1 1.3 2.7 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 GAP88298.1 - 1.1e-13 51.0 0.0 1.9e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 GAP88298.1 - 2.2e-09 37.4 0.0 5.8e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 GAP88298.1 - 0.00015 20.8 1.0 0.00025 20.1 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain VHS PF00790.14 GAP88300.1 - 7.4e-24 83.9 0.0 1.5e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 GAP88300.1 - 2.1e-10 40.4 0.7 4.6e-10 39.3 0.5 1.5 1 0 0 1 1 1 1 GAT domain CALCOCO1 PF07888.6 GAP88300.1 - 0.00031 19.1 1.8 0.00031 19.1 1.2 1.4 2 0 0 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2217 PF10265.4 GAP88300.1 - 0.24 10.1 4.4 0.32 9.7 3.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Myosin_tail_1 PF01576.14 GAP88301.1 - 0.052 11.2 6.9 0.072 10.8 4.8 1.1 1 0 0 1 1 1 0 Myosin tail zf-P11 PF03854.9 GAP88301.1 - 0.12 11.8 0.1 0.12 11.8 0.1 2.4 2 0 0 2 2 2 0 P-11 zinc finger Synaptobrevin PF00957.16 GAP88301.1 - 0.31 10.6 1.0 0.62 9.7 0.7 1.4 1 0 0 1 1 1 0 Synaptobrevin Ion_trans_2 PF07885.11 GAP88302.1 - 2.7e-28 97.4 22.4 1.7e-15 56.4 1.2 3.2 3 1 0 3 3 3 2 Ion channel Keratin_assoc PF09775.4 GAP88302.1 - 0.014 14.9 3.9 0.034 13.7 2.7 1.5 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 Abhydrolase_3 PF07859.8 GAP88303.1 - 0.00036 20.1 0.0 0.00079 19.0 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold MAGE_N PF12440.3 GAP88303.1 - 0.079 13.2 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Abhydrolase_2 PF02230.11 GAP88303.1 - 0.17 11.2 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Ribosomal_S24e PF01282.14 GAP88304.1 - 1.8e-29 101.3 0.6 3.3e-29 100.5 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S24e Peptidase_C14 PF00656.17 GAP88304.1 - 0.014 15.0 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 Caspase domain SelB-wing_2 PF09106.6 GAP88304.1 - 0.073 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Elongation factor SelB, winged helix His_Phos_1 PF00300.17 GAP88305.1 - 3.7e-17 62.8 0.0 1.2e-15 57.9 0.0 2.0 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) RR_TM4-6 PF06459.7 GAP88306.1 - 4.7 7.0 14.8 5.8 6.7 10.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PTPA PF03095.10 GAP88307.1 - 3e-112 374.6 0.0 3.6e-112 374.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Bap31 PF05529.7 GAP88309.1 - 0.048 13.1 0.2 0.048 13.1 0.1 11.8 3 2 3 6 6 6 0 B-cell receptor-associated protein 31-like Filament PF00038.16 GAP88309.1 - 0.14 11.6 157.6 0.018 14.4 8.2 8.7 1 1 6 7 7 7 0 Intermediate filament protein Pox_A_type_inc PF04508.7 GAP88309.1 - 3.6 7.6 13.1 38 4.4 0.8 6.7 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat FAD_binding_4 PF01565.18 GAP88310.1 - 3.7e-07 29.6 0.3 6.3e-07 28.9 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP88310.1 - 0.0088 15.9 0.1 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.17 GAP88311.1 - 2.2e-55 188.0 0.0 2.6e-54 184.4 0.0 2.4 1 1 0 1 1 1 1 Cytochrome P450 DUF3439 PF11921.3 GAP88311.1 - 0.68 9.7 4.7 1.3 8.8 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) JmjC PF02373.17 GAP88312.1 - 1.9e-17 63.5 0.0 3.2e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase PS_Dcarbxylase PF02666.10 GAP88313.1 - 8.8e-53 178.6 0.0 1.1e-52 178.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Abhydrolase_6 PF12697.2 GAP88315.1 - 5.2e-05 23.2 0.6 5.6e-05 23.1 0.4 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Granulin PF00396.13 GAP88316.1 - 0.018 15.1 20.5 0.083 13.0 4.4 2.7 2 1 0 2 2 2 0 Granulin Zds_C PF08632.5 GAP88317.1 - 6.9e-32 108.6 1.1 1.2e-31 107.8 0.7 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF2433 PF10360.4 GAP88318.1 - 6.6e-54 181.7 0.0 1.2e-53 180.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) DUF2360 PF10152.4 GAP88318.1 - 6.5e-08 32.9 0.1 2.7e-07 30.9 0.1 1.9 1 1 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) Metallophos_2 PF12850.2 GAP88318.1 - 0.0076 16.0 0.0 0.02 14.7 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RimM PF01782.13 GAP88318.1 - 0.13 12.1 0.1 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 RimM N-terminal domain Ubie_methyltran PF01209.13 GAP88319.1 - 1.7e-49 168.0 0.0 1.9e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 GAP88319.1 - 8.8e-10 38.9 0.0 1.6e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP88319.1 - 5.9e-08 32.4 0.0 7e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP88319.1 - 6e-08 33.0 0.0 8.4e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP88319.1 - 9.7e-07 29.0 0.0 1.6e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP88319.1 - 1.4e-05 24.8 0.0 1.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP88319.1 - 0.015 15.9 0.0 0.026 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 GAP88319.1 - 0.018 15.0 1.2 0.11 12.5 0.8 2.1 1 1 0 1 1 1 0 Methyltransferase domain E1_dh PF00676.15 GAP88320.1 - 2.7e-86 288.9 0.0 3.3e-86 288.7 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 GAP88320.1 - 0.0053 16.3 0.3 0.025 14.1 0.0 2.2 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 GAP88320.1 - 0.061 12.2 0.0 0.21 10.4 0.0 1.8 3 0 0 3 3 3 0 1-deoxy-D-xylulose-5-phosphate synthase HECT PF00632.20 GAP88321.1 - 6.9e-83 278.4 0.0 1.2e-82 277.5 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) CLASP_N PF12348.3 GAP88321.1 - 0.00053 19.4 2.4 0.023 14.0 0.0 3.1 3 0 0 3 3 3 1 CLASP N terminal TFIIA PF03153.8 GAP88321.1 - 0.0036 17.2 31.3 0.0036 17.2 21.7 3.4 3 1 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit HEAT PF02985.17 GAP88321.1 - 0.004 17.1 1.1 0.62 10.2 0.0 4.3 4 0 0 4 4 4 1 HEAT repeat Arm PF00514.18 GAP88321.1 - 0.0044 16.7 1.7 2 8.3 0.0 4.7 4 1 1 5 5 5 1 Armadillo/beta-catenin-like repeat Complex1_30kDa PF00329.14 GAP88323.1 - 5.6e-35 119.6 0.0 8.5e-35 119.1 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit zf-RING_4 PF14570.1 GAP88324.1 - 4.2e-19 67.8 11.1 7.9e-19 66.9 7.7 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 GAP88324.1 - 2.8e-09 36.4 0.0 6.6e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 GAP88324.1 - 5.4e-06 25.9 5.9 9.2e-06 25.2 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 GAP88324.1 - 8.2e-06 25.2 5.2 8.2e-06 25.2 3.6 3.1 3 1 0 3 3 2 1 Rtf2 RING-finger RRM_6 PF14259.1 GAP88324.1 - 2.7e-05 24.0 0.0 7.2e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP88324.1 - 2.8e-05 23.8 0.1 6.3e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 GAP88324.1 - 0.017 14.8 4.5 0.031 13.9 3.1 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Nup35_RRM_2 PF14605.1 GAP88324.1 - 0.025 14.3 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-RING_5 PF14634.1 GAP88324.1 - 0.05 13.3 9.7 0.094 12.4 6.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain FYVE PF01363.16 GAP88324.1 - 0.082 12.8 4.5 0.21 11.5 3.1 1.6 1 0 0 1 1 1 0 FYVE zinc finger SET_assoc PF11767.3 GAP88324.1 - 0.087 12.1 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated RRM_3 PF08777.6 GAP88324.1 - 0.15 11.9 4.7 4.3 7.2 2.4 2.7 2 0 0 2 2 2 0 RNA binding motif zf-C3HC4 PF00097.20 GAP88324.1 - 0.91 9.2 9.6 1.8 8.2 6.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAP88324.1 - 1.5 8.9 10.3 3.1 7.9 7.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 GAP88324.1 - 3.9 7.0 10.5 0.82 9.2 3.1 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 PAS_9 PF13426.1 GAP88325.1 - 5.5e-16 58.8 0.0 6.5e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 GAP88325.1 - 0.018 14.8 0.0 0.033 13.9 0.0 1.7 1 1 0 1 1 1 0 PAS fold PAS_8 PF13188.1 GAP88325.1 - 0.049 13.5 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 PAS domain PAS_3 PF08447.6 GAP88325.1 - 0.075 13.1 0.0 0.55 10.3 0.0 1.9 2 0 0 2 2 2 0 PAS fold Glyco_hydro_7 PF00840.15 GAP88326.1 - 8.5e-183 607.6 25.2 9.9e-183 607.4 17.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Trypan_PARP PF05887.6 GAP88327.1 - 0.013 15.3 5.3 0.021 14.6 3.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pkinase PF00069.20 GAP88328.1 - 0.0043 16.2 0.0 1.5 7.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pyridox_oxidase PF01243.15 GAP88331.1 - 8e-07 28.9 0.0 2.8e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Patched PF02460.13 GAP88332.1 - 1e-76 258.5 7.9 2.2e-50 171.4 0.0 2.1 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 GAP88332.1 - 1.8e-51 173.5 5.3 1.8e-51 173.5 3.7 2.8 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 GAP88332.1 - 8e-06 24.7 7.1 8e-06 24.7 4.9 2.8 2 1 0 2 2 2 1 MMPL family Folate_rec PF03024.9 GAP88332.1 - 1.8e-05 24.4 1.1 4.3e-05 23.2 0.7 1.6 1 0 0 1 1 1 1 Folate receptor family CTP_transf_2 PF01467.21 GAP88333.1 - 5e-27 94.8 0.0 6.6e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase Mnd1 PF03962.10 GAP88333.1 - 0.049 13.2 0.0 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 Mnd1 family YfkB PF08756.5 GAP88334.1 - 0.1 12.2 0.0 0.12 11.9 0.0 1.3 1 1 0 1 1 1 0 YfkB-like domain CUE PF02845.11 GAP88335.1 - 0.004 16.6 0.8 0.21 11.1 0.2 2.6 2 0 0 2 2 2 2 CUE domain DUF1771 PF08590.5 GAP88335.1 - 0.038 14.0 8.9 0.1 12.6 6.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) Lactamase_B_2 PF12706.2 GAP88336.1 - 7e-41 139.9 0.5 9.1e-41 139.5 0.4 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAP88336.1 - 2.9e-09 36.8 0.0 8.6e-09 35.3 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 GAP88336.1 - 7.1e-05 22.5 1.1 0.00017 21.3 0.7 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Gryzun PF07919.7 GAP88337.1 - 1.1e-98 330.9 0.0 1.4e-98 330.6 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 GAP88337.1 - 7.1e-75 251.6 2.7 2.3e-70 236.9 1.5 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.2 GAP88337.1 - 0.00086 19.0 0.0 0.002 17.9 0.0 1.7 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking DUF1622 PF07784.6 GAP88337.1 - 0.0023 17.5 0.0 0.0054 16.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1622) RXT2_N PF08595.6 GAP88338.1 - 3.7e-38 130.6 0.1 3.7e-38 130.6 0.0 2.6 3 0 0 3 3 3 1 RXT2-like, N-terminal Glucodextran_B PF09136.5 GAP88338.1 - 0.088 12.9 0.6 0.15 12.2 0.4 1.3 1 0 0 1 1 1 0 Glucodextranase, domain B PEMT PF04191.8 GAP88339.1 - 1.1e-31 109.0 4.5 1.4e-31 108.7 2.2 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase Nramp PF01566.13 GAP88340.1 - 6.9e-91 304.6 14.7 6.9e-91 304.6 10.2 1.3 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein FGGY_C PF02782.11 GAP88341.1 - 3.9e-73 245.2 0.8 7.1e-73 244.4 0.3 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 GAP88341.1 - 5.3e-61 206.0 0.0 7.3e-61 205.5 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain NAD_binding_4 PF07993.7 GAP88342.1 - 1.8e-32 112.2 0.0 3e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 GAP88342.1 - 6.5e-27 93.9 0.0 9.7e-27 93.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 GAP88342.1 - 3.1e-11 43.3 0.1 6.4e-11 42.3 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 GAP88342.1 - 1.9e-07 30.7 0.0 3.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAP88342.1 - 0.00016 21.6 0.2 0.0015 18.4 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAP88342.1 - 0.014 15.0 0.4 0.26 10.9 0.0 2.8 3 0 0 3 3 3 0 KR domain TRI12 PF06609.8 GAP88343.1 - 2.2e-10 39.3 2.2 2.2e-10 39.3 1.5 1.7 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 GAP88343.1 - 3.7e-08 32.4 38.2 2.2e-07 29.9 7.0 3.4 1 1 2 3 3 3 3 Major Facilitator Superfamily Cation_efflux PF01545.16 GAP88344.1 - 5.7e-36 124.0 6.4 6.7e-36 123.8 4.4 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 GAP88345.1 - 1.3e-46 159.0 4.5 1.6e-46 158.8 3.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Dioxygenase_C PF00775.16 GAP88346.1 - 4.7e-48 162.8 0.0 6.2e-48 162.4 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 GAP88346.1 - 4.6e-11 42.5 0.0 7.3e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Lactonase PF10282.4 GAP88347.1 - 3.4e-17 62.5 0.0 4.3e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF21 PF01595.15 GAP88348.1 - 3e-32 111.3 0.1 4.5e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 GAP88348.1 - 1.9e-05 24.3 0.2 0.15 11.8 0.0 2.8 2 0 0 2 2 2 2 CBS domain SET PF00856.23 GAP88350.1 - 0.0056 16.9 0.0 1.4 9.2 0.0 2.8 2 1 0 2 2 2 1 SET domain Zn_clus PF00172.13 GAP88351.1 - 1.3e-09 37.8 11.7 2.1e-09 37.1 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAP88351.1 - 6.6e-07 28.4 0.0 3.6e-06 26.0 0.0 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Copper-fist PF00649.13 GAP88353.1 - 2.3e-22 77.9 1.6 2.3e-22 77.9 1.1 3.6 2 2 1 3 3 3 1 Copper fist DNA binding domain DUF4160 PF13711.1 GAP88353.1 - 0.015 15.1 0.1 0.042 13.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) ApbA PF02558.11 GAP88355.1 - 9.7e-29 99.7 0.0 1.6e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 GAP88355.1 - 3.3e-25 88.4 0.0 5.6e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal PHY PF00360.15 GAP88356.1 - 2e-29 102.0 0.0 4.3e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 GAP88356.1 - 4.8e-19 68.1 0.7 1e-18 67.0 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAP88356.1 - 8.9e-17 61.1 0.0 4.4e-16 58.8 0.0 2.3 2 1 0 2 2 2 1 Response regulator receiver domain GAF PF01590.21 GAP88356.1 - 8e-16 58.5 0.0 1.9e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 GAF domain HisKA PF00512.20 GAP88356.1 - 3.1e-12 46.2 0.9 8.9e-12 44.8 0.3 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 GAP88356.1 - 2.6e-08 34.2 0.0 6.8e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.1 GAP88356.1 - 0.024 14.2 0.1 0.079 12.6 0.0 1.9 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MFS_1 PF07690.11 GAP88357.1 - 4.3e-34 117.7 24.9 4.3e-34 117.7 17.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Chromo_shadow PF01393.14 GAP88358.1 - 5.3e-14 51.7 0.2 2.4e-12 46.5 0.0 2.5 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.19 GAP88358.1 - 5.2e-12 45.2 0.9 5.2e-12 45.2 0.7 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-Di19 PF05605.7 GAP88359.1 - 0.0098 16.0 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Peptidase_S46 PF10459.4 GAP88359.1 - 0.016 13.6 0.6 0.026 12.9 0.4 1.3 1 0 0 1 1 1 0 Peptidase S46 zf-C2HC_2 PF13913.1 GAP88359.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.21 GAP88359.1 - 0.13 12.6 0.1 0.29 11.5 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-ribbon_3 PF13248.1 GAP88359.1 - 0.13 11.4 0.2 0.25 10.6 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Glyco_hydro_16 PF00722.16 GAP88360.1 - 1.7e-40 138.2 3.0 1.7e-40 138.2 2.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 CytochromB561_N PF09786.4 GAP88360.1 - 4.2 5.6 9.0 5.8 5.2 6.2 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal UPF0547 PF10571.4 GAP88361.1 - 0.025 14.2 0.7 0.76 9.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DUF164 PF02591.10 GAP88361.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative zinc ribbon domain zf-ribbon_3 PF13248.1 GAP88361.1 - 0.19 10.9 1.7 1 8.6 0.1 2.5 3 0 0 3 3 3 0 zinc-ribbon domain Ogr_Delta PF04606.7 GAP88361.1 - 0.44 10.2 2.3 6.2 6.5 0.1 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zinc_ribbon_2 PF13240.1 GAP88361.1 - 0.46 10.0 0.0 0.46 10.0 0.0 2.3 3 0 0 3 3 3 0 zinc-ribbon domain TCO89 PF10452.4 GAP88362.1 - 3.5e-08 32.8 0.3 3.5e-08 32.8 0.2 3.2 2 2 0 2 2 2 1 TORC1 subunit TCO89 Glyco_hydro_16 PF00722.16 GAP88363.1 - 8.5e-14 51.2 1.3 1.1e-13 50.8 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Fungal_trans PF04082.13 GAP88364.1 - 3.1e-23 81.9 0.0 5.1e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyr_redox_2 PF07992.9 GAP88365.1 - 5.6e-14 52.4 0.8 7.7e-08 32.4 0.0 3.2 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAP88365.1 - 3.7e-12 46.4 0.2 7.9e-09 35.8 0.3 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP88365.1 - 8e-08 32.5 0.5 0.0048 16.9 0.0 3.3 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAP88365.1 - 0.00094 18.1 0.0 0.009 14.9 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 GAP88365.1 - 0.015 15.0 0.2 2.3 7.9 0.0 3.5 4 0 0 4 4 4 0 FAD-NAD(P)-binding Abhydrolase_6 PF12697.2 GAP88365.1 - 0.034 14.0 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DAO PF01266.19 GAP88365.1 - 0.038 12.8 8.1 3.2 6.5 0.1 3.9 2 1 1 4 4 4 0 FAD dependent oxidoreductase Abhydrolase_5 PF12695.2 GAP88365.1 - 0.069 12.9 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Dna2 PF08696.6 GAP88367.1 - 6e-70 234.8 0.3 1.3e-69 233.7 0.0 1.7 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.1 GAP88367.1 - 7.6e-52 175.6 0.0 1.7e-51 174.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAP88367.1 - 3e-40 138.2 0.3 7.9e-20 71.4 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 GAP88367.1 - 8e-13 48.4 0.0 2.1e-12 47.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAP88367.1 - 4.1e-11 42.4 0.1 1.1e-10 41.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain Cas_Cas4 PF01930.12 GAP88367.1 - 7e-09 35.8 0.1 9.6e-08 32.1 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.2 GAP88367.1 - 8.2e-07 28.6 0.0 2.5e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.13 GAP88367.1 - 1.3e-05 24.8 0.1 0.97 8.9 0.0 3.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 GAP88367.1 - 0.00013 21.6 0.0 0.00035 20.2 0.0 1.7 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.16 GAP88367.1 - 0.00024 20.5 0.0 0.00052 19.4 0.0 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.1 GAP88367.1 - 0.0024 17.8 0.0 0.0083 16.1 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.17 GAP88367.1 - 0.0026 17.2 0.2 0.0052 16.2 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain MobB PF03205.9 GAP88367.1 - 0.0041 16.8 0.0 0.0093 15.6 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B PIF1 PF05970.9 GAP88367.1 - 0.0045 15.9 0.1 0.092 11.6 0.1 2.3 2 0 0 2 2 2 1 PIF1-like helicase CbiA PF01656.18 GAP88367.1 - 0.005 16.2 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.1 GAP88367.1 - 0.02 14.2 0.0 0.054 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 GAP88367.1 - 0.021 13.7 0.2 0.037 12.9 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RuvB_N PF05496.7 GAP88367.1 - 0.021 13.8 0.0 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 GAP88367.1 - 0.06 13.4 0.2 0.56 10.3 0.1 2.8 2 1 0 2 2 1 0 AAA domain AAA_10 PF12846.2 GAP88367.1 - 0.061 12.7 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain DUF87 PF01935.12 GAP88367.1 - 0.087 12.6 0.2 0.23 11.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF2075 PF09848.4 GAP88367.1 - 0.094 11.6 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ArgK PF03308.11 GAP88367.1 - 0.096 11.4 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA PF00004.24 GAP88367.1 - 0.1 12.7 0.1 0.29 11.3 0.1 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsJ PF01728.14 GAP88368.1 - 1e-61 208.0 0.0 1.4e-61 207.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase DEAD PF00270.24 GAP88369.1 - 1.1e-41 142.1 0.0 3.1e-41 140.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP88369.1 - 1.4e-22 79.3 0.1 4.8e-22 77.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 GAP88369.1 - 1.4e-05 24.1 0.0 2.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain MACPF PF01823.14 GAP88369.1 - 0.012 15.3 1.1 0.022 14.4 0.8 1.4 1 0 0 1 1 1 0 MAC/Perforin domain DUF3290 PF11694.3 GAP88369.1 - 0.15 11.7 0.0 0.53 9.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Methyltransf_11 PF08241.7 GAP88370.1 - 6.3e-09 36.2 0.0 1.3e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP88370.1 - 1.3e-07 31.5 0.0 1.8e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP88370.1 - 2e-05 24.9 0.0 9.8e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP88370.1 - 2.2e-05 24.8 0.0 3.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP88370.1 - 3.3e-05 23.1 0.0 5.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Peptidase_C37 PF05416.7 GAP88370.1 - 0.037 12.3 0.3 0.075 11.3 0.0 1.5 2 0 0 2 2 2 0 Southampton virus-type processing peptidase NNMT_PNMT_TEMT PF01234.12 GAP88370.1 - 0.047 12.6 0.0 6.7 5.6 0.0 2.2 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family A_deaminase PF00962.17 GAP88374.1 - 3.2e-43 147.9 0.3 2.2e-40 138.6 0.0 2.7 2 1 0 2 2 2 2 Adenosine/AMP deaminase SRP40_C PF05022.7 GAP88375.1 - 1.3e-24 86.4 0.8 3.6e-24 85.0 0.5 1.8 1 0 0 1 1 1 1 SRP40, C-terminal domain DUF3649 PF12365.3 GAP88376.1 - 0.0074 15.7 3.1 0.0074 15.7 2.1 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF3649) DUF2157 PF09925.4 GAP88376.1 - 0.96 9.0 7.8 0.34 10.4 2.8 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) ArsB PF02040.10 GAP88377.1 - 4.2e-14 52.3 21.6 4.4e-07 29.2 6.0 2.3 2 0 0 2 2 2 2 Arsenical pump membrane protein DUF2730 PF10805.3 GAP88377.1 - 0.14 11.8 0.5 13 5.5 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Complex1_51K PF01512.12 GAP88379.1 - 1.6e-46 157.8 0.0 2.6e-46 157.1 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 GAP88379.1 - 2.7e-17 61.6 0.7 2.7e-17 61.6 0.5 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 GAP88379.1 - 3.3e-09 36.5 0.1 1.1e-08 34.8 0.0 2.0 2 0 0 2 2 2 1 SLBB domain Hexapep PF00132.19 GAP88380.1 - 7.1e-09 34.7 11.5 7.9e-07 28.3 1.5 3.5 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 GAP88380.1 - 0.00098 18.6 9.3 1.7 8.2 0.1 3.5 2 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase p450 PF00067.17 GAP88381.1 - 7.2e-57 192.9 0.0 1e-56 192.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Band_7 PF01145.20 GAP88382.1 - 7.8e-32 110.6 0.6 1.2e-31 109.9 0.4 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 GAP88382.1 - 0.024 14.1 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family GSH-S_N PF02951.9 GAP88382.1 - 0.11 12.2 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain Sec7_N PF12783.2 GAP88383.1 - 5e-33 113.8 0.4 1.8e-30 105.6 0.0 3.6 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 GAP88383.1 - 2e-06 27.2 0.1 0.00041 19.7 0.0 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) Ceramidase_alk PF04734.8 GAP88384.1 - 2.2e-273 908.2 0.1 2.5e-273 908.0 0.1 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Nrf1_DNA-bind PF10491.4 GAP88385.1 - 0.11 11.6 0.1 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 DNA_pol3_delt_C PF14840.1 GAP88385.1 - 0.12 12.4 0.3 0.15 12.1 0.2 1.1 1 0 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term Glucosamine_iso PF01182.15 GAP88386.1 - 2.1e-24 86.3 0.0 3.1e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Hexokinase_1 PF00349.16 GAP88387.1 - 5.5e-34 117.2 0.0 7.4e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 GAP88387.1 - 2.7e-19 69.3 0.0 3.8e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase NDT80_PhoG PF05224.7 GAP88388.1 - 8.9e-34 117.1 0.0 1.9e-33 116.0 0.0 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Glyco_hydro_3 PF00933.16 GAP88389.1 - 2.3e-54 184.4 0.0 3.4e-54 183.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.19 GAP88389.1 - 0.0014 18.6 0.0 0.0046 16.9 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAP88389.1 - 0.015 15.4 0.0 0.043 13.9 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.17 GAP88389.1 - 0.027 13.9 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Amidohydro_4 PF13147.1 GAP88390.1 - 7.6e-15 55.6 0.1 1.4e-06 28.5 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 GAP88390.1 - 1.6e-09 37.8 0.1 1.5e-08 34.7 0.1 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 GAP88390.1 - 1.2e-08 34.6 0.0 3.8e-08 32.9 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 GAP88390.1 - 0.0021 17.8 0.0 0.0054 16.5 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase UvrD_C PF13361.1 GAP88391.1 - 1.6e-80 271.1 0.0 2.3e-80 270.6 0.0 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 GAP88391.1 - 2.3e-64 217.7 0.1 4.5e-62 210.1 0.1 2.4 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 GAP88391.1 - 1.6e-14 53.8 0.0 6.1e-14 52.0 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 GAP88391.1 - 1.1e-11 44.2 0.2 1.1e-11 44.2 0.1 2.9 3 0 0 3 3 3 1 Part of AAA domain Viral_helicase1 PF01443.13 GAP88391.1 - 2.8e-06 27.0 0.0 0.23 10.9 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.1 GAP88391.1 - 0.0013 18.1 0.0 0.0031 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 GAP88391.1 - 0.0049 16.4 0.1 0.0049 16.4 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.1 GAP88391.1 - 0.0058 16.2 0.0 0.019 14.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF2014 PF09427.5 GAP88393.1 - 9.1e-97 323.2 7.0 1.4e-96 322.6 4.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 GAP88393.1 - 2.6e-17 62.2 0.8 5.5e-17 61.2 0.5 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CIA30 PF08547.7 GAP88394.1 - 1.7e-35 122.1 0.0 2.1e-35 121.9 0.0 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) bZIP_1 PF00170.16 GAP88395.1 - 7.9e-05 22.5 6.6 0.00015 21.6 4.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAP88395.1 - 0.0018 18.0 7.0 0.0032 17.2 4.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 GAP88395.1 - 5.9 7.2 11.6 32 4.9 7.4 2.0 1 1 1 2 2 2 0 bZIP Maf transcription factor Na_H_Exchanger PF00999.16 GAP88396.1 - 1.9e-71 240.6 44.8 2.6e-71 240.1 31.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Methyltransf_23 PF13489.1 GAP88397.1 - 5.3e-18 65.2 0.0 7.4e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP88397.1 - 3.6e-08 33.9 0.0 4.1e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP88397.1 - 4.9e-08 33.3 0.0 8.4e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP88397.1 - 7.9e-07 28.7 0.0 7.1e-06 25.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP88397.1 - 5.2e-06 26.8 0.0 1.9e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP88397.1 - 0.0061 16.9 0.0 0.022 15.1 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAP88397.1 - 0.049 12.6 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_26 PF13659.1 GAP88397.1 - 0.056 13.4 0.0 0.18 11.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 GAP88397.1 - 0.06 12.9 0.0 0.088 12.3 0.0 1.5 1 1 0 1 1 1 0 Met-10+ like-protein Lustrin_cystein PF14625.1 GAP88398.1 - 0.00051 20.0 6.9 0.0011 19.0 1.7 2.5 2 0 0 2 2 2 1 Lustrin, cysteine-rich repeated domain zf-CCCH PF00642.19 GAP88398.1 - 0.0088 15.6 0.7 0.48 10.1 0.1 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Rcd1 PF04078.8 GAP88399.1 - 1.8e-130 433.4 2.6 2.1e-130 433.2 1.8 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Pkinase PF00069.20 GAP88400.1 - 8.2e-74 248.0 0.0 8.2e-74 248.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP88400.1 - 5.4e-38 130.5 0.0 1.3e-37 129.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 GAP88400.1 - 3.6e-17 61.5 0.2 5.9e-17 60.8 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 GAP88400.1 - 8.4e-06 24.9 0.1 1.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 GAP88400.1 - 0.00013 21.0 0.0 0.00023 20.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 GAP88400.1 - 0.019 14.2 0.0 0.05 12.9 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 GAP88400.1 - 0.023 14.0 0.0 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family WaaY PF06176.6 GAP88400.1 - 0.26 10.4 0.1 0.44 9.7 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Med13_C PF06333.7 GAP88401.1 - 9.9e-102 340.6 0.2 3e-101 339.0 0.0 1.9 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 GAP88401.1 - 1.6e-17 63.3 0.0 5.4e-17 61.5 0.0 1.9 1 1 0 1 1 1 1 Mediator complex subunit 13 N-terminal NUC153 PF08159.7 GAP88402.1 - 1.4e-13 50.1 2.7 3.2e-13 49.0 1.9 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 GAP88402.1 - 7.5e-05 22.4 0.0 0.00095 18.9 0.0 2.6 3 0 0 3 3 3 1 WD domain, G-beta repeat Pyridox_ox_2 PF12900.2 GAP88405.1 - 2.6e-34 118.1 0.0 4.8e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Glyco_hydro_47 PF01532.15 GAP88406.1 - 1.1e-130 436.4 0.0 1.2e-130 436.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Rad10 PF03834.9 GAP88407.1 - 1.2e-30 105.0 0.0 1.8e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 GAP88407.1 - 0.0016 18.6 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain Methyltransf_26 PF13659.1 GAP88408.1 - 2.3e-06 27.6 0.0 5.3e-05 23.2 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Spermine_synth PF01564.12 GAP88408.1 - 1.4e-05 24.1 0.0 2.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 GAP88408.1 - 0.00069 20.1 0.0 0.0029 18.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP88408.1 - 0.076 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_M35 PF02102.10 GAP88410.1 - 1e-91 307.2 19.1 1.3e-91 306.9 13.2 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 GAP88410.1 - 5.8e-10 39.8 1.6 1e-09 39.0 0.2 2.0 1 1 0 2 2 2 1 Lysine-specific metallo-endopeptidase DUF462 PF04315.7 GAP88410.1 - 0.099 12.0 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF462 adh_short PF00106.20 GAP88412.1 - 4.4e-12 46.2 0.2 5.6e-12 45.8 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP88412.1 - 0.00017 21.3 0.2 0.00023 20.8 0.1 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 GAP88412.1 - 0.0038 16.9 1.4 0.0069 16.1 0.4 1.9 1 1 1 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Alba PF01918.16 GAP88412.1 - 0.011 15.3 0.0 0.057 13.0 0.0 1.9 2 0 0 2 2 2 0 Alba HAD PF12710.2 GAP88412.1 - 0.018 15.1 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Epimerase PF01370.16 GAP88412.1 - 0.034 13.5 0.1 0.044 13.2 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 GAP88412.1 - 0.038 13.7 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_2 PF03446.10 GAP88412.1 - 0.038 13.8 0.2 0.097 12.5 0.1 1.6 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase THF_DHG_CYH_C PF02882.14 GAP88412.1 - 0.043 12.8 0.0 0.049 12.6 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HHH_5 PF14520.1 GAP88412.1 - 0.05 13.7 0.2 0.32 11.2 0.1 2.1 1 1 0 1 1 1 0 Helix-hairpin-helix domain ATP_bind_2 PF03668.10 GAP88412.1 - 0.062 12.3 0.1 0.08 12.0 0.0 1.1 1 0 0 1 1 1 0 P-loop ATPase protein family adh_short_C2 PF13561.1 GAP88413.1 - 1.2e-07 31.7 0.1 1.4e-07 31.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAP88413.1 - 0.0091 15.9 0.4 0.015 15.2 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase FBPase PF00316.15 GAP88415.1 - 1.6e-122 408.4 0.0 1.8e-122 408.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Sec3_C PF09763.4 GAP88416.1 - 3e-232 772.6 3.0 3.9e-232 772.3 2.1 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 GAP88416.1 - 4.7e-31 106.5 0.0 1e-30 105.4 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.1 GAP88416.1 - 6.8e-05 22.9 1.3 0.00084 19.4 0.0 2.6 2 0 0 2 2 2 1 Sec3 exocyst complex subunit DUF2408 PF10303.4 GAP88416.1 - 0.0094 16.0 0.3 1.6 8.8 0.2 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2408) Vps52 PF04129.7 GAP88416.1 - 0.019 13.5 1.3 0.77 8.2 0.1 2.2 2 0 0 2 2 2 0 Vps52 / Sac2 family Peptidase_S58 PF03576.9 GAP88417.1 - 8.4e-115 383.4 0.2 9.6e-115 383.2 0.1 1.0 1 0 0 1 1 1 1 Peptidase family S58 Fe-ADH PF00465.14 GAP88418.1 - 9e-104 347.0 0.1 1.2e-103 346.6 0.1 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 GAP88418.1 - 8.9e-16 57.9 0.0 1.6e-13 50.5 0.1 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 GAP88418.1 - 0.00029 20.2 0.1 0.0005 19.5 0.1 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Methyltransf_11 PF08241.7 GAP88419.1 - 3.6e-09 36.9 0.0 9.9e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP88419.1 - 5.2e-08 33.1 0.0 9.8e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP88419.1 - 6e-08 32.4 0.0 9.1e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP88419.1 - 7.9e-06 25.1 0.0 1e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 GAP88419.1 - 1.3e-05 25.0 0.0 2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP88419.1 - 3.7e-05 24.2 0.1 0.00018 22.0 0.1 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP88419.1 - 0.00011 22.6 0.0 0.00024 21.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP88419.1 - 0.00032 20.7 2.5 0.00081 19.4 1.7 1.7 1 0 0 1 1 1 1 Methyltransferase domain Sugar_tr PF00083.19 GAP88421.1 - 3.9e-59 200.4 11.2 4.7e-59 200.1 7.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP88421.1 - 8.3e-34 116.8 16.4 1.2e-33 116.3 11.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 GAP88421.1 - 4.6e-06 25.3 4.3 4.6e-06 25.3 3.0 2.6 2 1 1 3 3 3 1 MFS/sugar transport protein TRI12 PF06609.8 GAP88421.1 - 0.0012 17.1 7.4 0.002 16.3 2.8 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 GAP88421.1 - 0.025 12.7 2.7 0.037 12.1 1.9 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector Cytochrome-c551 PF10643.4 GAP88421.1 - 0.084 12.1 1.6 0.25 10.6 0.5 2.0 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 Sugar_tr PF00083.19 GAP88422.1 - 7.5e-09 34.6 0.8 8.4e-09 34.5 0.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Terpene_synth_C PF03936.11 GAP88424.1 - 1.4e-16 60.5 0.0 5e-16 58.7 0.0 1.7 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain Caps_synth PF05704.7 GAP88425.1 - 1e-12 47.7 0.0 2.1e-12 46.7 0.0 1.4 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 GAP88425.1 - 0.0011 19.2 0.0 0.0021 18.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif p450 PF00067.17 GAP88426.1 - 5.8e-39 133.8 0.0 8e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Asparaginase_2 PF01112.13 GAP88427.1 - 7.5e-41 139.8 1.8 8.2e-21 74.0 0.0 3.5 3 1 0 3 3 3 3 Asparaginase Peptidase_M20 PF01546.23 GAP88428.1 - 3.2e-20 72.4 0.0 1.2e-19 70.5 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 GAP88428.1 - 2e-14 52.8 5.5 0.014 15.2 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat M20_dimer PF07687.9 GAP88428.1 - 1.3e-08 34.5 0.0 2.2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 GAP88428.1 - 0.023 14.4 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 Zip PF02535.17 GAP88429.1 - 0.0021 17.1 5.5 0.0032 16.5 3.8 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter FAM176 PF14851.1 GAP88431.1 - 4.2 7.0 10.1 0.9 9.2 0.3 2.2 2 0 0 2 2 2 0 FAM176 family PI-PLC-X PF00388.14 GAP88433.1 - 1.4e-63 212.6 0.0 2.4e-63 211.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 GAP88433.1 - 1.4e-37 128.2 0.0 2.8e-37 127.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 GAP88433.1 - 0.00064 19.5 0.1 0.0038 17.0 0.0 2.2 2 0 0 2 2 2 1 C2 domain EF-hand_like PF09279.6 GAP88433.1 - 0.026 14.5 0.0 0.27 11.2 0.0 2.3 1 1 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like Lactamase_B_2 PF12706.2 GAP88434.1 - 2.2e-09 37.1 0.0 5.2e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.9 GAP88434.1 - 3e-05 23.9 0.0 8e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.22 GAP88434.1 - 0.00039 20.1 0.0 0.00088 18.9 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Pkinase PF00069.20 GAP88437.1 - 1.7e-13 50.3 0.0 1.6e-06 27.4 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 GAP88437.1 - 0.0068 15.5 0.2 0.58 9.1 0.1 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase UxaC PF02614.9 GAP88437.1 - 0.064 11.8 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Glucuronate isomerase MFS_1 PF07690.11 GAP88438.1 - 1.8e-12 46.6 34.2 3.2e-10 39.2 14.2 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF3975 PF13126.1 GAP88438.1 - 0.1 12.7 1.7 3.9 7.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3975) DUF2456 PF10445.4 GAP88439.1 - 7.9e-14 51.3 1.3 1.8e-13 50.2 0.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2456) TrkH PF02386.11 GAP88439.1 - 0.0089 14.6 0.6 0.0089 14.6 0.4 1.9 2 0 0 2 2 2 1 Cation transport protein Rab5ip PF07019.7 GAP88439.1 - 0.89 9.7 7.6 2.4 8.3 0.9 2.4 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) DUF1049 PF06305.6 GAP88439.1 - 4.2 6.9 6.1 1.5 8.3 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) YrvL PF14184.1 GAP88439.1 - 6.1 6.6 9.2 0.15 11.9 0.3 2.4 3 0 0 3 3 3 0 Regulatory protein YrvL DUF4401 PF14351.1 GAP88439.1 - 7.1 5.5 10.1 0.42 9.5 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4401) Aldedh PF00171.17 GAP88440.1 - 2.3e-139 464.7 0.0 2.9e-139 464.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAP88440.1 - 0.0048 15.6 0.0 0.0079 14.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) HET PF06985.6 GAP88441.1 - 1.9e-22 79.9 0.0 3e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.17 GAP88442.1 - 6.1e-49 166.7 0.0 8.1e-49 166.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 GAP88443.1 - 0.0041 15.6 0.0 0.0047 15.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Uso1_p115_head PF04869.9 GAP88443.1 - 0.069 11.9 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, head region DUF3593 PF12159.3 GAP88443.1 - 0.1 12.3 0.2 0.22 11.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3593) Flagellin_C PF00700.16 GAP88444.1 - 0.064 13.4 0.1 0.37 10.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region adh_short_C2 PF13561.1 GAP88445.1 - 2.1e-18 66.9 0.0 2.6e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAP88445.1 - 3.5e-17 62.8 1.0 4.7e-17 62.3 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 GAP88445.1 - 0.00025 20.4 0.0 0.00037 19.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family ADH_zinc_N PF00107.21 GAP88445.1 - 0.00031 20.2 0.0 0.00071 19.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF1776 PF08643.5 GAP88445.1 - 0.0013 17.9 0.0 0.11 11.6 0.0 2.1 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 GAP88445.1 - 0.0039 16.6 0.0 0.026 13.9 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAP88445.1 - 0.0075 16.2 0.2 0.022 14.7 0.1 1.9 2 1 0 2 2 2 1 NADH(P)-binding 2-Hacid_dh_C PF02826.14 GAP88445.1 - 0.019 14.1 0.0 0.044 12.9 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 GAP88445.1 - 0.024 14.5 0.0 0.065 13.0 0.0 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 GAP88445.1 - 0.026 14.2 0.0 0.048 13.3 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 GAP88445.1 - 0.032 14.6 0.1 0.12 12.7 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 GAP88445.1 - 0.062 12.7 0.0 0.097 12.1 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RmlD_sub_bind PF04321.12 GAP88445.1 - 0.083 11.7 0.0 0.22 10.3 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain TrkA_N PF02254.13 GAP88445.1 - 0.09 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain MFS_1 PF07690.11 GAP88446.1 - 6.7e-37 127.0 46.4 6.7e-37 127.0 32.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAP88446.1 - 2e-14 52.7 26.3 2.9e-14 52.1 18.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.20 GAP88447.1 - 1.6e-14 54.1 0.1 2.5e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP88447.1 - 1.5e-05 24.7 0.3 2.7e-05 23.9 0.0 1.5 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 GAP88448.1 - 6.3e-12 45.7 0.4 6.7e-11 42.3 0.2 2.4 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP88448.1 - 7.6e-07 29.1 0.0 1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP88448.1 - 2.1e-06 27.5 0.0 3.9e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 GAP88448.1 - 5.3e-05 22.7 0.1 0.00016 21.1 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family FAD_binding_4 PF01565.18 GAP88449.1 - 8.2e-21 73.9 3.8 1.4e-20 73.1 2.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP88449.1 - 1.1e-06 28.4 0.0 2.3e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cupin_2 PF07883.6 GAP88450.1 - 2.8e-06 26.7 0.1 4.6e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Cupin domain adh_short PF00106.20 GAP88451.1 - 3e-17 63.0 0.1 5e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP88451.1 - 6.1e-09 35.7 0.0 1.1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAP88451.1 - 0.0033 17.2 0.0 0.0086 15.8 0.0 1.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 GAP88451.1 - 0.08 11.8 0.0 0.16 10.8 0.0 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein FAD_binding_4 PF01565.18 GAP88452.1 - 2.3e-23 82.2 0.1 4.8e-23 81.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP88452.1 - 8.7e-10 38.3 0.5 2.2e-09 37.0 0.3 1.7 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.20 GAP88453.1 - 1.7e-21 76.8 0.0 2.2e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP88453.1 - 4.6e-13 49.4 0.0 5.9e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAP88453.1 - 0.0016 18.5 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAP88453.1 - 0.069 12.5 0.2 0.12 11.7 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Cupin_2 PF07883.6 GAP88454.1 - 3e-07 29.8 0.5 2.5e-06 26.9 0.0 2.5 2 1 1 3 3 3 1 Cupin domain adh_short_C2 PF13561.1 GAP88455.1 - 6e-26 91.6 0.1 7.6e-26 91.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAP88455.1 - 5.1e-18 65.5 2.0 8.6e-18 64.7 1.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP88455.1 - 1.7e-08 34.3 0.5 5.2e-08 32.7 0.4 1.7 1 1 0 1 1 1 1 KR domain ketoacyl-synt PF00109.21 GAP88456.1 - 2.2e-69 233.7 0.0 5.7e-69 232.4 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 GAP88456.1 - 6.8e-54 182.2 0.1 1.6e-53 181.0 0.1 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 GAP88456.1 - 4.3e-53 180.7 0.6 7e-53 180.0 0.4 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 GAP88456.1 - 2.8e-51 174.4 0.0 4.5e-51 173.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 GAP88456.1 - 4.1e-43 147.1 1.5 8.1e-43 146.2 0.1 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAP88456.1 - 1.2e-36 125.0 0.1 1.2e-36 125.0 0.1 3.0 4 0 0 4 4 4 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 GAP88456.1 - 2.2e-18 66.0 0.3 8.8e-18 64.1 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAP88456.1 - 4.2e-13 50.2 0.0 5.8e-12 46.6 0.0 3.1 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP88456.1 - 5e-06 26.2 0.0 1.3e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 GAP88456.1 - 0.00049 19.1 0.0 0.001 18.1 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 GAP88456.1 - 0.011 15.3 0.1 0.034 13.8 0.1 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Glyco_hydro_61 PF03443.9 GAP88457.1 - 3.3e-65 219.9 0.0 4.2e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Lipase_GDSL PF00657.17 GAP88458.1 - 4.2e-14 52.9 0.5 7.1e-14 52.1 0.4 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 GAP88458.1 - 3.6e-12 46.7 0.1 1.2e-11 45.0 0.0 1.9 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 GAP88458.1 - 0.025 14.3 0.0 0.057 13.1 0.0 1.6 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family UPF0004 PF00919.15 GAP88459.1 - 0.028 14.2 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein family UPF0004 DUF2795 PF11387.3 GAP88459.1 - 0.1 12.4 0.0 2.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2795) FXa_inhibition PF14670.1 GAP88460.1 - 0.026 14.6 3.2 0.31 11.1 0.2 2.5 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site Period_C PF12114.3 GAP88461.1 - 6.4 6.3 13.2 9.9 5.7 9.2 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Macoilin PF09726.4 GAP88461.1 - 7.1 4.7 11.0 9.1 4.4 7.7 1.1 1 0 0 1 1 1 0 Transmembrane protein SBDS_C PF09377.5 GAP88462.1 - 1.1e-51 173.7 0.2 1.6e-51 173.2 0.2 1.2 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 GAP88462.1 - 2.2e-28 97.8 0.1 4e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Ribosomal_60s PF00428.14 GAP88462.1 - 1.2 9.5 15.1 0.41 11.0 4.2 3.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein Peptidase_S10 PF00450.17 GAP88463.1 - 3e-131 438.4 4.2 3.7e-131 438.1 2.9 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 GAP88463.1 - 0.00027 20.9 0.0 0.011 15.5 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Carbpep_Y_N PF05388.6 GAP88463.1 - 0.0003 20.9 0.0 0.00056 20.0 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide SVS_QK PF10578.4 GAP88463.1 - 0.18 12.1 1.6 0.51 10.7 1.1 1.7 1 0 0 1 1 1 0 Seminal vesicle protein repeat Methyltransf_31 PF13847.1 GAP88464.1 - 8.3e-10 38.4 0.0 1.1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP88464.1 - 2.6e-09 37.4 0.0 4.6e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP88464.1 - 2.5e-05 24.8 0.0 3.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP88464.1 - 0.0011 19.4 0.0 0.0018 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP88464.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 GAP88464.1 - 0.018 15.0 0.0 0.035 14.1 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Cas1_AcylT PF07779.7 GAP88465.1 - 8.1e-82 275.2 18.2 3.8e-81 273.0 8.1 2.9 1 1 1 2 2 2 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.1 GAP88465.1 - 9.6e-24 84.6 0.0 1.4e-23 84.0 0.0 1.3 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Mitofilin PF09731.4 GAP88466.1 - 0.0019 16.9 0.0 0.0026 16.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Arf PF00025.16 GAP88467.1 - 1.2e-40 138.5 0.0 1.8e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 GAP88467.1 - 1.3e-14 53.6 0.0 2.7e-10 39.4 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 GAP88467.1 - 2.2e-08 33.6 0.0 6.8e-08 32.0 0.0 1.7 1 1 0 1 1 1 1 Ras family SRPRB PF09439.5 GAP88467.1 - 1.3e-07 31.0 0.0 2.8e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 GAP88467.1 - 2.9e-07 29.8 0.0 3.3e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAP88467.1 - 2.8e-05 23.6 0.0 7.1e-05 22.3 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 GAP88467.1 - 0.00013 22.4 0.0 0.00086 19.8 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 GAP88467.1 - 0.0085 16.0 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNase_PH PF01138.16 GAP88468.1 - 3.7e-24 85.5 0.0 6.3e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 GAP88468.1 - 1.3e-07 31.4 0.0 2.7e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 ATP_transf PF09830.4 GAP88469.1 - 1.8e-17 62.8 0.0 3.2e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase Myb_DNA-bind_4 PF13837.1 GAP88470.1 - 0.0069 16.4 0.1 0.017 15.2 0.1 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Integrase_DNA PF02920.10 GAP88470.1 - 0.024 14.0 0.3 0.07 12.5 0.2 1.8 1 0 0 1 1 1 0 DNA binding domain of tn916 integrase McyA_C PF12593.3 GAP88470.1 - 0.72 9.6 3.4 14 5.4 0.3 2.6 2 0 0 2 2 2 0 Microcystin synthetase C terminal GATase PF00117.23 GAP88471.1 - 1.3e-08 34.5 0.0 1.8e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NPP1 PF05630.6 GAP88473.1 - 1.9e-79 266.2 0.8 2.2e-79 266.0 0.6 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) EBP PF05241.7 GAP88475.1 - 1.7e-06 27.2 2.8 2.5e-06 26.6 2.0 1.2 1 0 0 1 1 1 1 Emopamil binding protein Dynactin_p62 PF05502.8 GAP88477.1 - 3e-143 478.1 0.7 6.3e-143 477.0 0.5 1.5 1 1 0 1 1 1 1 Dynactin p62 family Ribosomal_S7e PF01251.13 GAP88478.1 - 5.3e-82 273.9 0.2 6e-82 273.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e ADH_N PF08240.7 GAP88479.1 - 3.3e-26 91.1 3.5 5.1e-26 90.5 2.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAP88479.1 - 2.3e-14 53.0 0.0 4.3e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 GAP88479.1 - 0.058 12.5 0.1 0.1 11.7 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1349 PF07081.6 GAP88481.1 - 8.5e-13 48.0 0.0 1.2e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) MFS_1 PF07690.11 GAP88482.1 - 5.4e-11 41.8 44.5 5.4e-11 41.8 30.9 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily AA_permease PF00324.16 GAP88483.1 - 2.8e-136 454.6 38.9 3.4e-136 454.3 27.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAP88483.1 - 1.5e-42 145.6 41.0 2.1e-42 145.1 28.4 1.0 1 0 0 1 1 1 1 Amino acid permease Orai-1 PF07856.7 GAP88483.1 - 3.8 7.0 11.3 0.33 10.5 3.4 2.1 2 0 0 2 2 2 0 Mediator of CRAC channel activity Dynamin_N PF00350.18 GAP88484.1 - 2.4e-12 46.9 0.0 1.2e-11 44.6 0.0 2.2 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 GAP88484.1 - 1.3e-05 25.1 0.2 0.0003 20.7 0.1 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase OprB PF04966.7 GAP88484.1 - 0.00014 21.1 0.0 0.00084 18.5 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate-selective porin, OprB family Miro PF08477.8 GAP88484.1 - 0.00035 21.0 0.0 0.0059 17.0 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein ABC_tran PF00005.22 GAP88484.1 - 0.00053 20.3 3.7 0.0013 19.0 0.0 3.3 4 0 0 4 4 4 1 ABC transporter DUF258 PF03193.11 GAP88484.1 - 0.0013 17.9 0.0 0.0049 16.0 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function, DUF258 PIGA PF08288.7 GAP88484.1 - 0.066 13.5 0.1 0.34 11.3 0.0 2.1 2 0 0 2 2 2 0 PIGA (GPI anchor biosynthesis) NUDIX_2 PF13869.1 GAP88485.1 - 8.3e-77 256.7 0.0 1.2e-60 204.0 0.0 2.1 1 1 1 2 2 2 2 Nucleotide hydrolase UPF0047 PF01894.12 GAP88486.1 - 7.3e-40 135.4 0.0 1e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 zf-CHCC PF10276.4 GAP88486.1 - 6e-15 54.7 0.6 9.9e-15 54.1 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.14 GAP88486.1 - 0.085 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb zf-CCHC PF00098.18 GAP88487.1 - 0.0003 20.5 2.7 0.00045 20.0 1.9 1.3 1 0 0 1 1 1 1 Zinc knuckle SR-25 PF10500.4 GAP88487.1 - 1.6 8.1 38.3 2.5 7.5 0.4 2.8 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.9 GAP88487.1 - 2.9 5.8 9.8 3.8 5.4 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein RAP1 PF07218.6 GAP88487.1 - 4.1 5.3 12.1 6.4 4.7 8.4 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FancD2 PF14631.1 GAP88487.1 - 5.7 3.9 5.3 7.4 3.5 3.6 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Peptidase_M16_C PF05193.16 GAP88488.1 - 8.1e-31 107.1 3.1 1.3e-18 67.2 0.0 3.9 6 0 0 6 6 6 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 GAP88488.1 - 5.6e-30 104.0 3.2 7.8e-30 103.6 0.3 2.6 2 1 1 3 3 3 1 Insulinase (Peptidase family M16) UCH PF00443.24 GAP88489.1 - 3.1e-77 259.3 0.0 1.3e-76 257.2 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAP88489.1 - 5.7e-21 75.2 0.0 2e-12 47.1 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 GAP88489.1 - 0.00023 21.5 0.0 0.00069 19.9 0.0 1.9 1 0 0 1 1 1 1 DUSP domain ubiquitin PF00240.18 GAP88489.1 - 0.017 14.5 0.0 0.038 13.3 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family PDEase_I PF00233.14 GAP88490.1 - 1.6e-46 158.9 0.3 1.4e-42 146.0 0.0 2.2 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Pkinase PF00069.20 GAP88491.1 - 2.4e-58 197.3 0.0 3.3e-58 196.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP88491.1 - 7.4e-21 74.3 0.0 1.2e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP88491.1 - 3.7e-07 29.3 0.0 7e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAP88491.1 - 0.00056 19.0 0.1 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAP88491.1 - 0.0023 17.6 0.3 0.06 13.0 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 GAP88491.1 - 0.003 16.9 0.4 0.0059 15.9 0.1 1.5 2 0 0 2 2 2 1 RIO1 family PAS_9 PF13426.1 GAP88491.1 - 0.072 13.4 0.0 3.4 8.1 0.0 3.1 3 1 0 3 3 3 0 PAS domain pKID PF02173.12 GAP88491.1 - 0.074 12.3 0.0 0.074 12.3 0.0 2.0 2 0 0 2 2 2 0 pKID domain Seadorna_VP7 PF07387.6 GAP88491.1 - 0.18 10.5 0.1 0.3 9.8 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RabGAP-TBC PF00566.13 GAP88492.1 - 1.1e-27 96.9 0.1 1.9e-27 96.1 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain KH_1 PF00013.24 GAP88494.1 - 3.2e-39 132.3 9.4 8.1e-15 54.2 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 GAP88494.1 - 6.4e-30 102.2 12.3 4.3e-11 42.1 0.5 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 GAP88494.1 - 8.4e-10 38.0 8.5 0.011 15.2 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 GAP88494.1 - 2.2e-07 30.3 4.1 0.18 11.4 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 GAP88494.1 - 0.00034 20.3 4.7 0.75 9.6 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 GAP88494.1 - 0.00091 18.6 0.4 0.21 11.0 0.0 3.2 3 0 0 3 3 3 1 dUTPase UAA PF08449.6 GAP88495.1 - 1.1e-67 228.0 8.4 5e-67 225.9 5.8 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 GAP88495.1 - 3.4e-09 36.8 20.4 5.2e-07 29.7 1.8 2.9 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 GAP88495.1 - 1.9e-05 24.8 18.2 3.5e-05 23.9 3.7 2.9 2 1 1 3 3 3 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 GAP88495.1 - 0.00071 18.7 4.5 0.023 13.8 0.5 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.11 GAP88495.1 - 0.0012 18.5 7.7 0.0012 18.5 5.3 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family DSPc PF00782.15 GAP88496.1 - 4.5e-23 81.2 0.1 1.1e-21 76.7 0.1 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAP88496.1 - 0.013 14.8 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTS_2-RNA PF01885.11 GAP88498.1 - 4.2e-28 97.9 0.0 5.7e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Neuro_bHLH PF12533.3 GAP88499.1 - 0.057 14.2 8.8 0.13 13.0 6.1 1.5 1 0 0 1 1 1 0 Neuronal helix-loop-helix transcription factor DUF2361 PF10153.4 GAP88500.1 - 4.7e-32 110.5 9.0 8.7e-32 109.6 6.3 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2361) Herpes_IE2_3 PF03361.9 GAP88500.1 - 0.017 14.4 0.2 0.055 12.7 0.4 1.6 2 0 0 2 2 2 0 Herpes virus intermediate/early protein 2/3 She9_MDM33 PF05546.6 GAP88500.1 - 0.06 12.8 3.9 0.095 12.2 2.7 1.2 1 0 0 1 1 1 0 She9 / Mdm33 family CCDC-167 PF15188.1 GAP88500.1 - 5.5 7.0 7.3 0.8 9.6 0.4 2.3 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 zf-RING_2 PF13639.1 GAP88501.1 - 1.3 8.9 11.7 0.65 9.8 5.1 2.7 2 1 0 2 2 2 0 Ring finger domain GRP PF07172.6 GAP88502.1 - 1.7 9.2 21.5 0.058 13.8 4.6 3.0 3 0 0 3 3 3 0 Glycine rich protein family ERF PF04404.7 GAP88502.1 - 3 7.3 6.7 6.9 6.1 4.7 1.5 1 0 0 1 1 1 0 ERF superfamily DUF4611 PF15387.1 GAP88502.1 - 4.6 7.4 9.5 3.1 8.0 3.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) RestrictionSfiI PF11487.3 GAP88503.1 - 0.025 13.7 0.1 0.033 13.3 0.0 1.1 1 0 0 1 1 1 0 Type II restriction enzyme SfiI DUF572 PF04502.8 GAP88504.1 - 3.7 6.6 11.5 0.92 8.6 5.4 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF572) Glucosamine_iso PF01182.15 GAP88505.1 - 2.1e-58 197.3 0.0 2.5e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Hydrolase_6 PF13344.1 GAP88506.1 - 1.1e-27 95.9 0.0 1.8e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAP88506.1 - 4.5e-13 48.7 0.0 7.7e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 GAP88506.1 - 4.8e-13 50.0 0.0 8.9e-13 49.1 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 GAP88506.1 - 2.6e-06 27.7 0.0 0.0012 19.1 0.1 2.7 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAP88506.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase CorA PF01544.13 GAP88507.1 - 1.5e-07 30.7 1.6 1.8e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Poxvirus_B22R PF04395.7 GAP88508.1 - 0.08 12.4 3.6 0.14 11.6 2.5 1.5 1 0 0 1 1 1 0 Poxvirus B22R protein DHFR_1 PF00186.14 GAP88509.1 - 2.4e-22 79.2 0.0 3e-20 72.4 0.0 2.8 2 1 0 2 2 2 2 Dihydrofolate reductase Ubiq_cyt_C_chap PF03981.7 GAP88510.1 - 2.2e-38 131.2 0.6 3.6e-38 130.6 0.4 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone ketoacyl-synt PF00109.21 GAP88511.1 - 1.5e-58 198.2 4.0 1.5e-57 195.0 0.7 2.1 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 GAP88511.1 - 9.9e-34 115.7 2.9 2e-33 114.7 1.6 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 GAP88511.1 - 6.6e-06 25.2 0.1 1.9e-05 23.8 0.1 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAP88511.1 - 0.004 16.5 4.9 0.0077 15.6 0.3 3.1 2 2 1 3 3 3 1 Thiolase, C-terminal domain OPT PF03169.10 GAP88512.1 - 6.4e-180 599.6 53.9 7.3e-180 599.4 37.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1762 PF08574.5 GAP88514.1 - 1e-09 38.6 11.0 1e-09 38.6 7.6 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF1762) Lamp PF01299.12 GAP88515.1 - 2.3 7.2 4.6 4 6.4 3.2 1.3 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) His_Phos_1 PF00300.17 GAP88516.1 - 5.5e-25 88.3 0.0 7.5e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DEAD PF00270.24 GAP88518.1 - 1.4e-30 105.9 0.1 2.9e-30 104.9 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP88518.1 - 2.5e-17 62.4 0.0 6.2e-17 61.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAP88518.1 - 0.00061 19.6 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-MYND PF01753.13 GAP88519.1 - 3.9e-08 33.0 16.8 6.5e-08 32.3 11.7 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 GAP88519.1 - 0.0063 16.3 6.2 0.013 15.3 4.3 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 OrfB_Zn_ribbon PF07282.6 GAP88519.1 - 0.012 15.2 1.2 0.022 14.3 0.8 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain YL1 PF05764.8 GAP88520.1 - 2.5e-56 190.9 28.6 2.5e-56 190.9 19.8 2.2 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.6 GAP88520.1 - 3.3e-16 58.5 1.2 3.4e-15 55.3 0.4 2.3 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain GOLD_2 PF13897.1 GAP88520.1 - 0.084 13.0 1.3 0.29 11.3 0.9 1.9 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF2423 PF10338.4 GAP88521.1 - 8.9e-16 57.5 3.8 8.9e-16 57.5 2.7 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2423) DUF796 PF05638.7 GAP88521.1 - 0.029 14.3 0.9 0.04 13.9 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF796) PINIT PF14324.1 GAP88522.1 - 9.8e-36 122.9 0.1 2.2e-35 121.8 0.0 1.6 2 0 0 2 2 2 1 PINIT domain zf-MIZ PF02891.15 GAP88522.1 - 1.5e-20 72.4 6.3 2.6e-20 71.6 4.4 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 GAP88522.1 - 6e-06 25.6 1.4 1.4e-05 24.5 1.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 GAP88522.1 - 0.00025 20.4 0.2 0.00048 19.5 0.1 1.5 1 0 0 1 1 1 1 SAP domain zf-Sec23_Sec24 PF04810.10 GAP88522.1 - 0.064 12.8 5.2 0.48 10.0 3.2 2.6 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger TRAPP PF04051.11 GAP88523.1 - 3.6e-40 136.9 0.0 4.7e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ldh_1_N PF00056.18 GAP88524.1 - 5e-43 146.3 0.2 7e-43 145.8 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 GAP88524.1 - 1.8e-42 144.9 0.0 2.6e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 GAP88524.1 - 0.0023 16.6 0.0 0.0036 16.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ribosomal_L28e PF01778.12 GAP88525.1 - 1.5e-37 128.5 1.1 1.8e-37 128.3 0.7 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF2015 PF09435.5 GAP88526.1 - 5.4e-44 149.0 0.0 6e-44 148.9 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) FA_hydroxylase PF04116.8 GAP88527.1 - 2.8e-11 43.8 20.7 3.5e-11 43.5 12.4 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily FtsX PF02687.16 GAP88527.1 - 0.12 12.1 1.9 0.22 11.3 0.1 1.9 2 0 0 2 2 2 0 FtsX-like permease family DUF3328 PF11807.3 GAP88528.1 - 5.1e-53 179.9 0.0 1.7e-52 178.2 0.0 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) Tup_N PF08581.5 GAP88529.1 - 3e-24 84.9 6.5 3.5e-24 84.7 4.5 1.1 1 0 0 1 1 1 1 Tup N-terminal LXG PF04740.7 GAP88529.1 - 0.0095 15.7 1.0 0.011 15.4 0.7 1.0 1 0 0 1 1 1 1 LXG domain of WXG superfamily DUF4128 PF13554.1 GAP88529.1 - 0.069 12.8 0.1 0.098 12.3 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage related domain of unknown function Peptidase_M15_3 PF08291.6 GAP88529.1 - 0.076 12.8 0.0 0.16 11.7 0.0 1.5 1 1 0 1 1 1 0 Peptidase M15 Gal-3-0_sulfotr PF06990.6 GAP88529.1 - 0.11 11.0 0.3 0.13 10.8 0.2 1.1 1 0 0 1 1 1 0 Galactose-3-O-sulfotransferase COMP PF11598.3 GAP88529.1 - 0.34 11.0 0.5 0.34 11.0 0.3 2.6 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein Cutinase PF01083.17 GAP88532.1 - 1.3e-32 113.0 0.7 2.1e-32 112.2 0.5 1.3 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 GAP88532.1 - 0.0014 18.1 1.0 0.0017 17.7 0.1 1.5 2 0 0 2 2 2 1 PE-PPE domain Abhydrolase_2 PF02230.11 GAP88532.1 - 0.0048 16.3 0.0 0.011 15.1 0.0 1.5 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 GAP88532.1 - 0.0087 15.8 0.9 0.012 15.4 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 GAP88532.1 - 0.025 13.9 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.8 GAP88532.1 - 0.29 10.6 1.8 0.19 11.2 0.1 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold HET PF06985.6 GAP88534.1 - 3.2e-19 69.4 0.0 6.5e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) OGFr_N PF04664.8 GAP88535.1 - 1.4e-20 73.5 0.0 5.1e-12 45.5 0.0 2.0 2 0 0 2 2 2 2 Opioid growth factor receptor (OGFr) conserved region DUF1289 PF06945.8 GAP88535.1 - 0.07 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) adh_short PF00106.20 GAP88536.1 - 6e-28 97.8 0.6 8.3e-28 97.3 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP88536.1 - 3.3e-15 56.5 0.0 4.3e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP88536.1 - 6.4e-10 38.9 0.2 1e-09 38.3 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAP88536.1 - 1.1e-05 25.4 0.4 2.7e-05 24.2 0.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAP88536.1 - 8.5e-05 22.0 0.0 0.00042 19.8 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAP88536.1 - 0.0012 18.5 0.0 0.0039 16.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 GAP88536.1 - 0.0029 16.5 0.0 0.014 14.2 0.0 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain DUF1776 PF08643.5 GAP88536.1 - 0.0042 16.2 0.0 0.0054 15.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) UPF0261 PF06792.6 GAP88536.1 - 0.056 11.9 0.1 0.085 11.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) Ras PF00071.17 GAP88538.1 - 1.1e-38 132.1 0.0 1.3e-24 86.3 0.0 2.0 2 0 0 2 2 2 2 Ras family Miro PF08477.8 GAP88538.1 - 6.9e-12 45.9 0.0 1.2e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 GAP88538.1 - 0.0011 18.8 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 GAP88538.1 - 0.0022 17.2 0.0 0.0081 15.4 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAP88538.1 - 0.0063 15.9 0.0 0.18 11.2 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PRK PF00485.13 GAP88538.1 - 0.04 13.4 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Asp PF00026.18 GAP88539.1 - 6.1e-51 173.5 0.0 7.5e-51 173.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 GAP88539.1 - 0.0034 17.8 0.0 0.79 10.2 0.0 2.9 2 1 0 2 2 2 1 Aspartyl protease TAXi_N PF14543.1 GAP88539.1 - 0.0076 16.2 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 GAP88539.1 - 0.022 14.5 0.3 1 9.2 0.0 2.7 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease Sporozoite_P67 PF05642.6 GAP88540.1 - 6.3 4.5 7.1 6.6 4.4 4.9 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AMMECR1 PF01871.12 GAP88541.1 - 3.3e-47 159.7 0.0 2.5e-46 156.9 0.0 1.9 2 0 0 2 2 2 1 AMMECR1 DUF455 PF04305.9 GAP88542.1 - 4.2e-102 340.7 0.0 5.3e-102 340.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.21 GAP88542.1 - 5.6e-07 29.0 0.0 1.1e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 GAP88542.1 - 0.00067 19.3 0.0 0.0021 17.7 0.0 1.9 1 1 0 1 1 1 1 Rieske-like [2Fe-2S] domain Clc-like PF07062.7 GAP88543.1 - 0.5 9.5 3.3 0.28 10.4 0.5 1.7 1 1 1 2 2 2 0 Clc-like Piwi PF02171.12 GAP88545.1 - 1.3e-78 264.0 0.0 2.1e-78 263.3 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 GAP88545.1 - 1.6e-13 50.1 0.1 3.5e-13 49.0 0.1 1.6 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 GAP88545.1 - 6.9e-13 47.7 0.0 1.8e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Suf PF05843.9 GAP88546.1 - 2.8e-72 243.8 0.2 8.9e-71 238.8 0.0 2.8 2 1 0 2 2 2 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 GAP88546.1 - 0.017 15.7 5.7 0.65 10.7 0.0 5.5 4 2 3 7 7 7 0 Tetratricopeptide repeat Amidohydro_2 PF04909.9 GAP88547.1 - 8.3e-23 81.3 0.0 1.1e-22 80.9 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Abhydrolase_3 PF07859.8 GAP88548.1 - 1e-22 80.7 0.3 1.5e-22 80.2 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 GAP88548.1 - 1.5e-07 30.3 0.0 2.2e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 GAP88548.1 - 0.00025 20.7 0.7 0.00035 20.3 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 GAP88548.1 - 0.077 13.2 1.3 0.15 12.2 0.9 1.4 1 0 0 1 1 1 0 Thioesterase domain Lipoxygenase PF00305.14 GAP88549.1 - 5.7e-25 87.4 0.1 8.9e-24 83.4 0.0 2.0 1 1 0 1 1 1 1 Lipoxygenase ASF1_hist_chap PF04729.8 GAP88550.1 - 1.4e-65 219.6 0.0 1.8e-65 219.2 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone FMN_dh PF01070.13 GAP88551.1 - 1.8e-25 89.5 1.6 2.6e-25 89.0 1.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 GAP88551.1 - 2.7e-20 71.9 0.0 4.2e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FMN_dh PF01070.13 GAP88552.1 - 3.4e-59 200.4 1.5 3.9e-59 200.2 1.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 GAP88552.1 - 9.6e-06 24.7 0.9 2.6e-05 23.3 0.1 1.8 1 1 1 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.20 GAP88552.1 - 0.0023 16.8 0.7 0.0048 15.8 0.1 1.7 1 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 GAP88552.1 - 0.0048 16.0 0.5 0.0048 16.0 0.3 1.5 2 0 0 2 2 2 1 Nitronate monooxygenase ThiG PF05690.9 GAP88552.1 - 0.035 13.1 0.2 0.27 10.2 0.0 2.0 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DUF4066 PF13278.1 GAP88552.1 - 0.061 12.5 0.1 0.12 11.5 0.0 1.5 1 1 0 1 1 1 0 Putative amidotransferase DUF3129 PF11327.3 GAP88553.1 - 1.3e-57 194.5 10.0 1.8e-57 194.1 6.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) I-set PF07679.11 GAP88553.1 - 0.024 14.4 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ig_2 PF13895.1 GAP88553.1 - 0.048 13.7 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain Alginate_lyase PF05426.7 GAP88555.1 - 1.9e-20 73.3 0.6 4.5e-20 72.1 0.4 1.6 1 1 0 1 1 1 1 Alginate lyase DUF4310 PF14187.1 GAP88555.1 - 0.075 12.5 0.3 0.15 11.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4310) Glyco_hydro_28 PF00295.12 GAP88556.1 - 3.5e-11 42.6 1.2 6.8e-11 41.6 0.5 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 GAP88556.1 - 0.00083 19.1 16.2 0.13 12.0 11.2 3.1 1 1 0 1 1 1 1 Right handed beta helix region Fungal_trans PF04082.13 GAP88557.1 - 7.9e-11 41.3 3.4 1.2e-09 37.3 2.3 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP88557.1 - 8.4e-09 35.2 14.4 1.9e-08 34.0 10.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 GAP88558.1 - 1.3e-28 99.7 32.6 1.3e-28 99.7 22.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 GAP88558.1 - 0.3 11.1 7.2 0.29 11.2 0.3 3.9 2 1 1 4 4 4 0 Protein of unknown function (DUF1228) Glyco_hydro_88 PF07470.8 GAP88559.1 - 3e-18 65.9 0.5 4.1e-18 65.5 0.4 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF4550 PF15084.1 GAP88559.1 - 0.15 12.1 0.0 0.48 10.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4550) Alginate_lyase PF05426.7 GAP88560.1 - 9.4e-08 31.7 3.3 4.6e-07 29.4 2.2 1.8 1 1 0 1 1 1 1 Alginate lyase GMC_oxred_N PF00732.14 GAP88561.1 - 1.1e-27 96.9 0.0 1.5e-19 70.2 0.0 3.2 3 0 0 3 3 3 3 GMC oxidoreductase GMC_oxred_C PF05199.8 GAP88561.1 - 7.3e-27 94.4 0.1 1.3e-26 93.5 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAP88561.1 - 3.6e-06 26.1 0.2 0.00062 18.7 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAP88561.1 - 0.00019 21.3 0.8 0.0006 19.7 0.5 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAP88561.1 - 0.00023 21.1 0.1 0.0015 18.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAP88561.1 - 0.0053 15.6 0.6 0.01 14.7 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.11 GAP88561.1 - 0.0098 15.3 0.7 0.019 14.4 0.5 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 GAP88561.1 - 0.023 13.2 0.2 0.058 11.8 0.2 1.5 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.1 GAP88561.1 - 0.024 14.6 0.2 0.76 9.8 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAP88561.1 - 0.041 12.7 0.6 0.074 11.9 0.4 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A ThiF PF00899.16 GAP88561.1 - 0.064 13.0 0.2 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 ThiF family 3HCDH_N PF02737.13 GAP88561.1 - 0.068 12.8 0.1 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PTR2 PF00854.16 GAP88562.1 - 1.2e-36 126.3 15.2 1.6e-19 69.9 0.0 2.8 2 1 0 2 2 2 2 POT family MFS_1 PF07690.11 GAP88562.1 - 3.9e-07 29.1 30.3 0.00027 19.7 20.8 4.1 2 1 0 2 2 2 1 Major Facilitator Superfamily BAF1_ABF1 PF04684.8 GAP88563.1 - 0.017 13.9 4.3 0.023 13.5 3.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PAT1 PF09770.4 GAP88563.1 - 2.6 6.1 7.7 2.9 6.0 5.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SelP_N PF04592.9 GAP88563.1 - 3.2 7.0 6.5 4.3 6.6 4.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TFIIA PF03153.8 GAP88563.1 - 5 6.9 6.8 5.4 6.8 4.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MIP-T3 PF10243.4 GAP88563.1 - 7.7 4.8 10.1 9.7 4.5 7.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 TPP_enzyme_N PF02776.13 GAP88564.1 - 1.7e-36 125.3 0.3 2.8e-36 124.5 0.2 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 GAP88564.1 - 4.9e-18 65.2 0.0 1.8e-17 63.3 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 GAP88564.1 - 3.5e-17 62.3 0.2 3.3e-16 59.2 0.0 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain RasGAP PF00616.14 GAP88565.1 - 6.3e-51 172.8 0.7 2.2e-50 171.0 0.0 2.3 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 GAP88565.1 - 2.7e-31 108.1 4.8 2.7e-31 108.1 3.4 2.0 2 0 0 2 2 2 1 RasGAP C-terminus MeMO_Hyd_G PF02964.11 GAP88565.1 - 0.046 13.6 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Methane monooxygenase, hydrolase gamma chain Ank_2 PF12796.2 GAP88566.1 - 1.1e-84 278.8 28.7 9.7e-17 61.0 0.1 11.5 2 1 9 11 11 11 10 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAP88566.1 - 4e-78 256.5 41.2 1.4e-12 47.7 0.1 14.2 3 2 10 13 13 13 13 Ankyrin repeats (many copies) Ank PF00023.25 GAP88566.1 - 5.7e-72 234.1 71.9 3.9e-09 35.8 0.0 18.6 14 8 0 14 14 14 14 Ankyrin repeat Ank_3 PF13606.1 GAP88566.1 - 3.3e-67 215.6 20.6 3.7e-05 23.5 0.0 16.5 15 0 0 15 15 15 13 Ankyrin repeat Ank_5 PF13857.1 GAP88566.1 - 1.1e-64 212.9 29.3 1.7e-11 43.9 0.1 11.3 3 2 8 12 12 12 12 Ankyrin repeats (many copies) NACHT PF05729.7 GAP88566.1 - 1e-08 35.0 0.0 1.9e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 GAP88566.1 - 4e-05 23.6 0.3 0.00026 21.0 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain RVP PF00077.15 GAP88566.1 - 6.6e-05 22.7 12.3 8.5 6.3 0.1 8.2 3 2 4 7 7 7 0 Retroviral aspartyl protease DUF4147 PF13660.1 GAP88566.1 - 0.00019 20.6 15.6 0.43 9.6 0.2 7.6 5 2 5 10 10 10 3 Domain of unknown function (DUF4147) EKR PF10371.4 GAP88566.1 - 0.00037 20.0 0.0 21 4.7 0.0 6.0 7 0 0 7 7 7 0 Domain of unknown function gag-asp_proteas PF13975.1 GAP88566.1 - 0.0017 18.1 1.3 15 5.5 0.0 5.1 5 1 1 6 6 5 0 gag-polyprotein putative aspartyl protease AAA_22 PF13401.1 GAP88566.1 - 0.0024 18.0 0.0 0.0089 16.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 GAP88566.1 - 0.0069 16.5 0.0 0.022 14.9 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.1 GAP88566.1 - 0.014 15.2 0.0 0.036 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 GAP88566.1 - 0.045 14.0 0.0 0.19 12.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_17 PF13207.1 GAP88566.1 - 0.097 13.5 0.0 0.4 11.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 GAP88566.1 - 0.12 12.1 0.0 27 4.4 0.0 4.3 3 1 1 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B CholecysA-Rec_N PF09193.5 GAP88566.1 - 0.16 11.8 5.6 29 4.6 0.1 4.6 4 0 0 4 4 4 0 Cholecystokinin A receptor, N-terminal Glyco_hydro_cc PF11790.3 GAP88567.1 - 1.6e-49 168.5 0.0 2e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core GST_N_2 PF13409.1 GAP88568.1 - 0.0007 19.5 0.0 0.0017 18.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAP88568.1 - 0.00074 19.6 0.0 0.011 15.9 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAP88568.1 - 0.024 14.5 3.1 0.037 13.8 0.6 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain COesterase PF00135.23 GAP88570.1 - 2e-87 294.1 0.2 1.8e-78 264.6 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 GAP88570.1 - 0.0032 17.0 0.0 0.0055 16.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold EKR PF10371.4 GAP88570.1 - 0.14 11.7 0.0 0.37 10.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function MFS_1 PF07690.11 GAP88571.1 - 2.4e-24 85.7 36.1 1.4e-23 83.2 18.5 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP88571.1 - 9.9e-10 37.5 1.6 9.9e-10 37.5 1.1 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 GAP88571.1 - 5.7e-06 24.9 3.0 5.7e-06 24.9 2.1 2.7 1 1 1 2 2 2 2 MFS/sugar transport protein OATP PF03137.15 GAP88571.1 - 0.0057 14.7 0.1 0.016 13.2 0.1 1.9 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Acetyltransf_1 PF00583.19 GAP88574.1 - 3e-11 43.1 0.0 5.8e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 GAP88574.1 - 3.4e-11 43.4 0.0 6.1e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAP88574.1 - 1e-05 25.5 0.0 3.1e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAP88574.1 - 0.00013 21.8 0.0 0.00029 20.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAP88574.1 - 0.022 14.5 0.1 0.071 12.8 0.0 1.9 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_7 PF13508.1 GAP88574.1 - 0.1 12.7 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Folate_carrier PF01770.13 GAP88574.1 - 0.4 9.1 0.1 0.61 8.5 0.1 1.2 1 0 0 1 1 1 0 Reduced folate carrier DASH_Spc34 PF08657.5 GAP88577.1 - 2.4e-21 76.6 0.9 2.6e-21 76.4 0.6 1.0 1 0 0 1 1 1 1 DASH complex subunit Spc34 BTV_NS2 PF04514.7 GAP88577.1 - 0.018 13.9 1.8 0.023 13.5 1.2 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DASH_Spc19 PF08287.6 GAP88577.1 - 0.12 12.0 2.4 0.14 11.7 1.6 1.2 1 0 0 1 1 1 0 Spc19 V_ATPase_I PF01496.14 GAP88577.1 - 0.18 9.6 1.0 0.2 9.4 0.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family V-SNARE PF05008.10 GAP88577.1 - 0.2 11.8 2.7 2.1 8.5 0.4 2.1 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Uds1 PF15456.1 GAP88577.1 - 0.68 9.9 5.4 1.1 9.2 3.8 1.4 1 1 0 1 1 1 0 Up-regulated During Septation NOA36 PF06524.7 GAP88577.1 - 3.6 6.7 6.6 4.1 6.5 4.6 1.1 1 0 0 1 1 1 0 NOA36 protein DASH_Spc34 PF08657.5 GAP88578.1 - 2e-25 89.9 0.2 3.3e-25 89.2 0.1 1.4 1 1 0 1 1 1 1 DASH complex subunit Spc34 PSCyt3 PF07627.6 GAP88578.1 - 0.0088 15.8 0.1 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1588) Mito_fiss_reg PF05308.6 GAP88578.1 - 0.1 11.9 1.3 0.11 11.8 0.9 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator NeA_P2 PF12312.3 GAP88578.1 - 4.3 6.4 6.2 1 8.5 1.7 1.7 1 1 1 2 2 2 0 Nepovirus subgroup A polyprotein TFIID_20kDa PF03847.8 GAP88580.1 - 9.4e-21 73.8 0.0 1.5e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 GAP88580.1 - 0.007 16.3 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone BAF1_ABF1 PF04684.8 GAP88580.1 - 0.57 8.9 9.9 1 8.1 6.9 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Rpn3_C PF08375.6 GAP88581.1 - 7.1e-25 87.1 0.8 2.1e-24 85.6 0.6 1.9 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 GAP88581.1 - 2.2e-20 72.9 0.3 8.2e-20 71.0 0.0 2.1 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.12 GAP88581.1 - 0.01 15.7 0.1 0.041 13.7 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat PCI_Csn8 PF10075.4 GAP88581.1 - 0.068 12.9 0.1 0.33 10.7 0.1 2.1 1 1 0 1 1 1 0 COP9 signalosome, subunit CSN8 MOZ_SAS PF01853.13 GAP88582.1 - 3.1e-46 157.0 0.0 2.9e-30 104.9 0.0 2.8 3 0 0 3 3 3 2 MOZ/SAS family ATP-synt_C PF00137.16 GAP88583.1 - 2.1e-16 59.5 10.5 4.9e-16 58.3 7.3 1.7 1 0 0 1 1 1 1 ATP synthase subunit C MFS_3 PF05977.8 GAP88583.1 - 0.93 7.5 8.2 1.7 6.6 3.2 2.0 1 1 1 2 2 2 0 Transmembrane secretion effector zf-C2H2_4 PF13894.1 GAP88586.1 - 0.00014 21.9 20.5 0.028 14.7 0.8 4.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAP88586.1 - 0.00063 19.9 0.3 0.00063 19.9 0.2 3.9 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2 PF00096.21 GAP88586.1 - 0.0012 19.0 23.7 0.018 15.3 0.7 4.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-CHCC PF10276.4 GAP88586.1 - 0.088 12.6 3.9 2.8 7.8 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2_6 PF13912.1 GAP88586.1 - 1.1 9.2 6.4 9.8 6.2 0.6 3.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 GAP88586.1 - 6.4 6.6 8.3 9.6 6.0 0.4 3.4 3 0 0 3 3 3 0 BED zinc finger DSPc PF00782.15 GAP88587.1 - 1.8e-15 56.6 0.3 6.8e-06 25.6 0.2 3.1 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 GAP88587.1 - 0.15 10.9 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Vfa1 PF08432.5 GAP88589.1 - 5e-57 192.8 28.7 1.7e-56 191.1 19.9 1.7 1 1 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Atrophin-1 PF03154.10 GAP88589.1 - 0.0069 14.6 20.0 0.0096 14.1 13.9 1.3 1 0 0 1 1 1 1 Atrophin-1 family CDC45 PF02724.9 GAP88589.1 - 0.038 12.0 21.9 0.045 11.7 15.2 1.0 1 0 0 1 1 1 0 CDC45-like protein SET PF00856.23 GAP88589.1 - 0.068 13.4 2.9 0.089 13.0 2.0 1.3 1 0 0 1 1 1 0 SET domain Ycf1 PF05758.7 GAP88589.1 - 0.16 9.6 19.4 0.19 9.4 13.4 1.0 1 0 0 1 1 1 0 Ycf1 Herpes_MCP PF03122.9 GAP88589.1 - 0.23 8.7 1.8 0.32 8.2 1.2 1.1 1 0 0 1 1 1 0 Herpes virus major capsid protein MIP-T3 PF10243.4 GAP88589.1 - 0.37 9.2 44.8 0.44 8.9 31.0 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2201_N PF13203.1 GAP88589.1 - 0.79 8.8 13.5 0.99 8.5 9.4 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Astro_capsid PF03115.9 GAP88589.1 - 0.9 7.7 6.0 0.97 7.6 4.2 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor FLO_LFY PF01698.11 GAP88589.1 - 1.2 7.8 15.0 1.6 7.4 10.4 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF106 PF01956.11 GAP88589.1 - 3 7.3 6.8 4.7 6.7 4.7 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF106 GCD14 PF08704.5 GAP88589.1 - 3.8 6.9 8.2 5.4 6.4 5.7 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Pox_Ag35 PF03286.9 GAP88589.1 - 5.3 6.5 28.0 8.2 5.8 19.4 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF913 PF06025.7 GAP88589.1 - 9.5 4.8 6.7 13 4.4 4.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Rtt106 PF08512.7 GAP88590.1 - 9.8e-25 86.3 0.0 3.7e-24 84.5 0.0 1.9 2 0 0 2 2 2 1 Histone chaperone Rttp106-like TFIIA PF03153.8 GAP88590.1 - 0.0015 18.5 3.3 0.0015 18.5 2.3 1.8 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Asp PF00026.18 GAP88591.1 - 9.3e-28 97.3 0.0 1.5e-27 96.7 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAP88591.1 - 7.8e-05 22.6 0.5 0.00053 19.9 0.1 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal p450 PF00067.17 GAP88592.1 - 2.5e-38 131.8 0.0 3.1e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 XPG_I PF00867.13 GAP88593.1 - 1.5e-09 37.7 0.1 3.1e-09 36.7 0.1 1.6 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 GAP88593.1 - 0.00036 20.7 0.0 0.00049 20.3 0.0 1.2 1 0 0 1 1 1 1 XPG N-terminal domain NACHT PF05729.7 GAP88593.1 - 0.091 12.4 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 NACHT domain VEFS-Box PF09733.4 GAP88596.1 - 3.6e-06 26.6 0.1 9.3e-06 25.3 0.1 1.7 1 0 0 1 1 1 1 VEFS-Box of polycomb protein PHD PF00628.24 GAP88596.1 - 5.9e-05 22.6 7.2 5.9e-05 22.6 5.0 2.1 2 0 0 2 2 2 1 PHD-finger zf-tcix PF14952.1 GAP88596.1 - 0.88 8.9 6.1 0.16 11.3 0.4 2.3 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding DNA_ligase_ZBD PF03119.11 GAP88596.1 - 1.1 8.9 5.4 4.3 7.1 3.7 2.0 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain Sugar_tr PF00083.19 GAP88597.1 - 5.1e-68 229.6 23.4 6e-68 229.4 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP88597.1 - 1.3e-12 47.0 24.8 2.1e-12 46.4 17.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 GAP88597.1 - 0.0021 16.5 2.9 0.0021 16.5 2.0 2.9 2 1 1 3 3 3 2 MFS/sugar transport protein OAD_gamma PF04277.8 GAP88597.1 - 0.17 12.2 0.6 0.42 11.0 0.4 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF3671 PF12420.3 GAP88597.1 - 0.27 11.2 1.1 5.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF2786 PF10979.3 GAP88597.1 - 3.8 7.3 5.6 0.56 9.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) DUF382 PF04037.8 GAP88598.1 - 7.8e-62 206.8 1.3 7.8e-62 206.8 0.9 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.11 GAP88598.1 - 3.6e-20 71.0 5.3 9e-20 69.8 3.6 1.7 1 0 0 1 1 1 1 PSP TPT PF03151.11 GAP88599.1 - 4.5e-39 133.5 0.5 4.5e-39 133.5 0.4 1.8 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 GAP88599.1 - 3e-05 24.0 26.0 0.0033 17.4 7.2 3.0 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 GAP88599.1 - 0.00026 20.0 14.6 0.0019 17.2 10.1 2.1 1 1 0 1 1 1 1 UAA transporter family M-factor PF03855.8 GAP88599.1 - 0.005 16.7 0.4 0.012 15.5 0.3 1.7 1 0 0 1 1 1 1 M-factor DUF914 PF06027.7 GAP88599.1 - 0.0098 14.7 5.0 0.031 13.1 0.1 2.9 2 1 1 3 3 3 1 Eukaryotic protein of unknown function (DUF914) ATP-synt_ab PF00006.20 GAP88600.1 - 1.9e-58 197.4 0.0 3.2e-58 196.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 GAP88600.1 - 6.7e-25 87.7 0.3 1.2e-24 86.9 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 GAP88600.1 - 1.2e-23 83.1 0.4 5.9e-23 80.8 0.1 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 GAP88600.1 - 0.0038 16.6 0.2 0.014 14.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 GAP88600.1 - 0.0093 16.1 0.0 0.38 10.9 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 GAP88600.1 - 0.0096 15.6 0.1 1.1 8.9 0.0 2.9 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B KaiC PF06745.8 GAP88600.1 - 0.013 14.5 0.1 0.022 13.8 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.1 GAP88600.1 - 0.014 15.5 0.0 0.088 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 GAP88600.1 - 0.014 15.0 0.0 0.032 13.9 0.0 1.5 2 0 0 2 2 2 0 Archaeal ATPase DUF258 PF03193.11 GAP88600.1 - 0.017 14.3 0.1 0.03 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 GAP88600.1 - 0.028 14.0 0.1 0.073 12.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 GAP88600.1 - 0.073 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF463 PF04317.7 GAP88600.1 - 0.11 11.0 0.0 0.28 9.6 0.0 1.6 2 0 0 2 2 2 0 YcjX-like family, DUF463 AAA_16 PF13191.1 GAP88600.1 - 0.11 12.5 0.2 0.33 10.9 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.17 GAP88600.1 - 0.15 10.9 0.3 0.65 8.8 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain Cu-oxidase_3 PF07732.10 GAP88601.1 - 4.8e-43 145.6 8.7 1.3e-41 141.0 1.0 3.9 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 GAP88601.1 - 3.3e-42 144.0 4.6 1.5e-37 128.9 0.3 2.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 GAP88601.1 - 5.7e-40 136.0 6.0 3.6e-36 123.7 0.1 3.0 3 1 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.1 GAP88601.1 - 0.0016 18.2 0.0 9 6.2 0.0 3.6 2 1 0 2 2 2 2 Cupredoxin-like domain FTR1 PF03239.9 GAP88602.1 - 6.5e-79 265.0 12.7 8e-79 264.7 8.8 1.1 1 0 0 1 1 1 1 Iron permease FTR1 family DUF4231 PF14015.1 GAP88602.1 - 0.026 14.4 2.4 0.23 11.4 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF1043 PF06295.7 GAP88602.1 - 0.071 12.7 0.6 1.4 8.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) XK-related PF09815.4 GAP88602.1 - 2 7.3 7.3 0.38 9.6 0.1 2.6 2 1 1 3 3 3 0 XK-related protein Snf7 PF03357.16 GAP88604.1 - 7.8e-19 67.6 1.1 7.8e-19 67.6 0.7 1.9 2 0 0 2 2 2 1 Snf7 TPR_MLP1_2 PF07926.7 GAP88604.1 - 0.03 14.0 0.0 0.061 13.0 0.0 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Exotox-A_cataly PF09009.5 GAP88604.1 - 0.11 11.3 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Exotoxin A catalytic DUF4404 PF14357.1 GAP88604.1 - 1.8 9.0 5.7 17 5.9 0.3 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) CS PF04969.11 GAP88605.1 - 1.1e-09 38.7 0.1 2e-09 37.8 0.1 1.5 1 0 0 1 1 1 1 CS domain Rep_1 PF01446.12 GAP88605.1 - 0.064 12.5 1.0 0.18 11.0 0.7 1.6 1 1 0 1 1 1 0 Replication protein DUF4202 PF13875.1 GAP88605.1 - 0.085 12.4 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) RMF PF04957.7 GAP88606.1 - 0.44 10.2 0.0 0.44 10.2 0.0 2.2 2 1 0 2 2 2 0 Ribosome modulation factor Vasculin PF15337.1 GAP88607.1 - 4.9 7.7 7.1 1.6 9.2 2.0 2.2 2 0 0 2 2 2 0 Vascular protein family Vasculin-like 1 PIG-H PF10181.4 GAP88609.1 - 7.4e-20 70.3 0.0 1.1e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component PseudoU_synth_1 PF01416.15 GAP88610.1 - 2.9e-30 104.7 0.0 8.4e-22 77.5 0.0 2.9 2 1 0 2 2 2 2 tRNA pseudouridine synthase Ras PF00071.17 GAP88611.1 - 2.3e-20 72.5 0.0 3.6e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAP88611.1 - 5.7e-10 39.7 0.0 8.2e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAP88611.1 - 0.0004 19.6 0.1 0.66 9.1 0.1 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_24 PF13479.1 GAP88611.1 - 0.00072 19.2 0.1 0.0091 15.5 0.0 2.4 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.22 GAP88611.1 - 0.0029 17.9 0.0 0.0038 17.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter NACHT PF05729.7 GAP88611.1 - 0.007 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 GAP88611.1 - 0.018 15.0 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 GAP88611.1 - 0.063 12.4 0.5 0.13 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 GAP88611.1 - 0.068 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 GAP88611.1 - 0.07 12.6 0.1 0.16 11.4 0.1 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 GAP88611.1 - 0.095 12.2 0.1 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 GAP88611.1 - 0.099 12.7 0.1 0.35 11.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.15 GAP88611.1 - 0.11 11.1 0.1 0.16 10.6 0.1 1.2 1 0 0 1 1 1 0 G-protein alpha subunit RNA_pol_Rpb4 PF03874.11 GAP88612.1 - 1.6e-16 60.3 0.0 1.9e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Myb_Cef PF11831.3 GAP88614.1 - 0.066 12.4 0.1 0.15 11.2 0.0 1.5 2 0 0 2 2 2 0 pre-mRNA splicing factor component ORC6 PF05460.8 GAP88615.1 - 1.2e-34 120.0 5.7 2.6e-34 118.8 3.9 1.6 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) EF-hand_6 PF13405.1 GAP88616.1 - 7.6e-08 31.6 0.0 0.0088 15.8 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 GAP88616.1 - 2.2e-06 27.6 4.7 0.00032 20.7 0.3 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 GAP88616.1 - 9.8e-05 21.3 0.0 0.0039 16.3 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 GAP88616.1 - 0.0015 17.7 0.1 0.014 14.7 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 GAP88616.1 - 0.0031 17.1 0.1 0.036 13.6 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair DUF959 PF06121.9 GAP88617.1 - 3.1e-05 23.7 0.1 5.9e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF959) Met_10 PF02475.11 GAP88617.1 - 0.0002 21.0 0.0 0.0017 17.9 0.0 2.2 2 0 0 2 2 2 1 Met-10+ like-protein DUF3439 PF11921.3 GAP88617.1 - 0.03 14.0 5.2 0.05 13.3 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 GAP88617.1 - 0.034 13.9 8.0 0.07 12.9 5.6 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein UspB PF10625.4 GAP88617.1 - 0.22 11.3 0.1 0.44 10.3 0.0 1.4 1 0 0 1 1 1 0 Universal stress protein B (UspB) SSP160 PF06933.6 GAP88617.1 - 0.52 8.2 9.8 0.69 7.8 6.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.7 GAP88617.1 - 1.9 6.1 4.8 2.5 5.7 3.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Methyltransf_26 PF13659.1 GAP88617.1 - 5.4 7.0 10.0 0.89 9.6 3.4 2.5 2 2 0 2 2 2 0 Methyltransferase domain Ribosomal_S13 PF00416.17 GAP88619.1 - 2.3e-39 134.1 0.4 2.8e-39 133.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 GAP88619.1 - 0.0026 16.3 0.0 0.0028 16.2 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH PF00633.18 GAP88619.1 - 0.12 12.0 0.1 0.5 10.1 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF2638 PF10937.3 GAP88620.1 - 2.2e-33 115.6 1.1 2.8e-33 115.2 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) PNK3P PF08645.6 GAP88621.1 - 6.9e-53 178.3 0.0 1.1e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 GAP88621.1 - 6.5e-33 113.6 0.0 2.4e-32 111.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 GAP88621.1 - 0.00079 18.7 0.2 0.95 8.6 0.0 2.3 1 1 1 2 2 2 2 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 GAP88621.1 - 0.0017 17.4 0.0 0.017 14.2 0.0 2.3 2 1 1 3 3 3 1 Zeta toxin AAA_17 PF13207.1 GAP88621.1 - 0.0071 17.1 0.7 0.089 13.6 0.5 2.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 GAP88621.1 - 0.012 15.0 0.0 0.036 13.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 GAP88621.1 - 0.017 15.2 0.0 0.045 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 GAP88621.1 - 0.1 12.5 0.0 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 GAP88621.1 - 0.12 11.2 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein HAD_2 PF13419.1 GAP88621.1 - 0.14 12.4 0.1 23 5.1 0.0 2.6 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase AAA_23 PF13476.1 GAP88621.1 - 0.15 12.3 0.1 0.36 11.1 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 GAP88621.1 - 0.21 11.8 0.2 2.1 8.6 0.1 2.2 1 1 1 2 2 2 0 AAA domain Rad17 PF03215.10 GAP88621.1 - 0.25 9.9 0.0 0.37 9.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein XPA_C PF05181.7 GAP88622.1 - 2.1e-28 97.6 2.2 4.7e-28 96.5 1.5 1.6 1 0 0 1 1 1 1 XPA protein C-terminus ArfGap PF01412.13 GAP88622.1 - 0.02 14.6 0.3 0.052 13.3 0.2 1.7 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Etmic-2 PF06670.6 GAP88622.1 - 0.67 8.6 3.2 0.96 8.0 2.3 1.1 1 0 0 1 1 1 0 Microneme protein Etmic-2 FYVE PF01363.16 GAP88622.1 - 1.1 9.2 5.3 13 5.8 3.7 2.2 1 1 0 1 1 1 0 FYVE zinc finger zf-C2H2_3 PF13878.1 GAP88622.1 - 2.2 7.9 6.8 1.4 8.5 0.3 3.0 3 0 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO TF_Zn_Ribbon PF08271.7 GAP88622.1 - 7.8 5.9 9.0 14 5.1 0.5 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding YhfH PF14149.1 GAP88622.1 - 9 6.1 8.6 0.66 9.8 0.3 2.7 3 0 0 3 3 3 0 YhfH-like protein XPA_N PF01286.13 GAP88622.1 - 9.4 6.0 14.4 0.052 13.2 3.2 2.2 3 0 0 3 3 3 0 XPA protein N-terminal Pkinase PF00069.20 GAP88623.1 - 1.5e-05 24.3 0.3 4.8e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Choline_kinase PF01633.15 GAP88623.1 - 0.0011 18.5 0.0 0.0028 17.2 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 GAP88623.1 - 0.035 13.8 0.0 0.035 13.8 0.0 3.0 3 1 1 4 4 4 0 Phosphotransferase enzyme family Pho88 PF10032.4 GAP88624.1 - 3.7e-79 264.4 0.0 4.2e-79 264.2 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) CAP_N PF01213.14 GAP88625.1 - 0.44 9.7 0.9 0.79 8.9 0.6 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal p450 PF00067.17 GAP88626.1 - 5.6e-69 232.8 0.0 8.2e-69 232.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 GAP88626.1 - 1.4e-32 112.9 0.0 2.5e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 GAP88626.1 - 4.6e-24 85.0 0.1 1.2e-23 83.6 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 GAP88626.1 - 8e-10 39.2 0.0 2e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 GAP88626.1 - 0.09 12.7 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 Flavodoxin domain DUF2017 PF09438.5 GAP88626.1 - 0.14 11.6 1.0 8.3 5.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2017) Abhydrolase_6 PF12697.2 GAP88627.1 - 8.8e-22 78.1 12.8 8.8e-22 78.1 8.9 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP88627.1 - 9.7e-06 25.3 1.3 6.7e-05 22.6 0.4 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP88627.1 - 6.9e-05 22.5 0.0 0.00038 20.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 GAP88627.1 - 0.00053 19.4 0.0 0.0012 18.3 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.9 GAP88627.1 - 0.0015 17.1 0.0 0.0022 16.4 0.0 1.3 1 0 0 1 1 1 1 Ndr family EthD PF07110.6 GAP88627.1 - 0.018 15.9 1.9 0.21 12.5 0.1 3.3 4 0 0 4 4 4 0 EthD domain DUF1479 PF07350.7 GAP88629.1 - 2.9e-151 503.6 0.0 3.9e-151 503.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) ABC2_membrane_3 PF12698.2 GAP88629.1 - 2.7 6.9 6.4 4.8 6.1 4.4 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Cuticle_2 PF08184.6 GAP88630.1 - 0.02 14.6 0.1 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Cuticle protein 7 isoform family PsbI PF02532.9 GAP88631.1 - 0.41 10.3 1.6 0.71 9.5 0.1 2.0 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Peptidase_M35 PF02102.10 GAP88632.1 - 1.6e-77 260.6 14.6 1.9e-77 260.3 10.1 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 GAP88632.1 - 2.9e-07 31.0 0.7 4.7e-07 30.4 0.3 1.5 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase p450 PF00067.17 GAP88633.1 - 1.2e-06 27.3 0.0 1.3e-06 27.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 GAP88634.1 - 4.2e-57 193.6 0.0 5.1e-57 193.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BTV_NS2 PF04514.7 GAP88634.1 - 0.26 10.1 4.4 0.38 9.5 3.1 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Ycf1 PF05758.7 GAP88634.1 - 0.29 8.8 2.2 0.26 8.9 1.0 1.3 2 0 0 2 2 2 0 Ycf1 DDRGK PF09756.4 GAP88634.1 - 0.34 10.3 15.0 0.51 9.7 10.4 1.2 1 0 0 1 1 1 0 DDRGK domain Pap_E4 PF02711.9 GAP88634.1 - 0.48 11.2 2.8 18 6.2 0.0 2.3 2 0 0 2 2 2 0 E4 protein FAM176 PF14851.1 GAP88634.1 - 0.52 9.9 3.6 0.8 9.3 2.5 1.3 1 0 0 1 1 1 0 FAM176 family Vfa1 PF08432.5 GAP88634.1 - 0.72 9.8 6.7 1.1 9.3 4.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Pox_Ag35 PF03286.9 GAP88634.1 - 0.74 9.3 7.0 1.1 8.7 4.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CENP-B_dimeris PF09026.5 GAP88634.1 - 0.75 10.0 5.8 1.5 9.1 4.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 GAP88634.1 - 0.85 9.9 8.1 2 8.7 5.6 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Paf1 PF03985.8 GAP88634.1 - 0.95 8.1 12.2 1.6 7.3 8.4 1.3 1 0 0 1 1 1 0 Paf1 TRAP_alpha PF03896.11 GAP88634.1 - 2.2 7.1 5.2 5 6.0 3.3 1.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Adeno_terminal PF02459.10 GAP88634.1 - 5.8 4.9 8.8 8.4 4.4 6.1 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein CDC45 PF02724.9 GAP88634.1 - 8.4 4.2 7.1 11 3.9 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein CorA PF01544.13 GAP88635.1 - 8.7e-07 28.2 0.2 4.7e-06 25.8 0.2 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3072 PF11272.3 GAP88635.1 - 0.029 14.0 0.9 0.077 12.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3072) Rotavirus_VP1 PF12289.3 GAP88635.1 - 0.05 13.2 0.1 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 Rotavirus VP1 structural protein EphA2_TM PF14575.1 GAP88636.1 - 0.0035 17.7 0.1 0.008 16.5 0.1 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain IncA PF04156.9 GAP88636.1 - 0.013 15.1 0.4 0.023 14.2 0.2 1.3 1 0 0 1 1 1 0 IncA protein Amnionless PF14828.1 GAP88636.1 - 0.025 13.1 0.0 0.037 12.5 0.0 1.2 1 0 0 1 1 1 0 Amnionless DAP10 PF07213.6 GAP88636.1 - 0.026 14.2 0.6 0.052 13.2 0.4 1.4 1 0 0 1 1 1 0 DAP10 membrane protein Syndecan PF01034.15 GAP88636.1 - 0.12 12.0 0.3 0.27 10.8 0.2 1.5 1 0 0 1 1 1 0 Syndecan domain Rifin_STEVOR PF02009.11 GAP88636.1 - 0.15 11.7 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Rifin/stevor family Mycobact_memb PF05423.8 GAP88636.1 - 0.15 11.7 1.7 0.16 11.6 0.1 1.7 2 0 0 2 2 2 0 Mycobacterium membrane protein Adeno_E3_CR2 PF02439.10 GAP88636.1 - 3.7 7.1 7.5 0.56 9.8 2.4 1.7 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Fungal_trans PF04082.13 GAP88637.1 - 4.6e-25 87.9 0.0 2.8e-24 85.4 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP88637.1 - 4.4e-08 32.8 8.4 7.2e-08 32.2 5.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-PHD-like PF15446.1 GAP88637.1 - 0.021 14.1 1.9 0.047 12.9 1.3 1.5 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain GPCR_chapero_1 PF11904.3 GAP88637.1 - 0.056 12.5 3.0 0.45 9.6 0.0 2.4 2 0 0 2 2 2 0 GPCR-chaperone Peptidase_M41 PF01434.13 GAP88638.1 - 1.3e-65 220.8 1.1 2.1e-65 220.1 0.7 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 GAP88638.1 - 8.8e-43 145.6 0.0 2.1e-42 144.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAP88638.1 - 1.8e-06 28.1 0.1 0.0075 16.4 0.1 3.8 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 GAP88638.1 - 9.2e-06 25.4 0.0 2.7e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 GAP88638.1 - 1.1e-05 26.2 0.0 3.3e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 GAP88638.1 - 3e-05 22.9 0.0 5.6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 GAP88638.1 - 4.1e-05 23.6 0.9 0.00066 19.7 0.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 GAP88638.1 - 0.00033 19.7 0.0 0.00078 18.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 GAP88638.1 - 0.0011 18.4 0.5 0.0062 15.9 0.1 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.1 GAP88638.1 - 0.0018 18.0 0.1 0.007 16.0 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 GAP88638.1 - 0.002 17.5 1.2 0.099 12.0 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 GAP88638.1 - 0.0027 17.5 0.0 0.0096 15.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 GAP88638.1 - 0.0043 16.9 0.0 0.013 15.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 GAP88638.1 - 0.0064 15.6 0.0 0.016 14.2 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 GAP88638.1 - 0.011 15.5 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 GAP88638.1 - 0.014 15.3 0.0 0.035 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 GAP88638.1 - 0.017 14.2 0.3 0.039 13.0 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 GAP88638.1 - 0.026 14.8 0.0 0.076 13.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain KaiC PF06745.8 GAP88638.1 - 0.031 13.4 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 KaiC Peptidase_M50B PF13398.1 GAP88638.1 - 0.23 10.8 0.1 0.23 10.8 0.0 1.8 2 0 0 2 2 2 0 Peptidase M50B-like GDPD PF03009.12 GAP88639.1 - 6.9e-69 232.1 0.0 1.6e-68 230.9 0.0 1.7 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 GAP88639.1 - 3.2e-31 107.4 0.3 4.6e-13 49.3 0.0 4.7 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) SPX PF03105.14 GAP88639.1 - 9.8e-28 97.7 4.8 1.1e-15 58.2 1.0 3.4 1 1 1 2 2 2 2 SPX domain Ank_4 PF13637.1 GAP88639.1 - 1.7e-26 92.0 3.5 2.8e-10 40.4 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.25 GAP88639.1 - 6.8e-24 82.4 7.1 1.1e-05 24.9 0.0 7.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 GAP88639.1 - 2.5e-20 72.0 2.4 1.3e-07 31.6 0.0 6.1 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP88639.1 - 5.6e-12 44.6 6.4 0.0029 17.7 0.0 7.3 7 0 0 7 7 7 3 Ankyrin repeat SRA1 PF07304.6 GAP88639.1 - 0.024 14.3 3.2 0.24 11.1 0.0 2.9 3 0 0 3 3 3 0 Steroid receptor RNA activator (SRA1) PPR_1 PF12854.2 GAP88640.1 - 0.0042 16.5 0.0 0.011 15.1 0.0 1.8 1 0 0 1 1 1 1 PPR repeat PPR_2 PF13041.1 GAP88640.1 - 0.044 13.7 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 PPR repeat family DUF866 PF05907.8 GAP88641.1 - 2.9e-48 163.4 0.2 3.2e-48 163.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) PHD PF00628.24 GAP88641.1 - 0.017 14.8 0.4 0.044 13.4 0.3 1.7 1 0 0 1 1 1 0 PHD-finger Zn_Tnp_IS1595 PF12760.2 GAP88641.1 - 0.1 12.3 3.8 0.27 11.0 2.6 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain DUF3716 PF12511.3 GAP88641.1 - 0.11 12.0 4.0 0.21 11.2 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Cas_CXXC_CXXC PF09706.5 GAP88641.1 - 0.16 12.1 2.2 0.3 11.3 1.5 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_CXXC_CXXC) LSM PF01423.17 GAP88642.1 - 1.5e-18 66.0 0.2 1.8e-18 65.8 0.2 1.1 1 0 0 1 1 1 1 LSM domain PRMT5 PF05185.11 GAP88643.1 - 4.9e-55 187.2 0.0 5.6e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Amidase PF01425.16 GAP88643.1 - 0.14 11.0 0.6 0.18 10.5 0.4 1.1 1 0 0 1 1 1 0 Amidase PRMT5 PF05185.11 GAP88644.1 - 8.8e-97 324.8 0.0 1.1e-96 324.5 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Prefoldin_2 PF01920.15 GAP88645.1 - 4.6e-25 87.4 4.3 6e-25 87.0 3.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit AAA_23 PF13476.1 GAP88645.1 - 0.12 12.7 5.9 0.14 12.4 4.1 1.1 1 0 0 1 1 1 0 AAA domain DUF2730 PF10805.3 GAP88645.1 - 0.17 11.5 3.6 2.7 7.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) APG6 PF04111.7 GAP88645.1 - 2.3 7.1 8.7 7.8 5.4 3.6 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 bZIP_1 PF00170.16 GAP88645.1 - 5.5 7.0 8.5 0.65 9.9 0.4 2.3 2 0 0 2 2 2 0 bZIP transcription factor Cauli_AT PF03233.8 GAP88645.1 - 7.1 6.3 6.9 13 5.4 3.2 1.9 2 0 0 2 2 2 0 Aphid transmission protein Spc24 PF08286.6 GAP88645.1 - 7.3 6.3 10.0 3.7 7.2 0.1 2.3 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Seryl_tRNA_N PF02403.17 GAP88645.1 - 9.9 6.2 11.5 10 6.1 0.2 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2183 PF09949.4 GAP88646.1 - 6.9e-20 70.8 0.1 1.2e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) OB_NTP_bind PF07717.11 GAP88648.1 - 2.9e-26 91.5 0.1 7.9e-26 90.1 0.0 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 GAP88648.1 - 5.1e-23 81.0 0.1 1.1e-22 79.9 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 GAP88648.1 - 1.5e-09 37.6 0.0 3.6e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAP88648.1 - 7.5e-09 35.3 0.2 1.5e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAP88648.1 - 3.6e-06 27.1 0.0 1.1e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 GAP88648.1 - 0.00023 20.6 0.1 0.00061 19.2 0.0 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Pox_I1 PF03289.8 GAP88648.1 - 0.00086 18.2 0.1 0.0016 17.3 0.1 1.3 1 0 0 1 1 1 1 Poxvirus protein I1 T2SE PF00437.15 GAP88648.1 - 0.0016 17.3 0.2 0.0035 16.3 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein ResIII PF04851.10 GAP88648.1 - 0.0056 16.5 0.0 2.6 7.8 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_30 PF13604.1 GAP88648.1 - 0.0069 15.9 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 GAP88648.1 - 0.007 16.1 0.2 0.017 14.9 0.1 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain PhoH PF02562.11 GAP88648.1 - 0.096 11.9 0.0 0.44 9.7 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein JmjC PF02373.17 GAP88649.1 - 2.4e-36 124.4 0.5 8.9e-36 122.6 0.3 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 GAP88649.1 - 4.7e-19 68.4 5.1 8.5e-19 67.5 3.5 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 GAP88649.1 - 2.4e-18 66.0 5.6 6.1e-18 64.7 3.9 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.12 GAP88649.1 - 8.1e-15 54.0 1.5 1.6e-14 53.1 1.1 1.5 1 0 0 1 1 1 1 jmjN domain CENP-B_dimeris PF09026.5 GAP88649.1 - 0.017 15.3 5.8 0.049 13.8 4.0 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.7 GAP88649.1 - 0.17 9.7 4.6 0.26 9.1 3.2 1.1 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.6 GAP88649.1 - 0.56 9.1 7.0 1 8.2 4.8 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Sigma70_ner PF04546.8 GAP88649.1 - 1.5 8.4 5.9 2.8 7.5 4.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 GAP88649.1 - 5.2 4.9 6.7 8.1 4.3 4.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF601 PF04642.7 GAP88652.1 - 0.13 11.5 10.3 0.16 11.3 7.2 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF601 SRP-alpha_N PF04086.8 GAP88652.1 - 0.97 8.7 8.7 1.1 8.5 6.0 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MFS_1 PF07690.11 GAP88653.1 - 3.3e-36 124.7 30.4 6.9e-36 123.6 21.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP88653.1 - 2.1e-11 43.0 20.7 2.4e-11 42.8 14.1 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter 2OG-FeII_Oxy PF03171.15 GAP88654.1 - 5e-06 26.7 0.0 1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 GAP88654.1 - 0.00014 22.3 0.1 0.00033 21.0 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Thioredoxin_6 PF13848.1 GAP88655.1 - 2.8e-21 76.1 0.0 1.5e-18 67.2 0.0 2.2 1 1 2 3 3 3 3 Thioredoxin-like domain Thioredoxin PF00085.15 GAP88655.1 - 5.2e-14 51.7 0.0 8.9e-12 44.6 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin Rep_fac_C PF08542.6 GAP88656.1 - 7.9e-18 64.2 0.1 2.2e-17 62.8 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.24 GAP88656.1 - 6.2e-16 58.8 0.0 1.1e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 GAP88656.1 - 6.1e-13 48.7 0.0 2.9e-12 46.5 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 GAP88656.1 - 1.4e-09 37.2 0.0 2.5e-07 29.7 0.0 2.4 1 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 GAP88656.1 - 5.3e-07 29.7 0.0 3.9e-05 23.7 0.0 2.8 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAP88656.1 - 6.6e-07 29.5 0.1 3.5e-06 27.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAP88656.1 - 3.4e-06 26.7 0.0 8.4e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 GAP88656.1 - 7.1e-06 25.7 0.0 1.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 GAP88656.1 - 8.5e-06 25.5 0.2 2.8e-05 23.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 GAP88656.1 - 9.1e-06 24.6 0.0 0.053 12.2 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus DUF815 PF05673.8 GAP88656.1 - 1.7e-05 23.8 0.0 2.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 GAP88656.1 - 2.1e-05 23.6 0.2 0.00017 20.6 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 GAP88656.1 - 6.1e-05 22.9 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAP88656.1 - 6.3e-05 22.6 0.1 0.0005 19.7 0.0 2.0 1 1 1 2 2 2 1 AAA domain DNA_pol3_delta PF06144.8 GAP88656.1 - 6.9e-05 22.4 0.1 0.00011 21.7 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_3 PF07726.6 GAP88656.1 - 8.7e-05 22.1 0.1 0.00029 20.4 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 GAP88656.1 - 0.00025 20.3 0.4 0.24 10.6 0.0 2.6 2 1 1 3 3 3 2 PhoH-like protein Sigma54_activat PF00158.21 GAP88656.1 - 0.00043 19.7 0.0 0.00078 18.9 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_24 PF13479.1 GAP88656.1 - 0.0011 18.5 0.0 0.0024 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 GAP88656.1 - 0.0025 17.3 0.0 0.033 13.6 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_28 PF13521.1 GAP88656.1 - 0.0039 17.1 0.0 0.0081 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 GAP88656.1 - 0.0053 16.1 0.0 0.013 14.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 GAP88656.1 - 0.0061 15.5 0.0 0.0095 14.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 GAP88656.1 - 0.0089 15.4 0.0 0.14 11.5 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 GAP88656.1 - 0.01 15.0 0.1 0.05 12.7 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI SNF2_N PF00176.18 GAP88656.1 - 0.01 14.6 0.0 1.7 7.3 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain DEAD PF00270.24 GAP88656.1 - 0.01 15.3 0.0 0.46 9.9 0.0 2.8 2 1 1 3 3 3 0 DEAD/DEAH box helicase AAA_10 PF12846.2 GAP88656.1 - 0.017 14.5 0.2 0.79 9.0 0.1 2.4 1 1 0 1 1 1 0 AAA-like domain AAA_18 PF13238.1 GAP88656.1 - 0.021 15.0 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAP88656.1 - 0.024 15.4 0.0 0.067 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 GAP88656.1 - 0.04 13.7 0.0 0.2 11.4 0.0 1.9 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 GAP88656.1 - 0.053 13.6 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase GCS2 PF04107.8 GAP88656.1 - 0.084 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) Arch_ATPase PF01637.13 GAP88656.1 - 0.14 11.7 0.0 0.28 10.8 0.0 1.4 1 1 0 1 1 1 0 Archaeal ATPase VTC PF09359.5 GAP88656.1 - 0.15 11.0 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 VTC domain StbA PF06406.6 GAP88656.1 - 0.37 9.6 1.9 8.5 5.2 0.1 2.2 2 0 0 2 2 2 0 StbA protein Histone PF00125.19 GAP88658.1 - 2.1e-22 78.9 0.1 2.8e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 GAP88658.1 - 4.3e-05 23.4 0.0 6.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone R3H PF01424.17 GAP88659.1 - 1.4e-09 37.5 0.0 2.7e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 GAP88659.1 - 4.9e-06 26.4 0.1 9e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP88659.1 - 3.8e-05 23.4 0.1 7.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAP88659.1 - 0.00055 19.5 0.0 0.00099 18.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3176 PF11374.3 GAP88660.1 - 4.4e-29 100.5 0.8 9.3e-24 83.4 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3176) adh_short PF00106.20 GAP88661.1 - 1.9e-06 27.9 4.5 3.3e-06 27.1 3.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP88661.1 - 0.00045 19.9 2.2 0.00082 19.0 1.5 1.4 1 0 0 1 1 1 1 KR domain Methyltransf_26 PF13659.1 GAP88661.1 - 0.0063 16.5 1.4 0.012 15.5 1.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_10 PF13460.1 GAP88661.1 - 0.11 12.5 2.5 0.43 10.5 1.8 1.9 1 1 0 1 1 1 0 NADH(P)-binding Striatin PF08232.7 GAP88663.1 - 2.4e-34 118.5 0.5 2.4e-34 118.5 0.3 1.7 2 0 0 2 2 2 1 Striatin family WD40 PF00400.27 GAP88663.1 - 5.5e-30 102.1 15.0 2.3e-06 27.2 0.1 6.7 6 1 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 GAP88663.1 - 0.054 13.1 0.0 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A 4HBT PF03061.17 GAP88664.1 - 9.2e-12 44.9 0.1 1.4e-11 44.3 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 GAP88664.1 - 3.9e-05 23.5 0.4 8.6e-05 22.4 0.2 1.6 1 1 1 2 2 2 1 Thioesterase-like superfamily DUF4129 PF13559.1 GAP88665.1 - 8.5e-07 28.8 1.9 2.8e-06 27.2 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4129) DUF3923 PF13061.1 GAP88665.1 - 0.36 10.7 10.2 0.62 9.9 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3923) NICE-3 PF07406.6 GAP88665.1 - 0.4 10.1 8.3 1.4 8.3 0.1 2.4 3 0 0 3 3 3 0 NICE-3 protein DUF805 PF05656.9 GAP88665.1 - 0.8 9.5 5.5 1.4 8.7 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF805) DUF3753 PF12575.3 GAP88665.1 - 3 7.7 11.8 0.15 11.9 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Ndc1_Nup PF09531.5 GAP88666.1 - 9.7e-122 407.3 0.0 1.1e-121 407.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.1 GAP88667.1 - 4.1e-23 81.3 1.4 4.1e-23 81.3 1.0 2.3 2 0 0 2 2 2 2 Syntaxin-like protein SNARE PF05739.14 GAP88667.1 - 3.1e-15 55.5 4.4 1e-14 53.9 3.1 1.9 1 0 0 1 1 1 1 SNARE domain Synaptobrevin PF00957.16 GAP88667.1 - 0.008 15.7 0.3 0.087 12.4 0.1 2.4 2 0 0 2 2 2 1 Synaptobrevin TMPIT PF07851.8 GAP88667.1 - 0.073 12.1 4.8 0.074 12.1 1.5 1.9 1 1 2 3 3 3 0 TMPIT-like protein Spectrin PF00435.16 GAP88667.1 - 0.29 11.4 12.8 0.69 10.2 7.7 2.2 1 1 1 2 2 2 0 Spectrin repeat DUF1664 PF07889.7 GAP88667.1 - 0.31 10.8 5.0 0.43 10.3 1.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) 60KD_IMP PF02096.15 GAP88668.1 - 9.3e-07 28.6 0.1 6e-06 26.0 0.1 1.9 1 1 0 1 1 1 1 60Kd inner membrane protein Glycos_transf_1 PF00534.15 GAP88670.1 - 3.6e-18 65.5 0.0 5.2e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 GAP88670.1 - 1.2e-06 28.7 0.0 6.6e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 GAP88670.1 - 0.0055 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 G_glu_transpept PF01019.16 GAP88671.1 - 1.5e-154 515.2 2.4 1.9e-154 514.9 1.7 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase tRNA_U5-meth_tr PF05958.6 GAP88672.1 - 2e-08 33.3 0.0 0.0004 19.1 0.0 3.2 3 0 0 3 3 3 2 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 GAP88672.1 - 0.00016 21.3 0.0 0.00032 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.15 GAP88672.1 - 0.0088 15.8 0.2 0.02 14.6 0.1 1.5 1 0 0 1 1 1 1 TRAM domain Methyltransf_18 PF12847.2 GAP88672.1 - 0.012 16.1 0.1 0.027 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 GAP88672.1 - 0.017 14.2 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 GAP88672.1 - 0.038 14.0 0.3 0.08 12.9 0.2 1.6 1 0 0 1 1 1 0 Methyltransferase domain UNC45-central PF11701.3 GAP88673.1 - 8.6e-40 135.9 0.4 1.2e-37 128.9 0.0 3.8 3 2 1 4 4 4 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.1 GAP88673.1 - 0.0018 18.4 19.3 0.88 9.8 0.7 6.0 3 3 2 5 5 5 2 HEAT repeats YjgP_YjgQ PF03739.9 GAP88673.1 - 0.063 12.0 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Arm PF00514.18 GAP88673.1 - 0.26 11.1 11.5 50 3.9 0.0 6.8 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 GAP88673.1 - 1 9.9 13.9 33 5.1 0.2 6.1 5 1 0 5 5 5 0 HEAT-like repeat Tfb4 PF03850.9 GAP88674.1 - 5.2e-88 294.9 0.0 6e-88 294.6 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Asparaginase_2 PF01112.13 GAP88675.1 - 3.7e-36 124.4 3.6 2.5e-21 75.7 0.0 2.1 2 0 0 2 2 2 2 Asparaginase Actin PF00022.14 GAP88676.1 - 2.1e-88 296.3 0.0 4.7e-88 295.2 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 GAP88676.1 - 0.091 11.3 0.0 3.3 6.2 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Fungal_trans_2 PF11951.3 GAP88677.1 - 9.2e-09 34.3 0.5 1.3e-08 33.8 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP88677.1 - 9.4e-08 31.8 10.0 2.2e-07 30.6 6.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 GAP88678.1 - 9.3e-54 182.4 34.0 9.3e-54 182.4 23.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP88678.1 - 8.7e-13 47.6 12.6 8.7e-13 47.6 8.8 3.0 2 1 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.8 GAP88678.1 - 1e-05 23.8 1.6 1.6e-05 23.2 1.1 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector BT1 PF03092.11 GAP88678.1 - 0.0024 16.6 1.5 0.004 15.9 1.1 1.4 1 0 0 1 1 1 1 BT1 family p450 PF00067.17 GAP88679.1 - 3.1e-67 227.0 0.0 3.6e-67 226.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HNH_2 PF13391.1 GAP88680.1 - 2.3e-08 33.6 0.5 5.2e-08 32.5 0.3 1.6 1 0 0 1 1 1 1 HNH endonuclease FAD_binding_4 PF01565.18 GAP88681.1 - 3.2e-17 62.3 1.5 3.2e-17 62.3 1.0 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 GAP88681.1 - 8.9e-12 44.7 0.3 2.8e-11 43.1 0.2 1.9 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 GAP88681.1 - 0.0084 15.2 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding ketoacyl-synt PF00109.21 GAP88682.1 - 2.9e-63 213.7 0.3 7e-63 212.4 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 GAP88682.1 - 6.1e-56 188.9 0.0 1.9e-55 187.3 0.0 1.9 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 GAP88682.1 - 1.4e-45 155.9 0.1 7e-45 153.7 0.0 2.0 1 1 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 GAP88682.1 - 8.9e-44 149.3 0.0 3.8e-43 147.2 0.0 2.2 1 0 0 1 1 1 1 short chain dehydrogenase PS-DH PF14765.1 GAP88682.1 - 4.3e-38 131.1 0.0 7e-37 127.1 0.0 2.5 2 0 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 GAP88682.1 - 5e-36 123.1 0.0 1.5e-35 121.6 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 GAP88682.1 - 1.2e-14 54.5 0.0 3e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP88682.1 - 7.3e-09 35.3 0.0 3.4e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP88682.1 - 5.5e-08 32.6 0.0 1.6e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP88682.1 - 1.1e-07 32.2 0.0 2.8e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP88682.1 - 8.7e-07 29.5 0.3 4.5e-06 27.2 0.0 2.5 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP88682.1 - 9.2e-05 22.7 0.1 0.00028 21.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 GAP88682.1 - 0.00028 21.0 0.0 0.00077 19.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 GAP88682.1 - 0.00096 18.3 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 GAP88682.1 - 0.022 13.7 0.2 0.039 12.9 0.1 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain Glyco_hydro_42M PF08532.5 GAP88682.1 - 0.39 9.8 0.0 0.9 8.6 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain PCMT PF01135.14 GAP88682.1 - 0.48 9.9 0.0 1.7 8.1 0.0 1.9 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 GAP88682.1 - 0.74 8.7 0.0 1.6 7.6 0.0 1.5 1 1 0 1 1 1 0 Ribosomal RNA adenine dimethylase FSH1 PF03959.8 GAP88683.1 - 3.4e-33 114.8 0.0 4.1e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 GAP88683.1 - 3.5e-07 30.3 0.4 0.00044 20.1 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP88683.1 - 0.00029 20.6 0.0 0.00051 19.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family adh_short_C2 PF13561.1 GAP88684.1 - 1.4e-24 87.1 0.1 1.8e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAP88684.1 - 8.6e-22 77.8 2.4 1.5e-21 77.0 1.6 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP88684.1 - 1.7e-09 37.5 0.1 1.7e-09 37.5 0.0 1.4 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 GAP88684.1 - 0.003 16.5 0.0 0.0048 15.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.18 GAP88684.1 - 0.012 15.4 0.4 0.025 14.3 0.3 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DFP PF04127.10 GAP88684.1 - 0.017 14.7 0.1 0.78 9.3 0.0 2.2 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein ThiF PF00899.16 GAP88684.1 - 0.11 12.3 1.4 0.27 11.0 1.0 1.7 1 0 0 1 1 1 0 ThiF family MFS_1 PF07690.11 GAP88686.1 - 2.5e-29 102.0 42.7 5e-29 101.1 29.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP88686.1 - 3.9e-08 32.3 7.8 3.9e-08 32.3 5.4 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter CMD PF02627.15 GAP88687.1 - 0.00065 19.4 0.0 0.0014 18.4 0.0 1.6 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family FAD_binding_3 PF01494.14 GAP88688.1 - 1e-12 47.7 3.0 7.8e-05 21.8 0.1 3.1 2 1 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.19 GAP88688.1 - 3.3e-05 22.9 0.0 4.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 GAP88688.1 - 9.8e-05 22.6 1.0 0.0002 21.6 0.7 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAP88688.1 - 0.00015 20.3 0.8 0.00021 19.8 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 GAP88688.1 - 0.00035 20.5 0.2 0.00096 19.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAP88688.1 - 0.00066 19.6 0.0 0.0014 18.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAP88688.1 - 0.0012 17.8 0.2 0.0086 15.0 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAP88688.1 - 0.019 13.9 0.4 2.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.2 GAP88688.1 - 0.088 11.8 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 GAP88688.1 - 0.24 10.1 0.4 0.36 9.6 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A GMC_oxred_N PF00732.14 GAP88689.1 - 4.1e-63 213.2 0.0 7.2e-63 212.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAP88689.1 - 1e-31 110.1 0.0 1.8e-31 109.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 GAP88689.1 - 1.2e-05 24.4 0.6 2e-05 23.7 0.4 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 GAP88689.1 - 0.0025 16.7 0.3 0.085 11.7 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAP88689.1 - 0.012 14.7 0.4 0.16 11.0 0.1 2.3 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 GAP88689.1 - 0.017 13.9 1.0 1.7 7.3 0.4 2.1 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.9 GAP88689.1 - 0.064 11.8 0.0 0.098 11.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Peptidase_S8 PF00082.17 GAP88690.1 - 1.5e-12 47.2 0.0 2.9e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Subtilase family Pkinase PF00069.20 GAP88691.1 - 2.3e-27 95.7 0.0 4.2e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP88691.1 - 5.1e-17 61.8 0.0 8.6e-17 61.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HET PF06985.6 GAP88691.1 - 7.2e-13 48.8 0.0 1.4e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PolyG_pol PF01518.11 GAP88691.1 - 0.067 11.6 0.1 0.38 9.1 0.0 2.0 2 0 0 2 2 2 0 Sigma NS protein Pox_ser-thr_kin PF05445.6 GAP88691.1 - 0.15 10.7 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TPR_12 PF13424.1 GAP88695.1 - 4.1e-21 74.7 1.4 3.9e-08 33.1 0.3 4.9 2 1 3 5 5 5 5 Tetratricopeptide repeat NB-ARC PF00931.17 GAP88695.1 - 8.7e-14 51.0 0.0 1.4e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.1 GAP88695.1 - 9.9e-09 34.8 8.0 3.6e-05 23.5 0.0 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAP88695.1 - 4.6e-06 25.9 0.6 0.15 11.7 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAP88695.1 - 1.1e-05 25.7 0.3 0.9 9.9 0.0 4.0 2 1 1 3 3 3 2 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 GAP88695.1 - 1.9e-05 24.6 3.2 4.6e-05 23.4 2.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family TPR_7 PF13176.1 GAP88695.1 - 3e-05 23.5 0.0 1.4 8.9 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat AAA_16 PF13191.1 GAP88695.1 - 3.6e-05 23.8 0.0 0.0064 16.5 0.0 3.5 4 0 0 4 4 4 1 AAA ATPase domain TPR_14 PF13428.1 GAP88695.1 - 5.5e-05 23.4 5.9 7.5 7.4 0.2 6.3 6 1 1 7 7 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 GAP88695.1 - 0.00059 19.4 0.3 0.6 9.7 0.3 3.6 2 1 3 5 5 5 2 TPR repeat TPR_2 PF07719.12 GAP88695.1 - 0.00093 18.9 3.4 0.52 10.3 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.7 GAP88695.1 - 0.0011 18.7 0.1 0.24 11.2 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 GAP88695.1 - 0.0013 18.9 3.1 0.18 12.3 0.0 4.2 4 0 0 4 4 2 1 Tetratricopeptide repeat AAA_22 PF13401.1 GAP88695.1 - 0.0046 17.1 0.0 0.045 13.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain TPR_16 PF13432.1 GAP88695.1 - 0.013 16.1 2.3 4.3 8.1 0.0 4.3 3 1 1 4 4 3 0 Tetratricopeptide repeat PGAP1 PF07819.8 GAP88695.1 - 0.016 14.7 0.0 0.037 13.6 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein AAA_5 PF07728.9 GAP88695.1 - 0.018 14.7 0.0 0.16 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Abhydrolase_5 PF12695.2 GAP88695.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.9 GAP88695.1 - 0.12 11.6 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Arch_ATPase PF01637.13 GAP88695.1 - 0.23 11.1 0.0 0.62 9.7 0.0 1.7 2 0 0 2 2 1 0 Archaeal ATPase CHAT PF12770.2 GAP88696.1 - 1.2e-07 31.1 0.0 2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 CHAT domain DUF1632 PF07857.7 GAP88696.1 - 0.92 8.7 3.4 1.4 8.0 2.3 1.2 1 0 0 1 1 1 0 CEO family (DUF1632) PLA2_B PF01735.13 GAP88698.1 - 2e-193 643.0 0.0 2.3e-193 642.8 0.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Myc_N PF01056.13 GAP88700.1 - 0.016 14.3 0.1 0.025 13.7 0.1 1.3 1 0 0 1 1 1 0 Myc amino-terminal region DUF2293 PF10056.4 GAP88700.1 - 0.046 13.7 2.3 0.055 13.4 0.4 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2293) PBP1_TM PF14812.1 GAP88700.1 - 9.9 6.5 12.8 0.35 11.1 3.7 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Asp PF00026.18 GAP88701.1 - 1.6e-73 247.7 0.2 1.9e-73 247.5 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 GAP88701.1 - 5.9e-07 29.9 0.7 0.0014 19.1 0.4 2.9 3 1 0 3 3 3 2 Aspartyl protease TAXi_N PF14543.1 GAP88701.1 - 2e-05 24.6 0.0 0.00042 20.3 0.0 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Cation_efflux PF01545.16 GAP88702.1 - 1.1e-76 257.6 9.2 3.3e-76 256.0 6.4 1.6 1 1 0 1 1 1 1 Cation efflux family AsnC_trans_reg PF01037.16 GAP88702.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 AsnC family Glyoxalase PF00903.20 GAP88703.1 - 1.2e-15 57.5 0.0 1.6e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAP88703.1 - 6.9e-11 42.7 0.0 1.3e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 GAP88703.1 - 0.12 12.4 0.0 0.78 9.7 0.0 2.1 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyco_hydro_3 PF00933.16 GAP88704.1 - 1.6e-86 289.9 0.0 2.3e-86 289.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAP88704.1 - 2.9e-66 223.2 0.0 4.5e-66 222.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAP88704.1 - 2.7e-23 81.6 0.1 5.5e-23 80.6 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 GAP88704.1 - 1.8e-19 69.8 0.0 3.1e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Metallophos PF00149.23 GAP88705.1 - 5.8e-13 48.7 8.7 2.7e-12 46.5 6.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Sugar_tr PF00083.19 GAP88706.1 - 1.1e-118 396.7 24.3 1.3e-118 396.5 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP88706.1 - 4.2e-19 68.4 41.7 3.5e-13 48.9 10.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_2 PF00890.19 GAP88707.1 - 4.6e-85 285.9 1.5 7e-85 285.3 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 GAP88707.1 - 8.6e-22 76.7 0.2 8.6e-20 70.3 0.0 3.6 4 0 0 4 4 4 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 GAP88707.1 - 9.4e-14 51.0 2.7 3.7e-13 49.1 1.8 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 GAP88707.1 - 1.2e-09 37.8 0.5 4.1e-09 36.0 0.3 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAP88707.1 - 1.3e-08 34.7 2.4 1.1e-07 31.7 0.3 3.1 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAP88707.1 - 2.3e-08 34.1 0.0 1.6e-06 28.1 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAP88707.1 - 2.8e-06 26.0 3.3 0.004 15.6 0.1 3.5 3 1 0 3 3 3 2 HI0933-like protein Thi4 PF01946.12 GAP88707.1 - 1.7e-05 24.0 0.7 0.0059 15.7 0.1 2.7 3 0 0 3 3 3 2 Thi4 family FAD_binding_3 PF01494.14 GAP88707.1 - 0.00039 19.5 1.7 0.0065 15.5 0.5 2.2 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 GAP88707.1 - 0.00095 18.1 2.2 0.068 12.0 0.4 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.19 GAP88707.1 - 0.0013 17.9 0.7 0.21 10.6 0.1 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 GAP88707.1 - 0.16 11.9 4.3 0.079 13.0 0.7 2.3 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAP88707.1 - 0.31 11.4 4.4 2.1 8.7 1.1 2.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fasciclin PF02469.17 GAP88708.1 - 0.088 12.8 0.0 0.15 12.0 0.0 1.5 1 1 0 1 1 1 0 Fasciclin domain PAH PF02671.16 GAP88709.1 - 1.6e-47 158.8 2.7 2.6e-18 65.3 0.3 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 GAP88709.1 - 3.1e-38 129.5 0.1 1.3e-37 127.5 0.0 2.1 2 0 0 2 2 2 1 Sin3 family co-repressor Thiolase_N PF00108.18 GAP88710.1 - 3.7e-99 331.0 0.5 5.1e-99 330.5 0.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAP88710.1 - 1.5e-45 153.5 0.8 3.3e-45 152.4 0.5 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 GAP88710.1 - 0.00062 19.3 0.5 0.00062 19.3 0.4 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 GAP88710.1 - 0.57 9.8 4.0 1.1 8.9 0.0 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GTP_EFTU PF00009.22 GAP88711.1 - 1.1e-42 145.6 0.0 1.5e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 GAP88711.1 - 4.7e-27 93.9 0.0 1.3e-26 92.5 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 GAP88711.1 - 5.2e-17 61.4 0.0 1.6e-16 59.9 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 GAP88711.1 - 8.5e-08 32.2 0.0 2e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 GAP88711.1 - 8.3e-07 28.7 0.0 1.8e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 GAP88711.1 - 3.3e-05 23.8 0.1 6.2e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAP88711.1 - 0.0021 18.5 0.1 0.0055 17.2 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 GAP88711.1 - 0.28 9.8 0.1 0.52 8.9 0.1 1.4 1 0 0 1 1 1 0 G-protein alpha subunit DUF59 PF01883.14 GAP88712.1 - 3.5e-07 30.1 0.0 1.1e-06 28.4 0.0 1.9 2 1 0 2 2 2 1 Domain of unknown function DUF59 Fungal_trans PF04082.13 GAP88713.1 - 7.5e-16 57.7 0.1 1.2e-15 57.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP88713.1 - 2.3e-07 30.6 9.0 5.5e-07 29.3 6.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Esterase_phd PF10503.4 GAP88714.1 - 3.3e-21 75.5 3.6 3.3e-21 75.5 2.5 1.5 1 1 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.13 GAP88714.1 - 5.7e-15 54.6 7.5 3.1e-14 52.3 5.2 2.4 1 0 0 1 1 1 1 Fungal cellulose binding domain Peptidase_S9 PF00326.16 GAP88714.1 - 4.6e-12 45.6 1.0 7e-12 45.0 0.7 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAP88714.1 - 2.1e-07 30.7 0.5 4.6e-07 29.6 0.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP88714.1 - 1e-05 25.5 0.5 1.5e-05 25.0 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP88714.1 - 0.002 17.7 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 GAP88714.1 - 0.01 15.4 0.5 0.022 14.3 0.3 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.23 GAP88714.1 - 0.016 13.9 0.7 0.024 13.3 0.0 1.5 2 0 0 2 2 2 0 Carboxylesterase family Ank_2 PF12796.2 GAP88715.1 - 2.3e-29 101.5 0.0 6.8e-10 39.1 0.0 5.1 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAP88715.1 - 3.4e-21 73.9 0.1 0.0046 16.6 0.0 6.9 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.1 GAP88715.1 - 1.2e-19 68.3 0.0 0.0058 16.7 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 GAP88715.1 - 2.7e-16 59.1 0.4 0.025 14.8 0.0 6.9 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAP88715.1 - 1.8e-14 53.7 0.0 3.6e-06 27.3 0.0 5.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) p450 PF00067.17 GAP88716.1 - 1.2e-30 106.5 0.0 9.7e-21 73.8 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 Methyltransf_23 PF13489.1 GAP88717.1 - 5.1e-09 36.0 0.0 6.6e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP88717.1 - 1.5e-06 28.7 0.0 1.9e-05 25.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP88717.1 - 4.1e-06 27.1 0.0 1.2e-05 25.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP88717.1 - 4.2e-06 26.4 0.0 4.6e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP88717.1 - 5.5e-05 23.5 0.0 0.00011 22.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP88717.1 - 0.0017 18.6 0.0 0.0043 17.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP88717.1 - 0.0018 17.4 0.0 0.01 14.9 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.13 GAP88717.1 - 0.019 14.2 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_26 PF13659.1 GAP88717.1 - 0.036 14.0 0.0 0.15 12.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Abhydrolase_6 PF12697.2 GAP88718.1 - 4.7e-19 69.1 4.3 6.7e-19 68.6 3.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP88718.1 - 3.1e-09 36.7 2.2 3.9e-09 36.4 0.4 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP88718.1 - 0.00049 19.7 0.1 0.00093 18.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAP88718.1 - 0.0082 15.3 0.3 0.39 9.9 0.0 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 GAP88718.1 - 0.12 12.2 2.2 0.38 10.6 0.0 2.6 2 1 1 3 3 3 0 Putative lysophospholipase GST_N_3 PF13417.1 GAP88720.1 - 6.3e-12 45.5 0.0 1.2e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAP88720.1 - 5.2e-11 42.3 0.1 9.3e-11 41.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAP88720.1 - 1.8e-10 40.6 0.0 2.9e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAP88720.1 - 3.7e-10 39.8 0.0 6.7e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAP88720.1 - 0.00019 21.8 0.0 0.00032 21.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAP88720.1 - 0.00019 21.2 0.1 0.0004 20.2 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain p450 PF00067.17 GAP88721.1 - 1.9e-41 142.0 0.1 2.4e-41 141.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ada_Zn_binding PF02805.11 GAP88721.1 - 0.092 12.3 0.1 0.25 10.9 0.1 1.7 1 0 0 1 1 1 0 Metal binding domain of Ada Prenyltrans_1 PF13243.1 GAP88722.1 - 1.2e-07 31.6 0.1 0.012 15.5 0.1 3.8 3 0 0 3 3 3 2 Prenyltransferase-like Prenyltrans PF00432.16 GAP88722.1 - 0.01 15.4 3.4 3.6 7.2 0.0 4.2 4 0 0 4 4 4 2 Prenyltransferase and squalene oxidase repeat MBOAT PF03062.14 GAP88723.1 - 1.7e-44 152.2 23.5 1.7e-44 152.2 16.3 2.4 2 1 1 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family PufQ PF05398.6 GAP88723.1 - 0.0012 18.8 1.0 0.45 10.5 0.0 2.9 3 0 0 3 3 3 2 PufQ cytochrome subunit Far-17a_AIG1 PF04750.9 GAP88724.1 - 2.8e-08 33.1 10.6 4.1e-08 32.6 7.3 1.2 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Baculo_PEP_C PF04513.7 GAP88725.1 - 0.075 12.8 1.2 0.35 10.6 0.4 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FTO_CTD PF12934.2 GAP88725.1 - 0.19 11.2 2.0 11 5.5 0.0 3.6 3 1 1 4 4 4 0 FTO C-terminal domain MCPsignal PF00015.16 GAP88725.1 - 0.23 10.9 1.3 9.4 5.7 0.1 2.6 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain F-box-like PF12937.2 GAP88727.1 - 1.3e-10 40.8 0.0 3.6e-10 39.3 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 GAP88727.1 - 0.0075 15.8 0.2 0.015 14.9 0.1 1.5 1 0 0 1 1 1 1 F-box domain Mito_carr PF00153.22 GAP88728.1 - 9e-62 204.8 4.4 1.4e-20 72.8 0.1 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein UDG PF03167.14 GAP88729.1 - 6.8e-23 80.8 0.1 1e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF1708 PF08101.6 GAP88730.1 - 1.8e-158 527.8 0.0 2.2e-158 527.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) SRF-TF PF00319.13 GAP88731.1 - 4.8e-23 80.1 0.2 7.3e-23 79.5 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3591 PF12157.3 GAP88732.1 - 1.7e-174 580.5 0.2 2.6e-174 579.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 GAP88732.1 - 0.0028 17.3 0.6 0.0066 16.0 0.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 GAP88732.1 - 0.012 15.4 0.9 0.027 14.4 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle MerR-DNA-bind PF09278.6 GAP88732.1 - 0.053 13.9 0.0 0.18 12.2 0.0 1.9 1 0 0 1 1 1 0 MerR, DNA binding CytochromB561_N PF09786.4 GAP88732.1 - 2.3 6.5 6.1 0.6 8.4 1.7 1.7 2 0 0 2 2 2 0 Cytochrome B561, N terminal Sec61_beta PF03911.11 GAP88733.1 - 7.3e-21 73.6 1.5 9.4e-21 73.3 1.0 1.1 1 0 0 1 1 1 1 Sec61beta family DUF1180 PF06679.7 GAP88733.1 - 0.06 13.2 1.7 0.072 12.9 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) NAPRTase PF04095.11 GAP88734.1 - 4.5e-57 193.1 0.0 6e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family APH PF01636.18 GAP88735.1 - 3.6e-19 69.4 0.0 1.4e-18 67.4 0.0 2.0 2 2 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAP88735.1 - 0.00022 20.8 0.0 0.0016 18.0 0.0 2.2 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.17 GAP88735.1 - 0.0099 15.2 0.1 0.021 14.1 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Beta-lactamase PF00144.19 GAP88736.1 - 5.9e-54 183.3 0.0 1e-53 182.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase WD40 PF00400.27 GAP88736.1 - 5.5e-49 162.3 26.4 4.9e-12 45.2 0.9 11.0 12 0 0 12 12 11 6 WD domain, G-beta repeat NACHT PF05729.7 GAP88736.1 - 2.4e-11 43.5 0.0 5e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 GAP88736.1 - 4.9e-05 22.8 1.1 0.42 10.3 0.0 4.8 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat DUF3471 PF11954.3 GAP88736.1 - 0.0002 21.1 0.1 0.00047 19.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) AAA PF00004.24 GAP88736.1 - 0.00028 21.0 0.0 0.0011 19.1 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 GAP88736.1 - 0.00091 19.3 0.0 0.25 11.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase Miro PF08477.8 GAP88736.1 - 0.001 19.5 0.0 0.075 13.5 0.0 3.0 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 GAP88736.1 - 0.002 18.1 0.1 0.0071 16.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain IKI3 PF04762.7 GAP88736.1 - 0.016 13.0 0.0 0.72 7.5 0.0 2.3 2 0 0 2 2 2 0 IKI3 family AAA_25 PF13481.1 GAP88736.1 - 0.025 13.9 0.1 0.095 12.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 GAP88736.1 - 0.025 14.0 0.0 0.062 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 GAP88736.1 - 0.06 12.8 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_19 PF13245.1 GAP88736.1 - 0.073 12.8 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 GAP88736.1 - 0.086 13.1 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 GAP88736.1 - 0.13 11.0 0.0 0.24 10.1 0.0 1.4 1 0 0 1 1 1 0 ArgK protein KAP_NTPase PF07693.9 GAP88736.1 - 0.13 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_22 PF13401.1 GAP88736.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 GAP88736.1 - 0.16 10.8 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.9 GAP88736.1 - 0.22 11.2 0.0 0.58 9.8 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 GAP88736.1 - 0.26 10.9 0.0 0.45 10.2 0.0 1.3 1 0 0 1 1 1 0 NTPase Zeta_toxin PF06414.7 GAP88736.1 - 0.29 10.1 0.0 2.3 7.2 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.1 GAP88736.1 - 0.4 10.9 0.0 1.1 9.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain YodA PF09223.6 GAP88737.1 - 0.062 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 YodA lipocalin-like domain Peptidase_S8 PF00082.17 GAP88738.1 - 1.4e-15 57.1 0.4 1e-14 54.3 0.1 2.2 2 0 0 2 2 2 1 Subtilase family Ank_4 PF13637.1 GAP88738.1 - 2.4e-09 37.4 1.1 0.0014 19.0 0.1 5.1 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 GAP88738.1 - 1.6e-08 33.9 0.9 0.083 12.7 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 GAP88738.1 - 2.1e-08 33.6 1.0 0.12 12.6 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 GAP88738.1 - 7.7e-08 32.5 0.6 0.0013 19.0 0.1 3.2 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAP88738.1 - 0.00026 21.1 1.4 1 9.7 0.2 4.3 1 1 2 3 3 3 1 Ankyrin repeats (many copies) FAM222A PF15258.1 GAP88738.1 - 0.53 9.4 2.1 3.7 6.6 0.6 2.1 2 0 0 2 2 2 0 Protein family of FAM222A Ank_2 PF12796.2 GAP88740.1 - 3.3e-05 24.1 0.1 0.00097 19.4 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Peptidase_S8 PF00082.17 GAP88740.1 - 6e-05 22.3 0.0 9.8e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Subtilase family Ank_4 PF13637.1 GAP88740.1 - 0.00036 20.9 0.8 0.79 10.3 0.1 4.7 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP88740.1 - 0.0013 18.9 0.3 2.9 8.2 0.0 4.1 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP88740.1 - 0.0036 17.4 0.5 8.3 6.9 0.0 4.9 5 0 0 5 5 5 1 Ankyrin repeat BRE1 PF08647.6 GAP88740.1 - 0.13 12.2 0.1 2.1 8.3 0.1 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Fungal_trans PF04082.13 GAP88741.1 - 5.7e-15 54.9 0.3 1.3e-14 53.7 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP88741.1 - 2.7e-07 30.3 11.1 4.8e-07 29.5 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tyrosinase PF00264.15 GAP88742.1 - 6.5e-47 160.5 1.3 9e-47 160.0 0.9 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Uma2 PF05685.7 GAP88744.1 - 0.069 12.4 0.0 0.27 10.5 0.0 1.8 2 0 0 2 2 2 0 Putative restriction endonuclease Bac_rhodopsin PF01036.13 GAP88745.1 - 1.5e-57 194.4 13.2 2e-57 194.0 9.1 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein FixP_N PF14715.1 GAP88745.1 - 0.039 13.3 7.1 1.7 8.1 0.3 3.4 3 0 0 3 3 3 0 N-terminal domain of cytochrome oxidase-cbb3, FixP MARVEL PF01284.18 GAP88745.1 - 0.091 12.5 0.4 0.091 12.5 0.3 3.1 3 0 0 3 3 3 0 Membrane-associating domain DUF3784 PF12650.2 GAP88745.1 - 2.2 8.2 6.9 2.6 8.0 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF2784 PF10861.3 GAP88745.1 - 5.2 6.9 9.5 0.6 9.9 1.6 2.3 1 1 1 2 2 2 0 Protein of Unknown function (DUF2784) RPE65 PF03055.10 GAP88746.1 - 4.3e-80 269.6 0.0 5.4e-80 269.2 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Pkinase PF00069.20 GAP88746.1 - 3.9e-43 147.4 0.0 1e-42 146.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP88746.1 - 2.4e-30 105.4 0.0 3.4e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 GAP88746.1 - 0.0058 15.7 0.0 0.15 11.0 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 GAP88746.1 - 0.026 13.4 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Epimerase PF01370.16 GAP88747.1 - 1.7e-12 47.3 0.0 2.9e-12 46.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAP88747.1 - 2.3e-11 44.0 0.0 4.4e-11 43.1 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 GAP88747.1 - 5.8e-05 23.0 1.9 5.8e-05 23.0 1.3 2.6 2 1 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 GAP88747.1 - 0.0004 19.3 0.0 0.0017 17.3 0.0 2.0 3 0 0 3 3 3 1 RmlD substrate binding domain NmrA PF05368.8 GAP88747.1 - 0.0012 18.1 0.0 0.0039 16.4 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family Eno-Rase_NADH_b PF12242.3 GAP88747.1 - 0.0015 18.2 0.4 0.0085 15.8 0.3 2.2 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TFIIS_M PF07500.9 GAP88748.1 - 2.4e-26 92.0 0.8 5.9e-26 90.8 0.5 1.7 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 GAP88748.1 - 2.9e-17 62.0 6.9 6.1e-17 60.9 4.8 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 GAP88748.1 - 7.2e-12 44.6 0.2 1.6e-11 43.5 0.2 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain MTBP_C PF14920.1 GAP88748.1 - 0.02 14.3 3.2 0.035 13.6 2.2 1.3 1 0 0 1 1 1 0 MDM2-binding DUF678 PF05077.7 GAP88748.1 - 0.22 11.5 2.7 0.51 10.3 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF678) Evr1_Alr PF04777.8 GAP88748.1 - 0.95 9.4 5.1 0.61 10.0 1.6 2.1 2 0 0 2 2 2 0 Erv1 / Alr family PALP PF00291.20 GAP88749.1 - 4.4e-55 187.0 0.7 7.7e-55 186.2 0.5 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme KCl_Cotrans_1 PF03522.10 GAP88749.1 - 0.016 14.7 1.1 0.051 13.0 0.0 2.3 2 0 0 2 2 2 0 K-Cl Co-transporter type 1 (KCC1) Methyltransf_28 PF02636.12 GAP88750.1 - 2.1e-36 125.6 0.0 5.9e-36 124.1 0.0 1.7 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.11 GAP88750.1 - 0.014 14.3 0.0 0.031 13.2 0.0 1.5 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase tRNA-synt_2c PF01411.14 GAP88751.1 - 1.7e-211 703.2 0.6 2.6e-211 702.7 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 GAP88751.1 - 1.3e-15 56.9 0.4 3.1e-15 55.7 0.3 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 GAP88751.1 - 0.00027 20.5 0.3 0.0009 18.8 0.2 1.9 1 0 0 1 1 1 1 DHHA1 domain Macoilin PF09726.4 GAP88752.1 - 0.28 9.4 11.2 0.33 9.1 7.8 1.1 1 0 0 1 1 1 0 Transmembrane protein RCR PF12273.3 GAP88753.1 - 2.5e-09 37.7 2.0 3.1e-09 37.4 1.4 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red p450 PF00067.17 GAP88755.1 - 7e-34 117.1 0.0 8.3e-32 110.3 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.11 GAP88756.1 - 4.6e-39 134.1 48.6 4.6e-39 134.1 33.7 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAP88756.1 - 2.1e-14 52.6 12.0 2.1e-14 52.6 8.3 1.9 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Corona_S2 PF01601.11 GAP88756.1 - 0.38 8.8 3.4 0.53 8.3 2.4 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein p450 PF00067.17 GAP88757.1 - 3.1e-28 98.5 0.1 9e-26 90.4 0.0 2.8 2 1 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 GAP88758.1 - 1.9e-50 171.7 0.0 2.6e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sel1 PF08238.7 GAP88759.1 - 4.1e-44 148.0 38.4 4.2e-07 30.3 0.1 12.8 13 0 0 13 13 13 9 Sel1 repeat TPR_7 PF13176.1 GAP88759.1 - 1.1 9.2 7.8 4.3 7.3 0.2 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAP88759.1 - 7.8 6.2 12.6 11 5.8 0.1 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat WD40 PF00400.27 GAP88760.1 - 4.5e-07 29.5 3.7 0.028 14.3 0.0 4.2 4 1 0 4 4 4 2 WD domain, G-beta repeat FRG1 PF06229.7 GAP88761.1 - 2.9e-54 183.4 0.1 3.6e-54 183.1 0.1 1.1 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 GAP88761.1 - 0.019 15.0 0.0 0.15 12.2 0.0 2.2 2 1 1 3 3 3 0 Fascin domain TmoB PF06234.7 GAP88761.1 - 0.091 12.6 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 Toluene-4-monooxygenase system protein B (TmoB) 2OG-FeII_Oxy PF03171.15 GAP88762.1 - 0.0054 16.9 0.0 0.016 15.4 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2074 PF09847.4 GAP88763.1 - 0.0089 14.8 1.6 0.011 14.5 1.1 1.1 1 0 0 1 1 1 1 Predicted permease (DUF2074) DUF485 PF04341.7 GAP88763.1 - 1.4 8.6 5.1 0.37 10.5 0.7 2.1 3 0 0 3 3 3 0 Protein of unknown function, DUF485 Thioredoxin_4 PF13462.1 GAP88764.1 - 3.4e-07 30.4 0.0 6.3e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.15 GAP88764.1 - 0.11 12.0 3.3 1.9 7.9 0.1 2.9 1 1 0 2 2 2 0 DSBA-like thioredoxin domain Mur_ligase_M PF08245.7 GAP88765.1 - 0.012 15.7 0.1 0.12 12.3 0.0 2.4 2 1 0 2 2 2 0 Mur ligase middle domain Mur_ligase_C PF02875.16 GAP88765.1 - 0.085 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.7 GAP88766.1 - 0.07 13.1 0.1 2.2 8.3 0.4 2.5 3 0 0 3 3 3 0 Mur ligase middle domain Mitofilin PF09731.4 GAP88767.1 - 1.1e-29 103.5 1.5 1.2e-29 103.4 1.0 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Mitofilin PF09731.4 GAP88768.1 - 8.8e-74 249.1 4.8 1.2e-73 248.7 3.3 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF3829 PF12889.2 GAP88768.1 - 0.71 9.0 7.4 0.68 9.0 3.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) Ras PF00071.17 GAP88769.1 - 7.6e-59 197.7 0.2 8.8e-59 197.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAP88769.1 - 3.5e-19 69.4 0.1 6.2e-19 68.6 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAP88769.1 - 7e-16 57.9 0.0 8.7e-16 57.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAP88769.1 - 1.9e-08 33.9 0.0 2.7e-08 33.4 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAP88769.1 - 5.6e-08 32.1 0.0 6.9e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAP88769.1 - 1.2e-05 25.2 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 GAP88769.1 - 0.036 13.2 0.3 0.17 11.0 0.0 2.1 2 1 0 3 3 3 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAP88769.1 - 0.057 13.5 0.1 1.8 8.6 0.1 2.5 1 1 0 1 1 1 0 AAA domain Amidase02_C PF12123.3 GAP88769.1 - 0.11 12.1 0.0 0.82 9.3 0.0 2.1 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF2624 PF11116.3 GAP88769.1 - 0.11 12.9 0.7 9.2 6.8 0.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2624) AAA_16 PF13191.1 GAP88769.1 - 0.12 12.3 0.8 0.33 10.9 0.6 1.8 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.15 GAP88769.1 - 0.15 10.7 0.5 10 4.6 0.1 2.3 1 1 1 2 2 2 0 G-protein alpha subunit Syja_N PF02383.13 GAP88770.1 - 4.7e-88 295.0 0.0 5.9e-88 294.7 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain BTB PF00651.26 GAP88771.1 - 2.3e-08 33.9 0.0 1.2e-07 31.7 0.0 2.1 3 0 0 3 3 3 1 BTB/POZ domain PCI PF01399.22 GAP88772.1 - 7.5e-13 48.7 0.0 1.4e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 PCI domain Ribosomal_L18ae PF01775.12 GAP88773.1 - 3.5e-60 201.3 0.4 4.4e-60 201.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Fungal_trans PF04082.13 GAP88774.1 - 9e-23 80.4 0.1 1.8e-22 79.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_3 PF13302.1 GAP88775.1 - 8.1e-33 113.5 0.0 1e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAP88775.1 - 0.00012 22.1 0.0 0.54 10.1 0.0 3.0 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAP88775.1 - 0.0031 17.4 0.1 3.4 7.5 0.0 2.9 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAP88775.1 - 0.0044 17.0 0.1 0.46 10.5 0.1 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAP88775.1 - 0.033 13.9 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 FR47-like protein DUF1772 PF08592.6 GAP88776.1 - 3.5e-24 85.1 2.8 5e-24 84.6 2.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) zf-C2H2_4 PF13894.1 GAP88780.1 - 8.7e-07 28.8 8.9 0.0048 17.1 1.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 GAP88780.1 - 0.00031 20.9 8.5 0.02 15.2 1.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type HRDC PF00570.18 GAP88782.1 - 3.6e-21 74.6 0.0 1e-15 57.1 0.0 2.6 2 0 0 2 2 2 2 HRDC domain DNA_pol_A_exo1 PF01612.15 GAP88782.1 - 2.6e-15 56.3 0.0 4.3e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease HHH PF00633.18 GAP88782.1 - 0.00087 18.8 0.0 0.092 12.4 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix motif DUF2201_N PF13203.1 GAP88782.1 - 0.03 13.4 0.1 0.057 12.5 0.1 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain adh_short PF00106.20 GAP88783.1 - 2.4e-22 79.6 0.4 3.4e-22 79.1 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP88783.1 - 1.6e-10 40.9 0.1 2.2e-10 40.5 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAP88783.1 - 1.5e-06 28.3 1.0 1.8e-05 24.8 0.7 2.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 GAP88783.1 - 2.1e-05 24.4 0.0 2.8e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAP88783.1 - 0.011 15.2 0.1 0.042 13.2 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAP88783.1 - 0.026 13.7 0.3 0.85 8.8 0.1 2.6 2 1 1 3 3 3 0 NmrA-like family RPT PF13446.1 GAP88783.1 - 0.042 13.2 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 A repeated domain in UCH-protein T4_gp9_10 PF07880.6 GAP88783.1 - 0.098 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage T4 gp9/10-like protein Eno-Rase_NADH_b PF12242.3 GAP88783.1 - 0.34 10.7 1.5 0.58 9.9 0.1 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Vfa1 PF08432.5 GAP88784.1 - 0.014 15.4 11.3 0.02 14.9 7.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.7 GAP88784.1 - 0.048 11.5 28.8 0.058 11.3 20.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 GAP88784.1 - 0.058 12.1 24.4 0.099 11.3 16.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1656 PF07869.7 GAP88784.1 - 0.5 10.2 3.0 0.78 9.5 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) Pox_Ag35 PF03286.9 GAP88784.1 - 1.1 8.7 12.9 1.7 8.1 8.9 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Daxx PF03344.10 GAP88784.1 - 1.1 7.6 27.8 1.5 7.2 19.3 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 GAP88784.1 - 3 5.7 21.9 4.1 5.3 15.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Bromodomain PF00439.20 GAP88785.1 - 8.3e-21 73.7 0.1 1.4e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 GAP88785.1 - 6.6e-07 29.3 0.1 1.2e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAP88785.1 - 1.3e-05 25.0 0.1 3e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAP88785.1 - 0.014 15.5 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Rad1 PF02144.11 GAP88786.1 - 3.9e-79 265.2 0.0 4.4e-79 265.0 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Glyco_hydro_43 PF04616.9 GAP88789.1 - 5.1e-20 71.7 1.1 2.2e-15 56.4 0.1 2.7 3 0 0 3 3 3 2 Glycosyl hydrolases family 43 CDK2AP PF09806.4 GAP88789.1 - 0.011 16.0 2.4 0.018 15.3 1.7 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Pil1 PF13805.1 GAP88790.1 - 2.5e-154 512.2 0.3 3.5e-154 511.7 0.2 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 GAP88790.1 - 0.035 13.4 3.7 0.11 11.8 2.6 1.7 1 1 0 1 1 1 0 FAM92 protein SET PF00856.23 GAP88791.1 - 5.5e-23 82.0 0.3 5.5e-23 82.0 0.2 2.6 2 1 0 2 2 2 1 SET domain Fmp27_GFWDK PF10347.4 GAP88791.1 - 0.14 12.1 0.9 1.5 8.7 0.1 2.2 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF3494 PF11999.3 GAP88793.1 - 4.3e-44 150.5 19.4 5.1e-44 150.3 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) FAD_binding_3 PF01494.14 GAP88795.1 - 3.5e-23 82.2 0.0 5.9e-23 81.4 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAP88795.1 - 1.5e-06 27.3 0.1 0.0083 15.0 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAP88795.1 - 0.0015 18.8 0.0 0.078 13.3 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP88795.1 - 0.0016 18.5 0.0 0.0058 16.7 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAP88795.1 - 0.0071 16.2 0.2 0.018 14.9 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAP88795.1 - 0.0074 14.8 0.2 0.38 9.1 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein TrkA_N PF02254.13 GAP88795.1 - 0.0087 16.0 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Lycopene_cycl PF05834.7 GAP88795.1 - 0.012 14.6 0.0 0.04 12.8 0.0 1.8 1 1 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 GAP88795.1 - 0.025 13.6 0.0 0.053 12.6 0.0 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.1 GAP88795.1 - 0.058 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Ank_2 PF12796.2 GAP88797.1 - 1.8e-21 76.2 0.0 1.5e-11 44.4 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAP88797.1 - 1.6e-12 47.5 1.2 2.4e-06 27.9 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 GAP88797.1 - 2.1e-10 39.8 0.6 0.0076 16.0 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat TPR_12 PF13424.1 GAP88797.1 - 1.2e-09 37.9 4.4 3.6e-05 23.6 0.7 4.6 3 1 2 5 5 5 3 Tetratricopeptide repeat Ank_5 PF13857.1 GAP88797.1 - 6.8e-09 35.6 0.3 1.4e-05 25.1 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) CorA PF01544.13 GAP88797.1 - 2.6e-08 33.2 0.4 5.3e-08 32.2 0.3 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Ank_3 PF13606.1 GAP88797.1 - 8.3e-06 25.5 0.1 2 8.8 0.0 4.9 4 0 0 4 4 4 1 Ankyrin repeat TPR_2 PF07719.12 GAP88797.1 - 0.14 12.1 1.0 1.7 8.7 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Vfa1 PF08432.5 GAP88797.1 - 0.46 10.5 6.0 0.2 11.6 0.1 2.7 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 TPR_10 PF13374.1 GAP88797.1 - 0.87 9.6 10.9 22 5.1 0.0 6.4 7 1 1 8 8 8 0 Tetratricopeptide repeat Glyco_hydro_11 PF00457.12 GAP88798.1 - 4.5e-75 251.0 23.4 5.3e-75 250.7 16.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 XPG_N PF00752.12 GAP88799.1 - 7.2e-33 112.8 0.0 1.9e-32 111.5 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 GAP88799.1 - 5.7e-26 90.4 0.0 1.6e-25 88.9 0.0 1.8 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 GAP88799.1 - 0.038 14.2 0.0 0.15 12.2 0.0 2.1 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold LSM PF01423.17 GAP88800.1 - 1.2e-07 31.1 0.0 1.8e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 GAP88800.1 - 0.0078 16.1 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain Glyco_hydro_43 PF04616.9 GAP88801.1 - 5.1e-22 78.2 0.1 1.1e-21 77.2 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Aldedh PF00171.17 GAP88802.1 - 8.2e-132 439.8 0.5 9.9e-132 439.5 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short_C2 PF13561.1 GAP88803.1 - 4.5e-27 95.3 0.0 5.4e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAP88803.1 - 3.4e-24 85.6 4.3 4.5e-24 85.2 3.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP88803.1 - 9.6e-14 51.4 1.8 1.5e-13 50.8 1.2 1.3 1 0 0 1 1 1 1 KR domain APH PF01636.18 GAP88805.1 - 2.5e-15 56.8 0.0 5.7e-15 55.7 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 GAP88805.1 - 0.012 14.7 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.15 GAP88805.1 - 0.013 15.0 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Cellulase PF00150.13 GAP88806.1 - 1.7e-11 43.8 4.6 2.7e-11 43.2 3.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) BetaGal_dom4_5 PF13364.1 GAP88806.1 - 0.0077 16.4 0.7 0.016 15.4 0.1 1.8 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Cellulase-like PF12876.2 GAP88806.1 - 0.041 14.3 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 Sugar-binding cellulase-like His_Phos_2 PF00328.17 GAP88807.1 - 9.8e-23 81.0 0.0 1.2e-15 57.6 0.0 2.7 2 1 0 3 3 3 2 Histidine phosphatase superfamily (branch 2) LSM PF01423.17 GAP88810.1 - 4.4e-17 61.3 0.2 5.9e-17 60.9 0.2 1.2 1 0 0 1 1 1 1 LSM domain ATP13 PF12921.2 GAP88811.1 - 7.1e-14 51.2 0.1 1.9e-13 49.8 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ATPase expression PIG-L PF02585.12 GAP88812.1 - 6.7e-28 97.7 0.0 1.1e-27 97.0 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase AbbA_antirepres PF14156.1 GAP88813.1 - 0.023 14.3 0.1 0.05 13.2 0.1 1.5 1 0 0 1 1 1 0 Antirepressor AbbA CMV_1a PF12467.3 GAP88813.1 - 0.22 11.8 0.6 0.3 11.4 0.4 1.2 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Macoilin PF09726.4 GAP88815.1 - 0.11 10.7 0.0 0.13 10.5 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Sugar_tr PF00083.19 GAP88816.1 - 5.7e-80 269.0 21.9 6.7e-80 268.8 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP88816.1 - 1.7e-21 76.3 50.3 1.1e-15 57.1 15.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 GAP88816.1 - 1.4 8.9 11.0 2.1 8.4 0.3 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) p450 PF00067.17 GAP88817.1 - 1.8e-48 165.2 0.0 2.6e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_10 PF13460.1 GAP88818.1 - 1.1e-05 25.4 0.6 0.00044 20.3 0.0 2.3 1 1 1 2 2 2 2 NADH(P)-binding NmrA PF05368.8 GAP88818.1 - 3.6e-05 23.1 0.0 0.00034 19.9 0.0 2.0 1 1 1 2 2 2 1 NmrA-like family Semialdhyde_dh PF01118.19 GAP88818.1 - 0.0047 17.2 0.0 0.0095 16.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Herpes_VP19C PF03327.9 GAP88818.1 - 0.064 12.1 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus capsid shell protein VP19C DUF1522 PF07482.6 GAP88818.1 - 0.092 12.9 0.2 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1522) Y_phosphatase3C PF13348.1 GAP88818.1 - 0.13 12.3 0.9 0.47 10.5 0.2 2.2 2 0 0 2 2 2 0 Tyrosine phosphatase family C-terminal region Asp PF00026.18 GAP88819.1 - 3e-62 210.7 1.0 3.6e-62 210.4 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAP88819.1 - 4.8e-10 39.6 1.2 7.4e-10 39.0 0.0 1.9 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 GAP88819.1 - 0.041 14.3 0.5 4.1 7.9 0.0 2.9 3 0 0 3 3 3 0 Aspartyl protease NUDIX PF00293.23 GAP88820.1 - 5.8e-17 61.6 0.2 1e-16 60.8 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain SSP160 PF06933.6 GAP88820.1 - 1.9 6.3 7.6 2.3 6.1 5.3 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 COX5B PF01215.14 GAP88821.1 - 7.4e-38 129.2 0.0 9.4e-38 128.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.14 GAP88821.1 - 0.017 14.6 0.3 6.4 6.3 0.1 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Zn-ribbon_8 PF09723.5 GAP88821.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Zinc ribbon domain RRN7 PF11781.3 GAP88821.1 - 0.11 11.9 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 ADK_lid PF05191.9 GAP88821.1 - 0.13 11.9 1.3 0.25 11.0 0.9 1.5 1 0 0 1 1 1 0 Adenylate kinase, active site lid SRPRB PF09439.5 GAP88822.1 - 0.2 10.8 0.6 0.33 10.1 0.4 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit SelP_N PF04592.9 GAP88822.1 - 0.51 9.6 9.2 1.2 8.4 6.4 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 GAP88822.1 - 1.1 8.1 2.8 1.7 7.5 1.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ribosomal_S6 PF01250.12 GAP88823.1 - 3.3e-09 36.4 0.0 4e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 Cullin_binding PF03556.10 GAP88824.1 - 1.3e-28 99.5 2.5 2.3e-28 98.6 1.7 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 GAP88824.1 - 4.5e-09 35.7 0.0 2.3e-08 33.4 0.0 2.1 2 0 0 2 2 2 1 UBA-like domain PX PF00787.19 GAP88825.1 - 2e-16 59.7 0.0 4.3e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 PX domain Ribosomal_L18e PF00828.14 GAP88826.1 - 2.4e-18 66.7 0.5 3.9e-18 66.0 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Chorion_2 PF03964.10 GAP88826.1 - 0.0099 16.4 1.1 0.021 15.3 0.2 1.9 2 0 0 2 2 2 1 Chorion family 2 p450 PF00067.17 GAP88827.1 - 2.4e-58 197.7 0.0 3.1e-58 197.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 GAP88828.1 - 4.8e-12 45.2 12.1 5.8e-12 44.9 8.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_S26 PF10502.4 GAP88828.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 Signal peptidase, peptidase S26 CRCB PF02537.10 GAP88829.1 - 8e-31 106.3 12.0 9.2e-19 67.4 3.9 3.5 3 0 0 3 3 3 3 CrcB-like protein MFS_1 PF07690.11 GAP88829.1 - 3.3e-06 26.0 0.7 3.3e-06 26.0 0.5 3.0 2 1 1 3 3 3 1 Major Facilitator Superfamily UPRTase PF14681.1 GAP88830.1 - 1.3e-49 168.2 0.0 1.4e-49 168.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 GAP88830.1 - 5.6e-06 26.1 0.1 7.6e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain P5CR_dimer PF14748.1 GAP88830.1 - 0.012 15.5 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation Pribosyl_synth PF14572.1 GAP88830.1 - 0.025 14.3 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain PRTase_2 PF15609.1 GAP88830.1 - 0.05 12.9 0.0 0.06 12.6 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosyl transferase TMP-TENI PF02581.12 GAP88830.1 - 0.14 11.2 0.3 0.19 10.8 0.2 1.1 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI DNA_ligase_A_M PF01068.16 GAP88831.1 - 2.5e-43 147.8 0.0 6.2e-43 146.5 0.0 1.7 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 GAP88831.1 - 1.2e-36 126.1 0.0 2.8e-36 125.0 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 GAP88831.1 - 3e-13 49.9 1.0 6.9e-13 48.8 0.0 2.2 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 GAP88831.1 - 1.4e-11 44.3 0.0 5.7e-08 32.8 0.0 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain RNA_ligase PF09414.5 GAP88831.1 - 0.00017 21.4 0.0 0.00034 20.4 0.0 1.5 1 1 0 1 1 1 1 RNA ligase PIF1 PF05970.9 GAP88832.1 - 1.5e-60 205.0 0.1 3.3e-46 157.9 0.0 2.3 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 GAP88832.1 - 1.7e-18 66.9 0.0 3.3e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAP88832.1 - 4.7e-09 36.4 0.0 1.8e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAP88832.1 - 1.5e-05 24.6 0.3 4.8e-05 23.0 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain UvrD_C_2 PF13538.1 GAP88832.1 - 3e-05 24.0 0.1 0.00034 20.7 0.1 2.4 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 GAP88832.1 - 6.7e-05 22.9 0.1 0.00017 21.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Herpes_Helicase PF02689.9 GAP88832.1 - 0.00034 18.5 0.1 0.0014 16.4 0.0 1.8 2 0 0 2 2 2 1 Helicase AAA PF00004.24 GAP88832.1 - 0.00042 20.5 0.0 0.00093 19.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 GAP88832.1 - 0.0015 17.5 0.0 0.0024 16.8 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.22 GAP88832.1 - 0.0026 18.0 0.0 0.0068 16.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_11 PF13086.1 GAP88832.1 - 0.0032 17.0 0.0 0.16 11.5 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_10 PF12846.2 GAP88832.1 - 0.0083 15.5 0.2 0.11 11.9 0.1 2.2 2 0 0 2 2 2 1 AAA-like domain AAA_29 PF13555.1 GAP88832.1 - 0.01 15.3 0.0 0.024 14.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 GAP88832.1 - 0.016 15.3 0.0 0.041 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 GAP88832.1 - 0.016 15.1 0.0 0.055 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 GAP88832.1 - 0.022 14.4 0.0 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.11 GAP88832.1 - 0.023 13.9 0.0 0.052 12.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein MobB PF03205.9 GAP88832.1 - 0.039 13.6 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 GAP88832.1 - 0.062 12.9 0.0 0.17 11.5 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase DUF2075 PF09848.4 GAP88832.1 - 0.062 12.2 0.0 0.14 11.0 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 GAP88832.1 - 0.067 12.9 0.1 0.29 10.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 GAP88832.1 - 0.091 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 GAP88832.1 - 0.092 12.4 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 NTPase DUF258 PF03193.11 GAP88832.1 - 0.11 11.7 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 GAP88832.1 - 0.14 11.5 0.1 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein Zip PF02535.17 GAP88833.1 - 1.9e-55 188.1 3.0 3.2e-55 187.3 2.1 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter DUF3722 PF12519.3 GAP88834.1 - 9.5e-82 274.1 0.1 1.6e-81 273.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 GAP88834.1 - 2.8e-05 23.5 0.0 0.013 14.8 0.1 2.8 3 0 0 3 3 3 2 Eukaryotic porin adh_short PF00106.20 GAP88835.1 - 5.3e-28 98.0 0.1 8.4e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP88835.1 - 3.1e-16 59.8 0.1 4.4e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP88835.1 - 1.8e-06 27.7 0.0 2.7e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 GAP88835.1 - 0.00039 19.6 0.0 0.00049 19.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 GAP88835.1 - 0.00094 18.6 0.2 0.0031 16.9 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAP88835.1 - 0.00094 18.1 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 GAP88835.1 - 0.0011 19.0 0.1 0.0017 18.4 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 GAP88835.1 - 0.0081 15.0 0.1 0.028 13.3 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain HET PF06985.6 GAP88836.1 - 8.2e-27 94.0 0.0 1.4e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SERTA PF06031.8 GAP88836.1 - 0.0068 15.6 0.0 0.015 14.5 0.0 1.6 1 0 0 1 1 1 1 SERTA motif MbtH PF03621.8 GAP88836.1 - 0.21 11.0 1.4 7.4 6.0 0.0 3.0 3 0 0 3 3 3 0 MbtH-like protein Ank_2 PF12796.2 GAP88837.1 - 4.1e-113 369.9 21.8 2e-19 69.7 0.1 10.3 4 2 6 11 11 11 10 Ankyrin repeats (3 copies) Ank PF00023.25 GAP88837.1 - 4.5e-86 278.6 22.5 2.4e-07 30.2 0.5 17.6 17 0 0 17 17 17 14 Ankyrin repeat Ank_4 PF13637.1 GAP88837.1 - 1.6e-72 238.6 14.8 6.5e-09 36.0 0.0 13.5 7 3 8 15 15 15 14 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP88837.1 - 6.6e-66 211.6 11.5 8.6e-05 22.4 0.1 18.0 19 0 0 19 19 19 15 Ankyrin repeat Ank_5 PF13857.1 GAP88837.1 - 1.8e-61 202.7 23.1 1.2e-07 31.6 0.1 14.9 7 3 6 15 15 15 14 Ankyrin repeats (many copies) CorA PF01544.13 GAP88837.1 - 4.7e-07 29.1 1.2 9.8e-07 28.0 0.8 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2229 PF09989.4 GAP88837.1 - 0.42 10.0 1.8 1 8.7 0.4 2.1 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) AMP-binding PF00501.23 GAP88839.1 - 2.7e-65 220.4 0.0 4.5e-65 219.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 GAP88839.1 - 1.2e-12 47.8 0.0 2.5e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.19 GAP88839.1 - 7.7e-10 37.8 3.0 0.00012 21.3 0.0 4.6 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) AMP-binding_C PF13193.1 GAP88839.1 - 0.00017 22.4 3.7 0.033 15.1 0.0 3.0 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain DUF3439 PF11921.3 GAP88839.1 - 0.31 10.8 15.3 0.12 12.1 4.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Hexapep_2 PF14602.1 GAP88839.1 - 0.66 9.5 11.2 13 5.3 0.1 5.1 4 1 1 5 5 5 0 Hexapeptide repeat of succinyl-transferase LVIVD PF08309.6 GAP88841.1 - 0.00088 18.2 0.2 0.015 14.2 0.1 2.8 3 0 0 3 3 3 1 LVIVD repeat DUF3328 PF11807.3 GAP88842.1 - 2.8e-26 92.5 0.0 3.9e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Ribosomal_S19e PF01090.14 GAP88843.1 - 4.6e-58 194.6 0.3 5.3e-58 194.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Amino_oxidase PF01593.19 GAP88844.1 - 9.1e-61 206.2 2.4 1.5e-60 205.5 1.7 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAP88844.1 - 3.8e-07 30.0 0.1 9.4e-07 28.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAP88844.1 - 1.5e-05 25.1 0.2 9.8e-05 22.5 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 GAP88844.1 - 0.0038 17.3 0.1 0.0066 16.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.16 GAP88844.1 - 0.0063 16.0 0.1 0.22 11.1 0.1 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 GAP88844.1 - 0.0069 16.7 0.3 0.66 10.4 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 GAP88844.1 - 0.0085 15.9 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 ThiF family FAD_binding_3 PF01494.14 GAP88844.1 - 0.016 14.2 0.2 0.045 12.8 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 GAP88844.1 - 0.03 14.2 0.2 0.05 13.4 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAP88844.1 - 0.036 13.8 0.4 1.2 8.8 0.1 2.5 2 1 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.19 GAP88844.1 - 0.055 12.3 1.8 0.41 9.5 0.6 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase CorA PF01544.13 GAP88845.1 - 4e-27 94.9 8.2 1.3e-22 80.2 4.4 3.0 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Plasmodium_Vir PF05795.6 GAP88845.1 - 0.02 14.0 0.0 0.045 12.9 0.0 1.6 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Alk_phosphatase PF00245.15 GAP88846.1 - 2.3e-110 369.1 0.0 2.8e-110 368.9 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 GAP88846.1 - 0.00013 21.4 0.0 0.00028 20.3 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily LRR_4 PF12799.2 GAP88847.1 - 0.0022 17.6 6.7 5.7 6.6 0.8 5.1 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) F-box-like PF12937.2 GAP88847.1 - 0.058 13.1 0.7 0.27 10.9 0.1 2.3 2 0 0 2 2 2 0 F-box-like Rad9 PF04139.8 GAP88848.1 - 4.4e-65 219.2 0.0 5.3e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 Rad9 RCC1 PF00415.13 GAP88849.1 - 2.1e-28 98.2 16.5 3.8e-12 46.2 0.0 7.1 6 2 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAP88849.1 - 4.6e-21 73.8 21.6 3e-06 26.6 0.7 6.2 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat PapC_C PF13953.1 GAP88849.1 - 0.0075 15.8 0.0 0.73 9.5 0.0 2.6 2 0 0 2 2 2 1 PapC C-terminal domain RNA_helicase PF00910.17 GAP88849.1 - 0.041 14.0 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA helicase PDH PF02153.12 GAP88850.1 - 1.2e-14 53.8 0.0 1.7e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 GAP88850.1 - 1.8e-06 28.2 0.0 4.3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 GAP88850.1 - 1e-05 25.4 0.0 2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 GAP88850.1 - 0.00025 20.5 0.0 0.00045 19.6 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 GAP88850.1 - 0.00093 18.3 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 GAP88850.1 - 0.017 14.7 0.0 0.047 13.3 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 GAP88850.1 - 0.039 13.9 0.0 0.076 13.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_2 PF00890.19 GAP88851.1 - 1.4e-93 314.0 5.4 1.6e-93 313.8 3.7 1.0 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 GAP88851.1 - 6.4e-08 32.0 0.2 1.2e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 GAP88851.1 - 1.7e-07 31.3 0.0 8e-06 25.8 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP88851.1 - 3.9e-07 30.0 0.8 1.6e-06 28.0 0.6 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAP88851.1 - 1.8e-06 27.0 5.4 2.6e-05 23.3 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 GAP88851.1 - 3.1e-05 23.1 1.1 0.00061 18.9 0.2 2.6 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.17 GAP88851.1 - 0.00013 21.0 0.4 0.00058 18.8 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 GAP88851.1 - 0.0002 21.5 0.3 0.00048 20.2 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAP88851.1 - 0.0003 20.0 1.2 0.00051 19.2 0.8 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAP88851.1 - 0.0034 15.9 0.2 0.0034 15.9 0.2 2.7 3 0 0 3 3 3 1 HI0933-like protein Lycopene_cycl PF05834.7 GAP88851.1 - 0.011 14.6 0.4 0.017 14.0 0.3 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAP88851.1 - 0.019 14.7 0.7 0.07 12.8 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 GAP88851.1 - 0.042 13.2 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 GAP88851.1 - 0.12 12.7 1.1 0.45 10.9 0.4 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 GAP88852.1 - 2.9e-41 140.5 0.0 4.9e-26 90.9 0.0 2.1 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gp_dh_N PF00044.19 GAP88852.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.5 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAP88852.1 - 0.056 12.9 0.0 0.068 12.6 0.0 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3HCDH_N PF02737.13 GAP88852.1 - 0.058 13.0 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DSS1_SEM1 PF05160.8 GAP88852.1 - 0.13 12.0 0.4 0.27 11.0 0.3 1.5 1 0 0 1 1 1 0 DSS1/SEM1 family NAD_binding_10 PF13460.1 GAP88852.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.6 2 0 0 2 2 2 0 NADH(P)-binding F420_oxidored PF03807.12 GAP88852.1 - 0.14 12.6 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent XdhC_C PF13478.1 GAP88852.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain DUF3328 PF11807.3 GAP88853.1 - 1.9e-18 66.9 3.5 2.4e-18 66.6 2.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 GAP88854.1 - 2.5e-09 37.1 0.0 3.4e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Peptidase_M14 PF00246.19 GAP88856.1 - 1.7e-68 231.2 0.3 2.5e-68 230.6 0.2 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Ricin_B_lectin PF00652.17 GAP88857.1 - 1.1e-15 57.7 0.0 1.3e-05 25.1 0.0 4.0 2 2 1 3 3 3 3 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.9 GAP88857.1 - 0.1 11.9 0.1 0.83 9.0 0.0 2.5 2 1 1 3 3 3 0 Cytolethal distending toxin A/C family DUF3157 PF11355.3 GAP88857.1 - 7.2 5.8 7.8 12 5.0 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) NmrA PF05368.8 GAP88858.1 - 2.8e-34 118.3 0.0 3.4e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAP88858.1 - 1.9e-10 41.0 0.3 2.6e-10 40.6 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAP88858.1 - 7.4e-05 22.2 0.0 0.00015 21.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAP88858.1 - 0.00075 19.4 0.4 0.0013 18.6 0.3 1.5 1 1 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 GAP88858.1 - 0.0038 15.9 0.1 0.0056 15.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 GAP88858.1 - 0.012 15.2 0.1 0.021 14.4 0.1 1.4 1 0 0 1 1 1 0 KR domain DapB_N PF01113.15 GAP88858.1 - 0.077 12.9 0.1 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 GAP88858.1 - 0.082 11.8 0.1 0.27 10.1 0.0 1.8 2 0 0 2 2 2 0 Male sterility protein DUF1772 PF08592.6 GAP88859.1 - 1.2e-16 60.7 0.0 1.3e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) p450 PF00067.17 GAP88860.1 - 3.3e-45 154.4 0.0 5.8e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 Dicty_REP PF05086.7 GAP88860.1 - 2 6.0 7.4 2.8 5.5 5.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FAD_binding_2 PF00890.19 GAP88861.1 - 1.8e-07 30.3 0.0 2e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 GAP88861.1 - 2.8e-05 23.3 0.2 3.4e-05 23.0 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAP88861.1 - 3e-05 23.9 0.0 4.3e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAP88861.1 - 4.4e-05 23.4 0.0 4.5e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAP88861.1 - 0.00033 19.6 0.0 0.00037 19.4 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 GAP88861.1 - 0.00035 19.1 0.1 0.00044 18.8 0.1 1.1 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 GAP88861.1 - 0.00081 18.5 0.0 0.00096 18.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 GAP88861.1 - 0.00086 18.3 0.0 0.0009 18.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 GAP88861.1 - 0.0013 18.3 0.0 0.0013 18.3 0.0 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 GAP88861.1 - 0.0031 16.6 0.0 0.0036 16.4 0.0 1.1 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 GAP88861.1 - 0.013 15.8 0.0 0.016 15.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAP88861.1 - 0.035 13.0 0.0 0.036 12.9 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.13 GAP88861.1 - 0.077 12.6 0.0 0.081 12.5 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 GAP88861.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Strep_67kDa_ant PF06100.6 GAP88861.1 - 0.12 10.7 0.0 0.12 10.7 0.0 1.0 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family FAD_binding_3 PF01494.14 GAP88862.1 - 7.6e-13 48.2 0.7 2.6e-05 23.4 0.3 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAP88862.1 - 0.0023 16.8 0.7 0.0084 15.0 0.5 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pro-kuma_activ PF09286.6 GAP88863.1 - 2.7e-37 127.9 0.0 4.7e-37 127.2 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 GAP88863.1 - 1.1e-09 37.8 1.0 2.6e-09 36.6 0.7 1.6 1 0 0 1 1 1 1 Subtilase family DUF2264 PF10022.4 GAP88863.1 - 0.076 11.6 0.0 0.14 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) Arrestin_C PF02752.17 GAP88864.1 - 7.9e-19 68.1 0.0 3.3e-18 66.1 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 GAP88864.1 - 6.3e-08 32.5 1.8 0.0083 15.9 0.0 3.2 3 1 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Glyco_hydro_10 PF00331.15 GAP88865.1 - 1e-24 87.1 0.0 1.1e-24 87.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_10 PF00331.15 GAP88866.1 - 9.6e-24 83.9 0.0 1.1e-23 83.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 GAP88866.1 - 2e-12 46.5 17.5 2e-12 46.5 12.1 2.5 3 0 0 3 3 3 1 Fungal cellulose binding domain p450 PF00067.17 GAP88867.1 - 3.9e-49 167.4 0.0 5.2e-49 167.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAR1 PF03101.10 GAP88868.1 - 2.4e-05 24.7 0.2 4.9e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain Snapin_Pallidin PF14712.1 GAP88868.1 - 0.0013 19.0 0.0 0.0021 18.3 0.0 1.3 1 0 0 1 1 1 1 Snapin/Pallidin WASH_WAHD PF11945.3 GAP88868.1 - 0.0014 18.0 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 WAHD domain of WASH complex AFT PF08731.6 GAP88868.1 - 0.0067 16.6 0.2 0.012 15.8 0.2 1.4 1 0 0 1 1 1 1 Transcription factor AFT Matrilin_ccoil PF10393.4 GAP88868.1 - 0.0072 15.6 0.3 0.15 11.4 0.1 2.3 2 0 0 2 2 2 1 Trimeric coiled-coil oligomerisation domain of matrilin DUF1664 PF07889.7 GAP88868.1 - 0.027 14.2 0.1 0.044 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) COG2 PF06148.6 GAP88868.1 - 0.04 13.7 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Sugarporin_N PF11471.3 GAP88868.1 - 0.21 11.2 1.1 0.55 9.9 0.7 1.7 1 1 0 1 1 1 0 Maltoporin periplasmic N-terminal extension GAT PF03127.9 GAP88869.1 - 0.047 13.6 0.3 0.097 12.6 0.2 1.6 1 1 0 1 1 1 0 GAT domain DUF362 PF04015.7 GAP88869.1 - 0.062 12.7 0.0 0.078 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF362) eIF-3c_N PF05470.7 GAP88870.1 - 1.2e-176 588.3 22.2 1.2e-176 588.3 15.4 3.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 GAP88870.1 - 6.1e-14 52.2 0.1 2.7e-13 50.1 0.1 2.2 1 0 0 1 1 1 1 PCI domain Hemerythrin PF01814.18 GAP88871.1 - 1.3e-12 48.0 5.8 3e-08 33.9 1.3 2.2 2 0 0 2 2 2 2 Hemerythrin HHE cation binding domain Myc_N PF01056.13 GAP88871.1 - 0.0024 17.1 0.7 0.0029 16.8 0.5 1.2 1 0 0 1 1 1 1 Myc amino-terminal region YqfQ PF14181.1 GAP88871.1 - 1.7 8.7 6.3 2.5 8.1 4.4 1.2 1 0 0 1 1 1 0 YqfQ-like protein SnoaL_4 PF13577.1 GAP88872.1 - 1.6e-06 28.0 0.0 3.3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like domain Cellulase PF00150.13 GAP88873.1 - 2.2e-16 59.8 0.1 3e-16 59.4 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.11 GAP88876.1 - 5.5e-18 64.8 51.6 2.7e-10 39.4 13.1 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP88876.1 - 0.00021 19.9 8.5 0.00021 19.9 5.9 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter Acetyltransf_1 PF00583.19 GAP88877.1 - 6.1e-07 29.3 0.3 1.1e-06 28.5 0.2 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAP88877.1 - 0.00064 19.8 0.0 0.0016 18.5 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAP88877.1 - 0.014 15.4 0.0 0.036 14.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DIOX_N PF14226.1 GAP88878.1 - 2.6e-12 47.3 0.0 6.7e-12 45.9 0.0 1.8 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAP88878.1 - 3.7e-06 27.1 0.0 1.3e-05 25.3 0.0 2.0 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.2 GAP88879.1 - 7.2e-43 144.8 0.0 2.4e-19 69.4 0.1 3.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAP88879.1 - 1.2e-26 91.1 5.5 7.9e-08 31.7 0.0 5.2 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 GAP88879.1 - 3.5e-18 65.5 2.1 6.5e-10 39.2 0.2 3.4 2 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP88879.1 - 6e-16 56.9 2.2 0.0013 18.7 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 GAP88879.1 - 4.8e-12 45.7 7.2 3.5e-05 23.9 0.2 4.9 2 1 3 5 5 5 5 Ankyrin repeats (many copies) HET PF06985.6 GAP88881.1 - 3.4e-20 72.6 5.8 3.2e-17 62.9 0.3 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) PTCB-BRCT PF12738.2 GAP88882.1 - 1.4e-41 140.1 0.0 3.1e-21 74.9 0.0 3.4 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.21 GAP88882.1 - 2.9e-35 120.2 0.0 4.9e-13 49.0 0.0 4.5 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain DapB_N PF01113.15 GAP88882.1 - 0.13 12.1 0.1 1.1 9.2 0.0 2.4 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus PQQ_2 PF13360.1 GAP88884.1 - 0.0014 18.1 0.2 0.022 14.2 0.0 2.3 1 1 0 2 2 2 1 PQQ-like domain AAA PF00004.24 GAP88885.1 - 2.9e-08 33.9 0.3 1.8e-07 31.3 0.2 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 GAP88885.1 - 6.4e-05 21.8 0.0 0.0024 16.6 0.0 2.8 2 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 GAP88885.1 - 7.5e-05 22.7 0.0 0.00028 20.9 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain AAA_17 PF13207.1 GAP88885.1 - 0.00045 21.0 0.0 0.0016 19.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 GAP88885.1 - 0.0047 17.0 0.0 0.022 14.8 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 GAP88885.1 - 0.012 15.2 0.0 0.034 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 GAP88885.1 - 0.016 15.0 0.1 0.23 11.3 0.0 2.8 3 1 0 3 3 3 0 AAA domain TIP49 PF06068.8 GAP88885.1 - 0.022 13.4 0.0 0.035 12.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus ABC_tran PF00005.22 GAP88885.1 - 0.06 13.6 0.0 0.37 11.0 0.0 2.3 2 1 0 2 2 2 0 ABC transporter AAA_19 PF13245.1 GAP88885.1 - 0.061 13.0 0.1 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain IF2_N PF04760.10 GAP88885.1 - 0.068 12.8 0.2 2 8.1 0.0 2.4 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region RuvB_N PF05496.7 GAP88885.1 - 0.094 11.7 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 GAP88885.1 - 0.17 11.5 0.0 6 6.5 0.0 2.4 1 1 0 1 1 1 0 NTPase RNA_helicase PF00910.17 GAP88885.1 - 0.18 12.0 0.0 0.81 9.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Pec_lyase_C PF00544.14 GAP88886.1 - 3.4e-27 95.2 0.0 9.2e-27 93.8 0.0 1.6 2 0 0 2 2 2 1 Pectate lyase His_Phos_2 PF00328.17 GAP88887.1 - 1.8e-26 93.3 0.0 2.3e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 GAP88887.1 - 0.03 14.4 0.0 0.044 13.8 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) SIR2 PF02146.12 GAP88888.1 - 5.8e-34 117.3 0.0 1.4e-33 116.0 0.0 1.7 1 1 0 1 1 1 1 Sir2 family Glyco_transf_28 PF03033.15 GAP88888.1 - 0.017 14.8 0.3 0.66 9.7 0.2 2.3 2 0 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain PDR_CDR PF06422.7 GAP88889.1 - 0.024 14.3 0.4 0.081 12.5 0.0 2.1 3 0 0 3 3 3 0 CDR ABC transporter Fungal_trans PF04082.13 GAP88891.1 - 8.3e-07 28.1 0.0 1.3e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NMO PF03060.10 GAP88893.1 - 1.8e-42 145.6 5.3 3.7e-42 144.6 3.7 1.5 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 GAP88893.1 - 9.3e-08 31.2 6.2 1.5e-07 30.6 4.3 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 GAP88893.1 - 1.2e-05 24.4 4.0 0.0096 14.8 3.0 2.3 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 GAP88893.1 - 3.9e-05 22.7 2.5 5.9e-05 22.1 1.7 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase CAP_N PF01213.14 GAP88893.1 - 0.013 14.7 5.1 0.021 14.1 3.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 GAP88893.1 - 0.12 11.6 7.6 0.23 10.8 5.2 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Cyclin PF08613.6 GAP88894.1 - 4.4e-16 59.6 0.0 7.2e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 GAP88894.1 - 0.0025 17.3 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Acetyltransf_3 PF13302.1 GAP88896.1 - 2.4e-28 99.0 0.0 3.1e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3433 PF11915.3 GAP88897.1 - 7.8e-14 51.6 6.9 1.3e-06 28.4 0.5 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) MFS_1 PF07690.11 GAP88899.1 - 3.7e-33 114.6 52.8 1.1e-32 113.1 27.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3328 PF11807.3 GAP88900.1 - 2.8e-32 112.1 0.1 3.6e-32 111.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) WBP-1 PF11669.3 GAP88901.1 - 0.0095 15.9 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 WW domain-binding protein 1 EF-hand_1 PF00036.27 GAP88902.1 - 1.2e-22 77.4 2.4 3.2e-09 35.4 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 GAP88902.1 - 2.2e-22 78.9 0.0 2.6e-12 46.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 GAP88902.1 - 9.8e-22 76.3 0.9 2.6e-13 49.3 0.0 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 GAP88902.1 - 6.6e-15 53.6 0.0 0.00091 18.9 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 GAP88902.1 - 8.2e-12 43.9 3.5 6.6e-05 22.0 0.1 3.7 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.2 GAP88902.1 - 3.3e-07 30.0 0.0 0.00019 21.1 0.0 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 GAP88902.1 - 1.9e-06 27.7 0.0 0.0011 18.8 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.8 GAP88902.1 - 0.00023 20.7 0.0 0.55 9.8 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.4 GAP88902.1 - 0.028 14.4 0.0 7.9 6.5 0.0 2.5 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Aldo_ket_red PF00248.16 GAP88903.1 - 1.4e-45 155.3 0.0 1.9e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family CYSTM PF12734.2 GAP88903.1 - 0.25 11.4 1.5 0.68 10.0 1.1 1.7 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance eRF1_1 PF03463.10 GAP88904.1 - 7.6e-40 135.5 0.0 1.6e-39 134.4 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 GAP88904.1 - 1.4e-22 80.4 0.0 2.1e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 GAP88904.1 - 7.5e-19 68.0 0.0 1.5e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 WD40 PF00400.27 GAP88905.1 - 1.3e-33 113.6 11.8 6.2e-10 38.5 0.0 7.9 8 0 0 8 8 8 4 WD domain, G-beta repeat B_lectin PF01453.19 GAP88905.1 - 0.055 13.3 0.0 0.25 11.2 0.0 2.0 2 0 0 2 2 2 0 D-mannose binding lectin Ribosomal_S27 PF01599.14 GAP88905.1 - 1.8 8.4 4.8 4.7 7.1 3.3 1.7 1 0 0 1 1 1 0 Ribosomal protein S27a WD40 PF00400.27 GAP88906.1 - 1.3e-24 85.0 8.9 9.8e-10 37.9 0.1 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 GAP88906.1 - 4e-16 58.6 0.0 8.8e-16 57.5 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex K_channel_TID PF07941.6 GAP88906.1 - 0.015 15.4 2.1 0.041 14.0 1.4 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain ILVD_EDD PF00920.16 GAP88907.1 - 9.9e-187 621.4 1.5 1.1e-186 621.3 1.1 1.0 1 0 0 1 1 1 1 Dehydratase family Lactonase PF10282.4 GAP88908.1 - 2e-41 142.2 0.0 3.2e-24 85.6 0.0 2.0 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller Glyco_hydro_16 PF00722.16 GAP88909.1 - 2.4e-42 144.3 6.3 2.4e-42 144.3 4.4 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 GAP88909.1 - 0.087 12.8 13.2 0.22 11.5 9.1 1.6 1 0 0 1 1 1 0 Chitin recognition protein NUDIX PF00293.23 GAP88910.1 - 0.015 14.9 0.2 0.04 13.5 0.1 1.6 1 0 0 1 1 1 0 NUDIX domain Myb_DNA-binding PF00249.26 GAP88911.1 - 1.4e-13 50.6 2.0 6.9e-07 29.2 0.4 2.9 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAP88911.1 - 3.5e-12 46.2 0.8 1.7e-05 24.8 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Macoilin PF09726.4 GAP88911.1 - 7.1 4.7 8.5 7 4.7 5.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Ribosomal_L18e PF00828.14 GAP88912.1 - 2.1e-16 60.4 0.0 2.3e-16 60.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 OHCU_decarbox PF09349.5 GAP88915.1 - 1.7e-37 129.1 0.0 9.7e-37 126.7 0.0 1.8 1 1 0 1 1 1 1 OHCU decarboxylase Prp19 PF08606.6 GAP88916.1 - 1.7e-31 107.7 2.2 2.2e-31 107.4 0.9 1.7 2 0 0 2 2 2 1 Prp19/Pso4-like WD40 PF00400.27 GAP88916.1 - 4e-09 36.0 0.2 0.011 15.5 0.0 4.7 7 0 0 7 7 7 2 WD domain, G-beta repeat eIF2A PF08662.6 GAP88916.1 - 0.0043 16.7 0.2 1.6 8.3 0.0 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A VID27 PF08553.5 GAP88916.1 - 0.01 14.1 0.0 0.017 13.4 0.0 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein zf-Nse PF11789.3 GAP88916.1 - 0.014 14.9 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 GAP88916.1 - 0.027 14.4 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 U-box domain CDC45 PF02724.9 GAP88917.1 - 0.00023 19.3 8.2 0.00023 19.3 5.7 2.2 2 0 0 2 2 2 1 CDC45-like protein Spore_coat_CotO PF14153.1 GAP88917.1 - 0.0065 15.9 0.7 0.0065 15.9 0.5 2.4 2 0 0 2 2 2 1 Spore coat protein CotO zf-RING_5 PF14634.1 GAP88917.1 - 0.0072 16.0 4.2 0.017 14.8 2.9 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAP88917.1 - 0.014 15.3 0.7 0.014 15.3 0.5 1.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SAPS PF04499.10 GAP88917.1 - 0.44 9.1 6.9 0.19 10.3 0.5 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein zf-C3HC4 PF00097.20 GAP88917.1 - 0.91 9.2 3.4 2.1 8.0 2.3 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) OPT PF03169.10 GAP88919.1 - 5e-96 322.5 43.2 5.7e-96 322.3 29.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4449 PF14613.1 GAP88921.1 - 2.8e-66 222.4 2.5 2.8e-66 222.4 1.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) YlqD PF11068.3 GAP88921.1 - 0.0083 16.1 2.1 0.0083 16.1 1.5 3.0 3 0 0 3 3 3 1 YlqD protein HAD_2 PF13419.1 GAP88922.1 - 3.7e-25 89.1 0.0 6.9e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Prenyltrans_2 PF13249.1 GAP88922.1 - 0.0031 17.9 0.0 2.6 8.4 0.0 2.4 2 0 0 2 2 2 2 Prenyltransferase-like Hydrolase_like PF13242.1 GAP88922.1 - 0.0078 15.8 0.0 0.023 14.3 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 GAP88922.1 - 0.02 15.3 0.0 0.84 10.0 0.0 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase EB1 PF03271.12 GAP88923.1 - 1.4e-17 63.4 1.7 2.6e-17 62.5 1.2 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 GAP88923.1 - 5.1e-06 26.4 1.1 8.2e-06 25.8 0.8 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF2183 PF09949.4 GAP88924.1 - 3.5e-31 107.1 0.0 7.4e-31 106.0 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.8 GAP88924.1 - 0.00018 21.0 0.0 0.00031 20.3 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Poxvirus_B22R_C PF13168.1 GAP88924.1 - 0.28 10.4 0.0 0.47 9.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal DEAD PF00270.24 GAP88925.1 - 3.2e-44 150.3 0.0 1e-43 148.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP88925.1 - 1.3e-24 85.8 0.0 2.8e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 GAP88925.1 - 2.6e-07 29.3 0.8 4.5e-06 25.3 0.0 2.6 1 1 2 3 3 3 1 Protein of unknown function (DUF1253) ResIII PF04851.10 GAP88925.1 - 0.089 12.6 0.0 0.62 9.8 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Y1_Tnp PF01797.11 GAP88926.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Transposase IS200 like p450 PF00067.17 GAP88928.1 - 8.8e-65 219.0 0.0 1.1e-64 218.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 GAP88930.1 - 4.9e-22 77.8 3.4 7.6e-22 77.2 2.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAP88930.1 - 2.1e-15 57.7 1.3 4e-15 56.8 0.9 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP88930.1 - 3.4e-10 39.6 0.0 3.9e-09 36.2 0.0 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ank PF00023.25 GAP88931.1 - 5.6e-80 259.4 12.2 1.2e-09 37.5 0.0 13.6 13 0 0 13 13 13 13 Ankyrin repeat Ank_2 PF12796.2 GAP88931.1 - 4.6e-79 260.8 13.9 2e-15 56.9 0.0 7.2 1 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAP88931.1 - 3.9e-62 205.6 26.0 1.7e-10 41.1 0.0 10.3 4 3 8 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP88931.1 - 2.9e-61 197.2 12.7 1.8e-05 24.4 0.0 13.6 13 0 0 13 13 13 12 Ankyrin repeat Ank_5 PF13857.1 GAP88931.1 - 3e-49 163.9 19.7 5e-10 39.2 0.3 10.1 3 2 7 11 11 11 11 Ankyrin repeats (many copies) p450 PF00067.17 GAP88932.1 - 5.5e-29 100.9 0.0 2e-27 95.8 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 FAD_binding_4 PF01565.18 GAP88933.1 - 2.2e-25 88.7 0.5 3.7e-25 88.0 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP88933.1 - 5.9e-05 22.8 0.1 0.00013 21.8 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Prion_bPrPp PF11587.3 GAP88933.1 - 0.36 10.5 2.4 0.8 9.4 1.6 1.6 1 0 0 1 1 1 0 Major prion protein bPrPp - N terminal p450 PF00067.17 GAP88934.1 - 6.3e-41 140.3 0.0 3.2e-38 131.4 0.0 2.3 2 0 0 2 2 2 2 Cytochrome P450 adh_short PF00106.20 GAP88935.1 - 7.6e-13 48.7 0.0 5.9e-12 45.8 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAP88935.1 - 2.6e-05 23.9 0.0 4.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAP88935.1 - 0.00053 19.4 0.0 0.0013 18.2 0.0 1.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAP88935.1 - 0.0042 17.1 0.0 0.013 15.4 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding DUF2611 PF11022.3 GAP88937.1 - 1 9.5 4.3 4.7 7.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2611) DUF1664 PF07889.7 GAP88938.1 - 0.036 13.8 2.0 0.066 13.0 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF760 PF05542.6 GAP88938.1 - 0.05 13.7 0.7 27 5.0 0.2 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF760) BLOC1_2 PF10046.4 GAP88938.1 - 0.13 12.3 1.9 4.9 7.3 0.0 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GCN5L1 PF06320.8 GAP88938.1 - 3.4 7.5 7.6 0.77 9.5 1.1 3.0 3 1 1 4 4 4 0 GCN5-like protein 1 (GCN5L1) Citrate_ly_lig PF08218.6 GAP88939.1 - 0.0011 18.4 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Citrate lyase ligase C-terminal domain DUF3220 PF11516.3 GAP88939.1 - 0.046 13.6 0.1 0.08 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) APC10 PF03256.11 GAP88940.1 - 5.3e-50 169.7 0.0 8e-50 169.1 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Peptidase_M1 PF01433.15 GAP88941.1 - 4.1e-134 447.5 0.7 6.1e-134 446.9 0.5 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 GAP88941.1 - 7.4e-71 239.0 0.1 1.4e-70 238.1 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 GAP88941.1 - 1.6e-17 63.7 1.6 1.6e-17 63.7 1.1 2.5 1 1 1 2 2 2 1 Peptidase MA superfamily DUF2808 PF10989.3 GAP88941.1 - 0.017 14.7 0.1 0.049 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) DUF45 PF01863.12 GAP88941.1 - 0.15 11.8 2.3 0.3 10.8 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function DUF45 SurA_N_2 PF13623.1 GAP88942.1 - 0.11 12.5 2.6 0.18 11.7 1.8 1.4 1 0 0 1 1 1 0 SurA N-terminal domain DUF3963 PF13124.1 GAP88942.1 - 0.19 11.5 0.3 0.32 10.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) CBFD_NFYB_HMF PF00808.18 GAP88943.1 - 0.00011 22.1 0.6 0.00013 21.9 0.4 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAFII28 PF04719.9 GAP88943.1 - 0.045 13.5 0.4 0.058 13.1 0.3 1.2 1 0 0 1 1 1 0 hTAFII28-like protein conserved region DOMON PF03351.12 GAP88944.1 - 0.0013 18.6 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 DOMON domain MPLKIP PF15502.1 GAP88945.1 - 1.3 9.7 11.4 2.2 8.9 7.9 1.3 1 0 0 1 1 1 0 M-phase-specific PLK1-interacting protein Ank_2 PF12796.2 GAP88947.1 - 4.3e-75 248.1 14.4 2.2e-18 66.3 0.1 5.1 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAP88947.1 - 1.1e-42 143.6 12.1 3.5e-10 40.1 0.1 7.4 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.25 GAP88947.1 - 3.1e-35 118.2 11.9 5.2e-07 29.1 0.0 8.4 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 GAP88947.1 - 1.8e-28 97.8 15.0 5.5e-07 29.6 0.1 5.5 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP88947.1 - 1.9e-24 83.2 0.8 0.00014 21.7 0.0 9.5 9 0 0 9 9 9 5 Ankyrin repeat NACHT PF05729.7 GAP88947.1 - 5.6e-07 29.3 0.0 2.2e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 GAP88947.1 - 0.004 17.1 1.4 0.027 14.4 0.1 2.9 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 GAP88947.1 - 0.02 15.0 0.0 0.083 13.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 GAP88947.1 - 0.09 12.9 0.1 0.37 10.9 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MGC-24 PF05283.6 GAP88947.1 - 0.32 10.7 2.9 0.68 9.6 2.0 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) RVT_1 PF00078.22 GAP88949.1 - 0.0041 16.4 0.0 0.0084 15.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SWIM PF04434.12 GAP88950.1 - 0.00073 18.9 0.9 0.24 10.9 0.0 2.3 2 0 0 2 2 2 2 SWIM zinc finger MitMem_reg PF13012.1 GAP88951.1 - 2.3e-37 127.6 0.3 5.7e-37 126.3 0.1 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 GAP88951.1 - 5.9e-29 100.1 0.6 1.8e-28 98.5 0.0 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF1682 PF07946.9 GAP88951.1 - 0.02 13.7 9.6 0.031 13.1 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) OAD_gamma PF04277.8 GAP88951.1 - 0.051 13.9 1.7 0.12 12.7 1.2 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF3987 PF13148.1 GAP88951.1 - 0.87 8.0 10.4 1.7 7.1 7.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ADK PF00406.17 GAP88952.1 - 3.4e-59 199.0 0.0 4.6e-59 198.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 GAP88952.1 - 1.6e-14 53.2 0.0 9.3e-14 50.8 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.1 GAP88952.1 - 2.7e-06 27.3 0.0 1.4e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAP88952.1 - 3.1e-06 28.0 0.2 7.4e-06 26.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAP88952.1 - 0.00015 22.0 0.2 0.0058 16.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 GAP88952.1 - 0.0028 16.7 0.0 0.0051 15.9 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin DivIVA PF05103.8 GAP88952.1 - 0.05 13.6 0.0 1 9.4 0.0 2.1 2 0 0 2 2 2 0 DivIVA protein DUF1664 PF07889.7 GAP88952.1 - 0.16 11.7 0.7 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) HALZ PF02183.13 GAP88953.1 - 0.0007 19.2 2.7 0.0007 19.2 1.8 10.1 6 4 5 11 11 11 3 Homeobox associated leucine zipper Atg14 PF10186.4 GAP88953.1 - 0.0034 16.3 70.4 0.031 13.2 0.6 4.4 2 2 2 4 4 4 4 UV radiation resistance protein and autophagy-related subunit 14 TPR_MLP1_2 PF07926.7 GAP88953.1 - 0.0067 16.1 2.2 0.0067 16.1 1.6 5.9 4 2 0 4 4 4 2 TPR/MLP1/MLP2-like protein DUF904 PF06005.7 GAP88953.1 - 0.014 15.6 2.9 0.014 15.6 2.0 8.4 5 1 1 6 6 6 0 Protein of unknown function (DUF904) CENP-F_leu_zip PF10473.4 GAP88953.1 - 5.9 6.7 82.5 0.022 14.6 10.8 5.9 2 1 4 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ank_2 PF12796.2 GAP88954.1 - 1.2e-124 406.9 25.8 4.9e-16 58.8 0.0 14.6 4 3 9 14 14 14 14 Ankyrin repeats (3 copies) Ank PF00023.25 GAP88954.1 - 6.8e-85 274.9 65.7 3.3e-05 23.4 0.1 28.4 29 1 1 30 30 30 20 Ankyrin repeat Ank_4 PF13637.1 GAP88954.1 - 2.4e-81 266.8 34.0 3.1e-09 37.0 0.1 18.2 14 3 8 22 22 22 16 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP88954.1 - 5.6e-70 229.7 49.3 2e-06 27.8 0.0 22.6 10 4 14 25 25 25 18 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP88954.1 - 2.2e-59 191.4 38.3 0.01 16.0 0.0 27.7 31 0 0 31 31 31 14 Ankyrin repeat SPRY PF00622.23 GAP88954.1 - 8.1e-16 58.2 0.1 1.6e-15 57.3 0.1 1.5 1 0 0 1 1 1 1 SPRY domain Peptidase_S8 PF00082.17 GAP88955.1 - 1.8e-22 79.8 0.2 3.9e-22 78.7 0.1 1.6 1 0 0 1 1 1 1 Subtilase family Ank PF00023.25 GAP88955.1 - 0.0035 17.0 0.0 0.07 12.9 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 GAP88955.1 - 0.013 15.7 0.0 0.043 14.1 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAP88955.1 - 0.098 12.9 0.0 23 5.3 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Prothymosin PF03247.9 GAP88955.1 - 0.24 11.5 18.4 0.58 10.3 12.8 1.6 1 0 0 1 1 1 0 Prothymosin/parathymosin family Inhibitor_I9 PF05922.11 GAP88956.1 - 0.0018 18.7 0.0 0.0025 18.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF3186 PF11382.3 GAP88956.1 - 0.0026 16.9 0.0 0.0031 16.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3186) Glyco_hydro_71 PF03659.9 GAP88957.1 - 1.7e-117 392.2 0.9 1.9e-117 392.0 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.1 GAP88957.1 - 0.019 14.7 0.0 0.17 11.6 0.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) Abhydrolase_6 PF12697.2 GAP88959.1 - 2e-16 60.6 0.0 2.8e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP88959.1 - 0.00066 19.3 0.0 0.0021 17.6 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP88959.1 - 0.0048 16.6 0.0 0.0062 16.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrophobin_2 PF06766.6 GAP88960.1 - 1.4e-26 91.9 9.4 1.7e-26 91.6 6.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin MFS_1 PF07690.11 GAP88961.1 - 2e-32 112.3 28.6 2e-32 112.3 19.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily CcmD PF04995.9 GAP88961.1 - 3.6 7.4 7.1 0.46 10.2 0.5 2.8 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Ribosom_S12_S23 PF00164.20 GAP88963.1 - 1.6e-41 140.5 0.4 1.8e-41 140.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 UbiA PF01040.13 GAP88964.1 - 2.6e-34 118.6 19.0 3.3e-34 118.2 13.2 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family JmjC PF02373.17 GAP88965.1 - 8e-10 38.9 0.2 8e-10 38.9 0.1 2.5 3 1 0 3 3 3 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 GAP88965.1 - 1.3e-05 25.2 8.6 1.3e-05 25.2 5.9 2.7 3 0 0 3 3 3 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 GAP88965.1 - 0.013 14.9 0.0 0.03 13.8 0.0 1.6 1 0 0 1 1 1 0 Cupin domain Bac_transf PF02397.11 GAP88966.1 - 0.039 13.0 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial sugar transferase DUF1689 PF07954.6 GAP88967.1 - 0.0089 15.8 0.0 0.022 14.6 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1689) HATPase_c_3 PF13589.1 GAP88968.1 - 0.00036 20.1 0.1 0.00079 19.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3883 PF13020.1 GAP88968.1 - 0.005 16.5 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) Ank_2 PF12796.2 GAP88969.1 - 1.3e-26 92.6 11.4 6.6e-12 45.6 0.4 3.9 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAP88969.1 - 5e-26 89.1 8.7 2e-05 24.1 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.1 GAP88969.1 - 3.3e-19 67.0 9.1 0.0063 16.6 0.0 7.5 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 GAP88969.1 - 6.4e-19 67.5 17.3 7.3e-08 32.4 0.2 6.7 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAP88969.1 - 1.7e-18 66.6 9.9 4.9e-06 26.9 0.3 5.0 4 1 0 4 4 4 3 Ankyrin repeats (many copies) CorA PF01544.13 GAP88969.1 - 1.9e-05 23.8 0.1 0.17 10.8 0.0 2.7 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Bromodomain PF00439.20 GAP88971.1 - 1.3e-13 50.6 0.0 3.6e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Bromodomain CENP-Q PF13094.1 GAP88972.1 - 0.00078 19.5 1.4 0.00092 19.2 1.0 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit SlyX PF04102.7 GAP88972.1 - 0.0098 16.2 2.3 0.0098 16.2 1.6 1.7 1 1 1 2 2 2 1 SlyX DUF869 PF05911.6 GAP88972.1 - 0.013 13.7 0.7 0.012 13.8 0.5 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) DUF16 PF01519.11 GAP88972.1 - 0.013 15.6 0.2 0.019 15.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 IFT57 PF10498.4 GAP88972.1 - 0.021 13.5 1.2 0.027 13.2 0.8 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Herpes_UL6 PF01763.11 GAP88972.1 - 0.023 12.9 0.2 0.027 12.6 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Allexi_40kDa PF05549.6 GAP88972.1 - 0.027 13.7 1.4 0.032 13.5 1.0 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein CASP_C PF08172.7 GAP88972.1 - 0.032 13.2 1.0 0.039 12.9 0.7 1.1 1 0 0 1 1 1 0 CASP C terminal DUF4407 PF14362.1 GAP88972.1 - 0.036 13.0 1.7 0.038 12.9 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TBPIP PF07106.8 GAP88972.1 - 0.039 13.5 0.7 0.051 13.1 0.5 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HCMV_UL139 PF12507.3 GAP88972.1 - 0.045 13.9 0.1 0.059 13.5 0.1 1.2 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein DUF3763 PF12592.3 GAP88972.1 - 0.049 13.2 0.6 2.8 7.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3763) Spc24 PF08286.6 GAP88972.1 - 0.06 13.0 1.8 0.092 12.4 1.3 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Prefoldin_2 PF01920.15 GAP88972.1 - 0.078 12.7 2.3 0.14 11.9 1.6 1.4 1 0 0 1 1 1 0 Prefoldin subunit V-SNARE PF05008.10 GAP88972.1 - 0.16 12.1 3.5 0.13 12.4 1.5 1.5 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Med9 PF07544.8 GAP88972.1 - 0.16 11.6 2.0 0.45 10.2 0.5 2.1 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Herpes_UL25 PF01499.11 GAP88972.1 - 0.19 10.0 2.6 0.21 9.8 1.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF972 PF06156.8 GAP88972.1 - 0.2 12.0 1.3 0.28 11.5 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) ADIP PF11559.3 GAP88972.1 - 0.37 10.6 4.1 0.52 10.2 2.8 1.4 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding XhlA PF10779.4 GAP88972.1 - 0.39 10.6 2.5 0.7 9.8 1.8 1.3 1 0 0 1 1 1 0 Haemolysin XhlA DUF2360 PF10152.4 GAP88972.1 - 0.4 10.9 6.4 0.51 10.6 4.4 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) IncA PF04156.9 GAP88972.1 - 1.3 8.6 5.0 0.74 9.3 2.0 1.3 1 1 0 1 1 1 0 IncA protein Mei5 PF10376.4 GAP88972.1 - 2 7.8 7.1 0.58 9.6 1.6 1.9 1 1 1 2 2 2 0 Double-strand recombination repair protein Asp PF00026.18 GAP88973.1 - 1.5e-55 188.6 0.5 1.8e-55 188.4 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAP88973.1 - 0.0013 18.7 0.1 0.0078 16.1 0.0 2.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal HSP70 PF00012.15 GAP88974.1 - 6.5e-57 192.7 2.0 1.2e-53 181.9 0.0 3.1 3 1 1 4 4 4 2 Hsp70 protein MreB_Mbl PF06723.8 GAP88974.1 - 0.0011 17.7 0.0 0.0024 16.5 0.0 1.5 1 0 0 1 1 1 1 MreB/Mbl protein adh_short PF00106.20 GAP88975.1 - 3.4e-29 101.8 0.2 4.6e-29 101.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP88975.1 - 6.2e-17 62.1 0.0 7.7e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP88975.1 - 6.2e-12 45.5 0.2 9.6e-12 44.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAP88975.1 - 0.0013 18.2 0.1 0.0038 16.6 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAP88975.1 - 0.018 15.0 1.1 0.11 12.5 0.2 2.4 2 2 0 2 2 2 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 GAP88975.1 - 0.048 13.4 0.3 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DNA_gyraseA_C PF03989.8 GAP88975.1 - 0.12 11.6 0.0 0.2 11.0 0.0 1.5 1 1 0 1 1 1 0 DNA gyrase C-terminal domain, beta-propeller Acetyltransf_7 PF13508.1 GAP88976.1 - 5.1e-06 26.5 0.0 1.8e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAP88976.1 - 0.00017 21.5 0.0 0.005 16.8 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.1 GAP88976.1 - 0.0044 17.5 0.1 0.092 13.3 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Ribosomal_S7 PF00177.16 GAP88977.1 - 1.3e-41 141.6 1.1 3.2e-41 140.3 0.7 1.6 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e Cyt-b5 PF00173.23 GAP88978.1 - 4.9e-09 35.8 0.0 8.9e-09 35.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3682 PF12446.3 GAP88978.1 - 0.01 16.1 8.2 0.015 15.5 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Cu_bind_like PF02298.12 GAP88979.1 - 0.014 15.1 0.7 0.066 13.0 0.5 2.0 1 1 0 1 1 1 0 Plastocyanin-like domain Copper-bind PF00127.15 GAP88979.1 - 0.074 13.2 0.3 0.16 12.1 0.2 1.6 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family CENP-X PF09415.5 GAP88980.1 - 1.9e-26 91.6 0.0 3.2e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.18 GAP88980.1 - 0.022 14.8 0.1 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Mito_carr PF00153.22 GAP88981.1 - 1.1e-66 220.6 4.5 1.6e-23 82.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S25 PF03297.10 GAP88982.1 - 2.8e-39 133.3 5.1 3.1e-39 133.2 3.5 1.0 1 0 0 1 1 1 1 S25 ribosomal protein RNA_pol_Rpc34 PF05158.7 GAP88982.1 - 0.013 14.6 0.2 0.02 14.0 0.0 1.3 1 1 0 1 1 1 0 RNA polymerase Rpc34 subunit HTH_24 PF13412.1 GAP88982.1 - 0.014 14.7 0.1 0.021 14.2 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 GAP88982.1 - 0.024 14.2 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 MarR family DDRGK PF09756.4 GAP88982.1 - 0.033 13.6 0.3 0.046 13.1 0.2 1.2 1 0 0 1 1 1 0 DDRGK domain FeoC PF09012.5 GAP88982.1 - 0.088 12.5 0.2 0.29 10.8 0.0 1.8 1 1 1 2 2 2 0 FeoC like transcriptional regulator UPF0258 PF06789.7 GAP88982.1 - 0.11 12.5 0.1 0.12 12.4 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) TrmB PF01978.14 GAP88982.1 - 0.12 12.1 0.3 0.16 11.7 0.2 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB F-box-like PF12937.2 GAP88983.1 - 0.012 15.3 0.4 0.034 13.8 0.3 1.9 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 GAP88983.1 - 0.098 12.3 0.4 0.26 10.9 0.3 1.8 1 0 0 1 1 1 0 F-box domain DUF2146 PF10220.4 GAP88986.1 - 0.025 12.5 2.0 0.047 11.6 1.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) KOW PF00467.24 GAP88987.1 - 3.5e-08 32.8 0.5 9e-08 31.5 0.3 1.7 1 0 0 1 1 1 1 KOW motif Coa1 PF08695.5 GAP88988.1 - 1.7e-32 111.3 0.0 2.1e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Ribosomal_L3 PF00297.17 GAP88989.1 - 9e-32 110.5 3.4 9.6e-31 107.1 2.4 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 DUF814 PF05670.8 GAP88990.1 - 2.3e-14 53.0 0.0 3.9e-08 33.0 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF814) PITH PF06201.8 GAP88991.1 - 6.7e-40 136.3 2.1 8.5e-40 136.0 0.4 1.8 2 1 0 2 2 2 1 PITH domain Zip PF02535.17 GAP88991.1 - 0.029 13.3 1.6 0.04 12.9 1.1 1.2 1 1 0 1 1 1 0 ZIP Zinc transporter Rrn6 PF10214.4 GAP88992.1 - 9.1e-58 196.0 0.0 1.2e-57 195.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.7 GAP88993.1 - 3.5e-22 78.1 0.0 6.8e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Mnd1 PF03962.10 GAP88993.1 - 0.28 10.8 3.1 0.7 9.5 2.0 1.6 2 0 0 2 2 2 0 Mnd1 family Striatin PF08232.7 GAP88993.1 - 0.49 10.7 6.9 0.21 11.9 2.9 1.5 1 1 0 1 1 1 0 Striatin family Filament PF00038.16 GAP88993.1 - 0.58 9.5 10.8 0.47 9.8 6.0 1.8 2 0 0 2 2 2 0 Intermediate filament protein zinc_ribbon_6 PF14599.1 GAP88994.1 - 5.6e-25 86.9 0.3 5.6e-25 86.9 0.2 4.3 4 1 0 4 4 4 1 Zinc-ribbon zf-CHY PF05495.7 GAP88994.1 - 1.7e-17 63.3 19.1 1.7e-17 63.3 13.2 4.2 3 1 0 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.1 GAP88994.1 - 1.7e-09 37.3 8.5 1.7e-09 37.3 5.9 4.7 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAP88994.1 - 7.5e-07 29.0 7.6 7.5e-07 29.0 5.3 5.1 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAP88994.1 - 9.1e-06 25.3 8.9 9.1e-06 25.3 6.1 6.6 3 2 1 4 4 4 1 zinc-RING finger domain Complex1_LYR PF05347.10 GAP88995.1 - 0.00049 19.8 5.1 0.00049 19.8 3.6 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Mito_carr PF00153.22 GAP88996.1 - 1.9e-46 155.6 8.9 3.2e-17 62.0 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Mob1_phocein PF03637.12 GAP88997.1 - 1.3e-68 230.0 0.0 1.7e-68 229.7 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family TPR_15 PF13429.1 GAP88998.1 - 0.085 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat PAD_porph PF04371.10 GAP88998.1 - 0.13 11.3 0.0 0.54 9.2 0.0 1.9 3 0 0 3 3 3 0 Porphyromonas-type peptidyl-arginine deiminase Glyco_hyd_65N_2 PF14498.1 GAP88999.1 - 0.031 13.9 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain LSM PF01423.17 GAP89000.1 - 6.3e-12 44.8 0.0 1.1e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 LSM domain AAA_13 PF13166.1 GAP89001.1 - 0.048 12.1 6.4 0.068 11.6 4.4 1.1 1 0 0 1 1 1 0 AAA domain DUF4473 PF14747.1 GAP89001.1 - 0.1 12.8 2.0 0.25 11.5 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) ISG65-75 PF11727.3 GAP89001.1 - 0.11 11.5 3.7 0.17 10.9 2.6 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein Rifin_STEVOR PF02009.11 GAP89001.1 - 0.25 10.9 9.6 0.073 12.7 1.1 2.0 1 1 1 2 2 2 0 Rifin/stevor family Mnd1 PF03962.10 GAP89001.1 - 0.32 10.6 4.5 0.52 9.9 3.1 1.3 1 0 0 1 1 1 0 Mnd1 family Prominin PF05478.6 GAP89001.1 - 0.51 7.8 5.4 0.66 7.4 3.7 1.1 1 0 0 1 1 1 0 Prominin DUF3584 PF12128.3 GAP89001.1 - 1.8 5.7 13.4 2.4 5.3 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) YlqD PF11068.3 GAP89001.1 - 3.2 7.8 7.8 5 7.1 5.0 1.6 1 1 0 1 1 1 0 YlqD protein DUF883 PF05957.8 GAP89001.1 - 4 7.8 10.9 7.8 6.9 5.6 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) IFT57 PF10498.4 GAP89001.1 - 8.3 5.0 8.8 12 4.4 6.1 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 NUDIX PF00293.23 GAP89002.1 - 7.7e-15 54.7 0.5 8.7e-15 54.5 0.3 1.0 1 0 0 1 1 1 1 NUDIX domain ATE_C PF04377.10 GAP89003.1 - 8.5e-42 142.2 0.0 1.7e-41 141.2 0.0 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 GAP89003.1 - 6e-15 54.8 2.6 1.2e-14 53.8 1.8 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus adh_short PF00106.20 GAP89004.1 - 2.4e-16 60.1 0.7 2.4e-16 60.1 0.5 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAP89004.1 - 1.7e-08 34.3 1.4 2.9e-08 33.5 0.2 1.8 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 GAP89004.1 - 9.5e-07 28.8 0.0 1e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase F420_oxidored PF03807.12 GAP89004.1 - 0.00099 19.4 0.8 0.0093 16.3 0.1 2.5 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 GAP89004.1 - 0.0019 18.3 0.1 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.21 GAP89004.1 - 0.006 16.1 0.0 0.025 14.1 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 GAP89004.1 - 0.0064 16.5 0.2 0.015 15.2 0.2 1.6 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAP89004.1 - 0.17 11.3 0.7 0.53 9.6 0.1 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family RNase_PH PF01138.16 GAP89005.1 - 1.4e-14 54.5 7.7 2e-08 34.6 1.4 2.6 2 1 0 3 3 3 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 GAP89005.1 - 0.067 13.1 0.5 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 AJAP1_PANP_C PF15298.1 GAP89005.1 - 0.11 12.3 11.4 0.89 9.3 1.3 2.3 2 0 0 2 2 2 0 AJAP1/PANP C-terminus Dicty_REP PF05086.7 GAP89005.1 - 0.12 10.1 7.7 1 7.0 0.3 2.0 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Cytochrom_C PF00034.16 GAP89007.1 - 6.7e-11 42.8 0.0 1e-10 42.2 0.0 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 GAP89007.1 - 1.8e-09 37.6 0.9 9.8e-09 35.2 0.6 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 GAP89007.1 - 0.00035 20.0 1.7 0.00066 19.1 0.3 2.0 1 1 0 2 2 2 1 Cytochrome c-550 domain Cytochrom_C1 PF02167.10 GAP89007.1 - 0.016 14.8 0.1 0.049 13.2 0.0 1.6 1 1 1 2 2 2 0 Cytochrome C1 family Cytochrome-c551 PF10643.4 GAP89007.1 - 0.036 13.3 0.1 0.044 13.0 0.1 1.4 1 1 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 AAA PF00004.24 GAP89009.1 - 4.6e-91 301.8 0.0 9.4e-49 164.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAP89009.1 - 3.5e-13 49.8 0.6 4.6e-05 23.5 0.2 4.3 2 2 0 2 2 2 2 AAA domain AAA_2 PF07724.9 GAP89009.1 - 2.7e-12 46.9 0.0 7.3e-05 22.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 GAP89009.1 - 3.5e-12 45.8 0.0 3.7e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 GAP89009.1 - 3.6e-11 43.9 0.3 2.8e-05 24.9 0.0 3.3 3 1 0 3 3 2 2 AAA domain AAA_33 PF13671.1 GAP89009.1 - 7.7e-11 42.0 0.0 8.5e-05 22.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 GAP89009.1 - 1.6e-10 40.9 0.0 0.00027 20.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 GAP89009.1 - 5.6e-10 39.0 0.1 0.0014 18.3 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAP89009.1 - 1.6e-09 38.0 6.0 0.00036 20.5 0.0 4.3 4 2 0 4 4 3 2 AAA ATPase domain AAA_25 PF13481.1 GAP89009.1 - 1e-08 34.8 9.8 0.039 13.3 0.1 4.9 3 2 2 5 5 5 2 AAA domain AAA_19 PF13245.1 GAP89009.1 - 1.7e-08 34.0 0.0 0.0043 16.7 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain IstB_IS21 PF01695.12 GAP89009.1 - 7e-08 32.0 0.0 0.0073 15.7 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 GAP89009.1 - 1.4e-07 30.8 0.3 0.017 14.2 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 GAP89009.1 - 3.6e-07 29.4 0.0 0.004 16.2 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin NACHT PF05729.7 GAP89009.1 - 9.9e-07 28.5 0.3 0.045 13.4 0.0 3.6 4 0 0 4 4 4 2 NACHT domain AAA_28 PF13521.1 GAP89009.1 - 1.6e-06 28.1 0.0 0.086 12.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.17 GAP89009.1 - 1.6e-06 28.2 0.0 0.073 13.2 0.0 2.8 2 1 0 2 2 2 2 RNA helicase TIP49 PF06068.8 GAP89009.1 - 1.9e-06 26.8 0.1 0.032 12.9 0.1 2.5 2 1 1 3 3 3 2 TIP49 C-terminus AAA_18 PF13238.1 GAP89009.1 - 2.9e-06 27.6 0.0 0.048 13.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain KaiC PF06745.8 GAP89009.1 - 6.5e-06 25.4 0.4 0.071 12.2 0.0 3.3 2 1 1 3 3 3 2 KaiC Cytidylate_kin2 PF13189.1 GAP89009.1 - 1.5e-05 24.9 0.0 0.0056 16.5 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_3 PF07726.6 GAP89009.1 - 2.7e-05 23.7 0.0 0.063 12.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 GAP89009.1 - 5e-05 22.9 0.0 0.3 10.5 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 GAP89009.1 - 5.5e-05 23.4 0.0 0.29 11.4 0.0 2.8 2 0 0 2 2 2 2 ABC transporter Arch_ATPase PF01637.13 GAP89009.1 - 7.4e-05 22.5 0.1 1.5 8.4 0.0 3.7 2 2 2 4 4 4 2 Archaeal ATPase Sigma54_activat PF00158.21 GAP89009.1 - 9.2e-05 21.9 0.0 0.3 10.5 0.0 2.9 3 0 0 3 3 3 2 Sigma-54 interaction domain PhoH PF02562.11 GAP89009.1 - 0.00011 21.5 0.1 0.23 10.6 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein NB-ARC PF00931.17 GAP89009.1 - 0.00012 21.0 0.1 0.24 10.2 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activ_2 PF14532.1 GAP89009.1 - 0.00014 21.9 0.2 0.29 11.1 0.0 2.7 3 0 0 3 3 2 2 Sigma-54 interaction domain DUF815 PF05673.8 GAP89009.1 - 0.00021 20.3 0.0 0.11 11.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 GAP89009.1 - 0.00021 20.8 0.0 0.42 10.0 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain SKI PF01202.17 GAP89009.1 - 0.00038 20.3 3.4 0.64 9.8 0.0 3.3 3 0 0 3 3 3 2 Shikimate kinase Rad17 PF03215.10 GAP89009.1 - 0.0006 18.6 0.0 0.3 9.7 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein UPF0079 PF02367.12 GAP89009.1 - 0.00068 19.2 0.1 0.41 10.2 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 GAP89009.1 - 0.001 18.6 0.4 1.4 8.4 0.1 2.4 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 GAP89009.1 - 0.001 18.9 0.0 1.1 9.0 0.0 2.8 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit AAA_11 PF13086.1 GAP89009.1 - 0.0017 17.9 0.2 0.95 8.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.10 GAP89009.1 - 0.0038 16.9 0.5 1.1 8.9 0.0 3.0 3 0 0 3 3 3 1 NTPase T2SE PF00437.15 GAP89009.1 - 0.0085 15.0 0.0 7.8 5.3 0.0 3.3 3 0 0 3 3 3 0 Type II/IV secretion system protein Parvo_NS1 PF01057.12 GAP89009.1 - 0.0089 14.9 0.1 1.3 7.8 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Vps4_C PF09336.5 GAP89009.1 - 0.021 14.7 0.2 3.7 7.4 0.0 3.4 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain AFG1_ATPase PF03969.11 GAP89009.1 - 0.021 13.6 0.0 1.4 7.6 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase DAP3 PF10236.4 GAP89009.1 - 0.022 13.6 0.1 6.2 5.6 0.0 3.4 3 1 1 4 4 4 0 Mitochondrial ribosomal death-associated protein 3 AAA_30 PF13604.1 GAP89009.1 - 0.028 13.9 2.3 1.3 8.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain Bac_DnaA PF00308.13 GAP89009.1 - 0.045 13.3 0.0 4.2 6.9 0.0 3.0 3 1 0 3 3 2 0 Bacterial dnaA protein DUF2075 PF09848.4 GAP89009.1 - 0.052 12.5 0.0 7.2 5.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MCM PF00493.18 GAP89009.1 - 0.053 12.3 0.0 0.32 9.7 0.0 2.0 2 0 0 2 2 2 0 MCM2/3/5 family SRPRB PF09439.5 GAP89009.1 - 0.2 10.8 0.8 13 4.9 0.0 2.8 3 0 0 3 3 2 0 Signal recognition particle receptor beta subunit AAA_23 PF13476.1 GAP89009.1 - 0.32 11.2 4.7 2.5 8.3 0.0 3.2 3 1 0 3 3 3 0 AAA domain AAA_10 PF12846.2 GAP89009.1 - 0.71 9.2 8.3 7.3 5.9 0.0 4.4 4 1 0 5 5 5 0 AAA-like domain Snf7 PF03357.16 GAP89010.1 - 2.5e-32 111.5 3.6 3e-32 111.3 2.5 1.0 1 0 0 1 1 1 1 Snf7 Nup54 PF13874.1 GAP89010.1 - 0.56 9.8 8.7 2.1 8.0 0.1 2.5 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 DUF2293 PF10056.4 GAP89011.1 - 4.4e-07 29.7 0.1 0.00049 20.0 0.0 2.8 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2293) OSCP PF00213.13 GAP89012.1 - 1.4e-43 148.7 3.3 1.8e-43 148.3 2.3 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Glyco_hydro_63 PF03200.11 GAP89013.1 - 3e-09 35.3 5.4 5.7e-07 27.7 0.1 3.6 3 1 0 3 3 3 2 Mannosyl oligosaccharide glucosidase RasGEF PF00617.14 GAP89014.1 - 5.8e-44 150.0 0.5 9.6e-44 149.3 0.3 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAP89014.1 - 1.7e-13 50.5 0.0 6.6e-13 48.6 0.0 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif Miro PF08477.8 GAP89014.1 - 7.6e-12 45.7 0.0 1e-10 42.1 0.0 2.8 3 0 0 3 3 3 1 Miro-like protein Ras PF00071.17 GAP89014.1 - 0.00019 20.8 0.0 0.0014 18.0 0.0 2.3 3 0 0 3 3 3 1 Ras family ABC_tran PF00005.22 GAP89014.1 - 0.026 14.8 0.4 0.68 10.2 0.0 3.0 3 1 0 3 3 3 0 ABC transporter FtsK_SpoIIIE PF01580.13 GAP89014.1 - 0.034 13.5 0.0 4.7 6.6 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_21 PF13304.1 GAP89014.1 - 0.099 12.5 0.0 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.20 GAP89015.1 - 5.7e-17 61.7 0.0 7.6e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP89015.1 - 9.1e-09 34.7 0.0 1.2e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 GAP89015.1 - 6.8e-06 25.2 0.0 1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAP89015.1 - 1.2e-05 25.2 0.0 1.8e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAP89015.1 - 0.00047 19.7 0.0 0.00079 19.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 GAP89015.1 - 0.0029 16.6 0.0 0.01 14.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 GAP89015.1 - 0.0077 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.6 GAP89015.1 - 0.16 10.6 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 GAP89016.1 - 3.2e-11 43.4 0.0 8.2e-11 42.0 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 GAP89016.1 - 1.2e-05 24.1 0.0 4.9e-05 22.1 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 GAP89016.1 - 0.00021 20.5 0.0 0.00029 20.1 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 GAP89016.1 - 0.012 15.1 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.20 GAP89017.1 - 9.1e-10 38.1 0.0 1.5e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP89017.1 - 0.00011 21.4 0.0 0.00047 19.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase YscJ_FliF_C PF08345.6 GAP89018.1 - 3.1 7.7 5.2 4.6 7.1 1.8 2.0 2 0 0 2 2 2 0 Flagellar M-ring protein C-terminal DUF726 PF05277.7 GAP89019.1 - 3.7e-100 335.1 0.0 5.2e-100 334.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Glu-tRNAGln PF02686.10 GAP89020.1 - 0.00042 20.0 0.0 0.00098 18.8 0.0 1.6 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit AAA PF00004.24 GAP89021.1 - 7.9e-10 39.0 0.0 1.7e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SNAP PF14938.1 GAP89023.1 - 1.1e-109 365.9 11.8 1.3e-109 365.7 8.2 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 GAP89023.1 - 2.7e-06 27.2 10.6 0.0032 17.3 0.0 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAP89023.1 - 0.00011 21.7 12.8 0.28 11.2 0.4 5.9 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAP89023.1 - 0.0007 19.8 8.6 2.7 8.6 0.3 5.5 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAP89023.1 - 0.0027 17.2 11.5 0.31 10.7 0.2 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAP89023.1 - 0.0028 17.2 15.6 0.28 10.8 0.6 3.8 1 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.1 GAP89023.1 - 0.022 14.5 7.6 1.5 8.7 0.6 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TRAPPC-Trs85 PF12739.2 GAP89023.1 - 0.03 12.9 3.2 2.6 6.6 0.2 2.9 1 1 0 2 2 2 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_7 PF13176.1 GAP89023.1 - 0.057 13.2 9.6 5.8 6.9 0.2 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF2521 PF10730.4 GAP89023.1 - 0.063 13.0 0.2 0.15 11.9 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2521) TPR_16 PF13432.1 GAP89023.1 - 0.21 12.2 13.1 1.1 10.0 0.9 3.6 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAP89023.1 - 0.34 11.6 9.5 4.1 8.3 0.1 5.2 2 1 3 5 5 5 0 Tetratricopeptide repeat NUC173 PF08161.7 GAP89024.1 - 9.6e-79 263.3 0.2 9e-75 250.3 0.0 3.9 4 0 0 4 4 4 2 NUC173 domain Vac14_Fab1_bd PF12755.2 GAP89024.1 - 0.0097 16.2 0.1 14 6.1 0.0 3.9 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 GAP89024.1 - 0.012 15.6 1.4 13 6.1 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.1 GAP89024.1 - 1.2 9.4 8.5 0.56 10.5 0.4 4.1 4 1 0 4 4 4 0 HEAT repeats V-SNARE PF05008.10 GAP89025.1 - 1.1e-22 79.9 2.9 1.1e-22 79.9 2.0 1.7 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 GAP89025.1 - 7.9e-18 64.2 1.7 7.9e-18 64.2 1.2 2.2 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 GAP89025.1 - 0.0014 18.2 0.1 0.0037 16.9 0.1 1.7 1 0 0 1 1 1 1 Sec20 Laminin_I PF06008.9 GAP89025.1 - 0.0023 17.2 0.7 0.0023 17.2 0.5 1.9 2 0 0 2 2 2 1 Laminin Domain I Fusion_gly PF00523.13 GAP89025.1 - 0.093 10.7 1.3 0.27 9.2 0.1 2.1 2 1 0 2 2 2 0 Fusion glycoprotein F0 Synaptobrevin PF00957.16 GAP89025.1 - 0.18 11.4 5.8 0.052 13.1 0.8 2.4 2 1 1 3 3 3 0 Synaptobrevin Glyco_hydro_cc PF11790.3 GAP89026.1 - 2.1e-27 96.1 0.0 2.5e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Amino_oxidase PF01593.19 GAP89027.1 - 4.1e-13 49.2 0.1 2.4e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAP89027.1 - 9.2e-13 48.0 0.1 2.2e-12 46.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAP89027.1 - 4.2e-06 26.9 0.1 0.0011 19.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAP89027.1 - 5.4e-06 25.5 0.1 0.00011 21.2 0.1 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAP89027.1 - 3.9e-05 23.6 0.0 0.002 18.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAP89027.1 - 6.2e-05 22.8 0.0 0.42 10.3 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.9 GAP89027.1 - 0.00098 17.6 0.1 0.026 13.0 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 GAP89027.1 - 0.0042 16.2 0.0 0.0053 15.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 GAP89027.1 - 0.0089 14.9 0.2 0.017 14.0 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 GAP89027.1 - 0.028 14.8 0.1 0.066 13.6 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAP89027.1 - 0.082 11.7 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 GAP89027.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Thi4 family CtaG_Cox11 PF04442.9 GAP89028.1 - 5.9e-57 191.7 0.0 1.2e-56 190.7 0.0 1.5 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein CtaG/Cox11 HAD_2 PF13419.1 GAP89030.1 - 6e-13 49.3 0.1 7.7e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAP89030.1 - 0.015 15.0 0.2 0.039 13.6 0.2 1.8 1 1 1 2 2 2 0 HAD-hyrolase-like DUF3433 PF11915.3 GAP89032.1 - 9.8e-09 35.2 1.9 9.8e-09 35.2 1.3 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) Fun_ATP-synt_8 PF05933.8 GAP89032.1 - 1.2 9.2 5.8 0.12 12.4 0.4 2.1 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) DUF647 PF04884.9 GAP89034.1 - 1.5e-93 312.6 0.8 1.8e-93 312.3 0.5 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Cyto_heme_lyase PF01265.12 GAP89035.1 - 2.9e-87 292.5 2.5 2.7e-82 276.2 0.0 2.0 1 1 1 2 2 2 2 Cytochrome c/c1 heme lyase GHMP_kinases_N PF00288.21 GAP89037.1 - 1.8e-10 40.7 3.7 4.1e-10 39.5 1.1 2.5 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 GAP89037.1 - 0.005 17.0 0.2 0.045 13.9 0.0 2.5 3 0 0 3 3 3 1 GHMP kinases C terminal MFS_1 PF07690.11 GAP89038.1 - 8.6e-25 87.1 31.2 8.6e-25 87.1 21.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP89038.1 - 1e-11 44.0 32.6 5.2e-11 41.7 22.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter LacAB_rpiB PF02502.13 GAP89038.1 - 0.11 12.1 0.3 0.23 11.1 0.2 1.4 1 0 0 1 1 1 0 Ribose/Galactose Isomerase NACHT PF05729.7 GAP89039.1 - 1.8e-08 34.1 0.0 5.6e-08 32.6 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 GAP89039.1 - 8.9e-05 22.5 0.0 0.021 14.7 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAP89039.1 - 0.0024 17.9 0.0 0.03 14.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAP89039.1 - 0.021 15.1 0.0 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 GAP89039.1 - 0.025 15.4 0.0 0.085 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain DUF2408 PF10303.4 GAP89039.1 - 0.056 13.5 0.1 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) DUF3071 PF11268.3 GAP89040.1 - 0.017 14.8 0.3 0.027 14.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) Pyr_redox PF00070.22 GAP89040.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mannitol_dh_C PF08125.8 GAP89044.1 - 1.6e-46 158.5 0.0 2.3e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 GAP89044.1 - 5.8e-21 75.0 0.2 1.5e-20 73.7 0.0 1.8 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain Coatomer_WDAD PF04053.9 GAP89045.1 - 4.1e-166 553.1 0.0 1.7e-165 551.1 0.0 1.9 2 1 1 3 3 3 1 Coatomer WD associated region WD40 PF00400.27 GAP89045.1 - 7e-46 152.5 11.5 4.6e-11 42.1 0.2 8.1 9 0 0 9 9 9 6 WD domain, G-beta repeat Nup160 PF11715.3 GAP89045.1 - 6.9e-05 21.1 3.9 0.017 13.3 0.0 3.9 1 1 2 4 4 4 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 GAP89045.1 - 0.0012 18.6 0.0 0.6 9.9 0.0 3.5 2 2 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Cwf_Cwc_15 PF04889.7 GAP89045.1 - 2.8 7.5 14.9 3.9 7.1 10.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pyridox_oxidase PF01243.15 GAP89047.1 - 1.8e-10 40.6 0.0 3.4e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase TP_methylase PF00590.15 GAP89048.1 - 9.9e-12 45.0 0.0 1.8e-11 44.1 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases zf-C2H2_jaz PF12171.3 GAP89049.1 - 1e-06 28.6 0.1 1.9e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF1777 PF08648.7 GAP89049.1 - 4.5e-05 23.2 8.6 4.5e-05 23.2 5.9 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) zf-met PF12874.2 GAP89049.1 - 9.3e-05 22.4 0.2 0.00018 21.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 GAP89049.1 - 0.077 13.3 0.3 0.95 9.9 0.1 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Vfa1 PF08432.5 GAP89049.1 - 5.7 6.9 12.5 3.6 7.5 4.5 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 UQ_con PF00179.21 GAP89050.1 - 2.9e-35 120.7 0.0 3.2e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAP89050.1 - 0.0053 16.5 0.3 0.01 15.5 0.2 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 GAP89050.1 - 0.058 13.3 0.1 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 RWD domain Glyco_trans_1_4 PF13692.1 GAP89051.1 - 1.4e-22 80.2 0.1 6.1e-22 78.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 GAP89051.1 - 9e-07 28.4 0.0 1.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 GAP89051.1 - 0.0025 18.0 0.0 0.0057 16.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 CTP_synth_N PF06418.9 GAP89052.1 - 4.5e-112 373.6 0.1 6e-112 373.2 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 GAP89052.1 - 9.2e-50 168.7 0.0 1.6e-49 167.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 GAP89052.1 - 0.00024 20.6 0.0 0.00055 19.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 GAP89052.1 - 0.019 14.4 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Cation_efflux PF01545.16 GAP89053.1 - 3.3e-62 210.1 0.3 4.5e-62 209.7 0.2 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 GAP89053.1 - 0.0083 15.1 74.3 0.32 9.9 18.0 3.6 1 1 1 2 2 2 2 ZIP Zinc transporter Mito_carr PF00153.22 GAP89054.1 - 3.7e-58 193.2 5.4 8.6e-20 70.2 0.2 3.5 4 0 0 4 4 4 3 Mitochondrial carrier protein His_Phos_1 PF00300.17 GAP89055.1 - 1.4e-06 28.4 0.0 7.2e-05 22.9 0.0 3.0 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) YokU PF14122.1 GAP89055.1 - 0.072 12.8 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 YokU-like protein DUF3433 PF11915.3 GAP89056.1 - 4.1e-33 113.3 13.2 2.9e-19 69.0 0.4 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Peptidase_C13 PF01650.13 GAP89057.1 - 3.1e-40 138.1 0.2 4e-40 137.7 0.2 1.1 1 0 0 1 1 1 1 Peptidase C13 family TFIIIC_delta PF12657.2 GAP89058.1 - 2e-14 53.7 0.0 8.9e-14 51.5 0.0 2.1 1 1 0 1 1 1 1 Transcription factor IIIC subunit delta N-term Nop14 PF04147.7 GAP89058.1 - 0.07 11.0 9.0 0.093 10.6 6.2 1.0 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 GAP89058.1 - 0.52 9.9 4.3 0.75 9.4 3.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein LysM PF01476.15 GAP89060.1 - 3.7e-12 45.9 0.0 3.8e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 LysM domain CorA PF01544.13 GAP89061.1 - 0.047 12.7 0.0 0.089 11.8 0.0 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF892 PF05974.7 GAP89062.1 - 0.034 13.9 0.1 0.057 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF892) Glycogen_syn PF05693.8 GAP89063.1 - 0 1132.5 0.0 0 1132.3 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 GAP89063.1 - 6.9e-07 28.8 0.0 0.0012 18.2 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 GAP89063.1 - 3.9e-05 23.8 0.0 8.3e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain F-box-like PF12937.2 GAP89064.1 - 3.2e-06 26.7 0.5 8.8e-06 25.3 0.4 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 GAP89064.1 - 0.0036 16.9 5.3 0.035 13.7 2.7 2.9 2 1 0 2 2 2 1 F-box domain LRR_8 PF13855.1 GAP89064.1 - 0.089 12.5 0.1 1.3 8.8 0.0 2.7 3 0 0 3 3 3 0 Leucine rich repeat cobW PF02492.14 GAP89065.1 - 5.8e-35 120.3 0.0 7.8e-35 119.9 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 GAP89065.1 - 0.0035 17.0 0.0 0.006 16.2 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 GAP89065.1 - 0.025 14.1 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 GAP89065.1 - 0.034 13.9 0.1 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_10 PF12846.2 GAP89065.1 - 0.049 13.0 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 GAP89065.1 - 0.06 13.3 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF463 PF04317.7 GAP89065.1 - 0.065 11.7 0.1 0.091 11.3 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA_29 PF13555.1 GAP89065.1 - 0.087 12.3 0.0 0.69 9.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Stm1_N PF09598.5 GAP89066.1 - 1.4 9.6 5.2 1.7 9.4 0.5 2.2 2 0 0 2 2 2 0 Stm1 BBE PF08031.7 GAP89067.1 - 1.6e-05 24.7 0.0 2.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF1754 PF08555.5 GAP89069.1 - 4.7e-07 30.3 8.4 4.9e-07 30.2 5.8 1.0 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) DUF4448 PF14610.1 GAP89069.1 - 0.17 11.3 0.6 0.17 11.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF572 PF04502.8 GAP89070.1 - 0.085 12.0 10.1 0.11 11.6 7.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF605 PF04652.11 GAP89070.1 - 0.12 11.7 28.7 0.14 11.4 19.9 1.1 1 0 0 1 1 1 0 Vta1 like CTP_transf_1 PF01148.15 GAP89071.1 - 2.5e-07 30.6 12.5 4.8e-06 26.4 6.1 3.0 2 1 0 2 2 2 1 Cytidylyltransferase family Fungal_trans PF04082.13 GAP89072.1 - 4.3e-18 65.1 0.0 7.7e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP89072.1 - 0.00014 21.7 10.1 0.00014 21.7 7.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 GAP89073.1 - 1.3e-40 139.2 48.7 1.3e-40 139.2 33.8 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAP89073.1 - 9e-12 43.9 17.8 1.3e-11 43.4 12.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) WTF PF03303.8 GAP89073.1 - 0.13 11.6 2.2 0.31 10.4 1.5 1.7 1 0 0 1 1 1 0 WTF protein ATP-synt_C PF00137.16 GAP89074.1 - 0.017 14.9 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 ATP synthase subunit C MoeZ_MoeB PF05237.8 GAP89075.1 - 0.019 14.5 0.3 0.22 11.1 0.0 2.2 2 0 0 2 2 2 0 MoeZ/MoeB domain Apc13p PF05839.6 GAP89076.1 - 7e-33 112.4 0.1 8.6e-33 112.1 0.1 1.0 1 0 0 1 1 1 1 Apc13p protein TRAPP PF04051.11 GAP89077.1 - 9.8e-36 122.5 0.0 1.2e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component CRAL_TRIO PF00650.15 GAP89078.1 - 1.2e-40 138.5 0.0 2.2e-40 137.7 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAP89078.1 - 3.5e-09 36.6 0.7 7.1e-09 35.6 0.5 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 GAP89078.1 - 1.1e-05 25.3 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Pol_alpha_B_N PF08418.5 GAP89080.1 - 4.6e-57 193.4 0.2 6.9e-57 192.8 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 GAP89080.1 - 1.2e-39 135.7 0.1 1.7e-39 135.2 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Prp19_bind PF06991.6 GAP89081.1 - 4.1e-48 164.0 37.9 4.1e-48 164.0 26.3 2.2 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain Alb1 PF09135.6 GAP89082.1 - 5.4e-20 72.0 10.3 5.4e-20 72.0 7.1 1.9 1 1 1 2 2 2 1 Alb1 Z1 PF10593.4 GAP89082.1 - 0.11 11.7 1.4 0.13 11.4 0.9 1.1 1 0 0 1 1 1 0 Z1 domain DUF4168 PF13767.1 GAP89082.1 - 0.41 11.3 3.6 0.51 11.0 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4168) V_ATPase_I PF01496.14 GAP89082.1 - 1.2 6.8 3.0 1.4 6.7 2.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GET2 PF08690.5 GAP89082.1 - 3.1 6.9 5.2 4 6.5 3.6 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 ATP-synt_B PF00430.13 GAP89082.1 - 6.4 6.5 9.7 3.2 7.5 5.2 1.6 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) UCH PF00443.24 GAP89083.1 - 1.8e-37 128.8 0.0 2.5e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAP89083.1 - 4.1e-05 23.1 0.0 7.7e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Abhydrolase_2 PF02230.11 GAP89084.1 - 7.8e-16 58.1 0.0 2.6e-14 53.1 0.0 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 GAP89084.1 - 2.8e-07 30.3 0.0 4.4e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP89084.1 - 0.00014 21.8 0.1 0.013 15.3 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 GAP89084.1 - 0.0013 18.2 0.0 0.0024 17.3 0.0 1.5 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.3 GAP89084.1 - 0.035 13.9 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Putative lysophospholipase Pkinase PF00069.20 GAP89085.1 - 8.9e-23 80.7 0.0 1.4e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP89085.1 - 8.4e-15 54.5 0.0 1.3e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 GAP89085.1 - 0.00027 20.0 0.1 0.00058 18.9 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 GAP89085.1 - 0.013 14.3 0.1 0.019 13.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 GAP89085.1 - 0.12 12.0 0.3 0.55 9.9 0.1 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family Sec8_exocyst PF04048.9 GAP89086.1 - 1.9e-49 166.9 1.7 4.7e-49 165.6 1.2 1.7 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 GAP89086.1 - 3.2e-10 39.3 0.8 5.9e-10 38.5 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Anti-adapt_IraP PF10796.4 GAP89086.1 - 0.073 13.4 2.2 0.56 10.6 0.0 3.1 3 0 0 3 3 3 0 Sigma-S stabilisation anti-adaptor protein SMI1_KNR4 PF09346.5 GAP89088.1 - 1.1e-34 119.2 0.0 2.1e-34 118.3 0.0 1.5 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) UPF0220 PF05255.6 GAP89089.1 - 9.7e-58 194.0 0.8 6.4e-55 184.9 0.6 2.0 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0220) BLVR PF06375.6 GAP89089.1 - 0.011 15.5 1.2 0.014 15.2 0.8 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Mito_fiss_reg PF05308.6 GAP89089.1 - 0.022 14.1 1.3 0.031 13.6 0.9 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator V-ATPase_C PF03223.10 GAP89089.1 - 0.038 12.9 1.1 0.051 12.4 0.8 1.1 1 0 0 1 1 1 0 V-ATPase subunit C Mito_carr PF00153.22 GAP89090.1 - 9.4e-61 201.5 11.0 8.5e-21 73.4 0.1 4.0 4 0 0 4 4 4 3 Mitochondrial carrier protein Sporozoite_P67 PF05642.6 GAP89090.1 - 0.009 13.9 0.1 0.024 12.5 0.1 1.3 1 1 0 1 1 1 1 Sporozoite P67 surface antigen Ribosomal_60s PF00428.14 GAP89090.1 - 0.11 12.9 4.4 0.084 13.2 0.7 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Nucleoplasmin PF03066.10 GAP89090.1 - 0.26 10.8 1.3 0.46 9.9 0.1 1.8 2 0 0 2 2 2 0 Nucleoplasmin Chorion_2 PF03964.10 GAP89090.1 - 0.94 10.0 5.1 8.9 6.9 0.7 2.5 2 0 0 2 2 2 0 Chorion family 2 PBP1_TM PF14812.1 GAP89090.1 - 1.3 9.3 7.6 4.1 7.7 2.7 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BAF1_ABF1 PF04684.8 GAP89090.1 - 1.4 7.6 11.2 2 7.1 1.8 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF3245 PF11595.3 GAP89090.1 - 4.1 7.6 11.0 10 6.3 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) DUF4611 PF15387.1 GAP89090.1 - 6.2 7.0 9.7 2.8 8.1 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Sigma70_ner PF04546.8 GAP89090.1 - 8.6 5.9 8.0 16 5.0 2.3 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Urm1 PF09138.6 GAP89091.1 - 8.1e-35 118.8 0.1 9.7e-35 118.5 0.0 1.1 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 GAP89091.1 - 0.013 15.8 0.0 0.019 15.3 0.0 1.3 1 0 0 1 1 1 0 ThiS family Peptidase_A21 PF03566.8 GAP89091.1 - 0.093 10.8 0.2 0.11 10.5 0.2 1.0 1 0 0 1 1 1 0 Peptidase family A21 zf-C2H2 PF00096.21 GAP89092.1 - 2.7e-13 49.3 31.1 0.00066 19.8 0.1 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP89092.1 - 5.2e-09 35.8 31.3 0.0033 17.6 1.0 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAP89092.1 - 9.3e-08 31.9 34.4 0.00053 20.1 2.3 5.0 5 0 0 5 5 5 4 Zinc-finger double domain zf-met PF12874.2 GAP89092.1 - 0.079 13.1 9.9 0.87 9.8 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type TP1 PF02079.11 GAP89092.1 - 1.2 9.0 6.3 0.086 12.6 0.6 2.0 2 0 0 2 2 2 0 Nuclear transition protein 1 RRM_1 PF00076.17 GAP89093.1 - 7.2e-24 83.2 0.2 1.1e-15 56.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP89093.1 - 1.4e-10 40.9 0.1 3.8e-07 30.0 0.0 2.9 2 1 1 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP89093.1 - 2.3e-08 33.7 0.3 6.8e-05 22.6 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CMV_1a_C PF12503.3 GAP89093.1 - 0.11 12.2 0.1 14 5.4 0.0 2.2 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein C terminal MIF4G_like PF09088.6 GAP89094.1 - 3e-79 264.9 0.0 5.2e-79 264.1 0.0 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 GAP89094.1 - 2.9e-49 167.5 0.0 5.4e-49 166.6 0.0 1.5 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 GAP89094.1 - 0.0002 20.8 0.0 0.00038 19.9 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain Pkinase PF00069.20 GAP89095.1 - 7e-64 215.4 0.0 9.2e-64 215.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP89095.1 - 3.2e-25 88.6 0.0 4.2e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP89095.1 - 1.3e-07 30.9 0.0 5.2e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 GAP89095.1 - 0.0013 18.5 0.2 0.0099 15.6 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAP89095.1 - 0.045 13.3 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.6 GAP89095.1 - 0.07 11.9 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 WD40 PF00400.27 GAP89096.1 - 3.8e-48 159.7 3.0 2e-06 27.4 0.0 9.8 9 0 0 9 9 9 7 WD domain, G-beta repeat DUF3317 PF11779.3 GAP89097.1 - 3.3e-19 68.0 2.8 4.1e-19 67.7 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Ion_trans_N PF08412.5 GAP89097.1 - 0.036 13.3 0.6 0.066 12.5 0.2 1.6 2 0 0 2 2 2 0 Ion transport protein N-terminal RF-1 PF00472.15 GAP89098.1 - 1.8e-26 92.1 0.4 2.8e-26 91.5 0.3 1.2 1 0 0 1 1 1 1 RF-1 domain Actin PF00022.14 GAP89099.1 - 7.2e-160 531.7 0.0 8.2e-160 531.5 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 GAP89099.1 - 0.037 14.4 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Fes1 PF08609.5 GAP89100.1 - 6.7e-28 97.0 0.2 3.5e-27 94.7 0.1 2.0 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT PF02985.17 GAP89100.1 - 0.0062 16.5 0.2 0.31 11.2 0.0 2.9 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 GAP89100.1 - 0.013 15.9 0.4 1.6 9.3 0.0 3.1 3 0 0 3 3 3 0 HEAT-like repeat Arm PF00514.18 GAP89100.1 - 0.027 14.2 1.4 5.4 6.9 0.1 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Ribosomal_L5_C PF00673.16 GAP89101.1 - 1.1e-21 76.3 0.0 1.9e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 GAP89101.1 - 0.00037 20.2 0.0 0.00075 19.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 UCH_1 PF13423.1 GAP89102.1 - 4.3e-80 269.3 0.0 9.9e-80 268.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 GAP89102.1 - 3.9e-16 58.9 0.0 9.2e-16 57.7 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HA2 PF04408.18 GAP89104.1 - 9.2e-20 70.5 1.6 9.8e-20 70.4 0.0 1.9 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 GAP89104.1 - 1e-14 54.1 0.1 2.4e-14 52.9 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 GAP89104.1 - 1.7e-14 53.5 0.0 6.1e-14 51.8 0.0 2.0 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 GAP89104.1 - 3e-10 39.8 2.7 1.9e-09 37.2 0.6 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase RWD PF05773.17 GAP89104.1 - 1.7e-08 34.3 0.4 3.9e-08 33.1 0.1 1.8 2 0 0 2 2 2 1 RWD domain AAA_22 PF13401.1 GAP89104.1 - 1.1e-05 25.6 0.4 3.3e-05 24.0 0.2 1.9 2 0 0 2 2 2 1 AAA domain UBA PF00627.26 GAP89104.1 - 0.001 18.8 0.5 0.59 10.0 0.0 3.3 3 0 0 3 3 3 1 UBA/TS-N domain AAA_29 PF13555.1 GAP89104.1 - 0.0039 16.6 0.0 0.0082 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 GAP89104.1 - 0.0046 16.3 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 GAP89104.1 - 0.015 14.3 0.1 0.045 12.8 0.1 1.7 1 0 0 1 1 1 0 KaiC Zot PF05707.7 GAP89104.1 - 0.017 14.5 0.0 0.038 13.4 0.0 1.6 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_23 PF13476.1 GAP89104.1 - 0.046 14.0 1.8 0.073 13.3 0.0 2.2 3 0 0 3 3 1 0 AAA domain AAA_19 PF13245.1 GAP89104.1 - 0.071 12.8 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DND1_DSRM PF14709.1 GAP89104.1 - 0.072 13.3 0.3 0.25 11.6 0.2 2.0 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 ResIII PF04851.10 GAP89104.1 - 0.072 12.9 0.1 0.24 11.2 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit HIT PF01230.18 GAP89105.1 - 6.9e-13 48.9 0.3 3.1e-12 46.8 0.2 1.9 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.3 GAP89105.1 - 2.5e-12 47.0 3.2 5.4e-11 42.7 2.3 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding AT_hook PF02178.14 GAP89106.1 - 8.7e-05 21.7 41.6 0.016 14.8 2.9 5.5 5 0 0 5 5 5 4 AT hook motif BUD22 PF09073.5 GAP89106.1 - 0.032 13.3 11.5 0.042 12.9 8.0 1.1 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.9 GAP89106.1 - 0.13 11.8 5.6 0.22 11.0 3.9 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Daxx PF03344.10 GAP89106.1 - 0.38 9.1 7.3 0.49 8.8 5.1 1.1 1 0 0 1 1 1 0 Daxx Family Cwf_Cwc_15 PF04889.7 GAP89106.1 - 2.2 7.9 7.6 3 7.4 5.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 GAP89106.1 - 4.3 5.1 7.2 5 4.9 5.0 1.1 1 0 0 1 1 1 0 Nop14-like family MSP1_C PF07462.6 GAP89106.1 - 4.4 5.5 5.0 5.6 5.2 3.4 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Mucin PF01456.12 GAP89106.1 - 5.2 6.8 14.9 2.4 7.9 1.6 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein TRAP_alpha PF03896.11 GAP89107.1 - 1.5e-06 27.4 0.0 2.6e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit PepX_C PF08530.5 GAP89108.1 - 2.8e-43 148.3 0.1 4e-43 147.8 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.13 GAP89108.1 - 2.9e-21 76.1 0.0 6.7e-21 74.9 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 GAP89108.1 - 0.0059 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase IN_DBD_C PF00552.16 GAP89108.1 - 0.031 13.7 0.0 0.07 12.5 0.0 1.6 1 0 0 1 1 1 0 Integrase DNA binding domain Sulfatase PF00884.18 GAP89109.1 - 7.9e-65 219.0 0.5 9.9e-65 218.7 0.3 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 GAP89109.1 - 3.1e-07 30.0 0.3 0.0013 18.1 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 GAP89109.1 - 0.028 12.8 0.0 2.1 6.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF229) DUF1501 PF07394.7 GAP89109.1 - 0.14 10.9 0.0 0.26 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Med5 PF08689.5 GAP89110.1 - 2e-242 807.0 0.0 2.7e-242 806.6 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 DUF2593 PF10767.4 GAP89110.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2593) NADH-u_ox-rdase PF10785.4 GAP89111.1 - 0.16 12.2 0.1 7.8 6.8 0.0 2.5 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit HET PF06985.6 GAP89113.1 - 1.2e-20 74.1 9.3 5.7e-19 68.6 6.5 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) EphA2_TM PF14575.1 GAP89114.1 - 0.0093 16.3 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.5 GAP89114.1 - 0.024 13.9 0.2 0.049 12.9 0.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF1191 PF06697.7 GAP89114.1 - 0.091 11.5 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Shisa PF13908.1 GAP89114.1 - 0.19 11.8 10.0 5.4 7.1 4.9 2.6 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF4202 PF13875.1 GAP89115.1 - 4.2e-70 235.1 0.0 4.9e-70 234.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) FMN_dh PF01070.13 GAP89116.1 - 9.4e-110 366.7 0.0 1.8e-109 365.9 0.0 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 GAP89116.1 - 6.7e-17 61.0 0.0 1.3e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 GAP89116.1 - 2.5e-05 23.3 1.4 7.5e-05 21.8 0.1 2.2 2 1 1 3 3 3 1 Conserved region in glutamate synthase IMPDH PF00478.20 GAP89116.1 - 0.002 17.1 4.1 0.0065 15.3 0.2 2.4 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 GAP89116.1 - 0.007 15.5 0.1 0.011 14.8 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 GAP89116.1 - 0.019 14.0 0.1 0.39 9.7 0.0 2.1 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG RESP18 PF14948.1 GAP89117.1 - 1.7 8.7 5.8 0.68 10.0 1.6 2.1 1 1 0 2 2 2 0 RESP18 domain Heme_oxygenase PF01126.15 GAP89118.1 - 2.4e-15 56.6 0.0 3.1e-14 53.0 0.0 2.1 2 0 0 2 2 2 1 Heme oxygenase EthD PF07110.6 GAP89119.1 - 0.00081 20.2 0.0 0.0018 19.2 0.0 1.6 1 0 0 1 1 1 1 EthD domain EamA PF00892.15 GAP89120.1 - 4.9e-06 26.6 10.7 5.6e-06 26.4 7.5 1.0 1 0 0 1 1 1 1 EamA-like transporter family TPT PF03151.11 GAP89120.1 - 0.073 12.7 7.8 0.098 12.3 5.4 1.1 1 0 0 1 1 1 0 Triose-phosphate Transporter family Ras PF00071.17 GAP89121.1 - 9.9e-57 190.8 0.1 1.2e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAP89121.1 - 1.9e-18 67.1 0.0 2.9e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAP89121.1 - 2.4e-13 49.7 0.0 2.8e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAP89121.1 - 4.9e-08 32.9 0.0 6.8e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 GAP89121.1 - 7.9e-08 31.7 0.0 9.9e-08 31.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAP89121.1 - 4.4e-07 29.5 0.0 8.4e-06 25.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 GAP89121.1 - 0.00072 19.7 0.0 0.001 19.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 GAP89121.1 - 0.001 18.2 0.1 0.0019 17.4 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_5 PF07728.9 GAP89121.1 - 0.0012 18.5 0.0 0.0047 16.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) SRPRB PF09439.5 GAP89121.1 - 0.002 17.4 0.0 0.0024 17.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 GAP89121.1 - 0.0035 17.3 0.0 0.011 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.12 GAP89121.1 - 0.0038 16.8 0.2 0.14 11.6 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 GAP89121.1 - 0.0044 16.6 0.1 0.0077 15.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 GAP89121.1 - 0.0047 16.6 0.1 0.0095 15.6 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase AAA_10 PF12846.2 GAP89121.1 - 0.0065 15.9 0.1 0.012 15.1 0.1 1.5 1 1 0 1 1 1 1 AAA-like domain PduV-EutP PF10662.4 GAP89121.1 - 0.011 15.2 0.0 0.1 12.1 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 GAP89121.1 - 0.012 14.6 0.1 0.032 13.2 0.0 1.8 2 0 0 2 2 2 0 Septin MobB PF03205.9 GAP89121.1 - 0.021 14.5 0.1 0.056 13.1 0.0 1.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 GAP89121.1 - 0.023 14.3 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 NTPase cobW PF02492.14 GAP89121.1 - 0.037 13.4 0.0 0.11 11.8 0.0 1.7 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 GAP89121.1 - 0.054 13.6 0.1 0.26 11.4 0.1 2.1 1 1 0 1 1 1 0 RNA helicase NACHT PF05729.7 GAP89121.1 - 0.084 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Borrelia_P83 PF05262.6 GAP89122.1 - 0.071 11.3 1.7 0.089 11.0 1.2 1.3 1 1 0 1 1 1 0 Borrelia P83/100 protein AAA_3 PF07726.6 GAP89123.1 - 0.0022 17.6 0.1 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GDA1_CD39 PF01150.12 GAP89124.1 - 1.6e-96 323.5 0.0 2.2e-96 323.0 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family PUL PF08324.6 GAP89125.1 - 9.7e-43 145.8 0.0 1.4e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.9 GAP89125.1 - 2.6e-34 118.1 0.0 4.6e-34 117.3 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 GAP89125.1 - 5.1e-16 58.2 0.0 1.1e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.1 GAP89125.1 - 3.7e-07 29.8 0.0 1.5e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.1 GAP89125.1 - 0.00013 22.1 0.1 0.00071 19.7 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 GAP89125.1 - 0.0015 18.2 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_4 PF13462.1 GAP89125.1 - 0.0097 15.9 0.1 0.065 13.2 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin IBN_N PF03810.14 GAP89125.1 - 0.012 15.4 0.3 0.025 14.4 0.2 1.5 1 0 0 1 1 1 0 Importin-beta N-terminal domain Thioredoxin_8 PF13905.1 GAP89125.1 - 0.014 15.5 0.0 0.22 11.6 0.0 2.3 1 1 1 2 2 2 0 Thioredoxin-like AhpC-TSA PF00578.16 GAP89125.1 - 0.02 14.5 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.5 GAP89125.1 - 0.077 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Redoxin Thioredoxin_7 PF13899.1 GAP89125.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Kinesin PF00225.18 GAP89126.1 - 2e-113 378.4 0.0 3.5e-113 377.6 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain VSG_B PF13206.1 GAP89126.1 - 0.13 11.3 5.4 0.26 10.3 3.7 1.4 1 0 0 1 1 1 0 Trypanosomal VSG domain Cupin_8 PF13621.1 GAP89127.1 - 2.7e-64 217.0 0.0 3.4e-64 216.7 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 GAP89127.1 - 1.1e-06 28.0 0.2 0.0011 18.3 0.0 2.4 2 1 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 GAP89127.1 - 0.02 15.1 0.1 0.62 10.3 0.0 2.7 3 0 0 3 3 3 0 JmjC domain, hydroxylase Sterol-sensing PF12349.3 GAP89129.1 - 1.4e-35 122.0 10.0 1.9e-35 121.5 6.1 1.9 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 GAP89129.1 - 3.5e-09 35.1 8.9 3.5e-09 35.1 6.1 1.6 2 0 0 2 2 2 1 Patched family DUF2244 PF10003.4 GAP89129.1 - 1.1 8.6 4.8 12 5.2 0.5 2.7 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) 14-3-3 PF00244.15 GAP89130.1 - 4.3e-08 32.5 0.0 9.6e-08 31.3 0.0 1.4 2 0 0 2 2 2 1 14-3-3 protein WD40 PF00400.27 GAP89131.1 - 2.2e-20 71.7 7.0 1.4e-05 24.7 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 GAP89131.1 - 1.9e-05 23.0 0.0 4.5e-05 21.7 0.0 1.5 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Spb1_C PF07780.7 GAP89132.1 - 2.9e-75 252.4 27.4 2.9e-75 252.4 19.0 3.6 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.14 GAP89132.1 - 2.5e-54 184.0 0.1 6.6e-54 182.6 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.3 GAP89132.1 - 8.8e-49 165.0 7.6 8.8e-49 165.0 5.3 4.8 4 2 0 4 4 4 1 Domain of unknown function (DUF3381) Ebp2 PF05890.7 GAP89133.1 - 1e-87 293.8 13.4 1e-87 293.8 9.3 2.4 2 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Ebola_NP PF05505.7 GAP89133.1 - 4 5.3 18.3 6.3 4.7 12.7 1.3 1 0 0 1 1 1 0 Ebola nucleoprotein Ank_2 PF12796.2 GAP89134.1 - 1e-115 378.2 35.2 1.1e-18 67.3 0.1 7.3 2 2 10 12 12 12 11 Ankyrin repeats (3 copies) Ank PF00023.25 GAP89134.1 - 9e-57 186.1 20.1 2.8e-07 29.9 0.0 14.9 15 0 0 15 15 15 9 Ankyrin repeat Ank_3 PF13606.1 GAP89134.1 - 1.6e-43 142.3 4.4 6.9e-05 22.7 0.0 12.9 13 0 0 13 13 13 7 Ankyrin repeat Ank_4 PF13637.1 GAP89134.1 - 3e-42 142.2 4.1 4.6e-08 33.3 0.0 10.4 4 3 6 11 11 11 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP89134.1 - 2.2e-36 123.0 12.0 6.9e-06 26.1 0.2 11.2 3 3 8 12 12 12 6 Ankyrin repeats (many copies) Abhydrolase_5 PF12695.2 GAP89134.1 - 3.8e-07 29.9 0.0 1.6e-06 27.9 0.0 2.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP89134.1 - 3e-05 24.0 0.0 8.6e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAP89134.1 - 3.7e-05 23.4 0.0 0.00011 21.8 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 GAP89134.1 - 0.00012 21.5 0.0 0.00025 20.4 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 GAP89134.1 - 0.021 14.4 0.0 0.072 12.7 0.0 1.9 1 0 0 1 1 1 0 Lipase (class 3) AAA_22 PF13401.1 GAP89134.1 - 0.056 13.5 0.0 0.056 13.5 0.0 2.4 2 0 0 2 2 1 0 AAA domain Med15 PF09606.5 GAP89134.1 - 1.1 7.4 63.5 1.7 6.7 44.0 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Hce2 PF14856.1 GAP89136.1 - 1.4e-05 24.9 0.0 1.7e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Cyanate_lyase PF02560.9 GAP89137.1 - 2.9e-31 106.8 0.0 4.2e-31 106.2 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain Sigma70_r4_2 PF08281.7 GAP89137.1 - 0.002 17.5 0.0 0.0042 16.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_3 PF01381.17 GAP89137.1 - 0.017 14.9 0.1 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix HTH_31 PF13560.1 GAP89137.1 - 0.051 13.7 0.2 0.089 13.0 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain TetR_N PF00440.18 GAP89137.1 - 0.053 13.1 0.5 0.16 11.6 0.3 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family NAD_kinase PF01513.16 GAP89138.1 - 1.6e-67 227.2 0.0 2.3e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Abhydrolase_4 PF08386.5 GAP89140.1 - 2.1e-17 62.8 0.0 7.5e-17 61.1 0.0 1.9 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 GAP89140.1 - 8e-14 51.7 0.0 6.4e-07 29.1 0.0 3.3 3 0 0 3 3 3 3 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAP89140.1 - 2.2e-10 40.8 0.0 4.3e-09 36.5 0.0 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP89140.1 - 0.008 15.9 0.0 4 7.1 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family GTP_EFTU PF00009.22 GAP89141.1 - 7.4e-59 198.3 0.2 9.8e-59 197.9 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 GAP89141.1 - 4e-25 87.8 0.1 2.6e-24 85.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 GAP89141.1 - 5.3e-17 61.7 2.6 5.3e-17 61.7 1.8 2.3 2 1 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAP89141.1 - 5.6e-05 23.0 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAP89141.1 - 0.0011 19.4 0.0 0.002 18.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D4 PF14578.1 GAP89141.1 - 0.0017 17.9 0.3 0.0052 16.3 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 PduV-EutP PF10662.4 GAP89141.1 - 0.037 13.5 0.2 9.9 5.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DisA_N PF02457.11 GAP89141.1 - 0.07 12.2 0.1 0.63 9.1 0.0 2.2 2 0 0 2 2 2 0 DisA bacterial checkpoint controller nucleotide-binding cobW PF02492.14 GAP89141.1 - 0.11 11.9 0.4 0.34 10.3 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Thioredoxin PF00085.15 GAP89142.1 - 7.9e-63 208.6 0.1 6.8e-31 106.0 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 GAP89142.1 - 1.7e-22 79.8 2.5 1.9e-22 79.6 0.2 2.2 3 0 0 3 3 3 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 GAP89142.1 - 4.9e-19 68.5 0.0 6.1e-08 32.8 0.0 3.2 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 GAP89142.1 - 5.6e-13 48.8 0.0 0.00026 21.0 0.0 3.3 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 GAP89142.1 - 6.3e-13 48.5 0.0 1.4e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.1 GAP89142.1 - 8.1e-07 28.6 0.1 0.00038 20.0 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin AhpC-TSA PF00578.16 GAP89142.1 - 1e-06 28.4 0.1 0.0083 15.8 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_6 PF13848.1 GAP89142.1 - 2.7e-06 27.3 0.0 0.024 14.4 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like domain Redoxin PF08534.5 GAP89142.1 - 3.8e-06 26.5 0.5 0.0043 16.6 0.0 2.4 2 0 0 2 2 2 2 Redoxin Thioredoxin_4 PF13462.1 GAP89142.1 - 1.7e-05 24.9 0.6 0.094 12.7 0.0 3.7 3 2 2 5 5 5 2 Thioredoxin ERp29_N PF07912.8 GAP89142.1 - 6.3e-05 22.9 0.1 0.063 13.2 0.0 2.7 2 1 0 2 2 2 2 ERp29, N-terminal domain HyaE PF07449.6 GAP89142.1 - 0.00055 19.8 0.0 0.07 13.0 0.0 3.0 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.19 GAP89142.1 - 0.0053 16.7 0.1 3.2 7.7 0.0 3.0 2 1 0 2 2 2 1 Glutaredoxin zf-rbx1 PF12678.2 GAP89143.1 - 2e-09 37.3 0.5 4.2e-09 36.3 0.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 GAP89143.1 - 9.6e-08 31.7 8.2 5.7e-07 29.2 5.7 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 GAP89143.1 - 4.7e-07 29.3 0.3 7.9e-07 28.6 0.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAP89143.1 - 2.4e-06 27.1 2.6 7.6e-06 25.5 1.9 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 GAP89143.1 - 6.9e-05 22.4 5.0 0.00034 20.2 3.5 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAP89143.1 - 0.00023 21.1 2.4 0.00023 21.1 1.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Tetraspannin PF00335.15 GAP89143.1 - 0.0083 15.4 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 1 Tetraspanin family zf-Apc11 PF12861.2 GAP89143.1 - 0.018 14.9 1.2 0.046 13.5 0.8 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PQ-loop PF04193.9 GAP89143.1 - 0.034 13.6 1.8 0.12 11.9 1.3 1.9 1 0 0 1 1 1 0 PQ loop repeat zf-RING_UBOX PF13445.1 GAP89143.1 - 0.14 11.8 4.8 0.078 12.7 0.6 2.4 2 1 0 2 2 2 0 RING-type zinc-finger DUF2921 PF11145.3 GAP89143.1 - 0.26 8.9 0.3 0.37 8.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) FANCL_C PF11793.3 GAP89143.1 - 5 7.1 5.3 2.8 7.9 1.8 2.0 2 1 0 2 2 2 0 FANCL C-terminal domain NAD_binding_6 PF08030.7 GAP89144.1 - 0.27 11.1 1.2 0.47 10.3 0.8 1.5 1 1 0 1 1 1 0 Ferric reductase NAD binding domain Fungal_trans PF04082.13 GAP89145.1 - 1.4e-12 47.0 0.0 2.3e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Med3 PF11593.3 GAP89145.1 - 0.13 11.5 4.3 0.21 10.8 3.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Lactamase_B PF00753.22 GAP89146.1 - 1.8e-27 96.2 4.1 6.6e-27 94.4 2.8 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAP89146.1 - 2.9e-05 23.7 0.1 5.3e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.15 GAP89146.1 - 0.0026 17.0 0.0 0.0055 16.0 0.0 1.4 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family LVIVD PF08309.6 GAP89146.1 - 0.057 12.4 1.1 0.21 10.6 0.2 2.1 2 0 0 2 2 2 0 LVIVD repeat DUF1236 PF06823.7 GAP89146.1 - 0.083 12.6 0.0 0.75 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1236) Peripla_BP_4 PF13407.1 GAP89146.1 - 0.13 11.6 2.1 0.37 10.1 0.5 2.0 2 0 0 2 2 2 0 Periplasmic binding protein domain Las1 PF04031.8 GAP89147.1 - 3.2e-60 202.2 0.2 4.6e-60 201.7 0.1 1.2 1 0 0 1 1 1 1 Las1-like HR1 PF02185.11 GAP89147.1 - 0.058 13.1 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 Hr1 repeat SKG6 PF08693.5 GAP89151.1 - 0.045 13.0 0.2 0.097 11.9 0.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MFS_1 PF07690.11 GAP89152.1 - 4.1e-21 75.0 48.0 3.6e-13 48.9 15.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 GAP89152.1 - 0.029 14.3 7.9 1.7 8.7 0.0 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) Hid1 PF12722.2 GAP89153.1 - 4.5e-259 861.8 0.0 2.6e-258 859.3 0.0 1.8 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 GAP89153.1 - 7.7e-82 275.4 0.0 1.1e-81 274.9 0.0 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Cation_efflux PF01545.16 GAP89154.1 - 2e-30 105.8 8.0 2.9e-30 105.3 5.5 1.2 1 0 0 1 1 1 1 Cation efflux family DUF805 PF05656.9 GAP89155.1 - 3.7 7.4 7.4 10 5.9 5.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF805) zf-MYND PF01753.13 GAP89156.1 - 6.8e-08 32.2 19.6 2e-07 30.7 13.6 1.9 1 0 0 1 1 1 1 MYND finger Zip PF02535.17 GAP89156.1 - 0.032 13.2 6.1 0.05 12.6 4.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Innate_immun PF12782.2 GAP89156.1 - 3.9 6.5 13.5 0.079 12.1 2.4 2.2 2 0 0 2 2 2 0 Invertebrate innate immunity transcript family SelP_N PF04592.9 GAP89156.1 - 9.2 5.5 15.7 4.3 6.6 6.6 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region IF4E PF01652.13 GAP89157.1 - 8.7e-39 132.6 0.0 1.1e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E EF-hand_6 PF13405.1 GAP89158.1 - 0.0074 16.0 2.2 5.2 7.2 0.2 4.1 4 1 1 5 5 5 2 EF-hand domain EF-hand_9 PF14658.1 GAP89158.1 - 0.13 12.2 0.0 0.66 9.9 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain Zn_clus PF00172.13 GAP89159.1 - 1.3e-08 34.5 7.8 2.9e-08 33.4 5.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mid1 PF12929.2 GAP89160.1 - 3.1e-107 358.9 6.2 4.4e-107 358.4 4.3 1.2 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component RAMP4 PF06624.7 GAP89161.1 - 8.4e-07 28.4 0.0 1.1e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF1206 PF06724.6 GAP89161.1 - 0.0086 15.8 0.0 0.0095 15.6 0.0 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1206) SMAP PF15477.1 GAP89162.1 - 4.3e-19 68.5 4.2 4.3e-19 68.5 2.9 5.3 4 2 1 5 5 5 1 Small acidic protein family Sec10 PF07393.6 GAP89163.1 - 2.5e-164 548.2 0.0 3.2e-164 547.9 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.28 GAP89163.1 - 5.3e-06 25.9 0.0 1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAP89163.1 - 8.2e-06 25.4 0.0 2.1e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like bZIP_2 PF07716.10 GAP89164.1 - 0.011 15.5 11.6 0.02 14.7 8.0 1.5 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.16 GAP89164.1 - 0.012 15.4 9.4 0.012 15.4 6.5 1.5 1 1 0 1 1 1 0 bZIP transcription factor Milton PF12448.3 GAP89164.1 - 0.016 15.3 2.1 0.016 15.3 1.5 1.7 2 0 0 2 2 2 0 Kinesin associated protein bZIP_Maf PF03131.12 GAP89164.1 - 2.8 8.2 10.8 1.5 9.1 5.9 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor SNF2_N PF00176.18 GAP89165.1 - 5e-54 183.1 0.0 8.2e-54 182.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.1 GAP89165.1 - 2.8e-09 36.8 14.2 6.2e-09 35.7 9.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAP89165.1 - 8.4e-08 31.9 12.1 2.2e-07 30.5 8.4 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 GAP89165.1 - 2.1e-07 30.4 12.4 4.8e-07 29.3 8.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAP89165.1 - 8.6e-07 28.5 9.7 1.9e-06 27.4 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAP89165.1 - 3.5e-06 26.6 11.3 7.7e-06 25.5 7.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 GAP89165.1 - 2.5e-05 24.3 6.5 6.4e-05 22.9 4.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 GAP89165.1 - 0.0017 18.1 9.1 0.0072 16.1 6.3 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 GAP89165.1 - 0.0024 17.5 11.4 0.014 15.1 2.7 2.8 2 0 0 2 2 2 2 RING-type zinc-finger zf-Apc11 PF12861.2 GAP89165.1 - 0.019 14.8 4.9 0.043 13.6 3.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger HDV_ag PF01517.13 GAP89165.1 - 0.046 13.3 0.5 0.11 12.1 0.0 1.8 2 0 0 2 2 1 0 Hepatitis delta virus delta antigen Helicase_C PF00271.26 GAP89165.1 - 0.048 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Helicase conserved C-terminal domain zf-RING_4 PF14570.1 GAP89165.1 - 0.19 11.3 11.5 0.48 10.0 8.0 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 GAP89165.1 - 0.39 10.2 5.3 0.95 9.0 3.7 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 GAP89165.1 - 0.54 10.0 4.5 1.4 8.7 3.1 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein IGR PF09597.5 GAP89166.1 - 1.5e-06 27.9 0.0 2.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 IGR protein motif Pkinase PF00069.20 GAP89167.1 - 3.5e-66 223.0 0.0 4.2e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP89167.1 - 1.9e-35 122.1 0.0 2.9e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP89167.1 - 0.00035 19.6 0.0 0.0006 18.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Frag1 PF10277.4 GAP89168.1 - 6.4e-40 136.9 12.5 7.5e-40 136.7 8.7 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF1282 PF06930.7 GAP89168.1 - 3.8 7.1 9.0 0.55 9.8 0.1 2.6 1 1 1 3 3 3 0 Protein of unknown function (DUF1282) BioY PF02632.9 GAP89168.1 - 9.1 5.9 10.4 4.4 6.9 5.2 2.0 2 1 0 2 2 2 0 BioY family DUF3812 PF12757.2 GAP89169.1 - 3e-31 108.0 9.6 3e-31 108.0 6.7 4.6 4 1 1 5 5 5 1 Protein of unknown function (DUF3812) Y_phosphatase3 PF13350.1 GAP89170.1 - 2.4e-29 102.6 0.2 1.4e-15 57.9 0.0 2.1 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 GAP89170.1 - 0.00044 19.6 0.0 0.0089 15.4 0.0 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 GAP89170.1 - 0.00046 20.2 0.0 0.0012 18.9 0.0 1.8 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 GAP89170.1 - 0.00066 19.0 0.0 0.00098 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.9 GAP89170.1 - 0.019 13.7 0.0 0.045 12.5 0.0 1.5 2 0 0 2 2 2 0 Myotubularin-like phosphatase domain DSPc PF00782.15 GAP89170.1 - 0.048 13.2 0.0 0.36 10.4 0.0 2.0 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Hairy_orange PF07527.8 GAP89170.1 - 0.097 12.4 0.2 7.4 6.3 0.1 3.2 2 1 0 2 2 2 0 Hairy Orange Methyltransf_12 PF08242.7 GAP89171.1 - 4.9e-14 52.6 0.0 1e-13 51.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP89171.1 - 8.8e-12 45.3 0.0 1.7e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP89171.1 - 9.2e-12 45.2 0.0 2.1e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP89171.1 - 1.7e-11 44.1 0.0 3.5e-11 43.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP89171.1 - 6.3e-10 38.8 0.0 9.6e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP89171.1 - 1.5e-09 38.3 0.0 3.2e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP89171.1 - 6e-08 32.0 0.0 9.8e-08 31.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 GAP89171.1 - 9.3e-06 25.6 0.0 2.6e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAP89171.1 - 5.4e-05 22.6 0.0 9.6e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.12 GAP89171.1 - 0.0031 16.5 0.0 0.7 8.8 0.0 2.3 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family DUF3419 PF11899.3 GAP89171.1 - 0.0041 15.8 0.0 0.0058 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_24 PF13578.1 GAP89171.1 - 0.0059 17.4 0.0 0.014 16.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 GAP89171.1 - 0.011 15.1 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase FmrO PF07091.6 GAP89171.1 - 0.038 12.9 0.0 0.061 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Polyketide_cyc PF03364.15 GAP89172.1 - 5.2e-21 74.9 0.0 2.8e-20 72.6 0.0 1.9 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport TPR_19 PF14559.1 GAP89174.1 - 8.7e-13 48.4 2.2 4.7e-07 30.0 0.3 4.5 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAP89174.1 - 3.2e-11 43.5 9.1 4.2e-06 27.2 0.5 3.6 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 GAP89174.1 - 4.4e-11 42.2 7.0 2.3e-07 30.3 1.1 4.2 3 2 1 4 4 4 2 TPR repeat TPR_2 PF07719.12 GAP89174.1 - 1.1e-09 37.3 1.9 0.0005 19.7 0.9 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAP89174.1 - 2.4e-09 36.9 4.3 1.6e-05 24.7 0.9 3.7 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 GAP89174.1 - 2.8e-09 36.7 4.6 2.7e-05 24.3 0.2 4.5 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAP89174.1 - 1.5e-07 31.0 1.1 0.0028 17.7 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAP89174.1 - 8.9e-06 25.8 2.0 5.6 7.6 0.0 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAP89174.1 - 1.4e-05 24.5 0.3 0.011 15.3 0.5 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 GAP89174.1 - 4e-05 23.6 5.2 0.057 13.5 0.2 4.7 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAP89174.1 - 7.7e-05 22.4 1.6 0.014 15.2 0.2 3.2 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAP89174.1 - 7.9e-05 22.1 0.2 0.085 12.6 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 GAP89174.1 - 0.011 15.8 0.1 0.039 14.0 0.1 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 GAP89174.1 - 0.026 14.3 0.9 2.5 8.1 0.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_19 PF13245.1 GAP89174.1 - 0.077 12.7 0.2 16 5.3 0.0 2.9 1 1 1 2 2 2 0 Part of AAA domain ChAPs PF09295.5 GAP89174.1 - 0.093 11.4 0.1 0.12 11.0 0.1 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) GRIP PF01465.15 GAP89174.1 - 0.11 12.0 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 GRIP domain BTAD PF03704.12 GAP89174.1 - 0.28 11.4 6.4 1.6 8.9 0.2 3.4 3 1 1 4 4 4 0 Bacterial transcriptional activator domain Adaptin_N PF01602.15 GAP89175.1 - 1.6e-81 274.2 0.0 3.2e-81 273.2 0.0 1.5 1 1 0 1 1 1 1 Adaptin N terminal region HDPD PF02924.9 GAP89175.1 - 0.033 13.9 0.2 0.09 12.5 0.2 1.7 1 0 0 1 1 1 0 Bacteriophage lambda head decoration protein D FCH PF00611.18 GAP89176.1 - 3.9e-16 58.9 0.0 1.5e-15 57.1 0.0 2.1 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.22 GAP89176.1 - 1.6e-15 56.9 0.4 5.4e-15 55.3 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.16 GAP89176.1 - 3.3e-14 52.3 0.0 7.4e-14 51.2 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Med4 PF10018.4 GAP89176.1 - 0.79 9.0 6.2 0.68 9.3 0.0 2.9 2 1 1 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 DOT1 PF08123.8 GAP89177.1 - 4.5e-73 244.9 0.1 8.2e-73 244.0 0.1 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 GAP89177.1 - 1.6e-05 24.9 0.0 3.7e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP89177.1 - 0.00033 20.2 1.3 0.00066 19.2 0.3 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP89177.1 - 0.0017 18.8 0.2 0.0052 17.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain ATG16 PF08614.6 GAP89178.1 - 1.5e-43 148.8 2.3 1.8e-43 148.6 1.6 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Mnd1 PF03962.10 GAP89178.1 - 0.00061 19.5 5.1 0.0045 16.6 2.2 2.0 2 0 0 2 2 2 1 Mnd1 family Metal_resist PF13801.1 GAP89178.1 - 0.0022 17.9 3.7 0.0022 17.9 2.6 1.9 2 0 0 2 2 2 1 Heavy-metal resistance Seryl_tRNA_N PF02403.17 GAP89178.1 - 0.0074 16.2 3.8 0.0074 16.2 2.6 2.7 2 1 1 3 3 3 1 Seryl-tRNA synthetase N-terminal domain Nup54 PF13874.1 GAP89178.1 - 0.0074 15.9 2.6 0.0074 15.9 1.8 2.6 2 1 1 3 3 3 1 Nucleoporin complex subunit 54 Rho_Binding PF08912.6 GAP89178.1 - 0.11 12.7 7.5 0.08 13.2 3.4 2.0 2 0 0 2 2 2 0 Rho Binding IlvC PF01450.14 GAP89178.1 - 0.16 11.9 0.8 0.3 10.9 0.6 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain GAS PF13851.1 GAP89178.1 - 0.16 11.1 9.9 0.14 11.3 0.5 2.6 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Cep57_CLD_2 PF14197.1 GAP89178.1 - 0.5 10.3 18.5 0.17 11.8 2.7 3.6 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 IncA PF04156.9 GAP89178.1 - 0.55 9.8 7.7 0.79 9.2 3.7 2.1 2 1 0 2 2 2 0 IncA protein V_ATPase_I PF01496.14 GAP89178.1 - 1.1 7.0 3.1 1.3 6.7 2.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 GAP89178.1 - 1.1 8.1 10.7 0.22 10.4 5.2 1.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Uds1 PF15456.1 GAP89178.1 - 2.4 8.1 8.1 0.19 11.7 1.9 1.9 2 1 0 2 2 2 0 Up-regulated During Septation DUF2205 PF10224.4 GAP89178.1 - 2.5 7.7 8.0 18 5.0 1.8 3.1 2 1 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) DUF972 PF06156.8 GAP89178.1 - 4.2 7.7 6.4 4.2 7.7 2.9 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DivIVA PF05103.8 GAP89178.1 - 5.6 7.0 11.1 1.3 9.0 3.5 2.5 2 1 1 3 3 3 0 DivIVA protein APG6 PF04111.7 GAP89178.1 - 8.1 5.3 9.7 2.1 7.2 4.3 1.8 2 0 0 2 2 2 0 Autophagy protein Apg6 Fork_head PF00250.13 GAP89179.1 - 1.1e-34 118.3 0.2 2e-34 117.4 0.1 1.4 1 0 0 1 1 1 1 Fork head domain DUF1649 PF07855.7 GAP89180.1 - 2.1e-59 199.8 0.0 2.5e-59 199.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) PH PF00169.24 GAP89181.1 - 4.4e-25 87.8 0.3 3.4e-14 52.9 0.0 2.2 2 0 0 2 2 2 2 PH domain PH_9 PF15410.1 GAP89181.1 - 4.3e-11 43.0 0.7 5.5e-05 23.3 0.2 3.3 2 1 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.1 GAP89181.1 - 1.6e-08 34.8 5.2 4e-05 23.8 0.0 3.8 2 2 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.1 GAP89181.1 - 0.0023 17.7 0.1 0.024 14.5 0.1 2.4 2 1 0 2 2 2 1 PH domain PH_8 PF15409.1 GAP89181.1 - 0.0037 17.3 0.0 0.0078 16.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Cellulase PF00150.13 GAP89182.1 - 2.9e-18 66.0 2.1 7.1e-18 64.8 1.5 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PAT1 PF09770.4 GAP89183.1 - 2.3 6.3 18.2 3 5.9 12.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RRM_1 PF00076.17 GAP89184.1 - 1e-60 201.2 0.0 2.8e-21 74.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP89184.1 - 1.2e-44 150.1 0.0 8.4e-15 54.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP89184.1 - 4.7e-32 109.6 0.0 5.7e-11 42.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAP89184.1 - 1.2e-08 34.5 0.0 0.0052 16.5 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 GAP89184.1 - 0.00063 19.6 0.0 0.94 9.4 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_3 PF08777.6 GAP89184.1 - 0.13 12.1 0.0 2.2 8.1 0.0 2.4 3 0 0 3 3 3 0 RNA binding motif Pkinase PF00069.20 GAP89185.1 - 1.1e-52 178.7 0.0 2.2e-52 177.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP89185.1 - 1.4e-23 83.3 0.0 3.2e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAP89185.1 - 0.0001 22.1 2.9 0.00049 19.8 0.1 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 GAP89185.1 - 0.002 17.4 0.4 0.0057 16.0 0.2 1.6 1 1 0 1 1 1 1 RIO1 family DUF4430 PF14478.1 GAP89185.1 - 0.034 14.2 1.3 0.15 12.1 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4430) RRM_1 PF00076.17 GAP89186.1 - 6.6e-05 22.4 0.0 0.00014 21.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP89186.1 - 0.0005 19.8 0.0 0.0026 17.5 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP89186.1 - 0.0026 17.6 0.0 0.0048 16.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.5 GAP89186.1 - 0.051 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding Ribosomal_L2_C PF03947.13 GAP89187.1 - 8.3e-39 132.3 3.4 1.3e-38 131.6 2.4 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 GAP89187.1 - 3.1e-13 49.4 0.1 6.3e-13 48.5 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PfkB PF00294.19 GAP89188.1 - 1.8e-63 214.5 0.3 2e-63 214.3 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 GAP89188.1 - 0.039 13.1 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase EST1_DNA_bind PF10373.4 GAP89189.1 - 5e-46 157.1 2.6 5e-46 157.1 1.8 1.7 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.4 GAP89189.1 - 9.2e-19 67.7 0.8 9.2e-19 67.7 0.5 2.2 2 0 0 2 2 2 1 Telomerase activating protein Est1 TPR_11 PF13414.1 GAP89189.1 - 0.012 15.2 0.1 0.026 14.1 0.1 1.5 1 0 0 1 1 1 0 TPR repeat G10 PF01125.12 GAP89191.1 - 1.3e-59 199.9 2.7 1.4e-59 199.7 1.9 1.0 1 0 0 1 1 1 1 G10 protein Tmpp129 PF10272.4 GAP89191.1 - 8.1 5.0 11.3 12 4.5 7.8 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor Complex1_LYR PF05347.10 GAP89192.1 - 1e-06 28.4 0.2 2e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAP89192.1 - 2e-05 24.6 0.2 4.4e-05 23.6 0.1 1.7 1 1 1 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 GAP89192.1 - 0.006 17.0 0.1 0.0079 16.6 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like RNA_pol_L_2 PF13656.1 GAP89193.1 - 8.7e-29 98.7 0.0 1.1e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 GAP89193.1 - 7.2e-12 44.2 0.0 8.9e-12 43.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF3987 PF13148.1 GAP89193.1 - 0.11 11.1 0.3 0.16 10.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Pkinase PF00069.20 GAP89195.1 - 7.8e-64 215.3 0.0 1e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP89195.1 - 3.7e-26 91.7 0.0 5.1e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP89195.1 - 0.036 13.0 0.0 0.081 11.8 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 GAP89195.1 - 0.077 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3484 PF11983.3 GAP89195.1 - 0.13 13.1 1.2 4.2 8.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3484) Pkinase PF00069.20 GAP89196.1 - 8.3e-60 202.1 0.0 1.7e-59 201.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP89196.1 - 1.4e-34 119.3 0.0 1.9e-32 112.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAP89196.1 - 2.4e-10 39.8 0.0 7.8e-10 38.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 GAP89196.1 - 0.00011 22.0 0.1 0.00023 21.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Sybindin PF04099.7 GAP89197.1 - 1.9e-23 82.7 0.0 2.6e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Mucin PF01456.12 GAP89197.1 - 0.22 11.3 14.4 0.3 10.8 10.0 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein MSP1_C PF07462.6 GAP89197.1 - 1.8 6.8 3.5 2.3 6.4 2.4 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Med3 PF11593.3 GAP89197.1 - 3.1 6.9 16.9 4.2 6.5 11.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Peroxin-3 PF04882.7 GAP89198.1 - 1.8e-140 468.4 0.0 2.1e-140 468.2 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 WD40 PF00400.27 GAP89199.1 - 3.1e-16 58.5 0.4 0.0019 18.0 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat Enamelin PF15362.1 GAP89199.1 - 0.0065 14.6 0.0 0.0091 14.1 0.0 1.1 1 0 0 1 1 1 1 Enamelin CDC45 PF02724.9 GAP89199.1 - 8.6 4.2 9.1 12 3.8 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein HSA PF07529.8 GAP89200.1 - 6.7e-18 64.2 4.4 6.7e-18 64.2 3.0 5.2 6 0 0 6 6 6 1 HSA Myb_DNA-bind_6 PF13921.1 GAP89200.1 - 1.5e-08 34.5 0.8 1.5e-08 34.5 0.5 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Herpes_LMP1 PF05297.6 GAP89200.1 - 9.2 5.0 9.7 22 3.8 6.7 1.6 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) G-patch_2 PF12656.2 GAP89201.1 - 4.7e-19 68.0 0.7 4.7e-19 68.0 0.5 2.5 2 0 0 2 2 2 1 DExH-box splicing factor binding site CMAS PF02353.15 GAP89202.1 - 2.4e-61 207.2 0.0 3e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 GAP89202.1 - 2.3e-10 40.4 0.0 4.6e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP89202.1 - 4.6e-07 30.2 0.0 8.7e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP89202.1 - 0.00034 20.9 0.0 0.0008 19.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP89202.1 - 0.0089 16.5 0.0 0.03 14.8 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.8 GAP89202.1 - 0.022 14.0 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 MTS PF05175.9 GAP89202.1 - 0.037 13.4 0.0 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 GAP89202.1 - 0.057 12.9 0.0 0.1 12.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 GAP89202.1 - 0.06 13.3 0.0 0.15 12.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 GAP89202.1 - 0.11 12.9 0.1 0.32 11.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain EF-hand_4 PF12763.2 GAP89203.1 - 1.5e-27 95.3 0.0 3.5e-15 55.6 0.0 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.6 GAP89203.1 - 0.00053 19.9 30.4 0.00053 19.9 21.1 7.9 5 3 2 7 7 7 2 Domain of unknown function (DUF1720) EF-hand_7 PF13499.1 GAP89203.1 - 0.0093 16.0 0.4 0.4 10.8 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 GAP89203.1 - 0.017 14.9 0.3 4.7 7.3 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain Dabb PF07876.7 GAP89203.1 - 0.066 13.6 0.0 27 5.3 0.0 3.1 2 0 0 2 2 2 0 Stress responsive A/B Barrel Domain MAP65_ASE1 PF03999.7 GAP89204.1 - 3.1e-68 230.9 27.3 4e-67 227.2 19.2 1.9 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Lectin_N PF03954.9 GAP89204.1 - 0.13 11.6 0.4 0.32 10.3 0.3 1.6 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Baculo_PEP_C PF04513.7 GAP89204.1 - 0.17 11.7 0.0 7.5 6.3 0.0 3.1 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mit_KHE1 PF10173.4 GAP89204.1 - 0.37 10.5 2.3 2.8 7.7 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related Prominin PF05478.6 GAP89204.1 - 1.5 6.2 4.1 12 3.3 0.1 2.6 1 1 2 3 3 3 0 Prominin EF-hand_4 PF12763.2 GAP89205.1 - 8.5e-05 22.2 0.1 0.0003 20.5 0.0 1.8 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand INSIG PF07281.7 GAP89206.1 - 1.2e-43 148.7 1.5 1.6e-43 148.3 1.0 1.2 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) bHLH-MYC_N PF14215.1 GAP89206.1 - 0.019 15.1 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal LON PF02190.11 GAP89207.1 - 8.7e-17 61.4 0.0 1.3e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_4 PF15227.1 GAP89207.1 - 3.7e-06 26.7 6.6 8.8e-06 25.5 4.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 GAP89207.1 - 0.00055 19.8 3.5 0.0012 18.8 2.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAP89207.1 - 0.0055 16.3 3.9 0.013 15.1 2.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAP89207.1 - 0.0074 15.9 4.5 0.19 11.4 2.6 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 GAP89207.1 - 0.014 15.2 4.8 0.036 13.9 3.3 1.8 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.1 GAP89207.1 - 0.069 12.8 1.7 0.15 11.7 1.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAP89207.1 - 0.092 12.4 3.8 0.23 11.2 2.6 1.8 1 0 0 1 1 1 0 zinc-RING finger domain efThoc1 PF11957.3 GAP89208.1 - 9.7e-143 476.2 3.7 1.3e-142 475.8 2.6 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.16 GAP89208.1 - 1e-35 122.8 0.2 2.4e-35 121.6 0.0 1.7 2 0 0 2 2 2 1 Guanylate kinase MMR_HSR1 PF01926.18 GAP89208.1 - 0.0002 21.3 0.0 0.00055 19.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 GAP89208.1 - 0.0082 15.6 0.1 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 GAP89208.1 - 0.012 14.8 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 GAP89208.1 - 0.015 15.1 0.0 0.049 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAP89208.1 - 0.038 14.1 0.0 0.49 10.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 GAP89208.1 - 0.065 14.0 0.2 0.36 11.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 GAP89208.1 - 0.067 13.1 0.0 0.33 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 GAP89208.1 - 0.073 13.3 0.1 0.34 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 GAP89208.1 - 0.1 13.1 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein MobB PF03205.9 GAP89208.1 - 0.14 11.8 0.0 0.41 10.3 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 GAP89208.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_12 PF13087.1 GAP89209.1 - 2.2e-27 95.7 0.0 4.1e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAP89209.1 - 3.8e-25 88.8 0.0 7.1e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAP89209.1 - 1.5e-09 37.4 0.1 2.3e-08 33.6 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 GAP89209.1 - 1.4e-06 28.0 0.0 0.002 17.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 GAP89209.1 - 0.0004 20.2 0.0 0.00085 19.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.1 GAP89209.1 - 0.0019 18.2 0.3 0.072 13.0 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 GAP89209.1 - 0.0019 18.4 0.0 0.01 16.0 0.0 2.4 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAP89209.1 - 0.0027 17.8 0.1 0.015 15.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 GAP89209.1 - 0.0037 16.6 0.0 0.011 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 GAP89209.1 - 0.0045 16.4 0.1 0.044 13.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_17 PF13207.1 GAP89209.1 - 0.011 16.4 0.0 0.54 11.0 0.0 3.4 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.7 GAP89209.1 - 0.016 14.3 0.0 0.056 12.5 0.0 1.9 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.13 GAP89209.1 - 0.044 13.2 0.1 2.3 7.6 0.0 2.7 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 GAP89209.1 - 0.048 13.3 0.7 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase DnaB_C PF03796.10 GAP89209.1 - 0.049 12.5 0.0 0.086 11.7 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain DUF2075 PF09848.4 GAP89209.1 - 0.054 12.4 0.9 0.075 11.9 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.12 GAP89209.1 - 0.063 12.1 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_5 PF07728.9 GAP89209.1 - 0.078 12.6 0.0 0.43 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 GAP89209.1 - 0.088 11.6 0.1 0.2 10.4 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 GAP89209.1 - 0.2 11.8 0.0 0.54 10.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase RecA PF00154.16 GAP89209.1 - 0.27 10.2 0.0 0.43 9.5 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein PIF1 PF05970.9 GAP89209.1 - 0.28 10.0 0.0 20 3.9 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase MIF4G PF02854.14 GAP89210.1 - 1.3e-54 184.7 0.0 2.2e-54 184.0 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 GAP89210.1 - 1.5e-20 72.8 0.3 4.2e-20 71.4 0.2 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Eno-Rase_FAD_bd PF07055.7 GAP89210.1 - 0.086 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain PV-1 PF06637.6 GAP89210.1 - 0.2 10.2 12.9 0.39 9.2 8.9 1.4 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DNA_pol_B PF00136.16 GAP89211.1 - 2.2e-109 366.3 0.9 3.2e-109 365.7 0.6 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 GAP89211.1 - 3.1e-62 209.2 0.0 5.7e-62 208.4 0.0 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 GAP89211.1 - 1.1e-37 129.7 0.0 1.8e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 GAP89211.1 - 6.3e-25 86.7 9.6 1.7e-24 85.3 6.6 1.8 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal PPR_2 PF13041.1 GAP89212.1 - 9.3e-21 73.5 0.3 1e-13 51.0 0.0 3.7 2 1 1 3 3 3 3 PPR repeat family PPR_3 PF13812.1 GAP89212.1 - 8.4e-08 31.9 0.3 0.11 12.8 0.0 5.1 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.15 GAP89212.1 - 8.1e-07 28.6 0.4 0.024 14.5 0.0 5.1 5 1 0 5 5 5 2 PPR repeat PPR_1 PF12854.2 GAP89212.1 - 0.00089 18.6 0.2 8.2 6.0 0.0 4.5 5 0 0 5 5 5 2 PPR repeat DUF1770 PF08589.5 GAP89213.1 - 2.8e-23 82.3 13.5 6.9e-21 74.7 9.4 2.2 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF1770) Nucleoplasmin PF03066.10 GAP89213.1 - 0.0015 18.0 7.7 0.002 17.6 5.3 1.2 1 0 0 1 1 1 1 Nucleoplasmin PBP1_TM PF14812.1 GAP89213.1 - 0.0015 18.8 11.1 0.004 17.4 7.7 1.8 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal SR-25 PF10500.4 GAP89213.1 - 0.021 14.2 1.0 0.026 14.0 0.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RXT2_N PF08595.6 GAP89213.1 - 0.054 13.2 7.3 0.086 12.6 5.1 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Daxx PF03344.10 GAP89213.1 - 0.057 11.9 6.2 0.075 11.5 4.3 1.2 1 0 0 1 1 1 0 Daxx Family FAM177 PF14774.1 GAP89213.1 - 0.093 12.6 1.0 0.15 11.9 0.7 1.3 1 0 0 1 1 1 0 FAM177 family LRS4 PF10422.4 GAP89213.1 - 0.095 12.0 6.9 0.12 11.6 4.8 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Cwf_Cwc_15 PF04889.7 GAP89213.1 - 0.1 12.2 8.5 0.14 11.8 5.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 GAP89213.1 - 0.12 10.2 5.8 0.14 10.0 4.0 1.1 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.6 GAP89213.1 - 0.15 11.0 2.1 0.2 10.6 1.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nucleo_P87 PF07267.6 GAP89213.1 - 0.27 9.8 8.0 0.34 9.5 5.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ORC6 PF05460.8 GAP89213.1 - 0.29 10.1 5.5 0.38 9.7 3.8 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Sigma70_ner PF04546.8 GAP89213.1 - 0.35 10.4 8.0 0.51 9.9 5.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region UPF0560 PF10577.4 GAP89213.1 - 0.55 8.4 6.1 0.68 8.1 4.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 NOA36 PF06524.7 GAP89213.1 - 0.79 8.9 7.6 0.97 8.6 5.3 1.1 1 0 0 1 1 1 0 NOA36 protein Mpp10 PF04006.7 GAP89213.1 - 0.85 7.9 7.5 1.1 7.5 5.2 1.1 1 0 0 1 1 1 0 Mpp10 protein Syntaphilin PF15290.1 GAP89213.1 - 1.7 8.0 4.8 2.4 7.5 3.3 1.1 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp DUF2076 PF09849.4 GAP89213.1 - 1.9 8.4 8.6 2.6 8.0 5.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) CENP-B_dimeris PF09026.5 GAP89213.1 - 2.6 8.3 17.8 4.4 7.5 12.4 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PPP4R2 PF09184.6 GAP89213.1 - 3.3 7.1 11.4 4.1 6.8 7.9 1.1 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.9 GAP89213.1 - 5.8 4.8 6.4 7.1 4.5 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Myc_N PF01056.13 GAP89213.1 - 7.1 5.7 12.6 14 4.7 8.6 1.5 1 1 0 1 1 1 0 Myc amino-terminal region FAM176 PF14851.1 GAP89213.1 - 8.1 6.1 7.5 16 5.1 5.2 1.7 1 1 0 1 1 1 0 FAM176 family WHIM1 PF15612.1 GAP89214.1 - 0.00022 20.9 0.0 0.00097 18.9 0.0 2.1 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 VID27 PF08553.5 GAP89214.1 - 1.2 7.2 8.1 23 3.0 6.0 2.0 2 0 0 2 2 2 0 VID27 cytoplasmic protein CDC45 PF02724.9 GAP89214.1 - 5.1 4.9 6.7 8 4.3 4.6 1.2 1 0 0 1 1 1 0 CDC45-like protein eRF1_2 PF03464.10 GAP89215.1 - 3.2e-46 156.9 0.0 5.6e-46 156.1 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 GAP89215.1 - 6.9e-41 139.0 0.5 1.4e-40 138.1 0.4 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 GAP89215.1 - 3.6e-28 97.7 0.0 6.2e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.21 GAP89215.1 - 0.12 11.8 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PDT PF00800.13 GAP89216.1 - 1.3e-47 161.7 0.0 2.6e-47 160.7 0.0 1.6 1 1 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 GAP89216.1 - 0.00073 18.9 0.0 0.0016 17.8 0.0 1.5 1 0 0 1 1 1 1 ACT domain Trypan_PARP PF05887.6 GAP89216.1 - 0.003 17.3 0.7 0.003 17.3 0.5 1.6 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) E1_dh PF00676.15 GAP89217.1 - 5.6e-114 379.8 0.6 6.9e-114 379.6 0.4 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 GAP89217.1 - 0.0026 16.7 0.2 0.0051 15.7 0.0 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Velvet PF11754.3 GAP89218.1 - 4.5e-56 189.6 0.0 7.9e-56 188.8 0.0 1.3 1 0 0 1 1 1 1 Velvet factor HTH_Tnp_Tc3_2 PF01498.13 GAP89218.1 - 0.061 13.3 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Transposase NAD_binding_4 PF07993.7 GAP89220.1 - 1.4e-34 119.1 0.0 2.1e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 GAP89220.1 - 1.5e-28 99.3 0.0 2.5e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 GAP89220.1 - 2e-10 40.4 0.0 8e-10 38.5 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 GAP89220.1 - 1.2e-05 25.4 0.0 3e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.1 GAP89220.1 - 0.00018 21.5 0.0 0.54 10.2 0.0 2.7 2 0 0 2 2 2 2 NADH(P)-binding adh_short PF00106.20 GAP89220.1 - 0.0011 18.9 0.1 0.0055 16.6 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase UCR_Fe-S_N PF10399.4 GAP89220.1 - 0.049 12.8 0.1 0.99 8.6 0.0 2.5 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Polysacc_synt_2 PF02719.10 GAP89220.1 - 0.055 12.3 0.0 0.089 11.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 GAP89220.1 - 0.11 11.1 0.0 8.6 4.9 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 GAP89220.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Grp1_Fun34_YaaH PF01184.14 GAP89222.1 - 4.9e-52 176.2 14.2 5.8e-52 176.0 9.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Lysis_col PF02402.11 GAP89222.1 - 0.12 11.9 0.2 0.29 10.7 0.1 1.6 1 0 0 1 1 1 0 Lysis protein MAPEG PF01124.13 GAP89224.1 - 2.1e-14 53.2 0.1 2.3e-14 53.0 0.0 1.0 1 0 0 1 1 1 1 MAPEG family Nup_retrotrp_bd PF10599.4 GAP89225.1 - 4.1 8.1 9.6 0.71 10.5 2.8 2.1 2 0 0 2 2 2 0 Retro-transposon transporting motif Polysacc_lyase PF14099.1 GAP89226.1 - 0.02 14.5 5.3 0.031 13.9 3.7 1.3 1 0 0 1 1 1 0 Polysaccharide lyase MFS_2 PF13347.1 GAP89227.1 - 1.2e-07 30.5 6.4 1.2e-07 30.5 4.5 2.4 3 0 0 3 3 3 1 MFS/sugar transport protein PUCC PF03209.10 GAP89227.1 - 8.4e-06 24.7 2.2 1.7e-05 23.7 1.5 1.5 1 0 0 1 1 1 1 PUCC protein PRA1 PF03208.14 GAP89227.1 - 0.76 9.1 5.1 3 7.1 0.3 2.8 2 0 0 2 2 2 0 PRA1 family protein Na_H_Exchanger PF00999.16 GAP89228.1 - 1e-71 241.5 31.2 1.2e-71 241.2 21.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PepSY_TM_2 PF13703.1 GAP89228.1 - 0.027 14.6 0.2 0.027 14.6 0.1 3.2 5 0 0 5 5 5 0 PepSY-associated TM helix Pkinase PF00069.20 GAP89229.1 - 3.5e-38 131.2 0.0 5.5e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP89229.1 - 6.9e-29 100.6 0.0 1e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAP89229.1 - 0.00044 20.0 0.1 0.16 11.6 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 GAP89229.1 - 0.00071 18.6 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 GAP89229.1 - 0.006 15.5 0.0 0.0084 15.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like MFS_1 PF07690.11 GAP89230.1 - 5.8e-39 133.8 23.8 5.8e-39 133.8 16.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Aa_trans PF01490.13 GAP89231.1 - 9.7e-26 90.1 41.4 1.5e-25 89.5 28.7 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein RhoGAP PF00620.22 GAP89232.1 - 1.8e-38 131.5 0.0 3.3e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Med7 PF05983.6 GAP89232.1 - 0.031 14.0 0.2 0.08 12.7 0.0 1.7 2 0 0 2 2 2 0 MED7 protein DUF290 PF01060.18 GAP89232.1 - 0.09 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Transthyretin-like family DUF3543 PF12063.3 GAP89233.1 - 3.9e-91 304.5 0.1 5.6e-91 303.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 GAP89233.1 - 3.4e-61 206.6 0.0 6e-61 205.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP89233.1 - 1.1e-41 142.7 0.0 2.2e-41 141.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 GAP89233.1 - 0.065 12.0 0.0 0.093 11.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Aminotran_3 PF00202.16 GAP89234.1 - 1.5e-107 359.3 0.0 1.8e-107 359.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 GAP89234.1 - 0.00012 21.2 0.0 0.00031 19.9 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 GAP89234.1 - 0.0018 17.3 0.0 0.0025 16.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Glyco_transf_22 PF03901.12 GAP89235.1 - 1.4e-76 258.1 16.7 1.8e-76 257.8 11.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Cullin PF00888.17 GAP89236.1 - 1e-120 404.0 0.0 1.6e-120 403.4 0.0 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 GAP89236.1 - 2.7e-27 94.3 1.7 6.7e-27 93.1 1.2 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain ABC_membrane PF00664.18 GAP89237.1 - 1e-79 267.8 30.2 4.5e-42 144.3 7.7 2.6 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAP89237.1 - 3.8e-51 172.9 0.1 8.3e-29 100.6 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 GAP89237.1 - 6.4e-09 35.3 4.8 0.0048 16.1 0.1 4.2 2 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 GAP89237.1 - 4.9e-07 29.9 0.9 0.042 13.8 0.3 2.6 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 GAP89237.1 - 4.4e-05 22.7 0.3 0.16 11.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 GAP89237.1 - 0.0001 22.2 0.0 0.65 9.9 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.1 GAP89237.1 - 0.00012 22.5 0.2 0.022 15.0 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 GAP89237.1 - 0.00034 20.0 0.0 0.3 10.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAP89237.1 - 0.0021 17.5 1.2 0.99 8.9 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.7 GAP89237.1 - 0.0033 17.0 0.5 0.033 13.8 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Miro PF08477.8 GAP89237.1 - 0.0047 17.4 0.2 4.3 7.8 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein AAA_21 PF13304.1 GAP89237.1 - 0.0087 16.0 0.1 8.6 6.2 0.0 3.8 4 0 0 4 4 3 0 AAA domain AAA_10 PF12846.2 GAP89237.1 - 0.028 13.8 0.0 5 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain Dynamin_N PF00350.18 GAP89237.1 - 0.042 13.6 1.8 1.3 8.8 0.1 2.5 2 0 0 2 2 2 0 Dynamin family RNA_helicase PF00910.17 GAP89237.1 - 0.043 13.9 0.0 3.5 7.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.1 GAP89237.1 - 0.052 13.7 0.9 12 5.9 0.0 3.1 2 1 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 GAP89237.1 - 0.089 12.2 0.1 0.7 9.3 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 GAP89237.1 - 0.093 12.1 0.2 4.6 6.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.9 GAP89237.1 - 0.15 11.7 0.6 22 4.7 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 GAP89237.1 - 0.18 11.3 0.2 1.7 8.1 0.0 2.5 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AIG1 PF04548.11 GAP89237.1 - 0.29 10.2 1.3 6.7 5.7 0.0 2.2 2 0 0 2 2 2 0 AIG1 family DUF87 PF01935.12 GAP89237.1 - 0.32 10.7 5.2 0.34 10.7 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF87 RseC_MucC PF04246.7 GAP89237.1 - 3.5 7.1 7.9 1.2 8.6 0.0 3.6 4 0 0 4 4 4 0 Positive regulator of sigma(E), RseC/MucC DUF2841 PF11001.3 GAP89238.1 - 1.1e-36 125.4 0.1 1.1e-36 125.4 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) p450 PF00067.17 GAP89239.1 - 4.4e-46 157.3 0.0 2.7e-41 141.5 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF1749 PF08538.5 GAP89240.1 - 1.6e-81 273.5 0.0 1.7e-81 273.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 GAP89240.1 - 5.4e-18 65.7 0.3 6.6e-18 65.4 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP89240.1 - 4.9e-10 39.3 0.0 1.1e-09 38.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP89240.1 - 0.00031 20.3 0.4 0.022 14.3 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAP89240.1 - 0.00072 18.8 0.0 0.63 9.2 0.0 2.7 1 1 2 3 3 3 2 Prolyl oligopeptidase family Ser_hydrolase PF06821.8 GAP89240.1 - 0.019 14.5 0.0 0.057 13.0 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase HEAT PF02985.17 GAP89241.1 - 0.023 14.7 6.8 1.3 9.2 0.2 5.4 5 0 0 5 5 5 0 HEAT repeat RRM_1 PF00076.17 GAP89242.1 - 3.9e-14 52.0 0.0 3.6e-07 29.6 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP89242.1 - 1.6e-13 50.3 0.0 2.7e-07 30.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP89242.1 - 5.3e-05 22.9 0.0 0.00018 21.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 GAP89242.1 - 0.075 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 Zip PF02535.17 GAP89242.1 - 2.2 7.1 5.4 2.9 6.8 3.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter WD40 PF00400.27 GAP89243.1 - 0.017 15.0 10.1 5.7 6.9 0.0 6.1 6 0 0 6 6 6 0 WD domain, G-beta repeat MoaC PF01967.16 GAP89244.1 - 8.5e-51 171.1 2.8 1.5e-50 170.4 1.9 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 GAP89244.1 - 3.9e-35 120.3 0.0 1.4e-34 118.4 0.0 1.9 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 GAP89244.1 - 3.4e-19 69.6 0.0 5.6e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 GAP89244.1 - 2.9e-05 24.2 0.0 8e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 GAP89244.1 - 0.00028 20.8 0.0 0.00074 19.5 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain ELO PF01151.13 GAP89246.1 - 5.1e-80 268.3 11.9 6.1e-80 268.1 8.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF2508 PF10704.4 GAP89246.1 - 0.17 12.0 0.0 0.31 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) GMC_oxred_N PF00732.14 GAP89247.1 - 1.5e-45 155.6 0.3 2.7e-45 154.7 0.2 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAP89247.1 - 1.1e-25 90.6 0.0 2.3e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAP89247.1 - 1.9e-06 27.0 1.7 0.0014 17.5 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAP89247.1 - 0.00011 22.2 1.9 0.00047 20.1 1.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAP89247.1 - 0.00017 21.5 0.1 0.00041 20.2 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAP89247.1 - 0.00022 20.1 6.5 0.00091 18.1 4.5 1.8 1 1 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 GAP89247.1 - 0.0013 17.8 0.8 0.002 17.2 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 GAP89247.1 - 0.0066 15.5 0.7 0.015 14.3 0.3 1.7 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 GAP89247.1 - 0.032 12.7 0.9 0.049 12.0 0.6 1.2 1 0 0 1 1 1 0 HI0933-like protein Ins_allergen_rp PF06757.8 GAP89247.1 - 0.14 11.5 0.0 0.8 9.1 0.0 2.0 2 0 0 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification 3HCDH_N PF02737.13 GAP89247.1 - 0.19 11.3 0.1 0.35 10.4 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 GAP89247.1 - 1.6 8.0 3.4 2.6 7.3 2.4 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RELT PF12606.3 GAP89247.1 - 1.7 7.8 5.5 5.6 6.1 3.8 1.9 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 FAD_binding_4 PF01565.18 GAP89250.1 - 2.6e-19 69.0 1.9 7.4e-19 67.6 1.3 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP89250.1 - 7e-09 35.4 0.0 1.5e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like LRR_6 PF13516.1 GAP89252.1 - 8.9e-12 43.7 5.2 0.21 11.7 0.0 7.8 10 0 0 10 10 10 4 Leucine Rich repeat F-box-like PF12937.2 GAP89252.1 - 6.2e-11 41.8 0.1 2.5e-10 39.9 0.1 2.2 2 0 0 2 2 2 1 F-box-like LRR_1 PF00560.28 GAP89252.1 - 2.6e-09 35.8 5.6 1.4 9.2 0.0 7.3 6 2 0 6 6 6 3 Leucine Rich Repeat F-box PF00646.28 GAP89252.1 - 1.1e-07 31.2 0.3 4.9e-07 29.2 0.2 2.2 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.2 GAP89252.1 - 4.3e-05 23.0 5.2 0.92 9.2 0.0 5.8 2 1 4 6 6 6 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAP89252.1 - 8.9e-05 22.1 5.4 2 8.2 0.0 5.0 3 1 2 5 5 5 1 Leucine rich repeat PRANC PF09372.5 GAP89252.1 - 0.17 11.9 0.0 0.51 10.3 0.0 1.8 1 0 0 1 1 1 0 PRANC domain LRR_7 PF13504.1 GAP89252.1 - 0.55 10.6 15.7 17 6.1 0.2 7.1 9 0 0 9 9 9 0 Leucine rich repeat Ste50p-SAM PF09235.5 GAP89252.1 - 1.2 9.2 3.8 12 6.0 0.0 3.4 2 1 1 3 3 3 0 Ste50p, sterile alpha motif HET PF06985.6 GAP89253.1 - 5.7e-24 84.8 0.1 1.3e-23 83.7 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Acetyltransf_4 PF13420.1 GAP89254.1 - 0.0082 16.0 0.1 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAP89254.1 - 0.013 15.6 0.0 0.044 13.9 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain CVNH PF08881.5 GAP89255.1 - 2.8e-14 53.2 0.9 3.4e-14 52.9 0.7 1.1 1 0 0 1 1 1 1 CVNH domain ABA_GPCR PF12430.3 GAP89256.1 - 7.7e-55 185.0 0.2 1.4e-54 184.2 0.1 1.4 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 GAP89256.1 - 8.4e-20 70.5 0.0 8.6e-19 67.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) MRP-L46 PF11788.3 GAP89257.1 - 8.4e-28 97.2 1.1 1.4e-27 96.5 0.1 1.9 3 0 0 3 3 3 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 GAP89257.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 NUDIX domain Pinin_SDK_memA PF04696.8 GAP89258.1 - 2e-19 69.4 19.0 2e-19 69.4 13.2 2.7 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region Pex26 PF07163.7 GAP89258.1 - 0.0045 15.9 1.6 0.01 14.7 1.1 1.5 1 0 0 1 1 1 1 Pex26 protein LMBR1 PF04791.11 GAP89258.1 - 0.068 11.7 0.2 0.14 10.7 0.2 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1752 PF08550.5 GAP89258.1 - 7.2 6.2 6.5 1.4 8.5 0.0 3.1 3 0 0 3 3 3 0 Fungal protein of unknown function (DUF1752) Abhydrolase_6 PF12697.2 GAP89259.1 - 6.7e-29 101.3 0.2 9.9e-29 100.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP89259.1 - 1.2e-14 54.4 0.0 1.1e-12 48.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP89259.1 - 4.7e-11 42.6 0.0 2.2e-10 40.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAP89259.1 - 0.00025 20.8 0.0 0.00056 19.7 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase EHN PF06441.7 GAP89259.1 - 0.022 14.6 0.0 0.059 13.2 0.0 1.7 1 0 0 1 1 1 0 Epoxide hydrolase N terminus DLH PF01738.13 GAP89259.1 - 0.12 11.6 0.0 0.37 10.0 0.0 1.9 2 1 0 2 2 2 0 Dienelactone hydrolase family E1-E2_ATPase PF00122.15 GAP89260.1 - 2.3e-21 75.9 0.0 4.1e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 GAP89260.1 - 8e-18 65.2 0.1 2.2e-17 63.8 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAP89260.1 - 2.7e-14 54.0 0.6 2e-13 51.2 0.4 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAP89260.1 - 5.6e-12 45.4 0.0 1.6e-11 43.9 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAP89260.1 - 0.00082 19.0 0.5 0.0031 17.1 0.3 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 GAP89260.1 - 0.034 14.3 1.2 0.055 13.6 0.1 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Pyr_redox_2 PF07992.9 GAP89261.1 - 4.4e-27 95.2 0.0 6.5e-26 91.4 0.0 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAP89261.1 - 2.1e-13 50.4 0.0 2.6e-11 43.7 0.1 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP89261.1 - 0.0008 19.5 0.2 0.37 10.8 0.1 3.5 3 2 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase XhlA PF10779.4 GAP89261.1 - 1.1 9.1 5.3 22 5.0 0.8 2.7 2 0 0 2 2 2 0 Haemolysin XhlA Acetyltransf_1 PF00583.19 GAP89262.1 - 2e-07 30.9 0.0 2.7e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAP89262.1 - 5.6e-07 29.6 0.0 8.8e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAP89262.1 - 1.8e-05 24.8 0.0 3.7e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAP89262.1 - 8e-05 22.4 0.2 0.00017 21.4 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAP89262.1 - 0.00039 20.2 0.0 0.00054 19.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 GAP89262.1 - 0.0047 16.6 0.0 0.0072 16.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 GAP89262.1 - 0.01 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.1 GAP89264.1 - 2.5e-79 266.7 22.9 3.4e-79 266.3 15.9 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAP89264.1 - 6.6e-13 47.8 21.6 8.7e-13 47.4 15.0 1.1 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.13 GAP89264.1 - 0.016 13.7 4.8 0.096 11.1 0.0 2.5 2 0 0 2 2 2 0 Transmembrane amino acid transporter protein Phage_B PF02304.10 GAP89265.1 - 0.11 12.8 1.6 0.32 11.2 1.1 1.8 1 0 0 1 1 1 0 Scaffold protein B p47_phox_C PF08944.6 GAP89265.1 - 3.8 7.7 11.8 1.2 9.3 0.2 3.5 2 1 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain Oxysterol_BP PF01237.13 GAP89265.1 - 7.7 4.8 6.5 61 1.9 4.7 1.9 2 0 0 2 2 2 0 Oxysterol-binding protein BRCT PF00533.21 GAP89266.1 - 0.011 15.8 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 GAP89266.1 - 0.016 15.0 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain OLF PF02191.11 GAP89266.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Olfactomedin-like domain Use1 PF09753.4 GAP89268.1 - 3.9e-11 42.8 0.0 4.6e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 Membrane fusion protein Use1 DUF3347 PF11827.3 GAP89268.1 - 0.022 14.7 8.1 0.29 11.1 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) DUF605 PF04652.11 GAP89268.1 - 0.031 13.6 14.6 0.042 13.2 10.2 1.2 1 0 0 1 1 1 0 Vta1 like DUF4648 PF15505.1 GAP89268.1 - 1.6 8.9 7.5 1.6 8.9 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4648) PsaN PF05479.6 GAP89268.1 - 2.5 8.1 6.3 4.5 7.2 4.4 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) DCP2 PF05026.8 GAP89269.1 - 4e-36 122.7 0.7 7e-36 122.0 0.5 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 GAP89269.1 - 6.2e-16 58.2 0.0 1.2e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain SIN1 PF05422.7 GAP89271.1 - 2.1e-39 135.4 0.2 7.7e-18 64.3 0.0 3.5 3 1 0 3 3 3 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 GAP89271.1 - 0.00098 19.0 0.0 0.0027 17.5 0.0 1.8 1 0 0 1 1 1 1 GLUT4 regulating protein TUG RBD PF02196.10 GAP89271.1 - 0.075 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Raf-like Ras-binding domain SNF PF00209.13 GAP89272.1 - 2.1e-74 250.9 35.0 2.1e-74 250.9 24.2 2.3 2 1 0 2 2 2 1 Sodium:neurotransmitter symporter family Cation_ATPase_C PF00689.16 GAP89272.1 - 0.00034 20.2 2.4 0.00034 20.2 1.7 3.4 3 2 2 5 5 5 1 Cation transporting ATPase, C-terminus DUF3810 PF12725.2 GAP89272.1 - 0.26 10.1 1.0 0.48 9.2 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) PRCC PF10253.4 GAP89273.1 - 1.1e-31 110.8 0.0 1.1e-31 110.8 0.0 2.6 3 0 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting DUF2796 PF10986.3 GAP89274.1 - 0.0039 17.1 1.1 0.0059 16.6 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2796) UCH PF00443.24 GAP89275.1 - 1.3e-45 155.5 0.5 1.3e-45 155.5 0.4 2.5 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.3 GAP89275.1 - 3.6e-18 65.2 0.0 7.6e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH_1 PF13423.1 GAP89275.1 - 4.1e-18 65.8 0.2 8e-18 64.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_P_pop3 PF08228.6 GAP89276.1 - 1.3e-08 34.8 0.0 4.3e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 RNase P subunit Pop3 NOC3p PF07540.6 GAP89277.1 - 8.9e-26 90.0 0.1 4.6e-25 87.7 0.0 2.3 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.12 GAP89277.1 - 7.9e-24 83.9 0.0 4.1e-23 81.6 0.0 2.2 3 0 0 3 3 3 1 CBF/Mak21 family UPF0113 PF03657.8 GAP89278.1 - 1.4e-07 31.3 0.0 3.2e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0113) AA_kinase PF00696.23 GAP89279.1 - 2.2e-40 138.7 1.5 3.3e-40 138.1 1.1 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 GAP89279.1 - 2.2e-13 49.7 0.0 1.6e-12 46.9 0.0 2.5 2 1 0 2 2 2 1 PUA domain Peptidase_M76 PF09768.4 GAP89280.1 - 3.5e-65 218.6 3.1 4.3e-65 218.3 2.1 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 GAP89280.1 - 0.013 15.1 2.6 0.013 15.1 1.8 1.7 1 1 0 1 1 1 0 SprT-like family Pkinase PF00069.20 GAP89281.1 - 6.2e-70 235.3 0.0 7.7e-70 234.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP89281.1 - 2.2e-43 148.1 0.0 3e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP89281.1 - 1.8e-07 30.3 0.0 1.2e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 GAP89281.1 - 0.0023 17.0 0.0 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 GAP89281.1 - 0.0029 16.9 0.1 0.0071 15.7 0.0 1.7 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL APH PF01636.18 GAP89281.1 - 0.012 15.3 0.0 0.032 13.9 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 GAP89281.1 - 0.014 14.7 0.0 0.13 11.5 0.0 2.2 2 1 1 3 3 3 0 RIO1 family DUF4267 PF14087.1 GAP89282.1 - 1e-14 54.0 4.2 1.2e-14 53.8 2.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) ADH_zinc_N PF00107.21 GAP89283.1 - 1.1e-24 86.4 1.3 7.8e-24 83.6 0.4 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP89283.1 - 1.1e-18 67.0 1.6 2.3e-18 65.9 1.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 GAP89283.1 - 6.6e-05 22.8 0.1 0.00012 22.0 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.14 GAP89283.1 - 0.00033 19.8 0.0 0.00066 18.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 GAP89283.1 - 0.00036 20.9 0.1 0.0011 19.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP89283.1 - 0.0012 19.2 0.0 0.0028 18.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain AlaDh_PNT_C PF01262.16 GAP89283.1 - 0.0023 17.5 0.4 0.0045 16.5 0.3 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 GAP89283.1 - 0.004 16.8 0.6 0.0061 16.2 0.4 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 GAP89283.1 - 0.0055 17.2 0.2 0.013 16.0 0.0 1.9 2 1 0 2 2 1 1 Methyltransferase domain CMAS PF02353.15 GAP89283.1 - 0.0075 15.3 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NAD_binding_2 PF03446.10 GAP89283.1 - 0.011 15.6 0.2 0.016 15.0 0.2 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ELFV_dehydrog PF00208.16 GAP89283.1 - 0.073 12.6 0.2 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Methyltransf_31 PF13847.1 GAP89283.1 - 0.083 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MacB_PCD PF12704.2 GAP89283.1 - 0.087 12.4 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 MacB-like periplasmic core domain ThiF PF00899.16 GAP89283.1 - 0.091 12.5 0.5 0.21 11.3 0.4 1.6 1 0 0 1 1 1 0 ThiF family ApbA PF02558.11 GAP89283.1 - 0.095 12.1 0.1 0.18 11.2 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.1 GAP89283.1 - 0.1 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain Catalase PF00199.14 GAP89284.1 - 2.1e-160 533.6 0.4 2.9e-160 533.1 0.3 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 GAP89284.1 - 6.2e-19 67.6 0.0 1.2e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 GAP89284.1 - 1.4e-12 47.2 0.0 3.6e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family LBP_BPI_CETP_C PF02886.12 GAP89284.1 - 0.072 12.3 0.1 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 LBP / BPI / CETP family, C-terminal domain HD PF01966.17 GAP89285.1 - 2.8e-09 37.0 0.0 4.4e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 HD domain DUF4112 PF13430.1 GAP89286.1 - 8.9e-30 102.7 0.2 1.2e-29 102.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Ribonuc_red_sm PF00268.16 GAP89287.1 - 8.5e-120 398.9 2.2 1e-119 398.7 1.5 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF1220 PF06758.8 GAP89287.1 - 0.093 12.5 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Repeat of unknown function (DUF1220) SRP9-21 PF05486.7 GAP89288.1 - 4.6e-29 99.9 1.4 6.4e-29 99.5 1.0 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) APC_CDC26 PF10471.4 GAP89288.1 - 1.7 9.4 7.7 0.48 11.1 2.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 NST1 PF13945.1 GAP89288.1 - 3.3 7.7 7.3 0.26 11.3 1.4 1.7 2 0 0 2 2 2 0 Salt tolerance down-regulator SNF2_N PF00176.18 GAP89289.1 - 8.8e-70 234.8 0.0 1.5e-69 234.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAP89289.1 - 1.3e-14 53.7 0.0 3.5e-14 52.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 GAP89289.1 - 0.03 14.0 0.0 0.12 12.1 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain Ribosomal_S11 PF00411.14 GAP89290.1 - 9.7e-41 138.3 0.3 1.2e-40 138.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 GAP89290.1 - 0.048 12.5 0.0 0.058 12.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Ribosomal_L30_N PF08079.7 GAP89291.1 - 1.1e-25 89.4 15.3 1.8e-25 88.7 10.6 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 GAP89291.1 - 1.7e-19 69.1 2.8 1.9e-19 68.9 0.8 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e ERCC4 PF02732.10 GAP89291.1 - 0.11 12.1 0.2 0.26 11.0 0.1 1.7 2 0 0 2 2 2 0 ERCC4 domain Fe-S_biosyn PF01521.15 GAP89292.1 - 8.8e-11 41.7 0.0 8e-05 22.5 0.0 2.1 1 1 0 2 2 2 2 Iron-sulphur cluster biosynthesis YcfA PF07927.7 GAP89293.1 - 0.067 13.1 0.2 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 YcfA-like protein Pentapeptide_4 PF13599.1 GAP89293.1 - 0.18 11.6 0.0 0.66 9.8 0.0 1.9 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) Mpv17_PMP22 PF04117.7 GAP89294.1 - 2e-10 40.1 2.1 4.2e-09 35.8 1.4 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family Gly-zipper_OmpA PF13436.1 GAP89294.1 - 0.24 11.0 4.2 0.62 9.7 2.6 1.8 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Chitin_bind_3 PF03067.10 GAP89295.1 - 6.8e-10 39.4 0.1 1.2e-09 38.7 0.0 1.4 1 1 0 1 1 1 1 Chitin binding domain ApbA_C PF08546.6 GAP89296.1 - 1.7e-26 92.6 0.0 2.7e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 GAP89296.1 - 6e-22 77.7 0.0 1e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Myb_DNA-bind_6 PF13921.1 GAP89297.1 - 3.7e-15 55.7 0.1 3.7e-07 30.1 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 GAP89297.1 - 5e-11 42.4 0.1 0.00038 20.4 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Acyl-CoA_dh_1 PF00441.19 GAP89298.1 - 5.5e-30 104.4 4.6 3.2e-29 101.9 3.2 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAP89298.1 - 4.8e-19 68.9 0.2 2.2e-18 66.8 0.2 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 GAP89298.1 - 9.8e-14 50.6 0.1 2.3e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 GAP89298.1 - 2.8e-12 47.0 5.1 2.8e-12 47.0 3.5 2.8 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain SR-25 PF10500.4 GAP89298.1 - 0.73 9.2 6.9 1.3 8.4 4.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CoA_transf_3 PF02515.12 GAP89299.1 - 3.2e-62 209.1 0.1 6.3e-62 208.2 0.1 1.5 1 0 0 1 1 1 1 CoA-transferase family III SNF2_N PF00176.18 GAP89300.1 - 8.3e-84 280.8 1.1 8.3e-84 280.8 0.8 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 GAP89300.1 - 2.1e-20 72.4 0.1 6.4e-20 70.8 0.1 1.8 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 GAP89300.1 - 1.8e-19 69.3 0.2 7.5e-17 60.9 0.0 3.6 4 0 0 4 4 4 1 Helicase conserved C-terminal domain SnAC PF14619.1 GAP89300.1 - 7.2e-17 61.3 2.6 7.2e-17 61.3 1.8 3.8 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 GAP89300.1 - 6.1e-15 54.7 12.3 6.1e-15 54.7 8.5 3.8 5 0 0 5 5 5 1 HSA QLQ PF08880.6 GAP89300.1 - 9.5e-09 34.5 3.2 9.5e-09 34.5 2.3 2.5 2 0 0 2 2 2 1 QLQ WD40 PF00400.27 GAP89301.1 - 4.8e-24 83.3 14.4 7e-06 25.7 0.8 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat MraZ PF02381.13 GAP89301.1 - 0.11 12.2 0.0 25 4.6 0.0 2.5 2 0 0 2 2 2 0 MraZ protein SURF2 PF05477.6 GAP89301.1 - 0.62 9.1 5.4 0.81 8.7 2.9 1.7 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) Mg_trans_NIPA PF05653.9 GAP89302.1 - 1.2e-60 205.0 3.7 9.4e-57 192.2 1.7 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 GAP89302.1 - 0.0015 18.6 0.4 0.0015 18.6 0.3 3.5 3 1 1 4 4 4 1 Multidrug resistance efflux transporter EamA PF00892.15 GAP89302.1 - 0.014 15.4 3.3 0.014 15.4 2.3 4.1 3 1 1 4 4 4 0 EamA-like transporter family LRR19-TM PF15176.1 GAP89302.1 - 0.14 11.8 0.1 0.36 10.5 0.1 1.8 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF4401 PF14351.1 GAP89302.1 - 0.23 10.4 12.5 0.14 11.1 7.0 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4401) DUF1772 PF08592.6 GAP89302.1 - 0.71 9.5 6.6 2 8.1 0.8 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) Prothymosin PF03247.9 GAP89302.1 - 2.1 8.5 9.7 0.044 13.9 2.1 1.6 2 0 0 2 2 2 0 Prothymosin/parathymosin family HLH PF00010.21 GAP89303.1 - 2.9e-14 52.4 0.0 6.3e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.16 GAP89303.1 - 0.034 14.1 0.1 0.034 14.1 0.1 2.3 3 0 0 3 3 3 0 bZIP transcription factor MerR-DNA-bind PF09278.6 GAP89303.1 - 0.051 13.9 2.0 0.11 12.9 1.4 1.4 1 0 0 1 1 1 0 MerR, DNA binding IncA PF04156.9 GAP89303.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 IncA protein DUF3166 PF11365.3 GAP89303.1 - 0.28 11.6 3.8 0.3 11.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) Sec10 PF07393.6 GAP89303.1 - 0.42 8.7 1.4 0.53 8.4 1.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 ORC6 PF05460.8 GAP89303.1 - 1.5 7.8 7.9 2.4 7.1 5.5 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PBD PF00786.23 GAP89306.1 - 0.0092 16.3 1.1 0.18 12.2 0.0 3.1 2 0 0 2 2 2 1 P21-Rho-binding domain S1 PF00575.18 GAP89307.1 - 3.8e-87 286.4 40.8 1.1e-13 51.0 0.4 13.2 13 0 0 13 13 13 11 S1 RNA binding domain TPR_14 PF13428.1 GAP89307.1 - 7e-09 35.5 2.2 0.076 13.6 0.0 5.1 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAP89307.1 - 4.3e-07 30.4 1.4 0.00026 21.5 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAP89307.1 - 9.6e-07 29.0 3.3 0.066 13.5 0.0 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat Suf PF05843.9 GAP89307.1 - 0.00041 20.1 0.1 0.00041 20.1 0.1 4.3 2 2 1 3 3 2 2 Suppressor of forked protein (Suf) TPR_17 PF13431.1 GAP89307.1 - 0.00052 20.0 0.2 6.7 7.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAP89307.1 - 0.0057 16.2 1.0 0.41 10.3 0.1 2.6 2 0 0 2 2 2 1 TPR repeat TPR_6 PF13174.1 GAP89307.1 - 0.0064 16.8 1.9 14 6.4 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat PAS_11 PF14598.1 GAP89307.1 - 0.0094 15.8 0.5 0.14 12.0 0.0 3.0 3 1 0 3 3 3 1 PAS domain TPR_12 PF13424.1 GAP89307.1 - 0.033 14.1 0.4 0.36 10.7 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAP89307.1 - 0.47 10.4 1.6 15 5.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Fmp27 PF10344.4 GAP89309.1 - 6.9e-224 745.3 0.0 1.2e-223 744.5 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 GAP89309.1 - 1.9e-164 547.8 2.2 1.9e-164 547.8 1.5 2.5 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 GAP89309.1 - 3.5e-147 490.6 4.1 3.5e-147 490.6 2.8 2.2 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 GAP89309.1 - 8.6e-54 181.6 0.0 1.8e-53 180.6 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 GAP89309.1 - 5.6e-50 169.1 1.3 1.1e-49 168.1 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 GAP89309.1 - 2.1e-35 121.2 0.0 9.2e-35 119.1 0.0 2.3 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain EAP30 PF04157.11 GAP89310.1 - 2.6e-41 141.2 0.0 3.7e-20 72.0 0.0 2.0 2 0 0 2 2 2 2 EAP30/Vps36 family Ribosomal_S9 PF00380.14 GAP89311.1 - 3.3e-38 130.6 0.2 3.8e-38 130.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 AAR2 PF05282.6 GAP89312.1 - 2.5e-45 154.9 0.0 3.7e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 AAR2 protein Glyco_hydro_61 PF03443.9 GAP89314.1 - 1.1e-52 178.9 0.4 1.3e-52 178.7 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DEAD PF00270.24 GAP89315.1 - 6.8e-46 155.8 0.0 6.4e-44 149.4 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP89315.1 - 4.6e-29 100.0 0.0 8.4e-29 99.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAP89315.1 - 8.4e-05 22.4 0.0 0.00021 21.1 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 GAP89315.1 - 0.00063 18.2 0.2 0.068 11.5 0.0 2.9 3 1 0 3 3 3 2 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 GAP89315.1 - 0.0032 17.4 0.0 0.0054 16.6 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain POTRA_2 PF08479.6 GAP89315.1 - 0.056 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 POTRA domain, ShlB-type Phos_pyr_kin PF08543.7 GAP89316.1 - 2.4e-88 295.4 0.2 3.4e-88 295.0 0.1 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 GAP89316.1 - 1e-48 165.8 0.1 1.5e-48 165.3 0.1 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 GAP89316.1 - 6.3e-10 38.6 0.2 1.1e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.12 GAP89316.1 - 0.063 12.5 2.0 0.33 10.1 1.4 2.2 1 1 0 1 1 1 0 Carbohydrate kinase HK PF02110.10 GAP89316.1 - 0.084 12.0 2.8 1.3 8.1 1.9 2.4 1 1 0 1 1 1 0 Hydroxyethylthiazole kinase family RICTOR_N PF14664.1 GAP89317.1 - 6.4e-137 456.0 0.1 5.9e-136 452.9 0.1 2.1 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 GAP89317.1 - 6.8e-90 300.0 0.0 3.8e-88 294.3 0.0 3.1 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 GAP89317.1 - 2.2e-42 143.6 0.1 1.7e-39 134.3 0.0 3.4 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 GAP89317.1 - 1.3e-28 98.7 1.1 3e-27 94.3 0.0 3.7 6 0 0 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 GAP89317.1 - 2.7e-13 49.4 7.1 4.6e-13 48.7 4.1 2.1 2 0 0 2 2 2 1 Hr1 repeat Uds1 PF15456.1 GAP89317.1 - 0.16 11.9 11.2 0.048 13.6 5.3 1.9 2 0 0 2 2 2 0 Up-regulated During Septation DUF2443 PF10398.4 GAP89317.1 - 0.43 10.4 3.4 0.27 11.0 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) IncA PF04156.9 GAP89317.1 - 0.46 10.0 5.2 0.94 9.0 3.6 1.4 1 0 0 1 1 1 0 IncA protein TPR_11 PF13414.1 GAP89318.1 - 5.7e-22 77.1 6.2 1.2e-11 44.0 0.1 3.2 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 GAP89318.1 - 2.6e-16 58.4 3.5 1.6e-08 33.8 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAP89318.1 - 2.8e-15 54.9 4.7 1.9e-06 27.3 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAP89318.1 - 3.4e-11 42.0 1.2 4.5e-05 22.9 0.0 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAP89318.1 - 1.3e-09 37.8 1.1 3.2e-06 26.9 0.0 2.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAP89318.1 - 8.4e-09 34.5 0.4 1.2e-06 27.8 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAP89318.1 - 5.1e-08 32.8 0.1 0.12 12.9 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAP89318.1 - 1.8e-07 30.8 0.1 0.0027 17.7 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat PB1 PF00564.19 GAP89318.1 - 1.1e-06 28.2 0.5 1.9e-06 27.4 0.3 1.4 1 0 0 1 1 1 1 PB1 domain TPR_9 PF13371.1 GAP89318.1 - 5e-05 23.0 0.1 0.28 11.0 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAP89318.1 - 8.7e-05 23.0 0.5 0.0014 19.2 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAP89318.1 - 0.0021 18.5 0.1 0.053 14.1 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 GAP89318.1 - 0.023 15.1 0.2 37 5.1 0.0 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 GAP89318.1 - 0.053 13.6 1.1 0.2 11.8 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 GRP PF07172.6 GAP89318.1 - 0.077 13.4 10.5 0.17 12.3 7.3 1.6 1 0 0 1 1 1 0 Glycine rich protein family TPR_10 PF13374.1 GAP89318.1 - 0.14 12.1 0.0 6 6.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat HMA PF00403.21 GAP89319.1 - 1.6e-13 50.5 0.1 2.9e-13 49.7 0.1 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.15 GAP89319.1 - 2.3e-10 40.8 0.0 3.7e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Ribosomal_L13 PF00572.13 GAP89320.1 - 6.8e-38 129.6 0.0 9.2e-38 129.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Uricase PF01014.13 GAP89321.1 - 2.5e-83 277.0 0.0 4.4e-45 153.1 0.2 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.14 GAP89321.1 - 0.092 12.3 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Plasmid recombination enzyme Polysacc_deac_1 PF01522.16 GAP89322.1 - 4e-29 100.7 0.1 6.6e-29 100.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 GAP89322.1 - 6e-05 22.9 18.0 6e-05 22.9 12.5 5.8 5 1 1 6 6 6 3 Chitin recognition protein DEDD_Tnp_IS110 PF01548.12 GAP89325.1 - 0.041 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Transposase RNase_PH_C PF03725.10 GAP89325.1 - 0.063 13.2 0.0 0.4 10.6 0.0 2.2 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 Sen15 PF09631.5 GAP89325.1 - 0.096 12.9 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Sen15 protein Dioxygenase_C PF00775.16 GAP89326.1 - 5.5e-41 139.8 0.0 8.6e-41 139.1 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 GAP89326.1 - 1e-13 51.0 0.0 2.2e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 GAP89326.1 - 0.027 14.5 0.0 0.068 13.2 0.0 1.7 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain DUF4266 PF14086.1 GAP89326.1 - 0.23 11.9 3.5 13 6.3 2.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4266) DUF3336 PF11815.3 GAP89327.1 - 3.9e-49 165.8 2.5 6.8e-49 165.1 1.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 GAP89327.1 - 8.2e-20 71.6 0.0 2.8e-19 69.8 0.0 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase DUF1669 PF07894.7 GAP89327.1 - 0.2 10.8 2.3 0.11 11.7 0.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1669) Arf PF00025.16 GAP89328.1 - 9.4e-66 220.3 0.0 1e-65 220.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 GAP89328.1 - 2.4e-12 46.2 0.1 1.3e-08 34.0 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 GAP89328.1 - 2.1e-08 33.5 0.0 2.7e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 GAP89328.1 - 1.4e-07 32.0 0.0 1.9e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 GAP89328.1 - 1.5e-07 31.3 0.0 1.9e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 GAP89328.1 - 7.1e-07 28.7 0.0 9.3e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 GAP89328.1 - 6.2e-06 25.5 0.0 6.6e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAP89328.1 - 0.0016 17.8 0.1 0.069 12.5 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 GAP89328.1 - 0.082 12.3 0.0 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CENP-M PF11111.3 GAP89328.1 - 0.088 12.0 0.0 0.21 10.7 0.0 1.5 2 0 0 2 2 2 0 Centromere protein M (CENP-M) cobW PF02492.14 GAP89328.1 - 0.095 12.1 0.0 7.2 6.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2457 PF10446.4 GAP89329.1 - 6.4e-136 453.7 25.2 6.4e-136 453.7 17.4 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) RNA_pol_3_Rpc31 PF11705.3 GAP89329.1 - 2.3 8.0 27.2 0.048 13.5 13.5 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Ycf1 PF05758.7 GAP89329.1 - 4.3 4.9 7.7 8.4 3.9 5.4 1.4 1 0 0 1 1 1 0 Ycf1 Usp PF00582.21 GAP89329.1 - 6.3 6.9 9.0 11 6.1 0.1 2.9 2 0 0 2 2 2 0 Universal stress protein family ATP-synt_DE_N PF02823.11 GAP89330.1 - 3.3e-20 71.6 0.0 4.9e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain PalH PF08733.5 GAP89333.1 - 5.6e-100 334.5 0.1 6.7e-100 334.3 0.0 1.0 1 0 0 1 1 1 1 PalH/RIM21 TRAM_LAG1_CLN8 PF03798.11 GAP89334.1 - 3.3e-33 114.9 23.0 3.3e-33 114.9 16.0 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 GAP89334.1 - 7.9e-24 82.9 0.0 2.1e-23 81.5 0.0 1.8 1 0 0 1 1 1 1 TRAM1-like protein ABC_tran PF00005.22 GAP89335.1 - 2e-32 112.3 0.0 4.9e-32 111.0 0.0 1.7 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 GAP89335.1 - 3.3e-27 95.6 7.5 3.3e-27 95.6 5.2 1.8 3 0 0 3 3 2 1 ABC transporter transmembrane region SMC_N PF02463.14 GAP89335.1 - 3.1e-06 26.5 1.5 7e-05 22.1 0.4 2.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAP89335.1 - 3.1e-05 24.0 0.1 0.0085 16.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 GAP89335.1 - 0.00029 20.0 0.0 0.001 18.2 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 GAP89335.1 - 0.0011 18.9 0.0 0.0025 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain SbcCD_C PF13558.1 GAP89335.1 - 0.0014 18.4 0.1 0.057 13.3 0.1 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 GAP89335.1 - 0.0026 17.2 0.0 0.0071 15.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Potyvirid-P3 PF13608.1 GAP89335.1 - 0.012 14.7 0.3 0.021 13.9 0.2 1.3 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein SPC25 PF06703.6 GAP89335.1 - 0.047 13.2 2.7 7.4 6.1 1.1 2.6 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF2786 PF10979.3 GAP89335.1 - 0.2 11.3 5.8 0.44 10.3 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) VWA_3 PF13768.1 GAP89336.1 - 0.043 13.5 0.5 0.091 12.4 0.1 1.8 2 1 0 2 2 2 0 von Willebrand factor type A domain DUF1387 PF07139.6 GAP89336.1 - 0.22 11.0 1.1 0.31 10.6 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1387) WxL PF13731.1 GAP89336.1 - 0.4 10.4 8.4 0.69 9.6 5.8 1.3 1 0 0 1 1 1 0 WxL domain surface cell wall-binding AAA PF00004.24 GAP89337.1 - 1.9e-98 325.7 0.0 9.6e-48 161.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 GAP89337.1 - 7.4e-20 70.6 1.1 2.2e-19 69.2 0.4 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 GAP89337.1 - 1.2e-13 51.3 0.0 2.6e-07 30.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 GAP89337.1 - 1.3e-13 50.5 0.0 6.7e-06 25.3 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 GAP89337.1 - 4.4e-13 49.1 0.4 9.4e-07 28.6 0.1 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 GAP89337.1 - 1.5e-12 47.6 0.0 1.3e-05 25.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAP89337.1 - 4e-12 46.4 0.4 0.00069 19.7 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAP89337.1 - 1.1e-11 45.0 0.0 0.0004 20.4 0.0 3.6 2 2 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 GAP89337.1 - 3.1e-11 44.1 0.0 0.00021 22.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 GAP89337.1 - 3.1e-09 36.0 0.0 0.00093 18.0 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 GAP89337.1 - 2.3e-08 34.0 0.0 0.0012 18.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 GAP89337.1 - 3.3e-08 33.1 1.6 0.0083 15.8 0.0 3.1 3 0 0 3 3 2 2 Part of AAA domain IstB_IS21 PF01695.12 GAP89337.1 - 3.3e-08 33.1 0.0 0.0053 16.2 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 GAP89337.1 - 4.5e-08 32.7 7.0 0.022 14.1 0.0 4.6 3 2 2 5 5 4 3 AAA domain Zeta_toxin PF06414.7 GAP89337.1 - 1.3e-07 30.9 0.0 0.0078 15.3 0.0 2.7 3 0 0 3 3 2 2 Zeta toxin Mg_chelatase PF01078.16 GAP89337.1 - 1.6e-07 30.6 0.2 0.0057 15.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 GAP89337.1 - 4.7e-07 29.9 0.0 0.026 14.6 0.0 2.9 3 0 0 3 3 2 2 RNA helicase KaiC PF06745.8 GAP89337.1 - 9.1e-07 28.2 0.7 0.23 10.5 0.0 3.5 2 1 1 3 3 3 2 KaiC CDC48_2 PF02933.12 GAP89337.1 - 1e-06 28.2 0.0 2.4e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_24 PF13479.1 GAP89337.1 - 1.5e-06 27.9 0.2 0.095 12.2 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.1 GAP89337.1 - 1.7e-06 28.3 0.0 0.086 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 GAP89337.1 - 2.9e-06 27.2 0.0 0.0022 17.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 GAP89337.1 - 3.4e-06 27.0 0.0 0.089 12.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 GAP89337.1 - 4.7e-06 25.7 0.0 0.023 13.6 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 GAP89337.1 - 7.1e-06 25.0 0.1 0.043 12.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Vps4_C PF09336.5 GAP89337.1 - 7.7e-06 25.7 0.1 3.8e-05 23.4 0.0 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain Sigma54_activ_2 PF14532.1 GAP89337.1 - 1.1e-05 25.4 0.0 0.05 13.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 GAP89337.1 - 1.2e-05 25.1 0.0 4 7.0 0.0 4.0 2 2 1 3 3 3 0 Archaeal ATPase NACHT PF05729.7 GAP89337.1 - 1.5e-05 24.6 0.1 0.085 12.5 0.0 3.2 3 0 0 3 3 3 1 NACHT domain Sigma54_activat PF00158.21 GAP89337.1 - 1.7e-05 24.3 0.0 0.17 11.3 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 GAP89337.1 - 2.5e-05 24.5 0.0 0.23 11.7 0.0 3.4 2 1 0 2 2 2 2 ABC transporter Bac_DnaA PF00308.13 GAP89337.1 - 5.2e-05 22.9 0.0 0.39 10.3 0.0 3.1 3 0 0 3 3 3 2 Bacterial dnaA protein PhoH PF02562.11 GAP89337.1 - 0.00013 21.2 0.2 0.5 9.5 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.6 GAP89337.1 - 0.00018 21.1 0.0 0.59 9.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 GAP89337.1 - 0.00019 21.0 0.0 0.49 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 GAP89337.1 - 0.00054 19.6 0.0 0.83 9.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 GAP89337.1 - 0.00068 18.5 0.0 0.55 9.0 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain NTPase_1 PF03266.10 GAP89337.1 - 0.001 18.7 0.3 0.64 9.6 0.0 3.7 4 0 0 4 4 3 1 NTPase DUF2075 PF09848.4 GAP89337.1 - 0.0016 17.5 0.0 1.5 7.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 GAP89337.1 - 0.0067 15.9 0.0 0.28 10.6 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 GAP89337.1 - 0.0076 15.2 0.4 1.4 7.8 0.0 3.5 2 2 1 4 4 4 1 KAP family P-loop domain IPT PF01745.11 GAP89337.1 - 0.01 14.9 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase UPF0079 PF02367.12 GAP89337.1 - 0.016 14.8 0.1 8.9 5.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 GAP89337.1 - 0.029 13.8 0.6 1.6 8.1 0.0 3.4 3 1 0 4 4 4 0 AAA-like domain T2SE PF00437.15 GAP89337.1 - 0.042 12.7 0.0 1.8 7.3 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Zot PF05707.7 GAP89337.1 - 0.054 12.9 0.2 16 4.8 0.1 3.8 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) AAA_23 PF13476.1 GAP89337.1 - 0.064 13.5 0.0 4.3 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain SKI PF01202.17 GAP89337.1 - 0.081 12.7 0.1 8.3 6.2 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase AFG1_ATPase PF03969.11 GAP89337.1 - 0.092 11.5 0.0 11 4.7 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase UFD1 PF03152.9 GAP89337.1 - 0.12 11.4 0.0 8.7 5.4 0.0 2.3 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 MobB PF03205.9 GAP89337.1 - 0.13 11.9 0.9 3.5 7.3 0.0 3.2 4 0 0 4 4 2 0 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.5 GAP89337.1 - 0.14 11.3 0.5 11 5.1 0.0 2.8 3 0 0 3 3 2 0 Chromatin associated protein KTI12 AMP-binding PF00501.23 GAP89338.1 - 4.5e-84 282.2 0.5 7.2e-84 281.5 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme Ferric_reduct PF01794.14 GAP89338.1 - 6.6 6.8 15.0 0.11 12.6 3.5 2.3 1 1 1 2 2 2 0 Ferric reductase like transmembrane component ECH PF00378.15 GAP89339.1 - 6.3e-61 205.6 3.6 8.7e-61 205.1 2.5 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 GAP89339.1 - 0.031 14.0 0.0 0.094 12.4 0.0 1.8 1 1 0 1 1 1 0 Peptidase family S49 Se-cys_synth_N PF12390.3 GAP89339.1 - 0.42 10.7 4.0 0.23 11.5 0.4 2.4 2 0 0 2 2 2 0 Selenocysteine synthase N terminal Aa_trans PF01490.13 GAP89340.1 - 1.1e-58 198.7 32.1 1.3e-58 198.4 22.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CBM-like PF14683.1 GAP89341.1 - 9.6e-08 31.8 0.0 2.4e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 GAP89341.1 - 3.3e-07 30.3 0.0 9.1e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II Zip PF02535.17 GAP89342.1 - 4 6.3 6.8 4.2 6.2 4.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TPR_11 PF13414.1 GAP89343.1 - 0.0051 16.4 1.3 3.6 7.2 0.0 3.4 2 1 1 4 4 4 2 TPR repeat TPR_12 PF13424.1 GAP89343.1 - 0.011 15.6 3.9 0.5 10.3 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAP89343.1 - 0.022 14.9 0.4 4.8 7.6 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAP89343.1 - 0.83 10.4 5.5 0.35 11.5 0.5 2.9 3 2 0 3 3 3 0 Tetratricopeptide repeat FMN_bind_2 PF04299.7 GAP89345.1 - 7.2e-51 172.0 0.0 8.7e-51 171.7 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Flg_hook PF02120.11 GAP89345.1 - 0.12 12.0 0.4 7.5 6.2 0.0 2.8 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK Invasin_D3 PF09134.5 GAP89346.1 - 0.053 13.3 0.1 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Invasin, domain 3 Protoglobin PF11563.3 GAP89347.1 - 9.4e-53 178.0 0.1 1.3e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Protoglobin Lipase_GDSL_2 PF13472.1 GAP89348.1 - 0.013 15.6 0.1 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DUF1445 PF07286.7 GAP89349.1 - 9e-21 74.0 0.1 1.1e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) Fungal_trans PF04082.13 GAP89351.1 - 5.8e-32 110.5 0.1 1.2e-31 109.5 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP89351.1 - 2.3e-08 33.7 14.9 3.8e-08 33.1 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.24 GAP89352.1 - 2.9e-08 33.2 7.2 4.8e-08 32.5 5.0 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 GAP89352.1 - 0.24 10.7 3.8 0.41 9.9 2.6 1.3 1 0 0 1 1 1 0 PHD-finger Iso_dh PF00180.15 GAP89353.1 - 4.4e-126 420.5 0.0 5.2e-126 420.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF745 PF05335.8 GAP89353.1 - 0.64 9.5 2.1 1 8.8 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) TauD PF02668.11 GAP89354.1 - 7.9e-49 166.6 0.2 9.4e-49 166.3 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Acetyltransf_1 PF00583.19 GAP89355.1 - 8.2e-11 41.7 0.0 1.8e-10 40.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAP89355.1 - 1.3e-10 41.3 0.0 2.8e-10 40.1 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAP89355.1 - 3e-05 24.0 0.0 0.00055 20.0 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAP89355.1 - 7.3e-05 22.6 0.0 0.00058 19.7 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAP89355.1 - 0.014 15.2 0.0 0.04 13.8 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.5 GAP89355.1 - 0.028 14.1 0.0 0.087 12.5 0.0 1.8 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_4 PF13420.1 GAP89355.1 - 0.066 13.1 0.0 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF4451 PF14616.1 GAP89356.1 - 4.9e-35 120.0 0.3 8.2e-35 119.2 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) TFIIA PF03153.8 GAP89357.1 - 0.33 10.8 6.3 0.47 10.2 4.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CorA PF01544.13 GAP89358.1 - 1.3e-13 50.6 0.0 2e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein NB-ARC PF00931.17 GAP89361.1 - 6.7e-13 48.1 0.0 1.3e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.1 GAP89361.1 - 4.7e-10 39.2 15.1 0.0029 17.4 0.0 5.6 2 1 5 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.12 GAP89361.1 - 1.9e-08 33.5 11.7 0.0045 16.8 0.2 6.6 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAP89361.1 - 7.6e-08 31.8 6.2 0.01 15.4 0.0 5.3 4 1 1 5 5 5 3 TPR repeat Abhydrolase_6 PF12697.2 GAP89361.1 - 9.5e-07 28.9 0.0 5.6e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family TPR_1 PF00515.23 GAP89361.1 - 1.7e-06 27.3 13.1 0.12 12.0 0.0 6.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.1 GAP89361.1 - 0.00054 19.7 0.6 10 6.1 0.0 5.9 5 1 0 5 5 5 1 Tetratricopeptide repeat AAA_22 PF13401.1 GAP89361.1 - 0.00058 20.0 0.0 0.0018 18.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain TPR_14 PF13428.1 GAP89361.1 - 0.00092 19.6 5.6 0.091 13.4 0.1 5.5 5 1 2 7 7 7 1 Tetratricopeptide repeat PGAP1 PF07819.8 GAP89361.1 - 0.0025 17.4 0.0 0.0051 16.4 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 GAP89361.1 - 0.0041 16.4 0.0 0.008 15.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) TPR_7 PF13176.1 GAP89361.1 - 0.018 14.8 2.4 26 4.9 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF900 PF05990.7 GAP89361.1 - 0.062 12.6 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Actin PF00022.14 GAP89362.1 - 8.6e-30 103.4 0.0 2.2e-18 65.8 0.0 3.0 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 GAP89362.1 - 0.0032 16.1 0.0 0.014 13.9 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein DUF2451 PF10474.4 GAP89362.1 - 0.045 13.4 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) SNF2_N PF00176.18 GAP89363.1 - 2.5e-45 154.5 0.0 4.5e-45 153.7 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAP89363.1 - 4.2e-16 58.5 0.4 1e-15 57.3 0.3 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SAM_1 PF00536.25 GAP89363.1 - 0.0038 17.3 0.1 0.048 13.8 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) HDA2-3 PF11496.3 GAP89363.1 - 0.064 12.0 3.8 0.47 9.2 0.0 2.8 3 0 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 DUF2854 PF11016.3 GAP89363.1 - 0.14 11.6 1.2 0.38 10.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2854) GSH_synth_ATP PF03917.12 GAP89364.1 - 6e-104 347.5 0.0 7.4e-104 347.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 GAP89364.1 - 4.2e-28 97.5 0.0 6.7e-28 96.8 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SET PF00856.23 GAP89366.1 - 9.1e-08 32.5 0.1 0.00019 21.7 0.1 2.8 2 1 1 3 3 3 2 SET domain TPR_11 PF13414.1 GAP89366.1 - 0.0059 16.2 0.5 2.5 7.8 0.2 2.6 2 0 0 2 2 2 2 TPR repeat mono-CXXC PF15626.1 GAP89366.1 - 0.63 10.0 4.8 3.6 7.6 2.3 2.6 2 0 0 2 2 2 0 single CXXC unit CsbD PF05532.7 GAP89367.1 - 0.00026 20.5 8.0 0.0092 15.6 1.5 2.3 2 1 0 2 2 2 2 CsbD-like BCNT PF07572.7 GAP89368.1 - 2.6e-27 94.5 2.6 5.7e-27 93.4 1.8 1.6 1 0 0 1 1 1 1 Bucentaur or craniofacial development Pro_isomerase PF00160.16 GAP89369.1 - 2.6e-47 160.8 0.2 5e-47 159.9 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.10 GAP89369.1 - 5.6e-06 26.2 0.0 2.1e-05 24.3 0.0 2.0 1 0 0 1 1 1 1 U-box domain Lung_7-TM_R PF06814.8 GAP89370.1 - 5e-73 245.6 11.8 6e-73 245.3 8.2 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor PrgI PF12666.2 GAP89370.1 - 0.77 9.9 23.7 0.098 12.8 2.5 3.6 1 1 1 3 3 3 0 PrgI family protein Methyltransf_28 PF02636.12 GAP89371.1 - 3.4e-79 265.8 0.0 4.3e-79 265.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pkinase PF00069.20 GAP89372.1 - 2.8e-61 206.9 0.0 4.4e-61 206.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP89372.1 - 7.8e-30 103.7 0.0 1.4e-29 102.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP89372.1 - 0.0004 19.4 0.0 0.00075 18.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAP89372.1 - 0.0075 15.3 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAP89372.1 - 0.12 12.0 4.8 0.74 9.5 3.3 2.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Rtf2 PF04641.7 GAP89372.1 - 8.9 5.4 13.7 14 4.7 9.5 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger MCLC PF05934.6 GAP89373.1 - 3.4 5.8 5.6 4.9 5.3 3.9 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Glyco_hydro_61 PF03443.9 GAP89374.1 - 3.7e-14 53.0 0.0 4.7e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_cc PF11790.3 GAP89376.1 - 4e-35 121.3 0.1 5.8e-35 120.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core CAP PF00188.21 GAP89376.1 - 1.7e-20 73.7 1.1 1.7e-20 73.7 0.8 2.0 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Cytotoxic PF09000.5 GAP89376.1 - 0.011 15.6 0.1 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 Cytotoxic Octopine_DH PF02317.12 GAP89379.1 - 6e-42 142.8 0.0 1e-41 142.1 0.0 1.4 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain NmrA PF05368.8 GAP89379.1 - 3.6e-16 59.1 0.0 1.1e-14 54.2 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 GAP89379.1 - 3.7e-14 53.1 0.2 5.5e-11 42.7 0.0 2.5 2 1 0 2 2 2 2 NADH(P)-binding NAD_Gly3P_dh_N PF01210.18 GAP89379.1 - 3.6e-13 49.5 0.3 2.2e-12 47.0 0.0 2.2 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 GAP89379.1 - 2.1e-09 37.6 0.2 5.3e-06 26.7 0.0 2.7 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 GAP89379.1 - 4e-09 36.0 0.1 2.3e-07 30.3 0.0 2.4 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA CPSase_L_chain PF00289.17 GAP89379.1 - 0.0035 17.4 1.2 0.7 10.0 0.0 3.1 3 1 0 3 3 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain CoA_binding PF02629.14 GAP89379.1 - 0.0048 17.3 2.0 0.21 12.0 0.1 3.1 2 1 0 2 2 2 1 CoA binding domain NAD_binding_2 PF03446.10 GAP89379.1 - 0.0052 16.6 0.0 0.2 11.4 0.0 2.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.9 GAP89379.1 - 0.0062 15.9 0.0 0.014 14.7 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.17 GAP89379.1 - 0.01 14.7 0.0 0.019 13.8 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A ThiF PF00899.16 GAP89379.1 - 0.01 15.6 1.5 0.97 9.2 0.1 2.8 2 1 0 2 2 2 0 ThiF family IlvN PF07991.7 GAP89379.1 - 0.011 15.0 0.7 0.11 11.9 0.1 2.6 2 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_8 PF13450.1 GAP89379.1 - 0.057 13.4 0.1 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Semialdhyde_dh PF01118.19 GAP89379.1 - 0.078 13.2 0.3 2 8.7 0.0 2.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 GAP89379.1 - 0.093 12.7 0.5 3.6 7.5 0.0 2.8 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAP89379.1 - 0.13 12.1 0.0 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 GAP89379.1 - 0.13 12.3 0.2 20 5.3 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 GAP89379.1 - 0.16 11.0 1.2 1.1 8.2 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain Rossmann-like PF10727.4 GAP89379.1 - 0.17 11.6 0.8 20 4.8 0.1 3.1 3 1 0 3 3 2 0 Rossmann-like domain 3HCDH_N PF02737.13 GAP89379.1 - 1.1 8.8 2.7 1.5 8.4 0.0 2.5 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Exo_endo_phos PF03372.18 GAP89380.1 - 5e-09 36.4 1.0 6.1e-09 36.1 0.7 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3445 PF11927.3 GAP89381.1 - 3.9e-53 180.4 0.0 4.8e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF3445 PF11927.3 GAP89382.1 - 7.2e-10 38.6 0.1 1e-09 38.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF829 PF05705.9 GAP89383.1 - 2.8e-35 122.1 0.0 4.1e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) MFS_1 PF07690.11 GAP89384.1 - 2e-27 95.8 49.8 5.1e-25 87.9 34.5 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP89384.1 - 2.6e-09 36.1 11.1 2.6e-09 36.1 7.7 2.7 2 1 2 4 4 4 1 Sugar (and other) transporter TRI12 PF06609.8 GAP89384.1 - 5.1e-05 21.6 20.0 9.5e-05 20.7 11.9 2.0 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.7 GAP89384.1 - 3.4 7.6 11.4 0.21 11.5 0.2 3.8 5 0 0 5 5 5 0 Poxvirus virion envelope protein A14 p450 PF00067.17 GAP89385.1 - 2e-32 112.3 0.0 1.1e-18 67.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Oxidored_molyb PF00174.14 GAP89386.1 - 1.9e-44 151.0 0.0 4e-44 150.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 GAP89386.1 - 1.7e-20 72.9 1.7 2e-20 72.7 0.1 1.8 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Isochorismatase PF00857.15 GAP89387.1 - 8.7e-16 58.3 0.0 1e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DrsE_2 PF13686.1 GAP89387.1 - 0.075 12.8 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family Glyco_hydro_43 PF04616.9 GAP89390.1 - 1.6e-98 329.2 0.0 2.5e-98 328.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Peptidase_A4 PF01828.12 GAP89391.1 - 3.2e-78 261.5 6.9 3.9e-78 261.2 4.8 1.1 1 0 0 1 1 1 1 Peptidase A4 family NRDE PF05742.7 GAP89392.1 - 1.7e-40 139.0 0.0 8.9e-37 126.8 0.0 2.0 2 0 0 2 2 2 2 NRDE protein Tfb2 PF03849.9 GAP89394.1 - 7.4e-128 426.2 0.0 1.1e-127 425.7 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 GAP89394.1 - 4.9e-05 23.0 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Na_H_antiport_1 PF06965.7 GAP89394.1 - 0.054 12.2 0.0 0.085 11.6 0.0 1.2 1 0 0 1 1 1 0 Na+/H+ antiporter 1 SinI PF08671.5 GAP89394.1 - 0.076 12.4 0.0 0.41 10.1 0.0 2.3 2 0 0 2 2 2 0 Anti-repressor SinI Cu_amine_oxid PF01179.15 GAP89395.1 - 1.8e-170 567.1 0.0 2.2e-170 566.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 GAP89395.1 - 3.3e-21 75.2 0.1 6.2e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 GAP89395.1 - 5.2e-15 55.2 0.0 8.6e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain RdgC PF04381.7 GAP89395.1 - 0.019 13.9 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative exonuclease, RdgC DUF1996 PF09362.5 GAP89396.1 - 7.7e-83 277.7 4.2 7.7e-83 277.7 2.9 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF1996) Glyco_hydro_18 PF00704.23 GAP89399.1 - 1.3e-61 208.9 0.1 1.8e-61 208.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 GAP89399.1 - 5.9e-10 38.9 101.4 7.4e-05 22.6 17.3 5.8 5 0 0 5 5 5 4 Chitin recognition protein Pyr_redox_3 PF13738.1 GAP89400.1 - 4.4e-25 88.9 0.0 9.7e-24 84.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAP89400.1 - 1.7e-15 56.2 0.0 1.9e-14 52.7 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 GAP89400.1 - 2.7e-10 39.6 0.6 2.9e-08 33.0 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 GAP89400.1 - 4e-09 36.3 0.0 1.1e-07 31.7 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAP89400.1 - 1.5e-06 28.2 0.4 0.058 13.2 0.0 3.6 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAP89400.1 - 3.5e-06 26.3 1.7 0.0004 19.5 0.0 2.7 3 0 0 3 3 3 1 Thi4 family Pyr_redox PF00070.22 GAP89400.1 - 1.4e-05 25.3 0.1 0.013 15.9 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAP89400.1 - 1.7e-05 23.9 7.6 0.00014 20.9 0.0 3.3 2 2 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAP89400.1 - 0.0012 18.6 4.4 0.52 10.0 0.1 4.1 4 0 0 4 4 4 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 GAP89400.1 - 0.0013 18.8 0.0 0.46 10.5 0.0 2.9 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 GAP89400.1 - 0.002 17.0 0.0 0.88 8.3 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 GAP89400.1 - 0.0024 16.8 0.4 0.065 12.1 0.0 3.0 3 1 0 3 3 3 1 Lycopene cyclase protein Trp_halogenase PF04820.9 GAP89400.1 - 0.0035 16.0 0.1 0.5 8.9 0.0 2.4 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_7 PF13241.1 GAP89400.1 - 0.016 15.4 0.0 0.14 12.3 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding ApbA PF02558.11 GAP89400.1 - 0.017 14.5 0.6 0.2 11.1 0.0 2.6 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 GAP89400.1 - 0.14 11.3 0.0 1.5 7.9 0.0 2.4 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NTP_transferase PF00483.18 GAP89401.1 - 8.1e-27 94.0 0.0 1.3e-26 93.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 GAP89401.1 - 4.6e-08 32.2 3.2 2.3e-06 26.8 0.0 3.4 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.7 GAP89401.1 - 0.027 13.0 0.0 0.46 8.9 0.0 2.1 2 0 0 2 2 2 0 L-fucokinase Proteasome PF00227.21 GAP89402.1 - 5.5e-60 201.9 0.1 6.7e-60 201.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 GAP89402.1 - 3.3e-15 55.0 0.2 6.9e-14 50.8 0.1 2.4 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 GAP89402.1 - 0.17 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit SPOC PF07744.8 GAP89403.1 - 1.1e-13 51.7 0.0 2.6e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.9 GAP89403.1 - 7.6e-13 48.5 0.9 1.5e-12 47.6 0.7 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 GAP89403.1 - 7.5e-09 35.1 8.1 1.4e-08 34.2 5.6 1.5 1 0 0 1 1 1 1 PHD-finger ECIST_Cterm PF14784.1 GAP89403.1 - 1.1 9.1 3.4 0.65 9.9 0.3 2.1 2 1 1 3 3 3 0 C-terminal domain of the ECSIT protein Nup54 PF13874.1 GAP89404.1 - 0.0047 16.5 8.8 0.0047 16.5 6.1 6.0 2 2 2 5 5 5 1 Nucleoporin complex subunit 54 WD40_alt PF14077.1 GAP89404.1 - 0.0048 16.4 0.8 0.17 11.5 0.0 3.6 3 0 0 3 3 3 1 Alternative WD40 repeat motif Myosin_tail_1 PF01576.14 GAP89404.1 - 0.014 13.1 107.2 0.0014 16.4 63.9 3.4 1 1 2 3 3 3 0 Myosin tail Reo_sigmaC PF04582.7 GAP89404.1 - 0.12 11.5 39.5 0.018 14.2 5.6 5.3 2 2 2 5 5 5 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 GAP89404.1 - 2.1 8.2 98.7 2 8.2 6.9 8.2 1 1 5 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 GAP89404.1 - 5.1 6.4 88.1 1.5 8.1 21.9 5.7 1 1 4 5 5 5 0 Intermediate filament protein HAD_2 PF13419.1 GAP89405.1 - 2.1e-32 112.7 1.5 2.8e-32 112.3 1.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAP89405.1 - 1.2e-07 31.3 0.0 1.9e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 GAP89405.1 - 1.7e-05 25.3 0.0 0.0002 21.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase CobN-Mg_chel PF02514.11 GAP89405.1 - 0.034 11.5 0.0 0.044 11.1 0.0 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase p450 PF00067.17 GAP89406.1 - 5.2e-71 239.5 0.0 6.5e-71 239.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MatE PF01554.13 GAP89407.1 - 7.9e-52 175.1 32.2 2.5e-32 111.7 8.8 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 GAP89407.1 - 0.00013 21.7 6.8 0.00013 21.7 4.7 4.4 1 1 4 6 6 6 2 Polysaccharide biosynthesis C-terminal domain Como_SCP PF02248.11 GAP89407.1 - 0.011 15.0 0.5 0.022 14.1 0.4 1.4 1 0 0 1 1 1 0 Small coat protein HSP70 PF00012.15 GAP89408.1 - 4.2e-09 34.8 0.2 8.3e-06 24.0 0.0 2.9 3 0 0 3 3 3 3 Hsp70 protein FlgN PF05130.7 GAP89408.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 FlgN protein UPF0242 PF06785.6 GAP89409.1 - 0.059 12.0 0.2 0.085 11.5 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) S1-P1_nuclease PF02265.11 GAP89410.1 - 6.8e-54 183.1 0.0 7.7e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Pyr_redox_3 PF13738.1 GAP89411.1 - 1.1e-23 84.4 0.0 6.1e-22 78.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAP89411.1 - 4e-18 64.9 0.1 4.1e-15 54.9 0.2 3.1 3 1 0 3 3 3 2 Flavin-binding monooxygenase-like DAO PF01266.19 GAP89411.1 - 2.7e-12 46.2 0.0 8.8e-08 31.4 0.0 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 GAP89411.1 - 3e-12 46.1 0.2 8.3e-09 34.8 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 GAP89411.1 - 9e-11 41.6 0.1 2.3e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAP89411.1 - 1e-07 32.0 0.0 5.1e-05 23.2 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAP89411.1 - 9.1e-06 25.5 1.1 0.0022 17.8 0.0 3.5 4 1 0 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 GAP89411.1 - 0.0003 19.8 0.0 0.02 13.8 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 GAP89411.1 - 0.0021 17.1 0.1 0.0053 15.8 0.0 1.6 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 GAP89411.1 - 0.036 12.5 0.1 0.41 9.0 0.0 2.4 2 0 0 2 2 2 0 HI0933-like protein Amino_oxidase PF01593.19 GAP89411.1 - 0.039 13.0 0.0 0.42 9.6 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 GAP89411.1 - 0.047 14.0 0.0 1.8 9.0 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAP89411.1 - 0.052 12.4 0.0 5.2 5.8 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 GAP89411.1 - 0.075 13.1 0.0 2.7 8.0 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 GAP89411.1 - 0.18 10.8 0.0 0.31 10.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Asp PF00026.18 GAP89412.1 - 3.9e-69 233.3 6.0 4.6e-69 233.0 4.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAP89412.1 - 2.8e-05 24.1 0.0 0.00016 21.7 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 GAP89412.1 - 6.7e-05 23.3 2.8 0.016 15.7 0.6 3.2 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 GAP89412.1 - 0.0056 16.2 0.1 0.014 14.9 0.1 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Glyco_hydro_18 PF00704.23 GAP89413.1 - 2e-97 326.7 11.3 2.3e-97 326.5 7.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PmbA_TldD PF01523.11 GAP89415.1 - 3.2 6.9 5.6 3.6 6.7 3.9 1.0 1 0 0 1 1 1 0 Putative modulator of DNA gyrase NAD_binding_8 PF13450.1 GAP89416.1 - 1e-11 44.6 0.2 3.4e-11 42.9 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAP89416.1 - 2.6e-10 39.7 0.0 1.3e-08 34.1 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAP89416.1 - 4.1e-05 23.9 0.0 0.29 11.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP89416.1 - 6.5e-05 23.0 0.0 0.00052 20.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAP89416.1 - 9e-05 21.1 0.0 0.019 13.4 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 GAP89416.1 - 0.00021 20.2 0.1 0.00036 19.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 GAP89416.1 - 0.00025 20.8 0.1 0.0035 17.1 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 GAP89416.1 - 0.00042 20.2 0.0 0.009 15.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 GAP89416.1 - 0.00042 19.5 0.0 0.03 13.4 0.0 2.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 GAP89416.1 - 0.0008 18.4 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 GAP89416.1 - 0.0043 16.1 0.0 0.0072 15.4 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 GAP89416.1 - 0.019 14.0 0.0 0.083 11.9 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.15 GAP89416.1 - 0.057 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 GAP89416.1 - 0.12 11.7 0.0 0.56 9.6 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Ldh_1_N PF00056.18 GAP89416.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Cyclin_N PF00134.18 GAP89417.1 - 3.4e-12 46.0 0.0 5.5e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 GAP89417.1 - 4.1e-11 43.5 0.2 1e-10 42.2 0.1 1.8 1 1 0 1 1 1 1 Cyclin Pkinase PF00069.20 GAP89418.1 - 1.3e-71 240.8 0.0 1.6e-71 240.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP89418.1 - 1.3e-31 109.6 0.0 1.6e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP89418.1 - 0.0037 16.2 0.0 0.0072 15.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAP89418.1 - 0.0062 16.3 0.1 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 GAP89418.1 - 0.017 13.9 0.1 0.032 13.0 0.1 1.4 1 1 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 GAP89418.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL 2OG-FeII_Oxy_2 PF13532.1 GAP89419.1 - 2.6e-33 115.5 0.0 3.1e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 GAP89419.1 - 0.0091 16.4 0.0 0.065 13.7 0.0 2.3 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily Peptidase_M20 PF01546.23 GAP89420.1 - 7.5e-26 90.8 0.3 1.3e-25 90.0 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Abhydrolase_6 PF12697.2 GAP89420.1 - 1.4e-23 83.9 0.4 1.4e-23 83.9 0.3 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP89420.1 - 3.1e-08 33.5 0.0 6.3e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family M20_dimer PF07687.9 GAP89420.1 - 2.5e-07 30.4 0.0 5.3e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 GAP89420.1 - 0.028 14.1 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 DUF221 PF02714.10 GAP89421.1 - 2.6e-76 256.5 19.8 9.5e-48 162.7 5.7 2.6 2 1 1 3 3 3 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 GAP89421.1 - 1.1e-40 138.7 1.1 1.1e-40 138.7 0.8 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 GAP89421.1 - 1.5e-21 76.0 0.9 3.1e-21 75.0 0.6 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 GAP89421.1 - 1.4e-06 28.6 0.0 3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Syndecan PF01034.15 GAP89421.1 - 0.0044 16.6 1.0 0.0044 16.6 0.7 3.0 4 0 0 4 4 4 1 Syndecan domain SPOR PF05036.8 GAP89421.1 - 0.097 12.8 0.3 0.27 11.4 0.0 1.9 2 0 0 2 2 2 0 Sporulation related domain CD99L2 PF12301.3 GAP89421.1 - 0.33 10.6 1.8 0.75 9.4 1.3 1.5 1 0 0 1 1 1 0 CD99 antigen like protein 2 TPR_MLP1_2 PF07926.7 GAP89422.1 - 1.3e-29 102.6 21.8 1.3e-29 102.6 15.1 18.0 7 3 8 16 16 16 6 TPR/MLP1/MLP2-like protein BNR PF02012.15 GAP89423.1 - 7e-08 31.1 35.1 0.39 10.7 0.3 10.3 10 0 0 10 10 10 6 BNR/Asp-box repeat BNR_2 PF13088.1 GAP89423.1 - 0.046 13.0 18.6 0.35 10.1 1.2 5.3 2 2 2 4 4 4 0 BNR repeat-like domain TauD PF02668.11 GAP89424.1 - 1.4e-37 129.8 0.0 2.3e-37 129.0 0.0 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sporozoite_P67 PF05642.6 GAP89425.1 - 0.22 9.3 5.5 0.2 9.5 3.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2076 PF09849.4 GAP89425.1 - 0.38 10.7 7.9 0.53 10.3 5.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) RAP1 PF07218.6 GAP89425.1 - 1.4 6.9 2.8 1.6 6.7 1.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1180 PF06679.7 GAP89426.1 - 0.00031 20.6 5.2 0.00032 20.6 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) DUF2782 PF11191.3 GAP89426.1 - 0.22 11.5 2.0 0.27 11.2 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) MGC-24 PF05283.6 GAP89426.1 - 8.2 6.1 8.7 8.8 6.0 6.0 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Glyco_transf_15 PF01793.11 GAP89427.1 - 3e-111 371.5 8.3 4e-111 371.1 5.7 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Hira PF07569.6 GAP89428.1 - 8.8e-87 289.9 0.0 1.9e-86 288.8 0.0 1.6 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 GAP89428.1 - 1.7e-42 141.7 18.9 5.2e-07 29.2 0.1 8.5 8 0 0 8 8 8 7 WD domain, G-beta repeat HIRA_B PF09453.5 GAP89428.1 - 2e-12 46.2 1.2 5.4e-12 44.9 0.8 1.8 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 GAP89428.1 - 0.00029 20.4 0.5 36 4.1 0.0 5.1 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat IKI3 PF04762.7 GAP89428.1 - 0.14 9.8 0.3 0.78 7.4 0.0 2.2 3 0 0 3 3 3 0 IKI3 family DUF2400 PF09674.5 GAP89429.1 - 0.0031 17.2 0.1 0.0034 17.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2400) Translin PF01997.11 GAP89429.1 - 0.0081 15.7 0.1 0.01 15.4 0.1 1.0 1 0 0 1 1 1 1 Translin family CASP_C PF08172.7 GAP89429.1 - 0.068 12.1 0.0 0.083 11.8 0.0 1.1 1 0 0 1 1 1 0 CASP C terminal RPEL PF02755.10 GAP89431.1 - 6.5e-09 34.8 0.1 1.8e-06 27.0 0.1 2.4 2 0 0 2 2 2 2 RPEL repeat F-box PF00646.28 GAP89431.1 - 1.6e-07 30.7 0.1 3.5e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAP89431.1 - 1.7e-06 27.6 0.1 5.2e-06 26.0 0.1 1.9 1 0 0 1 1 1 1 F-box-like DUF1974 PF09317.6 GAP89432.1 - 0.31 10.4 4.8 0.55 9.5 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) Med7 PF05983.6 GAP89433.1 - 8.4e-56 188.2 0.1 9.9e-56 187.9 0.0 1.0 1 0 0 1 1 1 1 MED7 protein 23S_rRNA_IVP PF05635.6 GAP89434.1 - 0.044 13.6 0.0 0.12 12.3 0.0 1.7 1 1 0 1 1 1 0 23S rRNA-intervening sequence protein DivIVA PF05103.8 GAP89436.1 - 0.00038 20.4 0.1 0.00044 20.3 0.1 1.1 1 0 0 1 1 1 1 DivIVA protein E2R135 PF11570.3 GAP89436.1 - 0.011 15.7 0.1 0.013 15.5 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 Fmp27_WPPW PF10359.4 GAP89436.1 - 0.025 13.0 0.3 0.029 12.7 0.2 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain zf-ZPR1 PF03367.8 GAP89436.1 - 0.073 12.2 0.0 0.091 11.9 0.0 1.1 1 0 0 1 1 1 0 ZPR1 zinc-finger domain Pro-kuma_activ PF09286.6 GAP89437.1 - 9.1e-41 139.2 0.0 1.4e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 GAP89437.1 - 7e-10 38.5 0.0 1.5e-09 37.4 0.0 1.5 1 1 0 1 1 1 1 Subtilase family zf-C2H2_4 PF13894.1 GAP89438.1 - 6.4e-09 35.5 10.2 0.00053 20.1 0.1 3.5 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 GAP89438.1 - 8.1e-06 25.8 11.8 0.0036 17.5 0.1 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 GAP89438.1 - 0.023 14.8 0.2 0.098 12.8 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAP89438.1 - 0.24 11.6 4.5 2 8.7 0.0 3.4 3 1 0 3 3 3 0 Zinc-finger of C2H2 type Homeobox_KN PF05920.6 GAP89439.1 - 0.011 15.4 1.2 0.015 14.9 0.2 1.7 2 0 0 2 2 2 0 Homeobox KN domain Zn_clus PF00172.13 GAP89439.1 - 0.019 14.8 7.5 0.036 13.9 5.2 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-SNAP50_C PF12251.3 GAP89439.1 - 0.068 12.5 3.4 0.1 12.0 2.4 1.2 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal PALP PF00291.20 GAP89440.1 - 4e-55 187.2 0.1 7.4e-55 186.3 0.1 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.23 GAP89440.1 - 6e-29 100.9 0.6 2e-28 99.2 0.1 1.9 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAP89440.1 - 3.4e-15 55.7 0.0 1e-14 54.1 0.0 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF2457 PF10446.4 GAP89441.1 - 0.29 9.8 4.5 1 8.0 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2457) NAD_binding_1 PF00175.16 GAP89442.1 - 1.8e-27 96.0 0.0 2.7e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 GAP89442.1 - 1.2e-15 57.4 0.0 2.2e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 GAP89442.1 - 1e-06 28.7 0.0 0.0077 16.1 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Amidoligase_2 PF12224.3 GAP89443.1 - 7.2e-12 45.4 0.1 9.7e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Putative amidoligase enzyme Med15 PF09606.5 GAP89443.1 - 0.1 10.8 0.0 0.14 10.3 0.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Nuc_deoxyrib_tr PF05014.10 GAP89444.1 - 9.3e-05 22.2 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase CAF-1_p150 PF11600.3 GAP89445.1 - 0.3 10.4 19.6 0.35 10.2 12.7 1.8 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TFIIA PF03153.8 GAP89445.1 - 6.8 6.4 19.3 0.83 9.4 8.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit LUC7 PF03194.10 GAP89446.1 - 3.5e-66 223.3 0.1 4.3e-66 223.0 0.1 1.0 1 0 0 1 1 1 1 LUC7 N_terminus PLU-1 PF08429.6 GAP89446.1 - 0.004 16.0 0.0 0.0051 15.7 0.0 1.2 1 0 0 1 1 1 1 PLU-1-like protein Gpi16 PF04113.9 GAP89448.1 - 1.1e-225 750.0 0.0 1.3e-225 749.7 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component SRR1 PF07985.7 GAP89449.1 - 0.0072 16.2 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 SRR1 HeLo PF14479.1 GAP89452.1 - 2.5e-42 145.0 0.0 3.2e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation HET-s_218-289 PF11558.3 GAP89452.1 - 2.3e-06 27.4 0.2 4.9e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 Het-s 218-289 DUF3328 PF11807.3 GAP89453.1 - 1.5e-36 126.1 0.3 1.9e-36 125.7 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Pro_Al_protease PF02983.9 GAP89454.1 - 6.8e-05 22.7 1.5 6.8e-05 22.7 1.0 2.8 2 0 0 2 2 2 1 Alpha-lytic protease prodomain Ribosomal_S24e PF01282.14 GAP89455.1 - 3.5e-21 74.7 0.0 4.4e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S24e PhyH PF05721.8 GAP89456.1 - 9.8e-14 51.8 0.0 3.1e-13 50.2 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans PF04082.13 GAP89457.1 - 1.6e-22 79.6 0.0 2.7e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 GAP89458.1 - 2.6e-26 92.1 42.3 4.9e-26 91.2 28.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 GAP89459.1 - 3.5e-09 35.8 41.1 4.2e-09 35.5 27.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 GAP89459.1 - 9.2e-09 34.9 7.3 9.2e-09 34.9 5.1 2.4 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 BcrAD_BadFG PF01869.15 GAP89460.1 - 2.3e-22 79.6 0.7 7.8e-22 77.8 0.2 2.1 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family SIS_2 PF13580.1 GAP89460.1 - 4.7e-07 29.5 0.1 3.3e-06 26.8 0.0 2.5 2 1 0 2 2 2 1 SIS domain SIS PF01380.17 GAP89460.1 - 0.042 13.4 1.3 0.16 11.5 0.0 2.3 2 0 0 2 2 2 0 SIS domain Beta-lactamase PF00144.19 GAP89461.1 - 1.2e-51 175.7 0.3 1.7e-51 175.1 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase HET PF06985.6 GAP89462.1 - 2.1e-22 79.7 4.6 3.1e-19 69.5 0.3 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HRDC PF00570.18 GAP89463.1 - 0.011 15.4 0.6 17 5.2 0.0 3.5 3 0 0 3 3 3 0 HRDC domain Pkinase PF00069.20 GAP89464.1 - 1.3e-39 135.9 0.1 2.1e-39 135.2 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP89464.1 - 4.7e-20 71.7 0.1 6.6e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP89464.1 - 0.00024 20.1 0.0 0.00056 18.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like FHA PF00498.21 GAP89464.1 - 0.058 13.5 1.8 0.22 11.6 0.3 2.4 2 0 0 2 2 2 0 FHA domain DUF2095 PF09868.4 GAP89464.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) IBR PF01485.16 GAP89465.1 - 1.4e-12 47.2 31.3 5.6e-08 32.5 7.1 4.9 4 2 0 4 4 4 2 IBR domain FAD_binding_1 PF00667.15 GAP89466.1 - 2.2e-60 203.8 0.0 4.2e-60 202.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 GAP89466.1 - 3.3e-11 43.7 0.0 1.1e-10 42.0 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 GAP89466.1 - 1.3e-07 31.7 0.0 2.8e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Cupin_1 PF00190.17 GAP89467.1 - 2e-28 98.6 0.0 1.6e-15 56.8 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 GAP89467.1 - 7.1e-21 73.4 1.1 3.3e-11 42.5 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 GAP89467.1 - 2.9e-06 26.5 0.0 0.012 15.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.2 GAP89467.1 - 0.00044 19.9 0.0 0.21 11.1 0.0 2.9 2 1 1 3 3 3 2 Cupin Pkinase PF00069.20 GAP89468.1 - 2.9e-19 69.2 0.0 3.9e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 GAP89468.1 - 9.6e-05 22.2 0.1 0.094 12.4 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 GAP89468.1 - 0.00069 18.7 0.0 0.00082 18.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase SAE2 PF08573.5 GAP89469.1 - 0.083 13.6 5.7 0.14 12.9 2.9 2.1 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Zn_clus PF00172.13 GAP89470.1 - 5.3e-07 29.4 13.4 8.3e-07 28.8 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_43 PF04616.9 GAP89472.1 - 9.8e-37 126.5 7.2 1.2e-36 126.2 5.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_62 PF03664.8 GAP89472.1 - 0.038 13.1 4.5 0.039 13.0 2.0 1.6 1 1 1 2 2 2 0 Glycosyl hydrolase family 62 RCC1 PF00415.13 GAP89474.1 - 5.1e-56 186.6 4.8 4.6e-08 33.1 0.0 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAP89474.1 - 2.3e-28 97.1 32.8 1.6e-07 30.7 0.8 6.6 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Beta-lactamase PF00144.19 GAP89475.1 - 7.9e-30 103.9 1.5 1.1e-27 96.9 0.0 3.2 2 2 0 2 2 2 1 Beta-lactamase ADH_N PF08240.7 GAP89477.1 - 7.6e-32 109.3 0.0 1.9e-31 108.0 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAP89477.1 - 4.2e-15 55.4 0.1 2.6e-14 52.8 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAP89477.1 - 2.7e-05 25.0 0.0 6.3e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 GAP89477.1 - 0.022 14.3 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 GAP89477.1 - 0.03 13.4 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_16 PF10294.4 GAP89477.1 - 0.038 13.4 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase 3HCDH_N PF02737.13 GAP89477.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Patatin PF01734.17 GAP89478.1 - 1.9e-22 80.2 0.0 3.6e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase ABC_tran PF00005.22 GAP89478.1 - 0.00077 19.7 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter zf-B_box PF00643.19 GAP89478.1 - 0.0056 16.5 15.6 0.011 15.5 3.7 2.6 2 0 0 2 2 2 1 B-box zinc finger DUF258 PF03193.11 GAP89478.1 - 0.013 14.6 0.0 0.031 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 GAP89478.1 - 0.015 14.4 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Linker_histone PF00538.14 GAP89478.1 - 0.017 15.2 0.0 3.4 7.8 0.0 2.6 2 0 0 2 2 2 0 linker histone H1 and H5 family MMR_HSR1 PF01926.18 GAP89478.1 - 0.056 13.3 0.0 0.16 11.9 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 GAP89478.1 - 0.067 12.9 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B EFG_C PF00679.19 GAP89478.1 - 0.12 12.2 0.0 2.9 7.8 0.0 2.4 2 0 0 2 2 2 0 Elongation factor G C-terminus PriCT_2 PF08707.6 GAP89478.1 - 0.12 12.2 0.1 0.37 10.7 0.1 1.8 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) AAA_29 PF13555.1 GAP89478.1 - 0.12 11.8 0.1 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 GAP89478.1 - 0.19 11.6 0.6 0.97 9.3 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain NUP PF06516.6 GAP89479.1 - 7e-98 327.3 0.0 8.1e-98 327.1 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Glyco_hydro_43 PF04616.9 GAP89480.1 - 3.5e-40 137.9 0.8 3.9e-40 137.7 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Abhydrolase_6 PF12697.2 GAP89481.1 - 2.2e-23 83.3 0.1 2.7e-23 83.0 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP89481.1 - 1.4e-10 41.0 0.0 2.1e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAP89481.1 - 0.04 13.7 0.0 0.15 11.8 0.0 2.1 1 1 1 2 2 2 0 Putative lysophospholipase Glyco_hydro_28 PF00295.12 GAP89484.1 - 2.9e-96 322.2 18.0 3.4e-96 322.0 12.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 GAP89484.1 - 0.00052 19.8 31.9 0.0082 15.9 22.1 2.4 1 1 0 1 1 1 1 Right handed beta helix region Sugar_tr PF00083.19 GAP89485.1 - 1.8e-96 323.4 18.2 4.2e-96 322.2 12.6 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP89485.1 - 1.1e-18 67.1 19.6 1.1e-18 67.1 13.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 GAP89485.1 - 1.2 8.5 11.6 4.3 6.8 0.1 3.4 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 PAP_assoc PF03828.14 GAP89487.1 - 1.3e-14 53.8 0.0 2.6e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 GAP89487.1 - 1.1e-06 28.8 0.0 2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain SNF2_N PF00176.18 GAP89489.1 - 3.3e-13 49.1 0.0 2.8e-12 46.0 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain DNA_methylase PF00145.12 GAP89489.1 - 6.2e-10 38.7 0.0 1.1e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase Ureidogly_hydro PF04115.7 GAP89490.1 - 1.8e-46 157.5 0.0 2.3e-46 157.1 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase Peptidase_C48 PF02902.14 GAP89491.1 - 3.4e-06 26.8 1.5 0.029 13.9 0.0 2.6 3 0 0 3 3 3 2 Ulp1 protease family, C-terminal catalytic domain UbiA PF01040.13 GAP89492.1 - 4.6e-20 71.9 12.8 6e-20 71.5 8.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Git3 PF11710.3 GAP89494.1 - 9e-10 38.4 4.6 3.9e-09 36.3 3.2 1.9 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 GAP89494.1 - 4.4e-08 32.5 3.9 8e-08 31.7 2.7 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 GAP89494.1 - 0.0028 16.6 4.9 0.0049 15.8 3.4 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3_C PF11970.3 GAP89494.1 - 0.0039 16.9 0.1 0.0039 16.9 0.1 2.3 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term MFS_1 PF07690.11 GAP89496.1 - 5.8e-19 68.0 44.1 1.2e-18 66.9 29.7 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily MRC1 PF09444.5 GAP89499.1 - 1.8e-41 141.8 15.3 1.8e-41 141.8 10.6 6.8 5 1 1 6 6 6 1 MRC1-like domain SAGA-Tad1 PF12767.2 GAP89500.1 - 1e-53 182.6 0.0 1.3e-53 182.2 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Spc97_Spc98 PF04130.8 GAP89501.1 - 1e-114 383.8 0.1 1.4e-114 383.4 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Pkinase PF00069.20 GAP89502.1 - 2.9e-43 147.8 0.0 2.8e-42 144.6 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP89502.1 - 2.5e-27 95.6 0.0 5.5e-27 94.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP89502.1 - 0.0064 15.4 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like 1-cysPrx_C PF10417.4 GAP89502.1 - 0.027 14.1 0.5 0.074 12.7 0.4 1.7 1 0 0 1 1 1 0 C-terminal domain of 1-Cys peroxiredoxin Pox_ser-thr_kin PF05445.6 GAP89502.1 - 0.95 8.1 0.0 1.4 7.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase BTB PF00651.26 GAP89503.1 - 3.6e-13 49.4 0.0 6.4e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain HDNR PF15115.1 GAP89503.1 - 0.0044 16.9 0.1 0.0068 16.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function with conserved HDNR motif SDA1 PF05285.7 GAP89503.1 - 0.016 14.5 1.6 0.019 14.2 1.1 1.1 1 0 0 1 1 1 0 SDA1 YL1 PF05764.8 GAP89503.1 - 6.3 6.3 7.0 9.3 5.7 4.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DUF347 PF03988.7 GAP89504.1 - 0.074 12.9 0.2 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Aminotran_4 PF01063.14 GAP89505.1 - 1.7e-24 86.5 0.0 2.2e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV IgaA PF07095.6 GAP89506.1 - 0.0023 15.7 0.3 0.0033 15.2 0.2 1.1 1 0 0 1 1 1 1 Intracellular growth attenuator protein IgaA CENP-U PF13097.1 GAP89506.1 - 0.0084 16.0 1.9 0.018 15.0 1.3 1.5 1 0 0 1 1 1 1 CENP-A nucleosome associated complex (NAC) subunit Ldh_1_C PF02866.13 GAP89506.1 - 0.045 13.4 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain Peptidase_M75 PF09375.5 GAP89506.1 - 0.068 12.4 3.9 0.085 12.1 0.2 2.2 2 1 0 2 2 2 0 Imelysin COG5 PF10392.4 GAP89506.1 - 0.12 12.3 7.1 0.43 10.5 0.2 3.1 1 1 2 3 3 3 0 Golgi transport complex subunit 5 Lipoprotein_6 PF01441.14 GAP89506.1 - 0.22 11.3 4.5 2.8 7.7 0.1 2.3 2 1 0 2 2 2 0 Lipoprotein COMPASS-Shg1 PF05205.7 GAP89506.1 - 0.86 9.9 7.1 5 7.4 4.3 2.2 1 1 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 DUF4239 PF14023.1 GAP89506.1 - 1.9 7.7 3.9 0.8 9.0 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) DUF1640 PF07798.6 GAP89506.1 - 2.8 7.9 7.7 2.4 8.1 1.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) His_Phos_1 PF00300.17 GAP89507.1 - 3.3e-23 82.5 0.0 4.5e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 GAP89507.1 - 0.07 12.4 0.0 0.079 12.2 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) ERG4_ERG24 PF01222.12 GAP89508.1 - 1.8e-142 474.8 20.2 2.1e-142 474.6 14.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DNA_pol_E_B PF04042.11 GAP89509.1 - 8.9e-60 201.5 0.0 1.3e-59 201.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pkinase PF00069.20 GAP89511.1 - 3.5e-77 259.0 0.0 4.9e-77 258.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP89511.1 - 8.4e-39 133.1 0.0 1.3e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 GAP89511.1 - 5.4e-16 58.5 0.4 1.9e-15 56.7 0.3 2.0 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 GAP89511.1 - 1.5e-07 30.7 0.0 8.8e-07 28.1 0.0 1.9 1 1 0 2 2 2 1 Kinase-like YukC PF10140.4 GAP89511.1 - 0.011 14.3 0.0 0.017 13.7 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 GAP89511.1 - 0.055 13.2 0.4 0.38 10.4 0.1 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF4596 PF15363.1 GAP89511.1 - 0.32 10.9 2.4 0.73 9.8 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) NAD_binding_6 PF08030.7 GAP89512.1 - 1.6e-23 83.3 0.0 2.4e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 GAP89512.1 - 3.3e-13 49.4 0.0 9.9e-13 47.8 0.0 1.9 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 GAP89512.1 - 2.3e-12 47.0 14.3 2.3e-12 47.0 9.9 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 GAP89512.1 - 0.014 15.9 0.0 3 8.4 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF1212 PF06738.7 GAP89512.1 - 3.7 6.9 10.7 0.058 12.8 1.7 2.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1212) DivIC PF04977.10 GAP89513.1 - 0.17 11.3 29.3 0.17 11.4 1.9 6.7 4 1 3 7 7 7 0 Septum formation initiator bZIP_1 PF00170.16 GAP89513.1 - 1.6 8.7 16.2 2.4 8.1 0.2 4.9 2 1 2 5 5 5 0 bZIP transcription factor FlxA PF14282.1 GAP89513.1 - 2.6 8.0 23.0 5.5 6.9 0.5 5.1 4 1 0 5 5 5 0 FlxA-like protein Dioxygenase_C PF00775.16 GAP89514.1 - 8.9e-09 34.8 0.0 2.1e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 Dioxygenase Dioxygenase_C PF00775.16 GAP89515.1 - 3e-12 46.1 2.8 2.5e-11 43.1 1.9 2.1 1 1 0 1 1 1 1 Dioxygenase RTA1 PF04479.8 GAP89516.1 - 1.5e-26 93.3 7.2 2.2e-26 92.7 5.0 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF1180 PF06679.7 GAP89516.1 - 4.1 7.2 7.6 1.8 8.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) Fork_head PF00250.13 GAP89518.1 - 1.3e-11 44.3 0.0 2.6e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 GAP89518.1 - 4.8e-05 23.3 0.0 0.0001 22.3 0.0 1.5 1 0 0 1 1 1 1 FHA domain IFRD PF05004.8 GAP89520.1 - 2.1e-33 115.7 1.1 2.9e-33 115.2 0.7 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.1 GAP89520.1 - 0.0003 21.0 0.1 0.029 14.6 0.0 2.5 1 1 1 2 2 2 1 HEAT repeats MMS19_C PF12460.3 GAP89520.1 - 0.013 14.2 0.2 0.14 10.8 0.0 2.2 2 1 0 2 2 2 0 RNAPII transcription regulator C-terminal Ferrochelatase PF00762.14 GAP89520.1 - 0.05 12.5 0.1 1.9 7.3 0.1 2.5 2 1 0 2 2 2 0 Ferrochelatase UNC45-central PF11701.3 GAP89520.1 - 0.12 12.0 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central FHA PF00498.21 GAP89521.1 - 1.6e-09 37.7 0.0 3.9e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 FHA domain WD40 PF00400.27 GAP89522.1 - 2.2e-46 154.1 21.0 3e-11 42.7 0.0 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 GAP89522.1 - 5.2e-05 21.5 6.5 0.68 7.9 0.0 4.8 2 1 1 4 4 4 3 Nucleoporin Nup120/160 DUF1513 PF07433.6 GAP89522.1 - 0.0015 17.5 1.0 5.5 5.7 0.0 3.4 2 1 2 4 4 4 3 Protein of unknown function (DUF1513) Nucleoporin_N PF08801.6 GAP89522.1 - 0.028 13.1 0.3 0.86 8.2 0.2 2.9 1 1 0 1 1 1 0 Nup133 N terminal like DUF3312 PF11768.3 GAP89522.1 - 0.028 12.6 0.0 0.062 11.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3312) Hira PF07569.6 GAP89522.1 - 0.053 12.7 1.4 9.8 5.3 0.0 2.9 1 1 2 3 3 3 0 TUP1-like enhancer of split HEAT PF02985.17 GAP89523.1 - 1.4e-10 40.3 0.3 0.052 13.6 0.0 5.4 5 0 0 5 5 5 3 HEAT repeat Pkinase_Tyr PF07714.12 GAP89523.1 - 2.7e-07 29.9 0.0 4.7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAP89523.1 - 5.1e-07 29.0 0.0 9.6e-07 28.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HEAT_EZ PF13513.1 GAP89523.1 - 2.4e-05 24.6 0.0 0.17 12.3 0.0 3.0 2 0 0 2 2 2 2 HEAT-like repeat HEAT_2 PF13646.1 GAP89523.1 - 8e-05 22.8 0.2 0.0072 16.5 0.0 3.0 2 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.2 GAP89523.1 - 0.019 14.8 0.0 0.043 13.6 0.0 1.5 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Kinase-like PF14531.1 GAP89523.1 - 0.039 12.8 0.0 0.065 12.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Ipi1_N PF12333.3 GAP89523.1 - 0.068 13.1 0.0 0.76 9.7 0.0 2.4 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation FAD_binding_4 PF01565.18 GAP89524.1 - 2.6e-24 85.2 0.2 4.4e-24 84.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain GHMP_kinases_N PF00288.21 GAP89525.1 - 1e-11 44.6 0.0 2.2e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 GAP89525.1 - 6.2e-06 26.3 0.0 6.2e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 GHMP kinases C terminal Hexapep PF00132.19 GAP89526.1 - 1.8e-13 49.3 18.5 8.9e-07 28.1 2.8 3.2 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 GAP89526.1 - 3.6e-13 48.8 16.2 1.1e-08 34.4 3.9 2.6 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 GAP89526.1 - 1.2e-09 38.0 0.0 1.2e-09 38.0 0.0 2.3 2 0 0 2 2 2 1 Maltose acetyltransferase Zn_clus PF00172.13 GAP89526.1 - 3e-09 36.6 8.8 6.2e-09 35.6 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIP-T3 PF10243.4 GAP89526.1 - 0.12 10.7 19.4 0.16 10.3 13.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 ADH_zinc_N PF00107.21 GAP89528.1 - 4.4e-11 42.4 0.6 9.7e-11 41.3 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP89528.1 - 1.4e-05 24.8 0.0 3.9e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NmrA PF05368.8 GAP89528.1 - 0.0025 17.1 0.3 0.0041 16.4 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAP89528.1 - 0.0089 16.0 0.7 0.016 15.2 0.1 1.6 2 0 0 2 2 2 1 NADH(P)-binding Fungal_trans PF04082.13 GAP89529.1 - 4.4e-21 74.9 2.5 7.6e-21 74.1 1.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP89529.1 - 2.9e-08 33.4 9.3 2.9e-08 33.4 6.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIOX_N PF14226.1 GAP89530.1 - 2.4e-27 95.7 0.0 4e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAP89530.1 - 9e-20 70.8 0.0 1.5e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AIM24 PF01987.12 GAP89531.1 - 1.6e-49 168.2 0.2 2.1e-49 167.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Fungal_trans_2 PF11951.3 GAP89532.1 - 1.5e-05 23.7 0.6 1.5e-05 23.7 0.4 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP89532.1 - 2.9e-05 23.8 2.2 2.9e-05 23.8 1.5 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L14e PF01929.12 GAP89532.1 - 0.12 12.7 0.6 0.29 11.4 0.4 1.7 1 0 0 1 1 1 0 Ribosomal protein L14 WAK_assoc PF14380.1 GAP89532.1 - 1.3 9.5 4.9 2.3 8.7 2.8 1.9 2 0 0 2 2 2 0 Wall-associated receptor kinase C-terminal PAM2 PF07145.10 GAP89533.1 - 0.054 13.0 0.1 0.13 11.8 0.1 1.7 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Med1 PF10744.4 GAP89534.1 - 4.4e-28 98.1 0.0 3.3e-27 95.2 0.0 2.2 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Mitofilin PF09731.4 GAP89536.1 - 0.11 11.0 10.1 0.15 10.7 7.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Dicty_REP PF05086.7 GAP89536.1 - 0.44 8.2 12.6 0.57 7.8 8.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Macoilin PF09726.4 GAP89536.1 - 7.5 4.7 6.3 10 4.2 4.3 1.1 1 0 0 1 1 1 0 Transmembrane protein IER PF05760.7 GAP89536.1 - 8.4 6.2 12.9 12 5.7 8.9 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) NmrA PF05368.8 GAP89537.1 - 8.6e-15 54.6 0.4 3.4e-13 49.3 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 GAP89537.1 - 2.1e-11 44.1 3.8 2.5e-11 43.9 0.4 2.4 2 1 0 2 2 2 1 NADH(P)-binding Serglycin PF04360.7 GAP89537.1 - 0.011 15.4 1.0 0.019 14.7 0.7 1.3 1 0 0 1 1 1 0 Serglycin Patatin PF01734.17 GAP89538.1 - 4.4e-19 69.2 0.2 1.3e-18 67.7 0.0 1.7 2 0 0 2 2 2 1 Patatin-like phospholipase Gln-synt_C PF00120.19 GAP89542.1 - 5.3e-62 209.3 0.0 6.3e-62 209.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 GAP89542.1 - 9.5e-20 69.9 0.0 1.9e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain MOSC PF03473.12 GAP89544.1 - 3.4e-20 71.8 0.0 9.5e-20 70.4 0.0 1.8 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.22 GAP89544.1 - 1.1e-11 44.3 0.7 2.4e-11 43.1 0.5 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.16 GAP89544.1 - 1.2e-09 38.7 0.0 4.5e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 GAP89544.1 - 7.7e-05 22.7 0.0 0.0002 21.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 GAP89544.1 - 0.15 11.9 0.6 5.1 6.9 0.1 2.5 1 1 0 2 2 2 0 Ferric reductase NAD binding domain adh_short PF00106.20 GAP89545.1 - 6e-20 71.8 0.7 1.2e-19 70.8 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP89545.1 - 3.7e-11 43.2 0.0 5.3e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAP89545.1 - 8e-10 39.0 0.2 2.1e-09 37.6 0.1 1.7 2 0 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 GAP89545.1 - 2.4e-05 24.0 1.0 5.7e-05 22.8 0.7 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 GAP89545.1 - 6.7e-05 22.4 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 GAP89545.1 - 0.0015 18.1 0.9 0.0074 15.9 0.1 2.2 2 1 0 2 2 2 1 KR domain DUF1776 PF08643.5 GAP89545.1 - 0.004 16.3 0.0 0.0057 15.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.8 GAP89545.1 - 0.094 11.9 0.0 0.49 9.6 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family DUF2064 PF09837.4 GAP89545.1 - 0.11 12.0 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) HMGL-like PF00682.14 GAP89546.1 - 2e-60 204.3 0.0 2.8e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 GAP89546.1 - 4.1e-22 78.3 0.0 9.4e-22 77.2 0.0 1.6 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain NAD_binding_10 PF13460.1 GAP89547.1 - 5.4e-11 42.8 0.4 2e-10 40.9 0.3 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAP89547.1 - 1.5e-09 37.6 0.1 6e-09 35.6 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAP89547.1 - 0.00031 19.5 0.0 0.0015 17.3 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 GAP89547.1 - 0.0062 15.8 0.1 0.0098 15.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 GAP89547.1 - 0.027 14.3 1.3 0.077 12.9 0.9 1.7 1 1 0 1 1 1 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 GAP89547.1 - 0.074 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ank_2 PF12796.2 GAP89549.1 - 1.1e-25 89.7 0.0 1.9e-09 37.7 0.0 4.4 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAP89549.1 - 1.9e-21 74.7 1.6 0.00039 20.0 0.0 7.9 6 1 1 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 GAP89549.1 - 6.2e-21 74.3 1.3 0.00065 20.1 0.0 6.8 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP89549.1 - 4.3e-17 61.7 5.5 1e-05 25.6 0.0 7.0 6 2 2 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP89549.1 - 4.6e-13 48.0 0.3 0.1 12.8 0.0 7.0 6 1 1 7 7 7 4 Ankyrin repeat Glt_symporter PF03616.9 GAP89549.1 - 0.023 13.1 0.0 0.034 12.6 0.0 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF1843 PF08898.5 GAP89549.1 - 0.031 14.3 0.9 10 6.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Phosphonate-bd PF12974.2 GAP89549.1 - 0.076 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein DUF3741 PF12552.3 GAP89549.1 - 0.083 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3741) Ank_2 PF12796.2 GAP89550.1 - 1.1e-52 176.2 3.2 4.4e-14 52.5 0.0 8.4 2 1 8 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 GAP89550.1 - 3.8e-29 99.0 18.0 0.00042 19.9 0.1 11.1 12 0 0 12 12 12 7 Ankyrin repeat Ank_4 PF13637.1 GAP89550.1 - 9.4e-26 89.7 8.1 3.8e-08 33.6 0.0 10.2 8 2 3 11 11 11 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP89550.1 - 4.1e-25 85.3 7.5 0.012 15.7 0.0 11.3 12 0 0 12 12 12 5 Ankyrin repeat Ank_5 PF13857.1 GAP89550.1 - 1.3e-15 57.0 9.6 0.024 14.9 0.0 8.7 6 2 4 10 10 10 4 Ankyrin repeats (many copies) Clr5 PF14420.1 GAP89550.1 - 0.00024 20.9 2.9 0.00045 20.0 2.0 1.5 1 0 0 1 1 1 1 Clr5 domain zf-C2H2 PF00096.21 GAP89551.1 - 0.014 15.7 3.3 0.014 15.7 2.3 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-Di19 PF05605.7 GAP89551.1 - 2.7 8.1 8.7 3.1 7.9 1.0 3.6 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding ADH_zinc_N PF00107.21 GAP89552.1 - 8.5e-22 77.0 0.4 1.1e-21 76.6 0.3 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAP89552.1 - 8.6e-20 71.9 0.5 1.4e-19 71.2 0.1 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase UPF0075 PF03702.9 GAP89552.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) DLH PF01738.13 GAP89553.1 - 1.9e-23 82.8 0.0 3.1e-21 75.6 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 GAP89553.1 - 1.6e-10 40.8 0.1 4.1e-10 39.5 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP89553.1 - 2.6e-05 24.1 0.0 0.015 15.1 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 GAP89553.1 - 0.028 13.9 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Rep_fac-A_C PF08646.5 GAP89554.1 - 7.4e-57 191.1 2.9 6.8e-55 184.7 0.4 2.3 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 GAP89554.1 - 5.6e-22 77.4 0.0 1.1e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 GAP89554.1 - 3.4e-17 62.0 0.5 2.3e-12 46.5 0.0 4.1 4 0 0 4 4 4 3 OB-fold nucleic acid binding domain DUF223 PF02721.9 GAP89554.1 - 0.0004 20.4 0.0 0.00085 19.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF223 zf-like PF04071.7 GAP89554.1 - 0.031 13.9 0.2 0.078 12.6 0.1 1.6 1 0 0 1 1 1 0 Cysteine-rich small domain PCI PF01399.22 GAP89555.1 - 0.00033 20.9 0.0 0.00072 19.8 0.0 1.6 1 0 0 1 1 1 1 PCI domain YfiO PF13525.1 GAP89555.1 - 0.021 14.3 0.0 0.049 13.1 0.0 1.6 1 0 0 1 1 1 0 Outer membrane lipoprotein TPR_2 PF07719.12 GAP89555.1 - 0.05 13.5 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Bac_rhodopsin PF01036.13 GAP89556.1 - 8.6e-47 159.2 19.6 1.1e-46 158.9 13.6 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Fusion_gly_K PF01621.12 GAP89556.1 - 0.0067 15.5 1.1 0.0094 15.0 0.7 1.2 1 0 0 1 1 1 1 Cell fusion glycoprotein K S_100 PF01023.14 GAP89556.1 - 0.14 11.4 0.1 0.26 10.6 0.1 1.4 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain DUF4131 PF13567.1 GAP89556.1 - 0.63 9.4 9.7 2.1 7.7 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) NACHT PF05729.7 GAP89557.1 - 5.3e-09 35.9 0.0 1.2e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAP89557.1 - 1.4e-05 25.2 0.0 7.4e-05 22.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAP89557.1 - 2.7e-05 24.2 0.0 8.3e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 GAP89557.1 - 0.0024 18.1 0.1 0.035 14.4 0.0 2.8 3 1 0 3 3 3 1 AAA domain AAA_10 PF12846.2 GAP89557.1 - 0.0054 16.2 0.0 0.014 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA-like domain AAA_17 PF13207.1 GAP89557.1 - 0.0062 17.3 0.0 0.041 14.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 GAP89557.1 - 0.011 15.8 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 GAP89557.1 - 0.014 15.3 0.0 0.041 13.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 GAP89557.1 - 0.03 13.8 0.0 0.074 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 GAP89557.1 - 0.032 14.1 0.0 0.09 12.7 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase KAP_NTPase PF07693.9 GAP89557.1 - 0.033 13.1 1.3 0.59 9.0 0.0 2.5 3 0 0 3 3 3 0 KAP family P-loop domain ABC_tran PF00005.22 GAP89557.1 - 0.051 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter T2SE PF00437.15 GAP89557.1 - 0.064 12.1 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 GAP89557.1 - 0.098 11.7 0.0 0.25 10.4 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin DUF258 PF03193.11 GAP89557.1 - 0.1 11.7 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF4116 PF13475.1 GAP89557.1 - 0.11 12.0 0.1 15 5.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) L27 PF02828.11 GAP89557.1 - 0.58 9.8 4.0 7 6.4 0.3 3.4 4 0 0 4 4 4 0 L27 domain 2Fe-2S_thioredx PF01257.14 GAP89558.1 - 7.7e-59 197.4 0.0 9.5e-59 197.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Kelch_5 PF13854.1 GAP89559.1 - 1.2e-15 57.0 0.2 0.0004 20.2 0.0 4.9 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.1 GAP89559.1 - 1.7e-15 56.6 21.9 8.5e-08 32.1 0.1 9.3 9 1 0 9 9 9 3 Galactose oxidase, central domain Kelch_4 PF13418.1 GAP89559.1 - 2e-14 53.0 9.5 5.6e-05 22.8 0.1 6.7 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_1 PF01344.20 GAP89559.1 - 8.7e-09 34.7 0.0 0.11 12.0 0.0 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 GAP89559.1 - 2.8e-08 33.5 5.4 0.024 14.7 0.0 5.0 5 1 1 6 6 5 3 Kelch motif Kelch_2 PF07646.10 GAP89559.1 - 1.9e-05 24.1 1.0 0.058 13.1 0.0 4.9 6 0 0 6 6 5 1 Kelch motif Nop14 PF04147.7 GAP89559.1 - 0.036 12.0 42.5 0.061 11.2 29.5 1.2 1 0 0 1 1 1 0 Nop14-like family DUF385 PF04075.9 GAP89559.1 - 0.048 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF385) Daxx PF03344.10 GAP89559.1 - 0.13 10.7 41.9 0.21 10.0 29.1 1.2 1 0 0 1 1 1 0 Daxx Family VSG_B PF13206.1 GAP89559.1 - 0.39 9.7 13.2 0.59 9.2 9.2 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain Zip PF02535.17 GAP89559.1 - 0.65 8.9 7.3 9.5 5.1 5.8 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter RR_TM4-6 PF06459.7 GAP89559.1 - 0.78 9.5 24.3 1.4 8.7 16.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 LMBR1 PF04791.11 GAP89559.1 - 1 7.8 4.0 1.3 7.5 2.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CytochromB561_N PF09786.4 GAP89559.1 - 2 6.7 3.8 2.8 6.2 2.6 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal CDC45 PF02724.9 GAP89559.1 - 2.3 6.1 33.9 3.4 5.5 23.5 1.1 1 0 0 1 1 1 0 CDC45-like protein PLRV_ORF5 PF01690.12 GAP89559.1 - 4.4 6.3 17.3 6.8 5.7 12.0 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF4011 PF13195.1 GAP89559.1 - 4.8 7.1 12.0 9.3 6.2 8.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Ycf1 PF05758.7 GAP89559.1 - 7.5 4.1 25.5 10 3.7 17.7 1.0 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 GAP89559.1 - 8.2 3.9 15.6 11 3.5 10.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-C2H2_4 PF13894.1 GAP89560.1 - 1.4e-07 31.3 49.9 0.0001 22.3 3.5 7.8 8 0 0 8 8 8 4 C2H2-type zinc finger zf-C2H2 PF00096.21 GAP89560.1 - 3.5e-05 23.8 58.2 0.00073 19.7 4.8 7.6 8 0 0 8 8 8 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 GAP89560.1 - 0.033 14.3 0.3 0.033 14.3 0.2 5.5 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAP89560.1 - 1.9 8.8 0.0 1.9 8.8 0.0 6.3 6 0 0 6 6 6 0 Zinc-finger of C2H2 type Cyt-b5 PF00173.23 GAP89561.1 - 8.4e-13 47.9 0.1 9.9e-13 47.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TPR_12 PF13424.1 GAP89562.1 - 1e-11 44.5 8.5 3.7e-05 23.5 0.1 4.0 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 GAP89562.1 - 3.3e-06 26.6 5.7 0.083 12.5 0.0 4.0 3 1 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 GAP89562.1 - 0.0011 18.7 4.1 0.29 11.1 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat RPN7 PF10602.4 GAP89562.1 - 0.0013 18.1 0.5 4.7 6.5 0.0 3.7 4 0 0 4 4 4 2 26S proteasome subunit RPN7 TPR_7 PF13176.1 GAP89562.1 - 0.0062 16.2 0.8 32 4.6 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAP89562.1 - 0.016 14.7 2.0 7.1 6.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat IgG_binding_B PF01378.12 GAP89562.1 - 0.19 11.5 0.3 0.38 10.5 0.2 1.5 1 0 0 1 1 1 0 B domain TPR_14 PF13428.1 GAP89562.1 - 4.5 8.1 8.2 33 5.4 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat zf-C2H2 PF00096.21 GAP89563.1 - 4.3e-05 23.6 12.9 0.018 15.3 0.2 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP89563.1 - 0.00067 19.8 20.9 0.072 13.4 1.0 5.0 4 1 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAP89563.1 - 0.1 12.7 1.8 20 5.4 0.4 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding SpoIIE PF07228.7 GAP89563.1 - 0.18 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) zf-met PF12874.2 GAP89563.1 - 0.28 11.4 2.3 26 5.2 0.5 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-TRAF PF02176.13 GAP89563.1 - 3.1 8.2 10.9 0.24 11.7 0.4 3.2 3 0 0 3 3 3 0 TRAF-type zinc finger FRG2 PF15315.1 GAP89563.1 - 6.7 6.6 10.6 18 5.2 3.9 2.3 2 0 0 2 2 2 0 Facioscapulohumeral muscular dystrophy candidate 2 TraV PF09676.5 GAP89564.1 - 0.24 12.1 3.1 0.15 12.7 0.2 2.0 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) p450 PF00067.17 GAP89566.1 - 6.3e-55 186.5 0.0 6.9e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_26 PF02156.10 GAP89566.1 - 0.012 15.0 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 26 TFCD_C PF12612.3 GAP89566.1 - 0.067 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal Amnionless PF14828.1 GAP89567.1 - 0.15 10.5 0.0 0.18 10.2 0.0 1.2 1 0 0 1 1 1 0 Amnionless Glycophorin_A PF01102.13 GAP89567.1 - 0.15 11.8 4.1 0.3 10.8 2.2 1.9 1 1 0 1 1 1 0 Glycophorin A ODC_AZ PF02100.12 GAP89568.1 - 5.9e-29 99.7 0.0 8.2e-29 99.2 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme His_biosynth PF00977.16 GAP89569.1 - 6.5e-50 169.5 0.1 2.6e-49 167.5 0.0 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 GAP89569.1 - 2.3e-27 95.7 0.0 3.4e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 GAP89569.1 - 2.9e-10 40.0 0.0 1.1e-09 38.1 0.0 1.8 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 GAP89569.1 - 9.1e-09 35.0 0.0 2.6e-08 33.6 0.0 1.8 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Dus PF01207.12 GAP89569.1 - 0.00098 18.0 0.1 0.0021 16.9 0.1 1.5 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Peptidase_C26 PF07722.8 GAP89569.1 - 0.0045 16.4 0.0 0.46 9.8 0.0 2.3 2 0 0 2 2 2 2 Peptidase C26 TFIIIC_sub6 PF10419.4 GAP89570.1 - 1.5e-06 27.5 0.0 3.7e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 TFIIIC subunit RNA_Me_trans PF04252.8 GAP89571.1 - 8.5e-26 90.5 0.0 9.6e-26 90.3 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase RNA_Me_trans PF04252.8 GAP89572.1 - 0.048 13.0 0.0 0.048 13.0 0.0 1.1 1 0 0 1 1 1 0 Predicted SAM-dependent RNA methyltransferase Ino80_Iec3 PF14612.1 GAP89573.1 - 1.5e-58 198.5 8.0 1e-31 110.8 3.6 2.3 1 1 1 2 2 2 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling UPF0160 PF03690.8 GAP89574.1 - 7e-117 390.3 0.0 8e-117 390.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Endosulfine PF04667.12 GAP89575.1 - 3.4e-21 75.0 0.1 6.4e-21 74.1 0.1 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Herpes_capsid PF06112.6 GAP89575.1 - 3.1 7.8 6.0 4.2 7.4 4.2 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Sugar_tr PF00083.19 GAP89577.1 - 1e-87 294.6 20.5 1.3e-87 294.2 14.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP89577.1 - 9.8e-23 80.4 37.6 2.3e-16 59.4 8.0 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF946 PF06101.6 GAP89577.1 - 1.1e-10 40.1 0.2 1.1e-10 40.1 0.1 1.5 2 0 0 2 2 2 1 Plant protein of unknown function (DUF946) Acetyltransf_7 PF13508.1 GAP89578.1 - 2.8e-07 30.6 0.0 4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAP89578.1 - 7.1e-07 28.9 0.0 9.4e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.19 GAP89578.1 - 2.9e-06 27.1 0.1 3.9e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAP89578.1 - 0.0013 18.8 0.0 0.0016 18.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Esterase_phd PF10503.4 GAP89579.1 - 1.5e-20 73.3 0.2 2.1e-20 72.9 0.1 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 GAP89579.1 - 2.4e-11 43.2 0.4 3.3e-11 42.8 0.3 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAP89579.1 - 0.00018 21.3 0.1 0.00025 20.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 GAP89579.1 - 0.0011 17.7 0.1 0.0016 17.2 0.1 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAP89579.1 - 0.0084 15.7 0.1 0.019 14.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAP89579.1 - 0.033 14.0 0.3 0.1 12.4 0.2 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP89579.1 - 0.079 12.5 0.1 0.13 11.8 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Ank_3 PF13606.1 GAP89581.1 - 2.2e-06 27.3 0.0 0.014 15.6 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 GAP89581.1 - 7.3e-06 25.5 0.0 0.00022 20.8 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 GAP89581.1 - 7.9e-06 26.1 0.0 0.0016 18.7 0.0 3.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAP89581.1 - 0.027 14.7 3.6 11 6.4 0.0 4.8 5 0 0 5 5 5 0 Ankyrin repeats (many copies) FCH PF00611.18 GAP89582.1 - 4.2e-21 74.9 0.0 4.2e-21 74.9 0.0 3.3 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 GAP89582.1 - 2.6e-18 65.3 0.4 9.6e-13 47.5 0.0 2.8 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 GAP89582.1 - 2.5e-15 55.5 0.1 1.8e-06 27.2 0.0 2.5 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.17 GAP89582.1 - 1.4e-14 53.5 5.6 2.1e-14 52.9 3.9 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_2 PF07653.12 GAP89582.1 - 0.00019 20.8 0.1 0.51 9.8 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain Spc7 PF08317.6 GAP89582.1 - 0.0029 16.3 13.6 0.22 10.1 0.2 2.3 2 0 0 2 2 2 2 Spc7 kinetochore protein SH3_3 PF08239.6 GAP89582.1 - 0.0066 16.6 0.9 0.36 11.0 0.2 2.4 2 0 0 2 2 2 1 Bacterial SH3 domain 7TM_GPCR_Sri PF10327.4 GAP89582.1 - 0.056 12.3 0.1 0.085 11.8 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri Spo12 PF05032.7 GAP89582.1 - 0.14 11.7 2.6 0.45 10.1 1.8 1.8 1 0 0 1 1 1 0 Spo12 family DUF2894 PF11445.3 GAP89582.1 - 0.15 12.2 9.0 0.058 13.6 2.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) C1_2 PF03107.11 GAP89582.1 - 0.55 10.3 7.8 0.96 9.6 5.4 1.4 1 0 0 1 1 1 0 C1 domain Tup_N PF08581.5 GAP89582.1 - 1.8 8.8 14.3 0.051 13.7 3.2 2.8 3 0 0 3 3 2 0 Tup N-terminal DUF4407 PF14362.1 GAP89582.1 - 1.9 7.3 9.0 0.44 9.4 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Allexi_40kDa PF05549.6 GAP89582.1 - 1.9 7.6 9.0 0.31 10.2 0.3 2.5 2 1 0 2 2 2 0 Allexivirus 40kDa protein IncA PF04156.9 GAP89582.1 - 2.3 7.7 14.5 1 8.8 3.5 2.6 2 0 0 2 2 2 0 IncA protein COG2 PF06148.6 GAP89582.1 - 4.5 7.1 12.9 4.1 7.2 2.0 2.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 SET PF00856.23 GAP89583.1 - 2.9e-11 43.9 0.1 3.3e-10 40.4 0.1 2.4 1 1 0 1 1 1 1 SET domain CBM_1 PF00734.13 GAP89583.1 - 0.018 14.6 0.9 0.043 13.4 0.6 1.6 1 0 0 1 1 1 0 Fungal cellulose binding domain DUF3774 PF12609.3 GAP89583.1 - 0.077 13.8 0.5 0.25 12.2 0.4 1.9 1 0 0 1 1 1 0 Wound-induced protein Basic PF01586.11 GAP89583.1 - 0.079 13.6 0.3 0.21 12.3 0.2 1.7 1 0 0 1 1 1 0 Myogenic Basic domain Glyco_hydro_72 PF03198.9 GAP89584.1 - 7.6e-125 416.0 1.3 8.9e-125 415.8 0.9 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 GAP89584.1 - 2.1e-05 23.9 0.6 0.0002 20.6 0.4 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TauD PF02668.11 GAP89585.1 - 2.1e-43 148.8 0.2 2.7e-43 148.4 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family But2 PF09792.4 GAP89586.1 - 3.5e-05 23.5 0.4 0.00034 20.3 0.0 2.5 2 1 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain SNF2_N PF00176.18 GAP89587.1 - 1.9e-52 177.9 0.0 3.1e-52 177.2 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 GAP89587.1 - 3.7e-22 77.9 0.1 9.3e-22 76.7 0.1 1.7 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 GAP89587.1 - 2.6e-14 52.8 0.0 3.8e-13 49.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAP89587.1 - 0.0038 17.0 0.0 0.09 12.5 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit GTP_EFTU PF00009.22 GAP89588.1 - 1.2e-49 168.3 0.0 2.1e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 GAP89588.1 - 2.6e-39 133.4 6.5 4.3e-39 132.7 4.5 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 GAP89588.1 - 2e-18 66.0 0.0 4.3e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.18 GAP89588.1 - 1.6e-05 24.8 0.0 3.8e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 GAP89588.1 - 2.2e-05 23.9 0.0 7.6e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Ras family EFG_II PF14492.1 GAP89588.1 - 2.3e-05 24.1 0.0 7.1e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 GAP89588.1 - 2.5e-05 24.2 0.1 6.7e-05 22.9 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.5 GAP89588.1 - 0.0091 15.2 0.0 0.024 13.8 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MR_MLE_C PF13378.1 GAP89589.1 - 6.9e-32 109.7 0.1 8.1e-31 106.2 0.0 2.3 2 1 1 3 3 3 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 GAP89589.1 - 3.4e-20 72.1 0.0 6.8e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 GAP89589.1 - 1.8e-08 34.7 0.0 4.8e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain adh_short PF00106.20 GAP89590.1 - 1.7e-30 106.1 4.8 2.9e-30 105.3 3.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP89590.1 - 1.9e-20 73.6 0.0 2.3e-20 73.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP89590.1 - 6.9e-14 51.9 4.4 1.1e-13 51.2 3.1 1.3 1 0 0 1 1 1 1 KR domain Glyco_trans_4_4 PF13579.1 GAP89590.1 - 0.0012 19.0 6.2 0.79 9.8 0.3 3.1 3 0 0 3 3 3 2 Glycosyl transferase 4-like domain Epimerase PF01370.16 GAP89590.1 - 0.0019 17.6 0.1 0.0028 17.1 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PALP PF00291.20 GAP89590.1 - 0.0069 15.6 0.1 0.011 14.9 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Glyco_transf_5 PF08323.6 GAP89590.1 - 0.027 13.9 0.3 0.12 11.7 0.0 2.0 2 1 0 2 2 2 0 Starch synthase catalytic domain Toprim_3 PF13362.1 GAP89590.1 - 0.052 13.7 0.3 0.96 9.7 0.0 2.5 2 1 0 2 2 2 0 Toprim domain Eno-Rase_NADH_b PF12242.3 GAP89590.1 - 0.066 13.0 0.3 0.066 13.0 0.2 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 GAP89590.1 - 0.23 11.4 3.3 3 7.8 2.3 2.5 1 1 0 1 1 1 0 NADH(P)-binding DHDPS PF00701.17 GAP89591.1 - 6e-44 149.7 0.0 7.4e-44 149.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family FMN_dh PF01070.13 GAP89592.1 - 4e-108 361.4 0.1 6.9e-108 360.6 0.1 1.3 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 GAP89592.1 - 5.2e-20 71.0 0.0 1.6e-19 69.4 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 GAP89592.1 - 7e-08 31.7 0.0 1.4e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 GAP89592.1 - 0.00034 19.6 0.8 0.0018 17.2 0.1 2.3 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 GAP89592.1 - 0.0015 17.7 0.2 0.0026 16.9 0.2 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_syn_central PF04898.9 GAP89592.1 - 0.049 12.8 0.0 0.075 12.2 0.0 1.3 1 0 0 1 1 1 0 Glutamate synthase central domain ThiG PF05690.9 GAP89592.1 - 0.4 9.7 3.1 2.4 7.1 0.1 2.6 3 0 0 3 3 3 0 Thiazole biosynthesis protein ThiG ApbA_C PF08546.6 GAP89593.1 - 3.6e-30 104.5 0.0 5.1e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 GAP89593.1 - 1.7e-26 92.4 0.0 1.4e-23 83.0 0.0 2.2 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA Aldo_ket_red PF00248.16 GAP89594.1 - 2.2e-59 200.6 0.0 2.8e-59 200.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ATP-synt_F PF01990.12 GAP89594.1 - 0.065 13.6 0.3 3.2 8.1 0.0 2.9 3 0 0 3 3 3 0 ATP synthase (F/14-kDa) subunit Glyco_transf_90 PF05686.7 GAP89595.1 - 4.2e-15 55.3 9.0 7.3e-13 47.9 5.6 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 90 Ribosomal_L7Ae PF01248.21 GAP89596.1 - 1.8e-28 97.8 0.9 2.4e-28 97.4 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 GAP89596.1 - 0.065 12.8 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family TauD PF02668.11 GAP89597.1 - 3.1e-27 95.8 0.0 6.5e-27 94.8 0.0 1.5 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sugar_tr PF00083.19 GAP89598.1 - 2.3e-77 260.4 19.6 2.6e-77 260.3 13.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP89598.1 - 2.2e-24 85.8 25.8 2.2e-24 85.8 17.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAP89598.1 - 2.3e-07 29.5 26.0 7.9e-05 21.2 4.5 3.3 2 2 1 3 3 3 3 MFS/sugar transport protein DUF3712 PF12505.3 GAP89599.1 - 1.4e-27 96.1 1.1 2.6e-27 95.3 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) QCR10 PF09796.4 GAP89599.1 - 0.11 12.2 0.3 0.24 11.1 0.2 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Ret_tiss PF10044.4 GAP89600.1 - 1.2e-05 25.7 3.3 22 5.6 0.0 7.1 4 2 5 9 9 9 0 Retinal tissue protein DUF3375 PF11855.3 GAP89600.1 - 0.0042 15.9 0.1 7.4 5.1 0.0 3.9 2 1 1 4 4 4 1 Protein of unknown function (DUF3375) Adaptin_N PF01602.15 GAP89600.1 - 0.0079 14.5 0.4 1.1 7.5 0.0 3.3 3 1 0 3 3 3 1 Adaptin N terminal region Proteasom_Rpn13 PF04683.8 GAP89600.1 - 0.06 13.4 0.0 38 4.4 0.0 4.4 6 0 0 6 6 6 0 Proteasome complex subunit Rpn13 ubiquitin receptor MIF4G PF02854.14 GAP89600.1 - 0.36 10.2 9.3 3.4 7.0 0.1 4.7 5 1 1 6 6 6 0 MIF4G domain RPW8 PF05659.6 GAP89600.1 - 3 7.3 7.2 18 4.8 0.0 5.1 4 3 4 8 8 8 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Period_C PF12114.3 GAP89600.1 - 6.9 6.2 10.5 11 5.5 7.3 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region SAD_SRA PF02182.12 GAP89601.1 - 1.2e-06 27.9 0.1 1.6e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 SAD/SRA domain TruD PF01142.13 GAP89602.1 - 1.1e-53 182.2 0.0 2.7e-49 167.8 0.0 3.5 3 1 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) Helicase_C_3 PF13625.1 GAP89603.1 - 2.7e-28 98.3 0.0 6.1e-27 93.9 0.0 3.0 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAP89603.1 - 7.2e-13 48.7 0.0 1.6e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 GAP89603.1 - 4.2e-10 38.9 0.0 7.3e-10 38.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAP89603.1 - 3e-08 33.3 0.0 6.5e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DHOase PF12890.2 GAP89603.1 - 0.011 15.3 0.1 0.049 13.3 0.0 2.0 2 0 0 2 2 2 0 Dihydro-orotase-like TrkH PF02386.11 GAP89604.1 - 6.9e-112 373.5 16.6 1e-111 373.0 7.2 2.1 2 0 0 2 2 2 2 Cation transport protein DUF1143 PF06608.6 GAP89604.1 - 0.016 15.1 0.3 0.034 14.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1143) Ribosomal_L19 PF01245.15 GAP89605.1 - 9e-18 64.1 0.0 1.4e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 PALP PF00291.20 GAP89607.1 - 2e-60 204.6 0.2 2.3e-60 204.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SH3_1 PF00018.23 GAP89608.1 - 7.4e-06 25.2 0.0 1.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAP89608.1 - 1.6e-05 24.4 0.1 4.1e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain ZZ PF00569.12 GAP89608.1 - 0.018 14.5 14.7 0.69 9.5 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, ZZ type Amino_oxidase PF01593.19 GAP89612.1 - 3.1e-36 125.4 1.0 7e-17 61.6 0.0 2.8 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAP89612.1 - 5.7e-15 55.0 0.1 1.2e-14 54.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAP89612.1 - 9.9e-06 25.8 0.0 1.9e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAP89612.1 - 1.8e-05 23.9 0.4 2.7e-05 23.4 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAP89612.1 - 4.9e-05 22.3 0.1 0.00059 18.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAP89612.1 - 0.00021 21.4 0.1 0.001 19.1 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAP89612.1 - 0.00031 19.7 0.6 0.00044 19.2 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 GAP89612.1 - 0.0013 18.6 0.3 0.0022 17.9 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAP89612.1 - 0.0017 16.8 0.1 0.0027 16.2 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein 3HCDH_N PF02737.13 GAP89612.1 - 0.0017 18.0 0.0 0.0031 17.1 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 GAP89612.1 - 0.0022 17.1 0.1 0.0039 16.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 GAP89612.1 - 0.0083 15.0 0.1 0.012 14.5 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 GAP89612.1 - 0.12 11.8 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 GAP89612.1 - 0.12 12.0 0.6 1 9.1 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding ECH PF00378.15 GAP89613.1 - 1e-67 227.8 0.1 1.3e-67 227.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DNA_pol_E_B PF04042.11 GAP89613.1 - 0.12 11.5 0.0 4.7 6.4 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase alpha/epsilon subunit B Rer1 PF03248.8 GAP89614.1 - 7.3e-81 269.9 5.6 8.3e-81 269.7 3.9 1.0 1 0 0 1 1 1 1 Rer1 family FA_desaturase PF00487.19 GAP89614.1 - 0.19 11.1 4.7 0.72 9.2 0.3 2.0 2 0 0 2 2 2 0 Fatty acid desaturase Paf1 PF03985.8 GAP89615.1 - 1.2e-54 185.7 0.3 1.5e-54 185.4 0.2 1.1 1 0 0 1 1 1 1 Paf1 Catalase PF00199.14 GAP89616.1 - 1.8e-148 494.3 3.2 1.2e-94 317.1 0.1 2.1 2 0 0 2 2 2 2 Catalase Catalase-rel PF06628.7 GAP89616.1 - 2.9e-13 49.4 0.1 6.5e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive RNA_polI_A14 PF08203.6 GAP89616.1 - 0.18 12.0 0.4 17 5.7 0.1 2.5 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 DUF3635 PF12330.3 GAP89617.1 - 2.6e-05 24.2 0.1 0.00017 21.6 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3635) APH PF01636.18 GAP89617.1 - 0.014 15.1 1.0 0.047 13.4 0.7 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF1857 PF08982.6 GAP89617.1 - 0.019 14.5 0.1 0.064 12.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1857) DUF1682 PF07946.9 GAP89618.1 - 4.8e-105 350.9 0.0 5.5e-105 350.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Tom37_C PF11801.3 GAP89618.1 - 0.44 10.3 4.8 0.98 9.2 3.3 1.5 1 0 0 1 1 1 0 Tom37 C-terminal domain DUF77 PF01910.12 GAP89619.1 - 1.4e-33 114.3 0.8 1.7e-33 114.1 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 Polysacc_deac_1 PF01522.16 GAP89619.1 - 0.01 15.4 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide deacetylase CDC37_N PF03234.9 GAP89621.1 - 1.7e-56 191.3 1.6 1.7e-56 191.3 0.2 1.7 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 GAP89621.1 - 2.6e-40 137.7 0.0 8.9e-40 135.9 0.0 1.8 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 GAP89621.1 - 1.2e-22 79.5 1.3 2.1e-22 78.8 0.1 2.0 2 0 0 2 2 2 1 Cdc37 C terminal domain DUF2762 PF10960.3 GAP89621.1 - 0.012 15.3 0.3 0.033 13.8 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) DUF1268 PF06896.6 GAP89621.1 - 0.025 14.9 0.7 0.14 12.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1268) Phage_GP20 PF06810.6 GAP89621.1 - 0.13 11.6 5.8 0.2 11.0 0.3 2.6 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF4407 PF14362.1 GAP89621.1 - 0.39 9.6 3.7 3.5 6.4 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) AIG2 PF06094.7 GAP89622.1 - 7.7e-06 26.3 0.0 1.4e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family SMC_N PF02463.14 GAP89623.1 - 5.9e-63 212.0 11.8 1.3e-62 210.9 8.2 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 GAP89623.1 - 3.2e-30 104.5 0.0 1.6e-29 102.3 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 GAP89623.1 - 2.9e-15 57.0 0.9 1.4e-06 28.5 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 GAP89623.1 - 1.3e-07 31.0 24.6 1.1e-06 27.9 0.9 3.8 2 2 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 GAP89623.1 - 2.4e-06 28.0 46.3 2.4e-06 28.0 32.1 7.2 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.1 GAP89623.1 - 0.00018 20.9 0.0 0.00044 19.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain IncA PF04156.9 GAP89623.1 - 0.0073 15.9 6.2 0.0073 15.9 4.3 7.7 4 2 2 8 8 8 2 IncA protein AAA_13 PF13166.1 GAP89623.1 - 0.059 11.8 0.0 0.059 11.8 0.0 6.2 3 2 3 6 6 6 0 AAA domain MMR_HSR1 PF01926.18 GAP89623.1 - 0.07 13.0 1.3 3.8 7.5 0.0 3.7 3 0 0 3 3 3 0 50S ribosome-binding GTPase DUF3535 PF12054.3 GAP89624.1 - 8.7e-131 436.5 0.2 1.3e-127 426.0 0.0 3.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 GAP89624.1 - 1.2e-72 244.2 0.0 1.9e-72 243.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 GAP89624.1 - 6.9e-18 63.0 2.0 0.0094 15.9 0.0 8.3 8 0 0 8 8 8 6 HEAT repeat Helicase_C PF00271.26 GAP89624.1 - 2.8e-14 52.7 0.0 6.4e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_2 PF13646.1 GAP89624.1 - 2.5e-07 30.8 6.0 0.0029 17.8 0.0 6.6 6 2 1 7 7 7 1 HEAT repeats HEAT_EZ PF13513.1 GAP89624.1 - 6.4e-07 29.6 6.6 4 8.0 0.0 8.5 9 0 0 9 9 9 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 GAP89624.1 - 5.4e-05 23.5 0.3 0.72 10.2 0.0 4.2 2 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 GAP89624.1 - 0.007 15.7 0.9 0.46 9.7 0.0 3.2 3 1 0 3 3 3 1 CLASP N terminal Zip PF02535.17 GAP89625.1 - 0.00052 19.1 5.3 0.00052 19.1 3.7 3.2 2 1 0 2 2 2 1 ZIP Zinc transporter TFIIA PF03153.8 GAP89625.1 - 0.0011 18.9 24.7 0.0023 17.9 17.1 1.6 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Peptidase_S8 PF00082.17 GAP89626.1 - 1.9e-45 155.1 10.9 1.9e-45 155.1 7.5 1.8 1 1 1 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.11 GAP89626.1 - 3e-13 50.1 2.5 5.3e-13 49.3 1.8 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 DAO PF01266.19 GAP89628.1 - 1.2e-14 53.9 0.3 4e-07 29.2 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 GAP89628.1 - 3.8e-11 42.6 0.2 0.00013 21.1 0.0 2.8 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 GAP89628.1 - 6e-08 32.5 0.5 1.6e-07 31.2 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAP89628.1 - 5e-05 23.2 0.4 0.0013 18.6 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP89628.1 - 0.00045 20.3 0.0 0.02 14.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAP89628.1 - 0.00048 19.0 2.8 0.0011 17.9 2.0 1.5 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 GAP89628.1 - 0.00057 19.0 1.1 0.056 12.5 0.2 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase GIDA PF01134.17 GAP89628.1 - 0.0015 17.4 1.0 0.0063 15.4 0.8 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 GAP89628.1 - 0.0061 15.2 1.9 0.047 12.3 0.3 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.22 GAP89628.1 - 0.0065 16.8 1.5 0.031 14.6 1.2 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAP89628.1 - 0.0067 14.9 1.9 0.036 12.5 0.7 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 GAP89628.1 - 0.016 14.3 1.6 0.029 13.4 1.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAP89628.1 - 0.016 14.9 0.5 0.12 12.1 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 GAP89628.1 - 0.028 14.0 0.1 0.064 12.9 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 GAP89628.1 - 0.056 13.0 0.3 0.17 11.4 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 GAP89628.1 - 0.071 12.1 0.3 0.13 11.3 0.2 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 GAP89628.1 - 0.091 11.6 0.4 1.9 7.3 0.2 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein PTR2 PF00854.16 GAP89630.1 - 6.7e-25 87.6 1.7 6.3e-24 84.4 1.2 2.1 1 1 0 1 1 1 1 POT family DUF3575 PF12099.3 GAP89630.1 - 0.019 14.0 0.1 0.031 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3575) Ribonuclease PF00545.15 GAP89631.1 - 1.1e-17 63.9 1.1 1.4e-17 63.5 0.4 1.4 1 1 0 1 1 1 1 ribonuclease COX4_pro_2 PF07835.7 GAP89631.1 - 2.1 8.3 4.7 0.25 11.3 0.4 1.6 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV GMC_oxred_N PF00732.14 GAP89632.1 - 1.1e-58 198.7 0.0 1.4e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAP89632.1 - 4e-32 111.4 0.0 6.8e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 GAP89632.1 - 0.00087 18.3 0.2 0.0014 17.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 GAP89632.1 - 0.00091 19.2 0.0 0.0027 17.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAP89632.1 - 0.051 12.6 0.1 0.094 11.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family PROCN PF08083.6 GAP89634.1 - 5e-221 733.3 7.4 9.6e-221 732.4 5.1 1.5 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 GAP89634.1 - 4.2e-124 412.3 1.1 7.8e-124 411.4 0.8 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 GAP89634.1 - 1.3e-93 310.6 0.9 2.7e-93 309.6 0.6 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 GAP89634.1 - 6.6e-76 253.1 3.5 1.1e-75 252.4 1.6 2.1 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 GAP89634.1 - 3.8e-67 224.0 0.1 8.5e-67 222.9 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 GAP89634.1 - 4.5e-44 148.2 0.1 1.3e-43 146.7 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 GAP89634.1 - 1.6e-40 137.6 0.0 4.2e-40 136.3 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain DUF3753 PF12575.3 GAP89634.1 - 0.095 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Ribosomal_L34e PF01199.13 GAP89635.1 - 3.1e-37 126.6 2.7 4e-37 126.3 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e DUF1428 PF07237.6 GAP89635.1 - 0.0098 15.7 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1428) FhuF_C PF11575.3 GAP89635.1 - 1.4 8.6 4.3 24 4.6 0.1 3.0 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain DUF498 PF04430.9 GAP89636.1 - 1.3e-26 92.2 0.0 1.7e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Abhydrolase_6 PF12697.2 GAP89637.1 - 1.7e-26 93.5 0.2 3e-26 92.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP89637.1 - 1.3e-14 54.1 0.0 3.4e-14 52.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP89637.1 - 2.5e-12 46.8 0.0 2.6e-11 43.5 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DSPc PF00782.15 GAP89637.1 - 2.8e-09 36.6 0.0 4e-08 32.9 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 GAP89637.1 - 6.1e-05 23.1 0.0 0.00014 21.8 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate PGAP1 PF07819.8 GAP89637.1 - 0.00042 19.9 0.4 0.0039 16.8 0.3 2.2 2 1 0 2 2 2 1 PGAP1-like protein Thioesterase PF00975.15 GAP89637.1 - 0.001 19.3 0.1 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain LCAT PF02450.10 GAP89637.1 - 0.0017 17.3 0.0 0.0028 16.7 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Y_phosphatase PF00102.22 GAP89637.1 - 0.0048 16.2 0.0 0.0078 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF2305 PF10230.4 GAP89637.1 - 0.0072 15.7 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Hydrolase_4 PF12146.3 GAP89637.1 - 0.016 15.0 0.0 0.042 13.7 0.0 1.8 1 1 0 1 1 1 0 Putative lysophospholipase FSH1 PF03959.8 GAP89637.1 - 0.036 13.5 0.0 0.33 10.3 0.0 2.1 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Ser_hydrolase PF06821.8 GAP89637.1 - 0.045 13.3 0.0 0.18 11.3 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase DUF900 PF05990.7 GAP89637.1 - 0.071 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Sad1_UNC PF07738.8 GAP89638.1 - 3.6e-33 114.2 0.0 5.7e-33 113.5 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal RRM_2 PF04059.7 GAP89639.1 - 2.5e-38 129.9 0.3 4.1e-38 129.2 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 Sec15 PF04091.7 GAP89641.1 - 1e-115 386.3 0.4 2.8e-115 384.9 0.3 1.8 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like DUF4201 PF13870.1 GAP89641.1 - 0.0013 18.1 3.8 0.0026 17.2 2.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) COG5 PF10392.4 GAP89641.1 - 0.052 13.5 5.6 2.8 7.8 1.7 3.7 3 0 0 3 3 3 0 Golgi transport complex subunit 5 Rnk_N PF14760.1 GAP89641.1 - 0.094 12.8 0.6 32 4.7 0.0 3.5 3 0 0 3 3 3 0 Rnk N-terminus COG2 PF06148.6 GAP89641.1 - 2.7 7.8 14.7 0.56 10.0 2.8 3.8 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 CBFD_NFYB_HMF PF00808.18 GAP89642.1 - 1.4e-19 69.8 0.6 2e-19 69.4 0.4 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAP89642.1 - 3e-11 43.2 0.1 4.3e-11 42.7 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 GAP89642.1 - 0.022 14.5 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Fcf2 PF08698.6 GAP89643.1 - 4.9e-30 103.4 0.1 1.2e-29 102.2 0.1 1.6 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing Pex14_N PF04695.8 GAP89643.1 - 0.026 14.5 1.1 0.026 14.5 0.7 1.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ADH_zinc_N_2 PF13602.1 GAP89644.1 - 4.6e-09 37.2 0.0 4.8e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 GAP89645.1 - 1.6e-09 37.4 0.6 3.2e-09 36.4 0.4 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP89645.1 - 1.4e-05 24.8 0.0 2.9e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 GAP89645.1 - 0.0031 17.0 0.3 0.0049 16.4 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Vps16_N PF04841.8 GAP89646.1 - 4.5e-95 318.6 0.0 7.6e-95 317.8 0.0 1.4 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 GAP89646.1 - 9.1e-77 258.1 0.0 1.3e-76 257.6 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region RRM_1 PF00076.17 GAP89647.1 - 2e-11 43.3 0.0 4.8e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP89647.1 - 4.2e-10 39.4 0.0 8.1e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP89647.1 - 1.6e-06 27.8 0.0 3.6e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Asp-B-Hydro_N PF05279.6 GAP89647.1 - 6.8 6.4 22.5 14 5.4 15.6 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region HrpB7 PF09486.5 GAP89648.1 - 0.11 12.4 0.1 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DivIC PF04977.10 GAP89648.1 - 3 7.3 10.1 4.1 6.9 1.0 2.7 2 1 0 2 2 2 0 Septum formation initiator MFS_1 PF07690.11 GAP89652.1 - 1.1e-24 86.8 72.8 6.4e-21 74.4 29.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cwf_Cwc_15 PF04889.7 GAP89653.1 - 1.7e-89 299.7 19.9 1.9e-89 299.5 13.8 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 GAP89653.1 - 0.15 9.9 26.2 0.19 9.6 18.2 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 GAP89653.1 - 0.18 11.0 24.1 0.22 10.7 16.7 1.2 1 0 0 1 1 1 0 SDA1 DUF506 PF04720.7 GAP89653.1 - 0.54 9.8 5.7 0.73 9.4 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF506) GEMIN8 PF15348.1 GAP89653.1 - 0.77 9.7 11.0 0.96 9.4 7.6 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 CDC45 PF02724.9 GAP89653.1 - 2.2 6.2 22.7 2.5 6.0 15.7 1.1 1 0 0 1 1 1 0 CDC45-like protein EMP24_GP25L PF01105.19 GAP89653.1 - 2.2 7.9 7.4 3.4 7.3 5.1 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD NOA36 PF06524.7 GAP89653.1 - 3.2 6.9 15.9 4.7 6.3 11.0 1.3 1 0 0 1 1 1 0 NOA36 protein NAM-associated PF14303.1 GAP89653.1 - 3.4 7.9 15.8 6.3 7.1 11.0 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Daxx PF03344.10 GAP89653.1 - 4.2 5.7 23.1 5.4 5.3 16.0 1.2 1 0 0 1 1 1 0 Daxx Family EBP PF05241.7 GAP89654.1 - 1e-58 197.5 7.2 1.2e-58 197.3 5.0 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF2781 PF10914.3 GAP89654.1 - 0.16 11.7 8.8 0.22 11.2 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) Zn_clus PF00172.13 GAP89655.1 - 1.4e-06 28.1 9.7 2.6e-06 27.2 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Homeobox_KN PF05920.6 GAP89657.1 - 2.6e-21 75.0 0.7 5.9e-21 73.8 0.5 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 GAP89657.1 - 3.6e-08 32.9 1.0 7.8e-08 31.8 0.7 1.6 1 0 0 1 1 1 1 Homeobox domain Fungal_trans PF04082.13 GAP89658.1 - 8.4e-12 44.5 0.9 1.8e-11 43.4 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP89658.1 - 3.9e-09 36.2 10.0 6.7e-09 35.5 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 GAP89658.1 - 4.3 7.5 9.2 2.4 8.3 4.5 1.9 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Rhodanese PF00581.15 GAP89659.1 - 3.2e-09 37.1 0.0 1e-08 35.4 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain Homeobox PF00046.24 GAP89659.1 - 6.8e-08 32.0 1.0 3.3e-07 29.8 0.0 2.4 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 GAP89659.1 - 0.043 13.5 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Homeobox KN domain FAD_binding_6 PF00970.19 GAP89661.1 - 5.4e-27 93.8 0.0 9.5e-27 93.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 GAP89661.1 - 9.1e-27 93.7 0.0 2e-26 92.6 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 GAP89661.1 - 0.00045 20.1 0.0 0.016 15.1 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 GAP89661.1 - 0.0086 16.0 0.0 0.066 13.1 0.0 2.1 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain DUF3605 PF12239.3 GAP89662.1 - 4e-53 179.4 0.1 5e-53 179.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) TPR_11 PF13414.1 GAP89663.1 - 2.4e-41 139.2 28.6 1.2e-12 47.2 0.9 7.8 5 3 2 7 7 7 7 TPR repeat TPR_1 PF00515.23 GAP89663.1 - 3.4e-39 130.8 20.7 5.9e-08 32.0 0.0 9.8 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 GAP89663.1 - 1.2e-36 121.6 33.3 3.1e-06 26.6 0.0 10.6 11 0 0 11 11 10 7 Tetratricopeptide repeat Apc3 PF12895.2 GAP89663.1 - 3e-29 100.9 27.9 1.2e-21 76.6 0.3 5.6 4 1 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 GAP89663.1 - 1.8e-26 91.8 28.6 3e-06 27.0 1.2 7.8 5 3 2 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 GAP89663.1 - 2.5e-26 89.4 14.6 7.6e-05 22.2 0.0 9.5 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 GAP89663.1 - 3e-22 78.7 33.9 1.2e-05 25.7 0.3 8.7 7 3 3 10 10 9 6 Tetratricopeptide repeat TPR_19 PF14559.1 GAP89663.1 - 8.4e-22 77.2 21.4 6.9e-08 32.7 3.5 6.8 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAP89663.1 - 2.7e-20 71.0 16.2 0.016 15.7 1.2 10.0 5 2 5 10 10 9 5 Tetratricopeptide repeat TPR_17 PF13431.1 GAP89663.1 - 4.2e-19 67.1 17.5 0.068 13.4 0.6 10.1 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAP89663.1 - 3.4e-13 48.2 16.4 0.02 14.6 0.0 8.5 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 GAP89663.1 - 9.8e-12 44.5 17.6 0.15 12.5 0.3 9.8 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAP89663.1 - 1.2e-05 25.1 14.6 0.014 15.1 0.9 5.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.9 GAP89663.1 - 0.0025 18.1 2.5 8.2 7.1 0.3 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2225 PF09986.4 GAP89663.1 - 0.0056 16.1 6.4 1.3 8.4 0.9 3.9 2 2 1 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) APP_E2 PF12925.2 GAP89663.1 - 0.072 12.6 6.0 4.7 6.7 0.2 4.4 3 1 3 6 6 5 0 E2 domain of amyloid precursor protein TPR_10 PF13374.1 GAP89663.1 - 0.079 12.9 12.5 2.1 8.4 0.3 5.9 6 1 1 7 7 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 GAP89663.1 - 0.11 12.3 10.0 0.5 10.2 0.2 5.6 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Sel1 PF08238.7 GAP89663.1 - 0.31 11.7 13.4 12 6.6 0.1 5.4 5 1 0 5 5 5 0 Sel1 repeat Histone PF00125.19 GAP89664.1 - 1.8e-15 56.7 0.1 2.2e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 GAP89664.1 - 0.00012 21.9 0.1 0.00017 21.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 GAP89664.1 - 0.00012 22.1 0.1 0.00017 21.7 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 GAP89664.1 - 0.00033 20.6 0.1 0.00059 19.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 GAP89664.1 - 0.013 15.2 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 GAP89664.1 - 0.022 14.0 0.0 0.022 14.0 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Sedlin_N PF04628.8 GAP89665.1 - 6.9e-40 135.9 0.0 8e-40 135.7 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 GAP89665.1 - 0.017 14.8 0.0 0.22 11.2 0.0 2.1 1 1 0 2 2 2 0 Sybindin-like family RRM_1 PF00076.17 GAP89666.1 - 8.5e-16 57.3 0.0 1.3e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP89666.1 - 2.5e-12 46.5 0.0 4e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP89666.1 - 8.8e-09 35.0 0.0 1.5e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup88 PF10168.4 GAP89667.1 - 0.00034 18.5 4.5 0.13 10.0 3.2 2.2 2 0 0 2 2 2 2 Nuclear pore component DMPK_coil PF08826.5 GAP89667.1 - 0.018 14.9 0.4 0.083 12.8 0.2 2.1 1 0 0 1 1 1 0 DMPK coiled coil domain like COP23 PF14218.1 GAP89667.1 - 0.046 13.2 0.2 0.087 12.3 0.1 1.4 1 0 0 1 1 1 0 Circadian oscillating protein COP23 Con-6 PF10346.4 GAP89667.1 - 0.05 13.0 0.0 0.098 12.0 0.0 1.5 1 0 0 1 1 1 0 Conidiation protein 6 Gp-FAR-1 PF05823.7 GAP89667.1 - 0.1 12.5 2.3 0.22 11.4 1.6 1.6 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) FliT PF05400.8 GAP89667.1 - 0.16 12.3 13.7 0.027 14.8 2.0 3.0 3 0 0 3 3 3 0 Flagellar protein FliT DUF4407 PF14362.1 GAP89667.1 - 0.24 10.3 7.2 0.4 9.6 5.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IncA PF04156.9 GAP89667.1 - 1.4 8.4 12.1 4.9 6.7 2.7 2.3 2 0 0 2 2 2 0 IncA protein PAT1 PF09770.4 GAP89668.1 - 0.44 8.7 10.8 0.53 8.4 7.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Bd3614_N PF14442.1 GAP89668.1 - 0.71 9.8 13.4 0.8 9.6 1.9 2.4 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal DUF4611 PF15387.1 GAP89668.1 - 1.8 8.7 11.6 5.1 7.3 1.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.5 GAP89668.1 - 3.4 7.9 11.0 6.4 7.0 1.7 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PI3_PI4_kinase PF00454.22 GAP89670.1 - 1.2e-29 103.4 0.0 2.2e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 GAP89670.1 - 8.6e-19 67.0 0.0 2.2e-18 65.7 0.0 1.8 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.15 GAP89670.1 - 0.17 11.0 0.6 0.38 9.9 0.4 1.5 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) CBFD_NFYB_HMF PF00808.18 GAP89671.1 - 8.5e-12 44.9 1.5 1.3e-11 44.3 1.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAP89671.1 - 2e-05 24.5 0.1 4e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 FGGY_N PF00370.16 GAP89672.1 - 1.3e-21 77.0 0.0 8.1e-13 48.2 0.0 2.4 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 GAP89672.1 - 2.5e-07 30.4 0.0 5.9e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Cation_efflux PF01545.16 GAP89673.1 - 3.1e-57 193.8 0.4 4e-57 193.4 0.3 1.1 1 0 0 1 1 1 1 Cation efflux family Med3 PF11593.3 GAP89673.1 - 0.0042 16.3 14.7 0.0081 15.4 10.2 1.4 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal SIR2 PF02146.12 GAP89674.1 - 5.1e-33 114.2 0.0 7.7e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Sir2 family OsmC PF02566.14 GAP89675.1 - 0.044 13.9 0.1 0.061 13.5 0.1 1.2 1 0 0 1 1 1 0 OsmC-like protein RAMP4 PF06624.7 GAP89675.1 - 0.07 12.6 0.2 1 8.9 0.0 2.2 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 Stm1_N PF09598.5 GAP89675.1 - 3.5 8.3 5.8 0.61 10.8 1.2 1.9 2 0 0 2 2 2 0 Stm1 APH PF01636.18 GAP89676.1 - 2.5e-16 60.1 0.0 8.2e-16 58.4 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAP89676.1 - 0.00038 20.1 0.0 0.015 14.8 0.0 2.3 2 0 0 2 2 2 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 GAP89676.1 - 0.0013 17.7 0.0 0.0022 17.0 0.0 1.3 1 0 0 1 1 1 1 Fructosamine kinase OpuAC PF04069.7 GAP89676.1 - 0.064 12.6 0.3 0.12 11.6 0.2 1.5 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system Peptidase_C50 PF03568.12 GAP89677.1 - 5.5e-105 351.1 0.0 1.1e-104 350.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.1 GAP89677.1 - 4.6e-07 29.6 23.6 0.011 15.6 1.0 7.6 6 3 3 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.1 GAP89677.1 - 1.2e-05 24.8 9.3 0.13 11.9 0.3 6.4 6 2 1 7 7 7 3 TPR repeat TPR_2 PF07719.12 GAP89677.1 - 0.00014 21.4 7.3 0.87 9.6 0.1 6.4 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 GAP89677.1 - 0.0045 17.0 10.0 0.071 13.2 0.0 5.0 5 0 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 GAP89677.1 - 0.12 12.0 7.3 1.6 8.4 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAP89677.1 - 0.15 11.9 3.7 6.7 6.7 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF2313 PF10076.4 GAP89677.1 - 0.38 10.1 6.2 0.078 12.3 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2313) PrpF PF04303.8 GAP89678.1 - 0.32 9.6 1.8 0.4 9.3 1.3 1.1 1 0 0 1 1 1 0 PrpF protein Fungal_trans PF04082.13 GAP89679.1 - 1.2e-25 89.8 0.0 1.8e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP89679.1 - 1.7e-09 37.4 10.9 2.8e-09 36.7 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kri1_C PF12936.2 GAP89680.1 - 1.1e-26 92.5 0.1 1.1e-26 92.5 0.1 4.0 3 1 1 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.7 GAP89680.1 - 1.2e-24 86.4 20.4 1.2e-24 86.4 14.1 5.0 5 1 0 5 5 5 1 KRI1-like family SSP160 PF06933.6 GAP89680.1 - 0.1 10.5 1.5 0.17 9.8 1.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ras PF00071.17 GAP89681.1 - 3.4e-58 195.6 0.0 4e-58 195.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAP89681.1 - 3.2e-20 72.8 0.0 5e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAP89681.1 - 7e-14 51.4 0.0 1.1e-13 50.7 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAP89681.1 - 7e-06 25.3 0.0 9.7e-06 24.8 0.0 1.2 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAP89681.1 - 8.3e-06 25.3 0.0 2.2e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAP89681.1 - 0.00021 21.2 0.0 0.00033 20.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 GAP89681.1 - 0.0077 16.2 0.0 0.014 15.4 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAP89681.1 - 0.057 13.5 0.0 0.19 11.9 0.0 1.8 2 1 0 2 2 2 0 AAA domain zf-RING_6 PF14835.1 GAP89682.1 - 0.00075 19.2 6.6 0.0011 18.6 4.6 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.1 GAP89682.1 - 0.0055 16.3 12.0 0.0088 15.6 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAP89682.1 - 1.2 9.1 13.5 2 8.4 9.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAP89682.1 - 1.4 8.6 12.9 2.3 8.0 8.9 1.3 1 0 0 1 1 1 0 zinc-RING finger domain ABM PF03992.11 GAP89683.1 - 4.2e-11 42.7 3.6 1.3e-05 25.1 2.0 2.3 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase PIG-X PF08320.7 GAP89684.1 - 3e-68 229.1 0.0 5.5e-68 228.3 0.0 1.4 1 0 0 1 1 1 1 PIG-X / PBN1 2OG-FeII_Oxy_3 PF13640.1 GAP89685.1 - 0.0042 17.5 0.0 0.012 16.0 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 GAP89685.1 - 0.0058 16.8 0.0 0.07 13.4 0.0 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Collagen PF01391.13 GAP89686.1 - 0.0035 16.8 4.3 0.01 15.3 3.0 1.8 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Mhr1 PF12829.2 GAP89687.1 - 2.3e-24 85.0 0.0 3.8e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination GoLoco PF02188.12 GAP89687.1 - 0.04 13.2 0.2 0.082 12.2 0.1 1.6 1 0 0 1 1 1 0 GoLoco motif K_channel_TID PF07941.6 GAP89687.1 - 0.31 11.3 3.0 2.3 8.4 0.2 2.5 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain AAA_2 PF07724.9 GAP89688.1 - 2.9e-47 160.7 0.0 1.8e-45 154.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 GAP89688.1 - 1.3e-27 96.6 0.0 1.4e-14 54.4 0.0 3.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 GAP89688.1 - 6.8e-24 83.5 1.4 2.8e-23 81.6 0.9 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 GAP89688.1 - 9.4e-17 61.5 15.5 3e-07 30.6 0.0 6.9 4 2 4 8 8 8 2 AAA ATPase domain AAA_5 PF07728.9 GAP89688.1 - 1.8e-16 60.1 0.1 2.7e-10 40.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 GAP89688.1 - 3.8e-13 49.7 0.1 0.00014 22.0 0.0 4.1 2 2 1 3 3 3 2 AAA domain Clp_N PF02861.15 GAP89688.1 - 8.5e-12 44.8 0.9 2e-06 27.6 0.0 4.0 3 0 0 3 3 3 2 Clp amino terminal domain Sigma54_activat PF00158.21 GAP89688.1 - 1.8e-09 37.3 0.0 5.9e-06 25.8 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.1 GAP89688.1 - 1.1e-08 35.9 1.7 0.01 16.6 0.0 4.0 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.1 GAP89688.1 - 7.5e-08 32.0 0.1 0.025 14.3 0.0 3.1 2 0 0 2 2 2 2 Part of AAA domain AAA_18 PF13238.1 GAP89688.1 - 2e-07 31.3 0.2 0.031 14.5 0.0 4.1 4 0 0 4 4 4 2 AAA domain IstB_IS21 PF01695.12 GAP89688.1 - 2.3e-06 27.1 0.0 0.072 12.5 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.1 GAP89688.1 - 9.7e-06 25.6 0.0 0.26 11.2 0.0 3.2 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 GAP89688.1 - 1.3e-05 24.5 0.2 0.28 10.3 0.0 3.5 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI T2SE PF00437.15 GAP89688.1 - 2.3e-05 23.4 0.1 0.0026 16.7 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein Arch_ATPase PF01637.13 GAP89688.1 - 5.4e-05 22.9 11.2 0.011 15.4 0.2 5.8 5 2 0 6 6 6 1 Archaeal ATPase AAA_3 PF07726.6 GAP89688.1 - 6.1e-05 22.6 0.0 0.66 9.5 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 GAP89688.1 - 9.9e-05 22.4 0.0 0.83 9.8 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.1 GAP89688.1 - 0.00028 20.7 0.1 1.5 8.6 0.0 3.4 3 0 0 3 3 2 2 AAA domain ResIII PF04851.10 GAP89688.1 - 0.00031 20.6 0.9 0.08 12.7 0.0 3.8 3 1 0 4 4 3 1 Type III restriction enzyme, res subunit AAA_29 PF13555.1 GAP89688.1 - 0.00044 19.7 0.0 0.82 9.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.1 GAP89688.1 - 0.0008 19.4 0.0 2.5 8.1 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain NTPase_1 PF03266.10 GAP89688.1 - 0.00096 18.8 0.0 0.27 10.9 0.0 3.6 3 0 0 3 3 3 1 NTPase AAA_24 PF13479.1 GAP89688.1 - 0.0013 18.3 0.0 0.91 9.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 GAP89688.1 - 0.0014 18.3 0.0 1.3 8.7 0.0 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 GAP89688.1 - 0.0014 18.9 0.2 1.7 8.9 0.0 3.1 3 0 0 3 3 2 1 ABC transporter AAA_10 PF12846.2 GAP89688.1 - 0.0017 17.8 4.2 0.19 11.1 0.0 4.4 5 1 0 5 5 5 1 AAA-like domain NACHT PF05729.7 GAP89688.1 - 0.002 17.8 0.0 0.37 10.4 0.0 2.9 2 0 0 2 2 2 1 NACHT domain Torsin PF06309.6 GAP89688.1 - 0.002 18.0 0.0 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 Torsin DUF258 PF03193.11 GAP89688.1 - 0.0033 16.6 0.0 0.47 9.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 GAP89688.1 - 0.0033 16.8 5.2 1.6 8.0 0.0 4.3 5 1 1 6 6 5 2 AAA domain UPF0079 PF02367.12 GAP89688.1 - 0.0097 15.5 0.0 5.6 6.6 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 GAP89688.1 - 0.081 12.8 0.9 2.1 8.2 0.0 3.6 3 2 0 3 3 3 0 50S ribosome-binding GTPase Peptidase_M16 PF00675.15 GAP89688.1 - 0.23 11.2 1.7 6 6.6 0.0 2.4 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) IncA PF04156.9 GAP89688.1 - 0.24 10.9 5.3 0.58 9.7 3.7 1.7 1 0 0 1 1 1 0 IncA protein Macoilin PF09726.4 GAP89688.1 - 0.95 7.6 13.2 0.34 9.1 7.4 1.4 2 0 0 2 2 2 0 Transmembrane protein HD PF01966.17 GAP89689.1 - 0.0016 18.4 0.1 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 HD domain PrpF PF04303.8 GAP89690.1 - 8.1e-57 192.6 0.5 4.8e-37 127.5 0.4 3.5 2 1 0 2 2 2 2 PrpF protein TPR_11 PF13414.1 GAP89691.1 - 1e-31 108.3 25.4 3.7e-07 29.6 0.1 10.4 9 2 1 10 10 10 6 TPR repeat TPR_2 PF07719.12 GAP89691.1 - 1.1e-26 90.5 16.1 0.0091 15.8 0.0 11.6 12 0 0 12 12 10 8 Tetratricopeptide repeat TPR_1 PF00515.23 GAP89691.1 - 6.3e-25 85.7 18.7 0.012 15.1 0.0 11.3 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_12 PF13424.1 GAP89691.1 - 4.7e-22 77.7 22.8 9.9e-08 31.8 0.0 9.2 7 3 1 8 8 7 5 Tetratricopeptide repeat TPR_7 PF13176.1 GAP89691.1 - 9.8e-22 74.9 12.6 0.00012 21.5 0.0 10.8 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_8 PF13181.1 GAP89691.1 - 2.2e-20 70.8 18.0 0.014 15.1 0.1 12.8 13 1 0 13 13 13 4 Tetratricopeptide repeat TPR_19 PF14559.1 GAP89691.1 - 1.7e-19 69.9 31.6 2.3e-06 27.8 0.3 11.4 11 1 1 12 12 12 6 Tetratricopeptide repeat TPR_14 PF13428.1 GAP89691.1 - 9.7e-19 66.1 21.1 0.00049 20.4 0.0 12.5 12 2 2 14 14 11 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAP89691.1 - 1.5e-17 63.7 25.6 0.0041 17.7 0.0 11.4 10 2 3 13 13 12 5 Tetratricopeptide repeat TPR_6 PF13174.1 GAP89691.1 - 5.5e-13 48.4 19.5 0.00015 21.9 0.0 10.8 12 0 0 12 12 11 3 Tetratricopeptide repeat Apc3 PF12895.2 GAP89691.1 - 5.2e-08 32.9 13.0 0.071 13.2 0.0 7.5 6 1 1 7 7 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 GAP89691.1 - 3.5e-07 29.8 16.4 1.9 8.8 0.1 11.6 13 0 0 13 13 12 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAP89691.1 - 9.1e-06 25.4 9.0 0.25 11.3 0.0 7.5 7 0 0 7 7 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 GAP89691.1 - 0.016 15.0 3.0 2.8 7.8 0.1 4.4 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.9 GAP89691.1 - 0.019 15.3 3.2 2.4 8.8 0.0 5.0 5 0 0 5 5 3 0 Tetratricopeptide repeat PPR PF01535.15 GAP89691.1 - 0.047 13.6 0.0 41 4.4 0.0 3.9 3 0 0 3 3 3 0 PPR repeat NUDIX PF00293.23 GAP89692.1 - 0.00044 19.9 0.0 0.00087 18.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Pkinase PF00069.20 GAP89693.1 - 5.5e-66 222.3 0.2 8.3e-66 221.7 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP89693.1 - 9.1e-47 159.2 0.2 1.5e-46 158.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 GAP89693.1 - 4.4e-23 81.4 0.1 2e-22 79.3 0.1 2.2 1 0 0 1 1 1 1 P21-Rho-binding domain PH_11 PF15413.1 GAP89693.1 - 1.1e-08 35.2 0.1 2.5e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.1 GAP89693.1 - 3.6e-08 32.7 0.0 5.8e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAP89693.1 - 0.0025 17.5 2.9 0.0042 16.8 0.1 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 GAP89693.1 - 0.022 13.6 0.0 0.037 12.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Brix PF04427.13 GAP89694.1 - 4.6e-32 111.2 0.1 9.6e-32 110.1 0.0 1.5 2 0 0 2 2 2 1 Brix domain Nop14 PF04147.7 GAP89694.1 - 0.49 8.2 18.6 0.65 7.8 12.9 1.1 1 0 0 1 1 1 0 Nop14-like family Nucleoside_tran PF01733.13 GAP89695.1 - 1.1e-41 143.0 8.3 9.8e-41 139.8 5.7 2.1 1 1 0 1 1 1 1 Nucleoside transporter Tom5 PF10642.4 GAP89695.1 - 0.057 13.0 0.2 0.17 11.5 0.1 1.8 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase Flu_M1_C PF08289.6 GAP89695.1 - 0.074 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain RseC_MucC PF04246.7 GAP89695.1 - 0.45 10.0 5.3 1.4 8.5 1.1 2.9 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Ins_P5_2-kin PF06090.7 GAP89696.1 - 6.9e-37 127.1 0.0 9e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase B3 PF02362.16 GAP89696.1 - 0.038 13.6 0.1 0.069 12.7 0.1 1.3 1 0 0 1 1 1 0 B3 DNA binding domain DUF2404 PF10296.4 GAP89697.1 - 6.1e-05 23.0 0.0 0.0002 21.3 0.0 1.9 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) YEATS PF03366.11 GAP89698.1 - 9.5e-24 82.9 0.7 1.5e-11 43.8 0.0 2.3 2 0 0 2 2 2 2 YEATS family PEP-utilisers_N PF05524.8 GAP89698.1 - 0.05 13.4 0.8 0.087 12.6 0.6 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal NAD_binding_10 PF13460.1 GAP89699.1 - 2.8e-14 53.5 0.0 4.8e-13 49.5 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAP89699.1 - 3.5e-07 29.9 0.0 2.5e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAP89699.1 - 3.7e-05 22.5 0.0 0.00022 20.0 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 GAP89699.1 - 0.00046 20.1 0.0 0.01 15.7 0.0 2.5 3 0 0 3 3 3 1 short chain dehydrogenase NAD_binding_4 PF07993.7 GAP89699.1 - 0.0023 16.8 0.0 0.18 10.7 0.0 2.5 2 2 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 GAP89699.1 - 0.029 13.2 0.0 0.2 10.4 0.0 2.3 3 0 0 3 3 3 0 RmlD substrate binding domain SYF2 PF08231.7 GAP89700.1 - 5.6e-50 169.4 11.1 5.6e-50 169.4 7.7 1.6 2 0 0 2 2 2 1 SYF2 splicing factor ARD PF03079.9 GAP89700.1 - 6.5 6.6 8.1 0.57 10.1 0.4 2.7 1 1 2 3 3 3 0 ARD/ARD' family Ecl1 PF12855.2 GAP89703.1 - 4.3e-12 45.1 2.9 7.3e-12 44.3 2.0 1.3 1 0 0 1 1 1 1 Life-span regulatory factor DUF581 PF04570.9 GAP89703.1 - 0.0036 16.5 1.0 0.0066 15.7 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF581) zf-MYND PF01753.13 GAP89703.1 - 0.028 14.3 1.3 0.049 13.5 0.9 1.3 1 0 0 1 1 1 0 MYND finger DUF2256 PF10013.4 GAP89703.1 - 4 7.2 6.6 36 4.2 4.6 2.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) DLH PF01738.13 GAP89704.1 - 4.9e-13 48.8 0.0 6.3e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 GAP89704.1 - 1.3e-06 28.1 0.0 1.8e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP89704.1 - 0.00063 19.3 0.0 0.00091 18.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAP89704.1 - 0.0019 18.1 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAP89704.1 - 0.008 15.4 0.2 0.025 13.8 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.15 GAP89704.1 - 0.017 14.5 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Putative esterase APH PF01636.18 GAP89705.1 - 5e-06 26.4 0.0 2.3e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF4135 PF13575.1 GAP89705.1 - 0.095 11.6 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) PCP_red PF08369.5 GAP89705.1 - 0.12 12.2 0.3 24 4.9 0.0 2.5 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit NPV_P10 PF05531.7 GAP89706.1 - 0.0025 18.0 0.5 0.0064 16.7 0.3 1.6 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein KCNQ_channel PF03520.9 GAP89706.1 - 0.0043 16.3 0.1 0.0084 15.4 0.1 1.4 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel IncA PF04156.9 GAP89706.1 - 0.0079 15.8 0.5 0.099 12.2 0.0 2.2 2 0 0 2 2 2 1 IncA protein CENP-F_leu_zip PF10473.4 GAP89706.1 - 0.013 15.3 0.6 0.076 12.8 0.2 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.4 GAP89706.1 - 0.019 15.1 2.7 0.12 12.4 0.3 3.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prefoldin_2 PF01920.15 GAP89706.1 - 0.043 13.5 3.4 0.25 11.0 0.3 2.7 2 1 0 2 2 2 0 Prefoldin subunit DUF1664 PF07889.7 GAP89706.1 - 0.046 13.5 0.6 0.21 11.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin PF00804.20 GAP89706.1 - 0.049 13.8 2.0 0.16 12.1 0.5 2.3 2 0 0 2 2 2 0 Syntaxin TBPIP PF07106.8 GAP89706.1 - 0.062 12.8 1.2 0.087 12.3 0.1 1.7 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DivIC PF04977.10 GAP89706.1 - 0.081 12.4 0.9 0.24 10.9 0.1 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF972 PF06156.8 GAP89706.1 - 0.12 12.7 1.2 0.32 11.3 0.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Allexi_40kDa PF05549.6 GAP89706.1 - 0.15 11.3 1.8 0.27 10.4 1.3 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein GAS PF13851.1 GAP89706.1 - 0.16 11.1 1.1 2.2 7.4 0.1 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3552 PF12072.3 GAP89706.1 - 0.18 10.9 1.3 0.34 10.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) LPP PF04728.8 GAP89706.1 - 0.19 11.5 2.5 0.44 10.3 1.2 2.0 2 0 0 2 2 1 0 Lipoprotein leucine-zipper V_ATPase_I PF01496.14 GAP89706.1 - 0.26 9.1 1.6 0.19 9.5 0.3 1.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family EzrA PF06160.7 GAP89706.1 - 0.4 8.7 2.0 0.33 9.0 0.1 1.6 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Uds1 PF15456.1 GAP89706.1 - 0.43 10.5 5.2 1.8 8.5 0.7 3.0 2 1 0 2 2 2 0 Up-regulated During Septation Reo_sigmaC PF04582.7 GAP89706.1 - 1 8.4 5.2 1.8 7.6 3.6 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Enkurin PF13864.1 GAP89706.1 - 1.1 9.5 4.4 7.7 6.7 0.1 3.0 3 0 0 3 3 3 0 Calmodulin-binding Fmp27_WPPW PF10359.4 GAP89706.1 - 1.7 6.9 6.3 0.35 9.2 2.0 1.4 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain TPR_MLP1_2 PF07926.7 GAP89706.1 - 6.4 6.5 7.6 1.9 8.2 0.2 2.8 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Plasmodium_Vir PF05795.6 GAP89707.1 - 0.91 8.6 6.3 0.1 11.7 0.7 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein TIP41 PF04176.8 GAP89708.1 - 5e-66 221.4 0.2 2.4e-39 134.4 0.3 2.1 2 0 0 2 2 2 2 TIP41-like family Glyco_hydro_18 PF00704.23 GAP89709.1 - 1e-15 58.0 1.1 1.7e-14 54.0 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 DUF1212 PF06738.7 GAP89710.1 - 6.7e-52 175.7 19.3 2.5e-50 170.6 0.9 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 GAP89710.1 - 1.5e-22 79.9 16.5 1.5e-22 79.9 11.4 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) CH PF00307.26 GAP89711.1 - 1.2e-08 34.9 0.0 1.8e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain NDUFA12 PF05071.11 GAP89712.1 - 3.2e-14 53.2 1.5 5.5e-14 52.5 0.2 2.0 1 1 1 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PAT1 PF09770.4 GAP89712.1 - 9.6 4.3 16.4 11 4.1 11.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sod_Fe_C PF02777.13 GAP89715.1 - 1.4e-35 121.2 0.2 2.2e-35 120.6 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 GAP89715.1 - 2.3e-33 114.3 3.3 3.4e-33 113.7 0.3 2.1 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Zn_clus PF00172.13 GAP89716.1 - 9.3e-10 38.2 5.2 1.9e-09 37.2 3.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAP89716.1 - 0.0038 16.1 0.0 0.007 15.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_C2 PF00648.16 GAP89718.1 - 5.5e-52 176.6 2.1 6.6e-36 123.8 0.5 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease NicO PF03824.11 GAP89719.1 - 3.1e-64 217.0 9.0 5.2e-64 216.2 6.2 1.4 1 0 0 1 1 1 1 High-affinity nickel-transport protein ADH_zinc_N PF00107.21 GAP89720.1 - 2.2e-07 30.5 0.2 4e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP89720.1 - 2.9e-05 23.7 0.0 4.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Tyrosinase PF00264.15 GAP89721.1 - 9.6e-45 153.4 1.1 1.3e-44 153.0 0.8 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Amidase PF01425.16 GAP89722.1 - 2.6e-90 303.4 0.1 1.6e-88 297.4 0.0 2.0 1 1 0 1 1 1 1 Amidase MFS_1 PF07690.11 GAP89723.1 - 1.9e-29 102.5 28.9 1.9e-29 102.5 20.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 GAP89724.1 - 1.8e-20 72.9 0.3 3.5e-20 71.9 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP89724.1 - 2e-07 30.7 10.8 4.4e-07 29.6 7.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RdRP PF05183.7 GAP89725.1 - 3.1e-122 409.2 0.5 4.3e-122 408.7 0.4 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF1324 PF07038.6 GAP89726.1 - 0.079 12.9 0.5 0.15 12.0 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1324) Legionella_OMP PF05150.7 GAP89726.1 - 0.085 11.9 0.1 0.097 11.7 0.1 1.0 1 0 0 1 1 1 0 Legionella pneumophila major outer membrane protein precursor Peptidase_M35 PF02102.10 GAP89726.1 - 0.3 9.6 2.5 0.33 9.5 1.8 1.2 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family Glyco_hydro_20 PF00728.17 GAP89727.1 - 3.9e-37 128.2 0.5 2.4e-36 125.6 0.3 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.10 GAP89727.1 - 6.1e-06 26.7 0.0 1.1e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 RIO1 PF01163.17 GAP89728.1 - 5.8e-68 227.9 0.0 5.8e-68 227.9 0.0 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 GAP89728.1 - 0.00077 19.2 0.3 0.024 14.3 0.2 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 GAP89728.1 - 0.0012 17.9 0.2 0.8 8.7 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M14 PF00246.19 GAP89729.1 - 9.2e-68 228.8 0.0 1.1e-67 228.5 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Prothymosin PF03247.9 GAP89730.1 - 0.46 10.6 27.2 0.091 12.9 8.3 2.3 2 0 0 2 2 2 0 Prothymosin/parathymosin family SDA1 PF05285.7 GAP89730.1 - 0.98 8.6 17.4 1.4 8.1 12.0 1.2 1 0 0 1 1 1 0 SDA1 DUF2271 PF10029.4 GAP89731.1 - 0.24 10.9 1.8 3 7.3 0.2 2.4 1 1 1 2 2 2 0 Predicted periplasmic protein (DUF2271) RE_ScaI PF09569.5 GAP89733.1 - 0.0098 15.3 0.6 0.014 14.9 0.4 1.2 1 0 0 1 1 1 1 ScaI restriction endonuclease APH PF01636.18 GAP89733.1 - 0.051 13.2 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family SSPI PF14098.1 GAP89733.1 - 0.068 13.0 0.1 0.18 11.7 0.1 1.7 1 0 0 1 1 1 0 Small, acid-soluble spore protein I PP2C PF00481.16 GAP89734.1 - 7.4e-60 202.4 0.1 6.5e-50 169.8 0.1 3.2 2 1 0 3 3 3 2 Protein phosphatase 2C Snf7 PF03357.16 GAP89735.1 - 2.7e-35 121.2 22.2 4.6e-35 120.5 13.6 1.9 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.9 GAP89735.1 - 0.013 14.9 6.9 0.023 14.0 4.8 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway DFF40 PF09230.5 GAP89735.1 - 0.55 9.5 6.4 0.45 9.8 3.7 1.3 1 1 0 1 1 1 0 DNA fragmentation factor 40 kDa Hpt PF01627.18 GAP89735.1 - 2.5 8.1 6.0 2.2 8.3 1.1 2.6 1 1 1 2 2 2 0 Hpt domain Dynamin_N PF00350.18 GAP89736.1 - 5.8e-17 62.0 0.6 2.1e-16 60.1 0.0 2.2 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 GAP89736.1 - 1.9e-09 37.4 0.0 9.4e-09 35.2 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAP89736.1 - 3.5e-07 29.8 1.4 5.6e-06 25.9 1.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MitMem_reg PF13012.1 GAP89736.1 - 0.0077 16.3 1.0 3.6 7.7 0.1 2.8 2 0 0 2 2 2 2 Maintenance of mitochondrial structure and function AAA_29 PF13555.1 GAP89736.1 - 0.03 13.8 0.1 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Miro PF08477.8 GAP89736.1 - 0.035 14.5 0.1 0.52 10.8 0.1 2.6 1 1 0 1 1 1 0 Miro-like protein FH2 PF02181.18 GAP89736.1 - 0.035 12.9 0.9 0.078 11.8 0.6 1.5 1 0 0 1 1 1 0 Formin Homology 2 Domain PMEI PF04043.10 GAP89736.1 - 0.045 13.6 0.2 0.14 12.0 0.1 1.8 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Glycoprotein_B PF00606.13 GAP89737.1 - 0.033 12.2 4.3 0.036 12.1 3.0 1.0 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B Rab5ip PF07019.7 GAP89737.1 - 0.21 11.7 9.7 0.08 13.0 4.4 1.9 1 1 1 2 2 2 0 Rab5-interacting protein (Rab5ip) Halogen_Hydrol PF10112.4 GAP89737.1 - 0.6 9.4 2.3 0.71 9.2 1.6 1.2 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Elf1 PF05129.8 GAP89739.1 - 8.3 6.1 9.5 1.4 8.6 0.6 2.8 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like EHN PF06441.7 GAP89741.1 - 7e-34 116.1 0.4 4.3e-33 113.5 0.0 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 GAP89741.1 - 2.1e-10 40.8 1.7 3.2e-09 36.9 2.2 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP89741.1 - 1.7e-08 34.3 0.0 9.2e-07 28.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold ADH_zinc_N PF00107.21 GAP89742.1 - 4.6e-06 26.2 0.5 8.2e-06 25.3 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP89742.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain bZIP_1 PF00170.16 GAP89743.1 - 9e-06 25.5 7.5 1.8e-05 24.5 5.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor RED_N PF07808.8 GAP89743.1 - 0.054 12.7 9.3 0.089 12.0 0.5 2.1 2 0 0 2 2 2 0 RED-like protein N-terminal region DUF4407 PF14362.1 GAP89743.1 - 6.3 5.6 11.6 2.7 6.8 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HABP4_PAI-RBP1 PF04774.10 GAP89744.1 - 0.0008 19.8 4.7 0.0008 19.8 3.3 2.3 2 0 0 2 2 2 1 Hyaluronan / mRNA binding family API5 PF05918.6 GAP89744.1 - 0.039 12.4 7.2 0.048 12.1 5.0 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF605 PF04652.11 GAP89745.1 - 1.2 8.4 9.7 1.6 8.0 6.7 1.1 1 0 0 1 1 1 0 Vta1 like Zn_clus PF00172.13 GAP89746.1 - 5.6e-08 32.5 10.8 5.6e-08 32.5 7.5 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 GAP89747.1 - 1e-46 159.3 34.7 1.2e-46 159.1 24.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP89747.1 - 5.1e-15 54.9 9.1 5.1e-15 54.9 6.3 2.6 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 GAP89747.1 - 7.9e-05 21.0 4.1 0.00012 20.4 2.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 GAP89747.1 - 0.00018 20.0 14.6 0.0078 14.6 1.7 3.3 1 1 0 2 2 2 2 MFS/sugar transport protein OATP PF03137.15 GAP89747.1 - 0.0034 15.5 7.8 0.018 13.1 0.6 2.5 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 GAP89747.1 - 0.0069 14.5 2.2 0.011 13.9 1.5 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector DUF2583 PF10762.4 GAP89747.1 - 0.9 9.7 5.1 0.38 10.9 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) p450 PF00067.17 GAP89748.1 - 1.1e-37 129.7 0.1 1.4e-37 129.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 GAP89749.1 - 3.4e-26 91.3 1.4 1.5e-25 89.2 0.4 2.4 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 GAP89749.1 - 0.00041 20.2 0.1 0.0023 17.7 0.0 2.1 2 0 0 2 2 2 1 Berberine and berberine like p450 PF00067.17 GAP89751.1 - 1e-48 166.0 0.0 1.3e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AAA_14 PF13173.1 GAP89751.1 - 0.014 15.2 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Flagellin_C PF00700.16 GAP89751.1 - 0.11 12.6 0.4 0.93 9.6 0.4 2.0 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region polyprenyl_synt PF00348.12 GAP89752.1 - 6.1e-28 97.3 0.0 1.4e-27 96.2 0.0 1.5 1 1 0 1 1 1 1 Polyprenyl synthetase UTP15_C PF09384.5 GAP89752.1 - 0.037 13.7 0.3 0.12 12.0 0.1 1.9 1 1 1 2 2 2 0 UTP15 C terminal p450 PF00067.17 GAP89753.1 - 2.6e-41 141.6 0.0 3.4e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aldo_ket_red PF00248.16 GAP89754.1 - 2.5e-45 154.5 0.0 2.8e-45 154.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Prenyltrans_1 PF13243.1 GAP89755.1 - 1.3e-07 31.5 0.5 0.0083 16.1 0.0 3.3 3 0 0 3 3 3 2 Prenyltransferase-like Prenyltrans_2 PF13249.1 GAP89755.1 - 7.4e-05 23.1 4.9 0.2 12.0 0.0 4.7 3 1 2 5 5 5 3 Prenyltransferase-like Terpene_synth_C PF03936.11 GAP89755.1 - 0.0011 18.2 0.1 0.012 14.8 0.0 2.2 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain G2F PF07474.7 GAP89756.1 - 0.09 12.1 0.1 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 G2F domain zf-C2H2 PF00096.21 GAP89757.1 - 9.1e-29 98.0 58.7 3.6e-05 23.8 0.2 10.4 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP89757.1 - 1.3e-24 84.6 60.4 0.00012 22.1 0.4 10.1 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAP89757.1 - 5.4e-12 45.3 68.6 0.00015 21.8 0.1 11.1 12 1 0 12 12 12 6 Zinc-finger double domain zf-met PF12874.2 GAP89757.1 - 5.7e-05 23.1 25.4 0.69 10.2 0.1 8.2 10 0 0 10 10 10 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 GAP89757.1 - 8.1e-05 22.6 35.3 0.057 13.5 0.3 8.6 9 0 0 9 9 9 4 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 GAP89757.1 - 3.5 8.0 0.0 3.5 8.0 0.0 9.3 10 1 0 10 10 10 0 C2H2-type zinc-finger domain RNA_pol_Rpb6 PF01192.17 GAP89758.1 - 1.6e-24 85.4 0.3 1.6e-24 85.4 0.2 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb6 Toxin_2 PF00451.14 GAP89759.1 - 0.28 11.3 3.2 5.2 7.2 0.6 2.6 2 0 0 2 2 2 0 Scorpion short toxin, BmKK2 DUF3586 PF12131.3 GAP89759.1 - 2.3 8.2 5.6 0.21 11.6 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3586) Esterase PF00756.15 GAP89760.1 - 1.6e-47 162.1 0.0 2.1e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 GAP89760.1 - 1.1e-06 28.4 0.1 1.8e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP89760.1 - 7.6e-06 25.9 1.7 1.4e-05 25.0 1.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAP89760.1 - 4.5e-05 22.7 0.3 0.00016 20.9 0.0 2.0 2 1 0 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 GAP89760.1 - 0.0034 16.6 0.1 0.72 9.0 0.0 2.2 2 0 0 2 2 2 2 Esterase PHB depolymerase Abhydrolase_1 PF00561.15 GAP89760.1 - 0.037 13.5 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 GAP89760.1 - 0.14 11.0 0.0 0.42 9.4 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase enzyme Afi1 PF07792.7 GAP89761.1 - 4.4e-63 211.6 0.1 8.6e-63 210.6 0.0 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 GAP89761.1 - 4.4e-35 119.8 0.0 8.4e-35 118.8 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 GAP89761.1 - 3.3e-07 29.1 0.1 0.029 12.8 0.0 3.6 3 1 1 4 4 4 2 Transport protein Avl9 DUF2347 PF09804.4 GAP89761.1 - 0.076 12.2 0.0 0.34 10.1 0.0 2.1 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) Nop14 PF04147.7 GAP89761.1 - 0.13 10.1 10.1 0.2 9.5 7.0 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.8 GAP89761.1 - 0.4 10.5 11.7 0.75 9.6 8.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.7 GAP89761.1 - 0.47 10.1 15.2 0.99 9.0 10.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein AMP-binding PF00501.23 GAP89762.1 - 2.2e-84 283.2 0.0 3.9e-84 282.4 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 GAP89762.1 - 2.1e-76 256.7 0.0 4.6e-76 255.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 GAP89762.1 - 2.1e-57 193.7 0.1 2.7e-50 170.5 0.0 2.7 2 0 0 2 2 2 2 KR domain adh_short PF00106.20 GAP89762.1 - 1.1e-50 171.8 0.2 2e-41 141.7 0.0 3.1 2 0 0 2 2 2 2 short chain dehydrogenase PS-DH PF14765.1 GAP89762.1 - 6e-46 156.9 0.0 1.3e-45 155.8 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 GAP89762.1 - 8.3e-46 156.7 0.1 1.6e-45 155.8 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain Condensation PF00668.15 GAP89762.1 - 6.5e-40 136.8 0.2 1.3e-39 135.8 0.1 1.5 1 0 0 1 1 1 1 Condensation domain NAD_binding_4 PF07993.7 GAP89762.1 - 1.6e-29 102.5 0.0 2.8e-27 95.2 0.0 2.8 2 1 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.17 GAP89762.1 - 2.4e-29 101.6 0.0 7.6e-29 99.9 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 GAP89762.1 - 2.4e-20 72.8 0.0 3.7e-19 69.0 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 GAP89762.1 - 1.7e-16 60.2 3.1 2.1e-07 31.1 0.0 3.2 3 0 0 3 3 3 2 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 GAP89762.1 - 1.1e-12 48.0 0.0 3.2e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP89762.1 - 5e-12 46.1 0.0 2.6e-11 43.8 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 GAP89762.1 - 2.3e-09 37.4 0.1 7e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_31 PF13847.1 GAP89762.1 - 7e-09 35.4 0.0 2.6e-08 33.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP89762.1 - 1.9e-08 34.8 0.0 3.1e-07 30.9 0.0 3.1 4 0 0 4 4 1 1 Methyltransferase domain Epimerase PF01370.16 GAP89762.1 - 5.2e-08 32.6 0.0 3.7e-06 26.5 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Ubie_methyltran PF01209.13 GAP89762.1 - 2.7e-07 29.9 0.0 6.6e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family AMP-binding_C PF13193.1 GAP89762.1 - 5.2e-07 30.5 0.1 2.3e-06 28.4 0.1 2.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.18 GAP89762.1 - 4.2e-06 25.9 0.0 8.1e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain RrnaAD PF00398.15 GAP89762.1 - 0.0068 15.4 0.1 0.029 13.4 0.0 2.1 3 0 0 3 3 2 1 Ribosomal RNA adenine dimethylase DUF938 PF06080.7 GAP89762.1 - 0.011 15.2 0.1 0.063 12.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Methyltransf_16 PF10294.4 GAP89762.1 - 0.018 14.5 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Saccharop_dh PF03435.13 GAP89762.1 - 0.032 13.2 0.0 2.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 GAP89762.1 - 0.032 12.9 0.0 2.8 6.5 0.0 2.4 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Acetyltransf_1 PF00583.19 GAP89762.1 - 0.035 14.1 0.0 11 6.1 0.0 3.7 3 0 0 3 3 3 0 Acetyltransferase (GNAT) family Semialdhyde_dh PF01118.19 GAP89762.1 - 0.038 14.2 0.0 0.35 11.1 0.0 2.5 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 GAP89762.1 - 0.097 11.5 0.0 0.73 8.6 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF466 PF04328.8 GAP89762.1 - 0.29 10.9 0.2 1.1 9.0 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF466) Fungal_trans PF04082.13 GAP89763.1 - 4.1e-15 55.3 0.0 5.7e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 GAP89764.1 - 9.5e-46 156.1 39.9 9.5e-46 156.1 27.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP89764.1 - 5.2e-07 28.6 36.4 1.8e-06 26.8 24.8 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 GAP89764.1 - 0.00019 19.9 26.2 0.0045 15.4 6.9 3.1 1 1 1 2 2 2 2 MFS/sugar transport protein Zn_clus PF00172.13 GAP89765.1 - 6.8e-05 22.6 12.3 0.00014 21.7 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.2 GAP89766.1 - 1.3e-13 51.0 0.0 0.0035 17.6 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAP89766.1 - 1.1e-06 28.2 0.1 1.8 9.0 0.0 5.6 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.25 GAP89766.1 - 5.2e-06 26.0 3.1 0.042 13.6 0.0 5.0 8 0 0 8 8 8 2 Ankyrin repeat Ank_4 PF13637.1 GAP89766.1 - 3.3e-05 24.2 1.2 0.7 10.4 0.0 4.9 3 2 1 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP89766.1 - 0.0056 16.8 0.1 1.5 9.1 0.0 4.0 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Pox_F15 PF04596.7 GAP89766.1 - 0.11 12.1 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 Poxvirus protein F15 Dioxygenase_C PF00775.16 GAP89768.1 - 1.2e-10 40.8 1.7 7.3e-10 38.4 1.2 2.1 1 1 0 1 1 1 1 Dioxygenase zf-C2H2_4 PF13894.1 GAP89769.1 - 0.00052 20.1 4.4 0.00052 20.1 3.1 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 GAP89769.1 - 0.002 18.3 5.1 0.0048 17.1 3.6 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type DUF1777 PF08648.7 GAP89769.1 - 7.3 6.2 28.3 0.13 12.0 13.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) PNP_UDP_1 PF01048.15 GAP89770.1 - 6.7e-13 48.1 0.1 2.4e-12 46.3 0.0 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily AAA PF00004.24 GAP89771.1 - 2e-17 63.6 0.0 6e-17 62.0 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 GAP89771.1 - 0.0012 18.5 0.1 0.003 17.2 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 GAP89771.1 - 0.0055 16.7 1.3 0.014 15.3 0.2 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAP89771.1 - 0.006 16.7 1.8 0.051 13.7 0.1 2.9 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.9 GAP89771.1 - 0.015 15.0 0.1 0.046 13.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 GAP89771.1 - 0.054 14.3 0.1 0.86 10.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 GAP89771.1 - 0.057 12.9 0.2 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 GAP89771.1 - 0.11 12.4 0.0 0.84 9.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 GAP89771.1 - 0.12 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.1 GAP89771.1 - 0.17 11.4 0.2 0.83 9.1 0.0 2.1 1 1 1 2 2 2 0 AAA domain Mtc PF03820.12 GAP89772.1 - 4.8e-102 340.7 0.3 3.7e-101 337.8 0.2 1.9 1 1 0 1 1 1 1 Tricarboxylate carrier Pkinase PF00069.20 GAP89773.1 - 2.9e-58 197.0 0.0 5.1e-58 196.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP89773.1 - 7.6e-20 71.0 0.0 2.5e-19 69.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Trypan_PARP PF05887.6 GAP89773.1 - 0.05 13.4 6.8 0.14 11.9 4.7 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pox_ser-thr_kin PF05445.6 GAP89773.1 - 0.094 11.4 0.1 0.14 10.8 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Lactamase_B_2 PF12706.2 GAP89776.1 - 1.2e-30 106.5 0.2 1.8e-30 105.9 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 GAP89776.1 - 1.1e-06 28.5 0.2 3e-06 27.0 0.1 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF2188 PF09954.4 GAP89776.1 - 0.021 14.7 0.1 0.066 13.1 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) W2 PF02020.13 GAP89776.1 - 0.15 12.0 0.1 0.34 10.8 0.1 1.5 1 0 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon Lactamase_B_4 PF13691.1 GAP89777.1 - 1.1e-26 92.1 0.0 3e-26 90.6 0.0 1.8 2 0 0 2 2 2 1 tRNase Z endonuclease Glyco_hydro_16 PF00722.16 GAP89778.1 - 6.3e-11 41.8 0.5 1.1e-10 41.0 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Zn_clus PF00172.13 GAP89779.1 - 1.1e-08 34.8 9.6 1.6e-08 34.3 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pex14_N PF04695.8 GAP89779.1 - 0.74 9.8 5.1 0.37 10.8 1.5 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HET PF06985.6 GAP89780.1 - 3.5e-06 27.2 0.1 6.3e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Spt5_N PF11942.3 GAP89780.1 - 1.4 9.6 9.9 3.1 8.4 6.9 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Ank_2 PF12796.2 GAP89781.1 - 3.6e-139 453.5 37.4 3.8e-18 65.6 0.4 15.7 2 2 13 17 17 17 17 Ankyrin repeats (3 copies) Ank PF00023.25 GAP89781.1 - 2.5e-99 320.5 54.9 1e-07 31.3 0.2 30.0 31 0 0 31 31 31 22 Ankyrin repeat Ank_4 PF13637.1 GAP89781.1 - 4.5e-93 304.1 38.8 1.6e-08 34.8 0.0 23.0 9 4 14 25 25 25 22 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP89781.1 - 3.4e-87 284.5 37.3 3.1e-09 36.7 0.1 22.6 10 4 14 25 25 25 19 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP89781.1 - 4.6e-81 258.5 26.5 3.5e-06 26.7 0.0 29.3 30 0 0 30 30 30 16 Ankyrin repeat SPRY PF00622.23 GAP89781.1 - 5.6e-18 65.2 0.3 1.4e-17 63.9 0.2 1.6 1 0 0 1 1 1 1 SPRY domain adh_short PF00106.20 GAP89781.1 - 7.2e-16 58.5 0.1 2.2e-15 56.9 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP89781.1 - 2.4e-06 27.3 0.9 6.4e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 KR domain Shigella_OspC PF06128.6 GAP89781.1 - 0.024 14.1 0.0 2.6 7.4 0.0 3.8 5 0 0 5 5 5 0 Shigella flexneri OspC protein DUF3447 PF11929.3 GAP89781.1 - 0.077 12.8 0.0 23 4.8 0.0 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF3447) Pkinase PF00069.20 GAP89782.1 - 4e-08 32.7 0.0 6.3e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 GAP89782.1 - 0.046 13.4 0.0 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 GAP89782.1 - 0.099 11.6 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-H2C2_2 PF13465.1 GAP89784.1 - 2.5 8.5 5.6 43 4.6 0.0 3.7 3 0 0 3 3 3 0 Zinc-finger double domain Flavin_Reduct PF01613.13 GAP89786.1 - 1.9e-17 63.5 1.1 7.3e-17 61.6 0.0 2.0 2 0 0 2 2 2 1 Flavin reductase like domain Ribosomal_60s PF00428.14 GAP89786.1 - 0.0091 16.3 1.3 0.03 14.6 0.9 1.9 1 0 0 1 1 1 1 60s Acidic ribosomal protein Serglycin PF04360.7 GAP89786.1 - 0.049 13.3 0.1 0.073 12.7 0.1 1.2 1 0 0 1 1 1 0 Serglycin HET PF06985.6 GAP89787.1 - 4.1e-28 98.2 0.0 6e-26 91.2 0.0 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HAUS4 PF14735.1 GAP89787.1 - 0.094 12.0 0.1 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 PDEase_II PF02112.10 GAP89788.1 - 1.7e-54 185.0 0.0 6.9e-47 159.9 0.0 2.9 2 1 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 GAP89788.1 - 5.5e-05 22.8 0.0 0.00028 20.4 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 GAP89788.1 - 0.099 12.2 2.8 0.36 10.4 2.0 2.0 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Aldose_epim PF01263.15 GAP89789.1 - 0.13 11.3 0.0 0.51 9.3 0.0 1.8 1 1 1 2 2 2 0 Aldose 1-epimerase AMP-binding PF00501.23 GAP89790.1 - 1e-61 208.6 0.5 4.9e-23 81.2 0.0 4.8 4 1 0 4 4 4 4 AMP-binding enzyme DMAP_binding PF06464.6 GAP89790.1 - 3.5e-10 40.4 0.2 1e-09 38.9 0.2 1.8 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.7 GAP89790.1 - 0.00077 19.2 2.9 0.0016 18.1 2.0 1.5 1 0 0 1 1 1 1 Gas vesicle protein G Metallophos PF00149.23 GAP89791.1 - 2.2e-20 72.8 0.0 7e-20 71.2 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 GAP89791.1 - 2.1e-11 43.7 0.0 4e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 GAP89791.1 - 8.8e-10 37.7 0.0 2.1e-07 29.8 0.0 2.1 2 0 0 2 2 2 2 PhoD-like phosphatase Metallophos_2 PF12850.2 GAP89791.1 - 0.0008 19.2 0.0 0.0025 17.6 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Arf PF00025.16 GAP89792.1 - 1e-73 246.2 0.0 1.1e-73 246.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 GAP89792.1 - 5.9e-13 48.4 0.0 7.3e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 GAP89792.1 - 1.5e-11 43.6 0.7 9e-08 31.1 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 GAP89792.1 - 1.5e-11 43.9 0.0 1.7e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAP89792.1 - 1.6e-08 35.0 0.0 2.2e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 GAP89792.1 - 2.6e-08 33.2 0.0 3.1e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAP89792.1 - 6.2e-06 26.1 0.0 8.9e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAP89792.1 - 1.5e-05 24.4 0.1 0.0018 17.7 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 GAP89792.1 - 0.0052 15.5 0.4 0.02 13.6 0.1 2.0 2 1 0 2 2 2 1 ArgK protein FeoB_N PF02421.13 GAP89792.1 - 0.0081 15.4 0.6 0.039 13.2 0.4 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF3986 PF13143.1 GAP89792.1 - 0.099 13.1 0.2 0.27 11.7 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) Skp1 PF01466.14 GAP89793.1 - 2.6e-39 133.1 1.1 2.6e-39 133.1 0.8 1.9 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 GAP89793.1 - 6.4e-22 77.4 0.3 1.3e-21 76.4 0.1 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 GAP89793.1 - 0.018 15.0 0.4 0.041 13.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) BTB PF00651.26 GAP89793.1 - 0.057 13.4 0.0 0.26 11.3 0.0 2.0 1 1 0 1 1 1 0 BTB/POZ domain DUF4203 PF13886.1 GAP89794.1 - 6.3e-35 120.5 23.2 8.3e-35 120.1 16.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF4381 PF14316.1 GAP89794.1 - 0.39 10.8 4.6 1 9.4 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) IncA PF04156.9 GAP89795.1 - 0.014 14.9 1.7 0.031 13.8 1.2 1.5 1 0 0 1 1 1 0 IncA protein MitMem_reg PF13012.1 GAP89795.1 - 0.07 13.2 0.2 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function CCDC-167 PF15188.1 GAP89795.1 - 0.089 12.7 1.2 0.36 10.8 0.1 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Erf4 PF10256.4 GAP89796.1 - 1.5e-29 102.2 0.0 2.2e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family STE3 PF02076.10 GAP89798.1 - 6.6e-48 163.2 13.0 8.2e-48 162.9 9.0 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF4281 PF14108.1 GAP89798.1 - 0.087 12.9 2.5 0.3 11.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4281) Serglycin PF04360.7 GAP89798.1 - 0.5 10.0 3.7 0.96 9.1 2.6 1.4 1 0 0 1 1 1 0 Serglycin MFS_1 PF07690.11 GAP89799.1 - 6.1e-18 64.6 19.5 6.1e-18 64.6 13.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily RINGv PF12906.2 GAP89800.1 - 1.5e-16 60.1 9.1 2.4e-16 59.4 6.3 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 GAP89800.1 - 0.023 14.5 8.5 0.039 13.7 5.9 1.4 1 0 0 1 1 1 0 Ring finger domain zf-Apc11 PF12861.2 GAP89800.1 - 0.13 12.1 2.7 0.28 11.0 1.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 GAP89800.1 - 0.19 11.8 3.2 0.44 10.6 2.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_4 PF14570.1 GAP89800.1 - 0.93 9.1 6.7 1.6 8.3 4.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain MT0933_antitox PF14013.1 GAP89801.1 - 5 7.3 10.8 1.7 8.8 1.2 4.1 3 0 0 3 3 3 0 MT0933-like antitoxin protein MFS_1 PF07690.11 GAP89803.1 - 1.5e-24 86.3 22.0 1.5e-24 86.3 15.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily O-antigen_lig PF13425.1 GAP89803.1 - 1.1 9.2 25.4 0.19 11.7 2.2 4.6 3 1 1 4 4 4 0 O-antigen ligase like membrane protein Amidohydro_4 PF13147.1 GAP89804.1 - 2.4e-07 31.0 0.2 2.6e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 GAP89804.1 - 2.1e-06 27.4 0.4 4.3e-06 26.4 0.3 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 GAP89804.1 - 2.7e-05 23.9 0.0 0.0013 18.4 0.1 2.2 2 0 0 2 2 2 1 Amidohydrolase family Glyco_hydro_16 PF00722.16 GAP89805.1 - 1.3e-12 47.3 0.1 3.6e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 HET PF06985.6 GAP89805.1 - 7e-05 23.0 0.7 0.00052 20.1 0.5 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GMC_oxred_N PF00732.14 GAP89806.1 - 1e-60 205.3 0.0 1.4e-60 204.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAP89806.1 - 1.7e-32 112.7 0.0 2.7e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAP89806.1 - 2.1e-09 36.7 0.1 0.00023 20.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAP89806.1 - 1.1e-05 24.5 0.0 0.00014 20.9 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 GAP89806.1 - 4.6e-05 23.3 0.4 0.00028 20.8 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAP89806.1 - 0.0012 17.7 0.0 0.24 10.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 GAP89806.1 - 0.0061 16.6 0.0 2.6 8.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAP89806.1 - 0.035 14.5 0.0 0.43 11.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAP89806.1 - 0.04 12.7 0.0 2.5 6.8 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A BolA PF01722.13 GAP89807.1 - 0.022 14.7 0.1 0.044 13.7 0.1 1.5 1 0 0 1 1 1 0 BolA-like protein 2-oxoacid_dh PF00198.18 GAP89808.1 - 2.9e-69 232.8 0.2 2.5e-68 229.7 0.2 2.1 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 GAP89808.1 - 1.8e-18 65.9 1.7 3.3e-18 65.0 1.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 GAP89808.1 - 0.0026 16.9 0.6 0.057 12.5 0.1 2.3 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 GAP89808.1 - 0.038 14.3 0.4 3 8.2 0.1 2.4 1 1 1 2 2 2 0 HlyD family secretion protein DUF2360 PF10152.4 GAP89808.1 - 1.2 9.4 9.2 2.5 8.4 6.4 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Neisseria_TspB PF05616.8 GAP89808.1 - 3.1 6.0 6.6 4 5.6 4.6 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Complex1_LYR PF05347.10 GAP89809.1 - 1.3e-08 34.5 3.0 1.8e-08 34.0 2.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAP89809.1 - 3.9e-06 26.9 1.7 5.5e-06 26.4 1.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like TPR_7 PF13176.1 GAP89809.1 - 0.15 11.9 0.5 0.93 9.4 0.0 2.2 2 1 0 2 2 2 0 Tetratricopeptide repeat Histone PF00125.19 GAP89810.1 - 8.5e-26 89.8 0.0 1.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 GAP89810.1 - 1.3e-05 25.1 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAP89811.1 - 8.6e-22 77.0 0.3 1.3e-21 76.5 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 GAP89811.1 - 3.3e-05 23.8 0.0 9.8e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 GAP89811.1 - 0.00021 21.5 0.0 0.00035 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 GAP89811.1 - 0.023 14.1 0.1 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Replication protein C N-terminal domain DUF1018 PF06252.7 GAP89811.1 - 0.028 14.9 0.4 0.037 14.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) R3H PF01424.17 GAP89812.1 - 6.7e-12 44.9 0.0 1.6e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 GAP89812.1 - 5.1e-10 38.9 0.7 1.2e-09 37.7 0.5 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 GAP89812.1 - 4.8e-06 26.3 0.7 3e-05 23.7 0.2 2.6 2 0 0 2 2 2 1 DExH-box splicing factor binding site Peptidase_C54 PF03416.14 GAP89813.1 - 2.2e-93 312.4 0.0 2.7e-93 312.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 DnaJ PF00226.26 GAP89814.1 - 7.5e-26 89.6 0.6 7.5e-26 89.6 0.4 2.5 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.3 GAP89814.1 - 8.9e-11 41.6 3.2 1e-09 38.2 1.9 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAP89814.1 - 3.5e-08 33.3 2.6 1.8e-07 31.0 1.7 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 GAP89814.1 - 6e-06 26.3 4.8 0.00044 20.3 1.5 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) RPT PF13446.1 GAP89814.1 - 0.0016 17.7 0.1 0.029 13.7 0.0 2.7 2 1 0 2 2 2 1 A repeated domain in UCH-protein zf-C2H2 PF00096.21 GAP89814.1 - 0.005 17.1 4.4 0.12 12.8 0.6 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP89814.1 - 0.011 16.0 2.4 0.49 10.8 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger PTS_IIB PF02302.12 GAP89814.1 - 0.42 11.1 2.7 0.57 10.6 0.2 2.4 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit zf-C2H2_6 PF13912.1 GAP89814.1 - 5.5 7.0 4.9 0.97 9.4 0.7 1.7 2 0 0 2 2 2 0 C2H2-type zinc finger Neur_chan_memb PF02932.11 GAP89814.1 - 7.8 6.3 9.0 1.6 8.5 3.4 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SPX PF03105.14 GAP89815.1 - 5.1e-32 111.7 0.0 6.8e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 SPX domain zf-C3HC4 PF00097.20 GAP89815.1 - 5e-07 29.2 9.6 5e-07 29.2 6.6 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAP89815.1 - 8.1e-07 28.7 10.9 1.7e-06 27.7 7.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAP89815.1 - 9.6e-07 28.7 11.1 1.9e-06 27.7 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAP89815.1 - 2e-06 27.5 9.1 2e-06 27.5 6.3 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 GAP89815.1 - 2.3e-06 27.2 8.0 5.5e-06 26.0 5.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 GAP89815.1 - 4.1e-06 26.3 7.2 7.7e-06 25.4 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAP89815.1 - 5.3e-06 26.0 6.3 5.3e-06 26.0 4.3 2.1 2 0 0 2 2 2 1 RING-type zinc-finger TerY-C PF15616.1 GAP89815.1 - 0.0034 17.3 0.2 0.0059 16.5 0.2 1.5 1 0 0 1 1 1 1 TerY-C metal binding domain zf-RING_6 PF14835.1 GAP89815.1 - 0.0061 16.3 2.4 0.019 14.7 1.7 1.8 1 0 0 1 1 1 1 zf-RING of BARD1-type protein ASFV_p27 PF06556.6 GAP89815.1 - 0.17 11.7 0.2 0.45 10.4 0.1 1.6 1 0 0 1 1 1 0 IAP-like protein p27 C-terminus zf-RING_4 PF14570.1 GAP89815.1 - 0.34 10.5 9.8 0.034 13.7 3.4 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain COG6 PF06419.6 GAP89818.1 - 1.1e-222 740.5 0.0 1.3e-222 740.3 0.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 RmuC PF02646.11 GAP89818.1 - 0.0022 16.8 2.9 0.0022 16.8 2.0 2.2 3 0 0 3 3 3 1 RmuC family COG2 PF06148.6 GAP89818.1 - 0.0079 16.0 1.8 0.032 14.0 0.7 2.5 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Pex2_Pex12 PF04757.9 GAP89818.1 - 0.13 11.6 4.9 1.4 8.2 0.1 3.0 3 1 1 4 4 4 0 Pex2 / Pex12 amino terminal region APG9 PF04109.11 GAP89819.1 - 7.5e-149 495.6 1.6 9.4e-149 495.3 1.1 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 DUF4131 PF13567.1 GAP89819.1 - 0.22 10.8 3.4 0.19 11.1 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Mito_carr PF00153.22 GAP89820.1 - 4.2e-71 234.7 8.2 4.2e-24 84.0 0.5 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Methyltransf_9 PF08003.6 GAP89820.1 - 0.17 10.5 0.0 0.28 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DnaJ PF00226.26 GAP89821.1 - 1.3e-23 82.4 1.1 1.3e-23 82.4 0.7 3.1 3 0 0 3 3 3 1 DnaJ domain TPR_11 PF13414.1 GAP89821.1 - 1.1e-16 60.2 6.7 3.9e-09 36.0 0.0 5.1 3 1 1 4 4 4 3 TPR repeat TPR_1 PF00515.23 GAP89821.1 - 1.2e-11 43.7 0.0 0.0017 17.8 0.0 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAP89821.1 - 1.8e-11 44.3 0.4 0.011 16.3 0.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 GAP89821.1 - 1.1e-10 41.1 0.1 0.0011 18.7 0.0 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAP89821.1 - 3.5e-10 39.0 4.2 0.048 13.5 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAP89821.1 - 1e-09 38.1 0.4 0.084 13.5 0.0 5.7 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAP89821.1 - 3e-09 36.0 0.0 0.0056 16.3 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAP89821.1 - 1.6e-05 25.1 1.4 0.11 12.7 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 GAP89821.1 - 5.3e-05 23.4 10.4 0.61 10.6 0.0 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAP89821.1 - 6.3e-05 22.8 0.7 0.015 15.4 0.0 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAP89821.1 - 0.00019 21.3 5.2 0.5 10.3 0.0 4.6 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAP89821.1 - 0.00075 19.1 0.2 0.35 10.7 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 GAP89821.1 - 0.0022 18.0 7.5 0.17 12.0 0.1 4.2 3 1 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF1217 PF06748.7 GAP89821.1 - 0.022 14.8 0.0 0.099 12.7 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1217) IFT46_B_C PF12317.3 GAP89821.1 - 0.098 12.0 0.1 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal TPR_4 PF07721.9 GAP89821.1 - 1.8 9.1 5.1 5.3 7.7 1.2 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat Reo_sigmaC PF04582.7 GAP89822.1 - 0.0018 17.5 0.4 0.0058 15.8 0.0 1.7 1 1 0 1 1 1 1 Reovirus sigma C capsid protein Vac14_Fig4_bd PF11916.3 GAP89824.1 - 3.4e-83 277.2 7.5 3.4e-83 277.2 5.2 2.0 3 0 0 3 3 3 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 GAP89824.1 - 4.9e-45 151.8 0.0 3.8e-43 145.8 0.0 3.4 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 GAP89824.1 - 2.1e-08 33.5 2.6 0.00039 20.2 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 GAP89824.1 - 2.6e-07 30.9 4.5 0.0017 18.7 0.0 5.4 5 1 1 6 6 6 2 HEAT-like repeat HEAT_2 PF13646.1 GAP89824.1 - 2.2e-06 27.8 0.7 0.023 14.9 0.0 4.5 4 0 0 4 4 4 2 HEAT repeats Cnd1 PF12717.2 GAP89824.1 - 2.5e-05 24.1 0.6 0.073 12.9 0.0 3.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 GAP89824.1 - 0.086 12.7 0.0 18 5.3 0.0 4.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat FA_desaturase PF00487.19 GAP89825.1 - 4.7e-34 117.9 29.5 1e-33 116.8 20.5 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 GAP89825.1 - 1.3e-09 37.7 0.0 2.2e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AAA PF00004.24 GAP89826.1 - 5.7e-39 133.3 0.0 1.6e-38 131.8 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAP89826.1 - 8.2e-06 25.9 0.8 0.00013 22.0 0.1 2.9 2 1 0 2 2 2 1 AAA domain Vps4_C PF09336.5 GAP89826.1 - 9.9e-06 25.3 0.0 0.00021 21.1 0.0 3.1 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 GAP89826.1 - 2.7e-05 23.3 0.0 5.3e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 GAP89826.1 - 0.0003 20.8 0.2 0.0054 16.7 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain TIP49 PF06068.8 GAP89826.1 - 0.00045 19.0 0.1 0.00078 18.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 GAP89826.1 - 0.0011 18.4 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 GAP89826.1 - 0.0012 18.2 1.4 0.35 10.2 0.1 3.4 2 1 2 4 4 4 1 AAA domain AAA_5 PF07728.9 GAP89826.1 - 0.0013 18.4 0.0 0.0051 16.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 GAP89826.1 - 0.0014 18.5 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 GAP89826.1 - 0.0037 16.4 0.1 0.0073 15.4 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 GAP89826.1 - 0.0053 16.4 0.1 0.023 14.4 0.0 2.1 2 0 0 2 2 1 1 Part of AAA domain AAA_11 PF13086.1 GAP89826.1 - 0.0094 15.5 0.0 0.033 13.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 GAP89826.1 - 0.011 15.6 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 GAP89826.1 - 0.015 15.2 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 GAP89826.1 - 0.016 14.1 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.1 GAP89826.1 - 0.024 15.4 0.1 0.11 13.3 0.0 2.2 3 0 0 3 3 1 0 AAA domain AAA_24 PF13479.1 GAP89826.1 - 0.024 14.1 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 GAP89826.1 - 0.057 13.3 0.3 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 GAP89826.1 - 0.071 12.7 0.0 0.23 11.0 0.0 1.9 1 0 0 1 1 1 0 NACHT domain Guanylate_kin PF00625.16 GAP89826.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase PhoH PF02562.11 GAP89826.1 - 0.16 11.1 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Arch_ATPase PF01637.13 GAP89826.1 - 0.18 11.4 0.0 0.38 10.3 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase Sigma54_activat PF00158.21 GAP89826.1 - 0.19 11.1 0.0 0.45 9.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Glyoxalase_2 PF12681.2 GAP89827.1 - 0.09 13.3 0.0 0.28 11.7 0.0 1.9 1 0 0 1 1 1 0 Glyoxalase-like domain CAP_N PF01213.14 GAP89827.1 - 0.63 9.2 16.6 0.032 13.5 5.5 2.7 1 1 1 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PAT1 PF09770.4 GAP89827.1 - 9.5 4.3 22.7 14 3.8 15.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EMG1 PF03587.9 GAP89828.1 - 2.7e-77 258.6 0.0 3.1e-77 258.4 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Glyco_hydro_25 PF01183.15 GAP89829.1 - 6.9e-41 140.0 0.1 7.9e-41 139.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 EamA PF00892.15 GAP89830.1 - 7e-24 84.2 27.6 9.2e-14 51.5 6.5 2.6 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 GAP89830.1 - 0.019 15.1 5.7 0.019 15.1 4.0 2.9 2 2 0 2 2 2 0 Multidrug resistance efflux transporter DUF3021 PF11457.3 GAP89830.1 - 2.8 7.8 10.7 1.9 8.4 1.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3021) Ribosomal_S17 PF00366.15 GAP89831.1 - 0.0026 17.7 0.3 0.0038 17.2 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 YbaB_DNA_bd PF02575.11 GAP89831.1 - 6.3 6.7 5.7 1.3 8.9 0.3 2.1 2 1 0 2 2 2 0 YbaB/EbfC DNA-binding family SGT1 PF07093.6 GAP89832.1 - 4.7e-140 467.7 17.5 2.1e-138 462.3 12.1 2.0 1 1 0 1 1 1 1 SGT1 protein SMC_N PF02463.14 GAP89833.1 - 3e-22 78.9 1.9 2.3e-21 76.0 1.3 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 GAP89833.1 - 4.8e-16 59.6 5.7 4.8e-16 59.6 3.9 5.5 2 2 1 3 3 2 1 AAA domain Laminin_II PF06009.7 GAP89833.1 - 3.2e-06 26.9 38.1 0.0036 17.0 0.5 6.1 4 2 2 6 6 6 5 Laminin Domain II AAA_21 PF13304.1 GAP89833.1 - 1.2e-05 25.4 2.0 0.00059 19.8 0.1 3.1 4 0 0 4 4 4 1 AAA domain SbcCD_C PF13558.1 GAP89833.1 - 6.7e-05 22.7 0.0 0.00039 20.2 0.0 2.3 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SMC_hinge PF06470.8 GAP89833.1 - 0.00012 21.9 0.0 0.00058 19.8 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.1 GAP89833.1 - 0.0012 18.2 0.0 0.0031 17.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 GAP89833.1 - 0.068 12.2 14.2 0.041 12.9 6.1 3.0 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 GAP89833.1 - 0.084 13.1 0.2 0.084 13.1 0.2 5.2 4 2 0 4 4 3 0 ABC transporter DUF4463 PF14703.1 GAP89833.1 - 0.11 13.0 0.2 0.11 13.0 0.1 4.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4463) Reo_sigmaC PF04582.7 GAP89833.1 - 0.29 10.2 12.0 0.42 9.7 1.0 4.0 4 1 0 4 4 4 0 Reovirus sigma C capsid protein IFT57 PF10498.4 GAP89833.1 - 0.85 8.2 53.5 0.014 14.1 2.2 5.3 3 1 1 5 5 5 0 Intra-flagellar transport protein 57 IncA PF04156.9 GAP89833.1 - 1.1 8.8 73.0 0.35 10.4 5.7 6.3 2 2 3 5 5 5 0 IncA protein COQ9 PF08511.6 GAP89834.1 - 7.6e-27 92.6 0.0 2e-26 91.2 0.0 1.7 2 0 0 2 2 2 1 COQ9 RRM_1 PF00076.17 GAP89835.1 - 7e-49 163.3 0.0 2e-15 56.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP89835.1 - 2.2e-40 136.4 0.0 5.5e-13 48.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP89835.1 - 1.1e-18 66.8 0.0 1.3e-05 24.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAP89835.1 - 0.00013 21.7 0.0 1.8 8.4 0.0 3.3 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.3 GAP89835.1 - 0.0011 18.6 0.2 1.3 8.8 0.0 3.8 3 2 0 3 3 3 1 Limkain b1 ATP-grasp_2 PF08442.5 GAP89835.1 - 0.002 17.5 0.0 0.037 13.3 0.0 2.7 3 0 0 3 3 3 1 ATP-grasp domain SRP14 PF02290.10 GAP89836.1 - 6.6e-23 80.4 0.0 9.7e-23 79.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle 14kD protein 2-Hacid_dh_C PF02826.14 GAP89837.1 - 7e-31 106.7 0.0 1e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MIF4G PF02854.14 GAP89838.1 - 1.8e-20 73.2 0.1 2.8e-20 72.6 0.1 1.3 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 GAP89838.1 - 6e-07 29.1 0.0 3e-05 23.6 0.0 2.4 2 0 0 2 2 2 1 MA3 domain GLE1 PF07817.8 GAP89838.1 - 0.049 12.5 0.7 0.71 8.7 0.1 2.5 2 0 0 2 2 2 0 GLE1-like protein DUF4105 PF13387.1 GAP89838.1 - 0.12 11.5 0.1 0.23 10.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) Pyr_redox_dim PF02852.17 GAP89839.1 - 1.9e-41 140.5 0.0 5.1e-41 139.1 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 GAP89839.1 - 3.2e-36 125.1 17.3 1.2e-35 123.1 12.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAP89839.1 - 3.9e-22 78.4 12.0 4.2e-20 71.9 0.6 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP89839.1 - 3.8e-10 39.6 4.2 1.4e-05 25.0 0.6 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 GAP89839.1 - 6e-10 38.5 10.5 7.8e-08 31.5 4.1 2.6 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.2 GAP89839.1 - 1.8e-09 37.2 7.6 2.1e-09 37.0 0.4 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAP89839.1 - 4.3e-08 32.4 10.0 2.9e-07 29.6 3.2 2.9 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.19 GAP89839.1 - 6.5e-08 31.8 15.7 7.3e-05 21.8 0.5 4.1 3 1 1 4 4 4 3 FAD dependent oxidoreductase Thi4 PF01946.12 GAP89839.1 - 1e-07 31.3 3.2 9.9e-06 24.8 0.2 2.4 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.9 GAP89839.1 - 2.5e-06 26.2 14.3 0.00018 20.0 2.0 4.1 4 0 0 4 4 4 1 HI0933-like protein Pyr_redox_3 PF13738.1 GAP89839.1 - 9.9e-06 25.7 7.6 0.044 13.8 3.4 3.5 1 1 2 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAP89839.1 - 2e-05 23.8 8.0 0.0024 16.9 0.6 2.6 2 1 0 2 2 2 2 FAD binding domain K_oxygenase PF13434.1 GAP89839.1 - 9.4e-05 21.4 0.3 0.41 9.5 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 GAP89839.1 - 0.00018 21.1 2.2 0.19 11.2 0.0 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 GAP89839.1 - 0.0016 17.4 1.4 0.01 14.8 0.0 2.4 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_7 PF13241.1 GAP89839.1 - 0.022 15.0 2.4 5.2 7.3 0.3 3.0 2 1 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 GAP89839.1 - 1 9.0 6.2 0.64 9.6 0.1 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 GAP89841.1 - 1.9e-31 108.8 0.0 3.2e-31 108.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 GAP89841.1 - 1.7e-30 105.8 0.0 3.5e-29 101.4 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme PP-binding PF00550.20 GAP89841.1 - 1.8e-08 34.4 0.6 4.4e-08 33.2 0.1 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.16 GAP89841.1 - 2.2e-08 33.8 0.0 3.8e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAP89841.1 - 1.5e-05 25.0 0.0 0.00027 20.8 0.0 2.8 3 1 0 3 3 3 1 short chain dehydrogenase AMP-binding_C PF13193.1 GAP89841.1 - 0.0094 16.8 0.0 0.14 13.1 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain KR PF08659.5 GAP89841.1 - 0.018 14.7 0.0 0.067 12.8 0.0 2.0 2 0 0 2 2 2 0 KR domain Semialdhyde_dh PF01118.19 GAP89841.1 - 0.049 13.9 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 GAP89841.1 - 0.087 11.7 0.0 0.19 10.6 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Cys_Met_Meta_PP PF01053.15 GAP89842.1 - 1.1e-24 86.5 0.0 1.2e-18 66.6 0.0 2.3 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme ORC6 PF05460.8 GAP89842.1 - 0.86 8.6 5.8 1.2 8.1 4.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) BAF1_ABF1 PF04684.8 GAP89842.1 - 3 6.5 5.2 5.4 5.7 3.6 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor THUMP PF02926.12 GAP89843.1 - 3.9e-12 46.2 0.4 7.5e-12 45.3 0.1 1.6 2 0 0 2 2 2 1 THUMP domain LCAT PF02450.10 GAP89844.1 - 7.2e-98 328.0 0.0 8.6e-98 327.8 0.0 1.0 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Acetyltransf_1 PF00583.19 GAP89845.1 - 4.1e-19 68.3 0.0 6.2e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAP89845.1 - 1.8e-10 40.9 0.0 2.7e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAP89845.1 - 3.2e-10 39.6 0.0 5.4e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 GAP89845.1 - 4.5e-10 39.5 0.0 6.4e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAP89845.1 - 3.7e-09 36.6 0.0 4.4e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAP89845.1 - 4.4e-08 33.4 0.0 5.3e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAP89845.1 - 4.8e-05 23.2 0.0 8.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAP89845.1 - 0.00099 18.9 0.0 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 GAP89845.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1917 PF08939.5 GAP89846.1 - 1.3e-58 198.6 0.0 2.7e-58 197.5 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1917) WD40 PF00400.27 GAP89847.1 - 6.5e-10 38.5 2.0 0.00075 19.2 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat Xpo1 PF08389.7 GAP89848.1 - 2.7e-07 30.6 0.1 4.9e-06 26.5 0.1 3.1 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.14 GAP89848.1 - 3.8e-06 26.7 1.3 2.7e-05 23.9 0.0 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain IFRD PF05004.8 GAP89848.1 - 0.018 14.1 0.0 0.039 13.0 0.0 1.5 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) HEAT PF02985.17 GAP89848.1 - 0.02 14.9 0.2 6.2 7.1 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.1 GAP89848.1 - 0.029 14.6 0.2 2.6 8.4 0.0 3.5 3 0 0 3 3 3 0 HEAT repeats DUF2013 PF09431.5 GAP89849.1 - 4.8e-50 168.9 3.9 8.4e-50 168.1 2.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) PH PF00169.24 GAP89850.1 - 2.2e-09 37.4 0.0 6.1e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 PH domain Prominin PF05478.6 GAP89850.1 - 0.019 12.4 0.1 0.029 11.9 0.1 1.2 1 0 0 1 1 1 0 Prominin Gar1 PF04410.9 GAP89851.1 - 2e-23 82.5 7.6 6.5e-21 74.3 0.0 3.1 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region TRI5 PF06330.6 GAP89852.1 - 1e-15 57.3 0.0 1.2e-15 57.0 0.0 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) DUF411 PF04214.8 GAP89855.1 - 0.11 12.0 0.1 4.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF TPP_enzyme_M PF00205.17 GAP89856.1 - 2.8e-28 98.3 0.1 4.9e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 GAP89856.1 - 1e-12 47.8 0.0 2.1e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.13 GAP89856.1 - 2.5e-06 27.1 0.3 0.023 14.1 0.0 2.7 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain E1-N PF14463.1 GAP89856.1 - 0.028 14.0 3.7 0.023 14.3 0.9 2.1 2 0 0 2 2 2 0 E1 N-terminal domain bcl-2I13 PF12201.3 GAP89856.1 - 0.079 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Bcl2-interacting killer, BH3-domain containing TPP_enzyme_N PF02776.13 GAP89857.1 - 1.4e-09 37.6 0.0 1.6e-09 37.4 0.0 1.0 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Evr1_Alr PF04777.8 GAP89858.1 - 1.4e-30 104.9 1.9 1.4e-29 101.8 0.5 2.0 2 0 0 2 2 2 1 Erv1 / Alr family HEM4 PF02602.10 GAP89859.1 - 2.6e-31 108.6 0.0 3.7e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD TLD PF07534.11 GAP89860.1 - 1.7e-20 73.4 0.0 2.3e-13 50.3 0.0 2.2 2 0 0 2 2 2 2 TLD M_domain PF12938.2 GAP89860.1 - 0.88 9.3 6.4 1.9 8.2 4.4 1.6 1 0 0 1 1 1 0 M domain of GW182 Pkinase PF00069.20 GAP89861.1 - 1.5e-74 250.4 0.0 2e-74 250.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP89861.1 - 8.4e-32 110.2 0.0 1.1e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP89861.1 - 0.00058 18.9 0.0 0.0011 17.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAP89861.1 - 0.002 17.1 0.1 0.0036 16.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAP89861.1 - 0.01 15.6 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 GAP89861.1 - 0.058 12.2 0.0 0.086 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Gag_p6 PF08705.6 GAP89861.1 - 0.078 13.0 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Gag protein p6 S_100 PF01023.14 GAP89861.1 - 0.1 11.9 0.3 0.36 10.2 0.2 1.9 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Sec23_trunk PF04811.10 GAP89862.1 - 1e-72 244.4 0.0 4.5e-72 242.3 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 GAP89862.1 - 5.7e-22 77.0 0.0 1.2e-20 72.8 0.0 2.5 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 GAP89862.1 - 1.6e-18 66.9 0.0 3.1e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 GAP89862.1 - 4.4e-18 64.5 5.3 7.6e-18 63.7 3.7 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 GAP89862.1 - 8.3e-10 38.2 0.0 1.8e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Orthopox_A36R PF05950.6 GAP89863.1 - 0.012 15.5 0.3 0.013 15.4 0.2 1.3 1 1 0 1 1 1 0 Orthopoxvirus A36R protein Fungal_trans_2 PF11951.3 GAP89864.1 - 1.1e-11 43.9 1.1 1.5e-11 43.5 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_C12 PF01088.16 GAP89867.1 - 9.4e-57 191.6 0.0 3e-56 189.9 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 ECM11 PF15463.1 GAP89867.1 - 0.03 14.5 0.1 0.083 13.1 0.1 1.7 1 0 0 1 1 1 0 Extracellular mutant protein 11 CDP-OH_P_transf PF01066.16 GAP89868.1 - 4.6e-14 52.5 1.7 4.6e-14 52.5 1.2 1.5 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Metallopep PF12044.3 GAP89869.1 - 6.9e-123 410.2 0.0 9.1e-123 409.8 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 GAP89869.1 - 4.2e-09 36.3 0.1 0.00015 21.6 0.1 2.3 1 1 1 2 2 2 2 Jacalin-like lectin domain Whi5 PF08528.6 GAP89870.1 - 8.7e-10 37.9 0.0 1.5e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Whi5 like DUF793 PF05633.6 GAP89870.1 - 0.015 14.0 0.4 0.021 13.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF793) Laminin_G_3 PF13385.1 GAP89871.1 - 2.4e-06 27.8 0.1 3.1e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Glyco_hydro_16 PF00722.16 GAP89871.1 - 8e-06 25.2 0.0 1.2e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Ank_2 PF12796.2 GAP89872.1 - 3.7e-78 257.9 0.1 2.2e-23 82.3 0.1 5.4 4 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAP89872.1 - 1.9e-61 200.9 0.0 7.1e-07 28.7 0.0 13.6 12 1 1 13 13 13 13 Ankyrin repeat Ank_4 PF13637.1 GAP89872.1 - 1.5e-48 162.3 0.0 5.6e-08 33.0 0.0 9.8 6 3 5 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP89872.1 - 9.8e-47 152.2 0.0 0.0022 18.0 0.0 13.4 13 0 0 13 13 13 11 Ankyrin repeat Ank_5 PF13857.1 GAP89872.1 - 9.2e-38 127.4 0.2 4.5e-07 29.9 0.0 11.3 3 3 8 12 12 12 10 Ankyrin repeats (many copies) HET PF06985.6 GAP89872.1 - 5.4e-16 59.0 2.3 5.1e-14 52.6 0.3 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Syndecan PF01034.15 GAP89874.1 - 0.24 11.0 0.3 0.5 10.0 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.10 GAP89874.1 - 0.24 10.9 0.0 0.47 10.0 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4328 PF14219.1 GAP89874.1 - 0.32 10.2 2.7 0.14 11.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) Peptidase_C14 PF00656.17 GAP89876.1 - 2e-72 243.8 0.0 2.6e-72 243.5 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Microtub_assoc PF07989.6 GAP89877.1 - 6e-28 96.4 4.7 6e-28 96.4 3.3 13.0 8 4 6 15 15 15 1 Microtubule associated Filament PF00038.16 GAP89877.1 - 5.7e-06 26.0 38.3 5.7e-06 26.0 26.5 8.9 2 1 7 9 9 9 4 Intermediate filament protein AAA_13 PF13166.1 GAP89877.1 - 6e-06 25.0 136.8 5.2e-05 21.9 16.8 6.5 1 1 4 6 6 6 4 AAA domain Reo_sigmaC PF04582.7 GAP89877.1 - 2.6e-05 23.5 61.0 0.0027 16.9 3.2 7.9 1 1 7 8 8 8 5 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 GAP89877.1 - 3e-05 21.9 21.3 3e-05 21.9 14.7 6.8 2 1 4 6 6 6 4 Myosin tail IncA PF04156.9 GAP89877.1 - 0.00021 20.9 220.8 0.032 13.8 14.1 10.3 1 1 8 9 9 6 3 IncA protein Tropomyosin_1 PF12718.2 GAP89877.1 - 0.00027 20.8 29.6 0.00027 20.8 20.5 10.6 1 1 10 11 11 10 4 Tropomyosin like ALIX_LYPXL_bnd PF13949.1 GAP89877.1 - 0.0015 17.5 14.1 0.0015 17.5 9.8 8.1 1 1 6 7 7 4 2 ALIX V-shaped domain binding to HIV TPR_MLP1_2 PF07926.7 GAP89877.1 - 0.0022 17.7 4.7 0.0022 17.7 3.3 11.2 2 1 8 12 12 12 4 TPR/MLP1/MLP2-like protein PACT_coil_coil PF10495.4 GAP89877.1 - 0.012 15.5 8.5 7.8 6.5 5.9 3.3 1 1 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein MscS_porin PF12795.2 GAP89877.1 - 0.067 12.5 203.5 0.0097 15.2 17.0 8.3 1 1 7 8 8 8 0 Mechanosensitive ion channel porin domain Spc7 PF08317.6 GAP89877.1 - 0.079 11.6 169.5 0.063 11.9 12.8 9.3 1 1 9 10 10 10 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.4 GAP89877.1 - 0.84 9.4 199.2 0.26 11.1 10.6 11.1 1 1 11 12 12 10 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 GAP89877.1 - 2.6 7.1 174.3 0.06 12.5 13.1 9.7 1 1 8 10 10 10 0 Growth-arrest specific micro-tubule binding MAD PF05557.8 GAP89877.1 - 9.1 4.2 179.1 0.18 9.8 64.2 4.4 1 1 3 4 4 4 0 Mitotic checkpoint protein Transglut_core2 PF13369.1 GAP89878.1 - 1.2e-12 47.6 0.0 2.3e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 GAP89878.1 - 2.8e-12 46.1 0.2 6.6e-12 44.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like YccV-like PF08755.6 GAP89878.1 - 2.9e-09 36.7 0.0 5.5e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like F-box PF00646.28 GAP89878.1 - 6.3e-07 28.8 0.3 3.2e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 F-box domain Elongin_A PF06881.6 GAP89878.1 - 0.063 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Nrap PF03813.9 GAP89879.1 - 1.7e-294 979.1 0.0 2e-294 978.9 0.0 1.0 1 0 0 1 1 1 1 Nrap protein DUF2805 PF10985.3 GAP89879.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) CoA_trans PF01144.18 GAP89880.1 - 2.1e-98 327.8 1.0 1.6e-58 197.4 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase adh_short PF00106.20 GAP89882.1 - 1.8e-14 53.9 0.1 3e-14 53.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP89882.1 - 0.00049 19.8 0.0 0.00072 19.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAP89882.1 - 0.027 13.8 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 GAP89882.1 - 0.05 13.1 1.0 0.11 12.0 0.1 2.0 3 0 0 3 3 3 0 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.3 GAP89882.1 - 0.083 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NACHT PF05729.7 GAP89883.1 - 3e-09 36.7 0.9 7.6e-08 32.1 0.1 3.1 3 0 0 3 3 2 1 NACHT domain AAA_22 PF13401.1 GAP89883.1 - 5.5e-06 26.5 0.5 0.00022 21.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAP89883.1 - 6e-06 26.3 6.3 0.00028 20.9 0.0 3.6 4 2 1 5 5 5 1 AAA ATPase domain Ank_2 PF12796.2 GAP89883.1 - 0.00028 21.1 0.3 0.001 19.3 0.1 2.1 2 0 0 2 2 1 1 Ankyrin repeats (3 copies) AAA_17 PF13207.1 GAP89883.1 - 0.0004 21.1 0.0 0.0024 18.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAP89883.1 - 0.0011 19.2 0.0 0.004 17.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 GAP89883.1 - 0.0019 18.5 1.6 0.0073 16.6 0.0 2.6 2 2 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 GAP89883.1 - 0.0048 16.3 0.3 0.012 15.1 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 GAP89883.1 - 0.007 15.8 0.0 0.037 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain AAA_14 PF13173.1 GAP89883.1 - 0.0093 15.8 0.0 0.54 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 GAP89883.1 - 0.019 15.1 0.4 0.1 12.7 0.0 2.5 3 0 0 3 3 2 0 RNA helicase ArgK PF03308.11 GAP89883.1 - 0.02 13.6 0.3 0.75 8.5 0.0 2.5 2 0 0 2 2 2 0 ArgK protein Zeta_toxin PF06414.7 GAP89883.1 - 0.022 13.8 0.1 0.07 12.2 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin Arch_ATPase PF01637.13 GAP89883.1 - 0.024 14.3 0.0 0.13 11.9 0.0 2.3 1 1 0 1 1 1 0 Archaeal ATPase AAA_28 PF13521.1 GAP89883.1 - 0.04 13.8 0.1 0.15 12.0 0.1 1.9 1 0 0 1 1 1 0 AAA domain Ank PF00023.25 GAP89883.1 - 0.055 13.3 0.4 0.28 11.0 0.0 2.5 3 0 0 3 3 1 0 Ankyrin repeat Viral_helicase1 PF01443.13 GAP89883.1 - 0.096 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 GAP89883.1 - 0.1 12.3 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 GAP89883.1 - 0.14 12.0 2.3 0.41 10.5 0.0 2.7 2 1 1 3 3 3 0 AAA domain MFS_1 PF07690.11 GAP89884.1 - 1.9e-23 82.7 74.2 5.8e-22 77.8 35.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1129 PF06570.6 GAP89884.1 - 0.15 11.3 4.3 0.15 11.3 1.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) 7TMR-DISM_7TM PF07695.6 GAP89884.1 - 0.96 9.0 37.0 8.4 6.0 9.5 3.8 1 1 2 3 3 3 0 7TM diverse intracellular signalling Ank_5 PF13857.1 GAP89885.1 - 0.00024 21.2 0.0 0.00072 19.7 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAP89885.1 - 0.00069 20.0 0.0 0.0018 18.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) CoaE PF01121.15 GAP89885.1 - 0.06 12.7 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase Ank_2 PF12796.2 GAP89885.1 - 0.065 13.5 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_2 PF12796.2 GAP89886.1 - 3.8e-92 302.7 6.7 1.2e-17 64.0 0.1 12.5 6 3 7 14 14 14 14 Ankyrin repeats (3 copies) Ank PF00023.25 GAP89886.1 - 1.2e-68 223.6 23.2 5.3e-07 29.1 0.0 20.2 21 0 0 21 21 21 10 Ankyrin repeat Ank_4 PF13637.1 GAP89886.1 - 2.3e-56 187.2 16.9 1.3e-09 38.2 0.0 15.1 15 2 2 17 17 17 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP89886.1 - 2.7e-56 181.8 18.8 4e-05 23.4 0.0 19.6 21 0 0 21 21 21 11 Ankyrin repeat Ank_5 PF13857.1 GAP89886.1 - 1.3e-52 174.6 20.9 3e-07 30.4 0.0 16.0 8 4 9 17 17 17 9 Ankyrin repeats (many copies) NACHT PF05729.7 GAP89886.1 - 2.9e-08 33.5 0.1 9.8e-08 31.8 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAP89886.1 - 0.0057 16.7 0.0 0.02 15.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 GAP89886.1 - 0.017 15.2 0.0 0.049 13.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase WWE PF02825.15 GAP89886.1 - 0.031 13.7 0.2 0.43 10.0 0.0 2.5 2 0 0 2 2 2 0 WWE domain DDE_1 PF03184.14 GAP89887.1 - 1.2e-39 135.7 0.0 2.3e-39 134.8 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 GAP89887.1 - 5.7e-06 25.7 0.0 1.1e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 GAP89887.1 - 0.00028 20.6 0.2 0.0019 17.9 0.0 2.5 2 1 1 3 3 3 1 Tc5 transposase DNA-binding domain HET PF06985.6 GAP89888.1 - 1e-25 90.5 0.0 1.7e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ketoacyl-synt PF00109.21 GAP89889.1 - 8.1e-74 248.2 0.0 2.1e-73 246.9 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAP89889.1 - 1.1e-37 130.0 0.0 4.9e-35 121.3 0.0 3.2 2 1 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAP89889.1 - 2.3e-33 114.5 0.5 7.1e-33 112.9 0.3 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 GAP89889.1 - 6.3e-29 101.0 0.0 1.1e-28 100.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.15 GAP89889.1 - 1.2e-14 55.0 0.0 3.4e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 GAP89889.1 - 1.1e-08 35.2 4.7 1.1e-08 35.2 3.3 2.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP89889.1 - 8.2e-07 28.8 1.1 0.00079 19.2 0.1 2.7 2 0 0 2 2 2 2 Alpha/beta hydrolase family PP-binding PF00550.20 GAP89889.1 - 2.4e-06 27.7 1.3 5.9e-06 26.4 0.9 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 GAP89889.1 - 0.00016 20.7 0.0 0.00029 19.8 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_1 PF00561.15 GAP89889.1 - 0.0009 18.8 0.0 0.0023 17.5 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 GAP89891.1 - 2e-22 79.8 0.2 2.8e-22 79.3 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 GAP89891.1 - 4.2e-16 58.5 0.0 5e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 GAP89891.1 - 0.00016 21.4 0.1 0.00029 20.6 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAP89891.1 - 0.01 15.4 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.16 GAP89891.1 - 0.038 13.2 0.0 0.09 11.9 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Methyltransf_31 PF13847.1 GAP89892.1 - 9.7e-09 34.9 0.0 1.3e-08 34.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP89892.1 - 2.2e-08 34.4 0.0 4e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP89892.1 - 3.3e-08 34.0 0.0 5.8e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP89892.1 - 1.6e-07 31.7 0.0 2.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP89892.1 - 2.1e-07 31.2 0.0 4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP89892.1 - 2.8e-05 24.1 0.2 7.1e-05 22.8 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP89892.1 - 0.00086 19.0 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP89892.1 - 0.0092 15.1 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 GAP89892.1 - 0.047 13.0 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Grp1_Fun34_YaaH PF01184.14 GAP89894.1 - 2.4e-28 98.8 25.3 3e-28 98.5 17.6 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family zf-CCCH PF00642.19 GAP89895.1 - 1.2e-10 40.8 8.5 9.4e-06 25.1 1.4 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 GAP89895.1 - 0.039 13.9 16.0 0.3 11.1 2.9 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type NACHT PF05729.7 GAP89896.1 - 7.6e-09 35.4 0.2 2e-08 34.0 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 GAP89896.1 - 1.9e-05 24.7 0.2 0.00017 21.6 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 GAP89896.1 - 0.00045 19.1 0.9 0.0021 16.9 0.0 2.2 1 1 0 2 2 2 1 NB-ARC domain Arch_ATPase PF01637.13 GAP89896.1 - 0.00084 19.1 0.1 0.0033 17.1 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 GAP89896.1 - 0.014 15.5 0.5 1.3 9.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 GAP89896.1 - 0.15 11.8 0.0 0.39 10.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain SNF2_N PF00176.18 GAP89897.1 - 2.3e-60 203.9 0.0 3.5e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 GAP89897.1 - 4.5e-06 26.6 0.0 1.6e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 GAP89897.1 - 0.035 13.9 0.0 0.17 11.7 0.0 2.1 1 1 1 2 2 2 0 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 GAP89897.1 - 0.95 9.2 5.5 2.4 7.9 3.8 1.7 1 0 0 1 1 1 0 zinc-RING finger domain MFS_1 PF07690.11 GAP89898.1 - 3e-14 52.5 67.1 9.4e-09 34.4 26.9 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 GAP89898.1 - 3.1e-08 32.2 17.6 3.1e-08 32.2 12.2 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.20 GAP89899.1 - 1.3e-28 100.0 1.8 1.3e-28 100.0 1.3 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP89899.1 - 2.5e-27 96.2 0.0 2.9e-27 95.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP89899.1 - 2.2e-09 37.2 0.1 4.8e-09 36.1 0.1 1.6 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAP89899.1 - 0.0028 17.1 0.6 0.0053 16.2 0.4 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 GAP89899.1 - 0.19 11.3 1.4 0.3 10.7 1.0 1.4 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RicinB_lectin_2 PF14200.1 GAP89900.1 - 0.0078 16.5 0.2 0.24 11.7 0.1 2.7 2 1 1 3 3 3 1 Ricin-type beta-trefoil lectin domain-like SH2 PF00017.19 GAP89900.1 - 0.082 12.7 0.0 0.24 11.2 0.0 1.8 2 0 0 2 2 2 0 SH2 domain Herpes_capsid PF06112.6 GAP89900.1 - 4.7 7.2 7.0 9.4 6.2 4.9 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein HET PF06985.6 GAP89901.1 - 1.1e-21 77.4 0.0 2.7e-21 76.1 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Baculo_PEP_C PF04513.7 GAP89903.1 - 0.31 10.8 3.1 6.2 6.6 0.4 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pkinase PF00069.20 GAP89904.1 - 0.0018 17.4 0.0 0.0051 15.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 GAP89904.1 - 0.095 12.4 0.2 0.44 10.2 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family PI-PLC-X PF00388.14 GAP89907.1 - 3.5e-54 182.1 0.0 5.6e-54 181.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 GAP89907.1 - 3.2e-37 127.1 0.4 5.3e-37 126.3 0.3 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain RabGAP-TBC PF00566.13 GAP89908.1 - 5.6e-47 159.9 0.0 9.8e-47 159.1 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.1 GAP89908.1 - 3.8e-05 23.7 0.1 0.00038 20.5 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 GAP89908.1 - 7.3e-05 22.3 0.5 0.014 15.2 0.2 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 GAP89908.1 - 0.018 14.3 0.1 0.21 11.0 0.2 2.8 3 0 0 3 3 3 0 EF hand NOA36 PF06524.7 GAP89908.1 - 0.024 13.9 4.8 0.051 12.8 3.3 1.4 1 0 0 1 1 1 0 NOA36 protein EF-hand_5 PF13202.1 GAP89908.1 - 0.032 13.5 0.7 0.16 11.3 0.5 2.2 2 0 0 2 2 2 0 EF hand GRAM PF02893.15 GAP89908.1 - 0.099 12.1 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 GRAM domain BSP_II PF05432.6 GAP89908.1 - 1.4 8.1 11.7 0.0082 15.4 2.1 1.6 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Myc_N PF01056.13 GAP89908.1 - 1.8 7.6 9.2 0.037 13.1 1.2 1.9 3 0 0 3 3 3 0 Myc amino-terminal region Pkinase PF00069.20 GAP89909.1 - 7.7e-64 215.3 0.0 9.3e-64 215.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP89909.1 - 2.7e-32 111.8 0.0 4.4e-32 111.1 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP89909.1 - 4.7e-05 22.4 0.0 6.1e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAP89909.1 - 0.0016 18.1 0.1 0.013 15.2 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF2694 PF10904.3 GAP89909.1 - 0.037 14.0 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2694) Seadorna_VP7 PF07387.6 GAP89909.1 - 0.059 12.2 0.0 0.089 11.6 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 zf-RING_2 PF13639.1 GAP89911.1 - 1.5e-13 50.2 5.7 2.5e-13 49.6 3.9 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 GAP89911.1 - 5.7e-13 48.4 0.0 1.4e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.2 GAP89911.1 - 3.3e-09 36.7 2.0 6e-09 35.8 1.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 GAP89911.1 - 4.9e-09 36.0 5.3 8.2e-09 35.3 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAP89911.1 - 1.1e-08 34.6 2.7 1.7e-08 33.9 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAP89911.1 - 9.9e-08 31.5 3.1 1.5e-07 30.9 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAP89911.1 - 3.5e-07 29.8 2.2 5.7e-07 29.1 1.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 GAP89911.1 - 0.0013 18.5 1.0 0.0024 17.6 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 GAP89911.1 - 0.044 13.6 3.8 0.19 11.6 2.8 1.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 GAP89911.1 - 0.13 12.0 2.6 0.28 10.9 1.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 GAP89911.1 - 0.13 12.2 2.1 0.33 10.9 1.4 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 GAP89911.1 - 0.13 12.3 3.3 0.25 11.4 2.3 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.6 GAP89911.1 - 0.22 11.5 3.5 0.4 10.7 2.4 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 GAP89911.1 - 0.3 10.7 2.4 0.64 9.6 1.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 GAP89911.1 - 1.1 8.9 2.6 2 8.1 1.8 1.4 1 0 0 1 1 1 0 PHD-finger EI24 PF07264.6 GAP89912.1 - 7.1e-06 25.6 10.2 1.8e-05 24.2 7.1 1.7 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Ish1 PF10281.4 GAP89912.1 - 0.034 14.2 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein ATP-sulfurylase PF01747.12 GAP89914.1 - 3e-88 294.7 0.0 4.1e-88 294.2 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 GAP89914.1 - 1.3e-57 193.8 0.0 2e-57 193.2 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 GAP89914.1 - 5.6e-53 178.6 0.0 9.1e-53 177.9 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain DUF937 PF06078.6 GAP89914.1 - 0.022 15.0 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF937) AAA_33 PF13671.1 GAP89914.1 - 0.1 12.4 0.1 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 GAP89914.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 HsbA PF12296.3 GAP89916.1 - 0.0034 17.2 1.1 0.0087 15.9 0.2 2.1 1 1 1 2 2 2 1 Hydrophobic surface binding protein A ARPC4 PF05856.7 GAP89917.1 - 4.4e-76 254.0 4.5 4.9e-76 253.8 3.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) UCH PF00443.24 GAP89918.1 - 8.8e-55 185.6 0.0 1.1e-54 185.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAP89918.1 - 1.6e-17 63.9 0.0 3.4e-17 62.8 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 GAP89918.1 - 6.3e-08 31.9 0.0 1.3e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 GAP89918.1 - 0.013 15.6 0.0 0.036 14.3 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain Tmemb_161AB PF10268.4 GAP89918.1 - 0.18 10.2 0.3 0.34 9.3 0.2 1.3 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB DUF3702 PF12486.3 GAP89919.1 - 0.059 13.0 3.1 3.4 7.3 0.1 2.1 1 1 1 2 2 2 0 ImpA domain protein FTR1 PF03239.9 GAP89919.1 - 0.084 11.8 0.0 0.095 11.6 0.0 1.1 1 0 0 1 1 1 0 Iron permease FTR1 family GBP_C PF02841.9 GAP89919.1 - 0.67 9.0 3.8 0.85 8.7 2.6 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Methyltransf_23 PF13489.1 GAP89920.1 - 1.4e-15 57.3 0.2 2.1e-15 56.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP89920.1 - 4e-15 55.6 0.0 6.9e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP89920.1 - 1.3e-13 51.4 0.0 2.3e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP89920.1 - 5.4e-13 49.2 0.0 9.7e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP89920.1 - 8.9e-11 42.0 0.0 6.2e-10 39.3 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP89920.1 - 1.3e-10 41.6 0.0 2.6e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP89920.1 - 2.2e-06 26.9 0.0 3.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 GAP89920.1 - 5.4e-05 23.1 0.0 0.00023 21.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 GAP89920.1 - 0.001 18.7 0.0 0.0022 17.6 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 GAP89920.1 - 0.0092 15.3 0.0 0.015 14.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 GAP89920.1 - 0.13 10.9 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PCMT PF01135.14 GAP89920.1 - 0.18 11.3 0.0 0.48 9.9 0.0 1.7 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Zn_clus PF00172.13 GAP89921.1 - 9.1e-09 35.0 7.4 1.3e-08 34.5 5.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GAT PF03127.9 GAP89923.1 - 2.6e-17 62.6 0.6 5.2e-17 61.6 0.1 1.8 2 0 0 2 2 2 1 GAT domain VHS PF00790.14 GAP89923.1 - 2e-05 24.2 0.0 0.0001 21.9 0.0 2.0 2 0 0 2 2 2 1 VHS domain Cas_APE2256 PF09651.5 GAP89923.1 - 0.051 13.2 0.2 5.5 6.6 0.0 2.8 2 1 1 3 3 3 0 CRISPR-associated protein (Cas_APE2256) SET PF00856.23 GAP89924.1 - 3.6e-20 72.8 0.8 3.6e-20 72.8 0.6 2.7 3 1 0 3 3 3 1 SET domain dCMP_cyt_deam_1 PF00383.17 GAP89925.1 - 1.8e-19 69.2 0.0 3.2e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 GAP89925.1 - 0.00053 19.8 0.3 0.011 15.6 0.2 2.5 1 1 0 1 1 1 1 Bd3614-like deaminase Pec_lyase_C PF00544.14 GAP89926.1 - 6.2e-18 65.0 4.3 1.1e-17 64.1 3.0 1.4 1 0 0 1 1 1 1 Pectate lyase Zn_clus PF00172.13 GAP89927.1 - 0.035 14.0 8.1 0.076 12.9 5.6 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2439 PF10382.4 GAP89929.1 - 8.2e-27 93.2 0.0 1.7e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) SH3_1 PF00018.23 GAP89930.1 - 6.9e-14 50.9 0.3 1.2e-13 50.1 0.2 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAP89930.1 - 9.4e-12 44.3 0.1 2e-11 43.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAP89930.1 - 2.1e-09 36.7 0.1 4.5e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.13 GAP89930.1 - 2.1e-09 37.2 1.0 1.2e-08 34.7 0.4 2.0 2 0 0 2 2 2 1 BAR domain DUF3450 PF11932.3 GAP89930.1 - 0.071 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Seryl_tRNA_N PF02403.17 GAP89930.1 - 0.12 12.4 2.1 0.098 12.6 0.5 1.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MARVEL PF01284.18 GAP89932.1 - 3.5e-05 23.6 15.7 0.00098 18.9 7.1 2.3 2 1 0 2 2 2 2 Membrane-associating domain VIT1 PF01988.14 GAP89932.1 - 0.082 12.3 9.1 0.0092 15.4 3.3 1.6 1 1 1 2 2 2 0 VIT family DUF4231 PF14015.1 GAP89932.1 - 1.3 9.0 4.1 1.6 8.7 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) DUF2518 PF10726.4 GAP89932.1 - 1.4 8.4 4.9 1.2 8.7 2.2 1.6 1 1 1 2 2 2 0 Protein of function (DUF2518) Col_cuticle_N PF01484.12 GAP89932.1 - 5 6.8 5.9 0.65 9.7 0.8 2.1 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Bot1p PF12298.3 GAP89934.1 - 9e-47 159.2 0.4 1.9e-46 158.1 0.2 1.6 1 1 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Response_reg PF00072.19 GAP89935.1 - 1.7e-20 73.0 0.0 2.7e-13 49.8 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain RRM_6 PF14259.1 GAP89936.1 - 0.072 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PX PF00787.19 GAP89937.1 - 5.5e-25 87.3 0.0 7.7e-25 86.8 0.0 1.2 1 0 0 1 1 1 1 PX domain DUF236 PF03057.9 GAP89937.1 - 0.018 14.9 0.0 0.093 12.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function Mito_carr PF00153.22 GAP89938.1 - 3.8e-71 234.8 0.2 1.5e-22 79.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CRF PF00473.12 GAP89938.1 - 0.0081 16.2 2.3 3.9 7.6 0.1 3.2 3 0 0 3 3 3 2 Corticotropin-releasing factor family Glyoxalase_2 PF12681.2 GAP89939.1 - 1.9e-14 54.1 0.1 2.3e-14 53.9 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 GAP89939.1 - 1.7e-12 47.4 0.0 2.4e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 GAP89939.1 - 2.3e-05 24.3 0.1 0.00015 21.7 0.1 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 GAP89939.1 - 0.011 15.6 0.0 1.2 8.9 0.0 2.1 1 1 0 2 2 2 0 Glyoxalase-like domain Zn_clus PF00172.13 GAP89940.1 - 0.00022 21.0 12.2 0.00035 20.4 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MreB_Mbl PF06723.8 GAP89941.1 - 0.017 13.7 0.0 0.022 13.3 0.0 1.1 1 0 0 1 1 1 0 MreB/Mbl protein Pkinase PF00069.20 GAP89942.1 - 7.9e-06 25.2 0.0 1.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain UBA_4 PF14555.1 GAP89943.1 - 6.5e-09 35.1 0.2 1.9e-08 33.6 0.2 1.8 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 GAP89943.1 - 3.4e-08 33.4 0.0 6.8e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 UBX domain Macoilin PF09726.4 GAP89943.1 - 1.8 6.7 8.6 2.5 6.2 5.9 1.1 1 0 0 1 1 1 0 Transmembrane protein PRP21_like_P PF12230.3 GAP89944.1 - 1.6e-60 204.4 18.8 1.8e-59 201.0 12.2 2.7 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 GAP89944.1 - 6e-37 125.0 0.9 1.4e-18 66.2 0.0 2.4 2 0 0 2 2 2 2 Surp module YwqJ-deaminase PF14431.1 GAP89944.1 - 0.14 12.0 3.1 2.2 8.1 0.2 3.0 3 0 0 3 3 3 0 YwqJ-like deaminase NinF PF05810.7 GAP89944.1 - 0.17 11.7 1.7 9.7 6.0 0.1 2.5 2 0 0 2 2 2 0 NinF protein PMT PF02366.13 GAP89946.1 - 4.7e-75 252.1 17.5 4.7e-75 252.1 12.1 2.1 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 GAP89946.1 - 3e-54 183.4 0.3 4.8e-54 182.7 0.2 1.3 1 0 0 1 1 1 1 MIR domain Pkinase PF00069.20 GAP89948.1 - 4e-23 81.8 0.0 5.2e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP89948.1 - 1e-10 41.1 0.0 5.6e-10 38.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase GFA PF04828.9 GAP89949.1 - 4.4e-20 71.4 10.7 4.2e-09 36.2 1.2 3.8 4 0 0 4 4 4 3 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_60s PF00428.14 GAP89949.1 - 0.25 11.7 5.6 0.43 11.0 3.9 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pkinase PF00069.20 GAP89950.1 - 4e-17 62.2 0.0 1e-16 60.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP89950.1 - 1.1e-10 41.0 0.0 0.00015 20.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Herpes_gE PF02480.11 GAP89953.1 - 0.029 12.6 0.0 0.043 12.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 GAP89953.1 - 0.043 13.5 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family adh_short PF00106.20 GAP89954.1 - 2.2e-15 56.9 3.0 4.3e-15 56.0 2.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP89954.1 - 8.7e-08 32.0 0.7 1.4e-07 31.3 0.5 1.3 1 0 0 1 1 1 1 KR domain HET PF06985.6 GAP89955.1 - 1.7e-21 76.8 5.2 4.3e-18 65.8 0.3 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ribosomal_L44 PF00935.14 GAP89957.1 - 2.9e-34 116.8 11.8 4.1e-34 116.4 8.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Pkinase PF00069.20 GAP89959.1 - 5.5e-54 183.0 0.0 7.9e-54 182.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP89959.1 - 1.2e-25 90.0 0.1 8.2e-25 87.3 0.1 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase ISN1 PF06437.6 GAP89960.1 - 1.9e-187 623.0 0.0 2.1e-187 622.8 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Gly_rich PF12810.2 GAP89961.1 - 1 8.8 7.5 1.1 8.7 5.2 1.1 1 0 0 1 1 1 0 Glycine rich protein IBN_N PF03810.14 GAP89962.1 - 3.5e-13 49.2 0.8 2.1e-09 37.1 0.0 4.2 4 0 0 4 4 4 2 Importin-beta N-terminal domain Cse1 PF08506.5 GAP89962.1 - 5.4e-08 31.8 0.1 1.6e-06 26.9 0.0 2.3 2 0 0 2 2 2 1 Cse1 HEAT_2 PF13646.1 GAP89962.1 - 3.3e-05 24.0 0.8 0.45 10.8 0.0 3.4 2 1 1 3 3 3 3 HEAT repeats Xpo1 PF08389.7 GAP89962.1 - 6.1e-05 22.9 3.4 0.0063 16.4 0.0 4.2 4 0 0 4 4 4 1 Exportin 1-like protein HEAT PF02985.17 GAP89962.1 - 0.055 13.5 0.5 0.89 9.8 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat HEAT_EZ PF13513.1 GAP89962.1 - 0.25 11.8 3.6 21 5.7 0.0 4.7 3 1 0 3 3 3 0 HEAT-like repeat IMS PF00817.15 GAP89965.1 - 7e-43 145.9 0.0 4.9e-42 143.2 0.0 2.1 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 GAP89965.1 - 2.1e-11 43.8 0.0 5.1e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 GAP89965.1 - 0.00041 20.2 0.0 0.001 18.9 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif zf-DHHC PF01529.15 GAP89966.1 - 6.7e-27 93.9 0.1 6.7e-27 93.9 0.1 1.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase COX4_pro_2 PF07835.7 GAP89966.1 - 0.02 14.8 0.5 0.02 14.8 0.4 2.7 4 0 0 4 4 4 0 Bacterial aa3 type cytochrome c oxidase subunit IV Peptidase_S8 PF00082.17 GAP89968.1 - 4e-43 147.5 8.0 6.1e-43 146.9 5.5 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 GAP89968.1 - 1.6e-09 38.2 0.2 2.9e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 TraP PF07296.6 GAP89968.1 - 0.14 11.1 0.0 0.88 8.5 0.0 2.1 2 0 0 2 2 2 0 TraP protein Dioxygenase_C PF00775.16 GAP89971.1 - 3.4e-51 173.1 0.0 4.7e-51 172.6 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 GAP89971.1 - 8.8e-15 54.4 0.0 1.9e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Catechol dioxygenase N terminus DUF2052 PF09747.4 GAP89972.1 - 2.2e-24 86.3 4.7 1.3e-23 83.8 3.3 1.9 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) pKID PF02173.12 GAP89972.1 - 0.068 12.4 2.0 0.24 10.6 1.4 1.9 1 0 0 1 1 1 0 pKID domain DUF605 PF04652.11 GAP89972.1 - 5.9 6.1 6.9 8.6 5.6 4.8 1.2 1 0 0 1 1 1 0 Vta1 like DUF2293 PF10056.4 GAP89973.1 - 1.1e-27 95.8 0.1 1.1e-27 95.8 0.0 2.8 4 0 0 4 4 4 1 Uncharacterized conserved protein (DUF2293) DUF4658 PF15555.1 GAP89973.1 - 0.082 12.7 4.3 0.088 12.6 1.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4658) ABM PF03992.11 GAP89974.1 - 0.017 15.1 0.1 0.5 10.4 0.0 2.4 2 1 0 2 2 2 0 Antibiotic biosynthesis monooxygenase K_trans PF02705.11 GAP89975.1 - 2.1e-175 584.1 16.1 2.5e-175 583.8 11.2 1.0 1 0 0 1 1 1 1 K+ potassium transporter ING PF12998.2 GAP89976.1 - 0.056 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding YjeF_N PF03853.10 GAP89978.1 - 8.9e-36 123.0 0.0 1.4e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 GAP89978.1 - 5.9e-12 46.0 0.0 2e-11 44.3 0.0 1.9 1 0 0 1 1 1 1 FDF domain PT PF04886.7 GAP89978.1 - 0.0014 17.8 14.8 0.0014 17.8 10.3 3.2 3 0 0 3 3 3 1 PT repeat Zn_clus PF00172.13 GAP89979.1 - 2.1e-07 30.7 11.8 3.5e-07 30.0 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YEATS PF03366.11 GAP89980.1 - 7.1e-24 83.3 0.5 1.3e-23 82.5 0.3 1.4 1 0 0 1 1 1 1 YEATS family C1q PF00386.16 GAP89980.1 - 0.21 11.6 1.2 0.46 10.4 0.2 1.9 1 1 1 2 2 2 0 C1q domain SAM_2 PF07647.12 GAP89981.1 - 2.1e-14 53.1 0.0 3.9e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 GAP89981.1 - 1.2e-13 51.3 0.0 2.2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.25 GAP89981.1 - 1.1e-12 47.9 0.0 2e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF745 PF05335.8 GAP89981.1 - 0.15 11.5 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Aminotran_1_2 PF00155.16 GAP89982.1 - 4.6e-58 196.9 0.0 6.9e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAP89982.1 - 0.00032 19.9 0.0 0.00063 18.9 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 GAP89982.1 - 0.018 13.8 0.0 0.028 13.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 GAP89982.1 - 0.14 10.4 0.0 0.21 9.8 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme AMP-binding PF00501.23 GAP89983.1 - 2.9e-51 174.1 0.0 3.4e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAP89983.1 - 8e-05 23.5 0.0 0.00031 21.6 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain A_deaminase PF00962.17 GAP89984.1 - 2.7e-34 118.5 0.0 3.8e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_3 PF07969.6 GAP89984.1 - 0.02 14.1 0.1 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase family WD40 PF00400.27 GAP89985.1 - 1.1e-47 158.2 20.8 9.1e-10 38.0 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 GAP89985.1 - 0.00013 21.7 0.0 0.063 12.9 0.0 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Mnd1 PF03962.10 GAP89985.1 - 0.47 10.0 2.7 0.73 9.4 1.9 1.2 1 0 0 1 1 1 0 Mnd1 family Phosducin PF02114.11 GAP89986.1 - 2.7e-14 52.5 0.0 1.9e-12 46.4 0.0 2.4 1 1 0 1 1 1 1 Phosducin SCA7 PF08313.7 GAP89988.1 - 5.9e-35 118.7 0.4 1.8e-34 117.1 0.2 1.8 1 0 0 1 1 1 1 SCA7, zinc-binding domain CDC45 PF02724.9 GAP89988.1 - 0.79 7.6 9.3 0.94 7.4 6.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 GAP89988.1 - 0.85 8.2 23.3 0.036 12.7 11.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Mito_carr PF00153.22 GAP89989.1 - 2.6e-41 139.2 0.0 3.1e-13 49.2 0.1 4.4 4 1 0 4 4 4 4 Mitochondrial carrier protein zf-C3HC4_2 PF13923.1 GAP89990.1 - 4.1e-08 33.0 12.6 0.00025 20.9 1.8 2.7 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAP89990.1 - 2.3e-06 27.1 12.5 4.1e-05 23.1 2.3 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 GAP89990.1 - 5.2e-06 25.8 0.8 5.2e-06 25.8 0.6 2.8 2 1 1 3 3 3 1 Rtf2 RING-finger zf-C3HC4 PF00097.20 GAP89990.1 - 3.4e-05 23.4 13.4 0.0036 16.9 0.5 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAP89990.1 - 7.4e-05 22.4 11.8 0.0011 18.7 2.4 2.6 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.1 GAP89990.1 - 0.00021 20.9 13.6 0.00029 20.4 3.1 3.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 GAP89990.1 - 0.00048 19.7 2.1 0.00048 19.7 1.4 2.8 2 0 0 2 2 2 1 RING-type zinc-finger FYVE PF01363.16 GAP89990.1 - 0.0017 18.1 8.8 0.013 15.4 1.8 2.9 2 1 0 2 2 2 1 FYVE zinc finger zf-C3HC4_4 PF15227.1 GAP89990.1 - 0.0083 15.9 13.9 0.25 11.2 1.2 2.9 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING DZR PF12773.2 GAP89990.1 - 1.1 9.1 12.2 0.94 9.3 1.5 3.5 3 0 0 3 3 3 0 Double zinc ribbon Vps39_2 PF10367.4 GAP89990.1 - 1.3 9.2 4.3 0.45 10.7 0.5 2.2 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Borrelia_P83 PF05262.6 GAP89990.1 - 2.5 6.2 9.8 3.7 5.7 6.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Acyltransferase PF01553.16 GAP89991.1 - 1.3e-11 44.0 0.0 2e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Pkinase PF00069.20 GAP89992.1 - 1.4e-76 257.0 0.0 1.7e-76 256.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP89992.1 - 2.6e-37 128.3 0.0 3.6e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP89992.1 - 0.0056 15.6 0.0 0.019 13.9 0.0 1.8 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 GAP89992.1 - 0.1 12.3 0.5 0.28 10.8 0.0 1.9 3 0 0 3 3 3 0 Phosphotransferase enzyme family Septin PF00735.13 GAP89993.1 - 3.6e-14 52.4 0.0 2.5e-13 49.6 0.0 1.9 1 1 0 1 1 1 1 Septin GTP_EFTU PF00009.22 GAP89993.1 - 9e-05 21.9 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAP89993.1 - 0.00076 19.4 0.0 0.0019 18.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAP89993.1 - 0.0075 16.7 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein UPF0079 PF02367.12 GAP89993.1 - 0.036 13.6 0.0 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PAP_central PF04928.12 GAP89994.1 - 1.3e-102 341.9 0.0 1.8e-102 341.5 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 GAP89994.1 - 8.7e-45 152.0 0.6 4.1e-44 149.8 0.1 2.0 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 GAP89994.1 - 2.5e-07 30.9 0.0 5.8e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain WAC_Acf1_DNA_bd PF10537.4 GAP89995.1 - 2.7e-39 133.4 0.0 7.7e-39 131.9 0.0 1.8 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 GAP89995.1 - 3.4e-18 65.1 0.2 5.8e-18 64.4 0.2 1.4 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 GAP89995.1 - 1.5e-12 46.8 0.4 3e-12 45.9 0.2 1.5 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 GAP89995.1 - 0.0035 17.2 0.2 0.0093 15.8 0.1 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM3 PF15614.1 GAP89995.1 - 0.0086 15.8 0.1 0.023 14.4 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 SDA1 PF05285.7 GAP89995.1 - 9.8 5.3 20.1 6.7 5.8 3.5 2.4 2 0 0 2 2 2 0 SDA1 Alg6_Alg8 PF03155.10 GAP89996.1 - 3e-144 481.3 32.6 3.8e-144 481.0 22.6 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Bromodomain PF00439.20 GAP89997.1 - 2.1e-23 82.0 0.3 4.2e-23 81.0 0.2 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 GAP89997.1 - 6.4e-10 39.0 0.4 1.4e-09 37.9 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAP89997.1 - 3.9e-09 36.4 0.1 1.1e-08 34.9 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Lectin_leg-like PF03388.8 GAP89998.1 - 1e-20 73.8 0.0 2.8e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 Legume-like lectin family Hemerythrin PF01814.18 GAP89998.1 - 0.098 12.8 0.1 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain BAF1_ABF1 PF04684.8 GAP89998.1 - 0.29 9.9 21.6 0.39 9.5 15.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF1664 PF07889.7 GAP89998.1 - 0.53 10.0 9.0 0.15 11.8 2.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) SPX PF03105.14 GAP89998.1 - 6.3 6.4 19.2 10 5.7 13.3 1.2 1 0 0 1 1 1 0 SPX domain TMEM51 PF15345.1 GAP89998.1 - 6.9 6.3 10.3 6.3 6.4 6.1 1.7 2 0 0 2 2 2 0 Transmembrane protein 51 Peptidase_M24 PF00557.19 GAP89999.1 - 7.7e-56 188.9 0.1 1e-55 188.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 GAP89999.1 - 5.8e-21 74.2 0.0 1.6e-20 72.8 0.0 1.7 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain AD PF09793.4 GAP89999.1 - 0.009 15.8 0.0 0.099 12.4 0.0 2.2 2 0 0 2 2 2 1 Anticodon-binding domain Fungal_trans PF04082.13 GAP90000.1 - 3.7e-33 114.5 0.0 5.7e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP90000.1 - 4e-11 42.6 13.8 6.6e-11 41.9 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Band_7 PF01145.20 GAP90000.1 - 0.13 12.1 2.2 1.3 8.8 0.9 2.3 2 0 0 2 2 2 0 SPFH domain / Band 7 family DPM3 PF08285.6 GAP90000.1 - 0.21 11.4 0.0 0.55 10.1 0.0 1.6 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Gal4_dimer PF03902.8 GAP90000.1 - 0.55 10.2 2.0 3 7.8 0.1 2.6 2 0 0 2 2 2 0 Gal4-like dimerisation domain Nol1_Nop2_Fmu PF01189.12 GAP90001.1 - 5.3e-20 71.9 0.0 7.8e-13 48.4 0.0 2.4 1 1 1 2 2 2 2 NOL1/NOP2/sun family DUF1996 PF09362.5 GAP90002.1 - 1.6e-64 217.7 0.5 2.4e-64 217.2 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Herpes_TAF50 PF03326.8 GAP90002.1 - 5.7 5.7 10.7 8.5 5.2 7.4 1.2 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Gtr1_RagA PF04670.7 GAP90003.1 - 6.9e-71 238.0 0.0 8.6e-71 237.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 GAP90003.1 - 0.0012 18.1 0.0 0.0024 17.1 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 GAP90003.1 - 0.0052 17.2 0.0 0.032 14.7 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein MIF PF01187.13 GAP90004.1 - 1.3e-09 38.1 0.0 2.2e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) ABM PF03992.11 GAP90007.1 - 7.7e-11 41.8 0.1 9.9e-11 41.5 0.1 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Abhydrolase_6 PF12697.2 GAP90008.1 - 6.3e-07 29.5 0.5 2.7e-06 27.4 0.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 GAP90008.1 - 0.0005 19.1 0.0 0.00078 18.5 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.15 GAP90008.1 - 0.0045 16.5 0.0 0.0079 15.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 GAP90008.1 - 0.019 14.2 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.8 GAP90008.1 - 0.15 11.6 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Ser_hydrolase PF06821.8 GAP90008.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase GST_N PF02798.15 GAP90009.1 - 2e-09 37.5 0.0 4e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAP90009.1 - 1.3e-06 28.2 0.0 1.9e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAP90009.1 - 6.1e-06 26.3 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAP90009.1 - 1.2e-05 25.7 0.0 2e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAP90009.1 - 7.9e-05 22.5 0.0 0.00022 21.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAP90009.1 - 0.0043 16.9 0.0 0.012 15.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1019 PF06254.6 GAP90010.1 - 0.071 13.2 0.0 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1019) SAP18 PF06487.7 GAP90012.1 - 4.5e-26 91.0 0.0 4.7e-26 90.9 0.0 1.0 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Prp18 PF02840.10 GAP90013.1 - 1.3e-50 170.9 2.0 1.3e-50 170.9 0.0 2.0 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 GAP90013.1 - 4.6e-10 38.5 6.8 4.6e-10 38.5 4.7 2.9 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Amidohydro_2 PF04909.9 GAP90013.1 - 0.24 10.9 6.1 0.18 11.3 3.0 1.6 2 0 0 2 2 2 0 Amidohydrolase RPN7 PF10602.4 GAP90014.1 - 6.8e-39 133.0 0.0 1e-38 132.4 0.0 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 GAP90014.1 - 1.4e-14 54.3 0.4 3.9e-14 52.8 0.3 1.8 2 0 0 2 2 2 1 PCI domain MFS_1 PF07690.11 GAP90015.1 - 4.6e-36 124.2 41.0 4.6e-36 124.2 28.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily PCMT PF01135.14 GAP90016.1 - 9.1e-41 139.7 0.0 5e-26 91.5 0.0 2.3 2 1 0 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 GAP90016.1 - 0.00046 20.7 0.0 0.00073 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP90016.1 - 0.002 17.7 0.0 0.0031 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF2235 PF09994.4 GAP90018.1 - 2.2e-28 99.4 0.1 2.4e-28 99.2 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_6 PF12697.2 GAP90019.1 - 0.036 13.9 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family SAB PF04382.8 GAP90019.1 - 0.036 13.7 0.1 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 SAB domain Peptidase_C14 PF00656.17 GAP90020.1 - 2.5e-07 30.6 0.0 4.4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Caspase domain DUF1912 PF08930.5 GAP90020.1 - 0.034 14.2 0.1 0.087 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) MMR_HSR1 PF01926.18 GAP90021.1 - 6.6e-08 32.5 1.6 7.5e-08 32.3 0.3 1.7 2 0 0 2 2 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 GAP90021.1 - 1.6e-06 27.3 0.7 1.6e-06 27.3 0.5 1.7 2 0 0 2 2 2 1 AIG1 family G-alpha PF00503.15 GAP90021.1 - 1.5e-05 23.9 1.1 0.0015 17.2 0.0 2.4 2 1 0 2 2 2 1 G-protein alpha subunit ABC_tran PF00005.22 GAP90021.1 - 5.4e-05 23.5 0.8 0.0006 20.1 0.0 2.4 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 GAP90021.1 - 9.3e-05 21.6 0.1 0.00025 20.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 GAP90021.1 - 0.00016 21.0 0.3 0.00033 19.9 0.2 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 GAP90021.1 - 0.00053 19.8 10.2 0.18 11.6 0.3 3.9 2 2 1 3 3 3 2 Dynamin family Miro PF08477.8 GAP90021.1 - 0.0033 17.9 0.0 0.0093 16.4 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein FH2 PF02181.18 GAP90021.1 - 0.01 14.7 1.6 0.023 13.5 0.9 1.7 2 0 0 2 2 2 0 Formin Homology 2 Domain AAA_33 PF13671.1 GAP90021.1 - 0.025 14.4 1.1 0.085 12.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain PV-1 PF06637.6 GAP90021.1 - 0.05 12.1 6.3 0.077 11.5 4.4 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) AAA_16 PF13191.1 GAP90021.1 - 0.058 13.3 0.5 0.75 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Rabaptin PF03528.10 GAP90021.1 - 0.073 12.9 11.3 0.39 10.6 7.8 2.3 1 1 0 1 1 1 0 Rabaptin AAA_22 PF13401.1 GAP90021.1 - 0.094 12.8 1.9 0.49 10.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain Nup88 PF10168.4 GAP90021.1 - 0.1 10.4 2.5 0.15 9.8 1.7 1.2 1 0 0 1 1 1 0 Nuclear pore component Phage_GPO PF05929.6 GAP90021.1 - 0.12 11.5 2.6 0.2 10.8 1.8 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF745 PF05335.8 GAP90021.1 - 0.13 11.7 3.7 0.078 12.4 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Adeno_IVa2 PF02456.10 GAP90021.1 - 0.16 10.6 0.2 0.7 8.4 0.0 2.1 2 1 1 3 3 3 0 Adenovirus IVa2 protein Arch_ATPase PF01637.13 GAP90021.1 - 0.16 11.6 2.2 2.5 7.7 0.0 3.0 3 1 1 4 4 4 0 Archaeal ATPase AAA_13 PF13166.1 GAP90021.1 - 0.21 9.9 3.7 0.37 9.1 2.5 1.3 1 0 0 1 1 1 0 AAA domain Jnk-SapK_ap_N PF09744.4 GAP90021.1 - 0.32 10.9 12.5 0.62 10.0 7.7 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 AAA_17 PF13207.1 GAP90021.1 - 0.32 11.8 2.3 0.97 10.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain DUF1451 PF07295.6 GAP90021.1 - 0.34 10.6 3.5 0.62 9.8 1.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1451) FUSC-like PF12805.2 GAP90021.1 - 0.35 9.7 4.5 0.56 9.0 3.1 1.3 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS V_ATPase_I PF01496.14 GAP90021.1 - 0.54 8.0 2.3 0.78 7.5 1.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OmpH PF03938.9 GAP90021.1 - 0.59 10.0 7.3 1.2 9.0 5.1 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HALZ PF02183.13 GAP90021.1 - 0.72 9.6 13.9 0.13 12.0 0.9 3.1 2 1 1 3 3 3 0 Homeobox associated leucine zipper SSFA2_C PF14723.1 GAP90021.1 - 0.91 9.2 6.2 2.2 7.9 4.3 1.6 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus APG6 PF04111.7 GAP90021.1 - 0.92 8.4 9.1 1.7 7.6 6.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4404 PF14357.1 GAP90021.1 - 1.6 9.2 12.2 34 4.9 7.0 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) DivIVA PF05103.8 GAP90021.1 - 3.5 7.6 10.8 2.4 8.2 5.6 2.1 2 0 0 2 2 1 0 DivIVA protein NmrA PF05368.8 GAP90023.1 - 4.8e-26 91.4 0.0 7.5e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAP90023.1 - 6.4e-16 58.8 0.4 9.2e-16 58.3 0.3 1.2 1 0 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 GAP90023.1 - 0.025 14.9 0.2 0.084 13.3 0.0 2.0 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Serglycin PF04360.7 GAP90023.1 - 0.044 13.5 0.2 0.083 12.6 0.1 1.4 1 0 0 1 1 1 0 Serglycin TrkA_N PF02254.13 GAP90023.1 - 0.063 13.2 0.0 0.15 12.0 0.0 1.7 1 1 0 1 1 1 0 TrkA-N domain Glyco_transf_28 PF03033.15 GAP90023.1 - 0.095 12.4 0.2 0.24 11.1 0.1 1.7 1 1 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Methyltransf_2 PF00891.13 GAP90025.1 - 1.9e-33 115.6 0.1 4.4e-33 114.4 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase D123 PF07065.9 GAP90026.1 - 9.5e-85 284.2 0.0 1.7e-84 283.4 0.0 1.4 1 1 0 1 1 1 1 D123 cwf21 PF08312.7 GAP90027.1 - 4.4e-09 36.0 10.1 4.4e-09 36.0 7.0 1.9 2 1 0 2 2 2 1 cwf21 domain DUF1640 PF07798.6 GAP90028.1 - 8.4e-12 45.4 3.9 1.2e-11 44.9 2.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Baculo_PEP_C PF04513.7 GAP90028.1 - 0.92 9.3 8.2 0.18 11.6 2.2 2.0 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HET PF06985.6 GAP90029.1 - 7.8e-23 81.1 0.0 1.5e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4131 PF13567.1 GAP90030.1 - 0.005 16.2 3.8 0.26 10.6 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4131) Cytochrom_B561 PF03188.11 GAP90030.1 - 0.0083 15.9 6.6 0.0083 15.9 4.6 2.0 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 GAP90030.1 - 0.082 12.4 1.8 0.19 11.3 1.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) Nnf1 PF03980.9 GAP90031.1 - 3.4e-29 101.0 4.1 3.5e-29 100.9 0.0 2.4 2 0 0 2 2 2 1 Nnf1 ADIP PF11559.3 GAP90031.1 - 0.025 14.4 0.4 0.025 14.4 0.3 2.8 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Spore_coat_CotO PF14153.1 GAP90031.1 - 0.071 12.5 6.4 0.015 14.7 2.1 1.6 2 0 0 2 2 2 0 Spore coat protein CotO Mcm10 PF09332.6 GAP90031.1 - 0.31 10.3 12.3 0.025 13.9 5.5 1.3 2 0 0 2 2 2 0 Mcm10 replication factor TerB-C PF15615.1 GAP90031.1 - 0.39 10.9 9.1 1.7 8.8 2.2 2.2 2 0 0 2 2 2 0 TerB-C domain NTF2 PF02136.15 GAP90032.1 - 2e-22 79.7 0.9 3.1e-22 79.1 0.6 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 GAP90032.1 - 2.4e-05 23.8 0.1 4.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP90032.1 - 5e-05 23.1 0.0 9.7e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP90032.1 - 9e-05 22.2 0.1 0.00018 21.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RIP PF00161.14 GAP90032.1 - 0.014 14.5 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Ribosome inactivating protein RRM_3 PF08777.6 GAP90032.1 - 0.04 13.7 0.0 0.092 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif Syndecan PF01034.15 GAP90033.1 - 0.21 11.2 1.3 0.4 10.3 0.9 1.4 1 0 0 1 1 1 0 Syndecan domain Granulin PF00396.13 GAP90033.1 - 0.43 10.7 15.1 0.24 11.5 1.5 3.2 3 0 0 3 3 3 0 Granulin Cad PF03596.8 GAP90035.1 - 1.9e-25 89.6 11.4 3.3e-25 88.9 7.9 1.3 1 0 0 1 1 1 1 Cadmium resistance transporter CcmH PF03918.9 GAP90035.1 - 0.12 11.3 0.3 0.65 8.9 0.0 2.1 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Ran_BP1 PF00638.13 GAP90036.1 - 3e-42 143.5 0.5 5.7e-42 142.6 0.3 1.4 1 0 0 1 1 1 1 RanBP1 domain DUF1681 PF07933.9 GAP90036.1 - 0.034 13.6 0.3 0.073 12.6 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1681) DUF4211 PF13926.1 GAP90037.1 - 1.5e-36 125.0 0.0 6.8e-36 122.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) IGPS PF00218.16 GAP90038.1 - 3.2e-96 321.2 0.1 4.5e-96 320.8 0.0 1.2 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 GAP90038.1 - 2.2e-50 170.7 0.0 3.2e-49 167.0 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase class-I PRAI PF00697.17 GAP90038.1 - 4.4e-44 150.4 0.0 1.2e-43 148.9 0.0 1.7 2 0 0 2 2 2 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.8 GAP90038.1 - 0.00016 21.2 0.1 0.00055 19.4 0.1 1.8 1 1 0 1 1 1 1 Peptidase C26 NanE PF04131.9 GAP90038.1 - 0.073 12.0 0.1 0.65 8.9 0.0 2.1 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Nup188 PF10487.4 GAP90039.1 - 5.7e-34 117.2 0.1 4e-29 101.1 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 AAA PF00004.24 GAP90040.1 - 5.2e-18 65.5 0.0 9.3e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAP90040.1 - 0.00033 20.7 0.0 0.0011 19.0 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 GAP90040.1 - 0.00049 20.8 0.0 0.0017 19.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 GAP90040.1 - 0.00086 19.0 0.0 0.0026 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 GAP90040.1 - 0.0021 18.1 0.1 0.014 15.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAP90040.1 - 0.0031 17.2 0.1 0.0074 16.0 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 GAP90040.1 - 0.031 12.9 0.0 0.05 12.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus RuvB_N PF05496.7 GAP90040.1 - 0.047 12.7 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 GAP90040.1 - 0.094 12.5 0.0 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 GAP90040.1 - 0.14 12.4 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 GAP90040.1 - 0.17 11.2 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein zf-Tim10_DDP PF02953.10 GAP90041.1 - 1.1e-20 72.6 3.8 1.4e-20 72.3 2.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 GAP90041.1 - 0.0034 16.8 2.6 0.0071 15.8 1.8 1.6 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Baculo_gp41 PF04700.7 GAP90041.1 - 0.097 12.0 0.0 0.098 12.0 0.0 1.1 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region Peptidase_C12 PF01088.16 GAP90042.1 - 1.4e-56 191.0 0.0 1.6e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Ribosomal_L10 PF00466.15 GAP90043.1 - 0.0012 18.7 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 U1snRNP70_N PF12220.3 GAP90044.1 - 2.2e-30 104.8 0.7 5.2e-30 103.6 0.5 1.7 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 GAP90044.1 - 2.1e-16 59.3 0.1 1.2e-15 56.8 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP90044.1 - 9.4e-12 44.7 0.0 1.6e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP90044.1 - 3.6e-09 36.3 0.0 8.2e-09 35.1 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 GAP90045.1 - 2.6e-10 39.8 0.0 4.3e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP90045.1 - 0.0026 16.8 0.0 0.0042 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAP90045.1 - 0.0035 17.1 0.2 0.009 15.7 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 GAP90045.1 - 0.022 13.8 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family L51_S25_CI-B8 PF05047.11 GAP90046.1 - 4.9e-15 54.9 0.0 7.1e-15 54.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain TIM PF00121.13 GAP90047.1 - 1.7e-87 292.5 0.3 2e-87 292.3 0.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase BP28CT PF08146.7 GAP90048.1 - 5.2e-39 133.4 1.1 5.2e-39 133.4 0.8 2.4 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 GAP90048.1 - 3.7e-23 81.7 10.3 1e-22 80.3 0.1 5.3 5 1 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 GAP90048.1 - 8.3e-05 22.3 11.5 0.11 12.6 0.0 6.2 5 0 0 5 5 5 2 HEAT repeat Lipase_GDSL_2 PF13472.1 GAP90049.1 - 3.7e-17 63.0 0.0 4.6e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAP90049.1 - 1.2e-16 61.2 0.0 1.5e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 GAP90049.1 - 0.031 14.0 0.0 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family DUF919 PF06034.6 GAP90050.1 - 0.048 13.2 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) TMP-TENI PF02581.12 GAP90051.1 - 2.5e-58 196.1 3.3 3e-58 195.9 2.3 1.1 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI HK PF02110.10 GAP90051.1 - 6.2e-06 25.5 0.0 9.5e-06 24.9 0.0 1.5 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family QRPTase_C PF01729.14 GAP90051.1 - 0.04 13.4 0.0 0.077 12.5 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain CutC PF03932.9 GAP90051.1 - 0.14 11.4 2.4 0.18 11.0 0.8 1.8 1 1 1 2 2 2 0 CutC family Isochorismatase PF00857.15 GAP90052.1 - 7.3e-24 84.6 0.0 1.9e-23 83.2 0.0 1.7 1 1 0 1 1 1 1 Isochorismatase family Glyco_trans_4_4 PF13579.1 GAP90052.1 - 0.00021 21.4 1.3 0.2 11.7 0.1 2.2 2 0 0 2 2 2 2 Glycosyl transferase 4-like domain Glyco_hydro_30 PF02055.11 GAP90053.1 - 2.5e-12 45.7 0.5 2.6e-06 25.9 0.2 2.4 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 GAP90053.1 - 3.4e-09 36.1 0.0 5.5e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Aminotran_1_2 PF00155.16 GAP90054.1 - 3.1e-83 279.7 0.0 3.8e-83 279.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 GAP90054.1 - 1.8e-05 23.6 0.0 8.1e-05 21.5 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 GAP90054.1 - 2.2e-05 22.9 0.0 3.4e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 GAP90054.1 - 0.0027 16.8 0.1 0.006 15.6 0.1 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Acyltransferase PF01553.16 GAP90056.1 - 2.8e-34 117.3 0.0 4.3e-34 116.7 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF4281 PF14108.1 GAP90056.1 - 0.011 15.7 2.6 0.024 14.7 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4281) HEAT PF02985.17 GAP90058.1 - 5e-05 23.0 2.5 0.14 12.3 0.0 5.7 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.1 GAP90058.1 - 0.00033 20.8 5.1 0.0086 16.3 0.2 5.1 6 1 1 7 7 7 2 HEAT repeats HEAT_EZ PF13513.1 GAP90058.1 - 0.067 13.6 3.0 1.5 9.4 0.0 4.4 4 0 0 4 4 4 0 HEAT-like repeat CENP-M PF11111.3 GAP90058.1 - 0.079 12.1 0.2 2.6 7.2 0.0 2.6 3 0 0 3 3 3 0 Centromere protein M (CENP-M) mRNA_cap_enzyme PF01331.14 GAP90059.1 - 4.9e-52 176.4 0.2 6.3e-52 176.0 0.1 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 GAP90059.1 - 1e-19 70.8 0.0 1.9e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 GAP90059.1 - 7.9e-07 28.6 0.2 3.4e-05 23.2 0.1 2.6 2 1 0 2 2 2 1 ATP dependent DNA ligase domain Glyco_hydro_3 PF00933.16 GAP90060.1 - 2.3e-92 309.1 0.0 3.3e-92 308.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAP90060.1 - 3.4e-57 193.6 0.5 1.6e-56 191.3 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAP90060.1 - 2.3e-14 53.0 0.0 4.2e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF2528 PF10800.3 GAP90060.1 - 0.063 13.6 0.1 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2528) Vac_Fusion PF02346.11 GAP90061.1 - 0.014 14.7 0.7 1 8.8 0.0 3.7 4 0 0 4 4 4 0 Chordopoxvirus fusion protein PAR1 PF06521.6 GAP90061.1 - 0.072 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 PAR1 protein Baculo_PEP_C PF04513.7 GAP90061.1 - 0.12 12.1 0.2 20 5.0 0.0 3.3 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.7 GAP90061.1 - 5.1 7.5 13.0 3 8.2 0.2 4.7 4 1 1 5 5 5 0 SlyX FAM180 PF15173.1 GAP90062.1 - 0.07 12.8 0.1 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 FAM180 family NIR_SIR_ferr PF03460.12 GAP90062.1 - 0.1 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain SKG6 PF08693.5 GAP90063.1 - 0.0029 16.8 0.3 0.007 15.6 0.2 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 GAP90063.1 - 0.021 13.0 0.1 0.035 12.3 0.1 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SSP160 PF06933.6 GAP90063.1 - 0.023 12.6 5.6 0.034 12.1 3.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sensor PF13796.1 GAP90063.1 - 0.064 12.8 8.8 0.18 11.4 5.0 2.2 1 1 1 2 2 2 0 Putative sensor RNA_pol_I_A49 PF06870.7 GAP90065.1 - 7.3e-74 248.6 0.1 8.7e-74 248.3 0.0 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Tad PF13400.1 GAP90065.1 - 0.3 11.1 2.4 0.64 10.1 1.7 1.5 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Abhydrolase_6 PF12697.2 GAP90066.1 - 7.6e-16 58.6 10.4 9.7e-16 58.3 7.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP90066.1 - 1e-07 31.7 1.7 1.5e-07 31.2 1.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP90066.1 - 1.1e-07 31.6 0.2 1.3e-07 31.4 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 GAP90066.1 - 0.018 14.4 0.2 0.035 13.5 0.1 1.6 1 1 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.3 GAP90066.1 - 0.04 13.7 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_S9 PF00326.16 GAP90066.1 - 0.068 12.3 0.1 0.088 12.0 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Fungal_trans PF04082.13 GAP90067.1 - 1.5e-08 33.8 0.0 2.8e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP90067.1 - 0.007 16.2 8.0 0.02 14.8 5.5 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1512 PF07431.7 GAP90068.1 - 0.053 12.2 0.7 0.082 11.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) AMP-binding PF00501.23 GAP90069.1 - 0 1055.7 1.4 2.4e-82 276.5 0.0 5.0 5 0 0 5 5 5 4 AMP-binding enzyme Condensation PF00668.15 GAP90069.1 - 9.3e-150 497.5 0.0 6.9e-40 136.7 0.0 6.1 5 1 0 5 5 5 4 Condensation domain PP-binding PF00550.20 GAP90069.1 - 1.7e-36 124.2 5.1 9.9e-09 35.3 0.7 5.1 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAP90069.1 - 1.3e-23 83.7 0.0 2.6e-06 28.2 0.0 5.1 4 0 0 4 4 4 4 AMP-binding enzyme C-terminal domain GH3 PF03321.8 GAP90069.1 - 1.2 7.5 0.0 1.3e+02 0.8 0.0 3.3 4 0 0 4 4 4 0 GH3 auxin-responsive promoter Amidinotransf PF02274.12 GAP90070.1 - 2.3e-08 33.4 0.0 2.2e-06 26.9 0.0 2.6 1 1 0 1 1 1 1 Amidinotransferase Cys_Met_Meta_PP PF01053.15 GAP90071.1 - 9.4e-32 109.7 0.0 1.2e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 GAP90071.1 - 0.00065 18.7 0.0 0.00099 18.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II YqcI_YcgG PF08892.6 GAP90072.1 - 1.3e-33 116.4 0.0 2.1e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 YqcI/YcgG family PhyH PF05721.8 GAP90073.1 - 9.8e-15 55.1 0.1 2.3e-14 53.9 0.1 1.6 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Sulfotransfer_3 PF13469.1 GAP90073.1 - 2.5e-05 25.2 3.3 3.6e-05 24.7 1.4 1.9 1 1 0 1 1 1 1 Sulfotransferase family AraC_binding PF02311.14 GAP90073.1 - 0.0073 16.0 0.1 3.5 7.3 0.0 2.8 2 0 0 2 2 2 2 AraC-like ligand binding domain Arylsulfotran_2 PF14269.1 GAP90074.1 - 3.1e-49 167.7 0.1 4e-49 167.3 0.1 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 GAP90074.1 - 2e-16 59.5 0.8 5.3e-16 58.1 0.3 1.8 2 1 0 2 2 2 1 Arylsulfotransferase (ASST) Glu_synthase PF01645.12 GAP90075.1 - 1.4e-159 530.8 0.0 2.4e-159 530.1 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 GAP90075.1 - 1.9e-142 474.2 0.0 2.6e-142 473.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 GAP90075.1 - 1.6e-115 385.3 0.0 2.8e-115 384.5 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 GAP90075.1 - 8.8e-65 217.4 4.7 1.7e-64 216.5 3.2 1.5 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 GAP90075.1 - 1.1e-22 79.7 0.1 2.6e-22 78.5 0.1 1.7 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 GAP90075.1 - 2.8e-16 60.0 0.0 1.1e-15 58.0 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP90075.1 - 1.5e-10 41.5 0.2 0.00045 20.3 0.0 2.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP90075.1 - 4.1e-09 36.3 0.0 1.5e-08 34.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAP90075.1 - 2e-08 34.4 0.1 1e-05 25.8 0.1 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 GAP90075.1 - 1.1e-06 28.0 0.0 2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 GAP90075.1 - 1.7e-05 23.9 0.4 0.0001 21.3 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAP90075.1 - 3.8e-05 22.3 0.1 3.8e-05 22.3 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 GAP90075.1 - 0.00011 21.3 0.1 0.00038 19.6 0.1 1.9 1 0 0 1 1 1 1 Thi4 family FMO-like PF00743.14 GAP90075.1 - 0.00029 19.2 0.4 0.055 11.6 0.0 2.8 2 1 1 3 3 3 1 Flavin-binding monooxygenase-like FAD_binding_2 PF00890.19 GAP90075.1 - 0.00037 19.4 0.1 0.0019 17.0 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 GAP90075.1 - 0.001 19.2 1.0 1.1 9.5 0.1 2.9 2 0 0 2 2 2 2 Putative NAD(P)-binding FAD_oxidored PF12831.2 GAP90075.1 - 0.0037 16.4 0.0 0.0075 15.3 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 GAP90075.1 - 0.0074 16.0 0.0 0.042 13.5 0.0 2.2 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.16 GAP90075.1 - 0.014 15.0 0.3 0.32 10.5 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 GAP90075.1 - 0.014 14.4 0.0 0.031 13.3 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain DJ-1_PfpI PF01965.19 GAP90075.1 - 0.026 14.0 0.4 6.4 6.2 0.0 2.5 1 1 1 2 2 2 0 DJ-1/PfpI family NAD_binding_9 PF13454.1 GAP90075.1 - 0.048 13.4 0.0 0.21 11.3 0.0 2.2 1 0 0 1 1 1 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 GAP90075.1 - 0.44 9.4 0.0 22 3.7 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) MADF_DNA_bdg PF10545.4 GAP90075.1 - 0.49 10.6 3.3 0.33 11.1 0.6 1.9 2 0 0 2 2 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Apc15p PF05841.6 GAP90076.1 - 2.3e-22 80.0 2.2 2.3e-22 80.0 1.5 3.1 3 1 0 3 3 3 1 Apc15p protein TFIIA PF03153.8 GAP90076.1 - 0.0013 18.6 32.2 0.0013 18.6 22.3 2.9 1 1 1 2 2 2 1 Transcription factor IIA, alpha/beta subunit SNARE PF05739.14 GAP90077.1 - 8.3e-10 38.2 1.7 1.1e-09 37.8 1.2 1.2 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 GAP90077.1 - 0.016 14.6 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 CHZ PF09649.5 GAP90078.1 - 2.9e-16 58.3 2.2 2.9e-16 58.3 1.5 2.4 3 0 0 3 3 3 1 Histone chaperone domain CHZ UPF0370 PF13980.1 GAP90079.1 - 0.061 13.1 0.6 0.11 12.3 0.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) Cyclin PF08613.6 GAP90080.1 - 3.1e-28 99.0 0.0 4.6e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 GAP90080.1 - 0.00078 19.0 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Arm PF00514.18 GAP90081.1 - 3.5e-16 58.3 9.5 0.00017 21.3 0.1 8.0 8 0 0 8 8 8 4 Armadillo/beta-catenin-like repeat HEAT PF02985.17 GAP90081.1 - 3e-06 26.8 16.3 1.8 8.8 0.1 8.2 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 GAP90081.1 - 9.8e-05 22.5 8.0 1.1 9.5 0.0 5.9 5 1 1 6 6 6 3 HEAT repeats Ric8 PF10165.4 GAP90081.1 - 0.0027 16.5 1.1 0.38 9.5 0.7 3.6 3 1 0 3 3 3 1 Guanine nucleotide exchange factor synembryn DDE_Tnp_2 PF04693.7 GAP90081.1 - 0.014 14.3 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal putative transposase ISC1217 V-ATPase_H_C PF11698.3 GAP90081.1 - 0.049 13.5 4.9 0.052 13.4 0.1 3.2 5 0 0 5 5 5 0 V-ATPase subunit H HEAT_EZ PF13513.1 GAP90081.1 - 1.4 9.4 12.8 21 5.7 0.1 7.2 9 0 0 9 9 9 0 HEAT-like repeat Ribosomal_60s PF00428.14 GAP90082.1 - 0.046 14.1 0.1 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Bac_rhodopsin PF01036.13 GAP90084.1 - 2.5e-25 89.1 17.5 2.9e-25 88.8 12.1 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Velvet PF11754.3 GAP90087.1 - 4.1e-60 202.8 0.0 8.6e-60 201.8 0.0 1.5 2 0 0 2 2 2 1 Velvet factor Ank PF00023.25 GAP90089.1 - 3.3e-16 58.1 0.0 3e-08 33.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 GAP90089.1 - 1.5e-15 57.2 0.0 2.8e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAP90089.1 - 2.3e-15 56.2 0.0 1e-11 44.6 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) TIG PF01833.19 GAP90089.1 - 1.4e-14 53.8 0.4 4.1e-14 52.3 0.3 1.8 1 0 0 1 1 1 1 IPT/TIG domain Ank_3 PF13606.1 GAP90089.1 - 1.4e-11 43.4 0.0 0.00032 20.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 GAP90089.1 - 1.6e-08 34.7 0.0 5.1e-07 30.0 0.0 2.9 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Na_H_Exchanger PF00999.16 GAP90090.1 - 1.7e-36 125.6 13.5 4.1e-36 124.3 9.4 1.5 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4044 PF13253.1 GAP90090.1 - 2.4 7.3 4.6 8.7 5.5 3.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Cauli_VI PF01693.11 GAP90091.1 - 1.3e-30 105.1 5.6 2.3e-16 59.5 0.2 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 GAP90091.1 - 2.1e-25 89.5 0.0 3.8e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 RNase H Mucin PF01456.12 GAP90091.1 - 0.84 9.4 6.1 1.8 8.3 4.2 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein dCMP_cyt_deam_1 PF00383.17 GAP90092.1 - 2e-09 36.9 0.1 1.7e-08 34.0 0.0 2.2 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 GAP90092.1 - 0.05 13.4 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase 6PF2K PF01591.13 GAP90093.1 - 1.5e-64 217.1 0.0 4.9e-44 150.0 0.0 2.3 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 GAP90093.1 - 1.4e-22 80.4 0.2 5.8e-22 78.4 0.1 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 GAP90093.1 - 1.7e-05 24.7 0.0 6.9e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 GAP90093.1 - 0.019 14.1 0.0 0.043 13.0 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_17 PF13207.1 GAP90093.1 - 0.036 14.8 0.0 0.23 12.2 0.0 2.3 2 1 1 3 3 3 0 AAA domain Transposase_22 PF02994.9 GAP90093.1 - 0.16 10.4 0.1 0.29 9.5 0.1 1.3 1 0 0 1 1 1 0 L1 transposable element RHD3 PF05879.7 GAP90094.1 - 0 1047.5 0.0 0 1047.2 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 GAP90094.1 - 6.9e-09 35.1 0.3 1.2e-08 34.3 0.2 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 GAP90094.1 - 8.9e-07 28.8 0.0 1.6e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 GAP90094.1 - 1.7e-05 24.7 0.1 3.5e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAP90094.1 - 0.00024 21.5 0.1 0.00046 20.6 0.1 1.4 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 GAP90094.1 - 0.00038 20.4 0.2 0.0028 17.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Cys_Met_Meta_PP PF01053.15 GAP90094.1 - 0.053 11.7 0.1 0.083 11.1 0.1 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Septin PF00735.13 GAP90094.1 - 0.061 12.3 0.2 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 Septin RNase_HII PF01351.13 GAP90095.1 - 1.4e-42 145.5 0.0 7.7e-38 130.1 0.0 2.1 2 0 0 2 2 2 2 Ribonuclease HII Ribosomal_60s PF00428.14 GAP90095.1 - 0.0052 17.1 10.4 0.015 15.7 7.2 1.7 1 0 0 1 1 1 1 60s Acidic ribosomal protein Mif2_N PF15624.1 GAP90096.1 - 3.3e-30 105.4 1.7 3.3e-30 105.4 1.2 4.4 2 1 2 5 5 5 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.3 GAP90096.1 - 1.5e-15 56.9 0.1 5.3e-12 45.5 0.0 2.4 1 1 1 2 2 2 2 Mif2/CENP-C like RNA12 PF10443.4 GAP90097.1 - 3.6e-158 526.6 0.6 3e-157 523.5 0.2 1.9 2 0 0 2 2 2 1 RNA12 protein RRM_1 PF00076.17 GAP90097.1 - 1.4e-05 24.6 0.0 0.00013 21.5 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arch_ATPase PF01637.13 GAP90097.1 - 2.5e-05 24.0 0.1 0.0001 22.1 0.1 1.9 1 1 0 1 1 1 1 Archaeal ATPase DUF2487 PF10673.4 GAP90097.1 - 0.0099 15.6 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) AAA_14 PF13173.1 GAP90097.1 - 0.01 15.7 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain RRM_6 PF14259.1 GAP90097.1 - 0.024 14.6 0.0 0.24 11.4 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP90097.1 - 0.15 11.9 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3128 PF11326.3 GAP90098.1 - 5.4e-25 87.3 0.2 1e-24 86.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) HSP70 PF00012.15 GAP90099.1 - 1.7e-267 888.2 4.9 2e-267 888.0 3.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAP90099.1 - 2e-17 62.8 0.2 4.6e-16 58.3 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 GAP90099.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 GAP90099.1 - 0.014 14.5 0.1 0.039 13.0 0.0 1.7 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Actin PF00022.14 GAP90099.1 - 0.028 12.8 0.0 0.44 8.9 0.0 2.2 1 1 0 1 1 1 0 Actin StbA PF06406.6 GAP90099.1 - 0.05 12.5 0.0 0.096 11.6 0.0 1.4 1 0 0 1 1 1 0 StbA protein FtsA PF14450.1 GAP90099.1 - 0.24 11.2 2.6 8.5 6.2 1.8 3.1 1 1 0 1 1 1 0 Cell division protein FtsA OPT PF03169.10 GAP90100.1 - 1.4e-145 486.2 31.0 2e-145 485.7 21.5 1.2 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DLH PF01738.13 GAP90100.1 - 5.1e-26 91.3 0.0 7.8e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.6 GAP90100.1 - 0.00087 19.0 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 GAP90100.1 - 0.0079 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) HD PF01966.17 GAP90101.1 - 3.4e-06 27.0 0.0 5.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 HD domain Mucin PF01456.12 GAP90102.1 - 0.0038 17.0 10.9 0.0061 16.3 7.6 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein PAN_1 PF00024.21 GAP90102.1 - 0.85 9.4 6.2 0.071 12.8 0.9 1.7 2 0 0 2 2 2 0 PAN domain Rav1p_C PF12234.3 GAP90103.1 - 1.8e-259 862.1 0.1 3e-259 861.5 0.0 1.4 2 0 0 2 2 2 1 RAVE protein 1 C terminal WD40 PF00400.27 GAP90103.1 - 0.0002 21.1 1.4 1.5 8.7 0.0 5.4 5 0 0 5 5 5 1 WD domain, G-beta repeat Peptidase_S39 PF02122.10 GAP90103.1 - 0.089 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase S39 Sfi1 PF08457.5 GAP90104.1 - 1.6e-19 69.7 70.0 9.4e-12 44.1 27.2 4.2 3 2 2 5 5 5 3 Sfi1 spindle body protein tRNA-synt_1 PF00133.17 GAP90105.1 - 4.7e-220 731.6 0.2 1.1e-219 730.4 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 GAP90105.1 - 7.1e-25 87.5 0.0 2.4e-24 85.8 0.0 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 GAP90105.1 - 1.7e-17 63.1 0.2 2.5e-07 29.7 0.1 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 GAP90105.1 - 0.062 12.4 0.0 0.15 11.1 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Mo25 PF08569.6 GAP90108.1 - 5.1e-115 384.0 0.0 5.7e-115 383.9 0.0 1.0 1 0 0 1 1 1 1 Mo25-like adh_short PF00106.20 GAP90109.1 - 2.9e-23 82.6 0.3 4.8e-23 81.8 0.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP90109.1 - 7e-12 45.6 0.0 9.2e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP90109.1 - 1.4e-07 31.3 0.9 2.9e-07 30.3 0.2 1.9 2 1 0 2 2 2 1 KR domain SWIB PF02201.13 GAP90110.1 - 3e-12 46.0 0.0 8.7e-12 44.5 0.0 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain PAT1 PF09770.4 GAP90110.1 - 0.076 11.2 33.4 0.14 10.3 23.1 1.5 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Band_3_cyto PF07565.8 GAP90110.1 - 0.091 12.2 3.1 0.17 11.3 2.2 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4407 PF14362.1 GAP90110.1 - 1.4 7.8 5.5 2.1 7.2 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Suf PF05843.9 GAP90110.1 - 7 6.2 17.3 2.2 7.9 9.2 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Pex16 PF08610.5 GAP90110.1 - 8.1 5.3 13.1 13 4.6 9.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Pkinase PF00069.20 GAP90111.1 - 1e-69 234.5 0.0 2.4e-69 233.3 0.0 1.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP90111.1 - 4e-36 124.4 0.0 4.6e-35 120.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP90111.1 - 8.9e-05 21.5 0.4 0.0049 15.8 0.0 2.8 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 GAP90111.1 - 0.00035 19.6 0.0 0.00058 18.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAP90111.1 - 0.0023 17.6 0.1 0.012 15.3 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family APC_CDC26 PF10471.4 GAP90112.1 - 9.9e-07 29.4 0.2 9.9e-07 29.4 0.1 2.2 2 1 0 2 2 2 1 Anaphase-promoting complex APC subunit 1 Trypsin PF00089.21 GAP90114.1 - 0.088 12.3 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Trypsin XPG_I PF00867.13 GAP90115.1 - 6.1e-25 87.1 0.0 1.3e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 GAP90115.1 - 6e-08 32.8 0.0 1.2e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain Actin PF00022.14 GAP90116.1 - 9.4e-23 80.2 0.0 8.6e-22 77.1 0.0 2.1 1 1 0 1 1 1 1 Actin DUF3630 PF12305.3 GAP90116.1 - 0.015 15.1 0.1 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3630) MreB_Mbl PF06723.8 GAP90116.1 - 0.22 10.0 0.0 1.2 7.6 0.0 1.8 2 0 0 2 2 2 0 MreB/Mbl protein HET PF06985.6 GAP90117.1 - 5.4e-36 123.8 5.6 1.7e-35 122.2 3.9 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) tRNA-synt_2b PF00587.20 GAP90117.1 - 1.8e-20 73.2 0.0 1.3e-19 70.4 0.0 2.4 3 0 0 3 3 3 1 tRNA synthetase class II core domain (G, H, P, S and T) TPR_12 PF13424.1 GAP90117.1 - 1.5e-11 44.0 2.0 7.6e-08 32.1 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat Seryl_tRNA_N PF02403.17 GAP90117.1 - 1.5e-11 44.2 6.6 2.1e-06 27.7 0.1 2.8 3 0 0 3 3 3 2 Seryl-tRNA synthetase N-terminal domain TPR_10 PF13374.1 GAP90117.1 - 7.2e-11 41.6 1.7 6.1e-07 29.1 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat Ank_2 PF12796.2 GAP90117.1 - 1e-05 25.7 0.2 0.31 11.3 0.0 3.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) DUF3782 PF12644.2 GAP90118.1 - 0.52 10.1 21.0 1.4e+03 -0.9 0.0 7.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3782) Mito_carr PF00153.22 GAP90119.1 - 1.2e-28 98.5 0.5 1.1e-14 53.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_Rpc82 PF05645.8 GAP90120.1 - 3.7e-38 131.5 0.1 2.6e-37 128.7 0.0 2.4 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 GAP90120.1 - 2.7e-19 68.8 0.8 1.2e-17 63.5 0.1 3.3 4 0 0 4 4 4 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 GAP90120.1 - 1.9e-06 27.3 0.7 0.0014 18.0 0.0 3.1 3 0 0 3 3 3 2 TFIIE alpha subunit ATP-synt_Eps PF04627.8 GAP90121.1 - 2.6e-21 74.8 0.6 2.6e-21 74.8 0.4 2.3 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain Peptidase_M16 PF00675.15 GAP90121.1 - 2.9e-17 62.7 0.1 6.2e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 GAP90121.1 - 1.4e-15 57.4 0.1 2.1e-14 53.5 0.0 2.5 3 0 0 3 3 3 1 Peptidase M16 inactive domain Mak10 PF04112.8 GAP90122.1 - 4.7e-48 162.5 0.0 7.7e-48 161.8 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Mito_carr PF00153.22 GAP90123.1 - 2e-50 168.4 4.3 8.9e-16 57.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Abp2 PF09441.5 GAP90124.1 - 2.2e-87 291.4 0.0 7.9e-87 289.6 0.0 1.8 2 0 0 2 2 2 1 ARS binding protein 2 Sugar_tr PF00083.19 GAP90125.1 - 3.1e-88 296.3 23.3 3.9e-88 296.0 16.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP90125.1 - 3.7e-14 52.2 50.6 6.8e-08 31.6 12.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PFL PF02901.10 GAP90126.1 - 0.096 11.0 0.0 0.13 10.6 0.0 1.2 1 0 0 1 1 1 0 Pyruvate formate lyase RasGAP PF00616.14 GAP90127.1 - 1.9e-44 151.6 0.2 3.8e-44 150.7 0.2 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 GAP90127.1 - 0.00082 19.2 0.1 0.0026 17.6 0.0 1.9 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain XRN_N PF03159.13 GAP90128.1 - 1.2e-107 358.7 0.0 2.4e-107 357.7 0.0 1.5 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus DUF690 PF05108.8 GAP90128.1 - 0.19 10.0 0.0 0.28 9.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF690) Uso1_p115_head PF04869.9 GAP90129.1 - 4.2e-107 357.5 0.0 7.6e-107 356.6 0.0 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region PrmA PF06325.8 GAP90129.1 - 2.7e-08 33.3 0.1 2.7e-08 33.3 0.1 2.0 2 0 0 2 2 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 GAP90129.1 - 3.9e-08 33.8 0.1 3.9e-08 33.8 0.0 3.1 2 1 1 3 3 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP90129.1 - 6.3e-08 32.6 0.0 2.9e-07 30.5 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP90129.1 - 5.9e-07 29.1 0.1 2.2e-06 27.3 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP90129.1 - 2.4e-06 27.9 1.3 7.2e-06 26.4 0.0 2.6 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP90129.1 - 3.6e-06 26.8 0.0 1.5e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAP90129.1 - 9.8e-05 21.7 0.0 0.00027 20.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase small domain Uso1_p115_C PF04871.8 GAP90129.1 - 0.00019 21.4 41.4 0.00019 21.4 28.7 4.4 3 1 2 5 5 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region CMAS PF02353.15 GAP90129.1 - 0.00095 18.3 0.0 0.002 17.2 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 GAP90129.1 - 0.0023 18.2 0.1 0.018 15.4 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 GAP90129.1 - 0.0076 14.9 0.0 0.023 13.3 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.4 GAP90129.1 - 0.017 14.5 0.0 0.038 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_12 PF08242.7 GAP90129.1 - 0.031 14.7 3.4 0.042 14.3 0.0 2.9 3 0 0 3 3 3 0 Methyltransferase domain PCMT PF01135.14 GAP90129.1 - 0.031 13.7 0.0 0.068 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Arm PF00514.18 GAP90129.1 - 0.1 12.4 0.4 11 5.9 0.0 3.7 4 0 0 4 4 3 0 Armadillo/beta-catenin-like repeat Methyltransf_24 PF13578.1 GAP90129.1 - 3.6 8.4 7.0 2.5 8.9 0.0 3.2 2 1 0 2 2 2 0 Methyltransferase domain DUF3818 PF12825.2 GAP90129.1 - 4.4 5.8 9.1 9.3 4.8 6.3 1.5 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) MS_channel PF00924.13 GAP90130.1 - 5.4e-18 65.0 2.0 8.7e-18 64.3 1.4 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 GAP90130.1 - 0.00094 18.3 0.3 0.0024 17.0 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 GAP90130.1 - 0.001 18.3 0.1 0.0021 17.3 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 GAP90130.1 - 0.0049 16.6 0.1 0.013 15.2 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 GAP90130.1 - 0.031 14.4 0.0 0.074 13.2 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair HhH-GPD PF00730.20 GAP90131.1 - 4.6e-18 65.4 0.0 8.6e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 GAP90131.1 - 2.4e-15 55.9 0.0 8.2e-15 54.2 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain HHH PF00633.18 GAP90131.1 - 0.0009 18.8 0.2 0.0024 17.4 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 GAP90131.1 - 0.13 12.4 0.0 10 6.3 0.0 2.8 3 0 0 3 3 3 0 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.4 GAP90131.1 - 2.5 8.4 9.4 6.3 7.1 6.5 1.7 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III PNGaseA PF12222.3 GAP90132.1 - 4.5e-107 358.5 0.2 6.1e-107 358.1 0.1 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A HAD_2 PF13419.1 GAP90134.1 - 3.8e-13 50.0 0.0 9e-13 48.8 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAP90134.1 - 1.4e-08 35.4 0.0 6.9e-08 33.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAP90134.1 - 2.2e-07 30.4 0.1 4.7e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like Glyco_hydro_26 PF02156.10 GAP90135.1 - 1.6e-92 310.3 2.9 2e-92 310.0 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 p450 PF00067.17 GAP90136.1 - 1.1e-53 182.4 0.0 1.3e-53 182.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF829 PF05705.9 GAP90137.1 - 2.4e-46 158.3 0.8 3.1e-46 158.0 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 GAP90137.1 - 0.089 12.6 0.0 0.16 11.8 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family 6PF2K PF01591.13 GAP90138.1 - 1.7e-77 259.4 0.0 2.3e-77 259.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 GAP90138.1 - 5.1e-34 117.6 0.1 1.3e-33 116.3 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 GAP90138.1 - 3e-10 40.1 0.0 5.1e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 GAP90138.1 - 0.00057 19.1 0.0 0.00089 18.5 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 GAP90138.1 - 0.0066 17.2 0.1 0.094 13.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain His_Phos_2 PF00328.17 GAP90138.1 - 0.041 13.2 0.0 0.11 11.8 0.0 1.6 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) HET PF06985.6 GAP90139.1 - 6.7e-20 71.6 0.0 1.3e-19 70.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.14 GAP90141.1 - 3.5e-76 256.5 0.0 4.4e-76 256.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 GAP90141.1 - 5.6e-39 133.4 0.0 9.5e-39 132.7 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.22 GAP90141.1 - 1.9e-05 24.9 0.0 0.00063 20.0 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP90141.1 - 0.0016 18.4 0.0 0.0058 16.6 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain XdhC_C PF13478.1 GAP90141.1 - 0.0028 17.9 0.0 0.0069 16.6 0.0 1.7 1 0 0 1 1 1 1 XdhC Rossmann domain DAO PF01266.19 GAP90141.1 - 0.0077 15.1 0.1 0.27 10.1 0.0 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAP90141.1 - 0.018 14.9 0.0 0.042 13.7 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAP90141.1 - 0.02 13.8 0.0 0.044 12.6 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.9 GAP90141.1 - 0.029 12.8 0.0 0.07 11.5 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 GAP90141.1 - 0.1 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.9 GAP90141.1 - 0.12 11.7 0.1 0.33 10.2 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF4185 PF13810.1 GAP90142.1 - 3.2e-08 32.8 1.9 4e-08 32.5 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) Peptidase_C48 PF02902.14 GAP90143.1 - 4.2e-15 55.9 1.0 7.8e-15 55.0 0.7 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain zf-RING_2 PF13639.1 GAP90144.1 - 4.2e-06 26.4 8.1 7.4e-06 25.6 5.6 1.4 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAP90144.1 - 7.6e-06 25.9 1.1 9.5e-06 25.6 0.8 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 GAP90144.1 - 7.9e-05 22.5 6.2 0.00019 21.3 4.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAP90144.1 - 0.00015 21.3 5.2 0.00022 20.8 3.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 GAP90144.1 - 0.00046 19.7 5.2 0.00064 19.3 3.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAP90144.1 - 0.0005 19.6 5.1 0.001 18.7 3.5 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF983 PF06170.7 GAP90144.1 - 0.0026 17.8 2.7 0.025 14.7 0.3 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF983) zf-Nse PF11789.3 GAP90144.1 - 0.023 14.2 0.7 0.03 13.8 0.5 1.1 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 GAP90144.1 - 0.15 11.9 2.7 0.21 11.4 1.9 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger HypA PF01155.14 GAP90144.1 - 0.17 11.5 0.5 0.71 9.5 0.4 1.8 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-RING_UBOX PF13445.1 GAP90144.1 - 0.33 10.6 3.9 0.16 11.7 1.0 1.8 1 1 0 1 1 1 0 RING-type zinc-finger Rad50_zn_hook PF04423.9 GAP90144.1 - 0.37 10.2 2.2 0.55 9.7 0.2 2.0 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C3HC4_4 PF15227.1 GAP90144.1 - 0.93 9.4 4.6 0.38 10.6 1.2 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF4215 PF13948.1 GAP90144.1 - 1.7 8.9 5.5 0.66 10.2 1.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4215) zf-RING-like PF08746.6 GAP90144.1 - 2.6 8.1 7.4 20 5.2 5.2 2.1 1 1 0 1 1 1 0 RING-like domain Mito_carr PF00153.22 GAP90145.1 - 2.3e-67 222.7 6.7 9e-26 89.4 0.1 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 GAP90145.1 - 5.5e-24 84.0 3.8 1.4e-13 50.7 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 GAP90145.1 - 9.4e-21 71.4 3.9 2e-05 23.5 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 GAP90145.1 - 9.5e-20 68.6 5.9 5.7e-06 25.7 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 GAP90145.1 - 4.4e-17 60.5 5.3 6.1e-05 22.1 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 GAP90145.1 - 2.8e-13 49.2 1.3 3.4e-06 26.5 0.0 3.2 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 GAP90145.1 - 4.1e-09 36.4 0.5 0.00035 20.5 0.0 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 GAP90145.1 - 0.0073 16.0 2.3 1.3 8.7 0.0 3.2 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand Pilus_CpaD PF09476.5 GAP90145.1 - 0.06 12.8 0.0 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) EF-hand_10 PF14788.1 GAP90145.1 - 0.32 10.6 1.6 1.2 8.8 0.2 2.5 2 1 1 3 3 3 0 EF hand Cyclin_N PF00134.18 GAP90146.1 - 2.4e-12 46.5 0.2 2.4e-12 46.5 0.1 2.5 3 0 0 3 3 3 1 Cyclin, N-terminal domain TFIIB PF00382.14 GAP90146.1 - 0.06 13.1 0.4 0.18 11.6 0.1 1.9 1 1 0 1 1 1 0 Transcription factor TFIIB repeat Cyclin PF08613.6 GAP90146.1 - 0.12 12.8 2.5 2.9 8.2 0.0 2.3 2 0 0 2 2 2 0 Cyclin Ubie_methyltran PF01209.13 GAP90147.1 - 1.9e-05 23.8 0.0 0.00097 18.3 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 GAP90147.1 - 4.3e-05 23.2 0.0 5.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP90147.1 - 0.0022 18.4 0.0 0.0057 17.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP90147.1 - 0.019 15.3 0.0 0.047 14.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 GAP90147.1 - 0.033 13.7 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain G-7-MTase PF12803.2 GAP90147.1 - 0.084 11.9 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) DUF4452 PF14618.1 GAP90148.1 - 9.9e-77 256.3 14.7 1.4e-76 255.9 10.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) KH_1 PF00013.24 GAP90149.1 - 1.7e-41 139.6 13.7 3.7e-15 55.3 1.2 3.5 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 GAP90149.1 - 5.8e-31 105.6 21.0 3e-11 42.7 1.3 4.4 5 0 0 5 5 5 3 KH domain KH_2 PF07650.12 GAP90149.1 - 2e-13 49.6 3.4 0.0031 17.0 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 GAP90149.1 - 4e-08 32.7 4.0 0.15 11.7 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 GAP90149.1 - 6.4e-06 25.8 2.1 1 9.1 0.0 3.4 3 0 0 3 3 3 3 NusA-like KH domain SLS PF14611.1 GAP90149.1 - 0.068 12.5 0.0 3.1 7.1 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial inner-membrane-bound regulator DUF3482 PF11981.3 GAP90149.1 - 1.2 8.2 3.3 2.3 7.3 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Meth_synt_2 PF01717.13 GAP90150.1 - 1.6e-10 40.4 0.0 2.8e-09 36.4 0.0 2.1 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 GAP90150.1 - 1.2e-06 28.0 0.0 0.031 13.5 0.0 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain SNARE PF05739.14 GAP90151.1 - 1.8e-12 46.7 4.4 4.1e-12 45.5 3.0 1.6 1 0 0 1 1 1 1 SNARE domain FliJ PF02050.11 GAP90151.1 - 0.015 15.3 2.9 0.015 15.3 2.0 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein DUF2968 PF11180.3 GAP90151.1 - 0.12 11.6 5.4 0.24 10.7 3.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Med9 PF07544.8 GAP90151.1 - 0.16 11.6 5.1 1.1 8.9 0.0 3.1 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 CorA PF01544.13 GAP90151.1 - 4.7 6.1 6.6 2.1 7.2 0.0 2.6 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein Glyco_hydro_42M PF08532.5 GAP90152.1 - 0.018 14.2 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain Bcr-Abl_Oligo PF09036.5 GAP90152.1 - 0.62 10.0 4.0 1.5 8.7 0.1 3.0 3 0 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain Cob_adeno_trans PF01923.13 GAP90152.1 - 1.2 8.9 5.0 1.4 8.7 0.1 2.5 1 1 2 3 3 3 0 Cobalamin adenosyltransferase adh_short PF00106.20 GAP90153.1 - 1.2e-05 25.3 0.0 4.7e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP90153.1 - 0.014 15.0 0.0 0.021 14.5 0.0 1.5 1 1 0 1 1 1 0 KR domain NAD_binding_10 PF13460.1 GAP90153.1 - 0.11 12.5 0.0 1.1 9.1 0.0 2.2 1 1 1 2 2 2 0 NADH(P)-binding Baculo_PEP_C PF04513.7 GAP90154.1 - 0.031 14.0 8.8 0.29 10.9 0.3 3.8 3 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus PMC2NT PF08066.7 GAP90154.1 - 0.16 12.3 0.8 2.2 8.6 0.0 2.9 3 0 0 3 3 3 0 PMC2NT (NUC016) domain MT0933_antitox PF14013.1 GAP90154.1 - 0.18 11.9 1.2 2.5 8.2 0.8 2.7 1 1 0 1 1 1 0 MT0933-like antitoxin protein Pex14_N PF04695.8 GAP90155.1 - 2.4e-17 63.2 0.0 8.5e-17 61.4 0.0 1.9 1 1 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region PAPA-1 PF04795.7 GAP90156.1 - 2.6e-26 92.1 1.9 2.6e-26 92.1 1.3 3.7 6 1 0 6 6 6 1 PAPA-1-like conserved region PPP4R2 PF09184.6 GAP90156.1 - 0.52 9.8 39.9 1.7 8.1 16.4 2.4 2 0 0 2 2 2 0 PPP4R2 DUF4050 PF13259.1 GAP90159.1 - 7.7e-32 109.7 0.5 2.3e-31 108.2 0.0 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF4050) Luteo_Vpg PF01659.11 GAP90159.1 - 0.16 11.6 5.7 0.64 9.7 3.9 2.0 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein p450 PF00067.17 GAP90161.1 - 7.9e-49 166.4 0.0 1.3e-48 165.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 GAP90162.1 - 2.6e-18 65.8 1.3 5e-18 64.9 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP90162.1 - 2e-09 37.2 2.3 2.7e-09 36.7 0.4 2.0 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.5 GAP90162.1 - 0.032 13.3 0.0 0.05 12.7 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Abhydrolase_6 PF12697.2 GAP90163.1 - 6.1e-17 62.2 0.5 7.8e-17 61.9 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP90163.1 - 2.9e-15 56.3 0.0 4.6e-15 55.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 GAP90163.1 - 8.8e-07 28.8 0.0 1.9e-06 27.7 0.0 1.5 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 GAP90163.1 - 8.9e-07 28.5 0.0 1.2e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 GAP90163.1 - 1.1e-06 27.4 0.0 3.3e-05 22.5 0.0 2.4 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 GAP90163.1 - 3.9e-06 26.2 0.0 1.2e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 GAP90163.1 - 0.0016 18.0 0.0 0.0064 16.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1100 PF06500.6 GAP90163.1 - 0.0018 16.9 0.0 0.0071 14.9 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) DLH PF01738.13 GAP90163.1 - 0.0023 17.2 0.0 0.0095 15.2 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.3 GAP90163.1 - 0.078 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Esterase PF00756.15 GAP90163.1 - 0.081 12.3 0.0 0.32 10.3 0.0 2.0 1 1 0 1 1 1 0 Putative esterase ketoacyl-synt PF00109.21 GAP90164.1 - 6.2e-65 219.1 0.0 1.2e-64 218.2 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 GAP90164.1 - 4.1e-53 179.7 0.2 1.2e-51 174.9 0.0 3.1 3 0 0 3 3 3 1 KR domain PS-DH PF14765.1 GAP90164.1 - 5.7e-51 173.4 0.0 9.3e-51 172.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 GAP90164.1 - 1.4e-50 172.4 0.0 2e-50 171.9 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 GAP90164.1 - 3.5e-36 124.6 4.5 6.5e-36 123.7 0.1 3.5 4 0 0 4 4 4 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAP90164.1 - 5.4e-31 106.9 0.8 1.3e-30 105.7 0.3 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 GAP90164.1 - 2.2e-19 69.2 0.0 6e-19 67.8 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAP90164.1 - 3.4e-14 53.8 0.0 1.1e-13 52.2 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP90164.1 - 1.9e-07 30.8 0.4 4.3e-07 29.6 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 GAP90164.1 - 0.0002 21.5 0.0 0.00049 20.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_26 PF13659.1 GAP90164.1 - 0.0057 16.6 0.0 0.036 14.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain ACP_syn_III PF08545.5 GAP90164.1 - 0.022 14.4 0.0 0.084 12.5 0.0 2.1 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_18 PF12847.2 GAP90164.1 - 0.045 14.3 0.0 0.79 10.3 0.0 3.1 2 0 0 2 2 2 0 Methyltransferase domain Isy1 PF06246.7 GAP90165.1 - 4.8e-85 285.0 0.0 5.6e-85 284.8 0.0 1.0 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.5 GAP90165.1 - 0.0062 16.3 0.7 0.011 15.5 0.0 1.7 2 0 0 2 2 2 1 YolD-like protein Metallophos PF00149.23 GAP90166.1 - 5.7e-09 35.6 1.7 1.1e-08 34.7 1.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Amidase PF01425.16 GAP90167.1 - 2.6e-95 319.8 0.1 3.5e-95 319.4 0.0 1.1 1 0 0 1 1 1 1 Amidase PRP38 PF03371.10 GAP90168.1 - 9e-26 90.5 0.1 1.1e-25 90.2 0.1 1.1 1 0 0 1 1 1 1 PRP38 family PRP38 PF03371.10 GAP90169.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 PRP38 family DDOST_48kD PF03345.9 GAP90170.1 - 1.1e-160 534.8 0.0 2.1e-160 533.8 0.0 1.4 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Beach PF02138.13 GAP90172.1 - 3.2e-108 361.2 0.0 4.8e-108 360.6 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 GAP90172.1 - 7.9e-12 44.9 0.4 2.3e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 GAP90172.1 - 3.2e-10 40.4 0.0 7.7e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.27 GAP90172.1 - 5.5e-07 29.2 8.8 0.053 13.4 0.5 5.0 4 0 0 4 4 4 4 WD domain, G-beta repeat Peptidase_S8 PF00082.17 GAP90173.1 - 2.8e-48 164.5 8.4 4.3e-48 163.8 5.8 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 GAP90173.1 - 1.8e-20 73.2 0.2 4.5e-20 72.0 0.1 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 Phasin PF05597.6 GAP90173.1 - 0.018 14.7 0.4 0.031 14.0 0.3 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) FimP PF09766.4 GAP90174.1 - 0.074 12.1 18.7 0.17 10.8 13.0 1.5 1 0 0 1 1 1 0 Fms-interacting protein Cellulose_synt PF03552.9 GAP90174.1 - 0.1 10.8 0.3 0.16 10.1 0.2 1.2 1 0 0 1 1 1 0 Cellulose synthase AAA_23 PF13476.1 GAP90174.1 - 0.3 11.3 12.1 0.065 13.5 5.5 1.9 2 0 0 2 2 2 0 AAA domain Plasmodium_Vir PF05795.6 GAP90174.1 - 0.63 9.1 3.0 1.7 7.7 2.1 1.7 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Serinc PF03348.10 GAP90174.1 - 1 7.9 7.2 2.2 6.9 5.0 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) Kei1 PF08552.6 GAP90174.1 - 4.7 6.8 5.5 17 5.0 3.8 1.9 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 ATP-synt_C PF00137.16 GAP90177.1 - 1.8e-26 91.7 26.9 3.6e-16 58.8 5.6 3.0 3 0 0 3 3 3 2 ATP synthase subunit C MFS_2 PF13347.1 GAP90177.1 - 0.035 12.5 5.3 0.053 11.9 3.7 1.3 1 0 0 1 1 1 0 MFS/sugar transport protein KRTAP PF11759.3 GAP90177.1 - 0.76 10.0 6.6 5.8 7.2 1.0 2.2 2 0 0 2 2 2 0 Keratin-associated matrix DUF1700 PF08006.6 GAP90177.1 - 2.4 7.4 5.2 0.38 10.0 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1700) Ldr_toxin PF13940.1 GAP90177.1 - 4.9 7.0 5.3 1.6 8.5 0.1 2.8 3 0 0 3 3 3 0 Toxin Ldr, type I toxin-antitoxin system CNH PF00780.17 GAP90178.1 - 1.8e-79 267.0 0.0 5.9e-79 265.3 0.0 1.8 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 GAP90178.1 - 1.9e-40 137.9 1.7 2.5e-40 137.5 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain RhoGEF PF00621.15 GAP90178.1 - 7.9e-37 126.8 0.1 1.7e-36 125.7 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 GAP90178.1 - 9.1e-15 54.1 0.0 1.7e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF818 PF05677.7 GAP90178.1 - 0.049 12.3 0.1 0.081 11.6 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) DUF4336 PF14234.1 GAP90179.1 - 6.2e-14 51.8 0.0 3.7e-11 42.7 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) zf-C4H2 PF10146.4 GAP90180.1 - 0.00038 20.5 4.2 0.00038 20.5 2.9 3.5 2 1 2 4 4 4 1 Zinc finger-containing protein TPR_MLP1_2 PF07926.7 GAP90180.1 - 0.0045 16.7 10.9 0.0045 16.7 7.5 5.3 3 3 0 3 3 3 1 TPR/MLP1/MLP2-like protein PMEI PF04043.10 GAP90180.1 - 0.02 14.7 0.8 0.02 14.7 0.6 3.8 4 1 1 5 5 5 0 Plant invertase/pectin methylesterase inhibitor Reo_sigmaC PF04582.7 GAP90180.1 - 0.08 12.1 5.9 4.5 6.3 0.1 3.3 3 1 1 4 4 4 0 Reovirus sigma C capsid protein Prefoldin_2 PF01920.15 GAP90180.1 - 0.092 12.5 0.3 0.092 12.5 0.2 9.2 4 2 5 10 10 10 0 Prefoldin subunit NPV_P10 PF05531.7 GAP90180.1 - 0.21 11.8 5.1 1 9.6 0.2 3.6 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 GAP90180.1 - 0.53 8.6 48.3 0.0061 15.0 4.4 3.3 3 1 0 3 3 3 0 AAA domain DUF948 PF06103.6 GAP90180.1 - 4.3 7.2 11.3 25 4.8 0.5 4.9 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) Nse4_C PF08743.5 GAP90182.1 - 5.6e-35 119.2 0.0 1.2e-34 118.1 0.0 1.6 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 GAP90182.1 - 2.1e-15 56.2 0.1 1.1e-14 54.0 0.0 2.3 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF2802 PF10975.3 GAP90182.1 - 0.074 12.8 0.2 0.32 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) PI3Ka PF00613.15 GAP90183.1 - 5.7e-58 195.1 1.0 8.2e-58 194.6 0.7 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 GAP90183.1 - 2.1e-44 151.7 0.0 1.7e-43 148.8 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 GAP90183.1 - 1.5e-33 115.6 0.0 2.3e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DOCK-C2 PF14429.1 GAP90183.1 - 4e-05 23.3 0.0 7.6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins WD40 PF00400.27 GAP90185.1 - 2.4e-24 84.2 11.8 1.6e-09 37.2 0.3 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 GAP90185.1 - 0.0023 16.2 0.6 1.1 7.4 0.0 3.5 4 0 0 4 4 4 2 Cytochrome D1 heme domain PD40 PF07676.7 GAP90185.1 - 0.026 14.2 0.8 0.079 12.6 0.1 2.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat SecE PF00584.15 GAP90186.1 - 1.8e-13 49.8 0.0 2.1e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex RRM_6 PF14259.1 GAP90187.1 - 5.8e-06 26.1 0.0 9.8e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP90187.1 - 0.0075 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAP90187.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myb_DNA-binding PF00249.26 GAP90189.1 - 5.5e-13 48.7 0.6 6.9e-07 29.2 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAP90189.1 - 1.4e-10 41.0 0.1 0.00029 20.8 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.5 GAP90189.1 - 0.063 13.0 0.1 4 7.1 0.0 2.4 2 0 0 2 2 2 0 SLIDE Ribosomal_L18e PF00828.14 GAP90190.1 - 5.7e-17 62.3 0.0 6.1e-17 62.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Ribosomal_S4e PF00900.15 GAP90191.1 - 4.5e-31 106.3 0.5 9.8e-31 105.2 0.3 1.6 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 GAP90191.1 - 2.1e-17 62.6 4.7 3.7e-17 61.8 3.3 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 GAP90191.1 - 2.4e-06 26.8 0.0 4.5e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 GAP90191.1 - 0.00027 20.5 1.2 0.00027 20.5 0.8 3.4 4 1 0 4 4 4 1 KOW motif FAD-oxidase_C PF02913.14 GAP90192.1 - 1.3e-59 201.5 0.0 2.1e-59 200.8 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 GAP90192.1 - 1e-33 115.7 0.0 1.8e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain RdRP PF05183.7 GAP90193.1 - 1.9e-176 588.1 0.0 2.5e-176 587.8 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_6 PF14259.1 GAP90193.1 - 0.00078 19.3 0.0 0.0058 16.5 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAP90193.1 - 0.0026 17.3 0.0 0.0062 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP90193.1 - 0.016 15.0 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAC PF01849.13 GAP90194.1 - 1.9e-20 72.0 0.1 2.9e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 NAC domain A_deamin PF02137.13 GAP90195.1 - 1.5e-54 185.6 0.0 2.6e-54 184.8 0.0 1.4 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain Acylphosphatase PF00708.13 GAP90195.1 - 0.026 14.6 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 Acylphosphatase Ribosomal_L24e PF01246.15 GAP90196.1 - 7.6e-29 99.3 0.4 7.6e-29 99.3 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e DUF4617 PF15395.1 GAP90196.1 - 0.04 11.9 8.1 0.047 11.7 5.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4617) Redoxin PF08534.5 GAP90197.1 - 4e-40 136.7 0.0 4.5e-40 136.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 GAP90197.1 - 6.9e-11 41.9 0.0 9.3e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family CHAT PF12770.2 GAP90198.1 - 8.2e-07 28.4 0.0 1.6e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 CHAT domain DUF1348 PF07080.6 GAP90199.1 - 4.4e-52 175.6 10.9 8.1e-51 171.5 7.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 GAP90199.1 - 1.6e-07 31.6 4.3 1.7e-07 31.5 2.6 1.4 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 GAP90199.1 - 5.1e-05 23.4 1.9 8.2e-05 22.7 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) RGS PF00615.14 GAP90200.1 - 0.012 15.7 0.0 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 Regulator of G protein signaling domain Fumble PF03630.9 GAP90201.1 - 5.1e-132 439.8 0.1 4.9e-131 436.6 0.0 1.9 1 1 0 1 1 1 1 Fumble OAR PF03826.12 GAP90203.1 - 0.009 15.4 0.0 0.022 14.2 0.0 1.7 1 0 0 1 1 1 1 OAR domain DUF4102 PF13356.1 GAP90203.1 - 0.058 13.2 0.1 0.095 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4102) 2OG-FeII_Oxy_3 PF13640.1 GAP90205.1 - 1.6e-10 41.3 0.0 2.8e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 GAP90205.1 - 8.3e-05 22.1 0.1 0.00017 21.1 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 GAP90205.1 - 0.0017 18.6 0.0 0.0028 17.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NACHT PF05729.7 GAP90207.1 - 2.1e-09 37.2 0.1 9.5e-09 35.1 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 GAP90207.1 - 2.6e-07 30.8 0.1 5.9e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 GAP90207.1 - 0.00077 18.3 0.0 0.0019 17.1 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 GAP90207.1 - 0.0011 19.1 0.0 0.0033 17.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAP90207.1 - 0.0045 17.3 0.3 0.017 15.4 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 GAP90207.1 - 0.0086 16.2 0.1 0.026 14.7 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 GAP90207.1 - 0.014 16.2 0.8 0.12 13.1 0.6 2.7 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.15 GAP90207.1 - 0.059 13.0 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF2075 PF09848.4 GAP90207.1 - 0.069 12.1 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 GAP90207.1 - 0.077 13.1 0.1 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase HET PF06985.6 GAP90207.1 - 0.52 10.4 6.2 12 6.0 2.8 2.8 2 1 0 2 2 2 0 Heterokaryon incompatibility protein (HET) UBN2 PF14223.1 GAP90208.1 - 0.0015 18.2 0.0 0.0036 17.0 0.0 1.7 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 GAP90208.1 - 0.032 13.7 0.1 0.07 12.6 0.0 1.6 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Glyco_hydro_2_N PF02837.13 GAP90209.1 - 1.6e-36 125.4 0.1 7.3e-35 119.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 GAP90209.1 - 1.2e-25 89.9 0.0 1.3e-22 80.1 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 GAP90209.1 - 5.5e-17 62.2 0.6 1.2e-16 61.1 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 GAP90209.1 - 0.00025 21.2 1.6 0.002 18.3 0.1 2.9 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain DUF3313 PF11769.3 GAP90209.1 - 0.032 13.5 0.7 0.06 12.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) PGM_PMM_IV PF00408.15 GAP90209.1 - 0.073 13.0 0.0 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain Fungal_trans PF04082.13 GAP90210.1 - 1.4e-17 63.4 0.0 2.3e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP90210.1 - 4.7e-09 36.0 12.4 8.4e-09 35.2 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.1 GAP90211.1 - 7.5e-11 42.3 0.0 1e-10 41.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding IDO PF01231.13 GAP90214.1 - 7.9e-141 469.3 0.0 9.8e-141 469.0 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Fungal_trans PF04082.13 GAP90215.1 - 2e-15 56.3 0.0 3e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP90215.1 - 8.1e-08 32.0 12.5 1.4e-07 31.2 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 GAP90216.1 - 1.1e-35 123.0 11.8 1.1e-35 123.0 8.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP90216.1 - 1.4e-12 46.9 5.2 1.4e-12 46.9 3.6 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.8 GAP90216.1 - 3.6e-05 22.0 1.4 3.6e-05 22.0 1.0 2.5 3 0 0 3 3 3 2 Transmembrane secretion effector TRI12 PF06609.8 GAP90216.1 - 0.002 16.4 0.8 0.003 15.8 0.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 GAP90216.1 - 0.0029 16.0 3.5 0.0029 16.0 2.4 3.0 2 1 1 3 3 3 1 MFS/sugar transport protein ATG22 PF11700.3 GAP90216.1 - 0.013 13.9 18.7 0.023 13.2 2.8 2.5 2 1 0 2 2 2 0 Vacuole effluxer Atg22 like DUF3087 PF11286.3 GAP90216.1 - 0.04 13.1 0.1 0.094 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) MFS_1_like PF12832.2 GAP90216.1 - 0.057 13.2 1.2 0.48 10.2 0.0 3.0 2 0 0 2 2 2 0 MFS_1 like family Cu_amine_oxid PF01179.15 GAP90217.1 - 1.7e-142 474.9 0.0 2.2e-142 474.6 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 GAP90217.1 - 6.2e-10 39.0 0.1 1.2e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 GAP90217.1 - 0.0001 22.3 0.0 0.00022 21.1 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Glyco_hydro_3 PF00933.16 GAP90218.1 - 3e-91 305.5 0.0 4e-91 305.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAP90218.1 - 3.7e-53 180.3 0.0 1.2e-52 178.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAP90218.1 - 1.9e-24 85.3 0.3 3.9e-24 84.3 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain SSF PF00474.12 GAP90219.1 - 1e-20 73.7 28.7 1.8e-20 73.0 19.9 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Glyco_hydro_88 PF07470.8 GAP90220.1 - 8.8e-80 268.2 1.5 1e-79 268.0 1.0 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 MFS_1 PF07690.11 GAP90221.1 - 2.6e-30 105.3 21.6 2.6e-30 105.3 15.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2929 PF11151.3 GAP90221.1 - 0.0055 16.7 0.5 0.033 14.2 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2929) DUF4133 PF13571.1 GAP90221.1 - 0.12 12.5 4.8 4.1 7.6 1.4 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) RRM_1 PF00076.17 GAP90222.1 - 6.5e-15 54.5 0.0 9.4e-15 54.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP90222.1 - 1e-12 47.8 0.0 1.6e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP90222.1 - 1.4e-07 31.2 0.0 2.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cupin_2 PF07883.6 GAP90223.1 - 0.014 14.8 0.0 0.29 10.6 0.0 2.3 1 1 0 1 1 1 0 Cupin domain Glyco_hydro_16 PF00722.16 GAP90224.1 - 9.8e-18 64.0 0.1 3.1e-17 62.4 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.1 GAP90225.1 - 5.6e-47 159.9 6.3 1.4e-46 158.6 4.2 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAP90225.1 - 1.5e-06 28.1 0.0 4.2e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 GAP90225.1 - 3.5e-06 26.8 0.0 1.9e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 GAP90225.1 - 0.00084 18.6 0.0 0.0017 17.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.16 GAP90226.1 - 7.8e-33 113.3 4.0 1.3e-32 112.6 2.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Peptidase_S41 PF03572.13 GAP90227.1 - 0.0024 17.3 0.0 0.0043 16.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 Methyltransf_23 PF13489.1 GAP90229.1 - 6.3e-13 48.7 0.0 1e-12 48.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP90229.1 - 6.7e-09 36.1 0.0 1.3e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP90229.1 - 3.7e-08 33.0 0.0 6.9e-08 32.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP90229.1 - 2.4e-07 31.3 0.0 6.3e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAP90229.1 - 7.8e-05 21.8 0.0 0.00053 19.0 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 GAP90229.1 - 0.0008 19.4 0.0 0.0023 17.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP90229.1 - 0.0012 19.2 0.0 0.0068 16.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAP90229.1 - 0.027 13.8 0.0 0.16 11.3 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase small domain Methyltransf_16 PF10294.4 GAP90229.1 - 0.053 12.9 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase QRPTase_C PF01729.14 GAP90230.1 - 2.8e-54 183.1 0.1 3.4e-54 182.8 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 GAP90230.1 - 2e-20 72.4 0.0 4.9e-20 71.1 0.0 1.7 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain PRAI PF00697.17 GAP90230.1 - 0.024 14.2 0.1 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase MFS_1 PF07690.11 GAP90231.1 - 6.2e-39 133.6 24.4 8.8e-39 133.1 16.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Gln-synt_C PF00120.19 GAP90232.1 - 5.4e-61 205.9 0.0 6.9e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain adh_short PF00106.20 GAP90233.1 - 1.8e-27 96.2 1.5 2.6e-27 95.7 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP90233.1 - 5.6e-14 52.4 0.0 8e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP90233.1 - 1.2e-11 44.6 0.7 1.8e-11 44.0 0.5 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 GAP90233.1 - 0.00064 19.4 0.1 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 GAP90233.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAP90233.1 - 0.018 13.9 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 GAP90233.1 - 0.04 12.6 0.0 0.32 9.6 0.0 2.0 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family UDPG_MGDP_dh_N PF03721.9 GAP90233.1 - 0.074 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Saccharop_dh PF03435.13 GAP90233.1 - 0.078 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Methyltransf_12 PF08242.7 GAP90233.1 - 0.13 12.7 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Eno-Rase_NADH_b PF12242.3 GAP90233.1 - 1.2 8.9 3.6 1.1 9.0 0.7 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ICL PF00463.16 GAP90234.1 - 1.5e-197 657.0 0.1 1.7e-197 656.8 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family Arg_repressor_C PF02863.13 GAP90234.1 - 0.037 13.5 0.0 0.088 12.2 0.0 1.6 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain Citrate_synt PF00285.16 GAP90235.1 - 3e-102 341.9 0.0 3.6e-102 341.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Glyco_hydro_98M PF08306.6 GAP90235.1 - 0.069 11.8 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 DUF4360 PF14273.1 GAP90236.1 - 2.2e-72 242.5 4.0 2.5e-72 242.3 2.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) LigB PF02900.13 GAP90237.1 - 9.9e-49 165.7 0.2 1.2e-48 165.5 0.1 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Metallophos_C PF14008.1 GAP90237.1 - 0.011 15.7 0.1 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 Iron/zinc purple acid phosphatase-like protein C Abhydrolase_2 PF02230.11 GAP90238.1 - 1.8e-60 204.0 0.0 2.2e-60 203.7 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 GAP90238.1 - 1.6e-08 34.3 0.1 5.3e-08 32.7 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP90238.1 - 6.2e-08 32.8 0.6 2.1e-05 24.5 0.2 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.13 GAP90238.1 - 0.00039 19.7 0.0 0.00063 19.0 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF2920 PF11144.3 GAP90238.1 - 0.00045 19.3 0.1 0.28 10.1 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2920) Abhydrolase_3 PF07859.8 GAP90238.1 - 0.00058 19.4 0.1 0.1 12.1 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.8 GAP90238.1 - 0.001 18.5 0.0 0.0064 15.9 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 GAP90238.1 - 0.0044 16.2 0.5 0.13 11.4 0.0 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family Lipase_3 PF01764.20 GAP90238.1 - 0.039 13.5 0.0 0.09 12.3 0.0 1.7 1 1 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.3 GAP90238.1 - 0.051 12.9 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Cutinase PF01083.17 GAP90238.1 - 0.063 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Cutinase IMD PF08397.6 GAP90239.1 - 0.00042 19.6 1.2 0.0092 15.3 0.2 2.1 2 0 0 2 2 2 2 IRSp53/MIM homology domain DUF1687 PF07955.6 GAP90241.1 - 1.1e-21 77.1 0.2 2e-21 76.3 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.10 GAP90241.1 - 0.12 12.4 0.0 1.3 9.1 0.0 2.2 1 1 0 1 1 1 0 ArsC family Peptidase_M30 PF10460.4 GAP90242.1 - 0.12 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase M30 CAS_CSE1 PF03378.10 GAP90242.1 - 0.82 7.9 0.0 1.2 7.3 0.0 1.1 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus L51_S25_CI-B8 PF05047.11 GAP90243.1 - 4.4e-14 51.9 0.0 5.5e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain HopJ PF08888.6 GAP90244.1 - 0.16 11.9 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 HopJ type III effector protein AAA PF00004.24 GAP90245.1 - 7.6e-31 107.0 0.0 1.8e-30 105.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAP90245.1 - 3.4e-05 23.9 0.2 0.0092 16.1 0.1 2.9 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 GAP90245.1 - 0.00014 22.6 0.0 0.00035 21.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAP90245.1 - 0.00035 20.4 0.1 0.00092 19.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 GAP90245.1 - 0.0015 18.4 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAP90245.1 - 0.0019 18.1 0.1 0.35 10.8 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 GAP90245.1 - 0.0036 16.7 0.0 0.0061 16.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 GAP90245.1 - 0.0052 16.5 0.1 0.022 14.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PhoH PF02562.11 GAP90245.1 - 0.019 14.1 0.1 1.1 8.4 0.1 2.3 1 1 1 2 2 2 0 PhoH-like protein AAA_19 PF13245.1 GAP90245.1 - 0.021 14.5 0.7 0.048 13.4 0.5 1.5 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 GAP90245.1 - 0.034 14.3 0.4 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 RNA helicase RuvB_N PF05496.7 GAP90245.1 - 0.038 13.0 0.0 0.071 12.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 GAP90245.1 - 0.053 13.8 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 GAP90245.1 - 0.062 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 GAP90245.1 - 0.077 12.3 0.7 0.3 10.4 0.5 1.9 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.16 GAP90245.1 - 0.093 11.8 0.2 0.19 10.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 GAP90245.1 - 0.16 10.6 0.1 0.31 9.7 0.0 1.5 2 0 0 2 2 2 0 TIP49 C-terminus AAA_3 PF07726.6 GAP90245.1 - 0.17 11.5 0.0 3.9 7.0 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 GAP90247.1 - 9e-28 97.1 0.0 4.9e-14 52.6 0.0 3.5 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 GAP90247.1 - 4.1e-12 45.8 0.9 0.00057 19.3 0.1 3.6 3 1 0 3 3 3 3 IstB-like ATP binding protein AAA_22 PF13401.1 GAP90247.1 - 4.1e-10 39.9 0.1 0.19 11.8 0.1 5.7 3 2 0 3 3 3 3 AAA domain AAA_5 PF07728.9 GAP90247.1 - 6.9e-10 38.7 0.1 0.006 16.3 0.0 3.9 3 1 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 GAP90247.1 - 4.4e-09 35.9 0.8 0.009 15.7 0.1 3.9 3 0 0 3 3 3 2 Part of AAA domain RuvB_N PF05496.7 GAP90247.1 - 4.9e-08 32.3 0.2 0.31 10.0 0.0 4.4 4 1 0 4 4 4 3 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 GAP90247.1 - 1.8e-07 30.5 0.0 0.14 11.2 0.0 3.3 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 GAP90247.1 - 1.9e-06 27.8 1.0 0.054 13.3 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_17 PF13207.1 GAP90247.1 - 1.4e-05 25.9 15.7 0.02 15.7 0.6 5.5 4 2 0 4 4 3 2 AAA domain AAA_16 PF13191.1 GAP90247.1 - 1.5e-05 25.0 0.1 0.51 10.2 0.0 4.3 3 1 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.1 GAP90247.1 - 2.8e-05 23.8 0.1 2 7.9 0.0 3.9 3 1 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.1 GAP90247.1 - 7.7e-05 22.7 0.0 0.64 10.0 0.0 4.1 3 1 0 3 3 3 1 Sigma-54 interaction domain RNA_helicase PF00910.17 GAP90247.1 - 0.00012 22.2 0.0 0.16 12.1 0.0 3.4 4 0 0 4 4 3 1 RNA helicase Sigma54_activat PF00158.21 GAP90247.1 - 0.00013 21.4 0.2 2.5 7.5 0.0 4.6 4 1 0 4 4 4 1 Sigma-54 interaction domain Torsin PF06309.6 GAP90247.1 - 0.00017 21.4 0.0 0.59 10.0 0.0 3.3 3 0 0 3 3 3 1 Torsin AAA_28 PF13521.1 GAP90247.1 - 0.0017 18.3 3.7 0.9 9.4 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.1 GAP90247.1 - 0.002 17.7 1.0 0.37 10.3 0.1 3.3 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 GAP90247.1 - 0.0054 17.0 9.5 0.54 10.5 0.0 4.8 5 0 0 5 5 4 2 AAA domain MCM PF00493.18 GAP90247.1 - 0.01 14.6 0.0 1.8 7.2 0.0 2.6 3 0 0 3 3 3 0 MCM2/3/5 family AAA_11 PF13086.1 GAP90247.1 - 0.16 11.5 16.1 0.21 11.1 0.0 4.7 4 3 0 4 4 4 0 AAA domain WD40 PF00400.27 GAP90248.1 - 1.7e-79 259.0 41.9 7.1e-11 41.5 0.0 12.1 12 0 0 12 12 12 10 WD domain, G-beta repeat PD40 PF07676.7 GAP90248.1 - 5.7e-07 29.0 1.8 18 5.1 0.0 7.3 8 0 0 8 8 8 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 GAP90248.1 - 0.00014 20.2 0.3 0.034 12.4 0.0 3.5 3 0 0 3 3 3 2 Cytochrome D1 heme domain eIF2A PF08662.6 GAP90248.1 - 0.001 18.8 0.0 0.36 10.5 0.0 4.0 4 1 1 5 5 5 1 Eukaryotic translation initiation factor eIF2A NACHT PF05729.7 GAP90248.1 - 0.0064 16.1 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Proteasome_A_N PF10584.4 GAP90248.1 - 5 6.5 11.2 89 2.5 0.0 5.8 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature adh_short PF00106.20 GAP90250.1 - 6.6e-11 42.4 0.0 8.5e-11 42.0 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP90250.1 - 0.00031 20.4 0.0 0.00037 20.2 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAP90250.1 - 0.023 14.4 0.0 0.024 14.4 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Ldh_1_N PF00056.18 GAP90250.1 - 0.055 13.3 0.0 0.076 12.8 0.0 1.1 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain FAD_binding_4 PF01565.18 GAP90251.1 - 4.5e-18 65.0 2.8 8.3e-18 64.2 1.3 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 GAP90251.1 - 1.6e-08 34.3 0.9 4.7e-08 32.8 0.6 1.8 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.17 GAP90252.1 - 2.7e-44 151.4 0.0 3.4e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UbiA PF01040.13 GAP90253.1 - 1.3e-21 77.0 7.6 1.6e-21 76.6 5.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF1206 PF06724.6 GAP90254.1 - 0.071 12.8 0.5 0.071 12.8 0.3 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) AceK PF06315.6 GAP90254.1 - 0.083 11.1 0.0 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) FAD_binding_4 PF01565.18 GAP90255.1 - 2.1e-23 82.3 2.4 3.5e-23 81.6 1.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP90255.1 - 0.0058 16.5 0.1 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.11 GAP90256.1 - 5.4e-37 127.3 52.9 5.4e-37 127.3 36.7 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAP90256.1 - 2e-11 42.8 13.6 2e-11 42.8 9.4 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAP90256.1 - 3.2e-10 39.1 13.0 3.2e-10 39.1 9.0 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter p450 PF00067.17 GAP90257.1 - 7.5e-40 136.8 0.0 1e-39 136.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 LysM PF01476.15 GAP90258.1 - 9.1e-08 31.8 0.0 0.0012 18.6 0.0 2.4 2 0 0 2 2 2 2 LysM domain Csm1 PF12539.3 GAP90259.1 - 2.5e-25 88.7 0.4 6.5e-25 87.4 0.0 1.9 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 Spc7 PF08317.6 GAP90259.1 - 0.0027 16.4 9.8 0.0071 15.0 6.8 1.7 1 0 0 1 1 1 1 Spc7 kinetochore protein NPV_P10 PF05531.7 GAP90259.1 - 0.07 13.3 0.9 0.28 11.4 0.4 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 GAP90259.1 - 0.18 10.9 4.3 0.43 9.7 2.5 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein LMBR1 PF04791.11 GAP90259.1 - 4.4 5.7 4.4 7.9 4.9 3.0 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein PigN PF04987.9 GAP90260.1 - 3e-159 530.4 26.2 3e-159 530.4 18.1 1.4 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 GAP90260.1 - 2.6e-09 36.8 1.2 2.7e-07 30.2 0.1 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 GAP90260.1 - 4.7e-09 35.8 0.1 7.2e-09 35.2 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 GAP90260.1 - 0.0005 19.5 0.0 0.00082 18.8 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF3975 PF13126.1 GAP90260.1 - 0.49 10.5 4.1 0.18 11.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3975) Fungal_trans PF04082.13 GAP90261.1 - 7.1e-36 123.4 0.0 6.1e-35 120.3 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP90261.1 - 3.8e-08 33.0 9.2 7e-08 32.2 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Leu_zip PF15294.1 GAP90261.1 - 0.15 11.1 0.2 0.23 10.5 0.1 1.1 1 0 0 1 1 1 0 Leucine zipper LysM PF01476.15 GAP90262.1 - 0.068 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 LysM domain NAD_binding_2 PF03446.10 GAP90263.1 - 9.6e-31 106.8 0.1 1.4e-30 106.3 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 GAP90263.1 - 7e-10 39.2 0.1 1.5e-09 38.1 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 GAP90263.1 - 3.5e-09 36.8 0.1 5.1e-09 36.3 0.1 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.1 GAP90263.1 - 1.7e-07 31.2 0.1 2.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase GFO_IDH_MocA PF01408.17 GAP90263.1 - 0.0038 17.7 0.0 0.0066 16.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold OCD_Mu_crystall PF02423.10 GAP90263.1 - 0.0039 15.9 0.1 0.0053 15.5 0.1 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family TrkA_N PF02254.13 GAP90263.1 - 0.0069 16.3 0.2 0.017 15.0 0.1 1.6 1 1 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 GAP90263.1 - 0.014 14.8 0.6 0.045 13.1 0.4 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short PF00106.20 GAP90263.1 - 0.014 15.3 0.1 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Saccharop_dh PF03435.13 GAP90263.1 - 0.016 14.1 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase KR PF08659.5 GAP90263.1 - 0.022 14.4 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.19 GAP90263.1 - 0.022 15.0 0.0 0.065 13.5 0.0 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain IlvN PF07991.7 GAP90263.1 - 0.076 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain P34-Arc PF04045.9 GAP90264.1 - 2.6e-102 341.2 0.4 3.2e-102 340.9 0.3 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Hemerythrin PF01814.18 GAP90264.1 - 0.3 11.2 3.5 5 7.2 0.3 2.3 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain WD40 PF00400.27 GAP90265.1 - 2.4e-69 226.9 20.9 1.1e-08 34.6 0.0 11.3 11 0 0 11 11 11 9 WD domain, G-beta repeat Utp12 PF04003.7 GAP90265.1 - 5.6e-18 64.8 0.1 9e-18 64.1 0.1 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Nucleoporin_N PF08801.6 GAP90265.1 - 9.1e-05 21.3 3.1 2 7.0 0.1 5.0 3 1 0 5 5 5 2 Nup133 N terminal like BBS2_Mid PF14783.1 GAP90265.1 - 0.00039 20.1 0.5 14 5.4 0.0 6.1 6 1 1 7 7 7 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 GAP90265.1 - 0.007 14.5 0.6 0.61 8.1 0.0 3.3 3 1 0 4 4 4 1 Nucleoporin Nup120/160 zf-RING_2 PF13639.1 GAP90266.1 - 2e-13 49.9 3.3 3.8e-13 49.0 2.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAP90266.1 - 6.6e-12 45.3 0.6 1.2e-11 44.5 0.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 GAP90266.1 - 8.8e-07 28.8 2.4 2.2e-06 27.5 1.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAP90266.1 - 9.3e-07 28.6 0.4 9.3e-07 28.6 0.2 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 GAP90266.1 - 4.6e-06 26.2 3.1 7.7e-06 25.5 2.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 GAP90266.1 - 2.6e-05 23.7 2.2 4.7e-05 22.9 1.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAP90266.1 - 0.00011 21.7 3.6 0.00021 20.9 2.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAP90266.1 - 0.00024 20.7 1.8 0.00063 19.4 1.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.3 GAP90266.1 - 0.0015 18.4 3.9 0.026 14.5 2.7 2.2 1 1 0 1 1 1 1 FANCL C-terminal domain Baculo_RING PF05883.6 GAP90266.1 - 0.097 12.5 0.2 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-C3HC4_4 PF15227.1 GAP90266.1 - 1.5 8.7 4.2 4.2 7.3 2.9 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Methyltransf_23 PF13489.1 GAP90267.1 - 5.2e-11 42.5 0.0 8.4e-11 41.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP90267.1 - 1.8e-09 37.3 0.0 2.7e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP90267.1 - 6.9e-09 36.0 0.0 1.8e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP90267.1 - 4.3e-08 33.7 0.0 7.8e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP90267.1 - 6.8e-06 26.4 0.0 1.4e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP90267.1 - 0.00011 22.2 0.0 0.00028 20.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP90267.1 - 0.00051 19.2 0.0 0.0008 18.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.13 GAP90267.1 - 0.00069 18.9 0.0 0.0014 17.9 0.0 1.4 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_25 PF13649.1 GAP90267.1 - 0.0067 16.7 0.0 0.021 15.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain DUF3775 PF12616.3 GAP90267.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3775) Glyco_transf_4 PF13439.1 GAP90267.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase Family 4 zf-C2H2_4 PF13894.1 GAP90268.1 - 0.0015 18.7 4.5 0.27 11.6 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 GAP90268.1 - 0.0015 18.7 3.8 0.21 12.0 0.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAP90268.1 - 0.07 13.4 0.4 0.24 11.7 0.0 2.0 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 GAP90268.1 - 0.26 11.2 2.8 11 6.0 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Cullin PF00888.17 GAP90269.1 - 8.4e-50 169.9 0.0 1.5e-49 169.0 0.0 1.3 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 GAP90269.1 - 6.8e-19 67.8 0.0 1.4e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 ABC_tran PF00005.22 GAP90270.1 - 8.7e-37 126.4 0.0 1.2e-20 74.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAP90270.1 - 1.4e-21 77.1 4.3 3.1e-21 76.0 3.0 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.1 GAP90270.1 - 9.6e-07 28.9 1.4 0.01 15.8 0.0 2.8 2 1 1 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 GAP90270.1 - 4.2e-06 26.1 0.3 0.0042 16.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 GAP90270.1 - 3.2e-05 23.5 0.1 0.23 10.8 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF258 PF03193.11 GAP90270.1 - 0.00013 21.1 0.6 0.23 10.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF258 T2SE PF00437.15 GAP90270.1 - 0.0014 17.6 0.1 0.66 8.8 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 GAP90270.1 - 0.0034 16.8 0.3 0.16 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 GAP90270.1 - 0.0043 16.9 0.2 2.6 8.0 0.1 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 GAP90270.1 - 0.0047 16.3 1.5 1.4 8.3 0.1 2.3 2 0 0 2 2 2 2 AAA-like domain SMC_N PF02463.14 GAP90270.1 - 0.0067 15.6 0.0 0.25 10.5 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain cobW PF02492.14 GAP90270.1 - 0.015 14.7 0.6 2.3 7.6 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 GAP90270.1 - 0.015 15.7 0.7 0.23 11.9 0.1 2.3 2 0 0 2 2 2 0 Miro-like protein AAA_22 PF13401.1 GAP90270.1 - 0.019 15.1 3.8 2.8 8.0 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 GAP90270.1 - 0.041 13.4 0.5 5.8 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.9 GAP90270.1 - 0.047 12.6 0.1 0.13 11.1 0.0 1.6 2 0 0 2 2 2 0 PIF1-like helicase Dynamin_N PF00350.18 GAP90270.1 - 0.08 12.7 0.4 2.3 8.0 0.1 2.2 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.7 GAP90270.1 - 0.098 12.3 1.5 11 5.6 0.1 2.5 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 GAP90270.1 - 0.12 11.4 0.3 6.6 5.7 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin AAA_21 PF13304.1 GAP90270.1 - 0.13 12.1 0.1 0.96 9.3 0.0 2.3 3 0 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 GAP90270.1 - 0.19 11.3 0.6 19 4.8 0.0 2.6 2 1 0 2 2 2 0 Archaeal ATPase AAA_23 PF13476.1 GAP90270.1 - 0.3 11.3 0.0 6 7.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.4 GAP90270.1 - 0.38 9.6 2.1 4.2 6.2 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Viral_helicase1 PF01443.13 GAP90270.1 - 0.44 10.0 0.2 8.7 5.7 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 GAP90270.1 - 0.45 9.4 1.1 10 4.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ArgK PF03308.11 GAP90270.1 - 2.8 6.6 7.7 6.7 5.4 0.0 3.0 3 0 0 3 3 3 0 ArgK protein DUF3035 PF11233.3 GAP90271.1 - 0.13 12.2 1.8 0.14 12.2 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3035) Baculo_PEP_C PF04513.7 GAP90272.1 - 0.0031 17.3 0.5 0.0061 16.3 0.4 1.5 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus WEMBL PF05701.6 GAP90272.1 - 0.043 12.2 0.2 0.058 11.8 0.2 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Phage_antitermQ PF06530.7 GAP90272.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Phage antitermination protein Q Ribosomal_L9_N PF01281.14 GAP90273.1 - 3.2e-07 29.4 0.0 6.4e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.9 GAP90273.1 - 0.012 15.6 0.0 0.89 9.6 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L9, C-terminal domain ATG11 PF10377.4 GAP90274.1 - 7.4e-38 129.3 1.5 1.9e-37 128.0 0.0 2.6 2 0 0 2 2 2 1 Autophagy-related protein 11 MAD PF05557.8 GAP90274.1 - 0.00041 18.6 16.9 0.00041 18.6 11.7 3.7 2 1 1 4 4 4 1 Mitotic checkpoint protein DUF869 PF05911.6 GAP90274.1 - 0.00053 18.3 14.6 0.00053 18.3 10.1 3.4 1 1 2 3 3 3 2 Plant protein of unknown function (DUF869) Tropomyosin PF00261.15 GAP90274.1 - 0.00087 18.4 11.3 0.00087 18.4 7.8 7.0 4 1 3 7 7 7 1 Tropomyosin TMF_DNA_bd PF12329.3 GAP90274.1 - 0.0012 18.5 4.7 0.0012 18.5 3.3 8.8 6 2 5 11 11 11 2 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 GAP90274.1 - 0.0034 16.5 3.0 0.0034 16.5 2.1 5.8 3 2 5 8 8 8 2 Reovirus sigma C capsid protein Laminin_II PF06009.7 GAP90274.1 - 0.043 13.5 0.1 0.043 13.5 0.1 8.4 5 2 5 10 10 10 0 Laminin Domain II Spc7 PF08317.6 GAP90274.1 - 0.049 12.2 61.3 0.3 9.7 8.9 6.1 3 2 3 7 7 7 0 Spc7 kinetochore protein Filament PF00038.16 GAP90274.1 - 0.52 9.7 63.2 0.27 10.6 20.9 5.1 2 1 2 4 4 4 0 Intermediate filament protein DUF1664 PF07889.7 GAP90274.1 - 7.3 6.4 41.8 3.1 7.5 1.4 7.7 3 3 4 7 7 7 0 Protein of unknown function (DUF1664) zf-C4H2 PF10146.4 GAP90274.1 - 8.4 6.3 45.4 0.098 12.6 10.0 5.6 2 2 4 6 6 6 0 Zinc finger-containing protein CENP-H PF05837.7 GAP90275.1 - 3.4e-26 91.4 0.3 3.7e-24 84.9 0.0 2.1 2 0 0 2 2 2 1 Centromere protein H (CENP-H) IncA PF04156.9 GAP90275.1 - 0.18 11.3 2.3 1.4 8.4 0.3 2.2 2 0 0 2 2 2 0 IncA protein DUF1192 PF06698.6 GAP90275.1 - 0.19 11.5 2.9 1.3 8.8 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) ATG16 PF08614.6 GAP90275.1 - 0.23 11.2 4.6 1.2 8.9 0.3 2.5 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Myosin_tail_1 PF01576.14 GAP90275.1 - 0.32 8.6 4.1 0.079 10.6 0.4 1.6 2 0 0 2 2 2 0 Myosin tail Spc24 PF08286.6 GAP90275.1 - 0.49 10.1 3.1 0.39 10.4 0.2 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 bZIP_2 PF07716.10 GAP90275.1 - 4.5 7.1 8.3 18 5.2 1.5 2.7 3 0 0 3 3 3 0 Basic region leucine zipper HMG_box PF00505.14 GAP90276.1 - 7.1e-25 87.0 0.8 9.8e-25 86.6 0.6 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 GAP90276.1 - 7.5e-19 67.8 1.3 1.1e-18 67.3 0.9 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 GAP90276.1 - 0.00053 19.7 0.7 0.001 18.8 0.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 GAP90276.1 - 0.042 14.0 0.1 0.12 12.5 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) DEADboxA PF12343.3 GAP90276.1 - 0.18 12.1 2.8 3.2 8.0 2.0 2.2 1 1 0 1 1 1 0 Cold shock protein DEAD box A CorA PF01544.13 GAP90278.1 - 2.8e-05 23.3 0.0 5.7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein AAA PF00004.24 GAP90279.1 - 3.3e-17 62.9 0.0 6.7e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAP90279.1 - 0.0003 20.9 1.0 0.021 14.9 0.4 3.0 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAP90279.1 - 0.00066 20.4 0.1 0.0042 17.9 0.0 2.5 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 GAP90279.1 - 0.00082 19.4 0.0 0.0024 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 GAP90279.1 - 0.00093 18.9 0.0 0.0024 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 GAP90279.1 - 0.0016 18.7 0.4 0.0079 16.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 GAP90279.1 - 0.011 15.6 0.0 0.068 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 GAP90279.1 - 0.011 14.7 0.0 0.021 13.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus CPT PF07931.7 GAP90279.1 - 0.027 14.1 0.0 0.26 10.8 0.0 2.3 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 GAP90279.1 - 0.047 13.5 0.1 0.15 11.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.6 GAP90279.1 - 0.11 12.1 0.2 0.75 9.4 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mago-bind PF09282.5 GAP90279.1 - 7.4 6.2 7.4 6.9 6.3 3.0 2.4 2 0 0 2 2 2 0 Mago binding ProSAAS PF07259.7 GAP90280.1 - 0.097 12.2 0.4 0.19 11.2 0.3 1.4 1 0 0 1 1 1 0 ProSAAS precursor Exo_endo_phos PF03372.18 GAP90281.1 - 2e-06 27.9 5.6 1.2e-05 25.3 3.9 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Lactamase_B PF00753.22 GAP90281.1 - 0.028 14.0 0.3 0.33 10.5 0.2 2.2 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF221 PF02714.10 GAP90282.1 - 1.7e-93 313.0 17.1 2.7e-93 312.3 11.8 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 GAP90282.1 - 1.2e-40 138.6 2.7 3.2e-40 137.2 1.8 1.8 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 GAP90282.1 - 2.5e-15 56.7 0.0 4.9e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) PAPS_reduct PF01507.14 GAP90284.1 - 1e-27 97.0 0.0 6.8e-21 74.8 0.0 2.1 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family E1-E2_ATPase PF00122.15 GAP90285.1 - 8.1e-61 204.9 4.7 1.8e-60 203.8 3.2 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAP90285.1 - 1.1e-34 119.5 2.5 1.1e-34 119.5 1.8 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAP90285.1 - 7e-28 98.5 0.1 3.5e-23 83.1 0.1 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAP90285.1 - 1.8e-22 79.0 0.0 3.5e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 GAP90285.1 - 1.4e-16 59.7 0.1 6.4e-16 57.5 0.1 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 GAP90285.1 - 8.9e-13 48.8 0.0 2.6e-12 47.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAP90285.1 - 1.2e-06 28.3 0.1 8.3e-05 22.2 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3733 PF12534.3 GAP90285.1 - 0.023 13.9 0.1 0.079 12.2 0.0 1.9 1 0 0 1 1 1 0 Leucine-rich repeat containing protein 8 PHD PF00628.24 GAP90287.1 - 3.7e-08 32.9 9.0 6.9e-08 32.0 6.2 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 GAP90287.1 - 0.026 13.8 5.4 0.051 12.8 3.7 1.5 1 0 0 1 1 1 0 PHD-finger HMG_box PF00505.14 GAP90288.1 - 0.00039 20.6 0.3 0.019 15.1 0.3 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box MAT_Alpha1 PF04769.7 GAP90288.1 - 0.039 13.2 1.7 0.045 13.0 0.0 1.7 2 0 0 2 2 2 0 Mating-type protein MAT alpha 1 Hamartin PF04388.7 GAP90288.1 - 0.097 11.3 0.4 0.11 11.1 0.3 1.1 1 0 0 1 1 1 0 Hamartin protein Med3 PF11593.3 GAP90288.1 - 0.14 11.3 6.1 0.17 11.0 4.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Sec20 PF03908.8 GAP90290.1 - 5e-17 61.3 0.3 5e-17 61.3 0.2 2.6 4 0 0 4 4 4 1 Sec20 Syntaxin_2 PF14523.1 GAP90290.1 - 0.095 12.7 5.3 0.033 14.2 1.0 2.1 2 0 0 2 2 2 0 Syntaxin-like protein DASH_Dam1 PF08653.5 GAP90290.1 - 1.4 8.7 4.6 7.4 6.4 0.2 2.8 3 0 0 3 3 3 0 DASH complex subunit Dam1 OmpH PF03938.9 GAP90290.1 - 5.8 6.8 7.9 2.9 7.8 2.2 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) MRP_L53 PF10780.4 GAP90291.1 - 7.9e-19 67.3 0.2 1.1e-18 66.9 0.2 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Pyrophosphatase PF00719.14 GAP90292.1 - 1.3e-52 177.4 0.0 2.6e-52 176.4 0.1 1.4 2 0 0 2 2 2 1 Inorganic pyrophosphatase Zn_clus PF00172.13 GAP90293.1 - 1.9e-05 24.4 7.1 3.7e-05 23.5 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PC4 PF02229.11 GAP90294.1 - 0.04 13.1 0.0 0.062 12.5 0.0 1.2 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) Ppx-GppA PF02541.11 GAP90295.1 - 1.3e-35 122.9 0.0 3.4e-35 121.6 0.0 1.6 1 1 0 1 1 1 1 Ppx/GppA phosphatase family Peptidase_C15 PF01470.12 GAP90296.1 - 0.0073 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Pyroglutamyl peptidase Peptidase_C15 PF01470.12 GAP90297.1 - 2.4e-05 24.2 0.0 5.8e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Pyroglutamyl peptidase Oxidored_FMN PF00724.15 GAP90298.1 - 9.1e-74 248.4 0.0 1.3e-73 247.9 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF2650 PF10853.3 GAP90299.1 - 0.11 11.9 0.1 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) Cytochrom_C1 PF02167.10 GAP90300.1 - 7.4e-81 270.9 0.0 8.7e-81 270.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 GAP90300.1 - 0.035 14.2 0.0 0.066 13.3 0.0 1.6 1 1 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 GAP90300.1 - 0.066 14.0 0.5 0.24 12.2 0.1 2.2 2 1 0 2 2 2 0 Cytochrome c HhH-GPD PF00730.20 GAP90301.1 - 0.041 14.1 0.0 0.1 12.8 0.0 1.7 2 0 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein DAHP_synth_1 PF00793.15 GAP90302.1 - 9.5e-90 299.9 0.1 1.2e-89 299.5 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Far-17a_AIG1 PF04750.9 GAP90303.1 - 8.7e-58 194.7 11.8 1e-57 194.6 8.2 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Got1 PF04178.7 GAP90303.1 - 0.85 9.7 9.0 1.4 9.0 3.8 2.4 2 0 0 2 2 2 0 Got1/Sft2-like family Pro_isomerase PF00160.16 GAP90304.1 - 4.4e-51 173.1 0.2 1.5e-50 171.4 0.1 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 GAP90304.1 - 2e-15 55.9 1.2 1.3e-08 34.3 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Fungal_trans_2 PF11951.3 GAP90305.1 - 3e-55 187.4 0.0 4.3e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP90305.1 - 1.9e-08 34.0 8.3 1.9e-08 34.0 5.8 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMN_dh PF01070.13 GAP90306.1 - 2.9e-126 421.1 0.1 3.4e-126 420.8 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 GAP90306.1 - 1e-05 24.6 1.4 1.5e-05 24.0 0.9 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 GAP90306.1 - 4.9e-05 22.5 0.9 0.026 13.5 0.3 2.3 1 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 GAP90306.1 - 0.0003 19.8 3.0 0.0005 19.0 0.4 2.2 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 GAP90306.1 - 0.0012 18.0 1.9 0.002 17.3 1.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IGPS PF00218.16 GAP90306.1 - 0.0033 16.5 0.0 0.0081 15.2 0.0 1.7 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase His_biosynth PF00977.16 GAP90306.1 - 0.0081 15.4 0.1 0.036 13.3 0.1 2.0 1 1 1 2 2 2 1 Histidine biosynthesis protein PcrB PF01884.12 GAP90306.1 - 0.033 13.4 0.0 3.1 6.9 0.0 2.8 2 1 1 3 3 3 0 PcrB family Sld5 PF05916.6 GAP90307.1 - 3.8e-09 36.7 0.2 6.1e-09 36.1 0.1 1.4 1 0 0 1 1 1 1 GINS complex protein Abhydrolase_6 PF12697.2 GAP90308.1 - 2.2e-23 83.3 3.7 3.4e-23 82.7 2.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP90308.1 - 1.4e-11 44.3 0.1 2.8e-11 43.3 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP90308.1 - 2.2e-06 27.3 0.0 4e-05 23.2 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 GAP90308.1 - 4.1e-05 23.9 0.2 6.8e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 GAP90308.1 - 0.016 15.0 0.1 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase PGAP1 PF07819.8 GAP90308.1 - 0.041 13.4 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DLH PF01738.13 GAP90308.1 - 0.075 12.2 0.0 1.5 8.0 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Lipase_3 PF01764.20 GAP90308.1 - 0.16 11.5 0.1 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Dus PF01207.12 GAP90309.1 - 2.6e-06 26.5 0.0 3.2e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Pkinase PF00069.20 GAP90311.1 - 8.6e-66 221.7 0.0 1.4e-65 221.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP90311.1 - 8.8e-31 106.9 0.0 1.8e-30 105.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 GAP90311.1 - 8e-11 41.9 0.0 2.9e-08 33.7 0.1 2.8 2 0 0 2 2 2 1 FHA domain Kdo PF06293.9 GAP90311.1 - 0.0009 18.3 0.3 0.0017 17.4 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 GAP90311.1 - 0.0015 17.5 0.0 0.0041 16.1 0.0 1.6 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 GAP90311.1 - 0.012 14.9 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 GAP90311.1 - 0.048 13.3 4.9 0.092 12.4 0.2 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family CAP_N PF01213.14 GAP90312.1 - 0.77 8.9 23.0 0.89 8.7 3.5 2.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 GAP90312.1 - 6.2 6.1 25.4 3.4 6.9 4.9 3.1 2 0 0 2 2 2 0 Mitochondrial fission regulator STT3 PF02516.9 GAP90313.1 - 8.1e-131 437.3 38.3 1.3e-125 420.1 25.3 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Dpy19 PF10034.4 GAP90313.1 - 0.0072 14.5 0.1 0.02 13.0 0.0 1.6 1 1 0 1 1 1 1 Q-cell neuroblast polarisation ATP-synt_E PF05680.7 GAP90314.1 - 1.4e-23 82.6 0.4 1.5e-23 82.5 0.2 1.1 1 0 0 1 1 1 1 ATP synthase E chain DUF3186 PF11382.3 GAP90314.1 - 0.052 12.6 0.0 0.054 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) WD40 PF00400.27 GAP90315.1 - 2e-15 56.0 8.9 7.1e-06 25.7 0.1 6.7 7 1 0 7 7 7 4 WD domain, G-beta repeat Proteasome PF00227.21 GAP90317.1 - 1.5e-46 158.0 0.0 2e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 GAP90317.1 - 6.3e-15 54.1 0.5 1.2e-14 53.2 0.3 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Trehalase PF01204.13 GAP90318.1 - 3.2e-117 392.3 3.7 8.6e-108 361.1 0.1 2.0 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.9 GAP90318.1 - 0.00039 19.2 0.0 0.00072 18.3 0.0 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Acetyltransf_3 PF13302.1 GAP90319.1 - 1.5e-16 60.8 0.0 2.8e-16 59.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAP90319.1 - 0.00082 19.3 0.0 0.002 18.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAP90319.1 - 0.037 13.9 0.0 0.077 12.8 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAP90319.1 - 0.097 12.7 0.0 0.44 10.6 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family COPIIcoated_ERV PF07970.7 GAP90320.1 - 5.8e-73 245.1 0.1 1.8e-71 240.3 0.1 2.1 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 GAP90320.1 - 1.1e-34 118.2 0.0 4e-34 116.4 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sel1 PF08238.7 GAP90321.1 - 8e-13 48.5 6.0 0.0054 17.3 0.0 4.2 4 0 0 4 4 4 3 Sel1 repeat Beta_elim_lyase PF01212.16 GAP90322.1 - 1.4e-65 221.3 0.0 1.7e-65 221.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 GAP90322.1 - 0.0013 17.5 0.2 0.0024 16.6 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 GAP90322.1 - 0.0031 16.5 0.0 0.0046 15.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 GAP90322.1 - 0.078 11.2 0.0 0.13 10.5 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.15 GAP90322.1 - 0.18 10.3 0.0 0.26 9.8 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Glyco_transf_17 PF04724.8 GAP90323.1 - 3.9e-51 174.1 0.2 5.1e-51 173.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 17 AIRC PF00731.15 GAP90325.1 - 6e-59 197.6 1.4 1.1e-58 196.7 1.0 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 GAP90325.1 - 1.8e-48 164.1 0.0 2.9e-48 163.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 GAP90325.1 - 7.4e-10 38.8 0.0 1.5e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 GAP90325.1 - 6.8e-06 25.6 0.0 1.8e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.12 GAP90325.1 - 0.002 17.4 0.0 0.0049 16.1 0.0 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain XdhC_C PF13478.1 GAP90325.1 - 0.0024 18.1 0.1 0.31 11.3 0.0 2.5 2 0 0 2 2 2 1 XdhC Rossmann domain ATPgrasp_Ter PF15632.1 GAP90325.1 - 0.0078 14.9 0.0 0.02 13.6 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon PrpR_N PF06506.6 GAP90325.1 - 0.041 13.2 0.2 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 Propionate catabolism activator 2-Hacid_dh_C PF02826.14 GAP90325.1 - 0.065 12.3 0.0 0.14 11.2 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ribosomal_S8 PF00410.14 GAP90326.1 - 3.5e-23 81.8 0.0 4.6e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Prefoldin PF02996.12 GAP90327.1 - 2.6e-25 88.3 0.0 3.3e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Sec2p PF06428.6 GAP90327.1 - 0.003 17.3 2.5 0.083 12.7 0.2 2.1 2 0 0 2 2 2 2 GDP/GTP exchange factor Sec2p Prefoldin_2 PF01920.15 GAP90327.1 - 0.006 16.3 0.4 3.2 7.5 0.1 2.1 2 0 0 2 2 2 2 Prefoldin subunit DUF1192 PF06698.6 GAP90327.1 - 0.087 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) AAA PF00004.24 GAP90329.1 - 2e-14 53.9 0.0 3.4e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAP90329.1 - 4.5e-10 39.8 0.0 5.4e-09 36.3 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAP90329.1 - 8.2e-07 29.2 0.0 1.8e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain BAH PF01426.13 GAP90329.1 - 2e-06 27.5 0.0 4.3e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 BAH domain AAA_17 PF13207.1 GAP90329.1 - 0.00091 20.0 0.0 0.0041 17.9 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 GAP90329.1 - 0.0041 16.8 2.4 0.0053 16.4 0.1 2.4 2 0 0 2 2 1 1 Part of AAA domain AAA_18 PF13238.1 GAP90329.1 - 0.0044 17.3 0.0 0.014 15.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 GAP90329.1 - 0.013 15.1 0.2 0.031 13.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 GAP90329.1 - 0.037 13.7 0.0 0.4 10.3 0.0 2.1 1 1 0 1 1 1 0 Archaeal ATPase DUF2075 PF09848.4 GAP90329.1 - 0.038 12.9 0.0 0.057 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_32 PF13654.1 GAP90329.1 - 0.041 12.5 0.0 0.063 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Zot PF05707.7 GAP90329.1 - 0.045 13.2 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) NACHT PF05729.7 GAP90329.1 - 0.045 13.4 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 GAP90329.1 - 0.069 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 GAP90329.1 - 0.082 12.5 0.0 1.1 8.8 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 GAP90329.1 - 0.14 12.3 0.3 1 9.5 0.0 2.6 4 0 0 4 4 2 0 RNA helicase WD40 PF00400.27 GAP90330.1 - 1.5e-53 176.8 15.1 7.2e-10 38.3 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 GAP90330.1 - 0.004 15.3 4.1 2.9 5.9 0.0 4.1 1 1 3 4 4 4 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 GAP90330.1 - 0.0092 15.4 0.3 5.5 6.3 0.0 2.6 2 1 0 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 GAP90330.1 - 0.08 11.6 0.0 4.7 5.8 0.0 2.9 2 1 0 3 3 3 0 Nup133 N terminal like Ank_2 PF12796.2 GAP90331.1 - 4.2e-41 139.1 0.1 6.6e-15 55.2 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAP90331.1 - 3.5e-37 124.3 0.8 1.8e-06 27.4 0.0 6.3 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 GAP90331.1 - 6.8e-37 124.6 2.1 6.5e-13 48.4 0.1 4.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAP90331.1 - 1.9e-31 107.8 0.6 3.9e-09 36.7 0.0 4.7 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP90331.1 - 2.1e-30 101.7 0.0 0.00027 20.8 0.0 6.5 7 0 0 7 7 7 6 Ankyrin repeat Glyoxalase_4 PF13669.1 GAP90331.1 - 0.0016 18.4 0.0 0.011 15.7 0.0 2.0 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TMF_TATA_bd PF12325.3 GAP90332.1 - 2.2e-38 130.6 8.9 2.2e-38 130.6 6.2 7.1 3 1 3 6 6 6 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 GAP90332.1 - 1.4e-15 56.8 13.7 1.4e-15 56.8 9.5 8.7 6 3 3 9 9 9 2 TATA element modulatory factor 1 DNA binding Ceramidase PF05875.7 GAP90333.1 - 7.9e-94 313.6 13.7 9e-94 313.4 9.5 1.0 1 0 0 1 1 1 1 Ceramidase DUF788 PF05620.6 GAP90333.1 - 0.022 14.6 0.5 0.055 13.3 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF788) Protocadherin PF08374.6 GAP90334.1 - 0.77 9.3 0.0 0.77 9.3 0.0 3.9 2 1 2 4 4 4 0 Protocadherin Mito_carr PF00153.22 GAP90335.1 - 2.5e-56 187.3 3.1 5.7e-20 70.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Dor1 PF04124.7 GAP90336.1 - 4.5e-56 189.7 0.1 1.5e-47 161.7 0.3 2.6 1 1 1 2 2 2 2 Dor1-like family Sec5 PF15469.1 GAP90336.1 - 0.039 13.6 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec5 TRAM_LAG1_CLN8 PF03798.11 GAP90337.1 - 2.7e-48 164.1 13.9 4.4e-48 163.4 9.6 1.3 1 0 0 1 1 1 1 TLC domain SHD1 PF03983.7 GAP90338.1 - 2.5e-36 123.1 0.0 4.9e-36 122.2 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.23 GAP90338.1 - 8.2e-35 117.9 6.4 8.1e-13 47.5 0.1 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 GAP90338.1 - 5.5e-34 115.5 8.9 8.1e-13 47.7 0.1 4.1 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 GAP90338.1 - 9.8e-22 76.2 0.4 4.8e-09 35.5 0.0 4.4 4 0 0 4 4 4 3 Variant SH3 domain SH3_3 PF08239.6 GAP90338.1 - 3.1e-07 30.4 2.5 0.006 16.7 0.6 3.4 3 0 0 3 3 3 2 Bacterial SH3 domain A_deaminase PF00962.17 GAP90339.1 - 3.9e-113 377.7 0.1 5.3e-113 377.2 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF1556 PF07590.6 GAP90340.1 - 0.0046 17.1 2.2 0.0075 16.4 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1556) Ad_cyc_g-alpha PF08509.6 GAP90340.1 - 2.4 7.5 5.9 13 5.2 0.0 2.5 2 1 0 2 2 2 0 Adenylate cyclase G-alpha binding domain Homeobox PF00046.24 GAP90341.1 - 0.024 14.2 1.2 0.024 14.2 0.8 3.1 3 0 0 3 3 3 0 Homeobox domain DUF3584 PF12128.3 GAP90341.1 - 0.54 7.5 67.3 0.012 13.0 33.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Bacillus_HBL PF05791.6 GAP90341.1 - 1.6 8.0 31.3 0.51 9.6 2.0 4.9 2 1 2 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) Spc7 PF08317.6 GAP90342.1 - 1.1 7.8 49.7 0.44 9.1 4.4 5.0 2 1 3 5 5 5 0 Spc7 kinetochore protein DUF3552 PF12072.3 GAP90342.1 - 1.6 7.8 59.6 0.44 9.7 7.3 4.7 1 1 3 4 4 4 0 Domain of unknown function (DUF3552) DUF2782 PF11191.3 GAP90343.1 - 0.85 9.6 4.4 3.4 7.7 3.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) Cu-oxidase_2 PF07731.9 GAP90347.1 - 4.5e-40 136.3 2.0 4.5e-40 136.3 1.4 2.8 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 GAP90347.1 - 1.3e-38 131.3 3.3 1.3e-38 131.3 2.3 2.9 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.17 GAP90347.1 - 4.2e-37 127.5 1.4 3.3e-36 124.5 0.3 2.6 2 0 0 2 2 2 1 Multicopper oxidase Terminase_4 PF05119.7 GAP90347.1 - 0.16 12.1 0.1 0.28 11.3 0.1 1.3 1 0 0 1 1 1 0 Phage terminase, small subunit zf-C2HC5 PF06221.8 GAP90348.1 - 4.9e-22 77.4 4.2 7.4e-22 76.8 2.9 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Trehalase PF01204.13 GAP90349.1 - 0.0061 15.2 0.1 0.019 13.6 0.0 1.7 2 0 0 2 2 2 1 Trehalase Hydrolase PF00702.21 GAP90350.1 - 3.5e-23 83.1 0.0 1.3e-22 81.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAP90350.1 - 7.3e-21 75.2 0.0 1.4e-20 74.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 GAP90350.1 - 9.8e-21 73.8 0.0 2.8e-20 72.3 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 GAP90350.1 - 0.00016 21.5 0.0 0.00051 19.9 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAP90350.1 - 0.0032 17.0 0.1 0.039 13.5 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Filament PF00038.16 GAP90351.1 - 9.8e-07 28.5 46.6 9.8e-07 28.5 32.3 7.4 1 1 6 8 8 8 3 Intermediate filament protein Myosin_tail_1 PF01576.14 GAP90351.1 - 0.0009 17.1 185.5 0.18 9.4 60.5 4.0 1 1 0 2 2 2 2 Myosin tail WEMBL PF05701.6 GAP90351.1 - 0.00097 17.7 214.2 0.096 11.1 23.9 6.5 1 1 4 5 5 4 4 Weak chloroplast movement under blue light DUF4472 PF14739.1 GAP90351.1 - 0.0015 18.9 4.6 0.0015 18.9 3.2 11.4 1 1 10 12 12 11 1 Domain of unknown function (DUF4472) Nup54 PF13874.1 GAP90351.1 - 0.0073 15.9 7.2 0.0073 15.9 5.0 9.6 2 1 9 11 11 10 4 Nucleoporin complex subunit 54 SlyX PF04102.7 GAP90351.1 - 0.02 15.2 6.2 0.02 15.2 4.3 12.1 6 4 5 11 11 11 0 SlyX IncA PF04156.9 GAP90351.1 - 0.023 14.3 176.5 0.33 10.5 16.8 8.3 1 1 6 7 7 7 0 IncA protein DUF869 PF05911.6 GAP90351.1 - 0.15 10.2 156.8 0.2 9.8 15.1 6.0 1 1 5 6 6 6 0 Plant protein of unknown function (DUF869) AAA_13 PF13166.1 GAP90351.1 - 0.21 10.0 145.9 0.17 10.3 25.7 5.4 2 2 3 5 5 5 0 AAA domain GAS PF13851.1 GAP90351.1 - 0.69 9.0 157.3 0.13 11.4 10.0 8.6 1 1 8 9 9 9 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.6 GAP90351.1 - 1.4 8.6 164.3 0.15 11.8 12.1 8.0 1 1 5 6 6 5 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 GAP90351.1 - 1.4 7.8 184.2 0.073 12.0 14.2 8.4 1 1 6 7 7 7 0 Autophagy protein Apg6 MscS_porin PF12795.2 GAP90351.1 - 1.5 8.0 184.4 0.071 12.4 8.4 8.2 1 1 6 8 8 8 0 Mechanosensitive ion channel porin domain CENP-F_leu_zip PF10473.4 GAP90351.1 - 2.9 7.7 177.9 0.07 12.9 8.5 8.9 1 1 6 8 8 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LVIVD PF08309.6 GAP90352.1 - 4.6e-08 31.9 1.0 0.4 9.7 0.0 4.5 4 0 0 4 4 4 3 LVIVD repeat Beta_propel PF09826.4 GAP90352.1 - 0.078 11.3 0.1 1.9 6.7 0.1 2.6 2 1 0 2 2 2 0 Beta propeller domain UPF0052 PF01933.13 GAP90353.1 - 1.2e-45 156.1 0.0 1.8e-45 155.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Ldh_1_N PF00056.18 GAP90354.1 - 4e-44 149.8 0.0 7.3e-44 149.0 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 GAP90354.1 - 6e-42 143.3 0.0 9.4e-42 142.6 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 GAP90354.1 - 1.1e-05 24.3 0.0 1.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 GAP90354.1 - 0.038 14.2 0.2 0.17 12.2 0.0 2.1 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 GAP90354.1 - 0.053 13.5 0.3 0.18 11.8 0.2 1.9 1 1 0 1 1 1 0 NADH(P)-binding YL1_C PF08265.6 GAP90355.1 - 9.3e-14 50.6 0.0 1.4e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DUF3580 PF12117.3 GAP90355.1 - 0.0052 16.7 0.3 0.0082 16.0 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3580) DUF959 PF06121.9 GAP90355.1 - 0.0076 15.9 3.6 0.011 15.4 2.5 1.3 1 1 0 1 1 1 1 Domain of Unknown Function (DUF959) DASH_Dad4 PF08650.5 GAP90356.1 - 2.3e-28 97.8 7.5 2.5e-28 97.7 5.2 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.5 GAP90356.1 - 0.0074 15.9 3.8 0.009 15.6 2.7 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 GM_CSF PF01109.12 GAP90356.1 - 0.022 14.7 0.5 0.025 14.5 0.3 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor Pecanex_C PF05041.10 GAP90356.1 - 0.023 13.7 0.3 0.024 13.6 0.2 1.0 1 0 0 1 1 1 0 Pecanex protein (C-terminus) DUF3221 PF11518.3 GAP90356.1 - 0.068 12.8 0.6 0.079 12.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3221) Actin PF00022.14 GAP90357.1 - 6e-51 173.0 0.0 1.4e-30 106.0 0.0 2.1 2 0 0 2 2 2 2 Actin bZIP_1 PF00170.16 GAP90358.1 - 5e-08 32.7 8.0 1.2e-07 31.5 5.5 1.7 1 1 0 1 1 1 1 bZIP transcription factor Peptidase_S64 PF08192.6 GAP90358.1 - 0.0038 15.6 2.3 0.0045 15.3 1.6 1.0 1 0 0 1 1 1 1 Peptidase family S64 Leu_zip PF15294.1 GAP90358.1 - 0.0062 15.6 1.1 0.009 15.1 0.8 1.1 1 0 0 1 1 1 1 Leucine zipper Adeno_PIX PF03955.9 GAP90358.1 - 0.05 14.1 5.8 0.097 13.1 0.7 2.6 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF4364 PF14277.1 GAP90358.1 - 0.052 13.1 0.2 0.08 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) dsrm PF00035.20 GAP90358.1 - 0.09 13.3 0.3 0.25 11.9 0.1 1.9 2 0 0 2 2 2 0 Double-stranded RNA binding motif bZIP_2 PF07716.10 GAP90358.1 - 0.62 9.9 15.3 0.21 11.4 4.5 2.6 2 1 1 3 3 3 0 Basic region leucine zipper Phage_ASH PF10554.4 GAP90359.1 - 0.03 14.6 0.2 0.042 14.1 0.1 1.5 1 1 0 1 1 1 0 Ash protein family Pterin_4a PF01329.14 GAP90360.1 - 0.0032 17.2 0.0 0.0049 16.5 0.0 1.3 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase FA_hydroxylase PF04116.8 GAP90361.1 - 1.3e-14 54.5 19.6 1.3e-14 54.5 13.6 1.9 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily NCA2 PF08637.5 GAP90362.1 - 3.1e-86 288.8 0.0 4.7e-86 288.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Ribonuclease_T2 PF00445.13 GAP90363.1 - 2.6e-44 151.1 0.1 4.1e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family RNA_pol_3_Rpc31 PF11705.3 GAP90364.1 - 3e-23 82.9 50.7 1.6e-14 54.4 3.9 2.8 1 1 1 2 2 2 2 DNA-directed RNA polymerase III subunit Rpc31 PKD_channel PF08016.7 GAP90365.1 - 1.2e-05 24.0 16.6 0.00026 19.5 11.6 2.5 2 1 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.26 GAP90365.1 - 0.001 18.3 27.5 0.054 12.7 17.3 2.7 2 1 0 2 2 2 1 Ion transport protein SnoaL PF07366.7 GAP90366.1 - 0.00015 21.3 0.0 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 GAP90366.1 - 0.001 19.4 0.4 0.0039 17.5 0.1 2.2 2 1 0 2 2 2 1 SnoaL-like domain Sugar_tr PF00083.19 GAP90367.1 - 1.8e-36 125.7 21.2 2.9e-36 125.0 14.7 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP90367.1 - 7.8e-32 110.3 46.7 2.7e-30 105.3 20.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Macro PF01661.16 GAP90368.1 - 5.6e-39 132.7 0.4 9.1e-39 132.0 0.3 1.4 1 0 0 1 1 1 1 Macro domain Sugar_tr PF00083.19 GAP90370.1 - 2.9e-47 161.2 32.6 1e-45 156.1 22.6 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP90370.1 - 4.2e-14 52.0 36.2 1.3e-11 43.8 9.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily YesK PF14150.1 GAP90370.1 - 0.0082 16.2 0.3 0.0082 16.2 0.2 3.8 3 1 1 4 4 4 1 YesK-like protein Pox_A14 PF05767.7 GAP90370.1 - 2.9 7.9 0.0 2.9 7.9 0.0 3.4 3 1 1 4 4 4 0 Poxvirus virion envelope protein A14 FAD_binding_3 PF01494.14 GAP90371.1 - 3.8e-07 29.4 0.1 7.1e-06 25.2 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain adh_short PF00106.20 GAP90372.1 - 2.7e-12 46.9 0.2 5e-12 46.0 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase DUF1688 PF07958.6 GAP90373.1 - 0.035 12.6 0.0 0.039 12.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1688) MCR_alpha_N PF02745.10 GAP90373.1 - 0.074 12.2 0.0 0.088 11.9 0.0 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, N-terminal domain CorA PF01544.13 GAP90374.1 - 1.7e-05 24.0 0.5 3.1e-05 23.1 0.4 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein EMP70 PF02990.11 GAP90374.1 - 6.6 5.0 6.8 0.16 10.3 0.3 1.4 2 0 0 2 2 2 0 Endomembrane protein 70 Pkinase PF00069.20 GAP90375.1 - 2e-15 56.6 0.0 3.9e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 GAP90375.1 - 0.0087 15.6 0.1 0.057 12.9 0.0 2.3 2 0 0 2 2 2 1 Choline/ethanolamine kinase SIR2 PF02146.12 GAP90376.1 - 1.2e-30 106.6 0.0 6.7e-10 38.9 0.0 3.3 3 0 0 3 3 3 3 Sir2 family E3_UbLigase_R4 PF13764.1 GAP90376.1 - 0.3 8.9 0.2 0.46 8.3 0.1 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 ABC_tran PF00005.22 GAP90377.1 - 1.9e-45 154.5 0.1 1.5e-23 83.5 0.0 3.4 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 GAP90377.1 - 3.5e-17 63.2 0.0 0.0007 19.6 0.0 4.5 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 GAP90377.1 - 1.1e-15 57.5 0.4 6.3e-05 22.2 0.0 3.9 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 GAP90377.1 - 2.1e-10 41.2 1.7 8e-05 23.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 GAP90377.1 - 6.3e-10 38.4 0.0 0.0015 18.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 GAP90377.1 - 8.4e-08 33.0 0.0 0.0072 17.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAP90377.1 - 1.4e-07 31.7 0.0 0.0016 18.5 0.0 3.2 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 GAP90377.1 - 1.4e-07 30.8 0.0 0.00091 18.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_28 PF13521.1 GAP90377.1 - 5.1e-07 29.8 0.0 0.022 14.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 GAP90377.1 - 5.1e-07 29.6 0.0 0.0053 16.6 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 GAP90377.1 - 2.3e-06 27.2 0.1 0.26 10.7 0.0 3.6 4 0 0 4 4 3 2 AAA-like domain AAA_33 PF13671.1 GAP90377.1 - 3.6e-06 26.8 0.0 0.15 11.9 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 GAP90377.1 - 5.7e-06 25.6 4.8 0.17 10.8 0.0 4.9 3 2 1 5 5 5 1 AAA ATPase domain AAA_18 PF13238.1 GAP90377.1 - 6.9e-06 26.3 0.4 0.17 12.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain Miro PF08477.8 GAP90377.1 - 6.9e-06 26.5 0.0 0.047 14.1 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein Dynamin_N PF00350.18 GAP90377.1 - 1.3e-05 25.1 0.0 0.0022 17.8 0.0 2.8 2 0 0 2 2 2 1 Dynamin family SbcCD_C PF13558.1 GAP90377.1 - 1.7e-05 24.6 0.0 0.039 13.8 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MobB PF03205.9 GAP90377.1 - 2.6e-05 23.9 0.0 0.34 10.5 0.0 2.9 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 GAP90377.1 - 2.9e-05 24.2 0.0 0.48 10.6 0.0 4.2 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 GAP90377.1 - 7.2e-05 21.7 0.7 0.4 9.4 0.0 2.9 3 0 0 3 3 3 2 ArgK protein PduV-EutP PF10662.4 GAP90377.1 - 7.6e-05 22.2 0.1 0.1 12.0 0.0 2.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 GAP90377.1 - 9.7e-05 22.5 0.0 0.78 9.9 0.0 2.8 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.7 GAP90377.1 - 0.00016 21.3 0.0 0.07 12.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 GAP90377.1 - 0.0002 21.4 0.0 0.88 9.5 0.0 3.8 4 0 0 4 4 4 1 AAA ATPase domain AAA_14 PF13173.1 GAP90377.1 - 0.00027 20.8 0.0 1.7 8.5 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_13 PF13166.1 GAP90377.1 - 0.00027 19.5 1.6 1.4 7.2 0.0 3.8 4 1 0 4 4 4 2 AAA domain Arch_ATPase PF01637.13 GAP90377.1 - 0.00059 19.6 0.0 1.3 8.6 0.0 2.8 2 0 0 2 2 2 2 Archaeal ATPase DUF87 PF01935.12 GAP90377.1 - 0.0011 18.8 0.2 0.97 9.2 0.0 3.2 3 0 0 3 3 2 1 Domain of unknown function DUF87 HEAT PF02985.17 GAP90377.1 - 0.002 18.0 0.7 16 5.9 0.1 4.4 4 0 0 4 4 3 0 HEAT repeat cobW PF02492.14 GAP90377.1 - 0.0023 17.4 0.2 2.6 7.4 0.0 3.2 4 0 0 4 4 3 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 GAP90377.1 - 0.0024 16.9 0.6 0.99 8.3 0.0 3.2 3 0 0 3 3 3 1 Septin AAA_30 PF13604.1 GAP90377.1 - 0.0042 16.7 0.0 4.9 6.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain Adaptin_N PF01602.15 GAP90377.1 - 0.0042 15.4 1.5 0.017 13.4 0.6 1.6 1 1 0 1 1 1 1 Adaptin N terminal region MutS_V PF00488.16 GAP90377.1 - 0.0066 15.8 0.1 0.6 9.4 0.0 2.5 2 0 0 2 2 2 1 MutS domain V ATP-synt_ab PF00006.20 GAP90377.1 - 0.0081 15.6 0.0 0.6 9.5 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.12 GAP90377.1 - 0.017 14.6 0.1 7.9 5.9 0.0 2.8 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.1 GAP90377.1 - 0.022 14.1 0.0 6.2 6.1 0.0 3.0 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.13 GAP90377.1 - 0.028 13.8 0.1 3.8 6.9 0.0 2.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family PRK PF00485.13 GAP90377.1 - 0.037 13.5 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Mg_chelatase PF01078.16 GAP90377.1 - 0.038 13.1 0.0 3.2 6.8 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.10 GAP90377.1 - 0.04 12.5 0.0 3.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein ParcG PF10274.4 GAP90377.1 - 0.13 12.1 0.3 8.2 6.2 0.0 2.8 2 1 1 3 3 3 0 Parkin co-regulated protein HEAT_EZ PF13513.1 GAP90377.1 - 1.6 9.2 6.8 53 4.4 0.0 5.3 5 1 1 6 6 4 0 HEAT-like repeat Stc1 PF12898.2 GAP90378.1 - 0.033 14.2 1.4 0.059 13.4 1.0 1.4 1 0 0 1 1 1 0 Stc1 domain Abhydrolase_6 PF12697.2 GAP90379.1 - 3.9e-25 89.0 3.6 5.7e-25 88.5 2.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP90379.1 - 4.1e-16 59.2 0.2 9.6e-16 58.0 0.1 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP90379.1 - 1.1e-07 31.7 0.0 1.6e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 GAP90379.1 - 5.3e-06 25.1 0.0 8.3e-06 24.4 0.0 1.2 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 GAP90379.1 - 0.00033 20.4 0.0 0.00088 19.0 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase DUF3112 PF11309.3 GAP90380.1 - 1.9e-39 135.0 1.2 1.6e-34 119.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) OxoDH_E1alpha_N PF12573.3 GAP90380.1 - 0.087 12.3 0.0 0.087 12.3 0.0 2.1 2 0 0 2 2 2 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal DUF4203 PF13886.1 GAP90380.1 - 0.28 10.6 10.3 0.92 8.9 6.7 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4203) DUF1996 PF09362.5 GAP90383.1 - 5.6e-90 301.0 1.3 7.2e-90 300.7 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) tRNA-synt_1c PF00749.16 GAP90384.1 - 2.9e-78 262.6 0.0 3.8e-51 173.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 GAP90384.1 - 2.8e-30 105.2 0.0 8.7e-30 103.6 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Ribosomal_60s PF00428.14 GAP90384.1 - 0.42 11.0 11.5 1.1 9.6 7.9 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Clr5 PF14420.1 GAP90385.1 - 2.6e-18 65.6 1.9 5.2e-18 64.6 1.3 1.5 1 0 0 1 1 1 1 Clr5 domain GST_N_3 PF13417.1 GAP90386.1 - 4.4e-18 65.2 0.0 9.6e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAP90386.1 - 2e-14 53.2 0.0 3.5e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAP90386.1 - 4.3e-12 46.0 0.0 8.2e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 GAP90386.1 - 1e-05 25.3 0.0 2.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.1 GAP90386.1 - 0.00014 21.6 0.0 0.00026 20.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAP90386.1 - 0.018 15.0 0.0 0.037 14.0 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PAM2 PF07145.10 GAP90387.1 - 0.0079 15.6 0.1 0.12 11.9 0.0 2.9 2 0 0 2 2 2 1 Ataxin-2 C-terminal region APH PF01636.18 GAP90388.1 - 4.8e-18 65.7 0.0 6.9e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Got1 PF04178.7 GAP90389.1 - 1.8e-16 60.3 9.4 2.3e-16 59.9 6.5 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family YrhK PF14145.1 GAP90389.1 - 5.6 6.7 8.7 0.9 9.2 2.0 2.3 2 0 0 2 2 2 0 YrhK-like protein Profilin PF00235.14 GAP90390.1 - 5.7e-30 103.9 1.8 2.5e-20 72.7 0.3 2.1 2 0 0 2 2 2 2 Profilin Cytochrom_C_2 PF01322.15 GAP90390.1 - 0.062 13.8 0.4 0.12 12.8 0.3 1.4 1 0 0 1 1 1 0 Cytochrome C' Longin PF13774.1 GAP90392.1 - 8.3e-17 60.5 0.0 1.4e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 GAP90392.1 - 9.2e-13 47.6 0.5 1.5e-12 46.9 0.3 1.3 1 0 0 1 1 1 1 Synaptobrevin Tbf5 PF06331.7 GAP90392.1 - 0.016 14.9 0.4 0.031 14.0 0.3 1.4 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Imm43 PF15602.1 GAP90392.1 - 0.041 13.8 1.7 0.24 11.3 0.0 2.3 2 1 0 2 2 2 0 Immunity protein 43 DUF2336 PF10098.4 GAP90392.1 - 0.11 11.6 0.0 0.18 11.0 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2336) Sec63 PF02889.11 GAP90393.1 - 1.3e-154 514.1 0.0 1.4e-94 316.8 0.1 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 GAP90393.1 - 1.4e-53 180.8 0.1 3.1e-29 101.6 0.2 3.6 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP90393.1 - 8.1e-17 60.8 0.0 3.3e-07 30.0 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 GAP90393.1 - 7.1e-15 55.3 0.0 4.2e-06 26.7 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 GAP90393.1 - 2.4e-09 37.4 0.1 0.0013 18.8 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_19 PF13245.1 GAP90393.1 - 1.3e-05 24.8 0.1 0.033 13.9 0.0 3.2 3 0 0 3 3 3 2 Part of AAA domain AAA_30 PF13604.1 GAP90393.1 - 6.6e-05 22.5 0.0 0.059 12.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 GAP90393.1 - 0.017 14.5 0.0 2.2 7.6 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family IstB_IS21 PF01695.12 GAP90393.1 - 0.019 14.3 0.2 12 5.2 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_10 PF12846.2 GAP90393.1 - 0.025 14.0 0.1 17 4.6 0.0 3.8 3 1 0 4 4 4 0 AAA-like domain Zeta_toxin PF06414.7 GAP90393.1 - 0.09 11.8 0.0 5.9 5.9 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin GPI-anchored PF10342.4 GAP90394.1 - 1e-19 70.7 0.1 1e-19 70.7 0.1 2.8 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MFS_1 PF07690.11 GAP90395.1 - 9.1e-21 73.9 31.1 1.7e-19 69.7 10.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1275 PF06912.6 GAP90398.1 - 1.3e-42 145.3 17.4 1.5e-42 145.1 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF1405 PF07187.6 GAP90398.1 - 0.14 11.8 4.1 0.25 11.0 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1405) DEAD PF00270.24 GAP90399.1 - 2.5e-18 66.1 0.0 5.7e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP90399.1 - 3.3e-18 65.3 1.9 1.4e-16 60.0 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RQC PF09382.5 GAP90399.1 - 5.9e-09 35.5 0.8 1.4e-08 34.3 0.2 2.0 2 0 0 2 2 2 1 RQC domain ResIII PF04851.10 GAP90399.1 - 0.021 14.6 0.1 0.11 12.2 0.0 2.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit KAR9 PF08580.5 GAP90400.1 - 2.8e-133 445.6 0.2 2.8e-133 445.6 0.1 1.6 2 0 0 2 2 2 1 Yeast cortical protein KAR9 Syntaxin-6_N PF09177.6 GAP90400.1 - 0.05 13.9 6.1 0.38 11.1 0.6 3.8 4 0 0 4 4 4 0 Syntaxin 6, N-terminal AAA PF00004.24 GAP90402.1 - 4e-43 146.7 0.0 8.8e-43 145.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAP90402.1 - 7.5e-08 32.5 0.2 4.3e-06 26.8 0.0 3.0 2 2 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 GAP90402.1 - 1.8e-06 27.6 0.1 3.7e-05 23.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 GAP90402.1 - 2.3e-06 27.6 0.0 7.7e-06 25.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 GAP90402.1 - 2.5e-06 27.6 0.0 0.001 19.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 GAP90402.1 - 7.3e-06 25.1 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 GAP90402.1 - 0.00023 20.1 0.0 0.00058 18.8 0.0 1.7 2 0 0 2 2 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 GAP90402.1 - 0.00031 20.4 0.0 0.00075 19.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 GAP90402.1 - 0.00066 20.4 0.9 0.002 18.9 0.1 2.4 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 GAP90402.1 - 0.0013 18.6 0.0 0.0027 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 GAP90402.1 - 0.0017 17.1 0.0 0.0031 16.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 GAP90402.1 - 0.002 18.4 0.2 0.0081 16.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 GAP90402.1 - 0.0021 17.9 0.0 0.0063 16.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 GAP90402.1 - 0.0026 17.2 0.0 0.0054 16.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 GAP90402.1 - 0.003 16.7 0.0 0.0062 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 GAP90402.1 - 0.0048 17.0 0.0 0.0096 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 GAP90402.1 - 0.0052 15.9 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 GAP90402.1 - 0.0073 15.8 0.0 0.025 14.0 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 GAP90402.1 - 0.0083 15.5 0.1 0.047 13.0 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 GAP90402.1 - 0.0091 15.6 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 GAP90402.1 - 0.016 15.1 0.0 0.047 13.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain KaiC PF06745.8 GAP90402.1 - 0.019 14.0 0.2 0.11 11.5 0.0 2.4 3 0 0 3 3 3 0 KaiC AAA_24 PF13479.1 GAP90402.1 - 0.019 14.5 0.1 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 GAP90402.1 - 0.023 14.7 0.0 0.064 13.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 GAP90402.1 - 0.024 13.5 0.1 0.4 9.4 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain ResIII PF04851.10 GAP90402.1 - 0.024 14.4 0.0 0.062 13.1 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 GAP90402.1 - 0.029 14.0 0.4 0.13 11.9 0.0 2.3 2 1 0 2 2 2 0 Archaeal ATPase PhoH PF02562.11 GAP90402.1 - 0.03 13.5 0.0 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein eIF-1a PF01176.14 GAP90402.1 - 0.035 13.5 0.1 0.065 12.6 0.1 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 NACHT PF05729.7 GAP90402.1 - 0.038 13.6 0.0 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Thymidylate_kin PF02223.12 GAP90402.1 - 0.038 13.3 0.1 1.4 8.2 0.0 2.6 3 0 0 3 3 2 0 Thymidylate kinase AAA_11 PF13086.1 GAP90402.1 - 0.041 13.4 0.5 0.25 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 GAP90402.1 - 0.054 13.1 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 GAP90402.1 - 0.064 12.8 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 GAP90402.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_13 PF13166.1 GAP90402.1 - 0.26 9.6 2.7 9.1 4.5 1.5 2.2 2 0 0 2 2 2 0 AAA domain DUF4200 PF13863.1 GAP90402.1 - 0.35 10.8 8.3 0.039 13.8 2.6 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) AAA_23 PF13476.1 GAP90402.1 - 1.1 9.5 10.2 2.8 8.1 0.1 2.6 2 1 0 2 2 2 0 AAA domain SIS PF01380.17 GAP90403.1 - 1.3e-55 186.5 0.1 4.9e-30 103.8 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 GAP90403.1 - 4.1e-27 94.8 0.0 2.3e-19 69.3 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 GAP90403.1 - 1.3e-19 70.5 0.0 2.8e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 GAP90403.1 - 5.3e-11 42.3 0.0 1.1e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 GAP90403.1 - 2e-06 26.7 0.0 3.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 GAP90403.1 - 0.076 12.7 0.0 0.55 9.9 0.0 2.3 2 0 0 2 2 2 0 SIS domain Proteasome PF00227.21 GAP90404.1 - 6.5e-21 74.4 0.0 9e-21 74.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit HCNGP PF07818.8 GAP90405.1 - 3.1e-16 59.1 0.0 5.4e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 HCNGP-like protein UTRA PF07702.8 GAP90406.1 - 0.1 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 UTRA domain AAA PF00004.24 GAP90408.1 - 1.4e-18 67.3 0.0 3.5e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAP90408.1 - 1.5e-05 25.1 0.0 4.9e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAP90408.1 - 7.8e-05 23.4 0.0 7.8e-05 23.4 0.0 3.8 4 1 0 4 4 4 1 AAA domain AAA_16 PF13191.1 GAP90408.1 - 0.00025 21.1 0.3 0.0016 18.4 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 GAP90408.1 - 0.00096 18.8 0.0 0.0031 17.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 GAP90408.1 - 0.045 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 GAP90408.1 - 0.063 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain RuvB_N PF05496.7 GAP90408.1 - 0.075 12.0 0.2 0.23 10.4 0.1 1.8 1 1 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 GAP90408.1 - 0.14 12.4 0.0 0.14 12.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain NOA36 PF06524.7 GAP90408.1 - 3.8 6.6 20.8 7.5 5.7 14.4 1.5 1 0 0 1 1 1 0 NOA36 protein MOSC_N PF03476.11 GAP90410.1 - 1.2e-18 66.9 0.0 2.4e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 GAP90410.1 - 2e-18 66.1 0.0 3.6e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.14 GAP90410.1 - 5.6e-17 61.5 0.0 1.1e-16 60.5 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V DUF554 PF04474.7 GAP90410.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF554) AAA_16 PF13191.1 GAP90411.1 - 5.7e-12 46.0 0.0 7.3e-11 42.3 0.0 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAP90411.1 - 2e-11 44.1 0.0 5.5e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 GAP90411.1 - 5.1e-10 39.6 0.0 1.3e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 GAP90411.1 - 0.0001 22.1 0.1 0.00067 19.4 0.0 2.3 2 1 0 2 2 2 1 Archaeal ATPase AAA_30 PF13604.1 GAP90411.1 - 0.00028 20.5 0.0 0.00083 18.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAP90411.1 - 0.0015 18.2 0.0 0.03 14.0 0.0 2.9 3 0 0 3 3 3 1 Part of AAA domain AAA_14 PF13173.1 GAP90411.1 - 0.0019 18.1 0.0 0.0044 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.9 GAP90411.1 - 0.0019 17.8 0.3 0.018 14.6 0.0 2.5 2 1 1 3 3 3 1 Helicase AAA_5 PF07728.9 GAP90411.1 - 0.0059 16.3 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.7 GAP90411.1 - 0.0064 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.4 GAP90411.1 - 0.0077 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Cdc6_C PF09079.6 GAP90411.1 - 0.0096 15.6 0.6 0.054 13.2 0.0 2.4 3 0 0 3 3 3 1 CDC6, C terminal RNA_helicase PF00910.17 GAP90411.1 - 0.012 15.7 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.9 GAP90411.1 - 0.013 14.5 0.2 0.047 12.6 0.0 1.8 2 1 0 2 2 2 0 KAP family P-loop domain AAA_11 PF13086.1 GAP90411.1 - 0.023 14.2 0.1 0.051 13.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 GAP90411.1 - 0.024 13.4 0.0 0.04 12.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DEAD PF00270.24 GAP90411.1 - 0.053 13.0 0.3 6 6.3 0.1 2.8 2 1 1 3 3 3 0 DEAD/DEAH box helicase DUF815 PF05673.8 GAP90411.1 - 0.092 11.6 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA12 PF10443.4 GAP90411.1 - 0.11 10.9 0.1 0.56 8.6 0.0 2.0 2 0 0 2 2 2 0 RNA12 protein Arrestin_N PF00339.24 GAP90412.1 - 1.8e-16 60.3 0.0 5.1e-16 58.8 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 GAP90412.1 - 1e-08 35.3 0.0 0.00014 21.9 0.0 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.10 GAP90412.1 - 0.13 10.9 0.0 0.81 8.4 0.0 2.0 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 26 zf-RING_2 PF13639.1 GAP90413.1 - 2.2e-08 33.8 1.1 2.1e-07 30.6 0.1 3.0 2 1 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 GAP90413.1 - 3.7e-06 26.9 0.3 0.00045 20.2 0.1 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 GAP90413.1 - 0.00093 18.8 3.3 0.0089 15.7 0.0 3.1 3 0 0 3 3 3 1 RING-type zinc-finger Ribosomal_60s PF00428.14 GAP90413.1 - 0.0013 19.1 5.2 0.0022 18.3 3.6 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein zf-C3HC4_2 PF13923.1 GAP90413.1 - 0.003 17.5 0.0 0.003 17.5 0.0 4.0 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAP90413.1 - 0.053 13.1 0.7 0.053 13.1 0.5 4.0 3 2 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAP90413.1 - 0.058 13.0 0.0 0.058 13.0 0.0 3.1 3 2 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 GAP90413.1 - 1.1 9.2 9.7 2.2 8.3 1.1 3.4 3 1 0 3 3 3 0 FANCL C-terminal domain Prok-RING_4 PF14447.1 GAP90413.1 - 3.3 7.3 8.6 20 4.8 0.0 3.6 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.1 GAP90414.1 - 1.2e-10 41.0 4.5 1.2e-10 41.0 3.1 1.7 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.2 GAP90414.1 - 6.9e-08 32.4 2.9 1.4e-07 31.5 2.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 GAP90414.1 - 1e-07 31.5 4.0 2.5e-07 30.2 2.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAP90414.1 - 1.6e-06 27.9 3.8 1.6e-06 27.9 2.7 2.1 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAP90414.1 - 2.2e-06 27.2 3.6 4.8e-06 26.2 2.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 GAP90414.1 - 2.9e-06 26.8 2.2 2.9e-06 26.8 1.6 2.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAP90414.1 - 3.4e-05 23.4 0.9 3.4e-05 23.4 0.6 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 GAP90414.1 - 7.7e-05 22.4 1.4 0.00025 20.8 1.0 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 GAP90414.1 - 0.022 14.6 2.1 0.041 13.7 1.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Pellino PF04710.9 GAP90414.1 - 0.18 10.3 1.1 0.26 9.8 0.8 1.1 1 0 0 1 1 1 0 Pellino Rtf2 PF04641.7 GAP90414.1 - 0.2 10.8 0.4 0.32 10.1 0.3 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger zf-Nse PF11789.3 GAP90414.1 - 0.26 10.8 1.8 0.5 9.9 1.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.1 GAP90414.1 - 4.7 6.8 8.5 3.9 7.0 3.6 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 ThiF PF00899.16 GAP90416.1 - 9.9e-40 135.5 0.0 1.7e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 GAP90416.1 - 4.3e-21 74.2 0.9 5e-20 70.8 0.6 2.3 1 1 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 GAP90416.1 - 6.3e-14 52.2 0.0 1.1e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 GAP90416.1 - 0.0057 16.7 0.0 0.1 12.6 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase MscS_porin PF12795.2 GAP90416.1 - 0.05 12.9 1.0 0.073 12.3 0.7 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Prefoldin PF02996.12 GAP90416.1 - 0.15 11.7 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Prefoldin subunit FAD_binding_3 PF01494.14 GAP90416.1 - 0.3 10.0 1.6 0.43 9.5 1.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pam17 PF08566.5 GAP90417.1 - 2.4e-58 196.6 0.0 2.8e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Glyco_hydro_2 PF00703.16 GAP90418.1 - 6.3e-13 49.1 0.7 6.3e-13 49.1 0.5 3.4 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 GAP90418.1 - 3.3e-08 33.2 0.2 4.7e-07 29.5 0.1 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 GAP90418.1 - 0.0091 14.9 0.4 0.017 14.0 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain BNR_2 PF13088.1 GAP90419.1 - 2.8e-08 33.3 0.1 1.9e-05 24.1 0.0 2.4 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 GAP90419.1 - 0.025 14.3 10.8 0.17 11.7 0.1 3.8 4 0 0 4 4 4 0 BNR/Asp-box repeat NPCC PF08058.6 GAP90420.1 - 0.063 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Nuclear pore complex component ALIX_LYPXL_bnd PF13949.1 GAP90421.1 - 0.11 11.3 0.1 0.11 11.3 0.1 2.2 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV DivIC PF04977.10 GAP90421.1 - 1.3 8.5 4.7 2.5 7.6 0.9 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF4470 PF14737.1 GAP90422.1 - 1e-16 60.4 0.0 2.6e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) RNase_H2_suC PF08615.6 GAP90423.1 - 4.4e-28 97.8 0.0 5.2e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF1902 PF08972.6 GAP90423.1 - 0.11 12.0 0.8 0.22 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) MOZ_SAS PF01853.13 GAP90424.1 - 5.2e-85 283.4 0.3 7.3e-85 282.9 0.2 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 GAP90424.1 - 5.9e-18 64.3 0.0 2.5e-17 62.3 0.0 2.1 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 GAP90424.1 - 0.053 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAP90424.1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain SpoIIIAH PF12685.2 GAP90424.1 - 0.35 10.3 4.9 0.66 9.4 3.4 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein Aminotran_1_2 PF00155.16 GAP90425.1 - 3.8e-11 42.5 0.0 5.6e-07 28.8 0.0 3.5 4 0 0 4 4 4 2 Aminotransferase class I and II Aminotran_MocR PF12897.2 GAP90425.1 - 0.016 13.8 0.0 0.028 12.9 0.0 1.3 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase DUF1237 PF06824.6 GAP90426.1 - 4.7e-178 592.1 0.0 6e-178 591.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Pantoate_ligase PF02569.10 GAP90427.1 - 4.9e-71 238.7 0.0 8.8e-71 237.9 0.0 1.4 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase DUF3883 PF13020.1 GAP90428.1 - 0.12 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3883) SNF2_N PF00176.18 GAP90429.1 - 2.2e-70 236.7 0.3 4.1e-70 235.9 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAP90429.1 - 2.3e-17 62.6 0.4 8.4e-17 60.8 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAP90429.1 - 3.9e-07 30.0 0.0 1.7e-06 28.0 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Sld5 PF05916.6 GAP90430.1 - 7.1e-24 84.1 0.0 1e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein VRP1 PF03538.9 GAP90432.1 - 2e-06 27.0 0.0 7.5e-06 25.2 0.0 2.0 2 0 0 2 2 2 1 Salmonella virulence plasmid 28.1kDa A protein SpvB PF03534.8 GAP90434.1 - 1.1e-76 257.6 0.0 2.8e-76 256.3 0.0 1.7 1 0 0 1 1 1 1 Salmonella virulence plasmid 65kDa B protein TcdB_toxin_midN PF12256.3 GAP90434.1 - 2.7e-35 121.3 7.1 8e-30 103.5 0.0 6.4 6 1 1 7 7 7 3 Insecticide toxin TcdB middle/N-terminal region TcdB_toxin_midC PF12255.3 GAP90434.1 - 6.3e-21 74.5 0.1 1.5e-20 73.3 0.1 1.6 1 0 0 1 1 1 1 Insecticide toxin TcdB middle/C-terminal region VCBS PF13517.1 GAP90434.1 - 8.8e-09 35.6 16.9 0.018 15.3 1.1 5.4 4 1 1 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF2380 PF09533.5 GAP90434.1 - 1.7e-07 30.8 0.0 3.8e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Predicted lipoprotein of unknown function (DUF2380) RHS_repeat PF05593.9 GAP90434.1 - 3.4e-05 23.9 24.1 15 5.9 0.1 11.8 10 1 0 10 10 10 2 RHS Repeat FG-GAP PF01839.18 GAP90434.1 - 0.0033 17.0 7.4 0.1 12.2 0.2 4.2 4 0 0 4 4 4 1 FG-GAP repeat Glyco_hydro_2_N PF02837.13 GAP90435.1 - 5.6e-33 113.8 0.1 2e-32 112.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 GAP90435.1 - 1.8e-31 109.1 0.0 6.1e-31 107.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 GAP90435.1 - 7.5e-14 52.1 0.2 1.9e-13 50.7 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 GAP90435.1 - 0.00034 20.8 0.1 0.017 15.3 0.0 2.9 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Cellulase-like PF12876.2 GAP90435.1 - 0.012 16.0 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 0 Sugar-binding cellulase-like Aminotran_1_2 PF00155.16 GAP90436.1 - 1.4e-63 215.0 0.0 1.7e-63 214.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II p450 PF00067.17 GAP90439.1 - 1.7e-65 221.4 0.0 2.2e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SNF2_N PF00176.18 GAP90442.1 - 2.3e-72 243.3 0.1 5.4e-72 242.1 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain DEAD PF00270.24 GAP90442.1 - 4.2e-12 45.8 0.0 4.3e-11 42.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP90442.1 - 8.6e-11 41.5 0.0 1.9e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 GAP90442.1 - 0.00028 20.6 5.7 0.00028 20.6 3.9 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 GAP90442.1 - 0.00048 19.7 5.5 0.0013 18.3 3.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAP90442.1 - 0.0094 15.6 6.0 0.021 14.5 4.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 GAP90442.1 - 0.032 13.9 5.2 0.1 12.2 3.6 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-TFIIB PF13453.1 GAP90442.1 - 0.17 11.1 2.3 0.47 9.6 1.6 1.8 1 0 0 1 1 1 0 Transcription factor zinc-finger zf-C3HC4_2 PF13923.1 GAP90442.1 - 0.4 10.7 5.9 1.2 9.2 4.1 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 GAP90442.1 - 5.3 6.7 7.6 11 5.6 5.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain NACHT PF05729.7 GAP90443.1 - 1.3e-06 28.1 0.0 2.8e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAP90443.1 - 2.5e-05 24.4 0.0 0.00015 21.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 GAP90443.1 - 0.00052 20.0 1.3 0.0015 18.5 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain Ank_4 PF13637.1 GAP90443.1 - 0.00062 20.1 0.0 0.02 15.4 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAP90443.1 - 0.0013 19.0 0.0 0.026 14.8 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAP90443.1 - 0.0021 18.1 0.0 0.29 11.4 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.25 GAP90443.1 - 0.0023 17.6 0.0 0.45 10.4 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat AAA PF00004.24 GAP90443.1 - 0.0024 18.0 0.0 0.0072 16.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) VirD1 PF07328.6 GAP90443.1 - 0.06 13.1 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 T-DNA border endonuclease VirD1 zf-C2H2_4 PF13894.1 GAP90443.1 - 4.8 7.7 9.0 16 6.0 0.1 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Kinesin PF00225.18 GAP90444.1 - 2e-54 184.5 0.0 4.4e-54 183.4 0.0 1.6 1 1 0 1 1 1 1 Kinesin motor domain Jnk-SapK_ap_N PF09744.4 GAP90444.1 - 0.21 11.5 6.7 0.053 13.5 1.2 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 CENP-Q PF13094.1 GAP90444.1 - 3.6 7.6 12.4 35 4.3 8.6 2.2 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Glyco_hydro_7 PF00840.15 GAP90445.1 - 2.1e-162 540.4 19.0 2.6e-162 540.1 13.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF4369 PF14289.1 GAP90445.1 - 0.021 14.8 0.5 0.26 11.3 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4369) DUF3764 PF12594.3 GAP90445.1 - 0.024 14.3 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3764) Hamartin PF04388.7 GAP90446.1 - 1.7e-33 116.2 31.2 1.7e-33 116.2 21.7 2.7 1 1 1 2 2 2 1 Hamartin protein DUF4066 PF13278.1 GAP90447.1 - 1.7e-25 89.1 0.1 1.2e-21 76.6 0.0 2.0 2 0 0 2 2 2 2 Putative amidotransferase DJ-1_PfpI PF01965.19 GAP90447.1 - 1.3e-06 27.9 0.0 2.7e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family Ribosomal_L23 PF00276.15 GAP90448.1 - 1.4e-15 57.0 0.0 2.7e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 MT-A70 PF05063.9 GAP90449.1 - 5.5e-31 107.4 0.1 7.7e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Methyltransf_26 PF13659.1 GAP90449.1 - 0.0074 16.3 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF221 PF02714.10 GAP90450.1 - 1.5e-102 342.8 28.7 8.4e-102 340.3 17.8 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 GAP90450.1 - 9e-42 142.2 0.1 9e-42 142.2 0.1 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 GAP90450.1 - 2e-17 62.8 0.0 6e-17 61.3 0.0 1.8 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 GAP90450.1 - 1.1e-09 38.6 12.6 0.001 19.5 6.5 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF4463) DUF320 PF03777.8 GAP90450.1 - 0.024 14.3 0.3 0.35 10.6 0.0 2.3 2 0 0 2 2 2 0 Small secreted domain (DUF320) EMP70 PF02990.11 GAP90451.1 - 1e-159 532.4 0.1 1.7e-159 531.6 0.1 1.4 1 0 0 1 1 1 1 Endomembrane protein 70 Mito_carr PF00153.22 GAP90452.1 - 5.1e-59 195.9 11.0 6.2e-20 70.7 0.1 4.3 4 1 0 4 4 4 3 Mitochondrial carrier protein Pex14_N PF04695.8 GAP90452.1 - 0.37 10.8 3.5 0.94 9.5 2.5 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1014 PF06244.7 GAP90453.1 - 7.7e-09 35.8 9.3 7.7e-09 35.8 6.4 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1014) HET PF06985.6 GAP90454.1 - 8.7e-29 100.4 0.0 6.2e-28 97.7 0.0 2.2 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DAGK_cat PF00781.19 GAP90455.1 - 2e-07 30.4 0.1 4.8e-07 29.2 0.1 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain ABC_tran PF00005.22 GAP90456.1 - 2.5e-45 154.1 0.9 2.8e-21 76.2 0.0 3.9 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 GAP90456.1 - 1.5e-14 54.6 2.5 0.00013 22.0 0.0 4.2 4 0 0 4 4 4 3 AAA domain AAA_29 PF13555.1 GAP90456.1 - 4.2e-10 39.0 0.4 8.7e-06 25.1 0.0 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.14 GAP90456.1 - 6.8e-09 35.2 0.3 0.021 14.0 0.1 4.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 GAP90456.1 - 2.9e-07 30.6 0.0 0.046 13.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain ABC_tran_2 PF12848.2 GAP90456.1 - 7.3e-07 28.9 3.9 7.3e-07 28.9 2.7 2.2 2 0 0 2 2 1 1 ABC transporter MMR_HSR1 PF01926.18 GAP90456.1 - 1.8e-06 27.9 0.0 0.047 13.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 GAP90456.1 - 6.3e-06 27.0 2.4 0.0024 18.6 0.0 3.2 3 1 0 3 3 2 1 AAA domain AAA_28 PF13521.1 GAP90456.1 - 6.7e-06 26.1 0.2 0.0012 18.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 GAP90456.1 - 3.4e-05 23.5 0.0 0.0055 16.3 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 GAP90456.1 - 3.8e-05 23.5 0.7 0.2 11.5 0.0 3.5 3 0 0 3 3 3 2 AAA domain MobB PF03205.9 GAP90456.1 - 5e-05 23.0 0.1 0.13 11.9 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 GAP90456.1 - 8.8e-05 22.9 0.4 0.23 11.9 0.0 2.8 3 0 0 3 3 2 2 Miro-like protein DUF258 PF03193.11 GAP90456.1 - 0.00022 20.4 0.1 0.24 10.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Dynamin_N PF00350.18 GAP90456.1 - 0.00086 19.1 3.3 0.098 12.4 0.0 3.1 3 0 0 3 3 3 1 Dynamin family AAA_23 PF13476.1 GAP90456.1 - 0.0013 19.1 12.9 0.01 16.1 0.7 3.5 3 1 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 GAP90456.1 - 0.0014 18.1 2.3 0.029 13.8 0.6 3.0 2 1 0 2 2 2 1 FtsK/SpoIIIE family AAA_16 PF13191.1 GAP90456.1 - 0.0023 17.9 13.4 0.0086 16.0 2.4 3.4 2 2 0 2 2 2 1 AAA ATPase domain AAA_15 PF13175.1 GAP90456.1 - 0.0025 16.9 1.7 0.024 13.6 0.0 3.0 4 0 0 4 4 4 1 AAA ATPase domain AAA_25 PF13481.1 GAP90456.1 - 0.0032 16.8 0.7 0.11 11.8 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA PF00004.24 GAP90456.1 - 0.0034 17.5 0.0 0.32 11.1 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 GAP90456.1 - 0.0053 16.6 0.2 0.17 11.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain ArgK PF03308.11 GAP90456.1 - 0.0062 15.3 2.0 1.7 7.3 0.1 2.4 2 0 0 2 2 2 2 ArgK protein ABC_ATPase PF09818.4 GAP90456.1 - 0.0068 15.0 0.3 0.023 13.3 0.0 2.0 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_18 PF13238.1 GAP90456.1 - 0.0085 16.3 4.7 0.2 11.9 0.0 3.4 4 0 0 4 4 3 1 AAA domain SbcCD_C PF13558.1 GAP90456.1 - 0.016 15.0 0.2 0.51 10.2 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 GAP90456.1 - 0.02 14.6 0.4 0.35 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) cobW PF02492.14 GAP90456.1 - 0.035 13.5 0.5 2 7.8 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 GAP90456.1 - 0.035 14.2 0.1 0.6 10.3 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 GAP90456.1 - 0.051 13.2 0.7 0.27 10.9 0.0 2.4 3 0 0 3 3 3 0 Archaeal ATPase AAA_19 PF13245.1 GAP90456.1 - 0.057 13.1 1.4 0.21 11.3 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain DUF815 PF05673.8 GAP90456.1 - 0.058 12.3 3.8 0.43 9.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.13 GAP90456.1 - 0.059 12.8 0.1 2 7.8 0.0 2.9 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DUF87 PF01935.12 GAP90456.1 - 0.078 12.7 0.0 0.078 12.7 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function DUF87 AAA_30 PF13604.1 GAP90456.1 - 0.083 12.4 0.0 0.083 12.4 0.0 4.5 5 1 0 5 5 5 0 AAA domain MutS_V PF00488.16 GAP90456.1 - 0.16 11.3 0.0 9.3 5.5 0.0 2.3 2 0 0 2 2 2 0 MutS domain V AAA_13 PF13166.1 GAP90456.1 - 0.18 10.1 0.0 0.18 10.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 GAP90456.1 - 0.21 11.0 0.1 0.21 11.0 0.1 3.5 3 1 0 4 4 3 0 AAA-like domain Sugar_tr PF00083.19 GAP90457.1 - 1.4e-115 386.4 30.7 1.6e-115 386.2 21.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP90457.1 - 2.5e-19 69.1 44.3 1.3e-18 66.8 25.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily SUN PF03856.8 GAP90458.1 - 4.2e-72 242.4 10.0 4.2e-72 242.4 6.9 1.8 2 0 0 2 2 2 1 Beta-glucosidase (SUN family) Pectinesterase PF01095.14 GAP90459.1 - 4.5e-55 186.3 9.1 6e-55 185.9 6.3 1.0 1 0 0 1 1 1 1 Pectinesterase Phage_T4_Ndd PF06591.6 GAP90459.1 - 0.068 12.7 0.9 1.5 8.4 0.1 2.5 1 1 2 3 3 3 0 T4-like phage nuclear disruption protein (Ndd) PCI PF01399.22 GAP90460.1 - 0.0001 22.5 0.2 0.83 10.0 0.0 2.7 2 0 0 2 2 2 2 PCI domain TPR_2 PF07719.12 GAP90460.1 - 0.029 14.2 0.0 0.096 12.6 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Thiolase_N PF00108.18 GAP90461.1 - 3.8e-91 304.7 0.1 5.9e-91 304.0 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAP90461.1 - 9.1e-38 128.4 2.0 1.7e-37 127.5 0.3 2.2 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 GAP90461.1 - 0.00019 20.9 0.3 0.00067 19.2 0.2 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain UQ_con PF00179.21 GAP90462.1 - 1.4e-51 173.6 0.0 1.6e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAP90462.1 - 8e-07 28.8 0.0 9.2e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 GAP90462.1 - 0.041 13.7 0.1 0.098 12.5 0.1 1.6 1 1 0 1 1 1 0 RWD domain Kinesin PF00225.18 GAP90463.1 - 1.7e-112 375.4 0.1 1.7e-112 375.4 0.1 2.0 3 0 0 3 3 3 1 Kinesin motor domain POTRA_2 PF08479.6 GAP90463.1 - 0.075 12.7 0.8 0.58 9.8 0.2 2.7 2 0 0 2 2 2 0 POTRA domain, ShlB-type zf-C2H2_4 PF13894.1 GAP90464.1 - 0.00078 19.6 34.6 0.084 13.2 0.0 7.6 8 0 0 8 8 8 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 GAP90464.1 - 0.081 12.8 0.5 0.87 9.5 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 GAP90464.1 - 0.47 10.8 31.6 3.2 8.2 0.6 7.1 7 0 0 7 7 7 0 Zinc finger, C2H2 type Nucleoplasmin PF03066.10 GAP90465.1 - 0.076 12.5 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 GAP90465.1 - 1.1 8.4 6.4 1.7 7.8 4.4 1.3 1 0 0 1 1 1 0 NOA36 protein DUF4611 PF15387.1 GAP90465.1 - 1.2 9.3 5.1 1.9 8.6 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) GCIP PF13324.1 GAP90465.1 - 2.7 7.1 5.0 3.5 6.7 3.4 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Choline_kinase PF01633.15 GAP90466.1 - 5.2e-53 179.7 0.0 4.7e-52 176.6 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 GAP90466.1 - 2.1e-07 30.9 0.1 6.6e-07 29.3 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family CorA PF01544.13 GAP90467.1 - 1.1e-08 34.4 0.2 3e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Acetyltransf_1 PF00583.19 GAP90468.1 - 2.8e-10 40.0 0.0 5.9e-10 39.0 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAP90468.1 - 6.5e-08 32.2 0.0 1.3e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 GAP90468.1 - 7.5e-08 32.4 0.0 1.5e-07 31.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAP90468.1 - 2.7e-05 24.2 0.0 0.0001 22.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAP90468.1 - 0.00011 22.4 0.0 0.00021 21.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAP90468.1 - 0.00089 19.1 0.2 0.007 16.2 0.1 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAP90468.1 - 0.0024 17.6 0.0 0.0059 16.4 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 GAP90468.1 - 0.0027 17.6 0.0 0.0046 16.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CFEM PF05730.6 GAP90470.1 - 0.00056 19.6 5.2 0.00099 18.8 3.6 1.4 1 0 0 1 1 1 1 CFEM domain MutS_V PF00488.16 GAP90471.1 - 3.1e-53 180.5 0.0 5e-53 179.9 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 GAP90471.1 - 4.4e-21 75.6 0.0 8e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 MutS domain III AAA_14 PF13173.1 GAP90471.1 - 0.052 13.4 0.0 0.84 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMgT PF10270.4 GAP90472.1 - 1.5e-32 112.1 0.0 1.8e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter HAD_2 PF13419.1 GAP90473.1 - 4.4e-23 82.3 0.0 5.9e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAP90473.1 - 6.1e-11 43.1 0.0 2.6e-10 41.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAP90473.1 - 2.1e-07 30.5 0.0 4.9e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 GAP90473.1 - 0.0015 18.7 0.0 0.0019 18.3 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 GAP90473.1 - 0.0019 18.0 0.0 0.0062 16.4 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Aldolase_II PF00596.16 GAP90475.1 - 1.2e-32 112.9 0.0 1.6e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Calreticulin PF00262.13 GAP90476.1 - 9.7e-160 531.1 17.8 1.3e-159 530.7 12.3 1.1 1 0 0 1 1 1 1 Calreticulin family EspB PF05802.6 GAP90476.1 - 0.1 11.4 3.6 0.16 10.8 2.5 1.2 1 0 0 1 1 1 0 Enterobacterial EspB protein Methyltransf_11 PF08241.7 GAP90477.1 - 1.4e-11 44.6 0.0 3.7e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP90477.1 - 0.00013 21.7 0.0 0.00028 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP90477.1 - 0.14 12.6 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 GAP90477.1 - 0.16 12.3 0.0 0.47 10.8 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain SUI1 PF01253.17 GAP90478.1 - 2.3e-24 84.9 0.2 5.6e-24 83.7 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.1 GAP90478.1 - 0.0016 18.3 0.1 0.0024 17.7 0.1 1.3 1 0 0 1 1 1 1 Transposon-encoded protein TnpV Nbl1_Borealin_N PF10444.4 GAP90479.1 - 2.5e-17 61.9 6.7 4.7e-17 61.0 4.6 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal VWA_2 PF13519.1 GAP90480.1 - 8.9e-15 55.2 0.1 1.6e-14 54.4 0.0 1.3 1 1 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 GAP90480.1 - 1.2e-09 38.0 0.0 1.8e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 GAP90480.1 - 2.1e-08 34.0 0.4 3.3e-08 33.4 0.3 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 GAP90480.1 - 0.00015 21.0 1.3 0.0004 19.7 0.9 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif RNA_pol_Rpb4 PF03874.11 GAP90481.1 - 7.3e-29 100.1 3.4 9.4e-29 99.8 2.4 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Spexin PF15171.1 GAP90481.1 - 0.031 14.2 0.1 0.068 13.1 0.1 1.6 1 0 0 1 1 1 0 Neuropeptide secretory protein family, NPQ, spexin PAT1 PF09770.4 GAP90482.1 - 0.8 7.8 10.7 1.2 7.2 7.4 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CPL PF08144.6 GAP90483.1 - 3.1e-18 66.0 0.0 8.7e-18 64.5 0.0 1.8 1 1 0 1 1 1 1 CPL (NUC119) domain UBN2_3 PF14244.1 GAP90483.1 - 0.11 12.1 0.8 0.28 10.7 0.6 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RWD PF05773.17 GAP90484.1 - 2.7e-20 72.3 0.0 6.1e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 RWD domain FKBP_N PF01346.13 GAP90484.1 - 4.3 7.4 7.2 0.43 10.6 0.2 2.1 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Nbs1_C PF08599.5 GAP90484.1 - 7.9 6.4 7.2 15 5.5 1.9 2.5 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 TPR_12 PF13424.1 GAP90485.1 - 4.7e-17 61.6 0.1 7.6e-08 32.1 0.1 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAP90485.1 - 3.5e-13 49.6 8.2 2e-06 28.0 1.3 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 GAP90485.1 - 9.1e-12 44.4 1.0 0.00093 18.7 0.3 4.6 3 2 3 6 6 6 3 TPR repeat TPR_14 PF13428.1 GAP90485.1 - 1.2e-10 41.0 14.9 0.033 14.8 0.7 5.6 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 GAP90485.1 - 3e-10 39.2 10.4 0.00038 20.1 0.1 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAP90485.1 - 6.5e-10 39.4 12.1 4.6e-05 23.9 3.7 4.5 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 GAP90485.1 - 2.7e-09 36.1 1.7 0.011 15.4 0.1 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAP90485.1 - 1e-08 34.3 3.5 0.0079 15.7 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAP90485.1 - 1.9e-05 24.1 0.8 0.0072 16.0 0.0 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAP90485.1 - 0.0001 22.1 8.0 0.26 11.2 0.2 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 GAP90485.1 - 0.00034 19.7 0.1 0.14 11.3 0.0 2.9 2 0 0 2 2 2 1 SHNi-TPR Apc3 PF12895.2 GAP90485.1 - 0.00084 19.4 0.0 1.5 9.0 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 GAP90485.1 - 0.0019 18.2 0.0 2.2 8.6 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAP90485.1 - 0.063 13.7 3.8 32 5.2 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 GAP90485.1 - 0.28 11.7 8.9 0.49 10.9 0.4 3.9 4 0 0 4 4 2 0 Tetratricopeptide repeat ChAPs PF09295.5 GAP90485.1 - 0.34 9.6 2.0 0.98 8.1 0.1 2.4 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) SprT-like PF10263.4 GAP90486.1 - 0.01 15.4 4.5 0.05 13.2 3.1 2.0 1 1 0 1 1 1 0 SprT-like family Peptidase_M13 PF01431.16 GAP90486.1 - 0.18 10.9 1.3 0.96 8.5 0.9 1.9 1 1 0 1 1 1 0 Peptidase family M13 DIM PF08194.7 GAP90488.1 - 0.092 12.7 0.4 0.2 11.6 0.3 1.6 1 0 0 1 1 1 0 DIM protein UPF0506 PF11703.3 GAP90488.1 - 0.64 10.0 18.1 2.6 8.0 3.7 2.5 2 0 0 2 2 2 0 UPF0506 Prokineticin PF06607.6 GAP90488.1 - 0.69 10.0 7.2 0.93 9.6 5.0 1.3 1 0 0 1 1 1 0 Prokineticin Toxin_12 PF07740.7 GAP90488.1 - 8.7 6.9 20.1 1.6 9.2 4.9 3.1 3 0 0 3 3 3 0 Ion channel inhibitory toxin Formyl_trans_N PF00551.14 GAP90490.1 - 1.8e-36 125.4 0.2 2.4e-36 124.9 0.1 1.2 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 GAP90490.1 - 1.9e-10 39.9 0.1 5.2e-10 38.5 0.0 1.8 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.1 GAP90490.1 - 0.00021 20.9 0.0 0.00054 19.6 0.0 1.6 1 0 0 1 1 1 1 ACT domain Glyco_trans_4_2 PF13477.1 GAP90490.1 - 0.12 12.1 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like Rad51 PF08423.6 GAP90492.1 - 8.9e-136 450.7 0.0 1.2e-135 450.4 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 GAP90492.1 - 2.4e-13 49.9 0.0 3.4e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 GAP90492.1 - 3.5e-07 30.2 0.2 1.1e-06 28.6 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain KaiC PF06745.8 GAP90492.1 - 9.9e-07 28.1 0.0 1.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 KaiC RecA PF00154.16 GAP90492.1 - 1.3e-06 27.7 0.0 1.7e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein DnaB_C PF03796.10 GAP90492.1 - 0.017 14.0 0.0 0.032 13.1 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 GAP90492.1 - 0.089 11.6 0.1 0.28 9.9 0.0 1.7 2 0 0 2 2 2 0 PAXNEB protein DUF4332 PF14229.1 GAP90492.1 - 0.094 12.6 0.2 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4332) Nup160 PF11715.3 GAP90493.1 - 3.4e-111 372.0 0.3 4.5e-111 371.6 0.2 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Vps26 PF03643.10 GAP90494.1 - 4.6e-131 435.6 0.8 5.4e-131 435.3 0.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 GAP90494.1 - 0.00051 19.8 0.0 1.6 8.5 0.0 3.5 1 1 1 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Ribosomal_L6 PF00347.18 GAP90495.1 - 2.4e-26 92.0 6.0 1.2e-13 51.3 1.9 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Spore_YtfJ PF09579.5 GAP90496.1 - 0.037 13.8 1.3 0.037 13.8 0.9 2.0 2 0 0 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) Glycophorin_A PF01102.13 GAP90496.1 - 0.056 13.2 1.3 0.11 12.2 0.1 2.1 2 0 0 2 2 2 0 Glycophorin A DUF1206 PF06724.6 GAP90496.1 - 0.063 13.0 4.6 0.6 9.9 1.4 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) DUF4131 PF13567.1 GAP90496.1 - 0.12 11.7 1.3 4.2 6.7 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Rieske PF00355.21 GAP90497.1 - 9.2e-11 41.1 0.0 1.4e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 GAP90497.1 - 6.5e-07 29.0 0.0 1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain V-ATPase_H_N PF03224.9 GAP90498.1 - 6e-73 245.6 0.0 8.3e-73 245.2 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 GAP90498.1 - 9.8e-40 135.1 0.1 2.7e-39 133.7 0.0 1.8 2 0 0 2 2 2 1 V-ATPase subunit H HEAT_2 PF13646.1 GAP90498.1 - 0.002 18.3 3.2 0.054 13.7 0.0 3.7 3 1 1 4 4 4 1 HEAT repeats HEAT PF02985.17 GAP90498.1 - 0.023 14.7 0.0 0.2 11.8 0.0 2.7 1 0 0 1 1 1 0 HEAT repeat G-alpha PF00503.15 GAP90498.1 - 0.04 12.6 0.0 0.069 11.8 0.0 1.4 1 1 0 1 1 1 0 G-protein alpha subunit HEAT_EZ PF13513.1 GAP90498.1 - 0.065 13.7 5.7 0.54 10.8 0.0 4.3 4 1 1 5 5 5 0 HEAT-like repeat RIX1 PF08167.7 GAP90498.1 - 0.44 10.1 3.2 14 5.3 0.0 3.5 2 1 1 4 4 4 0 rRNA processing/ribosome biogenesis Aldedh PF00171.17 GAP90499.1 - 3.5e-136 454.2 0.4 4e-136 454.0 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAP90499.1 - 0.083 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) F-box PF00646.28 GAP90500.1 - 2.3e-07 30.2 1.3 4.5e-07 29.3 0.9 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAP90500.1 - 2e-05 24.2 0.2 4.1e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like His_Phos_2 PF00328.17 GAP90501.1 - 1.1e-15 57.8 0.0 5.3e-12 45.7 0.0 2.3 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) TcpQ PF10671.4 GAP90501.1 - 0.0021 17.8 0.0 0.0052 16.6 0.0 1.6 1 0 0 1 1 1 1 Toxin co-regulated pilus biosynthesis protein Q MFS_1 PF07690.11 GAP90502.1 - 1e-23 83.6 40.2 1e-23 83.6 27.8 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP90502.1 - 4e-07 28.9 14.5 4e-07 28.9 10.1 3.2 3 1 0 3 3 3 1 Sugar (and other) transporter DUF697 PF05128.7 GAP90502.1 - 0.23 10.9 1.5 0.33 10.4 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF697) CFEM PF05730.6 GAP90503.1 - 2.3e-14 52.9 10.4 2.3e-14 52.9 7.2 1.6 2 0 0 2 2 2 1 CFEM domain Sporozoite_P67 PF05642.6 GAP90503.1 - 0.07 10.9 7.2 0.089 10.6 5.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.12 GAP90503.1 - 0.077 12.7 28.7 0.12 12.1 19.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein TEBP_beta PF07404.6 GAP90503.1 - 0.46 9.5 2.2 0.55 9.3 1.5 1.1 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) Herpes_BLLF1 PF05109.8 GAP90503.1 - 3.3 5.5 21.9 3.7 5.3 15.2 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DUF962 PF06127.6 GAP90506.1 - 1.7e-26 91.9 0.5 2.7e-26 91.2 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF962) SHS2_Rpb7-N PF03876.12 GAP90507.1 - 2.4e-15 56.4 0.0 4.1e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 GAP90507.1 - 8.6e-13 48.1 0.0 1.4e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 GAP90507.1 - 0.019 15.1 0.0 0.039 14.1 0.0 1.5 1 1 0 1 1 1 0 RNA polymerase III subunit Rpc25 Radical_SAM PF04055.16 GAP90508.1 - 0.0014 18.7 0.0 0.0056 16.8 0.0 2.0 1 1 0 1 1 1 1 Radical SAM superfamily LAM_C PF12544.3 GAP90508.1 - 0.014 15.4 0.1 0.034 14.2 0.1 1.6 1 0 0 1 1 1 0 Lysine-2,3-aminomutase BNR PF02012.15 GAP90511.1 - 1.9e-08 32.8 43.4 0.26 11.2 0.1 12.8 12 0 0 12 12 12 5 BNR/Asp-box repeat BNR_2 PF13088.1 GAP90511.1 - 7.8e-07 28.6 16.0 0.1 11.8 0.0 7.1 4 4 1 6 6 6 3 BNR repeat-like domain DUF2561 PF10812.3 GAP90511.1 - 0.021 14.4 0.1 0.036 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) SnoaL_2 PF12680.2 GAP90512.1 - 0.0096 16.3 0.0 0.03 14.7 0.0 1.9 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 GAP90512.1 - 0.043 13.3 0.0 0.12 11.9 0.0 1.8 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase AA_permease PF00324.16 GAP90513.1 - 2.7e-141 471.1 41.3 3.4e-141 470.8 28.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAP90513.1 - 5.5e-37 127.3 40.9 7.8e-37 126.8 28.3 1.2 1 0 0 1 1 1 1 Amino acid permease MRAP PF15183.1 GAP90513.1 - 0.14 11.7 5.3 4.8 6.8 1.1 3.0 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family UPF0261 PF06792.6 GAP90513.1 - 0.27 9.6 0.0 0.51 8.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) Glyco_hydro_47 PF01532.15 GAP90514.1 - 1.7e-163 544.4 0.0 2e-163 544.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF485 PF04341.7 GAP90514.1 - 0.14 11.9 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Autophagy_act_C PF03987.10 GAP90515.1 - 8.6e-14 51.4 0.3 1.6e-13 50.6 0.2 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain RRM_5 PF13893.1 GAP90516.1 - 1.4e-08 34.4 0.0 2.4e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAP90516.1 - 2.6e-08 33.3 0.0 8.7e-08 31.6 0.0 1.9 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP90516.1 - 1.1e-05 25.2 0.0 2.5e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 GAP90516.1 - 0.0042 16.8 0.7 0.0074 16.0 0.0 1.7 2 0 0 2 2 2 1 Limkain b1 Ribosomal_60s PF00428.14 GAP90516.1 - 0.0051 17.1 10.7 0.012 16.0 7.4 1.7 1 1 0 1 1 1 1 60s Acidic ribosomal protein DUF3682 PF12446.3 GAP90516.1 - 0.14 12.4 9.3 0.28 11.4 6.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) WD40 PF00400.27 GAP90517.1 - 1.9e-20 71.8 12.0 1.1e-07 31.4 0.0 6.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Rax2 PF12768.2 GAP90517.1 - 0.0075 15.5 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Abhydrolase_1 PF00561.15 GAP90518.1 - 1.1e-22 80.6 0.6 5.2e-22 78.5 0.4 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAP90518.1 - 1.5e-21 77.3 10.0 2.4e-21 76.6 7.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP90518.1 - 3.1e-09 36.7 0.1 3.3e-08 33.3 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAP90518.1 - 0.02 14.7 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase AXE1 PF05448.7 GAP90518.1 - 0.08 11.4 0.0 7.2 4.9 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) BTB PF00651.26 GAP90519.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain ADH_zinc_N PF00107.21 GAP90520.1 - 1.7e-14 53.4 0.1 1.4e-13 50.5 0.1 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAP90520.1 - 0.00023 22.0 0.1 0.0025 18.7 0.0 2.7 3 1 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP90520.1 - 0.02 14.6 0.0 0.094 12.4 0.0 2.0 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain Ferric_reduct PF01794.14 GAP90521.1 - 1.1e-21 77.2 10.6 1.1e-21 77.2 7.4 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 GAP90521.1 - 8e-17 61.5 0.0 1.1e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 GAP90521.1 - 6.2e-11 42.1 0.0 1.3e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 GAP90521.1 - 2.2e-05 24.9 0.0 4.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Bact_transglu_N PF08379.5 GAP90521.1 - 0.046 14.0 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial transglutaminase-like N-terminal region Ctr PF04145.10 GAP90522.1 - 2.7e-40 137.7 4.4 3.4e-40 137.4 3.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF457 PF04307.9 GAP90522.1 - 0.24 10.7 5.2 0.06 12.6 1.0 1.7 1 1 0 2 2 2 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) Sensor PF13796.1 GAP90522.1 - 1.6 8.3 5.4 3 7.4 0.0 2.2 2 0 0 2 2 2 0 Putative sensor tRNA-synt_1b PF00579.20 GAP90523.1 - 4.9e-55 186.7 0.0 6.8e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DsrD PF08679.6 GAP90523.1 - 0.21 11.6 2.7 1.9 8.5 0.0 3.1 4 0 0 4 4 4 0 Dissimilatory sulfite reductase D (DsrD) DUF1517 PF07466.6 GAP90524.1 - 1.1 8.1 4.8 1.3 7.9 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) X PF00739.14 GAP90524.1 - 8.3 6.3 7.2 17 5.3 5.0 1.5 1 0 0 1 1 1 0 Trans-activation protein X PNGaseA PF12222.3 GAP90525.1 - 6.7e-124 414.0 0.1 1.2e-123 413.1 0.0 1.4 1 1 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A PBP PF01161.15 GAP90526.1 - 1.3e-08 34.8 0.2 1.7e-08 34.4 0.2 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein YXWGXW PF12779.2 GAP90527.1 - 0.69 9.8 14.9 0.1 12.5 6.9 2.2 2 0 0 2 2 2 0 YXWGXW repeat (2 copies) Ytp1 PF10355.4 GAP90528.1 - 9.5e-83 277.5 15.2 1.8e-82 276.6 10.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 GAP90528.1 - 3.4e-31 106.9 1.1 3.4e-31 106.9 0.7 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DUF897 PF05982.7 GAP90528.1 - 0.0016 17.3 0.5 0.0016 17.3 0.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF897) DUF3990 PF13151.1 GAP90531.1 - 2.2e-05 23.8 0.0 3.2e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3990) TruB_N PF01509.13 GAP90532.1 - 1.2e-45 155.2 0.3 2.4e-45 154.3 0.0 1.6 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) DUF4048 PF13257.1 GAP90533.1 - 3.9e-19 69.3 25.7 1.1e-16 61.3 0.6 4.1 1 1 3 4 4 4 3 Domain of unknown function (DUF4048) DNA_ligase_A_M PF01068.16 GAP90534.1 - 6.8e-24 84.3 0.0 1.4e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 GAP90534.1 - 1.1e-07 31.8 0.0 3.3e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 DNA ligase N terminus ERG2_Sigma1R PF04622.7 GAP90535.1 - 2.9e-95 317.5 0.5 3.4e-95 317.4 0.4 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein EXOSC1 PF10447.4 GAP90536.1 - 2.5e-29 101.0 0.9 3.8e-29 100.4 0.6 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 GAP90536.1 - 2.2e-14 52.4 0.1 5.2e-14 51.2 0.1 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.18 GAP90536.1 - 0.0021 18.0 0.4 0.018 15.1 0.3 2.1 1 1 0 1 1 1 1 S1 RNA binding domain SlyX PF04102.7 GAP90537.1 - 0.01 16.1 0.6 0.018 15.3 0.4 1.4 1 0 0 1 1 1 0 SlyX SSFA2_C PF14723.1 GAP90537.1 - 0.055 13.2 0.4 0.064 12.9 0.3 1.1 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus TerY-C PF15616.1 GAP90537.1 - 0.074 12.9 0.2 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain Caudo_TAP PF02413.12 GAP90537.1 - 0.08 13.1 1.3 0.14 12.3 0.9 1.4 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein Mito_fiss_reg PF05308.6 GAP90537.1 - 0.41 9.9 0.1 0.41 9.9 0.1 2.0 1 1 1 2 2 2 0 Mitochondrial fission regulator Sec2p PF06428.6 GAP90538.1 - 1.4e-11 44.0 2.3 2.3e-11 43.4 1.6 1.3 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p MbeD_MobD PF04899.7 GAP90538.1 - 0.019 14.8 2.4 0.35 10.7 1.6 2.6 1 1 0 1 1 1 0 MbeD/MobD like ATP-synt_ab PF00006.20 GAP90539.1 - 1.1e-112 374.7 0.0 1.6e-112 374.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 GAP90539.1 - 1.6e-19 70.4 0.3 3e-19 69.5 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 GAP90539.1 - 1.3e-13 50.9 2.2 6.2e-13 48.7 1.5 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain LcrG PF07216.7 GAP90539.1 - 0.082 12.9 0.0 22 5.1 0.0 2.5 2 0 0 2 2 2 0 LcrG protein DUF605 PF04652.11 GAP90539.1 - 2 7.7 19.1 3.4 6.9 13.3 1.3 1 0 0 1 1 1 0 Vta1 like Metallophos PF00149.23 GAP90540.1 - 6.5e-15 55.0 0.4 1.1e-14 54.3 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAP90540.1 - 0.00032 20.5 0.0 0.00069 19.4 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ACT_7 PF13840.1 GAP90541.1 - 1.3e-22 79.0 0.4 5e-17 61.1 0.0 2.3 2 0 0 2 2 2 2 ACT domain Methyltransf_32 PF13679.1 GAP90542.1 - 3.6e-19 68.8 0.3 1.9e-18 66.5 0.1 2.2 2 1 0 2 2 2 1 Methyltransferase domain Syntaxin-6_N PF09177.6 GAP90543.1 - 1.1e-23 83.3 0.1 4.8e-23 81.3 0.0 1.9 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 GAP90543.1 - 8.8e-14 50.9 3.4 8.8e-14 50.9 2.3 3.1 3 0 0 3 3 3 1 SNARE domain CENP-Q PF13094.1 GAP90543.1 - 0.0035 17.3 1.8 1.6 8.7 0.4 2.2 1 1 1 2 2 2 2 CENP-Q, a CENPA-CAD centromere complex subunit Phage_Gp23 PF10669.4 GAP90543.1 - 9.4 6.3 7.8 6 7.0 0.3 2.9 3 0 0 3 3 3 0 Protein gp23 (Bacteriophage A118) GLE1 PF07817.8 GAP90544.1 - 2.8e-24 85.4 0.0 9.7e-24 83.6 0.0 1.8 1 1 0 1 1 1 1 GLE1-like protein CortBP2 PF09727.4 GAP90544.1 - 0.026 14.0 8.5 0.044 13.2 5.9 1.3 1 0 0 1 1 1 0 Cortactin-binding protein-2 DUF2681 PF10883.3 GAP90544.1 - 1.1 9.5 6.8 2.4 8.4 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Macoilin PF09726.4 GAP90544.1 - 1.3 7.2 17.8 0.19 10.0 1.2 2.1 2 0 0 2 2 2 0 Transmembrane protein RPA_interact_M PF14767.1 GAP90544.1 - 1.6 9.5 8.3 1.9 9.3 4.5 2.1 2 0 0 2 2 2 0 Replication protein A interacting middle DivIC PF04977.10 GAP90544.1 - 7.3 6.1 8.2 83 2.7 0.0 2.4 2 0 0 2 2 2 0 Septum formation initiator COesterase PF00135.23 GAP90545.1 - 9.5e-83 278.7 4.3 1.9e-82 277.7 3.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAP90545.1 - 1.9e-05 24.3 0.0 4.1e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAP90545.1 - 0.0023 17.1 0.7 0.0023 17.1 0.5 1.9 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAP90545.1 - 0.062 13.0 0.2 0.18 11.5 0.1 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family ubiquitin PF00240.18 GAP90547.1 - 9.2e-20 69.8 0.3 1.9e-18 65.5 0.0 3.0 3 0 0 3 3 3 1 Ubiquitin family Rad60-SLD PF11976.3 GAP90547.1 - 1.7e-09 37.2 0.0 3.3e-07 29.9 0.0 3.6 4 0 0 4 4 4 1 Ubiquitin-2 like Rad60 SUMO-like DUF676 PF05057.9 GAP90547.1 - 5.5e-05 22.5 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Ubiquitin_2 PF14560.1 GAP90547.1 - 0.00012 22.2 0.2 0.0026 17.9 0.0 2.9 3 0 0 3 3 3 1 Ubiquitin-like domain PGAP1 PF07819.8 GAP90547.1 - 0.00017 21.2 0.0 0.00032 20.3 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 GAP90547.1 - 0.011 15.5 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Nucleoplasmin PF03066.10 GAP90547.1 - 1.7 8.1 13.8 1 8.8 6.8 2.3 2 0 0 2 2 2 0 Nucleoplasmin NOA36 PF06524.7 GAP90547.1 - 9.5 5.3 6.1 15 4.7 4.2 1.2 1 0 0 1 1 1 0 NOA36 protein RNB PF00773.14 GAP90548.1 - 1.4e-75 254.5 0.0 2.8e-75 253.6 0.0 1.5 1 0 0 1 1 1 1 RNB domain DUF4239 PF14023.1 GAP90548.1 - 0.23 10.7 0.1 0.45 9.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Ferritin_2 PF13668.1 GAP90549.1 - 1.1e-40 138.7 0.1 1.6e-40 138.1 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain SAP PF02037.22 GAP90550.1 - 4.5e-14 51.5 0.1 7.7e-14 50.7 0.1 1.4 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 GAP90550.1 - 0.0033 16.9 0.4 0.0076 15.7 0.3 1.6 1 1 0 1 1 1 1 HeH/LEM domain Pkinase PF00069.20 GAP90551.1 - 7.9e-20 71.0 0.0 1e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP90551.1 - 1.4e-08 34.1 0.0 2e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAP90551.1 - 3.2e-06 27.0 0.1 3.3e-05 23.7 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 GAP90551.1 - 0.00015 20.8 0.0 0.00026 20.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 GAP90551.1 - 0.00052 19.6 0.1 0.00078 19.0 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF2922 PF11148.3 GAP90551.1 - 0.021 14.4 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) RIO1 PF01163.17 GAP90551.1 - 0.028 13.7 0.0 0.056 12.7 0.0 1.5 1 0 0 1 1 1 0 RIO1 family DUF2306 PF10067.4 GAP90552.1 - 6.7e-14 51.8 9.1 2e-13 50.3 6.3 1.8 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) PrgI PF12666.2 GAP90552.1 - 7 6.8 9.1 0.99 9.5 1.2 2.7 3 0 0 3 3 3 0 PrgI family protein p450 PF00067.17 GAP90553.1 - 2.1e-71 240.8 0.0 2.6e-71 240.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 GAP90554.1 - 1.7e-76 249.6 12.5 1.6e-11 43.6 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 GAP90554.1 - 8.2e-09 34.1 8.3 0.0013 17.0 0.1 5.0 3 2 2 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAP90554.1 - 0.00058 18.7 0.1 0.19 10.4 0.0 3.3 2 2 1 3 3 3 2 Nup133 N terminal like FAD_binding_4 PF01565.18 GAP90556.1 - 1.9e-29 101.8 0.0 3.4e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 GAP90556.1 - 4.1e-12 45.9 0.0 1.3e-11 44.3 0.0 1.8 1 1 0 1 1 1 1 FAD linked oxidases, C-terminal domain ECH PF00378.15 GAP90557.1 - 1.9e-21 76.3 0.0 2.1e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 GAP90557.1 - 0.026 14.2 0.0 6.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 DUF1943 PF09172.6 GAP90559.1 - 0.052 12.3 0.0 0.21 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) ApoLp-III PF07464.6 GAP90559.1 - 0.16 11.9 0.2 0.36 10.8 0.1 1.5 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Ras PF00071.17 GAP90561.1 - 6.6e-23 80.8 0.0 4.7e-21 74.8 0.0 2.1 1 1 1 2 2 2 2 Ras family Miro PF08477.8 GAP90561.1 - 1.2e-11 45.1 0.0 4.6e-09 36.8 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein Arf PF00025.16 GAP90561.1 - 0.00013 21.2 0.0 0.0002 20.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAP90561.1 - 0.00096 19.0 0.0 0.0061 16.5 0.0 2.1 2 1 1 3 3 3 1 50S ribosome-binding GTPase SRPRB PF09439.5 GAP90561.1 - 0.0013 17.9 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GST_N PF02798.15 GAP90562.1 - 3.9e-12 46.1 0.0 7e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAP90562.1 - 4.2e-12 46.1 0.0 7.1e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAP90562.1 - 9e-11 41.6 0.0 1.6e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAP90562.1 - 4.6e-10 39.2 0.0 7.6e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAP90562.1 - 1.4e-09 37.7 0.0 3e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAP90562.1 - 2.6e-06 27.8 0.0 4.7e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Death PF00531.17 GAP90563.1 - 0.021 14.5 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Death domain DUF3720 PF12517.3 GAP90563.1 - 0.17 12.5 3.1 0.44 11.2 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3720) UQ_con PF00179.21 GAP90565.1 - 2.9e-49 166.0 0.0 4e-49 165.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme MS_channel PF00924.13 GAP90568.1 - 3.7e-22 78.6 2.0 7.2e-22 77.7 1.4 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_7 PF13499.1 GAP90568.1 - 0.015 15.4 0.2 0.54 10.4 0.1 2.9 2 1 1 3 3 3 0 EF-hand domain pair EF-hand_6 PF13405.1 GAP90568.1 - 0.02 14.7 0.1 1.1 9.3 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.27 GAP90568.1 - 0.064 12.5 0.7 0.16 11.3 0.5 1.8 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.1 GAP90568.1 - 0.094 12.3 0.1 0.24 11.0 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.1 GAP90568.1 - 0.15 11.4 0.1 0.43 10.0 0.1 1.8 1 0 0 1 1 1 0 EF hand SAC3_GANP PF03399.11 GAP90569.1 - 1.3e-37 129.3 0.0 2.1e-37 128.6 0.0 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 GAP90569.1 - 4e-05 23.4 0.0 8.7e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Phage_Mu_F PF04233.9 GAP90569.1 - 0.031 14.8 1.2 0.15 12.5 0.8 2.2 1 0 0 1 1 1 0 Phage Mu protein F like protein NMO PF03060.10 GAP90571.1 - 3.9e-69 233.3 1.4 4.7e-69 233.0 1.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 GAP90571.1 - 7.7e-07 28.3 0.0 0.012 14.5 0.0 2.4 2 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 GAP90571.1 - 0.5 9.1 6.0 0.91 8.2 4.1 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Cupin_2 PF07883.6 GAP90574.1 - 7.1e-25 86.3 0.5 1.4e-12 46.8 0.0 2.7 3 0 0 3 3 3 2 Cupin domain Cupin_1 PF00190.17 GAP90574.1 - 2e-24 85.6 0.0 3e-13 49.4 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.7 GAP90574.1 - 1.5e-11 43.4 0.1 4.9e-06 25.8 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 GAP90574.1 - 6.3e-07 29.1 0.0 1.3e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 AraC-like ligand binding domain MannoseP_isomer PF01050.13 GAP90574.1 - 5.4e-05 22.8 0.0 0.0023 17.5 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_6 PF12852.2 GAP90574.1 - 0.0004 20.0 0.1 0.092 12.3 0.1 2.6 2 1 0 2 2 2 1 Cupin 3-HAO PF06052.7 GAP90574.1 - 0.0015 17.9 0.0 0.011 15.1 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase Cupin_4 PF08007.7 GAP90574.1 - 0.032 13.4 0.0 0.87 8.7 0.0 2.1 2 0 0 2 2 2 0 Cupin superfamily protein DUF1971 PF09313.6 GAP90574.1 - 0.054 13.2 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) PI-PLC-X PF00388.14 GAP90575.1 - 1.1e-56 190.2 0.0 2.1e-56 189.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 GAP90575.1 - 5.2e-39 132.8 0.1 1.3e-38 131.6 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain PH PF00169.24 GAP90575.1 - 0.00014 22.0 0.1 0.00034 20.7 0.1 1.7 1 0 0 1 1 1 1 PH domain EF-hand_like PF09279.6 GAP90575.1 - 0.0064 16.4 0.0 0.025 14.6 0.0 2.0 1 1 1 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 GAP90575.1 - 0.031 14.0 0.0 0.095 12.5 0.0 1.8 1 0 0 1 1 1 0 C2 domain Cofilin_ADF PF00241.15 GAP90575.1 - 0.046 13.5 0.2 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein Egg_lysin PF01303.12 GAP90575.1 - 0.096 12.6 0.8 0.21 11.5 0.2 1.8 2 0 0 2 2 2 0 Egg lysin (Sperm-lysin) EF-hand_1 PF00036.27 GAP90575.1 - 0.098 12.0 0.1 0.49 9.8 0.0 2.3 2 0 0 2 2 2 0 EF hand zf-DHHC PF01529.15 GAP90576.1 - 2.6e-43 147.4 7.5 4.4e-43 146.6 5.2 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase FtsX PF02687.16 GAP90576.1 - 5.8 6.7 7.9 5.7 6.7 3.3 2.3 2 1 0 2 2 2 0 FtsX-like permease family Epimerase PF01370.16 GAP90577.1 - 5.9e-11 42.2 0.1 4.7e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAP90577.1 - 3.6e-06 25.9 0.0 0.0033 16.1 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAP90577.1 - 9.8e-06 24.6 0.2 2.2e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 GAP90577.1 - 1.8e-05 24.8 0.5 4.2e-05 23.6 0.1 1.8 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 GAP90577.1 - 0.00047 19.4 0.0 0.00074 18.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 GAP90577.1 - 0.00063 18.8 0.1 0.00089 18.3 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 GAP90577.1 - 0.0046 17.3 0.1 0.091 13.2 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent zf-C2H2 PF00096.21 GAP90578.1 - 1.4e-09 37.6 22.5 0.0035 17.6 0.5 5.6 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP90578.1 - 1.5e-09 37.5 20.8 0.043 14.1 0.1 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 GAP90578.1 - 6.1e-07 29.1 6.2 0.063 13.1 0.6 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_2 PF12756.2 GAP90578.1 - 5.2e-06 26.5 8.8 0.43 10.7 0.0 4.3 2 2 2 4 4 4 4 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 GAP90578.1 - 0.00033 20.6 3.8 0.93 9.7 0.3 4.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-CCHC_6 PF15288.1 GAP90578.1 - 0.061 13.0 0.0 0.061 13.0 0.0 2.7 3 0 0 3 3 3 0 Zinc knuckle OrfB_Zn_ribbon PF07282.6 GAP90578.1 - 0.067 12.8 2.2 1.8 8.2 0.1 2.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-met PF12874.2 GAP90578.1 - 0.7 10.1 10.5 8.3 6.7 0.1 4.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-Di19 PF05605.7 GAP90578.1 - 2.6 8.2 16.7 1.1 9.3 1.4 3.9 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding UQ_con PF00179.21 GAP90579.1 - 2.4e-21 75.6 0.0 3.3e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAP90579.1 - 0.026 14.2 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 GAP90579.1 - 0.053 13.4 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain IPPT PF01715.12 GAP90580.1 - 2.9e-52 177.1 0.1 1.2e-51 175.2 0.1 1.9 1 1 1 2 2 2 1 IPP transferase zf-C2H2_jaz PF12171.3 GAP90580.1 - 2.8e-06 27.3 0.2 1e-05 25.4 0.2 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAP90580.1 - 7.4e-06 25.9 0.2 1.6e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_17 PF13207.1 GAP90580.1 - 3.4e-05 24.6 0.2 9.8e-05 23.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain IPT PF01745.11 GAP90580.1 - 0.00042 19.5 0.0 0.0011 18.2 0.0 1.7 1 0 0 1 1 1 1 Isopentenyl transferase AAA_28 PF13521.1 GAP90580.1 - 0.00098 19.1 0.9 0.055 13.4 0.0 3.3 3 2 0 3 3 3 1 AAA domain AAA_22 PF13401.1 GAP90580.1 - 0.0047 17.0 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAP90580.1 - 0.0056 16.9 0.0 0.049 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 GAP90580.1 - 0.014 15.3 0.1 0.086 12.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 GAP90580.1 - 0.017 14.8 0.0 0.046 13.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 GAP90580.1 - 0.019 14.3 0.0 0.061 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 GAP90580.1 - 0.036 13.2 0.0 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.22 GAP90580.1 - 0.05 13.9 0.0 0.34 11.2 0.0 2.4 3 1 0 3 3 3 0 ABC transporter DUF87 PF01935.12 GAP90580.1 - 0.5 10.1 2.1 0.5 10.1 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function DUF87 AhpC-TSA PF00578.16 GAP90581.1 - 9.8e-38 128.6 0.0 1.3e-37 128.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 GAP90581.1 - 3e-14 52.7 0.0 3.8e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 GAP90581.1 - 3e-12 45.9 0.0 5e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SecY PF00344.15 GAP90582.1 - 1.4e-95 320.1 9.4 1.8e-95 319.8 6.5 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 GAP90582.1 - 2.1e-18 65.4 0.3 7.2e-18 63.8 0.2 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p Thioesterase PF00975.15 GAP90583.1 - 4.2e-19 69.6 0.0 4.3e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 GAP90583.1 - 0.0012 18.7 0.0 0.0014 18.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family adh_short PF00106.20 GAP90584.1 - 3.2e-18 66.1 0.1 4.1e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 GAP90584.1 - 1.2e-07 31.9 0.0 1.8e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 GAP90584.1 - 6.2e-07 29.2 0.3 2.5e-06 27.2 0.2 1.8 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAP90584.1 - 0.00013 21.8 0.0 0.00018 21.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase F420_oxidored PF03807.12 GAP90584.1 - 0.0019 18.5 0.1 0.011 16.0 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 GAP90584.1 - 0.0026 17.2 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 GAP90584.1 - 0.014 15.5 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1776 PF08643.5 GAP90584.1 - 0.047 12.8 0.2 0.065 12.3 0.1 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 2-Hacid_dh_C PF02826.14 GAP90584.1 - 0.072 12.2 0.1 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PS-DH PF14765.1 GAP90585.1 - 1.4e-12 47.3 0.1 7e-08 31.9 0.0 2.5 2 1 1 3 3 3 2 Polyketide synthase dehydratase KR PF08659.5 GAP90585.1 - 6.5e-09 35.7 0.1 1.2e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 KR domain ADH_zinc_N_2 PF13602.1 GAP90585.1 - 2.1e-06 28.6 0.0 5.9e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.20 GAP90585.1 - 3.9e-06 26.8 0.1 1e-05 25.5 0.1 1.8 1 0 0 1 1 1 1 short chain dehydrogenase BBE PF08031.7 GAP90586.1 - 5.9e-09 35.6 0.0 1.4e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like ABC_tran PF00005.22 GAP90587.1 - 2.4e-53 180.1 0.0 1e-30 106.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAP90587.1 - 1e-42 146.4 22.4 7.2e-24 84.6 3.6 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_23 PF13476.1 GAP90587.1 - 2.7e-09 37.6 0.5 3.5e-05 24.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 GAP90587.1 - 1.1e-08 34.5 3.0 0.0022 17.2 0.3 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAP90587.1 - 1.2e-07 32.0 0.0 0.28 11.0 0.0 4.5 4 0 0 4 4 4 2 AAA domain AAA_10 PF12846.2 GAP90587.1 - 5.4e-07 29.3 0.1 0.0058 16.1 0.0 3.1 3 0 0 3 3 3 2 AAA-like domain AAA_29 PF13555.1 GAP90587.1 - 3.6e-06 26.4 0.8 0.1 12.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 GAP90587.1 - 5.5e-06 25.9 0.1 0.041 13.2 0.0 2.7 3 0 0 3 3 2 2 AAA domain T2SE PF00437.15 GAP90587.1 - 8.7e-05 21.5 0.5 0.013 14.3 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.1 GAP90587.1 - 0.00017 21.6 0.1 0.29 11.0 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 GAP90587.1 - 0.00021 20.4 0.0 0.62 9.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 GAP90587.1 - 0.00025 20.2 1.2 0.14 11.2 0.3 2.4 2 0 0 2 2 2 2 Zeta toxin DUF87 PF01935.12 GAP90587.1 - 0.0007 19.4 0.9 0.081 12.7 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 GAP90587.1 - 0.00086 18.8 0.2 0.26 10.7 0.1 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 GAP90587.1 - 0.0012 18.7 0.1 0.096 12.6 0.1 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 GAP90587.1 - 0.0029 17.7 0.1 24 5.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain MobB PF03205.9 GAP90587.1 - 0.006 16.2 1.5 11 5.7 0.0 4.1 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 GAP90587.1 - 0.0068 16.9 0.0 5.1 7.6 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein ResIII PF04851.10 GAP90587.1 - 0.011 15.6 0.1 2.5 7.9 0.1 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_17 PF13207.1 GAP90587.1 - 0.012 16.4 0.1 12 6.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 GAP90587.1 - 0.027 14.7 0.2 7.4 6.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 GAP90587.1 - 0.031 14.4 0.3 4.8 7.3 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 GAP90587.1 - 0.041 13.3 0.3 1.5 8.2 0.0 3.1 3 0 0 3 3 3 0 DEAD/DEAH box helicase Arch_ATPase PF01637.13 GAP90587.1 - 0.077 12.6 0.0 0.92 9.1 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase TrwB_AAD_bind PF10412.4 GAP90587.1 - 0.081 11.5 2.7 4.6 5.7 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.1 GAP90587.1 - 0.1 12.1 1.2 15 5.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 GAP90587.1 - 0.11 12.0 2.1 11 5.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 GAP90587.1 - 0.12 12.5 0.2 38 4.5 0.0 3.3 3 0 0 3 3 3 0 RNA helicase CbiA PF01656.18 GAP90587.1 - 0.74 9.1 3.6 1.7 8.0 0.0 2.7 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain SnoaL_2 PF12680.2 GAP90589.1 - 0.001 19.4 2.3 0.0017 18.7 1.6 1.4 1 1 0 1 1 1 1 SnoaL-like domain Abhydrolase_6 PF12697.2 GAP90590.1 - 4.5e-22 79.0 3.4 5.4e-22 78.7 2.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP90590.1 - 6.8e-12 45.4 0.2 2.3e-11 43.6 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP90590.1 - 1e-08 35.0 0.0 3.6e-08 33.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 GAP90590.1 - 0.011 15.1 0.2 0.016 14.6 0.1 1.3 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Pneumo_M2 PF07380.6 GAP90590.1 - 0.064 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Pneumovirus M2 protein KR PF08659.5 GAP90591.1 - 1.9e-21 76.5 2.9 2e-21 76.4 0.1 2.0 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 GAP90591.1 - 1.5e-14 54.2 4.2 1.5e-14 54.2 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.20 GAP90591.1 - 0.00011 22.3 0.0 0.00021 21.5 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.21 GAP90592.1 - 2.7e-18 65.7 0.0 6e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 GAP90592.1 - 1.1e-15 57.8 0.0 2.4e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP90592.1 - 1.5e-10 41.4 0.0 3.6e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP90592.1 - 2.2e-09 37.8 0.0 7.8e-09 36.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP90592.1 - 4.3e-09 36.1 0.0 9.7e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP90592.1 - 1.4e-08 34.6 0.0 2.5e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP90592.1 - 1.6e-05 24.1 0.0 6.5e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family ADH_zinc_N_2 PF13602.1 GAP90592.1 - 0.00056 20.7 0.0 0.0047 17.8 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase p450 PF00067.17 GAP90593.1 - 1.6e-44 152.1 0.0 2e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SAM_decarbox PF01536.11 GAP90594.1 - 7.7e-88 294.3 0.0 4e-84 282.1 0.0 3.0 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase ParA PF10609.4 GAP90595.1 - 6.9e-36 121.9 0.1 1.2e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 GAP90595.1 - 6.4e-15 55.0 0.0 1.2e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 GAP90595.1 - 1.5e-07 30.8 0.0 2.4e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 GAP90595.1 - 1.5e-05 24.9 0.0 5e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 GAP90595.1 - 1.6e-05 24.1 0.3 3e-05 23.2 0.2 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase YhjQ PF06564.7 GAP90595.1 - 0.00093 18.6 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 YhjQ protein ArgK PF03308.11 GAP90595.1 - 0.0013 17.6 0.3 0.0023 16.7 0.2 1.4 1 0 0 1 1 1 1 ArgK protein AAA_25 PF13481.1 GAP90595.1 - 0.0022 17.3 0.0 0.004 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 GAP90595.1 - 0.02 14.0 0.3 0.039 13.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 APS_kinase PF01583.15 GAP90595.1 - 0.046 13.3 0.1 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_26 PF13500.1 GAP90595.1 - 0.047 13.2 0.6 4.9 6.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 GAP90595.1 - 0.14 12.1 0.3 0.95 9.4 0.2 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.24 GAP90597.1 - 4.7e-14 52.7 0.0 1.5e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAP90597.1 - 1.7e-05 24.8 0.1 0.0013 18.7 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAP90597.1 - 0.00062 19.9 0.0 0.0044 17.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 GAP90597.1 - 0.0029 16.6 0.0 0.0048 15.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 GAP90597.1 - 0.017 14.8 0.0 0.043 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 GAP90597.1 - 0.076 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 GAP90597.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Na_Ca_ex PF01699.19 GAP90598.1 - 5.8e-27 93.9 29.9 1.3e-14 53.9 9.0 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Pkinase PF00069.20 GAP90599.1 - 3e-06 26.5 0.0 1.3e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP90599.1 - 0.042 12.9 0.0 0.068 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Abhydrolase_2 PF02230.11 GAP90600.1 - 1.7e-26 93.0 0.0 3.9e-26 91.8 0.0 1.6 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase MFS_1 PF07690.11 GAP90600.1 - 6.3e-21 74.4 52.8 2e-12 46.4 10.0 2.5 3 0 0 3 3 3 2 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 GAP90600.1 - 3.9e-08 33.4 0.5 0.0015 18.4 0.1 2.7 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAP90600.1 - 5.2e-08 32.3 0.0 5.5e-06 25.7 0.0 2.7 2 1 1 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAP90600.1 - 9e-08 31.9 0.0 5.2e-07 29.5 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 GAP90600.1 - 0.0035 16.5 0.0 0.0059 15.8 0.0 1.3 1 0 0 1 1 1 1 Secretory lipase bZIP_1 PF00170.16 GAP90601.1 - 0.45 10.4 8.4 0.087 12.7 2.8 1.9 1 1 0 2 2 2 0 bZIP transcription factor DEAD PF00270.24 GAP90605.1 - 1.5e-42 144.9 0.0 2.1e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP90605.1 - 1.9e-23 82.1 0.1 3.9e-23 81.0 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 GAP90605.1 - 0.059 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit CD99L2 PF12301.3 GAP90605.1 - 0.064 12.9 2.9 0.12 12.1 2.0 1.3 1 0 0 1 1 1 0 CD99 antigen like protein 2 API5 PF05918.6 GAP90605.1 - 0.2 10.1 4.0 0.28 9.6 2.8 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DnaJ PF00226.26 GAP90606.1 - 7.2e-08 32.0 0.6 1.3e-07 31.2 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain DUF2360 PF10152.4 GAP90606.1 - 0.084 13.1 2.6 0.089 13.0 1.0 1.5 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Abhydrolase_2 PF02230.11 GAP90607.1 - 2e-20 73.2 0.0 7.4e-20 71.3 0.0 1.8 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 GAP90607.1 - 1.2e-06 28.3 0.0 2.3e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP90607.1 - 0.013 15.4 0.8 0.045 13.6 0.5 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family LIP PF03583.9 GAP90607.1 - 0.019 14.1 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase GatB_N PF02934.10 GAP90609.1 - 2.4e-101 338.4 0.0 3.3e-101 337.9 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 GAP90609.1 - 9.5e-05 22.1 0.0 0.00022 20.9 0.0 1.5 1 0 0 1 1 1 1 GatB domain RNase_T PF00929.19 GAP90611.1 - 1.9e-09 38.0 0.0 5.1e-09 36.6 0.0 1.8 2 0 0 2 2 2 1 Exonuclease zf-C2H2_6 PF13912.1 GAP90611.1 - 0.0025 17.6 2.0 0.0025 17.6 1.4 2.6 3 0 0 3 3 3 1 C2H2-type zinc finger DNA_pol_A_exo1 PF01612.15 GAP90611.1 - 0.04 13.3 0.1 0.099 12.1 0.0 1.7 2 0 0 2 2 2 0 3'-5' exonuclease BAF1_ABF1 PF04684.8 GAP90611.1 - 4.9 5.8 10.4 8.1 5.1 7.2 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor AA_permease_2 PF13520.1 GAP90612.1 - 1.4e-43 149.0 46.3 1.8e-43 148.7 32.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAP90612.1 - 1.5e-11 43.3 44.8 7.1e-11 41.1 31.0 1.8 1 1 0 1 1 1 1 Amino acid permease DUF3328 PF11807.3 GAP90614.1 - 2e-23 83.1 0.3 2.6e-23 82.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Acetyltransf_1 PF00583.19 GAP90615.1 - 2.8e-08 33.6 0.1 5.4e-08 32.7 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAP90615.1 - 7.7e-06 25.9 0.0 1.8e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAP90615.1 - 6.9e-05 22.6 0.0 0.013 15.3 0.0 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAP90615.1 - 0.00071 19.6 0.1 0.005 16.9 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain DUF1832 PF08870.6 GAP90615.1 - 0.02 14.6 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1832) FR47 PF08445.5 GAP90615.1 - 0.052 13.3 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein DUF3749 PF12568.3 GAP90615.1 - 0.078 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF309 PF03745.9 GAP90615.1 - 0.099 12.1 0.1 10 5.6 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF309) SF3b1 PF08920.5 GAP90617.1 - 0.99 9.4 5.0 2 8.4 3.5 1.9 1 1 0 1 1 1 0 Splicing factor 3B subunit 1 zf-C2H2_4 PF13894.1 GAP90619.1 - 3.6e-06 26.9 12.7 0.00061 19.9 1.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAP90619.1 - 5.9e-06 26.3 4.0 5.9e-06 26.3 2.8 3.0 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.21 GAP90619.1 - 1.8e-05 24.8 11.7 0.0069 16.6 1.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type DUF4482 PF14818.1 GAP90619.1 - 0.2 12.2 1.6 30 5.2 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) PH_10 PF15411.1 GAP90620.1 - 1.2e-10 41.6 0.1 6.9e-10 39.1 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain MFS_1 PF07690.11 GAP90621.1 - 1.3e-45 155.6 57.4 4.1e-45 154.0 39.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP90621.1 - 8.2e-13 47.7 11.0 8.2e-13 47.7 7.7 3.1 2 1 0 3 3 3 1 Sugar (and other) transporter Phosphodiest PF01663.17 GAP90622.1 - 4.6e-08 32.7 0.3 2.8e-07 30.2 0.1 2.0 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 GAP90622.1 - 0.00057 19.1 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 Sulfatase GST_C_3 PF14497.1 GAP90623.1 - 4.4e-07 30.3 0.0 9.2e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAP90623.1 - 2.9e-05 23.9 0.0 5.8e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAP90623.1 - 0.00046 20.2 0.0 0.0069 16.5 0.0 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAP90623.1 - 0.054 13.3 0.1 0.17 11.7 0.1 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Antimicrobial_8 PF08103.6 GAP90623.1 - 0.12 12.3 0.2 0.34 10.9 0.1 1.7 1 0 0 1 1 1 0 Uperin family DNA_primase_S PF01896.14 GAP90625.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase small subunit Glyco_hydro_18 PF00704.23 GAP90626.1 - 6.1e-79 265.9 3.0 9.6e-79 265.3 2.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 GAP90626.1 - 2.6e-08 33.6 14.5 2.6e-08 33.6 10.1 4.1 4 0 0 4 4 4 2 Chitin recognition protein LysM PF01476.15 GAP90627.1 - 4e-25 87.4 4.9 2e-08 33.9 0.1 6.0 6 0 0 6 6 6 5 LysM domain UPF0203 PF05254.7 GAP90627.1 - 0.08 12.8 0.3 0.69 9.8 0.0 2.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) Phosphoprotein PF00922.12 GAP90627.1 - 4.4 6.4 7.3 0.17 11.0 0.5 1.8 2 0 0 2 2 2 0 Vesiculovirus phosphoprotein MFS_1 PF07690.11 GAP90629.1 - 5.3e-40 137.2 31.7 7.8e-29 100.4 8.0 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 GAP90629.1 - 0.0016 17.2 6.4 0.0045 15.7 1.0 2.5 2 1 0 2 2 2 2 BT1 family OATP PF03137.15 GAP90629.1 - 0.076 11.0 1.6 0.26 9.3 0.5 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family GFA PF04828.9 GAP90630.1 - 1.4e-15 56.9 0.8 2.1e-15 56.4 0.6 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 GAP90630.1 - 0.037 13.7 0.2 0.037 13.7 0.1 2.4 3 0 0 3 3 3 0 Nudix N-terminal Cys_rich_CWC PF14375.1 GAP90630.1 - 0.27 11.1 8.1 0.13 12.1 2.4 2.1 2 0 0 2 2 2 0 Cysteine-rich CWC Mito_fiss_reg PF05308.6 GAP90630.1 - 4.2 6.6 5.9 5.1 6.3 4.1 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Zn_clus PF00172.13 GAP90631.1 - 5.2e-09 35.8 9.0 8.7e-09 35.1 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAP90631.1 - 0.0061 15.2 0.0 0.0084 14.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Flavodoxin_5 PF12724.2 GAP90631.1 - 0.05 13.6 0.0 0.081 12.9 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin domain Pkinase PF00069.20 GAP90632.1 - 0.00031 19.9 0.0 0.038 13.1 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAP90632.1 - 0.16 11.0 0.0 1.7 7.6 0.0 2.5 4 0 0 4 4 4 0 Protein tyrosine kinase Fungal_trans PF04082.13 GAP90633.1 - 3.9e-15 55.4 9.1 7.8e-15 54.4 5.0 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain Ribosomal_60s PF00428.14 GAP90633.1 - 0.016 15.5 4.3 0.016 15.5 3.0 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein FAM176 PF14851.1 GAP90633.1 - 0.87 9.2 7.8 5.4 6.6 1.3 2.6 2 0 0 2 2 2 0 FAM176 family Nucleoplasmin PF03066.10 GAP90633.1 - 1.1 8.8 13.9 0.73 9.3 1.6 2.9 3 0 0 3 3 3 0 Nucleoplasmin Fungal_trans_2 PF11951.3 GAP90633.1 - 1.2 7.6 10.2 1.7 7.1 0.1 2.6 3 0 0 3 3 3 0 Fungal specific transcription factor domain RXT2_N PF08595.6 GAP90633.1 - 1.5 8.5 9.3 5.5 6.7 0.5 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal Peptidase_S49_N PF08496.5 GAP90633.1 - 1.9 8.3 4.1 4.8 6.9 2.9 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PBP1_TM PF14812.1 GAP90633.1 - 5.4 7.4 14.9 0.47 10.7 0.5 3.1 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C2H2_3 PF13878.1 GAP90634.1 - 9.3e-08 31.5 0.6 1.6e-07 30.7 0.4 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO DUF3379 PF11859.3 GAP90634.1 - 0.054 12.6 0.2 0.08 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) Vma12 PF11712.3 GAP90635.1 - 1.3e-35 122.1 0.0 2.1e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Inhibitor_I53 PF11714.3 GAP90635.1 - 0.15 12.1 1.9 0.16 11.9 0.2 1.8 2 0 0 2 2 2 0 Thrombin inhibitor Madanin TerB-C PF15615.1 GAP90635.1 - 0.37 11.0 2.4 2.1 8.5 0.1 2.7 3 0 0 3 3 3 0 TerB-C domain polyprenyl_synt PF00348.12 GAP90636.1 - 4.7e-53 179.7 0.0 9.5e-50 168.8 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 GAP90636.1 - 0.0013 18.1 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Hydrophobin PF01185.13 GAP90637.1 - 0.018 15.4 4.8 0.12 12.8 3.3 2.0 1 1 0 1 1 1 0 Fungal hydrophobin WEMBL PF05701.6 GAP90639.1 - 0.03 12.7 0.8 0.039 12.4 0.5 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF3176 PF11374.3 GAP90640.1 - 4.1e-15 55.6 2.5 7.4e-15 54.7 0.2 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3176) F-box-like PF12937.2 GAP90642.1 - 0.0032 17.1 1.5 0.046 13.4 0.2 2.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 GAP90642.1 - 0.0051 16.4 0.7 0.035 13.7 0.4 2.4 2 0 0 2 2 2 1 F-box domain zf-RanBP PF00641.13 GAP90642.1 - 0.047 12.8 1.1 0.13 11.3 0.7 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others DUF485 PF04341.7 GAP90642.1 - 1.5 8.5 6.5 0.17 11.6 0.5 2.3 3 0 0 3 3 3 0 Protein of unknown function, DUF485 TPR_2 PF07719.12 GAP90643.1 - 1.2e-07 31.1 15.6 0.001 18.8 0.1 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 GAP90643.1 - 3.4e-07 29.5 11.1 0.0044 16.5 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAP90643.1 - 6.9e-07 28.5 4.1 0.17 11.7 0.1 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAP90643.1 - 1.5e-05 24.5 13.5 0.018 14.6 0.2 5.8 5 1 1 6 6 6 3 TPR repeat TPR_12 PF13424.1 GAP90643.1 - 4.2e-05 23.3 14.8 0.016 15.1 0.6 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAP90643.1 - 0.00017 21.3 7.5 0.012 15.5 0.5 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAP90643.1 - 0.00073 19.1 4.4 0.54 10.1 0.0 5.5 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAP90643.1 - 0.0081 16.7 13.8 38 5.3 0.1 7.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 GAP90643.1 - 0.046 14.1 17.6 0.12 12.9 0.1 5.3 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAP90643.1 - 0.074 13.2 3.6 11 6.5 0.0 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAP90643.1 - 0.087 13.1 6.7 0.92 9.8 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAP90643.1 - 0.29 11.8 23.2 4 8.2 1.0 7.0 7 1 0 7 7 7 0 Tetratricopeptide repeat DJ-1_PfpI PF01965.19 GAP90644.1 - 1.8e-26 92.3 0.1 3.2e-26 91.5 0.1 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 GAP90644.1 - 1.2e-12 47.0 0.1 3.1e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family DUF4066 PF13278.1 GAP90644.1 - 0.00015 21.0 0.0 0.00025 20.3 0.0 1.4 1 0 0 1 1 1 1 Putative amidotransferase GATase_3 PF07685.9 GAP90644.1 - 0.077 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Amidohydro_1 PF01979.15 GAP90645.1 - 4.8e-20 72.4 1.7 2.1e-10 40.8 0.0 3.1 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 GAP90645.1 - 1.8e-19 70.8 0.3 2.9e-18 66.8 0.2 2.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 GAP90645.1 - 7.3e-11 41.7 0.1 1.7e-10 40.5 0.1 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 GAP90645.1 - 1.5e-08 34.3 0.0 4.8e-05 22.7 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family DUF3296 PF11726.3 GAP90647.1 - 0.11 12.1 0.1 0.13 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) Fungal_trans PF04082.13 GAP90648.1 - 4.9e-09 35.4 0.1 8e-09 34.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 GAP90649.1 - 9.7e-30 103.4 0.3 8.5e-17 60.8 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP90649.1 - 2.9e-09 36.6 11.4 4.9e-09 35.9 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 GAP90649.1 - 0.074 12.7 4.6 0.21 11.3 3.2 1.8 1 0 0 1 1 1 0 AT hook motif Glyco_hydro_92 PF07971.7 GAP90652.1 - 1.1e-173 578.4 0.0 1.4e-173 578.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 ADH_zinc_N PF00107.21 GAP90653.1 - 6.1e-21 74.3 0.0 1e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAP90653.1 - 7.9e-08 33.2 0.0 2.3e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Aldo_ket_red PF00248.16 GAP90653.1 - 0.063 12.0 0.0 0.095 11.4 0.0 1.2 1 0 0 1 1 1 0 Aldo/keto reductase family Myb_DNA-bind_6 PF13921.1 GAP90654.1 - 6.5e-14 51.7 4.0 2.8e-11 43.3 0.2 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 GAP90654.1 - 6.6e-14 51.6 1.1 5.9e-06 26.2 0.0 4.0 3 2 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 GAP90654.1 - 0.002 18.2 5.8 0.014 15.4 0.7 3.0 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain HET PF06985.6 GAP90655.1 - 2.9e-24 85.8 0.0 6.2e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Metallophos PF00149.23 GAP90659.1 - 4.2e-14 52.3 1.1 1.7e-13 50.4 0.8 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAP90659.1 - 7.4e-12 45.3 0.7 1.6e-11 44.2 0.5 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aldolase_II PF00596.16 GAP90659.1 - 0.098 12.2 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Class II Aldolase and Adducin N-terminal domain Abhydrolase_6 PF12697.2 GAP90660.1 - 1.1e-26 94.1 4.9 1.3e-26 93.8 3.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP90660.1 - 1.3e-18 67.4 0.2 5.7e-16 58.7 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP90660.1 - 4.3e-13 49.2 0.0 1.3e-12 47.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 GAP90660.1 - 0.0036 16.5 0.0 0.69 9.1 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S15 PF02129.13 GAP90660.1 - 0.014 14.7 0.0 0.029 13.7 0.0 1.5 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Thioesterase PF00975.15 GAP90660.1 - 0.022 14.9 0.0 0.036 14.2 0.0 1.5 1 1 0 1 1 1 0 Thioesterase domain Abhydrolase_4 PF08386.5 GAP90660.1 - 0.031 14.1 0.1 0.063 13.1 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_3 PF07859.8 GAP90660.1 - 0.049 13.1 0.9 0.42 10.1 0.2 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF2048 PF09752.4 GAP90660.1 - 0.073 11.9 1.1 0.33 9.7 0.4 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) Hydrolase_4 PF12146.3 GAP90660.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative lysophospholipase p450 PF00067.17 GAP90661.1 - 1e-48 166.0 0.0 2.2e-48 164.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 NAD_binding_4 PF07993.7 GAP90661.1 - 9.8e-26 90.1 0.0 1.5e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 GAP90661.1 - 1.7e-10 40.7 0.0 5.3e-10 39.1 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family AMP-binding PF00501.23 GAP90661.1 - 0.00089 17.7 0.0 0.0058 15.0 0.0 2.0 1 1 1 2 2 2 1 AMP-binding enzyme NAD_binding_10 PF13460.1 GAP90661.1 - 0.0023 17.9 1.0 0.51 10.3 0.1 2.4 2 0 0 2 2 2 2 NADH(P)-binding PP-binding PF00550.20 GAP90661.1 - 0.012 15.8 0.0 0.044 14.0 0.0 2.0 1 0 0 1 1 1 0 Phosphopantetheine attachment site Semialdhyde_dh PF01118.19 GAP90661.1 - 0.019 15.2 0.0 0.049 13.9 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain zf-MYND PF01753.13 GAP90662.1 - 5.2e-09 35.8 6.4 5.2e-09 35.8 4.5 2.0 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.11 GAP90662.1 - 0.71 9.5 12.5 0.21 11.2 6.5 1.8 2 0 0 2 2 2 0 HIT zinc finger eIF3_N PF09440.5 GAP90663.1 - 2.9e-46 156.9 0.4 5.9e-46 155.9 0.3 1.6 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 GAP90663.1 - 1.3e-11 44.7 0.0 3.4e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 PCI domain TPR_20 PF14561.1 GAP90663.1 - 0.53 10.4 3.2 23 5.1 0.0 3.9 4 1 1 5 5 5 0 Tetratricopeptide repeat Img2 PF05046.9 GAP90664.1 - 8.7e-14 51.5 0.1 1.2e-13 51.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) PALP PF00291.20 GAP90665.1 - 5.7e-50 170.2 5.1 6.7e-50 170.0 3.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Mgm101p PF06420.7 GAP90665.1 - 0.013 14.8 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 Collagen PF01391.13 GAP90666.1 - 0.00071 19.0 3.9 0.00071 19.0 2.7 3.1 3 1 0 3 3 3 1 Collagen triple helix repeat (20 copies) p450 PF00067.17 GAP90667.1 - 9e-32 110.1 0.0 1.1e-31 109.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 GAP90668.1 - 2.1e-93 313.3 23.9 2.5e-93 313.1 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP90668.1 - 3.2e-26 91.8 30.2 3.2e-26 91.8 21.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily RskA PF10099.4 GAP90668.1 - 0.13 11.9 2.7 3.3 7.3 0.0 2.8 3 0 0 3 3 3 0 Anti-sigma-K factor rskA TauD PF02668.11 GAP90669.1 - 2e-22 80.0 0.0 4e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Hydrolase_like PF13242.1 GAP90669.1 - 1.6e-11 43.7 0.0 5.4e-11 42.0 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 GAP90669.1 - 9e-11 42.2 0.0 4.2e-10 40.1 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 GAP90669.1 - 0.00059 20.0 0.1 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase CsiD PF08943.5 GAP90669.1 - 0.0025 16.7 0.0 0.0046 15.8 0.0 1.3 1 0 0 1 1 1 1 CsiD Hydrolase PF00702.21 GAP90669.1 - 0.043 14.2 0.0 0.67 10.3 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase p450 PF00067.17 GAP90671.1 - 1.3e-36 126.1 0.0 1.6e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 GAP90672.1 - 6.3e-88 294.9 0.0 8.6e-88 294.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAP90672.1 - 5.7e-14 52.8 0.1 1.3e-13 51.6 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Clathrin PF00637.15 GAP90673.1 - 1e-21 77.0 1.1 2.4e-19 69.3 0.1 2.7 2 0 0 2 2 2 2 Region in Clathrin and VPS WD40 PF00400.27 GAP90673.1 - 0.00014 21.5 0.4 0.14 12.0 0.1 3.9 3 1 0 3 3 3 1 WD domain, G-beta repeat zf-RING_2 PF13639.1 GAP90673.1 - 0.00047 19.9 1.5 0.0012 18.6 1.1 1.7 1 1 0 1 1 1 1 Ring finger domain Vps39_1 PF10366.4 GAP90673.1 - 0.001 19.0 0.1 0.0068 16.4 0.0 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 TPR_7 PF13176.1 GAP90673.1 - 0.0093 15.7 1.3 0.35 10.7 0.1 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat CENP-B_dimeris PF09026.5 GAP90673.1 - 0.07 13.3 13.6 0.23 11.7 9.4 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-RING_5 PF14634.1 GAP90673.1 - 0.076 12.7 1.6 0.19 11.4 1.1 1.7 1 1 0 1 1 1 0 zinc-RING finger domain TPR_2 PF07719.12 GAP90673.1 - 0.092 12.7 0.2 0.54 10.3 0.2 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat PSCyt2 PF07583.6 GAP90673.1 - 0.18 11.2 3.9 0.6 9.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1549) Daxx PF03344.10 GAP90673.1 - 1.5 7.2 14.1 2.6 6.4 9.8 1.3 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 GAP90673.1 - 9.3 4.0 21.6 14 3.4 14.9 1.1 1 0 0 1 1 1 0 Nop14-like family Apc1 PF12859.2 GAP90674.1 - 1.5e-27 95.8 0.0 5.9e-27 93.9 0.0 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 GAP90674.1 - 1.3e-07 31.4 2.4 0.21 11.8 0.0 5.1 5 0 0 5 5 5 2 Proteasome/cyclosome repeat LBP_BPI_CETP_C PF02886.12 GAP90674.1 - 0.037 13.2 1.0 0.57 9.3 0.0 2.2 2 0 0 2 2 2 0 LBP / BPI / CETP family, C-terminal domain SprT-like PF10263.4 GAP90675.1 - 1.7e-05 24.4 0.2 2.5e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 SprT-like family DUF3294 PF07957.6 GAP90675.1 - 0.069 12.6 0.0 0.099 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) DUF3267 PF11667.3 GAP90675.1 - 0.078 13.1 4.1 4.1 7.6 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3267) MFS_1 PF07690.11 GAP90676.1 - 1.8e-33 115.7 28.5 1.8e-33 115.7 19.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Bromodomain PF00439.20 GAP90677.1 - 1.1e-18 66.9 0.3 1.1e-18 66.9 0.2 2.5 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.8 GAP90677.1 - 1.4e-09 37.5 0.1 3.8e-09 36.1 0.1 1.8 1 0 0 1 1 1 1 Bromodomain associated Imm6 PF14434.1 GAP90677.1 - 0.22 11.2 3.8 13 5.5 0.0 3.2 3 0 0 3 3 3 0 Immunity protein Imm6 VanZ PF04892.7 GAP90678.1 - 9.3e-15 54.7 2.2 1.3e-14 54.2 1.5 1.1 1 0 0 1 1 1 1 VanZ like family DUF4401 PF14351.1 GAP90678.1 - 0.0029 16.6 1.3 0.0037 16.3 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) ABC_membrane_3 PF13748.1 GAP90678.1 - 0.14 11.1 0.8 0.18 10.8 0.6 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region DUF2678 PF10856.3 GAP90678.1 - 0.29 10.8 1.6 0.78 9.4 0.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2678) Pyridoxal_deC PF00282.14 GAP90679.1 - 4.7e-54 183.2 0.0 6.1e-47 159.8 0.1 2.5 1 1 1 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 GAP90679.1 - 0.00014 21.1 0.2 0.00024 20.3 0.2 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 GAP90679.1 - 0.0055 15.4 0.1 0.0099 14.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Abhydrolase_3 PF07859.8 GAP90680.1 - 2.8e-53 180.6 1.0 6.5e-53 179.4 0.7 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 GAP90680.1 - 7.4e-06 24.9 0.2 2.4e-05 23.2 0.2 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 GAP90680.1 - 0.00052 19.8 3.8 0.00055 19.7 1.9 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAP90680.1 - 0.0074 15.5 0.2 1.3 8.1 0.0 2.7 3 0 0 3 3 3 2 Prolyl oligopeptidase family AXE1 PF05448.7 GAP90680.1 - 0.19 10.1 0.1 0.31 9.4 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Zn_clus PF00172.13 GAP90681.1 - 3.4e-05 23.6 8.4 3.4e-05 23.6 5.8 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Terpene_synth_C PF03936.11 GAP90682.1 - 6e-19 68.3 1.6 8.8e-19 67.7 1.1 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.17 GAP90683.1 - 2.1e-38 132.0 0.0 2.8e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_21 PF05050.7 GAP90683.1 - 9.4e-21 74.4 0.0 2.7e-20 72.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase FkbM domain Methyltransf_18 PF12847.2 GAP90683.1 - 8.5e-07 29.5 0.0 3e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain V_cholerae_RfbT PF05575.6 GAP90683.1 - 0.015 14.3 0.0 0.14 11.2 0.0 2.0 2 0 0 2 2 2 0 Vibrio cholerae RfbT protein Met_10 PF02475.11 GAP90683.1 - 0.048 13.2 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein UDPGT PF00201.13 GAP90684.1 - 0.00083 18.0 0.0 0.0014 17.3 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase p450 PF00067.17 GAP90685.1 - 8.8e-46 156.3 0.0 1.4e-45 155.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 SnoaL_2 PF12680.2 GAP90686.1 - 0.078 13.3 0.0 0.094 13.1 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain p450 PF00067.17 GAP90687.1 - 3.5e-61 207.1 0.0 4.3e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 GAP90688.1 - 1.2e-57 195.4 0.0 1.8e-57 194.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ASFV_J13L PF05568.6 GAP90689.1 - 0.0038 16.7 1.9 0.0081 15.7 1.3 1.6 1 0 0 1 1 1 1 African swine fever virus J13L protein AAA_33 PF13671.1 GAP90690.1 - 1.1e-14 54.5 0.3 1.6e-14 53.9 0.0 1.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAP90690.1 - 1.8e-08 35.2 0.2 2.5e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAP90690.1 - 3.6e-06 27.2 0.0 6.3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 GAP90690.1 - 0.00018 20.6 0.0 0.00027 20.0 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin CPT PF07931.7 GAP90690.1 - 0.00042 19.9 0.0 0.00076 19.1 0.0 1.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.5 GAP90690.1 - 0.004 16.4 0.0 0.0053 15.9 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Sugar_tr PF00083.19 GAP90691.1 - 1.1e-66 225.2 21.0 1.3e-66 225.0 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP90691.1 - 1.5e-20 73.2 37.1 4.4e-19 68.3 24.8 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_43 PF04616.9 GAP90692.1 - 5.1e-11 42.1 4.1 6e-10 38.6 0.9 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 adh_short PF00106.20 GAP90693.1 - 4.2e-24 85.3 1.1 6.6e-24 84.7 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP90693.1 - 3.5e-15 56.4 0.1 4.8e-15 55.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP90693.1 - 7.3e-06 25.7 0.3 1.1e-05 25.2 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAP90693.1 - 2.7e-05 23.6 0.8 0.00014 21.4 0.5 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 GAP90693.1 - 7.6e-05 21.9 0.0 0.00011 21.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.8 GAP90693.1 - 0.00013 21.3 0.0 0.0065 15.7 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 GAP90693.1 - 0.00017 21.6 0.1 0.00036 20.5 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding Abhydrolase_6 PF12697.2 GAP90694.1 - 4.4e-15 56.1 1.1 5.6e-15 55.8 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP90694.1 - 2.7e-05 23.9 0.0 4.9e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 GAP90694.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Acyl-CoA_dh_1 PF00441.19 GAP90695.1 - 1.6e-40 138.6 0.6 2.3e-40 138.1 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 GAP90695.1 - 1.9e-20 72.1 0.3 3.8e-20 71.1 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 GAP90695.1 - 2.8e-19 68.7 0.3 4.9e-19 67.9 0.2 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 GAP90695.1 - 7.9e-19 68.3 0.0 1.8e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 GAP90695.1 - 4.6e-08 33.4 0.0 9.1e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DNA_pol_B_exo1 PF03104.14 GAP90696.1 - 0.15 10.8 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase family B, exonuclease domain YL1 PF05764.8 GAP90697.1 - 0.007 16.0 0.0 0.0083 15.7 0.0 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Sporozoite_P67 PF05642.6 GAP90697.1 - 0.22 9.3 2.9 0.39 8.5 2.0 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.12 GAP90697.1 - 0.44 10.3 14.1 0.79 9.4 9.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein PBP1_TM PF14812.1 GAP90697.1 - 1.9 8.8 11.7 3.3 8.0 8.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_transf_20 PF00982.16 GAP90698.1 - 6.8e-197 654.6 0.0 7.8e-197 654.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 GAP90698.1 - 0.067 12.6 0.1 0.28 10.6 0.0 2.0 2 0 0 2 2 2 0 Starch synthase catalytic domain Tyrosinase PF00264.15 GAP90699.1 - 6.8e-34 117.9 6.6 1.6e-33 116.7 4.0 1.9 2 0 0 2 2 2 1 Common central domain of tyrosinase DUF4139 PF13598.1 GAP90699.1 - 0.092 12.0 0.4 0.13 11.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) AF0941-like PF14591.1 GAP90699.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 AF0941-like DUF605 PF04652.11 GAP90700.1 - 2.9 7.2 15.3 3.2 7.0 10.6 1.1 1 0 0 1 1 1 0 Vta1 like PSII_BNR PF14870.1 GAP90701.1 - 5.9e-08 32.0 6.2 0.043 12.8 0.0 4.5 2 2 3 5 5 5 3 Photosynthesis system II assembly factor YCF48 BNR PF02012.15 GAP90701.1 - 1.2e-07 30.4 15.6 0.65 10.0 0.1 6.6 5 1 1 6 6 6 5 BNR/Asp-box repeat Bd3614_N PF14442.1 GAP90701.1 - 0.027 14.4 2.4 0.18 11.8 0.9 2.2 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal FAD_binding_3 PF01494.14 GAP90703.1 - 6.6e-16 58.3 0.6 5.6e-12 45.3 0.3 3.0 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAP90703.1 - 0.0047 16.9 0.1 0.032 14.2 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Glyco_hydro_61 PF03443.9 GAP90704.1 - 1.9e-60 204.4 0.2 1.9e-60 204.4 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Aa_trans PF01490.13 GAP90705.1 - 3.6e-77 259.5 29.7 4.3e-77 259.3 20.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease PF00324.16 GAP90706.1 - 2.9e-102 342.5 46.9 3.5e-102 342.1 32.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAP90706.1 - 1.1e-25 90.1 48.5 1.3e-25 89.8 33.6 1.1 1 0 0 1 1 1 1 Amino acid permease W2 PF02020.13 GAP90707.1 - 1.3e-18 66.6 0.5 3.3e-18 65.3 0.4 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 GAP90707.1 - 6.1e-13 47.6 8.1 1.5e-06 27.3 1.2 3.6 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 GAP90707.1 - 6.8e-09 35.1 6.3 0.0016 17.9 2.2 3.3 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 GAP90707.1 - 0.0027 16.3 2.0 0.17 10.3 0.1 2.3 1 1 1 2 2 2 2 L-fucokinase NTP_transferase PF00483.18 GAP90707.1 - 0.0041 16.4 0.0 0.0076 15.5 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 GAP90707.1 - 0.0066 16.5 0.0 0.02 14.9 0.0 1.8 1 0 0 1 1 1 1 MobA-like NTP transferase domain Toxin_53 PF15532.1 GAP90707.1 - 0.014 15.6 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 Putative toxin 53 DUF1385 PF07136.6 GAP90707.1 - 0.1 11.6 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) HCV_capsid PF01543.12 GAP90708.1 - 0.089 12.7 0.2 0.87 9.5 0.0 2.0 2 0 0 2 2 2 0 Hepatitis C virus capsid protein HSF_DNA-bind PF00447.12 GAP90709.1 - 1.2e-37 128.2 0.5 2.3e-37 127.3 0.3 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 GAP90709.1 - 2.6e-23 82.1 0.1 5.7e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain DUF972 PF06156.8 GAP90709.1 - 0.08 13.2 0.5 0.17 12.2 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) IncA PF04156.9 GAP90709.1 - 0.11 12.0 2.2 0.17 11.4 1.5 1.2 1 0 0 1 1 1 0 IncA protein RCC1 PF00415.13 GAP90711.1 - 2.4e-30 104.4 2.6 2.2e-05 24.5 0.0 6.8 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAP90711.1 - 1.6e-12 46.6 37.9 1.3e-10 40.6 0.0 8.1 8 2 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat Sec34 PF04136.10 GAP90712.1 - 4e-29 101.3 0.1 1e-28 99.9 0.0 1.7 1 0 0 1 1 1 1 Sec34-like family Methyltransf_11 PF08241.7 GAP90713.1 - 1.2e-18 67.3 0.0 1.9e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP90713.1 - 1.7e-17 63.6 0.0 4.2e-17 62.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP90713.1 - 1.6e-16 60.2 0.0 4.6e-16 58.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP90713.1 - 1.3e-12 48.2 0.0 2.2e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP90713.1 - 4.3e-11 42.8 0.5 1.1e-10 41.5 0.3 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP90713.1 - 2.1e-10 40.9 0.0 5.3e-10 39.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP90713.1 - 7.8e-09 35.8 0.0 1.4e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 GAP90713.1 - 1.2e-07 31.1 0.0 1.7e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 GAP90713.1 - 7.6e-07 28.9 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 GAP90713.1 - 1.4e-06 27.8 0.0 3.1e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.13 GAP90713.1 - 4.5e-06 25.9 0.0 3.2e-05 23.1 0.0 2.1 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 GAP90713.1 - 3.5e-05 23.2 0.1 6.3e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 GAP90713.1 - 4.6e-05 22.2 0.0 0.00027 19.7 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1698) TPMT PF05724.6 GAP90713.1 - 0.00027 20.4 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) PCMT PF01135.14 GAP90713.1 - 0.00097 18.7 0.1 0.0024 17.4 0.1 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Daxx PF03344.10 GAP90713.1 - 0.0026 16.3 0.3 0.0034 15.9 0.2 1.1 1 0 0 1 1 1 1 Daxx Family TehB PF03848.9 GAP90713.1 - 0.011 14.9 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_8 PF05148.10 GAP90713.1 - 0.044 13.3 0.0 3 7.4 0.0 2.2 2 0 0 2 2 2 0 Hypothetical methyltransferase BLVR PF06375.6 GAP90713.1 - 0.38 10.5 4.2 0.67 9.7 2.9 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Hydrophobin_2 PF06766.6 GAP90714.1 - 0.12 12.0 5.0 0.5 10.0 3.4 1.9 1 1 0 1 1 1 0 Fungal hydrophobin But2 PF09792.4 GAP90715.1 - 4.8e-30 104.1 1.7 6e-30 103.8 1.2 1.1 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Ferric_reduct PF01794.14 GAP90716.1 - 7.5e-15 55.1 9.0 7.5e-15 55.1 6.2 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 GAP90716.1 - 6.3e-06 26.0 0.0 2.8e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 GAP90716.1 - 0.016 15.1 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Ank_2 PF12796.2 GAP90717.1 - 4.6e-52 174.3 0.8 5.9e-12 45.7 0.1 5.9 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAP90717.1 - 3.2e-26 91.2 4.4 1.1e-06 28.9 0.2 7.4 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.25 GAP90717.1 - 2.6e-24 83.7 15.7 0.01 15.6 0.1 10.6 10 0 0 10 10 10 7 Ankyrin repeat Ank_3 PF13606.1 GAP90717.1 - 2.9e-21 73.4 12.1 0.037 14.2 0.0 9.5 10 0 0 10 10 9 6 Ankyrin repeat Ank_5 PF13857.1 GAP90717.1 - 9.2e-20 70.2 6.2 0.0066 16.6 0.1 9.0 6 3 3 9 9 8 5 Ankyrin repeats (many copies) NACHT PF05729.7 GAP90717.1 - 6.2e-05 22.7 0.0 0.0004 20.0 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 GAP90717.1 - 0.0004 20.5 0.0 0.0019 18.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain Abhydrolase_6 PF12697.2 GAP90717.1 - 0.00053 19.9 0.1 0.002 18.0 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA_16 PF13191.1 GAP90717.1 - 0.002 18.1 0.0 0.0063 16.5 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 GAP90717.1 - 0.05 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 GAP90717.1 - 0.087 12.2 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF676 PF05057.9 GAP90717.1 - 0.13 11.4 0.0 0.32 10.2 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2791 PF10923.3 GAP90717.1 - 0.14 10.6 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) PIF1 PF05970.9 GAP90717.1 - 0.23 10.3 0.0 0.44 9.4 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase DUF2075 PF09848.4 GAP90717.1 - 0.25 10.2 0.0 0.39 9.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Glyco_hydro_18 PF00704.23 GAP90718.1 - 2e-52 178.7 0.6 3.3e-52 178.0 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 GAP90718.1 - 2.6e-18 65.6 0.2 6.5e-06 25.9 0.1 3.5 3 0 0 3 3 3 3 LysM domain Chitin_bind_1 PF00187.14 GAP90718.1 - 3.1e-05 23.8 2.4 3.1e-05 23.8 1.6 4.1 3 0 0 3 3 3 1 Chitin recognition protein AAA_18 PF13238.1 GAP90719.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain WSC PF01822.14 GAP90721.1 - 6.3e-13 48.4 8.0 6.3e-13 48.4 5.6 3.7 3 1 0 3 3 3 1 WSC domain PAN_4 PF14295.1 GAP90721.1 - 0.0081 15.8 0.3 0.0081 15.8 0.2 4.1 4 0 0 4 4 4 1 PAN domain Chal_sti_synt_N PF00195.14 GAP90722.1 - 3.9e-26 91.7 0.0 5.5e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.10 GAP90722.1 - 3.5e-17 62.7 0.0 8.3e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.5 GAP90722.1 - 3.4e-07 30.1 0.3 1.4e-06 28.1 0.0 2.2 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FAE1_CUT1_RppA PF08392.7 GAP90722.1 - 2e-06 27.1 0.0 2.9e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III PF08545.5 GAP90722.1 - 3e-05 23.5 1.7 0.00015 21.3 1.0 2.3 1 1 1 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Pyr_redox PF00070.22 GAP90723.1 - 0.0029 17.9 1.1 0.0066 16.8 0.8 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP90723.1 - 0.0048 16.9 1.8 0.017 15.1 1.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 GAP90723.1 - 0.1 11.6 8.1 0.33 9.9 2.0 2.9 2 1 1 3 3 3 0 FAD binding domain Pyr_redox_2 PF07992.9 GAP90723.1 - 0.11 12.4 0.2 0.26 11.1 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase eIF2A PF08662.6 GAP90724.1 - 1.4e-76 256.5 0.0 5e-76 254.7 0.0 2.0 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 GAP90724.1 - 6.4e-05 22.6 2.1 4.9 7.2 0.0 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Dermcidin PF15291.1 GAP90724.1 - 0.84 9.8 9.9 0.19 11.9 1.3 2.4 2 0 0 2 2 2 0 Dermcidin, antibiotic peptide HET PF06985.6 GAP90725.1 - 5.1e-25 88.2 0.0 8.8e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA_10 PF12846.2 GAP90726.1 - 3.5e-10 39.8 0.0 1.4e-09 37.8 0.0 1.9 1 1 0 1 1 1 1 AAA-like domain Zot PF05707.7 GAP90726.1 - 0.0003 20.2 0.0 0.0027 17.2 0.0 2.2 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) DUF87 PF01935.12 GAP90726.1 - 0.0011 18.8 0.1 0.0055 16.5 0.0 2.0 2 1 0 2 2 2 1 Domain of unknown function DUF87 Zeta_toxin PF06414.7 GAP90726.1 - 0.0045 16.0 0.0 0.0078 15.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 GAP90726.1 - 0.1 12.7 0.2 1.9 8.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain NAD_binding_10 PF13460.1 GAP90727.1 - 7.3e-07 29.3 0.0 9.2e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 GAP90727.1 - 0.0012 17.8 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 GAP90727.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.5 2 0 0 2 2 2 0 short chain dehydrogenase DUF4547 PF15080.1 GAP90727.1 - 0.15 11.4 0.0 2.9 7.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4547) Granulin PF00396.13 GAP90728.1 - 0.066 13.3 4.9 0.2 11.7 0.8 2.4 1 1 1 2 2 2 0 Granulin Glyco_hydro_2_C PF02836.12 GAP90729.1 - 3.5e-103 344.6 0.1 4.8e-103 344.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 GAP90729.1 - 2.3e-52 177.7 0.0 4.8e-52 176.6 0.0 1.6 1 1 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 GAP90729.1 - 5.1e-52 175.7 0.1 9.8e-52 174.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 GAP90729.1 - 8.2e-14 51.9 0.0 2.2e-13 50.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 GAP90729.1 - 0.002 18.3 0.1 0.0071 16.5 0.0 1.9 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain FAD_binding_3 PF01494.14 GAP90730.1 - 2.9e-06 26.5 0.0 4.4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain GET2 PF08690.5 GAP90730.1 - 3 7.0 6.6 13 4.9 3.2 2.5 1 1 1 2 2 2 0 GET complex subunit GET2 NAD_binding_10 PF13460.1 GAP90731.1 - 0.039 13.9 0.0 2.1 8.3 0.0 2.8 2 1 0 2 2 2 0 NADH(P)-binding Epimerase PF01370.16 GAP90731.1 - 0.12 11.7 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Abhydrolase_6 PF12697.2 GAP90732.1 - 0.00012 22.0 1.7 0.00045 20.1 0.5 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family AAA_16 PF13191.1 GAP90732.1 - 0.0014 18.6 0.0 0.0034 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain DUF676 PF05057.9 GAP90732.1 - 0.0051 16.1 0.1 0.024 13.9 0.0 2.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 GAP90732.1 - 0.0066 16.0 0.1 0.12 11.9 0.0 2.4 3 0 0 3 3 3 1 PGAP1-like protein AAA_22 PF13401.1 GAP90732.1 - 0.01 15.9 0.0 0.034 14.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 GAP90732.1 - 0.013 15.1 0.1 0.027 14.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 GAP90732.1 - 0.029 13.8 0.0 0.069 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF900 PF05990.7 GAP90732.1 - 0.17 11.1 0.6 0.61 9.3 0.0 2.1 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF900) DUF2305 PF10230.4 GAP90732.1 - 0.26 10.6 0.0 0.49 9.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Microtub_assoc PF07989.6 GAP90733.1 - 1.9e-18 66.0 7.2 1.9e-18 66.0 5.0 8.0 10 0 0 10 10 10 1 Microtubule associated Mto2_bdg PF12808.2 GAP90733.1 - 1e-11 44.7 15.2 1e-11 44.7 10.6 9.4 11 0 0 11 11 11 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Potassium_chann PF11404.3 GAP90735.1 - 4.7 7.0 10.3 3.7 7.4 1.7 3.1 3 0 0 3 3 3 0 Potassium voltage-gated channel CUE PF02845.11 GAP90736.1 - 8.9e-09 34.6 0.4 5.8e-08 32.0 0.1 2.3 2 0 0 2 2 2 1 CUE domain API5 PF05918.6 GAP90736.1 - 1.7 7.0 5.1 13 4.1 3.4 2.1 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) Ribosomal_S10 PF00338.17 GAP90737.1 - 1.6e-27 95.1 0.4 1.9e-27 94.9 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e zf-CCCH PF00642.19 GAP90738.1 - 0.0023 17.5 2.3 0.0046 16.5 1.6 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 GAP90738.1 - 0.059 13.3 1.1 0.2 11.7 0.7 1.9 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Cellulase PF00150.13 GAP90739.1 - 3.2e-17 62.6 5.2 2.2e-16 59.8 3.6 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) p450 PF00067.17 GAP90740.1 - 9.6e-58 195.8 0.0 1.3e-57 195.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SKG6 PF08693.5 GAP90741.1 - 0.00075 18.7 0.1 0.0011 18.2 0.1 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1191 PF06697.7 GAP90741.1 - 0.013 14.3 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF4366 PF14283.1 GAP90741.1 - 0.037 13.4 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) EphA2_TM PF14575.1 GAP90741.1 - 0.12 12.8 0.0 0.21 11.9 0.0 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain NMT1_2 PF13379.1 GAP90742.1 - 0.00011 21.7 0.3 0.00017 21.0 0.2 1.2 1 0 0 1 1 1 1 NMT1-like family SPAN PF02510.9 GAP90742.1 - 0.064 12.3 2.8 0.13 11.2 2.0 1.5 1 0 0 1 1 1 0 Surface presentation of antigens protein TPR_11 PF13414.1 GAP90743.1 - 7.7e-44 147.1 43.1 2.4e-06 27.1 0.1 12.6 11 2 1 12 12 12 10 TPR repeat TPR_1 PF00515.23 GAP90743.1 - 5.4e-27 92.2 19.6 0.0073 15.8 0.0 13.8 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_2 PF07719.12 GAP90743.1 - 5.6e-27 91.4 39.6 0.013 15.4 0.0 15.9 17 0 0 17 17 15 8 Tetratricopeptide repeat TPR_17 PF13431.1 GAP90743.1 - 4.9e-25 85.5 11.1 0.06 13.5 0.0 14.1 15 0 0 15 15 14 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAP90743.1 - 6.9e-24 82.1 32.0 0.0002 21.6 0.0 15.2 10 5 6 16 16 16 5 Tetratricopeptide repeat TPR_16 PF13432.1 GAP90743.1 - 1.8e-22 79.4 57.9 5.2e-05 23.7 0.7 13.7 10 5 7 17 17 17 7 Tetratricopeptide repeat TPR_19 PF14559.1 GAP90743.1 - 7.2e-20 71.1 29.5 0.0012 19.1 0.0 10.2 9 2 1 10 10 8 6 Tetratricopeptide repeat TPR_12 PF13424.1 GAP90743.1 - 8.6e-17 60.8 50.0 6.3e-05 22.8 0.0 12.1 9 3 6 15 15 15 7 Tetratricopeptide repeat TPR_8 PF13181.1 GAP90743.1 - 2.9e-16 57.9 17.6 0.028 14.1 0.0 13.1 13 1 1 14 14 13 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAP90743.1 - 2.6e-09 36.1 24.0 0.083 12.7 0.0 12.2 12 2 1 13 13 13 4 Tetratricopeptide repeat TPR_9 PF13371.1 GAP90743.1 - 6.7e-07 29.0 16.5 0.032 14.0 1.1 7.7 7 2 1 8 8 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 GAP90743.1 - 0.005 17.2 34.1 0.012 16.0 0.0 12.8 17 0 0 17 17 13 1 Tetratricopeptide repeat PPTA PF01239.17 GAP90743.1 - 0.0081 15.4 0.1 0.93 8.9 0.0 3.3 3 0 0 3 3 3 1 Protein prenyltransferase alpha subunit repeat Coatomer_WDAD PF04053.9 GAP90743.1 - 0.014 14.2 0.0 0.03 13.1 0.0 1.5 1 0 0 1 1 1 0 Coatomer WD associated region TPR_10 PF13374.1 GAP90743.1 - 0.12 12.3 8.6 2.5 8.1 0.0 5.7 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 GAP90743.1 - 3.9 8.1 0.0 3.9 8.1 0.0 8.4 9 0 0 9 9 7 0 Tetratricopeptide repeat Cellulase PF00150.13 GAP90744.1 - 1e-12 47.8 0.4 4.6e-08 32.5 0.0 2.6 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 GAP90744.1 - 0.00086 18.5 0.4 0.1 11.6 0.0 2.1 2 0 0 2 2 2 2 Beta-galactosidase Pkinase PF00069.20 GAP90745.1 - 8.2e-66 221.8 0.0 1.3e-65 221.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP90745.1 - 2e-47 161.4 0.0 2.9e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP90745.1 - 2.3e-09 36.6 0.0 2.4e-07 30.0 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 GAP90745.1 - 0.023 13.7 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CFEM PF05730.6 GAP90746.1 - 2.3e-13 49.7 11.2 3.5e-13 49.1 7.8 1.3 1 0 0 1 1 1 1 CFEM domain ACC_epsilon PF13822.1 GAP90746.1 - 0.037 14.3 0.8 0.037 14.3 0.6 1.7 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Ribonuclease_T2 PF00445.13 GAP90747.1 - 2.8e-41 141.2 0.4 3.8e-41 140.7 0.3 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family tRNA-synt_2 PF00152.15 GAP90748.1 - 7.9e-72 241.8 0.0 1.2e-71 241.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 GAP90748.1 - 3.2e-09 36.5 0.0 7e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 GAP90748.1 - 0.028 13.6 0.0 0.68 9.0 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Catalase PF00199.14 GAP90749.1 - 5.1e-156 519.1 0.1 7.7e-156 518.5 0.1 1.3 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 GAP90749.1 - 5.3e-14 51.8 0.2 1.1e-13 50.8 0.2 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Alpha-amylase PF00128.19 GAP90751.1 - 2.3e-78 263.7 0.7 2.7e-57 194.5 0.6 2.1 1 1 1 2 2 2 2 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 GAP90751.1 - 0.0011 18.0 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Zn_clus PF00172.13 GAP90753.1 - 3.1e-07 30.1 12.6 3.1e-07 30.1 8.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PQ-loop PF04193.9 GAP90755.1 - 5.6e-05 22.6 0.0 0.00024 20.5 0.0 2.2 1 0 0 1 1 1 1 PQ loop repeat DUF1705 PF08019.7 GAP90755.1 - 0.029 13.8 0.4 0.029 13.8 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1705) DUF1772 PF08592.6 GAP90755.1 - 0.28 10.9 12.7 0.053 13.2 1.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) 7TMR-DISM_7TM PF07695.6 GAP90755.1 - 0.98 9.0 17.7 0.095 12.3 7.0 2.5 1 1 1 2 2 2 0 7TM diverse intracellular signalling Chromate_transp PF02417.10 GAP90755.1 - 4.6 6.8 15.1 0.46 10.0 7.1 1.8 2 0 0 2 2 2 0 Chromate transporter WBP-1 PF11669.3 GAP90755.1 - 8.8 6.4 7.9 2 8.5 1.7 2.4 3 0 0 3 3 3 0 WW domain-binding protein 1 TBCC PF07986.7 GAP90757.1 - 8.2e-33 112.3 0.1 1.2e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C iPGM_N PF06415.8 GAP90758.1 - 2.7e-74 249.2 0.0 3.6e-74 248.8 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.13 GAP90758.1 - 1e-69 234.7 0.0 1.2e-69 234.5 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.17 GAP90758.1 - 2.7e-05 23.6 0.0 0.0002 20.8 0.0 2.1 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 GAP90758.1 - 0.0011 18.2 0.0 0.021 14.0 0.0 2.8 2 1 0 2 2 2 1 Sulfatase PCI_Csn8 PF10075.4 GAP90759.1 - 8.5e-38 129.3 0.0 1.2e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 GAP90759.1 - 8.3e-19 67.9 0.0 1.1e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PDCD2_C PF04194.8 GAP90760.1 - 8.1e-48 162.1 0.0 2.3e-47 160.6 0.0 1.7 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain Pox_Ag35 PF03286.9 GAP90761.1 - 0.073 12.5 0.3 0.098 12.1 0.2 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FBP PF07299.6 GAP90761.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein (FBP) SpoVR PF04293.8 GAP90761.1 - 0.21 9.9 0.4 0.31 9.3 0.3 1.1 1 0 0 1 1 1 0 SpoVR like protein DUF1996 PF09362.5 GAP90764.1 - 1e-87 293.7 0.8 1.2e-87 293.4 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Syndecan PF01034.15 GAP90765.1 - 0.073 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.5 GAP90765.1 - 0.21 10.9 0.1 0.56 9.5 0.0 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.1 GAP90765.1 - 0.28 11.6 3.9 0.49 10.8 0.0 3.2 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain 2-Hacid_dh_C PF02826.14 GAP90766.1 - 1.2e-37 128.7 0.0 1.7e-37 128.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAP90766.1 - 1.9e-11 43.5 0.0 2.6e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 GAP90766.1 - 6.4e-08 32.5 0.0 1.1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 GAP90766.1 - 0.0013 19.1 0.1 0.003 17.9 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 GAP90766.1 - 0.0028 17.3 0.5 0.0077 15.9 0.1 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 GAP90766.1 - 0.023 14.6 0.0 0.05 13.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_C PF03720.10 GAP90766.1 - 0.039 14.1 0.0 0.076 13.1 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Semialdhyde_dh PF01118.19 GAP90766.1 - 0.073 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain HET PF06985.6 GAP90768.1 - 1.1e-21 77.4 0.1 2.2e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4518 PF15008.1 GAP90768.1 - 0.066 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) DUF721 PF05258.7 GAP90769.1 - 0.025 14.7 0.2 0.057 13.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF721) Ribosomal_60s PF00428.14 GAP90769.1 - 0.076 13.4 0.8 0.15 12.4 0.6 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein 4HBT PF03061.17 GAP90770.1 - 3.1e-10 40.0 0.0 5.7e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily F-box-like PF12937.2 GAP90770.1 - 1.1e-06 28.2 1.4 2.5e-06 27.1 1.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAP90770.1 - 0.0013 18.3 1.0 0.0083 15.7 0.5 2.4 2 0 0 2 2 2 1 F-box domain Peptidase_S8 PF00082.17 GAP90771.1 - 0.037 13.1 0.3 0.19 10.8 0.2 1.9 1 1 0 1 1 1 0 Subtilase family DUF4355 PF14265.1 GAP90772.1 - 0.064 13.2 7.8 0.16 11.9 5.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Asp_Glu_race_2 PF14669.1 GAP90772.1 - 0.072 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative aspartate racemase DUF4140 PF13600.1 GAP90772.1 - 0.26 11.7 4.6 0.3 11.5 0.5 2.6 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) FAD_binding_6 PF00970.19 GAP90774.1 - 1.3e-06 28.4 0.0 5.7e-06 26.3 0.0 2.1 3 0 0 3 3 3 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 GAP90774.1 - 2.4e-06 28.0 0.0 4.7e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 GAP90774.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Spo7_2_N PF15407.1 GAP90778.1 - 0.015 14.7 0.1 0.026 13.9 0.1 1.4 1 0 0 1 1 1 0 Sporulation protein family 7 Ribosomal_L22 PF00237.14 GAP90781.1 - 1.6e-34 118.0 0.1 2.4e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Fibrillarin PF01269.12 GAP90782.1 - 2.8e-86 288.1 0.0 1.4e-85 285.8 0.0 1.8 1 1 0 1 1 1 1 Fibrillarin Nucleoplasmin PF03066.10 GAP90783.1 - 0.0037 16.7 0.5 0.0041 16.6 0.4 1.1 1 0 0 1 1 1 1 Nucleoplasmin RXT2_N PF08595.6 GAP90783.1 - 0.038 13.8 2.2 0.046 13.5 1.5 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.5 GAP90783.1 - 0.05 13.8 6.0 0.064 13.5 4.1 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Methyltransf_16 PF10294.4 GAP90783.1 - 0.076 12.4 0.0 0.077 12.4 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase FAM176 PF14851.1 GAP90783.1 - 0.12 12.0 1.7 0.16 11.6 1.2 1.2 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.1 GAP90783.1 - 0.24 11.7 8.3 0.31 11.3 5.7 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.1 GAP90783.1 - 0.4 10.8 3.8 0.52 10.4 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Sigma70_ner PF04546.8 GAP90783.1 - 0.66 9.5 5.0 0.78 9.3 3.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 GAP90783.1 - 1.9 7.6 5.9 2.3 7.4 4.1 1.1 1 0 0 1 1 1 0 NOA36 protein Tom22 PF04281.8 GAP90783.1 - 2.2 7.8 5.0 2.6 7.5 3.5 1.1 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 zf-C2H2_4 PF13894.1 GAP90784.1 - 6e-05 23.1 16.8 0.13 12.7 0.0 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 GAP90784.1 - 0.00051 20.2 20.4 0.5 10.8 0.8 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 GAP90784.1 - 0.015 15.1 4.6 0.1 12.5 0.4 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger BBS2_C PF14782.1 GAP90785.1 - 0.064 11.8 0.9 0.064 11.8 0.6 1.0 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal PAS_9 PF13426.1 GAP90787.1 - 1.5e-13 51.0 0.0 6.1e-13 49.0 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 GAP90787.1 - 0.072 13.1 0.6 2 8.4 0.0 3.2 3 0 0 3 3 3 0 PAS fold WD40 PF00400.27 GAP90788.1 - 1.5e-33 113.4 9.7 1.5e-06 27.8 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 GAP90788.1 - 4.3e-08 33.0 0.1 0.0027 17.4 0.0 3.1 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A DUF2838 PF10998.3 GAP90789.1 - 2.4e-45 152.9 11.2 2.4e-45 152.9 7.7 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Atg14 PF10186.4 GAP90789.1 - 0.18 10.6 1.7 0.28 10.0 1.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF349 PF03993.7 GAP90789.1 - 0.2 11.8 4.0 0.54 10.4 2.8 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) AAA_27 PF13514.1 GAP90789.1 - 0.34 8.5 3.7 0.47 8.0 2.5 1.1 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 GAP90789.1 - 0.58 7.4 3.6 0.82 6.9 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SMC_N PF02463.14 GAP90790.1 - 8.5e-42 142.8 0.2 2e-41 141.6 0.2 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 GAP90790.1 - 4.2e-27 94.4 0.0 4.3e-26 91.2 0.0 2.9 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain Reo_sigmaC PF04582.7 GAP90790.1 - 3.2e-06 26.5 22.0 0.0027 16.9 0.8 4.7 4 1 0 5 5 5 3 Reovirus sigma C capsid protein Spc7 PF08317.6 GAP90790.1 - 1.5e-05 23.8 33.0 0.00027 19.7 9.0 6.1 4 1 2 6 6 6 3 Spc7 kinetochore protein DUF3584 PF12128.3 GAP90790.1 - 9.7e-05 19.9 14.3 9.7e-05 19.9 9.9 5.8 4 1 0 5 5 5 2 Protein of unknown function (DUF3584) AAA_21 PF13304.1 GAP90790.1 - 0.00015 21.8 0.2 0.00015 21.8 0.1 3.3 3 0 0 3 3 3 1 AAA domain ADIP PF11559.3 GAP90790.1 - 0.0023 17.8 12.2 0.0023 17.8 8.5 7.6 4 2 3 7 7 7 3 Afadin- and alpha -actinin-Binding SbcCD_C PF13558.1 GAP90790.1 - 0.0036 17.1 0.0 0.02 14.8 0.0 2.4 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit FliJ PF02050.11 GAP90790.1 - 0.0061 16.6 8.1 0.0061 16.6 5.6 8.6 4 3 4 8 8 8 2 Flagellar FliJ protein AAA_13 PF13166.1 GAP90790.1 - 4.5 5.5 98.8 0.043 12.2 16.9 5.4 3 2 3 6 6 6 0 AAA domain TFIIE_alpha PF02002.12 GAP90791.1 - 8.3e-15 54.1 0.1 1.7e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit DNA_pol_lambd_f PF10391.4 GAP90792.1 - 6.1e-21 73.7 0.3 1.2e-20 72.8 0.2 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.1 GAP90792.1 - 1e-19 70.6 0.0 2.1e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 GAP90792.1 - 1.9e-18 65.8 0.0 3.8e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 GAP90792.1 - 4e-10 39.7 0.0 9.8e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.1 GAP90792.1 - 0.0032 17.6 0.0 0.16 12.1 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 GAP90792.1 - 0.098 12.9 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain Abhydrolase_6 PF12697.2 GAP90793.1 - 1.6e-19 70.7 9.2 1.6e-19 70.7 6.4 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP90793.1 - 6e-16 58.5 0.1 9.6e-16 57.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAP90793.1 - 1.9e-13 50.0 0.1 1.3e-12 47.3 0.2 2.1 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 GAP90793.1 - 4.8e-05 22.6 0.1 0.063 12.4 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 GAP90793.1 - 0.0001 21.9 1.1 0.00013 21.5 0.8 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 GAP90793.1 - 0.028 14.0 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) K_channel_TID PF07941.6 GAP90793.1 - 0.075 13.2 2.9 0.22 11.7 2.0 1.8 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DUF1749 PF08538.5 GAP90793.1 - 0.13 11.1 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) BCA_ABC_TP_C PF12399.3 GAP90793.1 - 0.66 9.7 3.4 0.75 9.5 1.1 2.2 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter Clathrin_lg_ch PF01086.12 GAP90795.1 - 3.5e-66 223.3 2.6 3.9e-66 223.1 1.8 1.0 1 0 0 1 1 1 1 Clathrin light chain rve_3 PF13683.1 GAP90795.1 - 0.16 11.5 0.3 0.37 10.3 0.2 1.6 1 0 0 1 1 1 0 Integrase core domain PPR_3 PF13812.1 GAP90796.1 - 0.0013 18.8 0.0 9.6 6.7 0.0 4.6 4 0 0 4 4 4 2 Pentatricopeptide repeat domain SNARE PF05739.14 GAP90797.1 - 1.8e-18 65.9 2.5 1.8e-18 65.9 1.7 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 GAP90797.1 - 1.2e-11 44.7 2.8 8.1e-11 42.0 0.2 2.3 2 0 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 GAP90797.1 - 0.0023 17.4 6.8 0.22 11.0 0.4 2.6 3 0 0 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain YhhN PF07947.9 GAP90797.1 - 0.07 12.4 0.1 0.1 11.9 0.1 1.1 1 0 0 1 1 1 0 YhhN-like protein PrgI PF12666.2 GAP90797.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 PrgI family protein EF-hand_1 PF00036.27 GAP90798.1 - 2.8e-41 135.7 12.8 1.1e-09 36.9 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 GAP90798.1 - 5.2e-37 125.8 5.3 2.3e-20 72.4 0.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 GAP90798.1 - 5.6e-35 118.7 11.8 5.5e-16 57.9 0.4 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 GAP90798.1 - 1.2e-30 102.6 8.0 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 GAP90798.1 - 5.2e-26 88.7 9.7 1.4e-06 27.3 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 GAP90798.1 - 5.7e-16 58.1 0.2 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 GAP90798.1 - 5.1e-09 35.8 1.7 0.0012 18.5 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 GAP90798.1 - 1.1e-08 35.1 0.1 0.0027 17.7 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 GAP90798.1 - 2.3e-08 33.5 0.2 0.022 14.3 0.0 3.3 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 GAP90798.1 - 4.2e-07 29.8 2.1 4.3e-06 26.6 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 GAP90798.1 - 0.00011 21.9 0.4 0.3 10.8 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 GAP90798.1 - 0.00021 20.8 0.2 0.072 12.6 0.0 2.8 1 1 1 3 3 3 1 Caleosin related protein RNA_pol_Rpb4 PF03874.11 GAP90798.1 - 0.0021 18.0 0.8 0.96 9.4 0.0 2.6 3 0 0 3 3 3 2 RNA polymerase Rpb4 Tenui_NCP PF04876.7 GAP90798.1 - 0.0024 17.4 0.1 0.12 11.8 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein Toprim_2 PF13155.1 GAP90798.1 - 0.0052 17.0 1.1 2.5 8.4 0.0 2.5 1 1 1 2 2 2 2 Toprim-like DUF3349 PF11829.3 GAP90798.1 - 0.028 14.8 0.5 16 6.0 0.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 GAP90798.1 - 0.12 12.0 2.5 0.69 9.6 0.1 3.1 1 1 3 4 4 4 0 EF hand RloB PF13707.1 GAP90798.1 - 0.27 10.8 3.9 0.78 9.3 0.8 2.3 1 1 1 2 2 2 0 RloB-like protein PB1 PF00564.19 GAP90798.1 - 0.28 10.8 2.6 27 4.5 0.1 3.3 2 1 1 3 3 3 0 PB1 domain ABC_membrane PF00664.18 GAP90799.1 - 1.5e-43 149.2 11.8 1.9e-43 148.8 8.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 GAP90799.1 - 3.7e-34 117.9 0.0 7.5e-34 116.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 GAP90799.1 - 1.3e-05 25.3 0.0 3.9e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 GAP90799.1 - 5.2e-05 23.3 0.2 0.68 9.8 0.0 3.0 2 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 GAP90799.1 - 0.0027 17.1 0.2 0.014 14.8 0.2 2.1 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 GAP90799.1 - 0.0035 16.6 3.2 0.14 11.3 2.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 GAP90799.1 - 0.0056 17.4 0.9 0.0091 16.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_29 PF13555.1 GAP90799.1 - 0.0088 15.5 0.1 0.022 14.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 GAP90799.1 - 0.01 16.0 0.2 0.07 13.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 GAP90799.1 - 0.018 14.9 0.9 0.14 12.0 0.6 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 GAP90799.1 - 0.02 14.3 0.5 0.16 11.3 0.1 2.3 2 0 0 2 2 2 0 AAA-like domain AAA PF00004.24 GAP90799.1 - 0.042 14.0 0.0 0.28 11.3 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 GAP90799.1 - 0.079 12.1 0.0 0.2 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 CTD_bind PF04818.8 GAP90801.1 - 3.9e-20 71.8 0.2 1.1e-19 70.4 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CTK3 PF12243.3 GAP90801.1 - 0.018 14.6 0.0 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Trypan_PARP PF05887.6 GAP90801.1 - 2.4 7.9 16.0 3.8 7.3 11.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Acetyltransf_1 PF00583.19 GAP90804.1 - 6.5e-16 58.1 0.0 9e-16 57.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAP90804.1 - 2.1e-07 30.9 0.0 3.8e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAP90804.1 - 2.3e-07 30.4 0.0 3.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 GAP90804.1 - 6.9e-06 26.0 0.0 1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAP90804.1 - 7.8e-06 25.9 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAP90804.1 - 0.0055 16.5 0.0 0.0093 15.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAP90804.1 - 0.0084 16.0 0.0 0.017 15.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain adh_short PF00106.20 GAP90805.1 - 4e-28 98.4 0.0 5.2e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP90805.1 - 1.5e-15 57.6 0.0 1.9e-15 57.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP90805.1 - 7.3e-12 45.3 0.0 9.5e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.16 GAP90805.1 - 0.034 14.0 0.1 0.041 13.7 0.1 1.3 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF2334 PF10096.4 GAP90805.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) DUF1793 PF08760.6 GAP90806.1 - 5.4e-76 254.2 4.4 1.8e-75 252.4 1.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) RRM_1 PF00076.17 GAP90807.1 - 8.5e-19 66.9 0.0 1.2e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP90807.1 - 5.5e-15 55.1 0.0 8.2e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP90807.1 - 1.2e-10 41.0 0.0 1.9e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec39 PF08314.6 GAP90809.1 - 1.5e-214 714.0 0.0 1.7e-214 713.8 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Ndufs5 PF10200.4 GAP90810.1 - 0.00013 21.9 0.1 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 GAP90810.1 - 0.0075 16.3 0.6 0.017 15.2 0.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.12 GAP90810.1 - 0.048 13.6 1.2 0.049 13.6 0.4 1.4 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb COX17 PF05051.8 GAP90810.1 - 0.086 12.8 0.3 0.17 11.9 0.2 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Tower PF09121.5 GAP90812.1 - 0.51 10.3 4.2 1.6 8.7 0.1 2.4 2 0 0 2 2 2 0 Tower NAD_binding_6 PF08030.7 GAP90813.1 - 0.00045 20.1 0.1 0.51 10.2 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 GAP90813.1 - 0.00082 19.9 0.1 1.6 9.3 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 GAP90813.1 - 0.0076 16.3 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain SSP160 PF06933.6 GAP90813.1 - 0.012 13.6 9.4 0.016 13.2 6.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 GAP90813.1 - 0.32 10.7 8.3 0.61 9.8 5.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Sporozoite_P67 PF05642.6 GAP90813.1 - 0.38 8.5 4.5 0.58 7.9 3.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Adaptin_N PF01602.15 GAP90814.1 - 2.1e-142 475.1 2.5 2.4e-142 474.9 1.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 GAP90814.1 - 9.3e-21 74.2 0.0 2.2e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 GAP90814.1 - 1.9e-07 31.2 0.2 0.086 13.1 0.0 4.4 3 2 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 GAP90814.1 - 7.1e-05 23.1 0.6 8.5 7.0 0.0 5.1 4 0 0 4 4 4 1 HEAT-like repeat HEAT PF02985.17 GAP90814.1 - 0.00098 19.0 0.9 8 6.8 0.0 5.1 5 0 0 5 5 5 1 HEAT repeat RIX1 PF08167.7 GAP90814.1 - 0.0053 16.4 0.2 0.09 12.4 0.0 2.8 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis TIP120 PF08623.5 GAP90814.1 - 0.0063 16.1 2.3 0.038 13.5 0.1 2.9 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) DUF2435 PF10363.4 GAP90814.1 - 0.011 15.6 3.4 4.2 7.3 0.2 4.0 4 1 0 4 4 4 0 Protein of unknown function (DUF2435) Cnd1 PF12717.2 GAP90814.1 - 0.012 15.4 3.7 0.034 13.9 0.3 3.0 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 GAP90814.1 - 0.038 13.8 1.2 82 3.2 0.0 5.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat TonB_2 PF13103.1 GAP90814.1 - 0.13 12.3 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 TonB C terminal MAPEG PF01124.13 GAP90815.1 - 4.1e-19 68.4 3.8 5e-19 68.1 2.7 1.1 1 0 0 1 1 1 1 MAPEG family Peptidase_M14 PF00246.19 GAP90816.1 - 1.3e-61 208.6 0.0 2e-61 208.0 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Sec7 PF01369.15 GAP90817.1 - 3.5e-38 131.1 0.0 6.2e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 GAP90817.1 - 0.00093 19.3 0.0 0.0027 17.8 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 GAP90817.1 - 0.012 15.7 0.0 0.028 14.5 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain OEP PF02321.13 GAP90817.1 - 0.03 13.9 0.7 0.052 13.1 0.5 1.3 1 0 0 1 1 1 0 Outer membrane efflux protein SRP72 PF08492.7 GAP90818.1 - 3e-16 59.5 6.9 3e-16 59.5 4.8 2.1 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.1 GAP90818.1 - 1.7e-06 28.2 13.4 0.061 13.6 0.1 5.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAP90818.1 - 0.00047 20.7 5.9 0.00047 20.7 4.1 5.2 5 1 2 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAP90818.1 - 0.013 15.4 14.3 1.2 9.2 0.3 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 GAP90818.1 - 0.023 14.3 7.2 3 7.5 0.1 4.6 4 1 1 5 5 5 0 TPR repeat TPR_12 PF13424.1 GAP90818.1 - 0.11 12.3 18.2 2 8.4 2.0 5.2 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAP90818.1 - 0.12 13.0 25.8 5.8 7.8 0.1 8.1 3 2 4 8 8 8 0 Tetratricopeptide repeat TPR_9 PF13371.1 GAP90818.1 - 0.4 10.5 6.5 11 6.0 0.5 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 GAP90818.1 - 2.7 8.6 16.0 3.6 8.2 0.5 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Tropomyosin_1 PF12718.2 GAP90819.1 - 0.00012 22.0 6.6 0.084 12.7 0.1 2.7 1 1 1 2 2 2 2 Tropomyosin like Tropomyosin PF00261.15 GAP90819.1 - 0.0076 15.3 7.8 0.27 10.2 5.2 2.1 1 1 0 1 1 1 1 Tropomyosin Filament PF00038.16 GAP90819.1 - 0.071 12.5 4.4 0.048 13.1 0.4 2.0 1 1 0 2 2 2 0 Intermediate filament protein SlyX PF04102.7 GAP90819.1 - 0.079 13.3 4.3 0.32 11.3 0.1 2.9 2 1 1 3 3 3 0 SlyX Pox_A_type_inc PF04508.7 GAP90819.1 - 0.57 10.1 4.5 0.37 10.7 0.8 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat CorA PF01544.13 GAP90819.1 - 0.77 8.7 5.9 1.9 7.4 4.1 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein IncA PF04156.9 GAP90819.1 - 1.1 8.7 7.0 18 4.8 4.9 2.1 1 1 0 1 1 1 0 IncA protein PspB PF06667.7 GAP90819.1 - 2.9 7.8 5.5 27 4.7 0.1 2.8 2 1 0 2 2 2 0 Phage shock protein B DUF2414 PF10309.4 GAP90820.1 - 2.5e-17 62.3 0.0 4.4e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) HAUS6_N PF14661.1 GAP90821.1 - 0.052 12.9 0.2 0.092 12.0 0.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF2642 PF10842.3 GAP90821.1 - 0.072 12.5 0.0 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2642) DUF4135 PF13575.1 GAP90821.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Myb_DNA-binding PF00249.26 GAP90824.1 - 1.6e-23 82.5 1.3 4.6e-11 42.6 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAP90824.1 - 8.3e-18 64.2 4.2 1.5e-12 47.4 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain HTH_23 PF13384.1 GAP90824.1 - 0.081 12.6 0.2 0.2 11.3 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain Glyco_transf_41 PF13844.1 GAP90825.1 - 4.2e-94 315.1 0.1 1.3e-48 165.1 0.0 3.3 2 1 1 3 3 3 2 Glycosyl transferase family 41 TPR_11 PF13414.1 GAP90825.1 - 2e-23 81.7 5.2 2.5e-09 36.6 0.0 4.7 4 0 0 4 4 4 4 TPR repeat TPR_1 PF00515.23 GAP90825.1 - 4.1e-20 70.4 4.1 0.0011 18.4 0.0 5.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 GAP90825.1 - 9.4e-17 59.5 4.5 0.0018 18.0 0.1 6.1 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_12 PF13424.1 GAP90825.1 - 2.6e-13 49.7 3.8 2.9e-05 23.8 0.1 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAP90825.1 - 1.2e-11 43.4 0.0 0.14 12.0 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAP90825.1 - 1.4e-10 40.8 2.6 0.27 11.9 0.2 5.8 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 GAP90825.1 - 1.4e-09 37.3 0.6 0.099 12.8 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAP90825.1 - 2e-08 34.6 3.6 0.29 11.8 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 GAP90825.1 - 2.6e-07 30.3 9.1 0.65 10.0 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAP90825.1 - 4.5e-05 22.9 1.8 1.8 8.5 0.0 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat Apc3 PF12895.2 GAP90825.1 - 6.9e-05 22.9 0.8 0.028 14.5 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 GAP90825.1 - 0.00039 20.6 2.4 0.36 11.1 0.0 3.7 3 2 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAP90825.1 - 0.12 12.9 2.9 2e+02 2.7 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Coatomer_E PF04733.9 GAP90825.1 - 0.5 9.5 0.0 1.1 8.4 0.0 1.5 1 0 0 1 1 1 0 Coatomer epsilon subunit Ribosomal_L11_N PF03946.9 GAP90826.1 - 4e-18 64.6 0.1 6.3e-18 63.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 GAP90826.1 - 1.2e-09 38.1 0.1 2e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Sec23_trunk PF04811.10 GAP90827.1 - 5.2e-81 271.5 0.0 7.5e-81 271.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 GAP90827.1 - 5.1e-35 119.0 0.4 3.8e-34 116.2 0.1 2.3 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 GAP90827.1 - 3.5e-30 104.3 0.4 6.9e-30 103.4 0.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 GAP90827.1 - 3.1e-16 58.6 6.5 6.4e-16 57.6 4.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 GAP90827.1 - 6e-13 48.2 0.0 1.5e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat TMF_DNA_bd PF12329.3 GAP90829.1 - 0.00011 21.9 25.6 0.02 14.6 0.2 5.5 4 1 1 5 5 5 4 TATA element modulatory factor 1 DNA binding DUF641 PF04859.7 GAP90829.1 - 0.081 12.6 19.5 0.052 13.3 3.0 3.7 4 1 0 4 4 4 0 Plant protein of unknown function (DUF641) Phage_GP20 PF06810.6 GAP90829.1 - 4.3 6.7 17.4 0.45 9.9 3.4 3.9 3 1 1 4 4 4 0 Phage minor structural protein GP20 FlxA PF14282.1 GAP90829.1 - 8.3 6.4 16.7 0.33 10.9 4.9 3.4 3 1 0 3 3 3 0 FlxA-like protein DUF605 PF04652.11 GAP90830.1 - 0.049 13.0 3.1 0.045 13.1 2.2 1.1 1 0 0 1 1 1 0 Vta1 like API5 PF05918.6 GAP90830.1 - 0.18 10.2 2.1 0.22 9.9 1.5 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) LrgB PF04172.11 GAP90831.1 - 3.4e-19 68.8 3.5 3.4e-19 68.8 2.4 3.8 3 1 0 3 3 3 2 LrgB-like family ADP_ribosyl_GH PF03747.9 GAP90831.1 - 0.0066 16.2 1.3 0.047 13.4 1.0 2.1 2 0 0 2 2 2 1 ADP-ribosylglycohydrolase CPSF100_C PF13299.1 GAP90832.1 - 2.9e-44 151.0 0.1 7e-44 149.8 0.0 1.7 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 GAP90832.1 - 2e-27 95.5 0.0 1.3e-26 93.0 0.0 2.2 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.7 GAP90832.1 - 4.6e-05 23.1 0.1 9.1e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Sec23_trunk PF04811.10 GAP90833.1 - 2.7e-50 171.0 0.0 5.7e-50 169.9 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 GAP90833.1 - 1.9e-24 85.0 0.0 3.5e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 GAP90833.1 - 6.6e-18 65.0 0.0 1.2e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 GAP90833.1 - 6e-17 60.9 5.1 1.4e-16 59.7 3.5 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 GAP90833.1 - 2.7e-05 23.7 0.0 5.9e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat DUF2263 PF10021.4 GAP90834.1 - 1e-13 51.5 0.0 2.5e-13 50.2 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2263) SR-25 PF10500.4 GAP90834.1 - 0.57 9.6 12.1 0.83 9.0 8.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 GAP90834.1 - 6.3 6.8 15.5 10 6.1 10.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) tRNA-synt_2 PF00152.15 GAP90835.1 - 1.6e-71 240.8 0.0 1.9e-71 240.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Gti1_Pac2 PF09729.4 GAP90836.1 - 4.7e-48 163.2 9.8 8.4e-48 162.4 2.6 2.6 2 1 0 2 2 2 1 Gti1/Pac2 family HlyIII PF03006.15 GAP90837.1 - 3.6e-51 173.6 20.4 4.4e-51 173.4 14.2 1.0 1 0 0 1 1 1 1 Haemolysin-III related Linker_histone PF00538.14 GAP90838.1 - 2.8e-24 85.0 0.3 2.8e-24 85.0 0.2 2.0 2 1 1 3 3 3 1 linker histone H1 and H5 family zf-trcl PF13451.1 GAP90840.1 - 0.0093 15.5 2.5 0.081 12.5 0.5 2.3 2 0 0 2 2 2 2 Probable zinc-binding domain HET PF06985.6 GAP90842.1 - 6.1e-15 55.6 0.0 1.7e-14 54.1 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Nucleoplasmin PF03066.10 GAP90842.1 - 0.0078 15.7 4.3 0.12 11.8 0.2 2.2 2 0 0 2 2 2 2 Nucleoplasmin CENP-B_dimeris PF09026.5 GAP90842.1 - 0.046 13.9 12.1 0.74 10.0 2.2 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain BMF PF15185.1 GAP90842.1 - 0.05 12.8 1.1 0.16 11.2 0.7 1.8 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis DUF3439 PF11921.3 GAP90842.1 - 0.55 9.9 13.1 0.21 11.3 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Sigma70_ner PF04546.8 GAP90842.1 - 1 8.9 7.1 0.67 9.5 0.2 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region Myc_N PF01056.13 GAP90842.1 - 1.4 7.9 5.7 1.8 7.6 0.5 2.4 2 0 0 2 2 2 0 Myc amino-terminal region PBP1_TM PF14812.1 GAP90842.1 - 4.2 7.7 12.5 0.84 9.9 2.9 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HJURP_mid PF12346.3 GAP90843.1 - 0.042 13.9 0.3 0.067 13.3 0.2 1.3 1 0 0 1 1 1 0 Holliday junction recognition protein-associated repeat AAA_34 PF13872.1 GAP90843.1 - 0.1 11.3 1.4 0.16 10.7 0.9 1.3 1 1 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 MutS_V PF00488.16 GAP90844.1 - 3.7e-97 324.3 0.0 5.3e-97 323.8 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 GAP90844.1 - 7.8e-39 133.5 1.9 9.7e-39 133.2 0.5 1.9 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 GAP90844.1 - 7.9e-23 81.0 2.3 3.3e-22 79.0 0.0 3.0 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.15 GAP90844.1 - 5e-19 68.3 0.0 2.2e-18 66.3 0.0 2.1 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 GAP90844.1 - 1.7e-16 60.1 3.6 4e-16 58.9 1.1 2.6 2 0 0 2 2 2 1 MutS family domain IV Peptidase_M16 PF00675.15 GAP90844.1 - 0.031 14.0 0.2 0.14 11.8 0.1 2.2 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) AAA_22 PF13401.1 GAP90844.1 - 0.037 14.1 0.1 0.65 10.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain tRNA_m1G_MT PF01746.16 GAP90845.1 - 5e-32 110.9 0.0 2.7e-22 79.2 0.0 2.3 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase Fungal_trans_2 PF11951.3 GAP90846.1 - 3.1e-12 45.8 2.5 1.8e-11 43.2 1.8 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain SPC12 PF06645.8 GAP90846.1 - 0.027 14.2 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DivIC PF04977.10 GAP90846.1 - 0.41 10.1 6.0 0.5 9.8 3.0 1.8 2 0 0 2 2 2 0 Septum formation initiator Fungal_trans_2 PF11951.3 GAP90847.1 - 4.3e-12 45.3 0.0 6.3e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP90847.1 - 4.5e-07 29.6 8.9 8.1e-07 28.8 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 GAP90848.1 - 8.1e-35 120.1 59.0 1.7e-34 119.1 39.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily AflR PF08493.5 GAP90848.1 - 1.8 7.4 4.8 2.9 6.8 3.3 1.2 1 0 0 1 1 1 0 Aflatoxin regulatory protein Cellulase PF00150.13 GAP90850.1 - 4.5e-19 68.7 0.7 1.5e-18 67.0 0.5 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Myc_N PF01056.13 GAP90851.1 - 0.0079 15.3 1.7 0.0082 15.3 1.2 1.2 1 0 0 1 1 1 1 Myc amino-terminal region FAM176 PF14851.1 GAP90851.1 - 0.11 12.1 0.9 0.12 12.1 0.6 1.1 1 0 0 1 1 1 0 FAM176 family Oxysterol_BP PF01237.13 GAP90852.1 - 1.2e-51 175.3 0.0 3.1e-41 141.0 0.0 2.1 2 0 0 2 2 2 2 Oxysterol-binding protein DUF3886 PF13025.1 GAP90852.1 - 0.048 13.6 2.3 0.8 9.7 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) Fungal_trans PF04082.13 GAP90853.1 - 2e-20 72.7 0.7 3.3e-20 72.0 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP90853.1 - 3.6e-08 33.1 9.6 6e-08 32.4 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CP2 PF04516.10 GAP90855.1 - 1.8e-83 279.2 0.0 2.7e-83 278.6 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Tektin PF03148.9 GAP90855.1 - 0.06 11.8 0.0 0.094 11.2 0.0 1.2 1 0 0 1 1 1 0 Tektin family CG-1 PF03859.11 GAP90855.1 - 0.063 12.8 0.1 1.5 8.3 0.1 2.3 2 0 0 2 2 2 0 CG-1 domain PAF-AH_p_II PF03403.8 GAP90858.1 - 4.2e-15 54.9 0.1 1.5e-06 26.7 0.0 2.8 3 1 0 3 3 3 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 GAP90858.1 - 1.8e-12 47.2 0.7 3e-12 46.4 0.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP90858.1 - 1.4e-05 25.0 12.2 2.7e-05 24.1 8.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 GAP90858.1 - 0.005 15.7 0.2 0.49 9.2 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase enzyme Chlorophyllase PF07224.6 GAP90858.1 - 0.12 11.1 0.2 1.6 7.4 0.0 2.0 2 0 0 2 2 2 0 Chlorophyllase Peptidase_S9 PF00326.16 GAP90858.1 - 0.13 11.4 0.3 0.25 10.5 0.2 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family MFS_1 PF07690.11 GAP90861.1 - 2.6e-37 128.3 43.3 4.6e-37 127.5 23.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FixP_N PF14715.1 GAP90861.1 - 4.1 6.8 9.5 5.6 6.4 2.7 2.9 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Sulfate_transp PF00916.15 GAP90862.1 - 2.4e-74 249.8 9.0 2.4e-74 249.8 6.3 2.0 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 GAP90862.1 - 2.2e-30 104.1 2.8 2.2e-30 104.1 1.9 3.4 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 GAP90862.1 - 5.8e-06 25.7 0.0 1.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 STAS domain zf-C2H2 PF00096.21 GAP90863.1 - 1.1e-07 31.8 21.6 0.0023 18.1 4.4 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAP90863.1 - 1.2e-07 31.6 13.5 0.00038 20.5 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAP90863.1 - 0.00068 19.7 17.6 0.33 11.3 0.1 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger Bunya_G2 PF03563.8 GAP90863.1 - 0.68 8.7 3.1 1.1 8.1 2.2 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 zf-LYAR PF08790.6 GAP90863.1 - 3.2 7.5 6.4 0.58 9.9 0.1 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-met PF12874.2 GAP90863.1 - 6.8 7.0 7.6 30 5.0 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Rhodanese PF00581.15 GAP90864.1 - 3.5e-10 40.2 0.0 4.9e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Glyco_trans_4_4 PF13579.1 GAP90864.1 - 0.11 12.6 0.1 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Myc_N PF01056.13 GAP90865.1 - 0.073 12.2 1.0 0.12 11.5 0.7 1.4 1 0 0 1 1 1 0 Myc amino-terminal region GSK-3_bind PF05350.7 GAP90865.1 - 0.32 10.4 5.3 0.083 12.3 0.8 2.0 2 0 0 2 2 2 0 Glycogen synthase kinase-3 binding Arginase PF00491.16 GAP90866.1 - 2.6e-77 259.8 0.1 3.1e-77 259.6 0.1 1.0 1 0 0 1 1 1 1 Arginase family MARVEL PF01284.18 GAP90867.1 - 1.9e-05 24.5 14.4 2.8e-05 23.9 10.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF3733 PF12534.3 GAP90867.1 - 6 6.2 6.5 2 7.7 1.5 2.3 1 1 2 3 3 3 0 Leucine-rich repeat containing protein 8 Virul_fac_BrkB PF03631.10 GAP90867.1 - 8.6 5.6 20.5 0.18 11.1 9.1 1.7 2 0 0 2 2 2 0 Virulence factor BrkB Glyco_transf_90 PF05686.7 GAP90868.1 - 1.2e-13 50.5 0.2 2.5e-10 39.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 90 RrnaAD PF00398.15 GAP90869.1 - 1.1e-06 27.9 0.0 3.3e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Ank_2 PF12796.2 GAP90871.1 - 1.2e-22 79.9 5.1 1.7e-11 44.3 1.5 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAP90871.1 - 3.7e-18 64.3 14.1 9.4e-08 31.4 0.3 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 GAP90871.1 - 3.8e-16 58.7 9.5 8.5e-06 25.8 0.2 5.2 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP90871.1 - 1.2e-15 56.0 6.5 0.00014 21.7 0.1 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 GAP90871.1 - 1.7e-13 50.6 6.3 3.6e-07 30.4 0.2 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) PNPase_C PF12111.3 GAP90871.1 - 0.34 10.1 6.8 1.1 8.5 4.7 1.8 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal SLBB PF10531.4 GAP90872.1 - 0.015 15.1 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 SLBB domain DUF1993 PF09351.5 GAP90873.1 - 9e-45 152.4 0.0 1e-44 152.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DeoC PF01791.4 GAP90874.1 - 2.3e-40 138.3 1.6 3.2e-40 137.8 1.1 1.2 1 0 0 1 1 1 1 DeoC/LacD family aldolase Fungal_trans PF04082.13 GAP90874.1 - 0.00096 18.0 0.0 0.0018 17.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain BAAT_C PF08840.6 GAP90874.1 - 0.13 11.9 0.1 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1479 PF07350.7 GAP90875.1 - 2e-160 533.8 0.0 2.3e-160 533.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 GAP90875.1 - 0.00025 21.1 0.0 0.047 13.7 0.0 2.4 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) TauD PF02668.11 GAP90875.1 - 0.0019 17.9 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 GAP90876.1 - 1.7e-36 125.6 34.2 1.7e-36 125.6 23.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 GAP90876.1 - 3.3e-05 22.2 3.7 3.8e-05 22.0 0.6 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector TRI12 PF06609.8 GAP90876.1 - 0.0001 20.6 4.7 0.00019 19.7 3.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Aldo_ket_red PF00248.16 GAP90877.1 - 9.9e-47 159.1 0.0 1.1e-46 158.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DAP3 PF10236.4 GAP90877.1 - 0.037 12.9 0.0 0.14 11.0 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Zn_clus PF00172.13 GAP90878.1 - 1.1e-08 34.8 12.8 2e-08 34.0 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2797 PF10977.3 GAP90878.1 - 0.23 11.0 2.1 0.38 10.3 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) AMP-binding PF00501.23 GAP90879.1 - 2.8e-79 266.4 0.0 4.7e-79 265.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 GAP90879.1 - 4.1e-75 252.5 0.0 6.9e-75 251.8 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAP90879.1 - 3.3e-55 187.6 0.0 7.2e-55 186.5 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 GAP90879.1 - 2.9e-54 183.4 0.8 6.8e-53 179.0 0.0 3.1 4 0 0 4 4 3 1 KR domain Condensation PF00668.15 GAP90879.1 - 7.9e-51 172.6 0.2 1.3e-50 172.0 0.2 1.3 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 GAP90879.1 - 2.3e-47 160.9 0.2 1.2e-43 148.9 0.0 3.2 3 0 0 3 3 3 2 short chain dehydrogenase PS-DH PF14765.1 GAP90879.1 - 6.1e-45 153.6 0.0 1e-44 152.9 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase NAD_binding_4 PF07993.7 GAP90879.1 - 9.7e-44 149.1 0.0 4.3e-43 147.0 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.17 GAP90879.1 - 1.1e-28 99.4 0.1 2.8e-28 98.1 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 GAP90879.1 - 1.6e-19 70.1 0.0 4.3e-19 68.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 GAP90879.1 - 2.9e-16 59.4 2.6 1.4e-09 38.1 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 GAP90879.1 - 5.2e-15 55.5 0.0 1.4e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 GAP90879.1 - 2.1e-14 53.5 0.0 2.2e-11 43.6 0.0 2.7 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.7 GAP90879.1 - 4.3e-14 52.7 0.0 1.4e-13 51.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 GAP90879.1 - 1.9e-13 49.7 0.0 1.4e-09 37.1 0.0 2.5 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_31 PF13847.1 GAP90879.1 - 3.7e-13 49.3 0.0 9.6e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 GAP90879.1 - 1.6e-12 47.5 0.0 5.6e-12 45.8 0.0 2.1 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_18 PF12847.2 GAP90879.1 - 1.6e-09 38.3 0.0 6.2e-09 36.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP90879.1 - 3.7e-07 29.5 0.0 7.9e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 GAP90879.1 - 9.9e-05 22.3 0.0 0.00032 20.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 GAP90879.1 - 0.00046 19.6 0.0 0.001 18.5 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Thiolase_N PF00108.18 GAP90879.1 - 0.00052 19.0 0.0 0.001 18.1 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_8 PF05148.10 GAP90879.1 - 0.027 14.0 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase NodS PF05401.6 GAP90879.1 - 0.033 13.5 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Semialdhyde_dh PF01118.19 GAP90879.1 - 0.055 13.7 0.0 0.37 11.1 0.0 2.5 2 0 0 2 2 1 0 Semialdehyde dehydrogenase, NAD binding domain RrnaAD PF00398.15 GAP90879.1 - 0.1 11.6 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NNMT_PNMT_TEMT PF01234.12 GAP90879.1 - 0.48 9.3 0.0 1.2 8.0 0.0 1.6 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family p450 PF00067.17 GAP90880.1 - 2.1e-35 122.1 0.0 2.9e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 GAP90881.1 - 7.5e-48 163.0 49.5 1.9e-47 161.7 34.3 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAP90881.1 - 3.5e-17 61.8 15.3 5.5e-17 61.2 10.6 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAP90881.1 - 1.3e-13 50.3 14.0 1.3e-13 50.3 9.7 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter Abhydrolase_5 PF12695.2 GAP90882.1 - 1.3e-09 38.0 0.0 3.3e-09 36.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP90882.1 - 8.2e-08 32.4 0.0 4.2e-07 30.0 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAP90882.1 - 0.0036 16.5 0.1 0.007 15.6 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family ADH_zinc_N PF00107.21 GAP90884.1 - 1.1e-08 34.7 0.0 1.9e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP90884.1 - 3.4e-07 29.9 0.4 4.4e-06 26.4 0.2 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.17 GAP90885.1 - 5.5e-40 137.2 0.0 7.4e-40 136.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_3 PF13738.1 GAP90886.1 - 2.1e-27 96.4 0.0 3.9e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP90886.1 - 9.6e-11 41.5 0.0 3.5e-08 33.3 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAP90886.1 - 4.9e-07 29.8 0.0 4.2e-05 23.5 0.0 2.7 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAP90886.1 - 7e-07 28.4 0.1 2.8e-06 26.4 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain FMO-like PF00743.14 GAP90886.1 - 3.2e-06 25.6 1.3 3.3e-05 22.3 0.2 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Shikimate_DH PF01488.15 GAP90886.1 - 3.7e-06 27.0 0.4 0.014 15.5 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 GAP90886.1 - 1.6e-05 24.0 0.5 8.3e-05 21.6 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 GAP90886.1 - 1.8e-05 23.8 0.0 0.00079 18.4 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 GAP90886.1 - 0.0002 21.1 0.8 0.23 11.2 0.0 3.6 3 1 0 4 4 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 GAP90886.1 - 0.00031 19.9 0.3 0.0058 15.7 0.2 2.6 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.17 GAP90886.1 - 0.0025 16.7 0.4 1.5 7.5 0.5 2.7 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 GAP90886.1 - 0.0044 16.1 0.2 0.0074 15.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 GAP90886.1 - 0.0054 16.9 0.0 0.38 11.0 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 GAP90886.1 - 0.0098 15.0 0.0 0.089 11.9 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 GAP90886.1 - 0.013 15.8 0.7 7.3 7.0 0.7 3.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAP90886.1 - 0.078 11.8 0.0 0.14 10.9 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Malic_M PF03949.10 GAP90886.1 - 0.1 12.1 0.1 0.89 9.0 0.0 2.1 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain ThiF PF00899.16 GAP90886.1 - 0.12 12.2 3.4 0.077 12.8 0.7 1.9 2 0 0 2 2 2 0 ThiF family FAD_oxidored PF12831.2 GAP90886.1 - 0.12 11.4 0.5 0.19 10.7 0.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 GAP90886.1 - 0.16 10.3 1.3 0.85 8.0 1.6 1.7 2 0 0 2 2 2 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 GAP90886.1 - 0.22 10.8 0.8 0.41 10.0 0.6 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Zn_clus PF00172.13 GAP90887.1 - 6.8e-05 22.6 7.2 0.00021 21.1 5.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1103 PF06513.6 GAP90888.1 - 0.031 13.6 0.1 0.049 13.0 0.1 1.2 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) Arch_ATPase PF01637.13 GAP90889.1 - 4.4e-08 33.1 0.1 8e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 GAP90889.1 - 2.9e-07 30.6 2.6 3.7e-06 27.0 1.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAP90889.1 - 0.028 14.5 0.0 0.061 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.8 GAP90889.1 - 0.037 13.5 0.1 0.068 12.6 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DUF815 PF05673.8 GAP90889.1 - 0.045 12.6 0.0 0.089 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 GAP90889.1 - 0.055 12.9 0.0 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_tran PF00005.22 GAP90889.1 - 0.1 12.9 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Miro PF08477.8 GAP90889.1 - 0.11 13.0 0.0 0.66 10.4 0.0 2.2 2 1 0 3 3 3 0 Miro-like protein AAA_29 PF13555.1 GAP90889.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain KaiC PF06745.8 GAP90889.1 - 0.15 11.1 0.5 0.48 9.4 0.4 1.8 1 1 0 1 1 1 0 KaiC DUF1295 PF06966.7 GAP90890.1 - 1.5e-30 106.2 0.0 2.2e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 GAP90890.1 - 3e-06 27.0 0.0 7.3e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 GAP90890.1 - 0.00036 20.6 0.0 0.00082 19.4 0.0 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.9 GAP90890.1 - 0.00098 19.2 0.0 0.0018 18.4 0.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.12 GAP90890.1 - 0.049 12.1 0.0 0.11 11.0 0.0 1.5 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family VID27 PF08553.5 GAP90891.1 - 0 1119.3 0.1 0 1119.0 0.1 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein F-box PF00646.28 GAP90892.1 - 0.015 14.9 0.8 0.061 13.0 0.6 2.1 2 0 0 2 2 2 0 F-box domain Rsa3 PF14615.1 GAP90892.1 - 0.025 13.8 0.0 0.062 12.5 0.0 1.6 1 0 0 1 1 1 0 Ribosome-assembly protein 3 F-box-like PF12937.2 GAP90892.1 - 0.07 12.8 2.3 0.36 10.6 1.1 2.5 2 1 0 2 2 2 0 F-box-like DUF3960 PF13142.1 GAP90892.1 - 0.086 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3960) Aegerolysin PF06355.8 GAP90893.1 - 3.7e-08 33.3 0.5 6.7e-08 32.4 0.3 1.4 1 0 0 1 1 1 1 Aegerolysin GMC_oxred_N PF00732.14 GAP90894.1 - 4.3e-78 262.4 0.0 5.9e-78 262.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAP90894.1 - 1e-36 126.3 0.0 2.2e-36 125.2 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAP90894.1 - 3e-06 26.3 0.0 0.0048 15.8 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAP90894.1 - 0.0013 17.7 0.1 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAP90894.1 - 0.002 17.0 0.1 0.86 8.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 GAP90894.1 - 0.011 14.7 0.0 0.037 13.1 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.9 GAP90894.1 - 0.053 13.3 0.0 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase tRNA-synt_1g PF09334.6 GAP90895.1 - 5.3e-132 440.1 0.1 5.8e-70 235.9 0.0 2.2 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 GAP90895.1 - 1.5e-09 36.4 1.1 0.013 13.5 0.0 4.2 5 0 0 5 5 5 3 tRNA synthetases class I (I, L, M and V) DUF3987 PF13148.1 GAP90895.1 - 0.021 13.4 4.7 0.031 12.8 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Zn_clus PF00172.13 GAP90897.1 - 7.5e-18 64.1 25.0 4.3e-09 36.1 4.7 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAP90897.1 - 2.6e-08 33.0 0.2 3.8e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_3 PF07859.8 GAP90899.1 - 2.3e-27 95.9 0.2 3.2e-27 95.5 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 GAP90899.1 - 3.1e-08 32.6 0.0 1.3e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 GAP90899.1 - 0.0044 16.7 0.5 0.0066 16.2 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 GAP90899.1 - 0.0076 15.0 0.1 0.018 13.7 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 GAP90899.1 - 0.07 12.3 0.0 2.2 7.4 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family FAD_binding_4 PF01565.18 GAP90900.1 - 1.3e-23 82.9 0.1 2.3e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP90900.1 - 1.4e-05 24.8 0.7 3.7e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Berberine and berberine like NOB1_Zn_bind PF08772.6 GAP90901.1 - 1.5e-31 107.9 2.8 2.8e-31 107.1 2.0 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 GAP90901.1 - 0.0023 17.7 15.1 0.0023 17.7 10.5 2.4 2 1 0 2 2 2 1 Drug resistance and apoptosis regulator zf-NADH-PPase PF09297.6 GAP90901.1 - 0.016 14.7 1.5 0.016 14.7 1.0 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain HypA PF01155.14 GAP90901.1 - 0.092 12.4 0.1 2.8 7.6 1.0 2.1 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 GAP90901.1 - 0.25 11.1 2.5 0.51 10.1 1.7 1.4 1 0 0 1 1 1 0 Double zinc ribbon Myc_N PF01056.13 GAP90901.1 - 0.98 8.5 10.7 1.5 7.9 7.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Sulfotransfer_3 PF13469.1 GAP90902.1 - 0.4 11.5 4.6 0.46 11.4 2.8 1.4 1 1 0 1 1 1 0 Sulfotransferase family MFS_1 PF07690.11 GAP90903.1 - 5.9e-40 137.0 37.1 5.9e-40 137.0 25.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP90903.1 - 2.8e-08 32.7 26.1 4.5e-08 32.1 18.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 GAP90903.1 - 3.9e-08 31.9 4.1 6.5e-08 31.2 2.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TGT PF01702.13 GAP90904.1 - 2.4e-32 112.1 0.0 3.2e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase LCCL PF03815.14 GAP90905.1 - 1.3e-20 73.2 0.1 2e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 LCCL domain DUF2190 PF09956.4 GAP90907.1 - 0.059 13.1 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2190) Alk_phosphatase PF00245.15 GAP90908.1 - 3.4e-65 220.3 0.0 3.1e-60 204.0 0.0 2.1 2 0 0 2 2 2 2 Alkaline phosphatase Sulfatase PF00884.18 GAP90908.1 - 1.3e-05 24.5 0.0 2.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 GAP90908.1 - 0.0002 20.8 0.2 0.00037 19.9 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 GAP90908.1 - 0.0039 15.6 0.2 0.0072 14.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF1501 PF07394.7 GAP90908.1 - 0.062 12.1 0.4 0.092 11.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Cellulase PF00150.13 GAP90909.1 - 1.4e-51 175.3 0.0 1.7e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PLDc_2 PF13091.1 GAP90910.1 - 1.9e-12 46.9 0.0 4.3e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 GAP90910.1 - 1.7e-07 30.7 3.9 0.01 15.5 0.0 3.9 4 0 0 4 4 4 3 Phospholipase D Active site motif NDUFA12 PF05071.11 GAP90911.1 - 5.9e-26 90.9 3.0 7.9e-26 90.5 2.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 TRAP_alpha PF03896.11 GAP90912.1 - 0.00048 19.2 8.3 0.00048 19.2 5.7 1.5 2 0 0 2 2 2 1 Translocon-associated protein (TRAP), alpha subunit Nop25 PF09805.4 GAP90912.1 - 7.9 6.5 15.8 12 5.9 10.9 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Daxx PF03344.10 GAP90912.1 - 9.1 4.6 26.6 12 4.2 18.4 1.0 1 0 0 1 1 1 0 Daxx Family SpoIIIAH PF12685.2 GAP90912.1 - 10 5.5 11.2 41 3.5 7.8 1.8 1 1 0 1 1 1 0 SpoIIIAH-like protein p450 PF00067.17 GAP90913.1 - 9.5e-53 179.3 0.0 1.3e-52 178.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 GAP90915.1 - 9.5e-27 93.7 0.0 2.2e-26 92.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP90915.1 - 2e-13 50.0 0.2 1.3e-05 24.4 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Grp1_Fun34_YaaH PF01184.14 GAP90917.1 - 2.9e-28 98.6 15.3 3.8e-28 98.2 10.6 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Gram_pos_anchor PF00746.16 GAP90917.1 - 2 8.3 8.9 0.27 11.0 1.3 2.5 2 0 0 2 2 2 0 Gram positive anchor UPF0220 PF05255.6 GAP90917.1 - 2.3 7.4 8.3 0.42 9.8 2.1 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0220) adh_short PF00106.20 GAP90918.1 - 1.1e-28 100.2 5.4 1.4e-28 99.9 3.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP90918.1 - 2.2e-27 96.3 0.6 2.7e-27 96.1 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP90918.1 - 7e-16 58.4 2.5 9.4e-16 57.9 1.7 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAP90918.1 - 1.1e-05 24.9 2.3 1.4e-05 24.6 1.1 1.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAP90918.1 - 6.5e-05 23.0 2.2 0.00014 21.9 1.5 1.5 1 1 0 1 1 1 1 NADH(P)-binding Glyco_trans_4_4 PF13579.1 GAP90918.1 - 0.021 14.9 0.1 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain 3Beta_HSD PF01073.14 GAP90918.1 - 0.044 12.4 0.6 0.056 12.1 0.4 1.3 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AIRC PF00731.15 GAP90918.1 - 0.083 12.1 0.7 0.44 9.8 0.0 2.1 2 0 0 2 2 2 0 AIR carboxylase DUF2493 PF10686.4 GAP90918.1 - 0.14 11.6 0.8 0.4 10.2 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2493) FAD_binding_3 PF01494.14 GAP90919.1 - 9.6e-22 77.5 0.0 1.2e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAP90919.1 - 8e-15 54.5 1.1 3e-07 29.6 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAP90919.1 - 4.4e-05 22.4 0.8 8e-05 21.6 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 GAP90919.1 - 0.00011 22.2 0.0 0.00031 20.6 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP90919.1 - 0.00011 22.1 0.4 0.00026 20.9 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAP90919.1 - 0.00015 20.4 0.9 0.0039 15.7 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 GAP90919.1 - 0.00031 19.9 0.3 0.0005 19.2 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 GAP90919.1 - 0.00057 20.2 0.3 0.99 9.8 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 GAP90919.1 - 0.00064 18.6 0.0 0.0032 16.3 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.7 GAP90919.1 - 0.00089 18.2 0.1 0.0025 16.7 0.1 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 GAP90919.1 - 0.002 18.2 0.0 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAP90919.1 - 0.0033 16.5 0.4 0.0044 16.1 0.3 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 GAP90919.1 - 0.0042 16.0 0.1 0.0066 15.3 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 GAP90919.1 - 0.06 11.9 0.3 0.77 8.3 0.1 2.1 1 1 1 2 2 2 0 Tryptophan halogenase Amino_oxidase PF01593.19 GAP90919.1 - 0.069 12.2 0.8 0.14 11.1 0.0 1.9 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 GAP90919.1 - 0.18 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cep57_CLD_2 PF14197.1 GAP90920.1 - 0.00038 20.3 2.9 0.0012 18.7 2.0 1.8 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 HALZ PF02183.13 GAP90920.1 - 0.0037 16.9 1.8 0.0089 15.7 1.2 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper DivIC PF04977.10 GAP90920.1 - 0.017 14.6 0.7 0.04 13.4 0.5 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF1875 PF08961.5 GAP90920.1 - 0.02 14.2 0.2 0.039 13.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) DUF972 PF06156.8 GAP90920.1 - 0.022 15.0 0.1 0.047 14.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4201 PF13870.1 GAP90920.1 - 0.038 13.4 0.7 0.069 12.5 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF904 PF06005.7 GAP90920.1 - 0.041 14.1 0.0 0.077 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Rab5-bind PF09311.6 GAP90920.1 - 0.051 13.4 0.5 0.12 12.2 0.3 1.6 1 0 0 1 1 1 0 Rabaptin-like protein Atg14 PF10186.4 GAP90920.1 - 0.17 10.8 0.5 0.33 9.8 0.4 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF904 PF06005.7 GAP90922.1 - 0.04 14.2 0.3 0.098 12.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF4539 PF15072.1 GAP90922.1 - 0.077 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) Cep57_CLD_2 PF14197.1 GAP90922.1 - 0.094 12.6 3.1 0.086 12.7 0.5 2.1 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 NYD-SP28_assoc PF14775.1 GAP90922.1 - 0.12 12.1 1.6 0.29 10.8 1.1 1.6 1 0 0 1 1 1 0 Sperm tail C-terminal domain Herpes_UL6 PF01763.11 GAP90922.1 - 0.19 9.8 1.1 0.26 9.4 0.4 1.4 2 0 0 2 2 2 0 Herpesvirus UL6 like bZIP_2 PF07716.10 GAP90922.1 - 0.3 10.9 4.1 0.54 10.1 0.8 2.4 2 0 0 2 2 2 0 Basic region leucine zipper IncA PF04156.9 GAP90922.1 - 0.37 10.3 2.1 0.81 9.2 1.4 1.5 1 0 0 1 1 1 0 IncA protein bZIP_1 PF00170.16 GAP90922.1 - 0.66 9.9 4.7 0.14 12.1 0.6 1.9 2 0 0 2 2 2 0 bZIP transcription factor DUF972 PF06156.8 GAP90922.1 - 1.2 9.4 4.4 1.2 9.4 0.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF1688 PF07958.6 GAP90924.1 - 2.7e-173 576.3 0.0 3.2e-173 576.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) 60KD_IMP PF02096.15 GAP90925.1 - 3.5e-25 88.8 1.1 6.3e-25 88.0 0.7 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein TOM13 PF08219.6 GAP90926.1 - 3.9e-30 103.4 0.0 4.9e-30 103.1 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 SEP PF08059.8 GAP90927.1 - 8e-25 86.9 0.0 1.8e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.1 GAP90927.1 - 3e-11 42.6 2.7 5.3e-11 41.8 1.9 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 GAP90927.1 - 2.6e-10 40.2 0.0 4.6e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 UBX domain Cwf_Cwc_15 PF04889.7 GAP90927.1 - 0.12 12.1 1.0 0.19 11.4 0.7 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1524 PF07510.6 GAP90928.1 - 6.3e-13 48.7 0.0 8.3e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) Gtr1_RagA PF04670.7 GAP90929.1 - 6e-94 313.5 0.2 8.2e-94 313.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 GAP90929.1 - 1e-08 34.7 0.1 1.8e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.16 GAP90929.1 - 3.8e-08 32.7 0.2 6e-08 32.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAP90929.1 - 1.3e-05 25.0 0.0 2.6e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAP90929.1 - 5.5e-05 23.6 0.0 0.00016 22.1 0.0 1.8 2 0 0 2 2 1 1 Miro-like protein AAA_29 PF13555.1 GAP90929.1 - 0.00065 19.1 0.7 0.0066 15.9 0.2 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.8 GAP90929.1 - 0.0021 17.0 0.1 0.0051 15.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 GAP90929.1 - 0.0025 18.1 0.2 0.005 17.1 0.2 1.9 1 1 0 1 1 1 1 ABC transporter G-alpha PF00503.15 GAP90929.1 - 0.0072 15.0 1.0 0.16 10.6 0.2 2.2 2 0 0 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.22 GAP90929.1 - 0.027 13.9 0.2 0.051 13.0 0.1 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF258 PF03193.11 GAP90929.1 - 0.035 13.2 0.0 0.063 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DAP3 PF10236.4 GAP90929.1 - 0.077 11.9 1.5 0.27 10.1 0.8 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Peptidase_M9_N PF08453.5 GAP90929.1 - 0.084 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M9 N-terminal Sigma54_activat PF00158.21 GAP90929.1 - 0.09 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Tox-ART-HYD1 PF15633.1 GAP90930.1 - 0.013 16.2 0.3 6.5 7.6 0.0 2.3 1 1 1 2 2 2 0 HYD1 signature containing ADP-ribosyltransferase Lipase_GDSL_2 PF13472.1 GAP90931.1 - 1.5e-13 51.3 4.0 1.8e-13 50.9 2.7 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAP90931.1 - 1.1e-10 41.7 0.4 1.4e-10 41.3 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Opi1 PF08618.5 GAP90932.1 - 5.3e-77 259.5 0.0 2.1e-56 191.6 1.5 4.0 2 1 1 3 3 3 2 Transcription factor Opi1 Perilipin PF03036.11 GAP90932.1 - 0.26 10.0 1.5 0.4 9.4 0.1 1.8 2 0 0 2 2 2 0 Perilipin family Adap_comp_sub PF00928.16 GAP90933.1 - 5.2e-91 304.3 0.0 7e-91 303.9 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 GAP90933.1 - 5.8e-09 35.8 0.2 9.4e-09 35.1 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 GAP90933.1 - 0.13 11.4 0.0 0.71 9.0 0.0 1.9 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain RecU PF03838.9 GAP90933.1 - 0.13 11.7 0.4 7 6.1 0.1 2.3 2 0 0 2 2 2 0 Recombination protein U HET PF06985.6 GAP90934.1 - 1.1e-19 70.9 2.8 1.8e-15 57.3 0.1 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.13 GAP90935.1 - 6.1e-45 153.1 0.0 9.5e-45 152.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 GAP90935.1 - 9e-10 38.3 9.6 0.00019 21.5 1.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP90935.1 - 2.8e-06 27.2 8.8 0.0017 18.5 1.6 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger Rop PF01815.11 GAP90935.1 - 0.0014 18.0 0.5 0.0045 16.4 0.3 1.8 1 0 0 1 1 1 1 Rop protein zf-C2H2_6 PF13912.1 GAP90935.1 - 0.84 9.6 6.7 0.12 12.2 0.2 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAP90935.1 - 1.1 9.6 12.7 0.063 13.5 0.6 3.6 3 0 0 3 3 3 0 Zinc-finger double domain Lactamase_B PF00753.22 GAP90936.1 - 6.7e-06 25.8 4.0 2.2e-05 24.1 2.8 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAP90936.1 - 8.5e-05 22.1 0.1 0.00014 21.5 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain CMD PF02627.15 GAP90937.1 - 1.5e-07 31.1 0.1 3.3e-07 30.0 0.0 1.6 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family MFS_1 PF07690.11 GAP90938.1 - 2.1e-37 128.6 26.3 2.9e-37 128.2 18.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2109 PF09882.4 GAP90938.1 - 0.033 14.1 0.8 0.094 12.6 0.3 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) CMD PF02627.15 GAP90939.1 - 2.7e-20 71.9 0.1 5.6e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family ADH_zinc_N PF00107.21 GAP90940.1 - 2.6e-08 33.4 0.1 4.8e-08 32.6 0.1 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP90940.1 - 1.2e-05 25.0 0.0 2.1e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Lactamase_B PF00753.22 GAP90941.1 - 6.1e-05 22.7 3.9 0.00091 18.9 2.7 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAP90941.1 - 0.00089 18.8 0.1 0.0014 18.2 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF3246 PF11596.3 GAP90941.1 - 0.36 10.0 5.0 0.56 9.4 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) NAD_binding_11 PF14833.1 GAP90942.1 - 3e-24 85.3 0.1 5e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 GAP90942.1 - 1.4e-12 47.7 0.1 2.7e-12 46.8 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase MFS_1 PF07690.11 GAP90943.1 - 2.7e-30 105.2 31.7 2.7e-30 105.2 21.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP90943.1 - 3.8e-11 42.2 9.8 3.8e-11 42.2 6.8 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter ATG22 PF11700.3 GAP90943.1 - 8.2e-08 31.1 9.5 8.2e-08 31.1 6.6 2.5 1 1 1 2 2 2 1 Vacuole effluxer Atg22 like Folate_carrier PF01770.13 GAP90943.1 - 0.057 11.9 1.2 0.093 11.2 0.8 1.3 1 0 0 1 1 1 0 Reduced folate carrier tRNA_int_endo PF01974.12 GAP90944.1 - 1.3e-18 66.5 0.0 2.4e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 GAP90944.1 - 8.8e-09 34.7 0.0 1.7e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Glyco_tranf_2_3 PF13641.1 GAP90945.1 - 4.6e-13 49.4 0.2 2.4e-12 47.1 0.1 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 GAP90945.1 - 3.1e-10 39.5 0.1 0.00042 19.6 0.0 3.4 2 1 1 3 3 3 3 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 GAP90945.1 - 0.0002 21.1 0.1 0.049 13.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 2 RasGAP PF00616.14 GAP90946.1 - 0.069 12.7 0.0 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase DUF4479 PF14794.1 GAP90946.1 - 0.28 10.7 0.0 0.62 9.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4479) tRNA-synt_1c PF00749.16 GAP90947.1 - 9e-100 333.3 0.0 1.2e-99 332.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 GAP90947.1 - 1.3e-39 135.6 0.1 3.4e-39 134.2 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 GAP90947.1 - 0.00058 20.3 0.0 0.0036 17.7 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 GAP90947.1 - 0.014 14.4 0.2 0.038 13.1 0.1 1.6 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain PPR_1 PF12854.2 GAP90947.1 - 0.12 11.8 0.1 0.38 10.2 0.1 1.9 1 0 0 1 1 1 0 PPR repeat Ribosomal_L1 PF00687.16 GAP90948.1 - 1.1e-21 77.1 0.0 2e-21 76.3 0.0 1.4 1 1 1 2 2 2 1 Ribosomal protein L1p/L10e family DUF2688 PF10892.3 GAP90948.1 - 0.048 13.3 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) COG2 PF06148.6 GAP90949.1 - 3.2e-24 85.3 0.0 4.7e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 GAP90949.1 - 0.0018 18.0 0.0 0.0068 16.2 0.0 2.0 3 0 0 3 3 3 1 Vps51/Vps67 GLTSCR1 PF15249.1 GAP90949.1 - 0.13 12.4 0.0 0.33 11.0 0.0 1.7 2 0 0 2 2 2 0 Glioma tumor suppressor candidate region Hap4_Hap_bind PF10297.4 GAP90950.1 - 5.9e-09 35.4 7.1 5.9e-09 35.4 4.9 2.5 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 GAP90950.1 - 4.2e-05 23.4 18.2 0.00068 19.5 7.4 3.0 1 1 2 3 3 3 1 bZIP transcription factor TMPIT PF07851.8 GAP90950.1 - 0.004 16.2 2.3 0.0058 15.7 1.6 1.1 1 0 0 1 1 1 1 TMPIT-like protein zf-C4H2 PF10146.4 GAP90950.1 - 0.0041 17.1 4.8 0.0041 17.1 3.3 2.5 2 2 1 3 3 2 1 Zinc finger-containing protein SPX PF03105.14 GAP90950.1 - 0.021 14.6 0.2 0.027 14.2 0.2 1.3 1 0 0 1 1 1 0 SPX domain DUF972 PF06156.8 GAP90950.1 - 0.029 14.7 3.3 0.086 13.1 2.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF972) IncA PF04156.9 GAP90950.1 - 0.031 13.8 9.8 0.062 12.8 6.8 1.4 1 0 0 1 1 1 0 IncA protein Glutaredoxin2_C PF04399.8 GAP90950.1 - 0.047 13.2 1.7 0.11 12.0 1.2 1.6 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain AAA_13 PF13166.1 GAP90950.1 - 0.052 12.0 3.0 0.078 11.4 2.1 1.2 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.7 GAP90950.1 - 0.068 12.9 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF848 PF05852.6 GAP90950.1 - 0.082 12.7 5.7 0.18 11.6 3.9 1.6 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) HAP1_N PF04849.8 GAP90950.1 - 0.082 11.8 8.6 0.13 11.2 5.9 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region CENP-F_leu_zip PF10473.4 GAP90950.1 - 0.11 12.3 11.8 0.03 14.1 6.1 1.5 2 0 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TBPIP PF07106.8 GAP90950.1 - 0.12 11.9 4.1 0.21 11.1 2.9 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Atg14 PF10186.4 GAP90950.1 - 0.18 10.6 6.6 0.31 9.9 4.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1664 PF07889.7 GAP90950.1 - 0.27 11.0 1.2 0.5 10.1 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) GAS PF13851.1 GAP90950.1 - 0.3 10.2 10.5 0.49 9.5 7.3 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding HAUS6_N PF14661.1 GAP90950.1 - 0.37 10.0 5.6 0.73 9.1 3.9 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Prominin PF05478.6 GAP90950.1 - 0.71 7.3 2.0 0.99 6.8 1.4 1.1 1 0 0 1 1 1 0 Prominin APG6 PF04111.7 GAP90950.1 - 0.86 8.5 7.8 1.6 7.6 5.4 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 GAP90950.1 - 0.86 7.3 3.2 1.3 6.8 2.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YlqD PF11068.3 GAP90950.1 - 0.95 9.5 6.9 0.84 9.6 3.4 1.7 1 1 0 1 1 1 0 YlqD protein DUF4407 PF14362.1 GAP90950.1 - 1 8.2 4.4 1.8 7.4 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.10 GAP90950.1 - 1.5 8.3 5.4 5 6.6 3.5 2.1 1 1 0 1 1 1 0 Septum formation initiator ADIP PF11559.3 GAP90950.1 - 1.6 8.6 15.7 1.2 9.0 8.8 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF342 PF03961.8 GAP90950.1 - 1.7 6.9 4.1 2.6 6.3 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) bZIP_Maf PF03131.12 GAP90950.1 - 3.3 8.0 15.9 0.76 10.1 6.3 2.4 1 1 1 2 2 2 0 bZIP Maf transcription factor Kinetocho_Slk19 PF12709.2 GAP90950.1 - 4.4 7.4 8.3 3.3 7.8 2.4 2.3 1 1 1 2 2 2 0 Central kinetochore-associated Mnd1 PF03962.10 GAP90950.1 - 4.4 6.9 7.9 9.4 5.8 5.5 1.5 1 0 0 1 1 1 0 Mnd1 family bZIP_2 PF07716.10 GAP90950.1 - 5 7.0 19.7 1 9.2 9.9 2.3 1 1 1 2 2 2 0 Basic region leucine zipper Acetyltransf_1 PF00583.19 GAP90951.1 - 3.3e-05 23.8 0.2 0.00025 21.0 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAP90951.1 - 0.00021 21.3 0.0 0.00042 20.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAP90951.1 - 0.0057 16.5 0.0 0.28 11.0 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Bac_DNA_binding PF00216.16 GAP90951.1 - 0.03 14.3 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial DNA-binding protein Acetyltransf_10 PF13673.1 GAP90951.1 - 0.076 13.1 0.0 0.3 11.2 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAP90951.1 - 0.098 12.4 0.1 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 FR47-like protein AA_permease_2 PF13520.1 GAP90952.1 - 2.2e-38 131.9 51.9 2.9e-38 131.5 35.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAP90952.1 - 4e-23 81.5 48.3 4.9e-23 81.2 33.5 1.0 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_61 PF03443.9 GAP90953.1 - 1.1e-58 198.6 0.0 1.8e-58 197.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 GAP90953.1 - 2.1e-12 46.4 8.4 2.1e-12 46.4 5.8 3.4 4 1 0 4 4 4 1 Fungal cellulose binding domain NPCBM_assoc PF10633.4 GAP90953.1 - 0.028 14.4 2.4 0.3 11.1 0.0 3.1 4 0 0 4 4 4 0 NPCBM-associated, NEW3 domain of alpha-galactosidase MFS_1 PF07690.11 GAP90954.1 - 7.4e-47 159.7 53.4 7.4e-47 159.7 37.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Iso_dh PF00180.15 GAP90957.1 - 3.9e-88 295.7 0.0 4.4e-88 295.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase 4HBT PF03061.17 GAP90958.1 - 2.9e-05 24.1 0.0 5.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily ABC_membrane PF00664.18 GAP90959.1 - 3.1e-74 249.8 42.9 3.9e-39 134.7 10.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAP90959.1 - 3.1e-67 225.0 0.0 4.3e-33 114.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 GAP90959.1 - 7e-17 61.3 1.5 0.00024 20.4 0.0 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAP90959.1 - 1e-13 51.9 0.2 0.0025 17.8 0.0 4.2 2 2 1 3 3 3 3 AAA domain ABC_ATPase PF09818.4 GAP90959.1 - 3.5e-09 35.7 1.4 0.0016 17.0 0.0 3.5 4 0 0 4 4 4 3 Predicted ATPase of the ABC class AAA_16 PF13191.1 GAP90959.1 - 9.3e-09 35.5 0.2 0.0004 20.4 0.0 3.1 3 1 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.1 GAP90959.1 - 1.6e-08 34.7 0.9 0.018 15.1 0.1 3.9 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 GAP90959.1 - 2.1e-08 35.0 0.0 0.012 16.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAP90959.1 - 7.7e-08 31.7 0.6 0.00015 21.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 GAP90959.1 - 1.3e-07 30.9 0.0 0.014 14.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 GAP90959.1 - 1e-06 28.2 0.2 0.011 15.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.1 GAP90959.1 - 1.1e-05 25.9 1.3 0.018 15.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 GAP90959.1 - 1.8e-05 24.3 0.6 0.011 15.4 0.0 3.5 3 0 0 3 3 2 1 Part of AAA domain AAA_30 PF13604.1 GAP90959.1 - 1.8e-05 24.3 0.3 0.53 9.8 0.0 3.7 4 0 0 4 4 4 2 AAA domain ATP-synt_ab PF00006.20 GAP90959.1 - 2.8e-05 23.7 0.0 0.018 14.5 0.0 2.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.1 GAP90959.1 - 4.3e-05 23.3 0.1 0.26 11.2 0.0 3.4 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA PF00004.24 GAP90959.1 - 9.6e-05 22.5 0.7 1.1 9.4 0.0 4.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 GAP90959.1 - 0.00019 21.1 0.0 0.33 10.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 GAP90959.1 - 0.00021 21.1 0.0 1.4 8.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 GAP90959.1 - 0.00039 19.9 0.9 0.17 11.2 0.0 4.0 4 0 0 4 4 4 1 AAA-like domain AAA_18 PF13238.1 GAP90959.1 - 0.00043 20.5 0.0 0.87 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 GAP90959.1 - 0.0011 18.6 0.2 0.73 9.5 0.0 3.0 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 GAP90959.1 - 0.0012 18.6 0.1 2.1 8.0 0.0 3.4 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 GAP90959.1 - 0.0076 16.1 0.0 1.2 9.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 GAP90959.1 - 0.0093 15.0 0.0 0.4 9.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 GAP90959.1 - 0.0097 15.5 0.0 0.6 9.7 0.0 2.7 2 0 0 2 2 2 1 NACHT domain DEAD PF00270.24 GAP90959.1 - 0.02 14.4 0.9 26 4.2 0.1 3.8 2 2 0 2 2 2 0 DEAD/DEAH box helicase PRK PF00485.13 GAP90959.1 - 0.022 14.3 0.0 3.5 7.1 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.17 GAP90959.1 - 0.023 14.8 0.0 11 6.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.7 GAP90959.1 - 0.024 13.7 0.4 2.7 7.0 0.0 2.9 3 0 0 3 3 2 0 Zeta toxin AAA_28 PF13521.1 GAP90959.1 - 0.026 14.4 0.1 3.2 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 GAP90959.1 - 0.034 13.7 0.0 6.9 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 GAP90959.1 - 0.056 12.3 1.1 4.7 5.9 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain Rad17 PF03215.10 GAP90959.1 - 0.056 12.1 0.0 1.3 7.5 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein MMR_HSR1 PF01926.18 GAP90959.1 - 0.068 13.1 0.1 21 5.0 0.0 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase Miro PF08477.8 GAP90959.1 - 0.071 13.6 0.3 15 6.1 0.0 3.2 3 0 0 3 3 3 0 Miro-like protein ATP_bind_1 PF03029.12 GAP90959.1 - 0.073 12.6 0.1 3.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF87 PF01935.12 GAP90959.1 - 0.085 12.6 0.1 0.69 9.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 KaiC PF06745.8 GAP90959.1 - 0.14 11.2 0.9 4 6.4 0.0 2.8 3 0 0 3 3 3 0 KaiC Arch_ATPase PF01637.13 GAP90959.1 - 0.29 10.8 0.6 11 5.6 0.0 2.7 3 0 0 3 3 2 0 Archaeal ATPase FSH1 PF03959.8 GAP90960.1 - 2e-31 109.0 0.0 3.7e-31 108.2 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) ketoacyl-synt PF00109.21 GAP90961.1 - 3.5e-74 249.5 0.0 7.7e-74 248.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 GAP90961.1 - 1e-60 204.5 0.4 3.4e-60 202.8 0.3 2.0 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 GAP90961.1 - 1.1e-58 199.1 0.0 1.8e-58 198.3 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 GAP90961.1 - 1.2e-50 171.7 1.1 7.2e-50 169.1 0.5 2.7 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 GAP90961.1 - 1.6e-43 149.0 0.0 3e-43 148.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 GAP90961.1 - 7.7e-39 132.2 0.0 3.5e-38 130.0 0.0 2.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 GAP90961.1 - 8.7e-16 57.6 0.1 5e-15 55.1 0.0 2.4 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAP90961.1 - 1.4e-12 48.6 0.0 9.2e-12 45.9 0.0 2.5 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP90961.1 - 3.8e-08 33.0 0.1 3.8e-08 33.0 0.1 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 GAP90961.1 - 0.001 18.0 0.1 0.0037 16.2 0.0 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain PP-binding PF00550.20 GAP90961.1 - 0.0024 18.1 0.3 0.0055 16.9 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site NmrA PF05368.8 GAP90961.1 - 0.017 14.3 0.3 0.038 13.2 0.2 1.5 1 0 0 1 1 1 0 NmrA-like family Shikimate_DH PF01488.15 GAP90961.1 - 0.054 13.5 0.2 0.2 11.7 0.2 2.0 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1205 PF06722.7 GAP90961.1 - 0.096 12.9 0.1 0.44 10.8 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1205) Phytase PF02333.10 GAP90962.1 - 6.2e-52 176.5 3.3 2.5e-51 174.6 0.7 2.1 2 0 0 2 2 2 1 Phytase EGF_2 PF07974.8 GAP90962.1 - 0.00027 21.0 29.7 0.039 14.1 10.8 2.5 2 0 0 2 2 2 2 EGF-like domain AA_permease PF00324.16 GAP90963.1 - 2.8e-102 342.5 44.0 3.5e-102 342.2 30.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAP90963.1 - 4.7e-26 91.3 44.3 5.9e-26 90.9 30.7 1.1 1 0 0 1 1 1 1 Amino acid permease Aldo_ket_red PF00248.16 GAP90964.1 - 1.5e-75 253.6 0.0 1.7e-75 253.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4470 PF14737.1 GAP90965.1 - 6.1e-24 83.6 0.0 1.6e-23 82.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 GAP90965.1 - 1.4e-08 34.4 10.5 4.1e-08 32.9 7.3 1.8 1 0 0 1 1 1 1 MYND finger HSBP1 PF06825.7 GAP90965.1 - 0.013 15.0 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Transp_cyt_pur PF02133.10 GAP90966.1 - 1e-31 109.9 28.3 1.9e-31 109.1 19.6 1.4 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2208 PF09973.4 GAP90966.1 - 0.26 10.4 3.3 4.6 6.4 0.3 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) MFS_1 PF07690.11 GAP90967.1 - 5.5e-44 150.3 36.2 5.5e-44 150.3 25.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP90967.1 - 4.4e-10 38.7 30.1 1.3e-09 37.1 20.9 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 GAP90967.1 - 0.0036 15.5 7.7 0.006 14.8 5.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SGL PF08450.7 GAP90968.1 - 0.00018 20.9 0.0 0.00085 18.7 0.0 1.9 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Phage_capsid PF05065.8 GAP90969.1 - 0.13 11.3 4.1 0.37 9.9 2.8 1.8 1 1 0 1 1 1 0 Phage capsid family DUF3268 PF11672.3 GAP90970.1 - 0.018 15.1 0.7 0.023 14.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3268) zf-FPG_IleRS PF06827.9 GAP90970.1 - 0.087 12.4 0.6 11 5.7 0.1 2.2 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS DNA_primase_lrg PF04104.9 GAP90971.1 - 2.2e-78 263.1 0.0 3e-78 262.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Clr5 PF14420.1 GAP90972.1 - 1.6e-20 72.7 0.7 5.3e-20 71.0 0.5 2.0 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.1 GAP90972.1 - 0.042 13.7 0.6 0.2 11.6 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Pyr_redox_3 PF13738.1 GAP90974.1 - 9.6e-27 94.3 0.0 9.3e-26 91.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAP90974.1 - 1.5e-13 49.7 0.0 2.6e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 GAP90974.1 - 5.9e-09 35.2 0.0 2e-07 30.2 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 GAP90974.1 - 9e-08 32.0 0.0 2.3e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAP90974.1 - 1.7e-06 28.0 0.0 1e-05 25.5 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAP90974.1 - 0.0023 17.7 4.0 0.022 14.5 0.0 3.5 3 1 1 4 4 4 1 FAD-NAD(P)-binding Pkinase PF00069.20 GAP90975.1 - 6.1e-48 163.2 0.0 2e-47 161.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP90975.1 - 1e-25 90.2 0.0 2.8e-25 88.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP90975.1 - 0.11 11.4 0.0 1.4 7.7 0.0 2.1 2 0 0 2 2 2 0 Kinase-like KAR9 PF08580.5 GAP90975.1 - 1.3 7.1 9.0 2.4 6.2 6.2 1.3 1 0 0 1 1 1 0 Yeast cortical protein KAR9 FAD_binding_3 PF01494.14 GAP90976.1 - 1.3e-06 27.6 1.6 3.7e-05 22.9 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Ank_2 PF12796.2 GAP90977.1 - 6.4e-31 106.5 0.2 4e-14 52.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAP90977.1 - 6.9e-26 88.7 0.5 1.9e-05 24.2 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.1 GAP90977.1 - 6.3e-23 78.5 4.8 0.00027 20.8 0.0 6.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 GAP90977.1 - 2.7e-22 78.6 0.9 1.2e-07 32.0 0.0 4.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) CorA PF01544.13 GAP90977.1 - 1.5e-18 66.8 0.0 2.3e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Ank_5 PF13857.1 GAP90977.1 - 2.2e-16 59.5 0.8 8.4e-07 29.0 0.1 4.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DUF1843 PF08898.5 GAP90977.1 - 2e-05 24.5 0.1 0.00064 19.7 0.0 2.6 1 1 1 2 2 2 1 Domain of unknown function (DUF1843) Na_H_Exchanger PF00999.16 GAP90977.1 - 0.16 10.4 1.0 0.22 10.0 0.7 1.1 1 0 0 1 1 1 0 Sodium/hydrogen exchanger family PBP1_TM PF14812.1 GAP90978.1 - 0.04 14.2 1.2 0.43 10.9 0.0 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ank_2 PF12796.2 GAP90979.1 - 3.1e-52 174.8 5.0 6.3e-16 58.4 0.0 5.0 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) SPX PF03105.14 GAP90979.1 - 5.4e-30 105.1 12.3 3.9e-17 62.9 2.7 2.3 1 1 1 2 2 2 2 SPX domain Ank_4 PF13637.1 GAP90979.1 - 2.4e-28 98.0 4.9 3.3e-09 37.0 0.0 5.7 4 1 3 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.25 GAP90979.1 - 1.2e-25 87.9 11.3 8.3e-06 25.3 0.0 7.3 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 GAP90979.1 - 6.7e-20 70.6 13.0 1.2e-08 34.8 0.1 7.7 4 1 5 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP90979.1 - 7.2e-19 66.0 5.6 0.0023 17.9 0.1 7.0 7 0 0 7 7 7 4 Ankyrin repeat GDPD PF03009.12 GAP90979.1 - 8.4e-10 38.5 0.0 1.2e-08 34.8 0.0 2.8 3 1 0 3 3 3 1 Glycerophosphoryl diester phosphodiesterase family Rsa3 PF14615.1 GAP90979.1 - 0.057 12.7 1.8 1.8 7.8 0.2 2.9 2 0 0 2 2 2 0 Ribosome-assembly protein 3 p450 PF00067.17 GAP90980.1 - 8.8e-66 222.3 0.0 1.2e-65 221.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CUE PF02845.11 GAP90981.1 - 5.1e-11 41.8 0.0 8.5e-11 41.1 0.0 1.3 1 0 0 1 1 1 1 CUE domain OB_NTP_bind PF07717.11 GAP90982.1 - 2.3e-24 85.4 0.0 4.4e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 GAP90982.1 - 6.9e-21 74.1 0.0 3e-20 72.1 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 GAP90982.1 - 5.1e-12 45.4 0.0 1.1e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 GAP90982.1 - 0.00027 21.0 0.0 0.00062 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 GAP90982.1 - 0.041 13.3 0.2 0.36 10.2 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 GAP90982.1 - 0.064 12.1 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 GAP90982.1 - 0.078 12.0 1.3 0.28 10.2 0.1 2.4 2 1 1 3 3 3 0 Zeta toxin SKG6 PF08693.5 GAP90983.1 - 0.0004 19.6 0.0 0.00063 19.0 0.0 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SKG6 PF08693.5 GAP90984.1 - 1e-11 43.9 0.1 3.6e-11 42.1 0.1 2.0 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 GAP90984.1 - 0.0019 17.7 0.3 0.0052 16.2 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) CcmD PF04995.9 GAP90984.1 - 0.052 13.2 0.5 0.088 12.5 0.3 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Rifin_STEVOR PF02009.11 GAP90984.1 - 0.19 11.3 0.0 0.39 10.3 0.0 1.4 1 1 0 1 1 1 0 Rifin/stevor family Ndc1_Nup PF09531.5 GAP90984.1 - 7.6 4.8 14.8 11 4.2 10.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup COesterase PF00135.23 GAP90985.1 - 9e-88 295.2 0.0 1.2e-87 294.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAP90985.1 - 1.6e-06 27.8 0.2 3.9e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold DASH_Dad2 PF08654.5 GAP90987.1 - 3e-32 110.6 1.0 4e-32 110.2 0.7 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad2 Seryl_tRNA_N PF02403.17 GAP90987.1 - 0.069 13.1 1.7 0.07 13.1 0.2 1.7 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Snapin_Pallidin PF14712.1 GAP90987.1 - 0.2 12.0 3.8 0.93 9.8 0.9 2.4 2 1 0 2 2 2 0 Snapin/Pallidin Shugoshin_N PF07558.6 GAP90988.1 - 7.4e-14 51.1 8.0 1.8e-13 49.9 5.6 1.7 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 GAP90988.1 - 3.3e-11 42.4 4.5 1.8e-10 40.1 3.1 2.4 1 0 0 1 1 1 1 Shugoshin C terminus HALZ PF02183.13 GAP90988.1 - 0.036 13.7 1.8 0.078 12.7 1.3 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF972 PF06156.8 GAP90988.1 - 3.3 8.0 5.2 1.4 9.3 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Metallophos_2 PF12850.2 GAP90989.1 - 4.9e-13 49.2 0.0 5.9e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 GAP90989.1 - 0.15 11.4 0.1 1.1 8.6 0.0 2.0 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase Aminotran_5 PF00266.14 GAP90990.1 - 2.9e-27 95.3 0.0 3.7e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 GAP90990.1 - 0.0032 17.3 0.1 0.036 13.9 0.0 2.4 2 1 0 2 2 2 1 B12 binding domain CRM1_C PF08767.6 GAP90991.1 - 4e-127 423.5 1.1 4e-127 423.5 0.8 3.0 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 GAP90991.1 - 1.3e-40 138.6 10.7 3e-40 137.5 4.7 3.6 3 1 1 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 GAP90991.1 - 1.9e-12 46.8 1.9 4.7e-12 45.6 0.0 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain DUF3385 PF11865.3 GAP90991.1 - 0.051 13.5 2.3 0.11 12.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.2 GAP90991.1 - 0.052 13.9 1.8 4.1 7.8 0.0 4.2 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region C8 PF08742.6 GAP90991.1 - 0.14 12.4 1.0 1 9.6 0.0 2.8 3 0 0 3 3 3 0 C8 domain Fungal_trans_2 PF11951.3 GAP90992.1 - 1.2e-33 116.2 0.6 1.5e-33 115.9 0.4 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1464 PF07318.7 GAP90992.1 - 0.014 14.2 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) SR-25 PF10500.4 GAP90992.1 - 4.8 6.5 10.5 7.8 5.8 7.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PPE PF00823.14 GAP90992.1 - 7.7 6.3 11.9 17 5.2 0.0 3.2 2 1 1 3 3 3 0 PPE family NmrA PF05368.8 GAP90993.1 - 1.2e-23 83.5 0.0 1.5e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAP90993.1 - 2e-18 67.0 0.4 2.7e-18 66.6 0.3 1.2 1 0 0 1 1 1 1 NADH(P)-binding HTH_psq PF05225.11 GAP90993.1 - 0.02 14.4 0.3 0.27 10.8 0.0 2.7 3 0 0 3 3 3 0 helix-turn-helix, Psq domain Abhydrolase_3 PF07859.8 GAP90994.1 - 2.1e-21 76.4 0.0 2.8e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 GAP90994.1 - 2.5e-15 56.0 0.0 3e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) DUF997 PF06196.7 GAP90994.1 - 0.14 11.6 0.7 1.9 8.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF997) Aldolase_II PF00596.16 GAP90997.1 - 3.9e-41 140.6 0.9 5e-41 140.3 0.6 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Cpn60_TCP1 PF00118.19 GAP90998.1 - 3.4e-162 540.4 0.5 3.9e-162 540.2 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1168 PF06658.7 GAP90999.1 - 6.6e-34 116.4 12.1 6.6e-34 116.4 8.4 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1168) Chorion_3 PF05387.6 GAP90999.1 - 2 7.7 10.1 1 8.7 5.2 1.6 2 0 0 2 2 2 0 Chorion family 3 His_Phos_1 PF00300.17 GAP91000.1 - 6.8e-33 113.9 0.0 1.3e-32 113.0 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) EcKinase PF02958.15 GAP91002.1 - 2.1e-16 59.9 0.0 1.8e-14 53.6 0.0 2.1 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 GAP91002.1 - 1.5e-08 34.6 1.9 2.1e-08 34.2 1.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 GAP91002.1 - 2.6e-08 32.9 0.0 3.6e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) NTP_transf_3 PF12804.2 GAP91002.1 - 0.029 14.4 0.2 0.075 13.1 0.1 1.7 2 0 0 2 2 2 0 MobA-like NTP transferase domain Terpene_synth_C PF03936.11 GAP91004.1 - 0.00021 20.6 0.1 0.00029 20.1 0.1 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DUF1080 PF06439.6 GAP91004.1 - 0.08 12.8 0.7 11 5.8 0.2 2.3 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1080) HATPase_c PF02518.21 GAP91005.1 - 6.9e-23 80.4 0.2 1.6e-22 79.3 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAP91005.1 - 3.6e-22 78.4 0.0 8.1e-22 77.3 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 GAP91005.1 - 2.8e-21 75.2 0.2 1.2e-20 73.2 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 GAP91005.1 - 3.7e-19 68.6 1.2 5.5e-10 39.2 0.5 3.6 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.1 GAP91005.1 - 1.4e-15 57.5 0.0 3.1e-08 33.9 0.0 3.6 2 1 0 2 2 2 2 PAS domain PAS_4 PF08448.5 GAP91005.1 - 3.1e-08 33.6 0.3 2.3e-07 30.8 0.1 2.7 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 GAP91005.1 - 4.3e-06 26.4 0.0 0.14 11.9 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.1 GAP91005.1 - 0.11 12.4 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 PAS domain Arylsulfotran_2 PF14269.1 GAP91006.1 - 1.1e-45 156.0 0.1 1.6e-45 155.5 0.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 GAP91006.1 - 9.7e-18 63.9 0.3 2e-17 62.9 0.2 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ PF01011.16 GAP91006.1 - 0.098 12.2 0.7 0.54 9.8 0.0 2.7 2 0 0 2 2 2 0 PQQ enzyme repeat Peptidase_M13_N PF05649.8 GAP91007.1 - 3.3e-83 279.9 0.0 4.5e-83 279.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 GAP91007.1 - 1.4e-55 187.7 0.0 2.2e-55 187.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Sensor PF13796.1 GAP91007.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative sensor Cytochrom_B561 PF03188.11 GAP91008.1 - 6.3e-18 64.9 9.2 6.3e-18 64.9 6.4 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF998 PF06197.8 GAP91008.1 - 0.0054 16.0 15.2 0.054 12.8 2.0 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF998) DUF4149 PF13664.1 GAP91008.1 - 0.008 16.2 2.7 0.008 16.2 1.9 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4149) DUF2306 PF10067.4 GAP91008.1 - 0.0097 16.0 0.3 0.0097 16.0 0.2 3.3 2 1 0 3 3 3 1 Predicted membrane protein (DUF2306) PepSY_TM_1 PF13172.1 GAP91008.1 - 0.12 12.2 0.1 0.12 12.2 0.1 3.5 3 0 0 3 3 3 0 PepSY-associated TM helix Cytochrom_B_C PF00032.12 GAP91008.1 - 0.22 11.7 4.6 0.98 9.6 0.2 2.6 2 1 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD DUF4079 PF13301.1 GAP91008.1 - 2.1 8.2 18.1 3.5 7.6 3.5 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) Allantoicase PF03561.10 GAP91009.1 - 1.4e-106 352.4 0.0 1.8e-57 193.0 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat DIL PF01843.14 GAP91010.1 - 1.7e-18 66.4 3.4 2.4e-16 59.4 2.4 2.7 1 1 0 1 1 1 1 DIL domain Ank_2 PF12796.2 GAP91010.1 - 9.6e-17 61.1 0.1 3e-16 59.5 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAP91010.1 - 4.2e-16 57.8 0.2 7.2e-07 28.7 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 GAP91010.1 - 5.3e-13 49.0 0.1 1.9e-05 25.0 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP91010.1 - 1.5e-11 44.1 0.0 1.5e-05 25.0 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP91010.1 - 8.6e-09 34.8 1.0 0.032 14.4 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat HMD PF03201.11 GAP91010.1 - 0.17 11.7 0.3 17 5.3 0.0 3.1 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase RabGAP-TBC PF00566.13 GAP91011.1 - 1.2e-33 116.4 0.0 2.1e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Herpes_LMP2 PF07415.6 GAP91012.1 - 0.094 11.2 2.4 2.1 6.8 0.2 2.1 2 0 0 2 2 2 0 Gammaherpesvirus latent membrane protein (LMP2) protein Phage_min_cap2 PF06152.6 GAP91012.1 - 3.3 6.5 6.4 5.1 5.9 4.5 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 zf-RING_2 PF13639.1 GAP91013.1 - 1.5e-06 27.9 1.2 1.5e-06 27.9 0.8 3.1 4 0 0 4 4 4 1 Ring finger domain Pellino PF04710.9 GAP91013.1 - 0.0069 15.0 0.1 0.013 14.1 0.0 1.3 1 0 0 1 1 1 1 Pellino zf-C3HC4_2 PF13923.1 GAP91013.1 - 0.0085 16.1 1.3 0.0085 16.1 0.9 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAP91013.1 - 0.13 11.9 5.8 0.077 12.6 1.2 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zip PF02535.17 GAP91013.1 - 9.7 5.0 30.4 0.096 11.6 9.9 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Meth_synt_2 PF01717.13 GAP91015.1 - 1.8e-142 474.1 0.0 3.4e-136 453.4 0.0 3.3 3 1 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 GAP91015.1 - 2e-122 408.3 0.1 2.1e-110 368.8 0.0 3.2 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain CENP-Q PF13094.1 GAP91017.1 - 0.00042 20.3 1.1 0.05 13.6 0.0 2.2 1 1 1 2 2 2 2 CENP-Q, a CENPA-CAD centromere complex subunit CENP-Q PF13094.1 GAP91018.1 - 0.0074 16.3 0.2 0.0074 16.3 0.1 2.4 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Cnl2_NKP2 PF09447.5 GAP91020.1 - 9.6e-25 86.0 0.4 2.1e-24 84.9 0.3 1.6 1 0 0 1 1 1 1 Cnl2/NKP2 family protein Syntaxin_2 PF14523.1 GAP91020.1 - 0.04 13.9 1.2 0.12 12.3 0.0 2.1 2 1 0 2 2 2 0 Syntaxin-like protein STAT_alpha PF01017.15 GAP91020.1 - 0.08 12.6 0.4 11 5.6 0.0 2.3 2 0 0 2 2 2 0 STAT protein, all-alpha domain Reo_sigmaC PF04582.7 GAP91020.1 - 0.12 11.5 0.4 0.29 10.2 0.1 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Tudor-knot PF11717.3 GAP91021.1 - 4.4e-09 35.9 2.3 7.5e-09 35.1 1.6 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 GAP91021.1 - 0.0036 16.9 0.8 0.0059 16.2 0.5 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PWWP PF00855.12 GAP91021.1 - 0.077 13.2 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 PWWP domain MRG PF05712.8 GAP91022.1 - 7.4e-45 152.2 0.0 8.7e-45 152.0 0.0 1.0 1 0 0 1 1 1 1 MRG Ribosomal_L30 PF00327.15 GAP91023.1 - 5.8e-17 61.0 0.1 7.3e-17 60.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Citrate_synt PF00285.16 GAP91024.1 - 1.7e-19 69.8 0.0 9.6e-17 60.7 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase CoA_binding PF02629.14 GAP91024.1 - 1.5e-18 67.0 0.2 4.4e-18 65.5 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 GAP91024.1 - 1.1e-14 54.3 0.2 2.1e-14 53.3 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 GAP91024.1 - 1e-07 31.6 0.1 8.2e-06 25.4 0.0 2.4 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 GAP91024.1 - 0.084 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain ATP-grasp_2 PF08442.5 GAP91025.1 - 3.6e-08 33.0 0.0 5.5e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Beta-lactamase PF00144.19 GAP91026.1 - 8.6e-33 113.7 0.0 1e-32 113.5 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase TPR_12 PF13424.1 GAP91027.1 - 8.2e-37 125.0 16.1 7.8e-13 48.1 0.4 5.8 3 1 2 6 6 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 GAP91027.1 - 1.2e-29 101.2 14.6 3.7e-05 23.5 0.1 7.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_4 PF07721.9 GAP91027.1 - 8.5e-10 38.1 11.4 0.27 11.7 0.1 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 GAP91027.1 - 3e-09 36.3 1.9 0.23 11.1 0.0 5.6 2 1 4 6 6 6 4 TPR repeat TPR_16 PF13432.1 GAP91027.1 - 4.7e-09 36.6 2.3 0.099 13.3 0.0 5.5 3 3 2 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAP91027.1 - 1.5e-08 33.7 8.1 0.19 11.6 0.1 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 GAP91027.1 - 2.1e-08 34.3 12.3 0.093 13.0 0.1 6.7 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAP91027.1 - 3.5e-07 29.6 13.4 1.3 9.0 0.0 8.0 9 0 0 9 9 9 2 Tetratricopeptide repeat AAA_22 PF13401.1 GAP91027.1 - 1.2e-06 28.6 0.0 7.3e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain TPR_1 PF00515.23 GAP91027.1 - 5.7e-06 25.7 2.1 2.9 7.6 0.1 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAP91027.1 - 9.6e-06 25.0 0.5 16 5.5 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_21 PF09976.4 GAP91027.1 - 0.00017 21.5 0.0 0.0046 16.9 0.0 2.9 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAP91027.1 - 0.00065 20.1 18.2 1.9 9.3 0.0 8.5 11 0 0 11 11 8 1 Tetratricopeptide repeat NACHT PF05729.7 GAP91027.1 - 0.0021 17.7 0.0 0.0079 15.8 0.0 2.0 1 0 0 1 1 1 1 NACHT domain TPR_6 PF13174.1 GAP91027.1 - 0.0031 17.8 2.0 72 4.1 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat NB-ARC PF00931.17 GAP91027.1 - 0.0034 16.3 0.6 0.1 11.4 0.0 2.7 2 1 0 2 2 2 1 NB-ARC domain Apc3 PF12895.2 GAP91027.1 - 0.0059 16.7 0.6 6.4 6.9 0.1 4.8 3 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 GAP91027.1 - 0.0083 16.2 2.8 9.4 6.7 0.0 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 GAP91027.1 - 0.024 14.7 0.2 44 4.2 0.0 4.0 2 1 1 3 3 3 0 Tetratricopeptide repeat Viral_helicase1 PF01443.13 GAP91027.1 - 0.072 12.6 0.1 0.27 10.7 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 GAP91027.1 - 0.1 11.7 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Arch_ATPase PF01637.13 GAP91027.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase RPN7 PF10602.4 GAP91027.1 - 0.17 11.2 2.1 7.6 5.8 0.0 3.7 5 0 0 5 5 5 0 26S proteasome subunit RPN7 Miro PF08477.8 GAP91027.1 - 0.17 12.4 0.0 0.43 11.0 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein p450 PF00067.17 GAP91028.1 - 7.3e-58 196.1 0.0 9.7e-58 195.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_U49 PF10463.4 GAP91028.1 - 0.21 11.3 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase U49 DUF676 PF05057.9 GAP91029.1 - 0.00012 21.4 0.2 0.00022 20.6 0.2 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 GAP91029.1 - 0.0097 15.8 0.1 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAP91029.1 - 0.018 14.6 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.2 GAP91029.1 - 0.059 13.1 0.0 0.14 11.8 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Tyrosinase PF00264.15 GAP91030.1 - 2e-28 100.0 0.3 2.9e-28 99.5 0.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Tol_Tol_Ttg2 PF05494.7 GAP91030.1 - 0.012 15.2 0.0 0.043 13.3 0.0 1.7 2 0 0 2 2 2 0 Toluene tolerance, Ttg2 AA_permease_2 PF13520.1 GAP91031.1 - 3.6e-44 150.9 48.8 4.6e-44 150.6 33.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAP91031.1 - 9.6e-26 90.1 43.7 1.2e-25 89.8 30.3 1.0 1 0 0 1 1 1 1 Amino acid permease zf-C2H2 PF00096.21 GAP91032.1 - 1.1e-10 41.2 13.4 2.1e-06 27.7 3.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP91032.1 - 1.7e-08 34.2 11.7 5.3e-05 23.2 2.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAP91032.1 - 3.2e-07 30.2 12.5 6.9e-05 22.9 2.5 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2HC_2 PF13913.1 GAP91032.1 - 0.0023 17.5 2.1 0.0023 17.5 1.4 1.8 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 GAP91032.1 - 0.0093 16.0 3.8 0.016 15.3 0.5 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 GAP91032.1 - 0.014 15.5 4.3 0.023 14.7 3.0 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_3 PF14369.1 GAP91032.1 - 0.019 14.9 1.3 1.8 8.6 0.1 2.5 2 0 0 2 2 2 0 zinc-finger zf-UBR PF02207.15 GAP91032.1 - 0.056 13.1 2.1 0.1 12.3 1.5 1.3 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) UPF0547 PF10571.4 GAP91032.1 - 0.11 12.1 0.1 0.11 12.1 0.1 1.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-C2H2_2 PF12756.2 GAP91032.1 - 0.4 10.8 4.1 1.7 8.7 0.6 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 GAP91032.1 - 0.73 9.8 6.5 3.9 7.5 0.5 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4636 PF15468.1 GAP91032.1 - 1.4 8.2 5.1 1.1 8.6 2.3 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4636) zf-H2C2_5 PF13909.1 GAP91032.1 - 2.6 8.4 5.8 18 5.8 1.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain WD40 PF00400.27 GAP91033.1 - 2.3e-29 100.1 10.4 8.3e-11 41.3 0.2 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Gmad1 PF10647.4 GAP91033.1 - 2.6e-05 23.7 2.9 0.00028 20.3 0.1 2.2 2 0 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Nbas_N PF15492.1 GAP91033.1 - 0.00058 19.0 0.2 2 7.4 0.0 3.5 1 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.6 GAP91033.1 - 0.00076 19.2 0.0 0.017 14.8 0.0 2.7 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 GAP91033.1 - 0.019 13.2 0.6 0.13 10.5 0.1 2.1 2 1 1 3 3 3 0 Cytochrome D1 heme domain Pyridox_oxidase PF01243.15 GAP91033.1 - 0.046 13.7 0.0 0.85 9.6 0.0 2.6 1 1 1 2 2 2 0 Pyridoxamine 5'-phosphate oxidase DUF4265 PF14085.1 GAP91033.1 - 0.15 11.8 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) Septin PF00735.13 GAP91034.1 - 1.6e-112 375.1 0.6 1.9e-112 374.8 0.4 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 GAP91034.1 - 1.3e-06 28.3 0.0 2.1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 GAP91034.1 - 1.6e-05 24.1 0.0 3.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 GAP91034.1 - 2.3e-05 23.9 0.3 0.0019 17.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 GAP91034.1 - 8.3e-05 21.8 0.0 0.00015 20.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 GAP91034.1 - 0.00088 19.1 0.3 1.1 9.0 0.1 2.5 1 1 1 2 2 2 2 Dynamin family AAA_10 PF12846.2 GAP91034.1 - 0.0026 17.2 0.0 0.0028 17.1 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 GAP91034.1 - 0.009 16.3 0.4 0.02 15.1 0.2 1.7 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 GAP91034.1 - 0.01 15.9 0.0 0.028 14.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 GAP91034.1 - 0.027 13.6 0.1 0.16 11.1 0.0 2.0 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 GAP91034.1 - 0.028 14.3 0.0 0.061 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.17 GAP91034.1 - 0.031 13.1 0.0 0.063 12.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain FtsK_SpoIIIE PF01580.13 GAP91034.1 - 0.041 13.3 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.1 GAP91034.1 - 0.042 14.1 0.1 0.071 13.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 GAP91034.1 - 0.051 12.4 0.0 0.1 11.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 GAP91034.1 - 0.15 11.5 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Guanylate_kin PF00625.16 GAP91035.1 - 8.3e-61 204.6 0.0 9.6e-61 204.4 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase DUF258 PF03193.11 GAP91035.1 - 6.1e-06 25.5 0.0 7.6e-05 21.9 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAP91035.1 - 7.8e-05 22.8 0.0 0.00064 19.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 GAP91035.1 - 8.2e-05 22.5 0.0 0.00034 20.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 GAP91035.1 - 0.00018 21.4 0.0 0.0097 15.8 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 GAP91035.1 - 0.00057 20.2 0.1 0.0034 17.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAP91035.1 - 0.001 19.0 0.0 0.0013 18.7 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 GAP91035.1 - 0.0033 18.2 0.0 0.0069 17.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 GAP91035.1 - 0.013 15.9 0.0 0.033 14.6 0.0 1.7 1 1 1 2 2 2 0 Miro-like protein AAA_28 PF13521.1 GAP91035.1 - 0.015 15.2 0.3 0.62 10.0 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.1 GAP91035.1 - 0.017 15.0 0.0 0.031 14.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 GAP91035.1 - 0.018 14.6 0.1 0.074 12.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 GAP91035.1 - 0.08 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.10 GAP91035.1 - 0.13 10.9 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Glyco_hydro_72 PF03198.9 GAP91036.1 - 1.2e-115 385.8 0.1 1.4e-115 385.5 0.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase zf-C2H2 PF00096.21 GAP91037.1 - 8.2e-10 38.4 9.4 0.00022 21.3 0.6 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type Fungal_trans PF04082.13 GAP91037.1 - 3.1e-08 32.8 0.2 5.9e-08 31.9 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP91037.1 - 2.2e-06 27.4 12.2 5.8e-06 26.1 8.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 GAP91037.1 - 1.1e-05 25.3 8.0 0.00028 20.9 0.8 3.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAP91037.1 - 0.0088 16.2 2.0 0.0088 16.2 1.4 3.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 GAP91037.1 - 0.031 14.4 4.7 1.1 9.4 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAP91037.1 - 0.087 13.0 1.4 4 7.7 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type NmrA PF05368.8 GAP91038.1 - 1.7e-25 89.6 0.2 2.5e-25 89.1 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAP91038.1 - 1.1e-14 54.9 1.4 3.5e-14 53.2 0.3 1.9 1 1 1 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 GAP91038.1 - 2.6e-05 23.8 0.1 0.00012 21.6 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 GAP91038.1 - 0.00023 20.2 0.1 0.00039 19.5 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 GAP91038.1 - 0.0013 17.6 0.0 0.0026 16.7 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 GAP91038.1 - 0.0014 17.4 0.6 0.1 11.3 0.1 2.7 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 GAP91038.1 - 0.013 14.4 0.5 0.038 12.8 0.1 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain DapB_N PF01113.15 GAP91038.1 - 0.047 13.6 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 GAP91038.1 - 0.051 13.8 0.5 0.13 12.6 0.1 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain PAF-AH_p_II PF03403.8 GAP91039.1 - 9.2e-38 129.5 0.0 3.6e-31 107.7 0.0 2.0 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 GAP91039.1 - 4.6e-11 42.6 0.0 1e-10 41.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP91039.1 - 1.9e-06 27.9 0.0 4.9e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 GAP91039.1 - 3.5e-05 22.8 0.0 0.0024 16.8 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase enzyme Hydrolase_4 PF12146.3 GAP91039.1 - 0.0005 19.8 0.6 0.0013 18.5 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Chlorophyllase PF07224.6 GAP91039.1 - 0.0034 16.2 0.0 0.0071 15.1 0.0 1.4 2 0 0 2 2 2 1 Chlorophyllase WD40_alt PF14077.1 GAP91039.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif EcKinase PF02958.15 GAP91040.1 - 0.065 12.3 0.1 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase DNA_pol_delta_4 PF04081.8 GAP91041.1 - 4.3e-28 98.0 0.9 6.4e-28 97.5 0.6 1.3 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 TBX PF12598.3 GAP91041.1 - 0.026 14.9 5.6 0.048 14.0 3.9 1.4 1 0 0 1 1 1 0 T-box transcription factor DUF2419 PF10343.4 GAP91042.1 - 5e-108 360.7 0.0 6.1e-108 360.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) ThiF PF00899.16 GAP91043.1 - 2.3e-42 144.0 0.1 4.5e-42 143.1 0.1 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 GAP91043.1 - 1.5e-31 107.7 1.3 3.2e-31 106.6 0.1 2.1 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 GAP91043.1 - 7.2e-21 74.0 0.3 7.2e-21 74.0 0.2 1.8 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 GAP91043.1 - 1.3e-18 66.1 0.5 1.3e-18 66.1 0.4 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 GAP91043.1 - 0.00051 20.1 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 GAP91043.1 - 0.0011 19.1 0.1 0.0028 17.8 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding DivIC PF04977.10 GAP91043.1 - 0.28 10.7 4.7 5.9 6.4 0.1 3.1 3 0 0 3 3 3 0 Septum formation initiator adh_short PF00106.20 GAP91044.1 - 3.8e-28 98.4 0.0 4.9e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP91044.1 - 9.3e-14 51.7 0.0 6.3e-09 35.9 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP91044.1 - 1.4e-10 41.1 0.1 2e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAP91044.1 - 0.0066 16.4 0.0 0.012 15.6 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAP91044.1 - 0.035 13.5 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 GAP91044.1 - 0.036 13.7 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KH_1 PF00013.24 GAP91044.1 - 0.075 12.6 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 KH domain THF_DHG_CYH_C PF02882.14 GAP91044.1 - 0.11 11.5 0.0 0.5 9.4 0.0 2.1 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain zf-Mss51 PF13824.1 GAP91045.1 - 3e-28 97.4 5.3 6.4e-28 96.3 3.7 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 GAP91045.1 - 0.0047 16.7 0.7 0.0047 16.7 0.5 2.1 2 0 0 2 2 2 1 MYND finger GFA PF04828.9 GAP91045.1 - 0.034 14.0 0.6 0.31 11.0 0.0 2.3 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme CPSF_A PF03178.10 GAP91046.1 - 1.6e-103 346.2 0.0 2.8e-101 338.8 0.0 2.7 3 0 0 3 3 3 2 CPSF A subunit region MMS1_N PF10433.4 GAP91046.1 - 2.2e-66 224.0 0.0 4e-66 223.2 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.27 GAP91046.1 - 0.029 14.2 0.1 0.093 12.6 0.1 1.9 1 0 0 1 1 1 0 WD domain, G-beta repeat UBA_4 PF14555.1 GAP91047.1 - 0.00027 20.3 0.3 0.00056 19.3 0.2 1.5 1 0 0 1 1 1 1 UBA-like domain LysM PF01476.15 GAP91047.1 - 0.062 13.2 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 LysM domain HTH_psq PF05225.11 GAP91047.1 - 0.12 11.9 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 helix-turn-helix, Psq domain PH PF00169.24 GAP91048.1 - 2e-05 24.7 0.0 0.00012 22.2 0.0 2.5 1 0 0 1 1 1 1 PH domain GRAM PF02893.15 GAP91048.1 - 0.0074 15.7 0.0 0.019 14.5 0.0 1.7 1 0 0 1 1 1 1 GRAM domain DUF3074 PF11274.3 GAP91049.1 - 2.2e-52 177.3 0.2 8.5e-52 175.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) START PF01852.14 GAP91049.1 - 0.00043 19.6 0.0 0.014 14.7 0.0 2.3 2 0 0 2 2 2 1 START domain CAF-1_p150 PF11600.3 GAP91049.1 - 0.11 11.8 33.8 0.37 10.1 23.4 1.8 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal HlyD PF00529.15 GAP91049.1 - 0.88 8.8 18.0 1.5 8.0 12.5 1.3 1 0 0 1 1 1 0 HlyD family secretion protein Dicty_REP PF05086.7 GAP91049.1 - 2.4 5.7 7.1 3.5 5.2 4.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Cas_Csy1 PF09611.5 GAP91050.1 - 0.4 9.5 0.9 0.59 9.0 0.6 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy1) AIG1 PF04548.11 GAP91051.1 - 2.2e-11 43.3 0.1 3.4e-11 42.6 0.1 1.3 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 GAP91051.1 - 7e-06 25.9 0.0 1.7e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 GAP91051.1 - 0.00049 19.3 0.1 0.00081 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 GAP91051.1 - 0.00053 19.8 0.8 0.13 12.0 0.1 2.6 1 1 1 2 2 2 2 Dynamin family AAA_33 PF13671.1 GAP91051.1 - 0.0042 16.9 0.2 0.011 15.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain Septin PF00735.13 GAP91051.1 - 0.0046 16.0 0.2 0.017 14.1 0.1 2.0 2 1 0 2 2 2 1 Septin Miro PF08477.8 GAP91051.1 - 0.0068 16.9 0.3 0.033 14.6 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein AAA_17 PF13207.1 GAP91051.1 - 0.035 14.9 0.2 0.094 13.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 GAP91051.1 - 0.076 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 GAP91051.1 - 0.081 12.3 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain IncA PF04156.9 GAP91052.1 - 1.8e-05 24.4 42.2 0.0004 20.0 10.0 4.7 1 1 4 5 5 5 3 IncA protein Cast PF10174.4 GAP91052.1 - 0.0034 15.5 7.6 0.0034 15.5 5.3 4.0 1 1 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Reo_sigmaC PF04582.7 GAP91052.1 - 0.006 15.8 5.5 0.27 10.3 0.0 3.2 1 1 0 3 3 3 2 Reovirus sigma C capsid protein DUF1079 PF06435.6 GAP91052.1 - 0.53 10.2 28.2 5.8 6.9 0.3 7.1 6 0 0 6 6 6 0 Repeat of unknown function (DUF1079) Strep_SA_rep PF06696.6 GAP91052.1 - 3.3 7.5 11.6 9.4 6.1 0.1 4.7 4 0 0 4 4 4 0 Streptococcal surface antigen repeat DUF4200 PF13863.1 GAP91052.1 - 9.3 6.2 114.2 0.1 12.5 3.8 7.1 1 1 5 7 7 7 0 Domain of unknown function (DUF4200) Fungal_trans PF04082.13 GAP91055.1 - 7.9e-18 64.2 0.1 1.3e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 GAP91055.1 - 3.9e-09 36.3 13.6 0.00017 21.7 1.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAP91055.1 - 5.9e-06 26.3 7.4 5.9e-06 26.3 5.2 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAP91055.1 - 0.0051 17.0 17.7 0.12 12.8 2.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 GAP91055.1 - 0.09 13.0 1.3 0.23 11.7 0.9 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 GAP91055.1 - 1.5 9.0 4.4 0.42 10.8 0.4 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF2422 PF10337.4 GAP91056.1 - 1.9e-89 300.5 0.0 1.9e-89 300.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 GAP91056.1 - 5.3e-17 61.9 13.4 5.3e-17 61.9 9.3 2.8 3 0 0 3 3 3 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 GAP91056.1 - 0.00016 21.3 0.0 0.0015 18.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) ALMT PF11744.3 GAP91056.1 - 0.00024 19.8 7.3 0.0019 16.9 2.9 2.3 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC PF04632.7 GAP91056.1 - 5.5 5.2 16.1 3.4 5.9 0.9 2.9 2 1 1 3 3 3 0 Fusaric acid resistance protein family DUF4604 PF15377.1 GAP91057.1 - 0.93 9.6 9.5 1.2 9.3 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Peptidase_S49_N PF08496.5 GAP91057.1 - 1.3 8.8 4.6 1.4 8.7 3.2 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1639 PF07797.9 GAP91057.1 - 2.1 7.8 5.5 4.5 6.7 3.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) UPF0233 PF06781.7 GAP91057.1 - 2.1 8.0 3.8 1.6 8.3 0.7 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) Actino_peptide PF14408.1 GAP91057.1 - 5.6 6.9 6.6 8.5 6.3 1.9 2.0 1 1 1 2 2 2 0 Ribosomally synthesized peptide in actinomycetes RNase_H PF00075.19 GAP91058.1 - 0.051 13.9 0.0 0.22 11.8 0.0 1.8 1 1 1 2 2 2 0 RNase H RVT_3 PF13456.1 GAP91058.1 - 0.059 13.1 0.1 2.5 7.9 0.1 2.2 1 1 0 1 1 1 0 Reverse transcriptase-like HeLo PF14479.1 GAP91059.1 - 0.029 14.1 1.7 0.062 13.0 1.2 1.5 1 0 0 1 1 1 0 Prion-inhibition and propagation OmpH PF03938.9 GAP91059.1 - 0.34 10.8 2.4 0.67 9.8 1.7 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) zf-C2H2_4 PF13894.1 GAP91060.1 - 0.0037 17.4 19.1 0.058 13.7 0.4 4.8 4 1 0 4 4 4 3 C2H2-type zinc finger Opi1 PF08618.5 GAP91060.1 - 0.028 13.3 0.2 0.041 12.8 0.1 1.2 1 0 0 1 1 1 0 Transcription factor Opi1 zf-Di19 PF05605.7 GAP91060.1 - 0.35 11.0 4.9 7.9 6.6 0.2 3.5 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding UDPGT PF00201.13 GAP91061.1 - 2.2e-07 29.8 0.0 4e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.15 GAP91061.1 - 0.0026 17.5 0.3 0.0026 17.5 0.2 2.1 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain RIP PF00161.14 GAP91062.1 - 2e-34 118.5 0.0 2.8e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 Ribosome inactivating protein Pyr_redox PF00070.22 GAP91063.1 - 5.2e-10 39.5 0.1 1.3e-09 38.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAP91063.1 - 9.3e-08 32.1 0.1 2.5e-06 27.5 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP91063.1 - 0.0003 20.9 0.1 0.0004 20.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAP91063.1 - 0.00049 19.1 0.0 0.00068 18.6 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 GAP91063.1 - 0.00069 18.5 0.1 0.34 9.7 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 GAP91063.1 - 0.0032 16.4 2.2 0.75 8.6 0.0 2.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 GAP91063.1 - 0.014 14.4 0.4 0.23 10.4 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 GAP91063.1 - 0.014 14.3 0.3 0.029 13.2 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.9 GAP91063.1 - 0.025 13.2 0.1 1.2 7.7 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_7 PF13241.1 GAP91063.1 - 0.045 14.0 0.1 0.82 9.9 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 GAP91063.1 - 0.086 12.6 0.8 0.59 9.8 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Ribosomal_60s PF00428.14 GAP91065.1 - 0.00032 21.0 3.8 0.00049 20.4 2.7 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein Prothymosin PF03247.9 GAP91065.1 - 0.29 11.2 11.2 0.38 10.9 7.8 1.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family Acetyltransf_8 PF13523.1 GAP91066.1 - 2.5e-40 137.8 0.3 3.7e-40 137.2 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAP91066.1 - 0.018 15.2 0.1 0.031 14.4 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AMP-binding PF00501.23 GAP91068.1 - 9.1e-100 333.9 0.0 1.3e-99 333.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAP91068.1 - 6.2e-13 49.5 0.7 2.7e-12 47.4 0.5 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 GAP91069.1 - 5.7e-31 107.5 51.6 3.8e-29 101.5 34.4 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily ABC_membrane PF00664.18 GAP91070.1 - 6.1e-73 245.6 29.0 2e-40 138.9 1.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAP91070.1 - 6.1e-62 207.9 0.0 1.7e-29 102.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 GAP91070.1 - 1.8e-16 60.0 0.0 3.7e-06 26.3 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAP91070.1 - 6.4e-10 39.4 0.6 0.0096 15.9 0.0 4.3 4 0 0 4 4 4 2 AAA domain AAA_17 PF13207.1 GAP91070.1 - 6.8e-09 36.5 0.0 0.0044 17.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAP91070.1 - 7e-09 35.0 0.2 0.0028 17.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 GAP91070.1 - 6.2e-07 29.6 0.7 0.14 12.3 0.1 4.1 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 GAP91070.1 - 6.7e-07 28.6 0.0 0.0023 17.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 GAP91070.1 - 1.3e-06 28.5 4.8 0.022 14.7 0.2 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 GAP91070.1 - 3.1e-06 26.7 0.1 0.034 13.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 GAP91070.1 - 5e-06 26.3 0.5 0.16 11.9 0.0 3.5 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 GAP91070.1 - 6e-06 26.7 0.1 0.11 12.7 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 GAP91070.1 - 8.3e-06 26.1 0.0 0.14 12.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain APS_kinase PF01583.15 GAP91070.1 - 1.2e-05 24.9 0.1 0.0035 16.9 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_30 PF13604.1 GAP91070.1 - 3.8e-05 23.3 0.1 0.47 10.0 0.0 3.8 4 0 0 4 4 4 1 AAA domain ABC_ATPase PF09818.4 GAP91070.1 - 0.00011 20.9 0.2 0.0018 16.9 0.0 2.9 4 0 0 4 4 4 1 Predicted ATPase of the ABC class AAA_33 PF13671.1 GAP91070.1 - 0.00039 20.3 0.0 0.85 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 GAP91070.1 - 0.0029 17.4 0.1 0.68 9.7 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 GAP91070.1 - 0.0036 17.2 0.5 1.7 8.5 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase SRP54 PF00448.17 GAP91070.1 - 0.0038 16.6 0.3 4.3 6.7 0.0 3.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_10 PF12846.2 GAP91070.1 - 0.0053 16.2 0.9 1.5 8.1 0.1 2.6 3 0 0 3 3 2 1 AAA-like domain AAA_5 PF07728.9 GAP91070.1 - 0.0067 16.1 0.0 4.1 7.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) DUF3987 PF13148.1 GAP91070.1 - 0.0092 14.5 0.0 1.4 7.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) Zeta_toxin PF06414.7 GAP91070.1 - 0.0095 15.0 0.1 1.2 8.2 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA PF00004.24 GAP91070.1 - 0.027 14.6 0.1 15 5.7 0.0 3.9 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 GAP91070.1 - 0.037 13.7 0.2 12 5.6 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 GAP91070.1 - 0.12 11.8 0.0 6.1 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 GAP91070.1 - 0.19 11.6 0.1 6.1 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 GAP91070.1 - 0.8 8.6 0.0 1.9 7.4 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain ADH_N PF08240.7 GAP91071.1 - 3.3e-30 104.0 0.1 5.1e-30 103.4 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAP91071.1 - 7.4e-27 93.4 0.0 1.1e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAP91071.1 - 0.0011 19.8 0.0 0.0019 19.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ank_2 PF12796.2 GAP91072.1 - 1.6e-19 69.9 0.1 2.5e-08 34.1 0.0 4.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAP91072.1 - 1.4e-16 60.5 2.8 3.2e-06 27.5 0.0 5.9 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP91072.1 - 2.3e-16 59.4 0.7 0.00017 21.7 0.0 4.9 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 GAP91072.1 - 1.3e-15 56.3 0.8 7.7e-05 22.3 0.0 5.6 5 1 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 GAP91072.1 - 4e-11 42.0 0.1 0.062 13.5 0.0 6.4 6 0 0 6 6 6 2 Ankyrin repeat CorA PF01544.13 GAP91072.1 - 2.3e-06 26.8 3.7 2.3e-06 26.8 2.6 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein ACC_central PF08326.7 GAP91075.1 - 4.3e-253 841.6 0.0 5.5e-253 841.2 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 GAP91075.1 - 1.7e-176 587.3 0.1 3.6e-176 586.3 0.0 1.6 2 0 0 2 2 2 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 GAP91075.1 - 1.1e-51 175.1 0.0 2.1e-51 174.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 GAP91075.1 - 8.3e-24 83.8 0.1 2.1e-23 82.5 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 GAP91075.1 - 1.8e-21 76.1 0.0 8.6e-20 70.7 0.0 2.8 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 GAP91075.1 - 4.6e-17 61.4 0.5 1.6e-16 59.6 0.3 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 GAP91075.1 - 2.3e-10 40.5 0.0 5.7e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 GAP91075.1 - 3.1e-06 26.1 0.0 0.017 13.8 0.0 3.1 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 GAP91075.1 - 0.0032 16.9 0.0 0.0066 15.8 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 GAP91075.1 - 0.0061 16.2 0.0 0.037 13.6 0.0 2.3 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_2 PF12700.2 GAP91075.1 - 0.033 13.3 0.0 0.2 10.7 0.0 2.0 2 0 0 2 2 2 0 HlyD family secretion protein ATP-grasp_3 PF02655.9 GAP91075.1 - 0.064 13.1 0.0 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain IPK PF03770.11 GAP91075.1 - 0.22 11.1 0.1 0.44 10.1 0.0 1.4 1 0 0 1 1 1 0 Inositol polyphosphate kinase NUDE_C PF04880.8 GAP91076.1 - 4.8e-19 69.3 6.5 4.8e-19 69.3 4.5 3.3 1 1 2 3 3 1 1 NUDE protein, C-terminal conserved region WEMBL PF05701.6 GAP91076.1 - 0.00031 19.3 29.5 0.00051 18.6 20.5 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light IncA PF04156.9 GAP91076.1 - 0.018 14.6 30.9 0.24 10.9 6.4 2.7 2 1 1 3 3 3 0 IncA protein Filament PF00038.16 GAP91076.1 - 0.03 13.7 27.7 0.082 12.3 18.7 1.9 2 0 0 2 2 2 0 Intermediate filament protein Myosin_tail_1 PF01576.14 GAP91076.1 - 0.11 10.2 32.9 0.2 9.3 14.4 2.2 1 1 1 2 2 2 0 Myosin tail Tropomyosin_1 PF12718.2 GAP91076.1 - 0.2 11.5 35.8 1.2 8.9 14.9 3.9 2 1 1 3 3 3 0 Tropomyosin like Flg_hook PF02120.11 GAP91076.1 - 0.69 9.6 4.9 2.8 7.6 0.3 2.7 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK DUF904 PF06005.7 GAP91076.1 - 0.84 9.9 29.1 0.026 14.7 4.7 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF904) TPR_MLP1_2 PF07926.7 GAP91076.1 - 1.1 8.9 34.6 0.78 9.4 4.7 3.8 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein ERM PF00769.14 GAP91076.1 - 2.7 7.4 31.9 2.9 7.3 8.0 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family AAA_13 PF13166.1 GAP91076.1 - 3.1 6.1 21.1 5 5.4 14.6 1.2 1 0 0 1 1 1 0 AAA domain ADIP PF11559.3 GAP91076.1 - 4.8 7.0 27.3 0.26 11.1 5.5 3.8 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding FliD_N PF02465.13 GAP91076.1 - 5.1 7.5 7.4 3.3 8.1 0.6 3.3 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus RTBV_P46 PF06216.6 GAP91076.1 - 6.2 5.5 10.4 2.6 6.7 1.1 2.3 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein APG6 PF04111.7 GAP91076.1 - 6.6 5.6 31.5 3.9 6.4 12.8 2.8 1 1 2 3 3 3 0 Autophagy protein Apg6 FlxA PF14282.1 GAP91076.1 - 9.3 6.2 14.0 3.1 7.7 2.4 3.5 3 0 0 3 3 3 0 FlxA-like protein Tropomyosin PF00261.15 GAP91076.1 - 9.5 5.2 37.8 42 3.1 24.2 3.0 2 1 0 2 2 2 0 Tropomyosin DUF3669 PF12417.3 GAP91077.1 - 2e-19 69.0 0.1 3.3e-19 68.3 0.1 1.3 1 0 0 1 1 1 1 Zinc finger protein Velvet PF11754.3 GAP91078.1 - 2.5e-07 30.5 0.0 2.9e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Velvet factor CelD_N PF02927.9 GAP91078.1 - 0.0077 16.4 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 N-terminal ig-like domain of cellulase BolA PF01722.13 GAP91079.1 - 8.3e-17 60.9 0.0 2.3e-16 59.4 0.0 1.8 3 0 0 3 3 3 1 BolA-like protein Peptidase_S8 PF00082.17 GAP91080.1 - 4.3e-44 150.7 0.0 9.1e-44 149.7 0.0 1.6 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 GAP91080.1 - 5.2e-17 62.2 0.1 1.1e-16 61.2 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 GAP91080.1 - 8.7e-14 51.0 0.4 1.9e-12 46.7 0.0 2.6 2 0 0 2 2 2 1 PA domain FlgD_ig PF13860.1 GAP91080.1 - 0.01 15.5 0.0 0.029 14.1 0.0 1.7 1 0 0 1 1 1 0 FlgD Ig-like domain COesterase PF00135.23 GAP91081.1 - 3.5e-67 227.3 0.0 5.2e-67 226.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family SnoaL PF07366.7 GAP91081.1 - 1e-23 83.2 0.1 7.4e-23 80.5 0.0 2.1 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 GAP91081.1 - 1.9e-09 37.8 0.7 6.1e-07 29.7 0.1 2.8 2 0 0 2 2 2 2 SnoaL-like domain Abhydrolase_3 PF07859.8 GAP91081.1 - 2e-06 27.5 0.5 4.8e-06 26.2 0.3 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP91081.1 - 0.084 12.6 0.2 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family SSP160 PF06933.6 GAP91081.1 - 1.8 6.4 7.4 2.8 5.7 5.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FAD_binding_4 PF01565.18 GAP91082.1 - 1.3e-29 102.4 0.7 1.9e-29 101.8 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP91082.1 - 9.4e-12 44.6 0.0 2.5e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like TPP_enzyme_N PF02776.13 GAP91083.1 - 5.6e-41 139.8 0.0 3.5e-39 134.0 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 GAP91083.1 - 2.6e-22 79.0 0.0 7e-22 77.6 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 GAP91083.1 - 6.9e-18 64.7 0.0 2.6e-17 62.8 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain UDPGT PF00201.13 GAP91083.1 - 0.045 12.2 0.0 0.072 11.6 0.0 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Cyclin PF08613.6 GAP91084.1 - 2.7e-39 134.9 0.0 4.1e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin Peptidase_M24 PF00557.19 GAP91085.1 - 1.2e-57 194.8 0.0 1.7e-57 194.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 GAP91085.1 - 3.8e-24 84.5 0.0 7.4e-24 83.6 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_S10 PF00450.17 GAP91086.1 - 6.9e-88 295.5 0.0 8.4e-88 295.3 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase CBM_21 PF03370.8 GAP91088.1 - 1.6e-33 115.0 0.7 2.6e-33 114.3 0.1 1.6 2 0 0 2 2 2 1 Putative phosphatase regulatory subunit Phosphoesterase PF04185.9 GAP91089.1 - 4.4e-34 118.3 4.0 6e-34 117.8 2.8 1.2 1 0 0 1 1 1 1 Phosphoesterase family VIT1 PF01988.14 GAP91090.1 - 2e-34 118.9 0.2 5.8e-34 117.4 0.1 1.7 1 1 0 1 1 1 1 VIT family RXT2_N PF08595.6 GAP91090.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal HeLo PF14479.1 GAP91092.1 - 1.5e-06 28.1 0.2 0.012 15.3 0.0 2.6 1 1 1 2 2 2 2 Prion-inhibition and propagation DUF2080 PF09853.4 GAP91094.1 - 0.064 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative transposon-encoded protein (DUF2080) DUF508 PF04370.7 GAP91094.1 - 1.4 8.5 5.4 2.6 7.6 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Ferric_reduct PF01794.14 GAP91095.1 - 1.4e-15 57.4 11.4 1.4e-15 57.4 7.9 2.6 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 GAP91095.1 - 4.2e-14 52.2 0.0 9.8e-14 51.1 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 GAP91095.1 - 9.7e-12 45.0 0.0 1.6e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF4405 PF14358.1 GAP91095.1 - 0.18 11.9 11.6 0.2 11.7 1.4 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) tRNA-synt_1d PF00750.14 GAP91096.1 - 5.6e-83 278.6 5.9 2.4e-82 276.6 4.1 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 GAP91096.1 - 2.2e-28 98.5 0.1 5e-28 97.4 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 GAP91096.1 - 0.04 14.4 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain eIF-5_eIF-2B PF01873.12 GAP91096.1 - 0.087 12.4 0.0 0.46 10.1 0.0 2.0 2 0 0 2 2 2 0 Domain found in IF2B/IF5 p450 PF00067.17 GAP91097.1 - 1.8e-21 76.2 0.0 3.7e-15 55.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 AMP-binding PF00501.23 GAP91098.1 - 0 1061.8 0.0 1.5e-82 277.1 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 GAP91098.1 - 4.8e-190 629.8 3.0 1.2e-57 195.1 0.1 5.2 5 0 0 5 5 5 4 Condensation domain PP-binding PF00550.20 GAP91098.1 - 6.3e-55 183.3 0.7 6.6e-13 48.7 0.0 5.0 4 0 0 4 4 4 4 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 GAP91098.1 - 4.3e-45 151.9 0.4 6.1e-23 80.9 0.0 4.1 4 0 0 4 4 4 2 HxxPF-repeated domain AMP-binding_C PF13193.1 GAP91098.1 - 2.5e-31 108.4 0.3 1.8e-06 28.8 0.0 5.9 5 0 0 5 5 5 5 AMP-binding enzyme C-terminal domain Methyltransf_31 PF13847.1 GAP91098.1 - 0.00051 19.6 0.0 0.0062 16.1 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP91098.1 - 0.0022 18.5 0.0 0.0076 16.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP91098.1 - 0.0055 16.4 0.0 0.046 13.4 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP91098.1 - 0.057 13.4 0.0 0.23 11.5 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain Mt_ATP-synt_D PF05873.7 GAP91098.1 - 0.28 10.8 0.1 0.83 9.2 0.0 1.8 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) FSH1 PF03959.8 GAP91100.1 - 1.9e-24 86.3 0.0 2.7e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 GAP91100.1 - 0.007 16.2 0.0 0.049 13.5 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family ketoacyl-synt PF00109.21 GAP91101.1 - 4.4e-68 229.4 0.0 7.4e-68 228.7 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 GAP91101.1 - 1.8e-61 206.9 0.0 4.9e-61 205.5 0.0 1.8 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 GAP91101.1 - 4.2e-51 174.1 0.0 3.1e-50 171.3 0.0 2.0 1 1 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 GAP91101.1 - 2.6e-46 157.6 1.7 9e-46 155.8 0.0 2.7 3 0 0 3 3 2 1 short chain dehydrogenase PS-DH PF14765.1 GAP91101.1 - 2.2e-43 148.5 0.0 4.3e-43 147.5 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 GAP91101.1 - 4.2e-39 133.0 0.0 2e-38 130.9 0.0 2.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 GAP91101.1 - 7.4e-18 64.3 0.1 2.8e-17 62.4 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAP91101.1 - 2.2e-10 41.4 0.0 3.8e-09 37.5 0.0 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.20 GAP91101.1 - 2.7e-09 37.1 0.1 1e-08 35.3 0.0 2.1 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 GAP91101.1 - 8.9e-09 35.7 0.0 2.8e-08 34.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP91101.1 - 1.2e-06 28.3 0.0 2.6e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP91101.1 - 2.7e-06 27.7 0.0 1.2e-05 25.6 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP91101.1 - 9e-05 22.1 0.0 0.00026 20.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 GAP91101.1 - 0.0006 18.8 0.4 0.0019 17.2 0.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain ADH_N PF08240.7 GAP91101.1 - 0.0024 17.6 0.0 0.0049 16.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 GAP91101.1 - 0.0047 17.5 0.0 0.031 14.8 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP91101.1 - 0.016 15.5 0.0 0.13 12.6 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain DUF915 PF06028.6 GAP91101.1 - 0.073 12.1 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) AlaDh_PNT_C PF01262.16 GAP91101.1 - 0.11 12.0 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lyase_aromatic PF00221.14 GAP91102.1 - 5.9e-158 526.1 1.0 7.2e-158 525.9 0.7 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Trp_DMAT PF11991.3 GAP91102.1 - 1.3e-88 297.6 0.0 1.9e-88 297.1 0.0 1.2 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase p450 PF00067.17 GAP91103.1 - 4e-53 180.5 0.0 5.2e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 GAP91104.1 - 3.4e-22 79.4 10.3 7.3e-22 78.3 7.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP91104.1 - 1.5e-06 28.0 0.0 3.8e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP91104.1 - 0.0084 15.6 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 GAP91104.1 - 0.23 9.9 0.0 0.34 9.3 0.0 1.1 1 0 0 1 1 1 0 Ndr family p450 PF00067.17 GAP91105.1 - 1.1e-41 142.8 0.0 3.8e-27 94.9 0.0 2.8 2 1 0 2 2 2 2 Cytochrome P450 PXA PF02194.10 GAP91106.1 - 1.4e-43 148.6 1.1 2.2e-43 147.9 0.8 1.3 1 0 0 1 1 1 1 PXA domain HTH_Tnp_Tc5 PF03221.11 GAP91107.1 - 2.8e-10 39.8 0.0 6.2e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 GAP91107.1 - 8.1e-07 28.3 0.0 1.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.1 GAP91107.1 - 0.0035 16.9 0.0 0.008 15.8 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_4 PF13613.1 GAP91107.1 - 0.023 14.2 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MarR PF01047.17 GAP91107.1 - 0.025 14.2 0.0 0.06 13.0 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_38 PF13936.1 GAP91107.1 - 0.048 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.2 GAP91107.1 - 0.063 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.1 GAP91107.1 - 0.15 11.4 0.0 0.34 10.3 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TGS PF02824.16 GAP91108.1 - 2.5e-22 78.4 0.1 5e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 GAP91108.1 - 6.3e-18 64.8 0.0 1.7e-17 63.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAP91108.1 - 1.8e-09 37.0 0.1 9.3e-09 34.7 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 GAP91108.1 - 0.00013 21.8 0.2 0.027 14.2 0.0 2.4 1 1 1 2 2 2 1 Dynamin family GTP_EFTU PF00009.22 GAP91108.1 - 0.00021 20.7 0.3 1.5 8.2 0.0 3.7 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 GAP91108.1 - 0.0048 15.7 0.5 0.014 14.2 0.1 1.9 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 GAP91108.1 - 0.011 16.2 0.0 0.16 12.5 0.0 2.5 1 1 0 2 2 2 0 Miro-like protein Arf PF00025.16 GAP91108.1 - 0.015 14.5 0.1 2.5 7.3 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AIG1 PF04548.11 GAP91108.1 - 0.056 12.5 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 AIG1 family CBS PF00571.23 GAP91108.1 - 0.058 13.2 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 CBS domain DUF2922 PF11148.3 GAP91108.1 - 0.12 12.0 0.3 0.4 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2922) Steroid_dh PF02544.11 GAP91109.1 - 9.5e-15 54.6 3.8 9.5e-15 54.6 2.6 1.6 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 GAP91109.1 - 0.053 12.8 3.0 0.2 10.8 2.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) Ank_2 PF12796.2 GAP91110.1 - 1.7e-27 95.5 0.5 2e-18 66.4 0.2 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAP91110.1 - 2.3e-19 68.1 5.0 1.8e-08 33.7 0.1 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 GAP91110.1 - 9.7e-16 57.4 3.5 8.7e-08 32.1 0.1 5.4 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAP91110.1 - 2.3e-15 56.6 0.1 1e-08 35.4 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP91110.1 - 4.7e-15 54.1 0.7 7.5e-05 22.6 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat SKG6 PF08693.5 GAP91111.1 - 1.5e-06 27.3 0.2 1.5e-06 27.3 0.1 1.7 2 0 0 2 2 2 1 Transmembrane alpha-helix domain CFEM PF05730.6 GAP91111.1 - 0.011 15.4 0.3 0.018 14.8 0.2 1.3 1 0 0 1 1 1 0 CFEM domain Mucin PF01456.12 GAP91111.1 - 0.39 10.4 15.2 0.72 9.6 10.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Mito_fiss_reg PF05308.6 GAP91112.1 - 0.12 11.7 0.2 0.12 11.7 0.1 1.6 2 0 0 2 2 2 0 Mitochondrial fission regulator ADK PF00406.17 GAP91113.1 - 4.6e-08 33.0 0.0 3.7e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.1 GAP91113.1 - 5.6e-08 33.6 0.1 3.8e-07 30.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAP91113.1 - 1.5e-06 28.5 0.1 1.4e-05 25.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAP91113.1 - 6.1e-06 26.1 0.7 6e-05 22.9 0.5 2.2 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 GAP91113.1 - 0.004 17.1 0.6 0.064 13.2 0.4 2.4 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 GAP91113.1 - 0.011 15.5 0.2 3.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase PGAP1 PF07819.8 GAP91113.1 - 0.014 15.0 0.0 0.017 14.7 0.0 1.1 1 0 0 1 1 1 0 PGAP1-like protein SR-25 PF10500.4 GAP91115.1 - 0.034 13.6 3.0 0.04 13.3 2.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Activator_LAG-3 PF11498.3 GAP91115.1 - 0.071 11.8 18.0 0.081 11.6 12.5 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 FimP PF09766.4 GAP91115.1 - 0.096 11.7 4.5 0.12 11.4 3.1 1.0 1 0 0 1 1 1 0 Fms-interacting protein Prp31_C PF09785.4 GAP91115.1 - 0.42 11.0 10.1 0.76 10.2 7.0 1.4 1 1 0 1 1 1 0 Prp31 C terminal domain PAT1 PF09770.4 GAP91115.1 - 0.49 8.5 14.7 0.52 8.4 10.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Rubella_Capsid PF05750.6 GAP91115.1 - 0.54 9.6 6.2 0.54 9.6 4.3 1.0 1 0 0 1 1 1 0 Rubella capsid protein DUF4106 PF13388.1 GAP91115.1 - 0.96 8.3 10.2 1.1 8.0 7.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Phage_Gp23 PF10669.4 GAP91115.1 - 2.3 8.3 6.4 2.8 8.0 4.4 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) RIC3 PF15361.1 GAP91115.1 - 2.4 8.3 10.2 3.5 7.8 7.1 1.3 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 ATG22 PF11700.3 GAP91117.1 - 6.3e-51 173.3 6.6 7.2e-51 173.1 4.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like WSC PF01822.14 GAP91118.1 - 7.7e-33 112.2 27.2 1.1e-17 63.7 6.0 5.4 6 0 0 6 6 6 2 WSC domain NFRKB_winged PF14465.1 GAP91118.1 - 0.083 12.7 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 NFRKB Winged Helix-like Mucin PF01456.12 GAP91118.1 - 0.69 9.6 59.7 0.69 9.6 20.2 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein CFEM PF05730.6 GAP91119.1 - 3.1e-07 30.1 6.3 5.1e-07 29.4 4.3 1.3 1 0 0 1 1 1 1 CFEM domain SKG6 PF08693.5 GAP91119.1 - 0.11 11.7 0.8 0.23 10.8 0.5 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain p450 PF00067.17 GAP91120.1 - 2.6e-56 191.1 0.0 3.3e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Prismane PF03063.15 GAP91121.1 - 0.078 11.3 0.7 0.11 10.8 0.5 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family UbiA PF01040.13 GAP91122.1 - 2.1e-23 82.8 18.5 3.1e-23 82.3 12.8 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family EthD PF07110.6 GAP91123.1 - 1.4e-22 80.4 1.8 1.6e-22 80.2 1.2 1.1 1 0 0 1 1 1 1 EthD domain PCI PF01399.22 GAP91124.1 - 5.2e-08 33.1 0.6 1.5e-06 28.4 0.0 2.8 2 0 0 2 2 2 1 PCI domain CAF-1_p150 PF11600.3 GAP91124.1 - 5.8e-05 22.5 22.2 5.8e-05 22.5 15.4 3.4 2 1 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal G-gamma PF00631.17 GAP91125.1 - 3.7e-26 90.6 0.0 5.2e-26 90.1 0.0 1.2 1 0 0 1 1 1 1 GGL domain Rdx PF10262.4 GAP91126.1 - 6.1e-28 96.6 0.0 9.6e-28 96.0 0.0 1.3 1 0 0 1 1 1 1 Rdx family Metallophos PF00149.23 GAP91127.1 - 2.1e-44 151.3 0.2 2.7e-44 150.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-HC5HC2H_2 PF13832.1 GAP91128.1 - 8.4e-33 112.6 7.7 8.4e-33 112.6 5.3 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 GAP91128.1 - 1.2e-25 89.4 7.1 1.2e-25 89.4 4.9 2.7 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 GAP91128.1 - 1e-18 68.0 0.1 4e-18 66.1 0.1 2.1 1 1 0 1 1 1 1 Enhancer of polycomb-like PHD_2 PF13831.1 GAP91128.1 - 2.9e-14 52.0 2.1 2.9e-14 52.0 1.4 2.0 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 GAP91128.1 - 1.6e-08 34.0 25.1 8.7e-08 31.7 6.7 2.7 2 0 0 2 2 2 2 PHD-finger LRR_4 PF12799.2 GAP91129.1 - 2.4e-15 55.7 5.9 9.2e-05 21.9 2.1 4.7 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAP91129.1 - 1.2e-12 47.3 4.2 1.4e-07 31.1 2.1 2.9 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 GAP91129.1 - 7.2e-09 34.4 8.9 2.4 8.5 0.2 6.6 5 1 1 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 GAP91129.1 - 0.015 15.3 11.9 25 5.6 0.2 6.2 6 0 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 GAP91129.1 - 0.017 15.1 5.0 46 4.5 0.0 5.3 5 0 0 5 5 5 0 Leucine Rich repeat Mac PF12464.3 GAP91131.1 - 4.2e-20 71.5 0.0 6.1e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 GAP91131.1 - 1.2e-13 49.8 13.4 5e-12 44.7 3.7 3.7 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 GAP91131.1 - 2.6e-12 46.0 3.7 2.6e-12 46.0 2.6 3.2 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Subtilosin_A PF11420.3 GAP91131.1 - 0.088 12.8 0.6 0.088 12.8 0.4 2.2 3 0 0 3 3 3 0 Bacteriocin subtilosin A Biotin_lipoyl PF00364.17 GAP91133.1 - 4.5e-20 71.0 1.6 5.7e-20 70.7 0.4 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 GAP91133.1 - 2.9e-08 33.2 0.0 8.1e-08 31.7 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 GAP91133.1 - 4.6e-05 22.9 0.0 0.00015 21.3 0.0 1.8 2 0 0 2 2 2 1 Biotin-lipoyl like CoA_transf_3 PF02515.12 GAP91136.1 - 1.6e-25 89.4 0.1 5e-25 87.8 0.0 1.8 3 0 0 3 3 3 1 CoA-transferase family III Fungal_trans PF04082.13 GAP91137.1 - 2.6e-25 88.8 0.5 6.1e-25 87.5 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP91137.1 - 4.3e-08 32.9 12.3 8.6e-08 31.9 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M10 PF00413.19 GAP91137.1 - 0.1 12.2 0.1 0.23 11.1 0.1 1.5 1 0 0 1 1 1 0 Matrixin Fungal_trans PF04082.13 GAP91138.1 - 4.5e-13 48.6 0.0 9.6e-13 47.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain GST_N_3 PF13417.1 GAP91139.1 - 4.5e-14 52.4 0.0 7.6e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAP91139.1 - 8.8e-12 44.8 0.1 3.9e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAP91139.1 - 1.5e-09 37.8 0.0 3.8e-09 36.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAP91139.1 - 1.7e-09 37.5 0.0 2.7e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAP91139.1 - 3.9e-05 23.4 0.3 0.00011 21.9 0.2 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAP91139.1 - 0.013 15.9 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SPT6_acidic PF14632.1 GAP91140.1 - 0.11 12.6 1.8 0.18 12.0 1.3 1.3 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Glyco_hydro_16 PF00722.16 GAP91141.1 - 1.6e-10 40.5 5.8 2.5e-10 39.9 4.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 NDUF_B8 PF05821.6 GAP91141.1 - 0.017 14.7 0.5 0.038 13.6 0.4 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) WW PF00397.21 GAP91142.1 - 0.00017 21.4 2.0 0.00043 20.0 1.4 1.8 1 0 0 1 1 1 1 WW domain RIX1 PF08167.7 GAP91143.1 - 1.9e-45 154.4 0.2 3.6e-45 153.6 0.1 1.5 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis TPR_2 PF07719.12 GAP91144.1 - 9.6e-13 47.0 2.1 0.11 12.4 0.1 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 GAP91144.1 - 8.3e-11 41.5 11.2 0.11 13.1 0.1 8.4 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAP91144.1 - 3.1e-07 29.6 3.1 0.0013 18.3 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAP91144.1 - 4e-07 29.5 1.8 1.1 9.0 0.1 5.6 5 0 0 5 5 5 2 TPR repeat TPR_17 PF13431.1 GAP91144.1 - 1.3e-06 28.1 1.8 0.037 14.2 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAP91144.1 - 8.9e-06 25.1 2.5 0.91 9.2 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAP91144.1 - 0.00011 22.4 6.1 0.05 13.9 0.0 5.4 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAP91144.1 - 0.00021 20.8 4.1 0.89 9.5 0.1 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAP91144.1 - 0.0021 17.9 6.1 16 5.5 0.0 6.5 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAP91144.1 - 0.0046 17.5 15.5 2.3 8.9 0.6 6.9 6 1 2 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAP91144.1 - 0.078 13.4 4.6 0.41 11.2 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Methyltransf_PK PF05891.7 GAP91146.1 - 6.1e-77 257.8 0.0 7.1e-77 257.5 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase SGL PF08450.7 GAP91147.1 - 4.1e-44 150.7 0.0 4.3e-43 147.4 0.0 2.4 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region PQQ_2 PF13360.1 GAP91147.1 - 0.018 14.5 0.1 0.58 9.5 0.0 2.5 2 1 1 3 3 3 0 PQQ-like domain bZIP_2 PF07716.10 GAP91148.1 - 0.00098 18.9 12.8 0.0019 17.9 8.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 GAP91148.1 - 0.09 12.7 14.2 0.4 10.6 9.8 1.9 1 1 0 1 1 1 0 bZIP transcription factor HOOK PF05622.7 GAP91148.1 - 0.15 9.8 4.3 0.19 9.4 3.0 1.1 1 0 0 1 1 1 0 HOOK protein DivIC PF04977.10 GAP91148.1 - 1.6 8.3 4.0 0.76 9.3 1.1 1.6 1 1 1 2 2 2 0 Septum formation initiator Sugar_tr PF00083.19 GAP91149.1 - 1.2e-96 324.1 26.1 1.4e-96 323.8 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP91149.1 - 5e-25 87.9 31.5 2.9e-19 68.9 6.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily IlvC PF01450.14 GAP91149.1 - 0.095 12.6 0.1 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain OATP PF03137.15 GAP91149.1 - 0.29 9.1 10.2 0.07 11.1 2.3 2.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Pectate_lyase_3 PF12708.2 GAP91150.1 - 4.8e-35 121.7 14.1 1.8e-24 87.1 5.1 2.6 2 0 0 2 2 2 2 Pectate lyase superfamily protein Beta_helix PF13229.1 GAP91150.1 - 0.071 12.8 14.3 0.31 10.7 9.9 2.1 1 1 0 1 1 1 0 Right handed beta helix region ERG4_ERG24 PF01222.12 GAP91151.1 - 3.1e-155 516.9 9.0 3.5e-155 516.7 6.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 GAP91151.1 - 1.7e-05 24.2 0.6 0.00018 20.9 0.1 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) ADH_N PF08240.7 GAP91152.1 - 2.6e-09 36.8 0.0 4e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAP91152.1 - 6.2e-09 35.4 0.0 1.2e-08 34.5 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DUF2040 PF09745.4 GAP91154.1 - 9.5e-36 122.4 14.0 9.5e-36 122.4 9.7 3.1 2 1 1 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) DUF2315 PF10231.4 GAP91154.1 - 6.5 6.6 6.9 0.79 9.6 0.6 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2315) Macoilin PF09726.4 GAP91155.1 - 0.65 8.2 9.1 0.7 8.0 6.3 1.1 1 0 0 1 1 1 0 Transmembrane protein MIP-T3 PF10243.4 GAP91155.1 - 1 7.7 20.0 1.3 7.4 13.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Neurochondrin PF05536.6 GAP91157.1 - 2.1e-50 171.5 0.0 3.2e-50 170.9 0.0 1.2 1 0 0 1 1 1 1 Neurochondrin Voltage_CLC PF00654.15 GAP91158.1 - 8e-88 294.8 30.2 8e-88 294.8 20.9 1.8 3 0 0 3 3 3 1 Voltage gated chloride channel DUF1301 PF06979.7 GAP91158.1 - 1.6 8.9 3.5 23 5.1 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1301) zf-C3HC4_3 PF13920.1 GAP91159.1 - 3.9e-11 42.4 8.4 6.1e-11 41.8 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAP91159.1 - 8e-10 38.3 12.0 1.9e-09 37.2 8.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAP91159.1 - 4.7e-08 32.9 10.9 8.6e-08 32.0 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAP91159.1 - 1.5e-06 27.8 10.4 3e-06 26.8 7.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 GAP91159.1 - 4e-06 26.3 11.1 6.8e-06 25.6 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAP91159.1 - 0.0018 18.1 4.2 0.0018 18.1 2.9 1.7 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TerY-C PF15616.1 GAP91159.1 - 0.0018 18.1 1.7 0.0039 17.1 1.2 1.5 1 0 0 1 1 1 1 TerY-C metal binding domain zf-RING_4 PF14570.1 GAP91159.1 - 0.0033 16.9 4.9 0.0061 16.1 3.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 GAP91159.1 - 0.0055 16.3 4.7 0.0055 16.3 3.2 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 GAP91159.1 - 0.02 14.7 8.9 0.038 13.8 6.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PolC_DP2 PF03833.8 GAP91159.1 - 0.032 11.9 0.3 0.043 11.4 0.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-RING_6 PF14835.1 GAP91159.1 - 0.053 13.3 2.7 0.1 12.3 1.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Macoilin PF09726.4 GAP91159.1 - 0.19 9.9 0.3 0.19 9.9 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein Prok-RING_4 PF14447.1 GAP91159.1 - 7.5 6.1 14.2 0.53 9.8 5.3 2.4 2 1 0 2 2 1 0 Prokaryotic RING finger family 4 Pkinase_Tyr PF07714.12 GAP91160.1 - 6.1e-06 25.4 0.0 0.21 10.6 0.0 3.6 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.20 GAP91160.1 - 2.8e-05 23.4 0.0 0.016 14.3 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain DASH_Duo1 PF08651.5 GAP91161.1 - 1.6 8.3 6.4 0.8 9.3 0.2 3.2 3 1 1 4 4 4 0 DASH complex subunit Duo1 AMP-binding PF00501.23 GAP91162.1 - 6.4e-81 271.8 0.0 9.2e-81 271.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 GAP91162.1 - 6.2e-37 127.0 3.1 1.8e-21 76.2 0.3 2.3 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 GAP91162.1 - 6.5e-09 35.9 0.4 0.00066 19.8 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAP91162.1 - 8.4e-06 26.6 0.0 3.1e-05 24.8 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 GAP91162.1 - 0.00036 20.7 0.0 0.0012 19.1 0.0 1.9 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_11 PF08241.7 GAP91163.1 - 1.2e-05 25.6 0.0 2.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP91163.1 - 0.064 12.3 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Ank_2 PF12796.2 GAP91164.1 - 1.7e-106 348.7 23.9 2.2e-14 53.5 0.1 14.1 4 3 8 13 13 13 13 Ankyrin repeats (3 copies) Ank PF00023.25 GAP91164.1 - 2e-77 251.3 35.9 9.8e-09 34.5 0.3 25.5 26 1 0 26 26 26 18 Ankyrin repeat Ank_4 PF13637.1 GAP91164.1 - 7.3e-76 249.3 27.9 3e-07 30.7 0.0 17.2 12 4 3 16 16 16 12 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP91164.1 - 1.6e-64 212.4 34.9 5.6e-07 29.6 0.0 19.4 9 6 12 21 21 21 16 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP91164.1 - 3e-61 197.2 25.3 0.00017 21.5 0.1 24.3 25 0 0 25 25 25 15 Ankyrin repeat ZZ PF00569.12 GAP91164.1 - 1.5e-11 43.5 5.5 1.7e-10 40.2 4.6 2.1 2 0 0 2 2 2 1 Zinc finger, ZZ type PGAP1 PF07819.8 GAP91164.1 - 0.0016 18.0 0.0 0.0037 16.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 GAP91164.1 - 0.063 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ank_2 PF12796.2 GAP91165.1 - 4.8e-55 183.8 0.2 3.9e-11 43.1 0.0 8.2 3 3 6 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAP91165.1 - 4e-33 113.1 8.4 1.6e-09 38.0 0.1 10.5 8 3 3 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP91165.1 - 9.9e-25 84.1 9.8 0.076 13.2 0.0 12.2 12 0 0 12 12 12 6 Ankyrin repeat Ank PF00023.25 GAP91165.1 - 1.1e-24 84.9 22.1 0.0039 16.9 0.2 11.7 12 0 0 12 12 12 8 Ankyrin repeat Ank_5 PF13857.1 GAP91165.1 - 3.3e-22 77.9 11.3 0.029 14.6 0.0 10.2 7 2 5 12 12 12 8 Ankyrin repeats (many copies) Clr5 PF14420.1 GAP91165.1 - 7.9e-07 28.8 2.7 1.4e-05 24.8 1.5 3.4 4 0 0 4 4 4 1 Clr5 domain FMN_dh PF01070.13 GAP91167.1 - 1e-114 383.1 0.0 1.2e-114 382.9 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 GAP91167.1 - 0.0003 20.0 0.6 0.00045 19.4 0.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 GAP91167.1 - 0.00098 18.1 0.3 0.0018 17.2 0.2 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 GAP91167.1 - 0.0016 17.5 0.7 1.2 8.1 0.0 2.2 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 GAP91167.1 - 0.0025 16.8 0.2 0.0035 16.3 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 GAP91167.1 - 0.016 14.4 0.2 1.4 8.1 0.0 2.2 1 1 1 2 2 2 0 Histidine biosynthesis protein DUF2413 PF10310.4 GAP91169.1 - 0.42 9.3 7.0 0.45 9.2 4.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) MLIP PF15274.1 GAP91169.1 - 0.68 9.3 8.7 0.82 9.1 6.1 1.1 1 0 0 1 1 1 0 Muscular LMNA-interacting protein DUF566 PF04484.7 GAP91169.1 - 8.3 5.8 16.2 9.8 5.5 11.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) MSA-2c PF12238.3 GAP91169.1 - 9.4 5.8 9.9 10 5.6 6.9 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c ABC1 PF03109.11 GAP91170.1 - 2.4e-32 111.4 0.0 3.9e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Pex19 PF04614.7 GAP91172.1 - 3e-69 233.4 16.0 3e-69 233.4 11.1 1.6 2 0 0 2 2 2 1 Pex19 protein family GET2 PF08690.5 GAP91172.1 - 7.3 5.7 12.4 35 3.5 7.8 2.4 1 1 0 1 1 1 0 GET complex subunit GET2 FliE PF02049.13 GAP91172.1 - 7.5 6.6 9.2 1.6 8.7 2.5 2.7 2 1 1 3 3 3 0 Flagellar hook-basal body complex protein FliE UQ_con PF00179.21 GAP91173.1 - 4.5e-47 159.0 0.0 5e-47 158.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAP91173.1 - 0.0064 16.2 0.0 0.011 15.4 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 GAP91173.1 - 0.18 11.6 0.9 0.3 10.9 0.6 1.7 1 1 0 1 1 1 0 RWD domain Asn_synthase PF00733.16 GAP91174.1 - 4.1e-70 236.1 0.0 5.8e-70 235.6 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 GAP91174.1 - 5e-36 123.1 0.0 8.6e-36 122.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 GAP91174.1 - 1.2e-29 102.9 0.0 4.2e-28 97.9 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 GAP91174.1 - 9.5e-06 24.9 0.0 1.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 GAP91174.1 - 0.00086 18.2 0.1 0.0018 17.2 0.1 1.6 1 1 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 GAP91174.1 - 0.00095 17.9 0.0 0.017 13.8 0.0 2.3 1 1 2 3 3 3 1 Glutamine amidotransferases class-II QueC PF06508.8 GAP91174.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC GPI-anchored PF10342.4 GAP91175.1 - 7e-14 52.0 0.0 2e-13 50.6 0.0 1.8 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family WWbp PF10349.4 GAP91175.1 - 1.3 9.8 18.3 0.11 13.4 7.9 2.5 3 0 0 3 3 3 0 WW-domain ligand protein zf-C2H2_4 PF13894.1 GAP91176.1 - 2.1e-07 30.8 19.2 0.027 14.7 0.2 5.7 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.21 GAP91176.1 - 0.017 15.4 21.4 0.16 12.4 1.0 4.6 4 1 0 4 4 4 0 Zinc finger, C2H2 type Glyco_hydro_43 PF04616.9 GAP91177.1 - 7.9e-21 74.3 3.4 1.3e-20 73.6 2.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_31 PF01055.21 GAP91178.1 - 5.2e-164 546.2 0.5 6.5e-164 545.9 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 GAP91178.1 - 9e-12 44.6 0.6 9.6e-11 41.3 0.3 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like RabGAP-TBC PF00566.13 GAP91179.1 - 2.5e-47 161.1 0.0 3.8e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.17 GAP91180.1 - 1.6e-38 130.1 0.5 3.4e-18 65.0 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP91180.1 - 7.7e-29 99.4 0.1 2.8e-13 49.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP91180.1 - 3.8e-11 42.6 2.9 2.7e-05 23.9 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAP91180.1 - 0.0015 18.2 0.1 0.95 9.2 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 GAP91180.1 - 0.052 13.4 0.1 15 5.4 0.0 2.6 2 0 0 2 2 2 0 RNA binding motif Complex1_LYR_2 PF13233.1 GAP91180.1 - 0.61 10.6 4.4 1.4 9.4 3.0 1.6 1 0 0 1 1 1 0 Complex1_LYR-like PhyH PF05721.8 GAP91181.1 - 1.3e-59 201.7 0.0 1.7e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 GAP91181.1 - 0.014 15.6 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase CTP_transf_2 PF01467.21 GAP91182.1 - 7e-16 58.6 0.1 3.4e-15 56.4 0.0 2.2 2 1 0 2 2 2 1 Cytidylyltransferase cNMP_binding PF00027.24 GAP91183.1 - 2.4e-41 139.4 0.0 1.1e-20 73.1 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain GXGXG PF01493.14 GAP91183.1 - 0.0067 15.4 0.0 0.085 11.8 0.0 2.0 2 0 0 2 2 2 1 GXGXG motif BCAS2 PF05700.6 GAP91184.1 - 4.4e-37 127.6 0.0 6.2e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF4407 PF14362.1 GAP91184.1 - 0.045 12.7 0.2 0.082 11.8 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) OpuAC PF04069.7 GAP91184.1 - 0.047 13.0 0.1 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system Ceramidase_alk PF04734.8 GAP91185.1 - 6.7e-274 909.9 0.0 5.1e-273 907.0 0.0 1.9 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase DUF1793 PF08760.6 GAP91186.1 - 1.1e-62 210.8 0.0 2.4e-62 209.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) PT PF04886.7 GAP91188.1 - 3.3e-10 39.0 49.0 4.6e-05 22.6 7.0 6.5 3 3 1 4 4 4 2 PT repeat ATP-synt_C PF00137.16 GAP91189.1 - 1.1e-30 105.3 30.1 8.1e-19 67.2 9.3 2.0 2 0 0 2 2 2 2 ATP synthase subunit C Flavi_NS4A PF01350.12 GAP91189.1 - 0.54 9.7 4.2 0.24 10.9 0.9 1.8 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A Ribosomal_L7Ae PF01248.21 GAP91190.1 - 2e-25 88.1 0.1 2.3e-25 87.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 GAP91190.1 - 0.0023 17.7 0.0 0.0031 17.3 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 Syja_N PF02383.13 GAP91191.1 - 3.4e-92 308.6 0.0 4.6e-92 308.1 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 GAP91191.1 - 5.8e-34 115.9 0.0 9.7e-34 115.2 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase DUF3115 PF11312.3 GAP91192.1 - 1.5e-78 263.8 0.0 8.5e-64 215.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3115) Transketolase_N PF00456.16 GAP91193.1 - 7.2e-151 501.6 0.2 1.2e-150 500.9 0.1 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 GAP91193.1 - 4.1e-44 150.1 0.0 7.3e-44 149.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 GAP91193.1 - 1.4e-11 44.3 0.0 2.7e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 GAP91193.1 - 1.9e-06 27.0 0.2 2.2e-05 23.5 0.1 2.0 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 GAP91193.1 - 0.017 13.8 0.2 0.027 13.1 0.1 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component Nop14 PF04147.7 GAP91194.1 - 1.2 6.9 3.3 1.5 6.6 2.3 1.0 1 0 0 1 1 1 0 Nop14-like family FUSC_2 PF13515.1 GAP91196.1 - 1.9e-26 92.5 5.6 1.9e-26 92.5 3.9 2.8 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 GAP91196.1 - 3.8e-11 42.1 4.2 1e-08 34.1 1.9 2.4 2 0 0 2 2 2 2 Fusaric acid resistance protein family ALMT PF11744.3 GAP91196.1 - 1.6e-07 30.3 13.5 0.00075 18.2 2.8 4.2 4 0 0 4 4 4 3 Aluminium activated malate transporter DUF2422 PF10337.4 GAP91196.1 - 6.7e-05 21.8 0.1 6.7e-05 21.8 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 GAP91196.1 - 0.00021 20.9 0.1 0.00054 19.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) COPIIcoated_ERV PF07970.7 GAP91197.1 - 2.1e-34 119.1 0.0 2.9e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 GAP91197.1 - 3.5e-22 78.1 0.0 5.8e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF3632 PF12311.3 GAP91198.1 - 5.6e-20 71.9 0.0 8.4e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) ZZ PF00569.12 GAP91199.1 - 2.6e-19 68.4 57.5 4.9e-06 25.9 7.6 4.5 4 0 0 4 4 4 4 Zinc finger, ZZ type zf-DHHC PF01529.15 GAP91199.1 - 0.074 12.4 8.6 0.052 12.9 0.5 2.6 2 0 0 2 2 2 0 DHHC palmitoyltransferase Btz PF09405.5 GAP91200.1 - 7.2e-27 93.9 0.3 1.9e-26 92.6 0.2 1.7 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding TFIIF_alpha PF05793.7 GAP91200.1 - 4.9 5.3 6.5 7 4.9 4.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Asp PF00026.18 GAP91201.1 - 1.4e-62 211.8 1.5 1.7e-62 211.5 1.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAP91201.1 - 1.8e-06 28.0 0.0 9e-06 25.7 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 GAP91201.1 - 0.03 14.8 1.1 4.4 7.8 0.0 3.1 3 1 0 3 3 3 0 Aspartyl protease Aminotran_4 PF01063.14 GAP91202.1 - 6.4e-14 51.9 0.0 1.1e-13 51.2 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class IV TPR_11 PF13414.1 GAP91203.1 - 1e-52 175.6 20.2 4.5e-15 55.0 0.4 6.5 5 1 1 6 6 6 6 TPR repeat TPR_1 PF00515.23 GAP91203.1 - 2.4e-41 137.6 21.5 0.00013 21.4 0.0 11.6 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 GAP91203.1 - 5.7e-37 122.6 22.9 0.00018 21.1 0.0 11.6 11 1 1 12 12 11 8 Tetratricopeptide repeat TPR_16 PF13432.1 GAP91203.1 - 2.5e-26 91.7 5.2 1.6e-05 25.4 0.0 6.4 4 2 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 GAP91203.1 - 6.2e-23 80.5 24.6 5.7e-09 35.7 0.0 7.6 3 2 6 9 9 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 GAP91203.1 - 3.3e-21 73.6 11.3 2.1e-05 24.3 0.0 9.8 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_8 PF13181.1 GAP91203.1 - 2.1e-17 61.4 16.0 0.028 14.1 0.0 10.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.1 GAP91203.1 - 4.7e-13 47.8 19.6 0.006 16.2 0.1 9.0 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAP91203.1 - 3.7e-12 45.7 16.2 0.031 14.8 0.3 8.9 3 3 8 11 11 11 4 Tetratricopeptide repeat Apc3 PF12895.2 GAP91203.1 - 3.4e-11 43.1 15.3 0.0013 18.7 0.1 5.6 2 1 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 GAP91203.1 - 4.8e-11 42.8 19.3 7.5e-06 26.1 0.6 6.0 5 2 0 6 6 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 GAP91203.1 - 1.9e-10 40.4 12.7 0.00011 21.9 0.1 6.0 3 1 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 GAP91203.1 - 4e-05 23.8 18.5 3.5 8.3 0.0 8.1 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_10 PF13374.1 GAP91203.1 - 0.00027 20.7 8.4 1.8 8.6 0.4 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat NARP1 PF12569.3 GAP91203.1 - 0.023 13.4 0.2 0.023 13.4 0.1 5.6 3 2 2 6 6 5 0 NMDA receptor-regulated protein 1 TPR_3 PF07720.7 GAP91203.1 - 0.027 14.2 16.4 2.4 8.0 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 GAP91203.1 - 0.033 13.4 11.8 2.9 7.2 0.0 5.5 6 0 0 6 6 5 0 SHNi-TPR Rapsyn_N PF10579.4 GAP91203.1 - 0.043 13.6 2.2 1.8 8.3 0.0 4.0 3 1 1 4 4 4 0 Rapsyn N-terminal myristoylation and linker region TPR_4 PF07721.9 GAP91203.1 - 0.054 13.9 0.3 25 5.6 0.0 3.9 3 0 0 3 3 2 0 Tetratricopeptide repeat MAS20 PF02064.10 GAP91203.1 - 0.22 11.4 9.6 2.2 8.2 0.0 4.3 5 1 0 5 5 5 0 MAS20 protein import receptor TPR_20 PF14561.1 GAP91203.1 - 0.48 10.5 8.8 1.6 8.8 0.1 4.9 5 1 1 6 6 5 0 Tetratricopeptide repeat Sel1 PF08238.7 GAP91203.1 - 0.79 10.4 9.3 2 9.1 0.1 4.1 4 0 0 4 4 3 0 Sel1 repeat Apc5 PF12862.2 GAP91203.1 - 4.2 7.2 13.2 10 6.0 0.1 4.6 4 2 1 5 5 3 0 Anaphase-promoting complex subunit 5 Amidohydro_1 PF01979.15 GAP91204.1 - 2.4e-13 50.4 1.6 1.7e-11 44.3 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 GAP91204.1 - 6.1e-10 39.5 27.1 6.1e-10 39.5 18.8 2.1 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_5 PF13594.1 GAP91204.1 - 1.3e-06 28.0 0.0 4.2e-06 26.4 0.0 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 GAP91204.1 - 1.4e-05 24.5 3.5 2.4e-05 23.7 0.2 2.2 2 0 0 2 2 2 1 Amidohydrolase family AhpC-TSA_2 PF13911.1 GAP91205.1 - 3.4e-16 59.1 0.0 7.2e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 GAP91205.1 - 0.00033 20.3 0.0 0.0006 19.4 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 GAP91205.1 - 0.086 12.3 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 Redoxin SNARE PF05739.14 GAP91206.1 - 2.1e-14 52.9 2.0 2.1e-14 52.9 1.4 2.7 4 0 0 4 4 4 1 SNARE domain Syntaxin PF00804.20 GAP91206.1 - 2.9e-08 33.7 0.8 2.9e-08 33.7 0.5 2.2 2 0 0 2 2 2 1 Syntaxin Sfi1_C PF10638.4 GAP91206.1 - 0.0017 18.7 0.0 0.31 11.4 0.0 2.9 3 0 0 3 3 3 1 Spindle body associated protein C-terminus Allexi_40kDa PF05549.6 GAP91206.1 - 0.0099 15.1 2.4 0.044 13.0 0.1 2.0 2 0 0 2 2 2 1 Allexivirus 40kDa protein DUF3153 PF11353.3 GAP91206.1 - 0.038 13.4 3.7 0.1 12.0 2.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3153) PBP1_TM PF14812.1 GAP91206.1 - 0.042 14.1 2.2 0.07 13.4 0.0 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tmemb_55A PF09788.4 GAP91206.1 - 0.11 11.6 0.3 0.17 11.0 0.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 55A TPR_MLP1_2 PF07926.7 GAP91206.1 - 1.4 8.6 6.7 1.1 9.0 0.2 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.5 GAP91206.1 - 5.6 7.0 6.8 7.5 6.6 0.3 2.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family APH PF01636.18 GAP91207.1 - 2.1e-16 60.3 0.0 3.3e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 GAP91207.1 - 0.0025 16.9 0.0 0.011 14.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Brix PF04427.13 GAP91208.1 - 1.9e-45 154.8 0.2 2.4e-45 154.5 0.1 1.1 1 0 0 1 1 1 1 Brix domain DUF2857 PF11198.3 GAP91208.1 - 0.04 13.4 0.1 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) UPF1_Zn_bind PF09416.5 GAP91209.1 - 3.3e-73 244.2 3.3 9.3e-73 242.8 1.0 2.3 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 GAP91209.1 - 4.7e-59 199.1 0.0 8.5e-59 198.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAP91209.1 - 5.2e-55 186.5 0.5 1e-54 185.6 0.4 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAP91209.1 - 1.8e-14 53.1 0.1 4.7e-14 51.8 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 GAP91209.1 - 7.2e-13 48.5 1.3 3.2e-11 43.1 0.1 3.0 2 1 0 2 2 2 1 AAA domain ResIII PF04851.10 GAP91209.1 - 2.5e-06 27.4 0.0 5.1e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 GAP91209.1 - 0.0001 21.9 0.0 0.00028 20.5 0.0 1.8 1 0 0 1 1 1 1 Helicase DUF2075 PF09848.4 GAP91209.1 - 0.0012 17.8 1.0 0.0023 16.9 0.0 2.0 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.9 GAP91209.1 - 0.0014 17.6 0.0 0.37 9.7 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase DEAD PF00270.24 GAP91209.1 - 0.002 17.6 0.0 0.0042 16.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.16 GAP91209.1 - 0.0033 16.7 0.0 0.093 12.0 0.0 2.3 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Ribosomal_S13_N PF08069.7 GAP91209.1 - 0.01 15.6 1.0 0.027 14.2 0.0 2.3 3 0 0 3 3 1 0 Ribosomal S13/S15 N-terminal domain AAA_16 PF13191.1 GAP91209.1 - 0.01 15.8 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain KaiC PF06745.8 GAP91209.1 - 0.019 14.0 0.0 0.058 12.5 0.0 1.7 2 0 0 2 2 2 0 KaiC SRP54 PF00448.17 GAP91209.1 - 0.054 12.9 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 GAP91209.1 - 0.076 12.4 0.0 0.15 11.4 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain T2SE PF00437.15 GAP91209.1 - 0.081 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 GAP91209.1 - 0.11 11.7 0.0 0.26 10.4 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.1 GAP91209.1 - 0.11 12.5 0.0 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 GAP91209.1 - 0.12 11.7 0.0 0.29 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 GAP91210.1 - 1.1e-19 70.3 0.0 2.5e-19 69.2 0.0 1.5 2 0 0 2 2 2 1 NB-ARC domain TPR_12 PF13424.1 GAP91210.1 - 2.6e-06 27.2 6.2 3.6e-05 23.6 0.2 4.6 2 1 2 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAP91210.1 - 0.00012 21.7 16.8 0.048 13.5 0.2 6.1 6 0 0 6 6 5 2 Tetratricopeptide repeat AAA_16 PF13191.1 GAP91210.1 - 0.00015 21.8 0.2 0.0018 18.3 0.1 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 GAP91210.1 - 0.0026 17.2 0.0 0.0062 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 GAP91210.1 - 0.014 14.8 0.0 0.036 13.4 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein TPR_11 PF13414.1 GAP91210.1 - 0.014 15.0 11.6 3.2 7.4 0.3 4.8 6 0 0 6 6 5 0 TPR repeat TPR_10 PF13374.1 GAP91210.1 - 0.016 15.1 1.5 3.8 7.5 0.2 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_22 PF13401.1 GAP91210.1 - 0.016 15.3 0.0 0.053 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 GAP91210.1 - 0.043 13.4 0.1 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 NACHT domain ArsA_ATPase PF02374.10 GAP91210.1 - 0.073 12.1 0.0 0.17 10.8 0.0 1.6 1 0 0 1 1 1 0 Anion-transporting ATPase TPR_16 PF13432.1 GAP91210.1 - 0.55 10.9 8.5 0.92 10.2 0.3 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAP91210.1 - 1.1 9.0 9.2 20 4.9 0.2 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Sugar_tr PF00083.19 GAP91211.1 - 5.5e-84 282.3 22.4 1e-82 278.1 15.5 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP91211.1 - 1.5e-32 112.6 32.8 1.1e-30 106.6 17.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAP91211.1 - 0.00023 19.5 5.6 0.00023 19.5 3.8 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Asp_Glu_race PF01177.17 GAP91212.1 - 3.4e-19 69.6 0.0 4.2e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Actin PF00022.14 GAP91213.1 - 9.4e-104 346.9 0.0 1.1e-103 346.7 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 GAP91213.1 - 0.08 11.5 0.0 0.61 8.6 0.0 2.2 2 1 0 2 2 2 0 MreB/Mbl protein Pkinase PF00069.20 GAP91214.1 - 6e-64 215.6 0.0 8e-64 215.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP91214.1 - 2.6e-31 108.6 0.0 4.2e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP91214.1 - 0.0022 17.0 0.0 0.0037 16.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAP91214.1 - 0.028 14.1 0.1 0.41 10.3 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Arf PF00025.16 GAP91215.1 - 5.1e-75 250.5 0.3 6.1e-75 250.2 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 GAP91215.1 - 2.9e-13 49.5 0.0 3.4e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 GAP91215.1 - 3e-12 46.1 0.1 3.8e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 GAP91215.1 - 3.6e-12 45.6 2.1 4.8e-09 35.3 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 GAP91215.1 - 1.6e-11 43.8 0.1 2.1e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 GAP91215.1 - 3.7e-08 33.8 0.0 5.4e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 GAP91215.1 - 0.00038 20.3 0.0 0.00052 19.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 GAP91215.1 - 0.053 12.5 0.3 0.1 11.6 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase DegQ PF08181.6 GAP91215.1 - 0.065 12.9 0.3 0.13 11.9 0.2 1.5 1 0 0 1 1 1 0 DegQ (SacQ) family DRIM PF07539.7 GAP91215.1 - 0.093 12.1 0.3 0.15 11.4 0.2 1.2 1 0 0 1 1 1 0 Down-regulated in metastasis DUF1325 PF07039.6 GAP91216.1 - 1.5e-25 89.3 0.0 2.2e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF1183 PF06682.7 GAP91216.1 - 6.8 6.1 7.0 13 5.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) AAA PF00004.24 GAP91218.1 - 1.9e-19 70.1 0.0 3.7e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAP91218.1 - 0.00075 19.5 0.8 0.0041 17.1 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAP91218.1 - 0.00093 19.3 0.2 0.013 15.6 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 GAP91218.1 - 0.0027 17.9 0.0 0.09 13.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 GAP91218.1 - 0.0058 16.3 0.0 0.013 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 GAP91218.1 - 0.0077 17.0 0.0 0.046 14.5 0.0 2.4 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 GAP91218.1 - 0.23 11.0 0.0 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AA_permease_2 PF13520.1 GAP91219.1 - 2.9e-60 203.9 40.0 3.6e-60 203.7 27.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAP91219.1 - 9.6e-19 67.0 36.4 1.2e-18 66.6 25.3 1.1 1 0 0 1 1 1 1 Amino acid permease HAMP PF00672.20 GAP91219.1 - 4.1 7.6 0.0 4.1 7.6 0.0 4.2 5 0 0 5 5 5 0 HAMP domain SHS2_Rpb7-N PF03876.12 GAP91220.1 - 8.2e-05 22.6 0.0 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DUF2457 PF10446.4 GAP91220.1 - 0.0036 16.1 18.0 0.0036 16.1 12.5 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2457) MIP-T3 PF10243.4 GAP91220.1 - 1.2 7.5 30.0 1.8 6.9 20.8 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 NmrA PF05368.8 GAP91221.1 - 7.2e-29 100.6 0.0 8.7e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 GAP91221.1 - 2.3e-06 26.5 0.2 3.5e-06 25.9 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAP91221.1 - 6.4e-06 25.7 0.7 0.00027 20.4 0.3 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAP91221.1 - 3.3e-05 23.9 3.1 9.9e-05 22.4 1.4 2.3 2 1 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 GAP91221.1 - 0.0012 17.7 0.1 0.0019 17.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 GAP91221.1 - 0.0031 17.4 1.7 0.0047 16.8 0.5 1.7 2 0 0 2 2 2 1 short chain dehydrogenase Saccharop_dh PF03435.13 GAP91221.1 - 0.0036 16.3 0.4 0.0068 15.4 0.3 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 GAP91221.1 - 0.01 16.1 0.4 0.023 15.0 0.1 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 GAP91221.1 - 0.016 14.8 0.2 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 KR domain FliT PF05400.8 GAP91222.1 - 0.0059 16.9 1.5 0.0067 16.8 0.4 1.6 2 0 0 2 2 2 1 Flagellar protein FliT DAP10 PF07213.6 GAP91222.1 - 0.17 11.6 0.6 0.37 10.5 0.4 1.6 1 0 0 1 1 1 0 DAP10 membrane protein Pro_isomerase PF00160.16 GAP91223.1 - 1.5e-33 116.2 0.0 2.4e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 GAP91223.1 - 2.6e-15 55.8 0.0 4.8e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP91223.1 - 9.8e-11 41.4 0.0 1.9e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP91223.1 - 4.3e-10 39.2 0.0 8.7e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.13 GAP91224.1 - 2.6e-07 30.4 5.6 3.6e-07 29.9 3.9 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NDUF_B7 PF05676.8 GAP91226.1 - 7.4e-31 105.3 3.8 8.6e-31 105.1 2.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 GAP91226.1 - 0.008 15.9 2.5 0.0084 15.8 1.3 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like GTP_cyclohydro2 PF00925.15 GAP91228.1 - 1.7e-57 193.3 0.0 1.6e-52 177.1 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II Peptidase_S41 PF03572.13 GAP91229.1 - 7.7e-07 28.6 0.0 3e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 Peptidase family S41 Nsp1_C PF05064.8 GAP91229.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Nsp1-like C-terminal region TRI5 PF06330.6 GAP91230.1 - 4.6e-14 51.8 0.3 6.1e-14 51.4 0.2 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) p450 PF00067.17 GAP91231.1 - 9.7e-38 129.8 0.0 1.2e-37 129.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C14 PF00656.17 GAP91233.1 - 4.6e-36 124.7 0.0 9.9e-36 123.6 0.0 1.6 2 0 0 2 2 2 1 Caspase domain PNP_UDP_1 PF01048.15 GAP91233.1 - 4.2e-12 45.5 0.0 1.1e-11 44.2 0.0 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily zf-C2H2 PF00096.21 GAP91233.1 - 0.0042 17.3 6.8 0.75 10.2 0.2 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP91233.1 - 0.011 16.0 6.9 0.93 9.9 0.2 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger PhyH PF05721.8 GAP91234.1 - 5.1e-26 92.0 0.0 6.9e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fapy_DNA_glyco PF01149.19 GAP91235.1 - 2e-25 89.4 0.1 5.3e-25 88.0 0.0 1.8 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 GAP91235.1 - 1.6e-20 72.6 0.0 2.8e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain SKIP_SNW PF02731.10 GAP91236.1 - 0.32 10.4 1.9 2.6 7.5 0.3 2.2 2 0 0 2 2 2 0 SKIP/SNW domain Ndc80_HEC PF03801.8 GAP91239.1 - 1.6e-64 216.1 0.2 3.3e-64 215.1 0.1 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family THDPS_N_2 PF14805.1 GAP91239.1 - 0.0063 16.3 0.5 0.028 14.2 0.3 2.1 1 0 0 1 1 1 1 Tetrahydrodipicolinate N-succinyltransferase N-terminal FliJ PF02050.11 GAP91239.1 - 0.0089 16.0 4.0 0.0089 16.0 2.8 4.2 2 2 2 4 4 4 3 Flagellar FliJ protein DUF4391 PF14335.1 GAP91239.1 - 0.009 15.4 5.6 0.009 15.4 3.9 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4391) Filament PF00038.16 GAP91239.1 - 0.024 14.1 43.7 0.14 11.6 3.7 3.4 3 1 1 4 4 4 0 Intermediate filament protein V_ATPase_I PF01496.14 GAP91239.1 - 0.13 10.1 25.3 0.2 9.4 8.4 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Tnp_P_element PF12017.3 GAP91239.1 - 2.4 7.3 9.3 2.8 7.0 0.3 2.9 2 1 0 2 2 2 0 Transposase protein Atg14 PF10186.4 GAP91239.1 - 2.4 6.9 28.6 1.4 7.7 4.9 2.5 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 GAP91239.1 - 3.1 6.7 45.7 0.1 11.6 8.8 3.2 2 1 1 3 3 3 0 Autophagy protein Apg6 ApoO PF09769.4 GAP91239.1 - 3.4 7.3 6.2 41 3.8 1.0 3.3 3 0 0 3 3 3 0 Apolipoprotein O Tropomyosin_1 PF12718.2 GAP91239.1 - 3.8 7.3 54.9 0.93 9.3 8.7 4.2 2 2 2 4 4 4 0 Tropomyosin like TPR_MLP1_2 PF07926.7 GAP91239.1 - 3.9 7.2 36.3 4.8 6.9 9.3 3.5 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein GAS PF13851.1 GAP91239.1 - 4.6 6.3 43.4 0.019 14.1 7.5 3.6 2 2 1 3 3 3 0 Growth-arrest specific micro-tubule binding IFT46_B_C PF12317.3 GAP91239.1 - 8.1 5.7 17.4 0.83 8.9 2.9 3.4 2 1 2 4 4 4 0 Intraflagellar transport complex B protein 46 C terminal DUF3584 PF12128.3 GAP91239.1 - 10 3.3 36.7 3 5.0 8.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) ESCRT-II PF05871.7 GAP91240.1 - 1e-47 161.5 0.0 2.8e-47 160.1 0.0 1.7 2 1 0 2 2 2 1 ESCRT-II complex subunit TFIIA PF03153.8 GAP91240.1 - 3.1 7.5 5.5 4.1 7.2 3.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PTCB-BRCT PF12738.2 GAP91241.1 - 3.6e-29 100.3 1.4 2e-19 69.1 0.1 4.5 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 GAP91241.1 - 8.5e-26 89.9 0.0 6.8e-09 35.7 0.0 6.4 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain Pkinase PF00069.20 GAP91242.1 - 2.9e-19 69.2 0.0 3.4e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP91242.1 - 3.7e-08 32.7 0.0 6.5e-08 31.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAP91242.1 - 0.087 12.5 0.2 0.25 11.0 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family TTL PF03133.10 GAP91243.1 - 2.2e-48 164.6 0.0 7.5e-48 162.9 0.0 1.8 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 GAP91243.1 - 2.3e-40 138.0 0.0 3.2e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE ATP-grasp_4 PF13535.1 GAP91243.1 - 0.011 15.4 0.2 0.54 9.9 0.0 2.8 2 1 0 2 2 2 0 ATP-grasp domain ATPgrasp_YheCD PF14398.1 GAP91243.1 - 0.013 14.2 0.0 0.03 13.1 0.0 1.5 1 0 0 1 1 1 0 YheC/D like ATP-grasp Glyco_transf_28 PF03033.15 GAP91243.1 - 0.049 13.3 0.0 0.15 11.7 0.0 1.9 1 1 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Glyco_trans_4_4 PF13579.1 GAP91243.1 - 0.11 12.6 4.2 0.38 10.8 2.6 2.1 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain TFIIA PF03153.8 GAP91243.1 - 3.3 7.5 8.8 0.053 13.4 1.1 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.7 GAP91243.1 - 3.8 6.7 11.4 20 4.3 6.1 2.1 2 0 0 2 2 2 0 SDA1 DASH_Duo1 PF08651.5 GAP91245.1 - 1e-30 105.1 0.6 1.4e-30 104.6 0.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 ARGLU PF15346.1 GAP91245.1 - 0.043 13.5 6.6 0.075 12.8 4.6 1.3 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Syntaxin-6_N PF09177.6 GAP91245.1 - 0.17 12.2 2.2 0.35 11.2 1.5 1.5 1 0 0 1 1 1 0 Syntaxin 6, N-terminal PVL_ORF50 PF07768.6 GAP91245.1 - 0.78 9.7 3.7 4.4 7.3 1.9 2.1 1 1 1 2 2 2 0 PVL ORF-50-like family Lsr2 PF11774.3 GAP91245.1 - 1.5 8.8 9.4 3.7 7.4 6.5 1.7 1 0 0 1 1 1 0 Lsr2 RNase_H2-Ydr279 PF09468.5 GAP91246.1 - 9.9e-83 277.8 0.0 1.6e-82 277.1 0.0 1.3 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Foie-gras_1 PF11817.3 GAP91246.1 - 0.047 13.1 0.4 0.08 12.4 0.3 1.3 1 0 0 1 1 1 0 Foie gras liver health family 1 Dicty_REP PF05086.7 GAP91246.1 - 0.87 7.2 13.1 1.5 6.5 9.1 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-primase PF09329.6 GAP91247.1 - 1.3e-17 63.0 0.2 2.3e-17 62.3 0.1 1.4 1 0 0 1 1 1 1 Primase zinc finger DUF3210 PF11489.3 GAP91248.1 - 1.4e-197 658.6 67.3 1.4e-197 658.6 46.6 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF3210) Cg6151-P PF10233.4 GAP91249.1 - 1.8e-37 127.7 14.4 2.1e-37 127.5 10.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P LMF1 PF06762.9 GAP91249.1 - 0.35 9.5 4.1 0.41 9.3 2.8 1.1 1 0 0 1 1 1 0 Lipase maturation factor DUF1430 PF07242.6 GAP91249.1 - 0.53 10.3 11.1 0.31 11.1 4.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) DUF454 PF04304.8 GAP91249.1 - 1.6 8.8 12.5 2 8.5 2.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF454) COPI_assoc PF08507.5 GAP91249.1 - 3.3 7.4 17.1 5.8 6.5 11.9 1.5 1 1 0 1 1 1 0 COPI associated protein DUF3488 PF11992.3 GAP91249.1 - 3.9 6.0 7.2 5.7 5.4 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) DUF2207 PF09972.4 GAP91249.1 - 8.7 4.7 14.1 6.5 5.2 8.8 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) p450 PF00067.17 GAP91250.1 - 3.9e-31 108.0 0.0 4.4e-30 104.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DOPA_dioxygen PF08883.6 GAP91251.1 - 2.9e-30 104.3 0.1 5e-30 103.6 0.1 1.4 1 1 0 1 1 1 1 Dopa 4,5-dioxygenase family HLH PF00010.21 GAP91252.1 - 2e-17 62.5 0.2 2.6e-16 59.0 0.1 2.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Nnf1 PF03980.9 GAP91252.1 - 0.096 12.6 1.0 0.23 11.4 0.7 1.6 1 0 0 1 1 1 0 Nnf1 Dfp1_Him1_M PF08630.5 GAP91253.1 - 3.3e-39 133.5 0.1 9.7e-39 131.9 0.0 1.8 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 GAP91253.1 - 1.1e-22 79.3 1.0 2.1e-22 78.5 0.7 1.5 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.2 GAP91253.1 - 0.097 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain Ank_5 PF13857.1 GAP91254.1 - 2.1e-19 69.1 0.2 2.9e-08 33.6 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAP91254.1 - 1.4e-18 67.0 0.3 5.8e-09 36.1 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAP91254.1 - 7e-18 63.4 0.5 7.8e-07 28.5 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 GAP91254.1 - 8.2e-14 51.6 0.1 1.2e-07 32.0 0.0 3.7 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP91254.1 - 2e-12 46.0 0.0 0.0039 17.3 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Pyr_redox_2 PF07992.9 GAP91256.1 - 3.7e-15 56.3 0.7 2.8e-14 53.4 0.5 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP91256.1 - 5.7e-05 23.2 0.2 0.00028 21.0 0.0 1.8 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAP91256.1 - 0.00011 22.4 2.2 0.054 13.8 0.3 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAP91256.1 - 0.002 17.0 4.4 0.1 11.5 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAP91256.1 - 0.011 15.5 2.5 2.9 7.6 0.0 3.2 2 2 2 4 4 4 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 GAP91256.1 - 0.012 14.4 1.2 0.095 11.5 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain K_oxygenase PF13434.1 GAP91256.1 - 0.024 13.5 0.0 0.037 12.9 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 GAP91256.1 - 0.043 12.6 0.9 3.8 6.2 0.0 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 GAP91256.1 - 0.083 12.4 0.8 7.6 6.0 0.0 2.5 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 GAP91256.1 - 0.52 9.3 0.0 0.52 9.3 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Fungal_trans PF04082.13 GAP91257.1 - 4.5e-11 42.1 0.0 7e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP91257.1 - 6.4e-09 35.5 8.0 1.3e-08 34.6 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_jaz PF12171.3 GAP91258.1 - 4e-13 49.0 18.1 2.1e-06 27.7 0.4 5.1 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAP91258.1 - 4.4e-12 45.7 19.9 3.8e-06 26.9 0.7 4.7 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 GAP91258.1 - 1.5e-11 43.7 29.2 0.031 14.5 0.7 5.5 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2 PF00096.21 GAP91258.1 - 1.3e-09 37.7 31.8 0.019 15.3 1.6 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 GAP91258.1 - 4.6e-07 29.8 18.8 0.013 15.6 1.2 5.0 2 2 3 5 5 5 3 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 GAP91258.1 - 3e-06 27.2 20.5 0.023 14.9 0.5 5.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_6 PF13912.1 GAP91258.1 - 0.0016 18.2 21.4 0.3 11.0 0.1 5.1 5 0 0 5 5 5 2 C2H2-type zinc finger zf-Di19 PF05605.7 GAP91258.1 - 0.0067 16.5 0.7 0.0067 16.5 0.5 4.5 3 2 1 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding HTH_CodY PF08222.6 GAP91258.1 - 0.015 14.6 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 CodY helix-turn-helix domain HypA PF01155.14 GAP91258.1 - 0.03 14.0 0.1 0.03 14.0 0.1 2.2 2 2 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Trm112p PF03966.11 GAP91258.1 - 0.032 14.5 1.3 0.5 10.7 0.2 2.7 2 2 0 2 2 2 0 Trm112p-like protein zf-LYAR PF08790.6 GAP91258.1 - 0.38 10.4 6.5 7.6 6.3 0.0 3.9 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-Sec23_Sec24 PF04810.10 GAP91258.1 - 0.53 9.9 0.1 0.53 9.9 0.0 3.1 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger zf-C2HC_2 PF13913.1 GAP91258.1 - 1.1 9.0 14.5 2.5 7.8 0.1 4.6 4 1 1 5 5 5 0 zinc-finger of a C2HC-type Rad50_zn_hook PF04423.9 GAP91258.1 - 1.7 8.1 0.0 1.7 8.1 0.0 3.1 4 0 0 4 4 4 0 Rad50 zinc hook motif Zn-ribbon_8 PF09723.5 GAP91258.1 - 2 8.4 18.4 17 5.4 0.5 5.1 4 1 0 4 4 4 0 Zinc ribbon domain zf-DBF PF07535.7 GAP91258.1 - 5.1 6.8 13.4 3 7.6 0.9 3.6 5 0 0 5 5 5 0 DBF zinc finger APH PF01636.18 GAP91259.1 - 5.2e-13 49.2 0.1 4.2e-12 46.3 0.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family VIT PF08487.5 GAP91260.1 - 0.11 12.2 0.1 0.14 11.8 0.1 1.1 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain Asp_Glu_race PF01177.17 GAP91261.1 - 1.5e-17 64.2 0.1 2.4e-17 63.5 0.0 1.3 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase Methyltransf_2 PF00891.13 GAP91262.1 - 1.3e-28 99.8 0.0 1.8e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase APG12 PF04110.8 GAP91263.1 - 6.2e-27 93.6 0.0 7.9e-27 93.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 GAP91263.1 - 8.6e-05 22.4 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.10 GAP91264.1 - 3.2e-100 334.5 1.2 3.6e-100 334.4 0.9 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 GAP91264.1 - 3.9e-09 36.0 0.3 6.2e-09 35.4 0.2 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Racemase_4 PF13615.1 GAP91264.1 - 0.16 12.2 0.0 0.98 9.7 0.0 2.0 2 0 0 2 2 2 0 Putative alanine racemase FAD_binding_4 PF01565.18 GAP91265.1 - 7.3e-16 57.8 3.7 7.3e-16 57.8 2.6 2.3 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 GAP91265.1 - 6e-10 38.8 0.1 2.3e-09 37.0 0.0 2.0 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 GAP91265.1 - 0.0027 16.8 0.0 0.0046 16.1 0.0 1.3 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding Senescence PF06911.7 GAP91266.1 - 0.00016 21.3 4.4 0.00019 21.1 3.0 1.0 1 0 0 1 1 1 1 Senescence-associated protein Chlorosome_CsmC PF11098.3 GAP91266.1 - 0.28 10.8 9.2 0.33 10.6 6.4 1.1 1 0 0 1 1 1 0 Chlorosome envelope protein C SseC PF04888.7 GAP91266.1 - 0.48 9.7 4.8 0.6 9.3 3.3 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family EspB PF05802.6 GAP91266.1 - 2.9 6.7 6.0 3.6 6.4 4.1 1.0 1 0 0 1 1 1 0 Enterobacterial EspB protein dCMP_cyt_deam_1 PF00383.17 GAP91267.1 - 2.2e-06 27.2 0.0 4.8e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Serglycin PF04360.7 GAP91267.1 - 0.022 14.5 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Serglycin Bd3614-deam PF14439.1 GAP91267.1 - 0.15 11.8 0.1 0.15 11.8 0.0 2.7 3 1 0 3 3 3 0 Bd3614-like deaminase EF_assoc_2 PF08356.7 GAP91269.1 - 4.2e-34 116.1 0.0 9e-34 115.1 0.0 1.6 1 0 0 1 1 1 1 EF hand associated Miro PF08477.8 GAP91269.1 - 1.1e-33 116.2 0.0 1.2e-18 67.7 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_1 PF08355.7 GAP91269.1 - 8.4e-32 108.2 0.0 2.1e-31 107.0 0.0 1.7 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 GAP91269.1 - 1.2e-22 79.9 0.0 4.2e-15 55.5 0.0 2.2 2 0 0 2 2 2 2 Ras family EF-hand_7 PF13499.1 GAP91269.1 - 4.6e-08 33.0 0.3 0.0022 18.1 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair MMR_HSR1 PF01926.18 GAP91269.1 - 4.7e-07 29.7 0.0 0.00091 19.1 0.0 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.27 GAP91269.1 - 1.6e-06 27.0 3.5 0.028 13.6 0.5 2.7 2 0 0 2 2 2 2 EF hand AAA_16 PF13191.1 GAP91269.1 - 2.2e-06 27.7 0.1 0.041 13.8 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain EF-hand_6 PF13405.1 GAP91269.1 - 1.2e-05 24.7 6.7 0.016 15.0 0.3 2.7 2 0 0 2 2 2 2 EF-hand domain AAA_22 PF13401.1 GAP91269.1 - 1.7e-05 24.9 0.0 0.2 11.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 GAP91269.1 - 4.6e-05 23.3 0.3 0.13 12.0 0.2 3.2 2 1 1 3 3 3 1 Dynamin family AAA_29 PF13555.1 GAP91269.1 - 5.1e-05 22.7 0.0 0.083 12.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_24 PF13479.1 GAP91269.1 - 0.00016 21.3 0.0 0.057 13.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 GAP91269.1 - 0.00017 21.1 0.0 0.56 9.6 0.0 3.2 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 GAP91269.1 - 0.00057 20.1 0.0 1 9.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter DUF258 PF03193.11 GAP91269.1 - 0.0012 18.0 0.0 1 8.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MobB PF03205.9 GAP91269.1 - 0.002 17.8 0.0 0.13 11.9 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 GAP91269.1 - 0.002 17.8 0.0 1.7 8.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 GAP91269.1 - 0.0021 18.2 0.0 0.35 11.0 0.0 2.5 2 0 0 2 2 2 1 RNA helicase EF-hand_5 PF13202.1 GAP91269.1 - 0.0041 16.4 7.6 0.27 10.6 1.8 2.7 2 0 0 2 2 2 2 EF hand DUF815 PF05673.8 GAP91269.1 - 0.0083 15.0 0.0 1.1 8.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) EF-hand_10 PF14788.1 GAP91269.1 - 0.011 15.3 1.0 0.07 12.8 0.1 2.3 2 0 0 2 2 2 0 EF hand Viral_helicase1 PF01443.13 GAP91269.1 - 0.014 14.9 0.0 0.55 9.7 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.1 GAP91269.1 - 0.022 14.7 0.0 6.1 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 GAP91269.1 - 0.029 13.7 0.0 2 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 GAP91269.1 - 0.046 12.7 0.0 0.47 9.4 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_23 PF13476.1 GAP91269.1 - 0.048 13.9 0.1 5.4 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 GAP91269.1 - 0.053 13.2 0.0 3.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_33 PF13671.1 GAP91269.1 - 0.06 13.2 0.0 12 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain EF-hand_8 PF13833.1 GAP91269.1 - 0.06 12.9 2.5 7.1 6.3 0.4 2.7 2 0 0 2 2 2 0 EF-hand domain pair Arf PF00025.16 GAP91269.1 - 0.14 11.4 0.0 12 5.0 0.0 2.7 2 1 0 2 2 2 0 ADP-ribosylation factor family IIGP PF05049.8 GAP91269.1 - 0.14 10.9 0.0 1.3 7.7 0.0 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) ATP-synt_ab PF00006.20 GAP91269.1 - 0.14 11.5 0.0 0.81 9.1 0.0 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.12 GAP91269.1 - 0.17 11.3 0.1 48 3.3 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DUF87 PF01935.12 GAP91269.1 - 0.21 11.3 0.0 23 4.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 WD40 PF00400.27 GAP91270.1 - 4.8e-23 80.1 4.7 6.8e-06 25.7 0.1 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 GAP91270.1 - 2.9e-05 23.8 0.1 0.00044 20.0 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 GAP91270.1 - 0.22 10.2 0.0 0.39 9.4 0.0 1.3 1 0 0 1 1 1 0 Coatomer WD associated region Arrestin_C PF02752.17 GAP91271.1 - 7.6e-17 61.6 0.0 1.3e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 GAP91271.1 - 1.2e-15 57.6 0.0 2.2e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 GAP91271.1 - 0.016 14.6 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 Arrestin_N terminal like PH PF00169.24 GAP91272.1 - 1.4e-05 25.1 0.0 2.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 PH domain Clr5 PF14420.1 GAP91273.1 - 4.3e-15 55.3 2.9 1.2e-14 53.8 2.0 1.8 1 0 0 1 1 1 1 Clr5 domain Mito_fiss_reg PF05308.6 GAP91273.1 - 0.0037 16.6 1.6 0.0037 16.6 1.1 2.1 2 0 0 2 2 2 1 Mitochondrial fission regulator CAP_N PF01213.14 GAP91273.1 - 0.45 9.7 5.7 1.4 8.1 2.6 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal SR-25 PF10500.4 GAP91273.1 - 9.8 5.5 8.3 19 4.6 5.7 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein EthD PF07110.6 GAP91274.1 - 0.041 14.8 0.1 0.06 14.2 0.0 1.4 1 1 0 1 1 1 0 EthD domain Lipase_GDSL PF00657.17 GAP91275.1 - 6.6e-15 55.5 0.9 9.7e-15 55.0 0.6 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 GAP91275.1 - 2.1e-06 28.0 5.2 6.2e-06 26.4 3.6 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family RNase_H PF00075.19 GAP91276.1 - 1.1e-07 32.2 0.1 6.5e-07 29.7 0.1 1.9 1 1 0 1 1 1 1 RNase H DUF2937 PF11157.3 GAP91277.1 - 0.2 11.0 1.3 0.29 10.4 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) SKG6 PF08693.5 GAP91277.1 - 0.31 10.3 6.8 0.15 11.4 2.0 2.4 3 0 0 3 3 3 0 Transmembrane alpha-helix domain CD99L2 PF12301.3 GAP91277.1 - 0.75 9.4 9.4 3.1 7.4 1.0 2.3 2 0 0 2 2 2 0 CD99 antigen like protein 2 Peptidase_S66 PF02016.10 GAP91278.1 - 1.6e-52 178.1 0.0 2e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 LD-carboxypeptidase Abhydrolase_2 PF02230.11 GAP91279.1 - 3.4e-22 78.9 0.0 1.4e-15 57.3 0.1 2.8 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 GAP91279.1 - 0.0023 17.7 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAP91279.1 - 0.0042 16.3 0.0 0.0066 15.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 GAP91279.1 - 0.0046 16.8 4.7 0.0046 16.8 3.2 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Sulfatase PF00884.18 GAP91280.1 - 2.8e-58 197.5 0.3 3.5e-58 197.2 0.2 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 GAP91280.1 - 1.1e-05 24.9 4.8 0.00014 21.2 3.4 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 GAP91280.1 - 0.14 10.5 0.0 0.23 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Sugar_tr PF00083.19 GAP91281.1 - 2.1e-72 244.1 14.0 2.8e-72 243.7 9.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP91281.1 - 6.8e-17 61.2 37.7 5.5e-10 38.4 11.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.2 GAP91282.1 - 1.7e-15 57.0 0.3 4.6e-09 36.5 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAP91282.1 - 1.6e-07 31.6 0.0 0.05 14.1 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 GAP91282.1 - 3.3e-06 26.6 0.2 0.027 14.2 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 GAP91282.1 - 0.0025 17.9 0.0 3.5 7.9 0.0 3.6 2 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP91282.1 - 0.0059 16.7 0.2 19 5.8 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat TPR_12 PF13424.1 GAP91282.1 - 0.016 15.1 0.3 0.068 13.1 0.2 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat RUN PF02759.14 GAP91282.1 - 0.21 11.3 1.4 0.76 9.5 0.4 2.3 2 1 0 2 2 2 0 RUN domain UPF0029 PF01205.14 GAP91283.1 - 2.1e-22 78.8 0.0 4.1e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Methyltransf_23 PF13489.1 GAP91284.1 - 1.1e-11 44.7 0.0 2.7e-11 43.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP91284.1 - 0.00066 20.1 0.0 0.5 10.8 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 GAP91284.1 - 0.074 13.4 0.0 0.63 10.4 0.0 2.5 3 1 0 3 3 3 0 Methyltransferase domain MFS_1 PF07690.11 GAP91287.1 - 1.1e-29 103.3 29.6 1.1e-29 103.2 14.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PDGLE PF13190.1 GAP91287.1 - 0.066 12.8 0.0 0.23 11.1 0.0 2.0 1 0 0 1 1 1 0 PDGLE domain Prominin PF05478.6 GAP91287.1 - 0.52 7.7 1.0 0.85 7.0 0.7 1.2 1 0 0 1 1 1 0 Prominin Na_H_Exchanger PF00999.16 GAP91289.1 - 4.3e-18 65.0 18.6 6.8e-17 61.0 12.9 2.0 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Not1 PF04054.10 GAP91290.1 - 8.4e-82 275.0 0.0 1.9e-81 273.9 0.0 1.6 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 GAP91290.1 - 7.5e-48 161.9 2.4 2.2e-47 160.4 1.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) FAD_binding_4 PF01565.18 GAP91291.1 - 2e-18 66.2 0.4 3.9e-18 65.2 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP91291.1 - 1.1e-13 50.8 0.1 2.1e-13 49.9 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like DinB PF05163.7 GAP91292.1 - 0.16 11.6 0.2 0.38 10.4 0.1 1.6 1 1 1 2 2 2 0 DinB family His_Phos_1 PF00300.17 GAP91293.1 - 9.3e-07 29.0 0.0 3.3e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) FUSC_2 PF13515.1 GAP91294.1 - 3.5e-12 46.3 31.1 3e-09 36.8 5.1 2.9 2 1 1 3 3 3 2 Fusaric acid resistance protein-like DUF2422 PF10337.4 GAP91294.1 - 1.2e-08 34.2 0.9 1.2e-08 34.2 0.6 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 GAP91294.1 - 7.5e-05 22.4 0.0 0.00015 21.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) ALMT PF11744.3 GAP91294.1 - 0.043 12.4 0.0 0.043 12.4 0.0 2.4 3 0 0 3 3 3 0 Aluminium activated malate transporter NTF2 PF02136.15 GAP91295.1 - 2.7e-17 63.2 0.1 3e-17 63.0 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain HECT PF00632.20 GAP91296.1 - 2.2e-82 276.7 0.0 3.9e-82 275.9 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 GAP91296.1 - 0.0019 17.6 0.9 0.0054 16.2 0.6 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Sugar_tr PF00083.19 GAP91297.1 - 2.9e-101 339.3 21.3 3.7e-101 338.9 14.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Sulfatase PF00884.18 GAP91297.1 - 6.5e-38 130.6 0.7 9.2e-37 126.8 0.0 2.4 2 1 1 3 3 3 1 Sulfatase MFS_1 PF07690.11 GAP91297.1 - 1.1e-25 90.0 41.1 9.9e-20 70.5 7.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAP91297.1 - 4.8e-06 25.0 1.7 4.8e-06 25.0 1.2 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) UNC-93 PF05978.11 GAP91297.1 - 0.00029 20.3 3.3 0.00029 20.3 2.3 3.1 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_3 PF05977.8 GAP91297.1 - 0.0024 16.0 0.7 0.0046 15.1 0.5 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector Zn_clus PF00172.13 GAP91298.1 - 3.3e-06 26.9 10.5 5.7e-06 26.1 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 GAP91299.1 - 3.5e-62 210.4 0.0 4.5e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 GAP91300.1 - 8.7e-27 93.9 0.0 1.5e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 GAP91300.1 - 1.5e-26 93.1 0.0 2.6e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 GAP91300.1 - 8.9e-09 35.8 0.0 2.6e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain RRM_1 PF00076.17 GAP91301.1 - 1.4e-84 277.7 8.1 2.3e-22 78.3 0.1 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP91301.1 - 5.3e-55 183.2 1.9 4.6e-15 55.3 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP91301.1 - 3.1e-42 142.1 0.6 4.4e-11 42.4 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 GAP91301.1 - 1.5e-27 95.0 0.6 6.1e-27 93.1 0.3 2.1 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 GAP91301.1 - 0.00018 21.2 0.3 3 7.6 0.0 4.7 4 1 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 GAP91301.1 - 0.015 14.9 2.1 1.7 8.4 0.1 3.6 3 0 0 3 3 3 0 Limkain b1 CbiG_mid PF11761.3 GAP91301.1 - 0.02 15.1 1.6 4.1 7.6 0.0 4.2 5 0 0 5 5 5 0 Cobalamin biosynthesis central region Nab6_mRNP_bdg PF10567.4 GAP91301.1 - 0.037 12.9 0.5 0.11 11.4 0.1 1.9 2 0 0 2 2 2 0 RNA-recognition motif OB_RNB PF08206.6 GAP91301.1 - 0.059 12.8 2.3 6.6 6.3 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain NPV_P10 PF05531.7 GAP91302.1 - 0.0025 18.0 0.5 0.0064 16.7 0.3 1.6 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein KCNQ_channel PF03520.9 GAP91302.1 - 0.0042 16.4 0.1 0.0081 15.4 0.1 1.4 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel IncA PF04156.9 GAP91302.1 - 0.0092 15.5 0.5 0.098 12.2 0.0 2.2 2 0 0 2 2 2 1 IncA protein CENP-F_leu_zip PF10473.4 GAP91302.1 - 0.015 15.1 0.8 0.076 12.8 0.2 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.4 GAP91302.1 - 0.024 14.7 3.2 0.12 12.4 0.3 3.2 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TBPIP PF07106.8 GAP91302.1 - 0.037 13.5 0.8 0.085 12.4 0.1 1.8 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Prefoldin_2 PF01920.15 GAP91302.1 - 0.041 13.6 3.4 0.25 11.0 0.3 2.7 2 1 0 2 2 2 0 Prefoldin subunit Syntaxin PF00804.20 GAP91302.1 - 0.045 13.9 2.3 0.18 11.9 0.8 2.4 2 0 0 2 2 2 0 Syntaxin DUF1664 PF07889.7 GAP91302.1 - 0.046 13.5 0.6 0.21 11.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.10 GAP91302.1 - 0.064 12.7 0.8 0.24 10.9 0.1 2.2 2 0 0 2 2 2 0 Septum formation initiator V_ATPase_I PF01496.14 GAP91302.1 - 0.11 10.3 0.4 0.2 9.4 0.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LPP PF04728.8 GAP91302.1 - 0.19 11.5 2.5 0.44 10.3 1.2 2.0 2 0 0 2 2 1 0 Lipoprotein leucine-zipper Fmp27_WPPW PF10359.4 GAP91302.1 - 0.21 9.9 4.3 0.37 9.1 3.0 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Allexi_40kDa PF05549.6 GAP91302.1 - 0.26 10.5 2.7 0.47 9.7 1.9 1.5 1 0 0 1 1 1 0 Allexivirus 40kDa protein Uds1 PF15456.1 GAP91302.1 - 0.41 10.6 6.1 2.7 7.9 1.3 3.1 2 1 0 2 2 2 0 Up-regulated During Septation DUF972 PF06156.8 GAP91302.1 - 0.64 10.3 4.0 0.62 10.4 1.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Enkurin PF13864.1 GAP91302.1 - 0.7 10.1 3.7 8 6.7 0.1 3.0 3 0 0 3 3 3 0 Calmodulin-binding Reo_sigmaC PF04582.7 GAP91302.1 - 2.4 7.2 7.1 4.2 6.4 4.9 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TPR_11 PF13414.1 GAP91303.1 - 0.00023 20.7 0.0 0.012 15.2 0.0 2.5 2 1 0 2 2 2 2 TPR repeat TPR_14 PF13428.1 GAP91303.1 - 0.05 14.2 0.0 61 4.6 0.0 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat GMC_oxred_N PF00732.14 GAP91305.1 - 5.2e-57 193.2 0.0 7.3e-57 192.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAP91305.1 - 3.4e-32 111.7 0.0 7.1e-32 110.6 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAP91305.1 - 1.5e-08 33.9 0.2 0.0027 16.6 0.2 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAP91305.1 - 3.7e-08 32.6 0.5 0.003 16.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAP91305.1 - 6.3e-05 22.9 0.2 0.00017 21.5 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAP91305.1 - 0.0011 19.0 0.2 0.013 15.5 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAP91305.1 - 0.0013 18.6 0.1 0.46 10.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAP91305.1 - 0.0085 15.1 0.1 0.11 11.4 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 GAP91305.1 - 0.01 14.9 0.3 0.021 13.9 0.2 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 GAP91305.1 - 0.013 15.2 0.3 0.062 13.0 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.13 GAP91305.1 - 0.017 15.1 0.2 0.067 13.1 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.9 GAP91305.1 - 0.027 12.9 0.3 0.061 11.7 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 GAP91305.1 - 0.038 12.8 0.1 0.061 12.2 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein ThiF PF00899.16 GAP91305.1 - 0.12 12.1 0.8 3.3 7.5 0.1 2.3 2 0 0 2 2 2 0 ThiF family Ceramidase PF05875.7 GAP91306.1 - 3.4e-54 183.7 1.1 3.7e-54 183.6 0.8 1.0 1 0 0 1 1 1 1 Ceramidase Leader_Trp PF08255.6 GAP91306.1 - 3.8 7.4 7.9 0.78 9.5 1.9 2.6 2 0 0 2 2 2 0 Trp-operon Leader Peptide TPR_12 PF13424.1 GAP91307.1 - 9e-08 31.9 5.8 5.8e-07 29.3 0.4 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAP91307.1 - 8.2e-05 22.1 4.2 0.019 14.7 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat Peptidase_C97 PF05903.9 GAP91307.1 - 0.00012 21.8 0.1 0.0003 20.6 0.1 1.6 1 0 0 1 1 1 1 PPPDE putative peptidase domain TPR_10 PF13374.1 GAP91307.1 - 0.00023 20.9 2.8 0.068 13.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAP91307.1 - 0.0034 17.1 4.1 0.97 9.5 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAP91307.1 - 0.04 13.5 0.2 0.04 13.5 0.1 2.6 3 0 0 3 3 3 0 TPR repeat TPR_17 PF13431.1 GAP91307.1 - 0.054 13.7 0.0 0.41 10.9 0.0 2.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAP91307.1 - 0.062 13.6 5.5 0.84 10.0 0.1 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF4351 PF14261.1 GAP91307.1 - 0.076 12.8 0.3 0.48 10.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) TPR_14 PF13428.1 GAP91307.1 - 0.078 13.6 8.0 1.2 9.9 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat LRAT PF04970.8 GAP91307.1 - 0.08 12.8 0.2 0.54 10.2 0.0 2.2 2 0 0 2 2 2 0 Lecithin retinol acyltransferase TPR_16 PF13432.1 GAP91307.1 - 0.24 12.0 9.5 0.069 13.8 0.6 4.1 4 1 1 5 5 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAP91307.1 - 0.36 10.5 3.6 2.5 7.8 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAP91307.1 - 0.77 10.3 6.9 5.2 7.7 0.1 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat GST_C PF00043.20 GAP91309.1 - 9.8e-15 54.3 0.0 1.7e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAP91309.1 - 1.4e-11 44.3 0.0 6e-11 42.3 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAP91309.1 - 1.1e-09 38.3 0.0 2.1e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAP91309.1 - 1.7e-09 37.5 0.0 4.7e-09 36.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAP91309.1 - 4.7e-08 32.8 0.0 8.2e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAP91309.1 - 7.5e-07 29.5 0.1 1.3e-06 28.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Aconitase PF00330.15 GAP91310.1 - 5.5e-73 246.0 0.0 4.7e-46 157.2 0.0 2.2 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 GAP91310.1 - 1e-18 67.7 0.0 1.9e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain AAA_13 PF13166.1 GAP91311.1 - 5e-05 21.9 10.5 6e-05 21.7 7.3 1.2 1 0 0 1 1 1 1 AAA domain BLOC1_2 PF10046.4 GAP91311.1 - 0.0003 20.8 3.2 0.0003 20.8 2.2 2.6 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.7 GAP91311.1 - 0.0007 19.7 10.4 0.0089 16.2 0.6 2.9 3 0 0 3 3 3 2 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 GAP91311.1 - 0.018 14.9 8.4 0.29 10.9 0.3 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 GAP91311.1 - 0.047 12.8 0.3 0.047 12.8 0.2 2.2 2 1 0 2 2 2 0 Reovirus sigma C capsid protein ATP-synt_F PF01990.12 GAP91311.1 - 0.099 13.0 2.5 0.31 11.4 0.1 2.5 2 0 0 2 2 2 0 ATP synthase (F/14-kDa) subunit DUF4201 PF13870.1 GAP91311.1 - 0.1 12.0 16.8 0.17 11.3 0.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Bacillus_HBL PF05791.6 GAP91311.1 - 0.13 11.6 6.0 0.39 10.0 0.7 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF972 PF06156.8 GAP91311.1 - 0.16 12.2 16.3 1 9.7 1.3 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF972) IncA PF04156.9 GAP91311.1 - 0.23 11.0 30.9 0.22 11.1 4.3 2.9 2 1 1 3 3 3 0 IncA protein Spc7 PF08317.6 GAP91311.1 - 0.38 9.3 21.2 0.15 10.6 12.4 2.0 2 1 0 2 2 2 0 Spc7 kinetochore protein FliD_C PF07195.7 GAP91311.1 - 0.41 9.9 4.4 2.4 7.4 0.2 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Fib_alpha PF08702.5 GAP91311.1 - 0.46 10.5 10.8 8.1 6.5 5.5 3.0 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family MbeD_MobD PF04899.7 GAP91311.1 - 0.47 10.3 5.6 3.3 7.6 1.0 3.0 3 0 0 3 3 2 0 MbeD/MobD like Prefoldin PF02996.12 GAP91311.1 - 0.56 9.8 14.0 2.1 7.9 2.3 3.0 2 1 0 2 2 2 0 Prefoldin subunit PhaP_Bmeg PF09602.5 GAP91311.1 - 0.7 9.7 9.9 0.31 10.8 3.2 2.7 2 1 1 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Syntaxin-6_N PF09177.6 GAP91311.1 - 0.74 10.2 9.5 3.3 8.1 0.3 3.1 2 1 0 3 3 2 0 Syntaxin 6, N-terminal DUF745 PF05335.8 GAP91311.1 - 0.89 9.0 16.2 4 6.9 10.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF745) HrpA_pilin PF09589.5 GAP91311.1 - 0.91 9.9 4.7 3.6 8.0 0.1 2.5 1 1 1 2 2 2 0 HrpA pilus formation protein COG5 PF10392.4 GAP91311.1 - 0.93 9.4 11.7 0.39 10.6 0.3 2.8 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Laminin_II PF06009.7 GAP91311.1 - 1.1 9.0 14.6 0.9 9.2 0.5 3.0 3 0 0 3 3 3 0 Laminin Domain II ADIP PF11559.3 GAP91311.1 - 1.1 9.0 20.8 0.21 11.4 4.3 2.9 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Spc24 PF08286.6 GAP91311.1 - 1.4 8.6 16.9 0.2 11.3 2.6 3.0 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 DUF948 PF06103.6 GAP91311.1 - 1.9 8.3 6.1 7.3 6.5 0.2 2.7 2 1 0 3 3 2 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.6 GAP91311.1 - 2 8.3 6.5 47 3.9 0.1 3.6 1 1 1 3 3 3 0 Flagella accessory protein C (FlaC) HrpB7 PF09486.5 GAP91311.1 - 3.6 7.4 21.8 0.86 9.5 0.8 3.6 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) FlxA PF14282.1 GAP91311.1 - 4 7.4 16.0 15 5.5 7.7 3.2 2 1 1 3 3 3 0 FlxA-like protein Prefoldin_2 PF01920.15 GAP91311.1 - 5 6.9 18.3 8.9 6.1 3.4 3.4 3 1 0 3 3 2 0 Prefoldin subunit SlyX PF04102.7 GAP91311.1 - 6 7.3 19.1 7.2 7.0 2.9 4.4 2 1 2 4 4 4 0 SlyX ERM PF00769.14 GAP91311.1 - 6 6.3 31.1 0.33 10.4 8.4 2.7 2 1 1 3 3 3 0 Ezrin/radixin/moesin family HAUS5 PF14817.1 GAP91311.1 - 7.7 4.9 24.9 0.39 9.1 7.6 2.5 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 ATG16 PF08614.6 GAP91311.1 - 7.8 6.2 25.2 5.9 6.6 6.5 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Fzo_mitofusin PF04799.8 GAP91311.1 - 8.5 5.7 9.7 3.6 6.9 0.3 2.6 3 0 0 3 3 3 0 fzo-like conserved region Microtub_assoc PF07989.6 GAP91311.1 - 9.7 6.0 11.9 0.66 9.8 0.8 3.3 3 0 0 3 3 2 0 Microtubule associated Abhydrolase_6 PF12697.2 GAP91314.1 - 2.2e-28 99.7 0.1 2.6e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP91314.1 - 1.3e-14 54.3 0.0 1.2e-13 51.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP91314.1 - 1.7e-12 47.2 0.0 3.1e-11 43.2 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 GAP91314.1 - 0.0018 17.7 0.0 0.0039 16.6 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 GAP91314.1 - 0.0042 16.9 0.0 0.0091 15.8 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase LIP PF03583.9 GAP91315.1 - 7.6e-62 209.1 0.0 1.1e-61 208.6 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 GAP91315.1 - 0.0002 21.3 0.1 0.00031 20.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 GAP91316.1 - 5.4e-40 137.2 0.1 9.1e-40 136.4 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP91316.1 - 0.0004 20.1 0.1 0.00065 19.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 GAP91316.1 - 0.0012 17.6 0.4 0.0023 16.7 0.0 1.6 2 0 0 2 2 2 1 Carboxylesterase family Semialdhyde_dhC PF02774.13 GAP91317.1 - 2e-39 135.3 0.0 2.5e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 GAP91317.1 - 4.1e-29 101.3 0.0 1.3e-28 99.6 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 GAP91317.1 - 0.003 17.4 0.0 0.0058 16.5 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 GAP91317.1 - 0.01 16.3 0.0 0.026 15.0 0.0 1.8 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase GFO_IDH_MocA PF01408.17 GAP91317.1 - 0.071 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DUF619 PF04768.8 GAP91318.1 - 6.7e-48 162.3 0.5 1.3e-47 161.4 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF619) AA_kinase PF00696.23 GAP91318.1 - 5e-26 91.7 0.0 9.3e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family Synaptobrevin PF00957.16 GAP91319.1 - 9.2e-34 114.9 1.6 1e-33 114.7 1.1 1.0 1 0 0 1 1 1 1 Synaptobrevin HET PF06985.6 GAP91320.1 - 2.7e-26 92.3 0.0 9.3e-26 90.6 0.0 2.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ldh_1_N PF00056.18 GAP91321.1 - 3.6e-32 111.1 0.0 5.2e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 GAP91321.1 - 1.3e-24 86.8 0.0 2.3e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain UDPG_MGDP_dh_N PF03721.9 GAP91321.1 - 0.019 14.3 0.3 0.22 10.9 0.2 2.3 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 GAP91321.1 - 0.022 15.1 0.1 0.13 12.7 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 GAP91321.1 - 0.05 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Gp_dh_N PF00044.19 GAP91321.1 - 0.073 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain WXG100 PF06013.7 GAP91322.1 - 0.045 13.7 0.0 0.44 10.5 0.0 2.5 2 0 0 2 2 2 0 Proteins of 100 residues with WXG SH3_6 PF12913.2 GAP91323.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 SH3 domain of the SH3b1 type Glyco_hydro_76 PF03663.9 GAP91324.1 - 6.3e-149 496.3 21.8 8e-149 496.0 15.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 SKG6 PF08693.5 GAP91325.1 - 0.43 9.9 3.0 0.64 9.3 2.1 1.2 1 0 0 1 1 1 0 Transmembrane alpha-helix domain tRNA-synt_His PF13393.1 GAP91326.1 - 1.6e-40 139.0 0.0 2.1e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 GAP91326.1 - 1.9e-17 63.3 0.0 3.5e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAP91326.1 - 2.1e-12 46.8 0.0 6.5e-12 45.2 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 GAP91326.1 - 0.00027 19.8 0.0 0.0045 15.7 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF4062 PF13271.1 GAP91326.1 - 0.0086 16.0 0.2 0.13 12.3 0.0 2.7 2 1 0 3 3 3 1 Domain of unknown function (DUF4062) tRNA-synt_2d PF01409.15 GAP91326.1 - 0.0098 15.1 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) DUF4473 PF14747.1 GAP91326.1 - 0.043 14.0 2.4 0.61 10.3 1.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4473) POP1 PF06978.6 GAP91327.1 - 8.7e-57 191.8 11.2 1.4e-56 191.0 7.7 1.4 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 GAP91327.1 - 1.3e-30 105.0 0.2 3.6e-30 103.6 0.1 1.8 1 0 0 1 1 1 1 POPLD (NUC188) domain NT-C2 PF10358.4 GAP91328.1 - 1.6e-23 82.7 0.0 1.1e-22 80.0 0.0 2.0 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins HSP70 PF00012.15 GAP91329.1 - 3.8e-79 266.2 1.2 5.5e-79 265.6 0.8 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAP91329.1 - 4.1e-07 28.9 0.1 7.2e-07 28.1 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein Hydantoinase_A PF01968.13 GAP91329.1 - 0.008 15.3 0.4 0.047 12.7 0.0 2.2 1 1 0 2 2 2 1 Hydantoinase/oxoprolinase FtsA PF14450.1 GAP91329.1 - 0.054 13.3 0.4 1.8 8.4 0.1 2.6 2 0 0 2 2 2 0 Cell division protein FtsA Peroxidase_2 PF01328.12 GAP91331.1 - 2.3e-26 92.2 0.0 3.6e-26 91.5 0.0 1.3 1 1 0 1 1 1 1 Peroxidase, family 2 2OG-FeII_Oxy_2 PF13532.1 GAP91332.1 - 3.6e-19 69.3 0.0 6.5e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CorA PF01544.13 GAP91333.1 - 5.5e-08 32.1 5.9 6.9e-08 31.8 3.4 1.6 1 1 1 2 2 2 1 CorA-like Mg2+ transporter protein CCDC92 PF14916.1 GAP91333.1 - 0.052 13.1 0.6 0.11 12.0 0.4 1.5 1 0 0 1 1 1 0 Coiled-coil domain of unknown function Toxin_42 PF15522.1 GAP91333.1 - 0.15 11.2 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Putative toxin 42 FAD_binding_3 PF01494.14 GAP91334.1 - 3e-65 220.6 0.0 4.2e-65 220.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain MFS_1 PF07690.11 GAP91334.1 - 1.4e-16 60.1 61.3 2.4e-12 46.2 21.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DAO PF01266.19 GAP91334.1 - 5e-06 25.6 0.5 0.001 18.0 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 GAP91334.1 - 1.2e-05 24.0 0.3 0.00039 19.0 0.1 2.3 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 GAP91334.1 - 1.7e-05 24.9 0.1 5.2e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAP91334.1 - 2.8e-05 23.4 0.0 4.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAP91334.1 - 0.00015 21.7 0.0 0.00059 19.7 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAP91334.1 - 0.00022 20.2 0.7 0.0022 17.0 0.4 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 GAP91334.1 - 0.00046 20.1 0.1 0.0011 18.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAP91334.1 - 0.0018 17.1 0.1 0.0029 16.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 GAP91334.1 - 0.0019 18.5 0.0 0.015 15.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAP91334.1 - 0.027 14.2 0.6 3.2 7.5 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Methyltransf_18 PF12847.2 GAP91334.1 - 0.063 13.8 0.0 0.24 12.0 0.0 2.0 2 0 0 2 2 1 0 Methyltransferase domain Thi4 PF01946.12 GAP91334.1 - 0.065 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DIT1_PvcA PF05141.7 GAP91335.1 - 2.7e-88 295.8 0.0 3.5e-88 295.5 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.11 GAP91335.1 - 1.7e-24 86.9 0.0 5.9e-24 85.1 0.0 1.8 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_hydro_43 PF04616.9 GAP91336.1 - 4.9e-40 137.4 3.5 6.9e-40 136.9 2.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CW_binding_1 PF01473.15 GAP91336.1 - 5.2 7.3 11.7 9.5 6.5 1.2 4.1 3 0 0 3 3 3 0 Putative cell wall binding repeat p450 PF00067.17 GAP91337.1 - 2.3e-34 118.7 0.0 8.9e-26 90.4 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Tannase PF07519.6 GAP91338.1 - 3.9e-70 236.8 1.7 1.6e-53 182.0 0.4 2.0 1 1 1 2 2 2 2 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 GAP91338.1 - 0.00034 20.5 0.4 0.018 14.9 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP91338.1 - 0.0029 17.2 0.5 0.01 15.4 0.1 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAP91338.1 - 0.039 13.1 0.1 0.07 12.3 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.23 GAP91339.1 - 2.2e-94 317.0 0.0 3e-94 316.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAP91339.1 - 5.5e-11 42.4 1.5 2.2e-10 40.4 0.4 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAP91339.1 - 0.0027 16.9 0.4 0.0047 16.1 0.3 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAP91339.1 - 0.019 14.7 0.2 0.032 13.9 0.2 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family CBM-like PF14683.1 GAP91340.1 - 6.1e-24 84.5 0.0 1.2e-11 44.5 0.0 2.6 1 1 1 2 2 2 2 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 GAP91340.1 - 4.2e-17 62.0 0.0 4.2e-17 62.0 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 GAP91340.1 - 2.1e-05 24.4 0.2 4.2e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4198 PF10670.4 GAP91340.1 - 0.00027 21.0 0.0 0.00064 19.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4198) DUF4619 PF15398.1 GAP91340.1 - 0.16 11.3 0.6 0.27 10.6 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) zf-DHHC PF01529.15 GAP91341.1 - 1.5e-39 135.1 0.1 3e-39 134.1 0.0 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Yip1 PF04893.12 GAP91341.1 - 0.03 13.8 0.3 0.03 13.8 0.2 1.8 2 0 0 2 2 2 0 Yip1 domain ABC2_membrane_4 PF12730.2 GAP91341.1 - 1.8 7.6 6.9 1.4 8.0 1.4 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein HAD PF12710.2 GAP91343.1 - 3.5e-19 69.7 0.0 5e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAP91343.1 - 6.7e-13 49.5 1.7 2.3e-11 44.4 1.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAP91343.1 - 1.1e-08 34.9 0.8 2.7e-07 30.4 0.0 2.7 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 GAP91343.1 - 3.2e-06 27.4 0.0 6.7e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF705 PF05152.7 GAP91343.1 - 0.0011 18.0 0.1 0.0015 17.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF705) Put_Phosphatase PF06888.7 GAP91343.1 - 0.029 13.5 0.1 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Putative Phosphatase Acid_PPase PF12689.2 GAP91343.1 - 0.16 11.5 0.0 0.61 9.6 0.0 2.0 1 1 0 1 1 1 0 Acid Phosphatase PAPS_reduct PF01507.14 GAP91344.1 - 9.2e-39 133.0 0.0 1.7e-38 132.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF2281 PF10047.4 GAP91344.1 - 0.046 14.0 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) Daxx PF03344.10 GAP91345.1 - 0.53 8.7 4.8 0.96 7.8 3.3 1.4 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 GAP91345.1 - 8.7 4.1 12.9 14 3.4 8.9 1.2 1 0 0 1 1 1 0 Nop14-like family Complex1_LYR_1 PF13232.1 GAP91346.1 - 1.4e-20 73.2 1.6 1.4e-20 73.2 1.1 2.4 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.10 GAP91346.1 - 1.1e-19 69.9 2.1 1.1e-19 69.9 1.5 2.9 2 1 1 3 3 3 1 Complex 1 protein (LYR family) Ecl1 PF12855.2 GAP91346.1 - 0.08 12.2 1.3 0.21 10.8 0.9 1.7 1 0 0 1 1 1 0 Life-span regulatory factor Complex1_LYR_2 PF13233.1 GAP91346.1 - 1.4 9.4 6.2 0.26 11.8 0.2 2.7 2 1 0 2 2 2 0 Complex1_LYR-like DUF3330 PF11809.3 GAP91346.1 - 3.9 7.4 8.9 10 6.1 1.0 3.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3330) zf-MYND PF01753.13 GAP91346.1 - 5.9 6.8 16.0 0.14 12.0 2.2 3.3 3 0 0 3 3 3 0 MYND finger MAGE PF01454.14 GAP91347.1 - 4e-44 150.2 0.0 5e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 MAGE family SLS PF14611.1 GAP91348.1 - 1.3e-28 99.9 0.6 1.3e-28 99.9 0.4 1.9 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator Antimicrobial_5 PF08026.6 GAP91348.1 - 2.8 7.8 8.2 0.41 10.5 2.5 2.0 2 0 0 2 2 2 0 Bee antimicrobial peptide GTP_EFTU PF00009.22 GAP91349.1 - 1.1e-56 191.2 0.1 1.6e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 GAP91349.1 - 2.4e-36 123.8 0.1 6.8e-36 122.4 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 GAP91349.1 - 5.1e-16 58.5 0.7 5.1e-16 58.5 0.5 2.5 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAP91349.1 - 0.00079 19.3 0.1 0.0024 17.8 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase EOS1 PF12326.3 GAP91350.1 - 8.3e-24 83.9 13.7 3.5e-20 72.1 5.7 2.2 1 1 1 2 2 2 2 N-glycosylation protein MFS_1 PF07690.11 GAP91351.1 - 5.5e-37 127.2 36.6 8.8e-30 103.6 11.1 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP91351.1 - 4.9e-15 55.0 9.1 4.9e-15 55.0 6.3 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 GAP91351.1 - 0.00027 19.2 5.8 0.00027 19.2 4.0 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2348 PF09807.4 GAP91352.1 - 3.3e-08 32.9 0.0 9.1e-07 28.2 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2348) Autophagy_N PF03986.8 GAP91353.1 - 1.1e-46 158.1 0.7 1.5e-46 157.8 0.0 1.5 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 GAP91353.1 - 7.4e-24 83.7 0.2 1.8e-23 82.5 0.1 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 GAP91353.1 - 1.4e-14 52.8 0.4 2.4e-14 52.0 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Xan_ur_permease PF00860.15 GAP91354.1 - 1.8e-26 92.5 29.7 9.1e-26 90.2 18.8 2.6 2 1 0 2 2 2 1 Permease family DUF718 PF05336.8 GAP91355.1 - 5.5e-34 116.1 0.0 5.5e-34 116.1 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF718) Pex16 PF08610.5 GAP91355.1 - 0.99 8.3 4.8 1.4 7.8 3.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) PAT1 PF09770.4 GAP91355.1 - 5 5.2 15.1 5.3 5.1 10.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PHD_3 PF13922.1 GAP91355.1 - 5.1 7.4 6.1 7.8 6.8 4.2 1.3 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx DUF4175 PF13779.1 GAP91355.1 - 9.5 3.7 13.0 12 3.4 9.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) UPF0016 PF01169.14 GAP91356.1 - 3.8e-42 142.3 24.9 3.3e-22 78.4 5.2 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Myb_DNA-bind_4 PF13837.1 GAP91357.1 - 0.012 15.7 0.1 0.034 14.2 0.1 1.8 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain MBA1 PF07961.6 GAP91358.1 - 1.4e-08 33.8 0.0 1.8e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.10 GAP91358.1 - 5.7e-05 23.1 0.1 0.00015 21.7 0.1 1.7 1 1 0 1 1 1 1 Tim44-like domain F-box-like PF12937.2 GAP91359.1 - 0.00068 19.3 0.3 0.0023 17.5 0.2 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAP91359.1 - 0.019 14.6 1.3 0.11 12.1 0.3 2.3 2 0 0 2 2 2 0 F-box domain SSF PF00474.12 GAP91360.1 - 4.5e-07 28.8 30.0 1.6e-06 27.0 20.7 1.8 1 1 0 1 1 1 1 Sodium:solute symporter family FMN_dh PF01070.13 GAP91361.1 - 1.7e-87 293.5 4.7 2.3e-48 164.8 0.6 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Glu_synthase PF01645.12 GAP91361.1 - 0.00034 19.6 0.0 0.00052 19.0 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 GAP91361.1 - 0.00042 19.3 0.1 0.0014 17.5 0.1 1.8 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 GAP91361.1 - 0.037 13.2 0.4 1.8 7.7 0.0 2.6 2 1 1 3 3 3 0 Histidine biosynthesis protein Peptidase_M26_N PF05342.9 GAP91361.1 - 0.052 12.5 0.0 0.079 11.9 0.0 1.2 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase N-terminal region DHO_dh PF01180.16 GAP91361.1 - 0.099 11.5 0.5 0.98 8.3 0.1 2.3 2 1 1 3 3 3 0 Dihydroorotate dehydrogenase CorA PF01544.13 GAP91362.1 - 0.0037 16.3 5.9 0.012 14.7 4.1 1.9 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein WAP PF00095.16 GAP91363.1 - 0.036 14.0 12.0 0.21 11.5 0.8 2.5 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Gamma-thionin PF00304.15 GAP91363.1 - 4.6 7.3 13.3 9.3 6.3 2.2 2.4 2 0 0 2 2 2 0 Gamma-thionin family Sdh_cyt PF01127.17 GAP91364.1 - 9.2e-16 57.7 3.1 1.2e-15 57.4 2.1 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF1546 PF07571.8 GAP91365.1 - 1.3e-25 89.3 0.0 2.7e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 GAP91365.1 - 1.4e-21 76.1 0.1 3.4e-21 74.9 0.1 1.7 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 GAP91365.1 - 0.0029 17.7 0.2 0.0054 16.8 0.1 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 GAP91365.1 - 0.05 13.3 0.1 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Bromodomain associated GATase_2 PF00310.16 GAP91366.1 - 4.9e-20 71.5 0.1 2.2e-15 56.2 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 GAP91366.1 - 5.8e-15 55.4 0.0 1.2e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 GAP91366.1 - 7.2e-14 51.6 0.0 1.3e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 GAP91366.1 - 3.7e-12 46.0 0.1 7.6e-12 45.0 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 GAP91366.1 - 3.9e-05 22.4 0.0 5.5e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II ADH_zinc_N PF00107.21 GAP91366.1 - 0.0016 17.9 0.4 1.1 8.8 0.0 3.4 3 0 0 3 3 3 1 Zinc-binding dehydrogenase GPCR_chapero_1 PF11904.3 GAP91367.1 - 0.94 8.5 4.6 1.4 7.9 3.2 1.3 1 0 0 1 1 1 0 GPCR-chaperone HsbA PF12296.3 GAP91369.1 - 2e-13 50.2 7.8 2e-13 50.2 5.4 1.7 2 0 0 2 2 2 1 Hydrophobic surface binding protein A GST_N_3 PF13417.1 GAP91370.1 - 1.4e-24 86.0 0.0 4.6e-24 84.4 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAP91370.1 - 2.4e-16 59.4 0.0 5.5e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAP91370.1 - 9.9e-09 34.9 1.4 9.9e-09 34.9 1.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAP91370.1 - 4.4e-06 26.7 0.0 0.034 14.3 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAP91370.1 - 0.0018 18.1 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CorA PF01544.13 GAP91371.1 - 1.2e-07 31.0 6.4 7.6e-07 28.4 4.5 2.2 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF676 PF05057.9 GAP91371.1 - 8.4e-05 21.9 0.0 0.00015 21.1 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 GAP91371.1 - 0.058 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein DUF3716 PF12511.3 GAP91372.1 - 1.4e-14 53.4 3.1 2.3e-14 52.7 2.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) MRI PF15325.1 GAP91372.1 - 0.087 13.8 1.6 2.3 9.2 0.0 2.4 2 0 0 2 2 2 0 Modulator of retrovirus infection TFIIA PF03153.8 GAP91372.1 - 0.52 10.1 9.3 0.66 9.8 6.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit p450 PF00067.17 GAP91373.1 - 1.5e-34 119.3 0.0 2.1e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L27 PF01016.14 GAP91374.1 - 2.1e-24 85.0 0.1 3.8e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein DUF3138 PF11336.3 GAP91374.1 - 0.14 10.3 0.8 0.2 9.7 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) IPP-2 PF04979.9 GAP91375.1 - 2.2e-12 47.3 9.2 2.2e-12 47.3 6.3 1.7 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Sigma70_ner PF04546.8 GAP91375.1 - 0.19 11.2 6.7 0.37 10.3 4.7 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Dicty_REP PF05086.7 GAP91375.1 - 3.3 5.3 7.5 4.3 4.9 5.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein UvdE PF03851.9 GAP91376.1 - 4.1e-116 386.8 0.0 5.4e-116 386.4 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE Adeno_terminal PF02459.10 GAP91376.1 - 0.48 8.5 2.6 0.78 7.8 1.8 1.3 1 0 0 1 1 1 0 Adenoviral DNA terminal protein SET PF00856.23 GAP91377.1 - 1.3e-15 58.1 0.0 2.5e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 GAP91377.1 - 0.0052 16.7 0.1 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding FAD_binding_1 PF00667.15 GAP91379.1 - 1.2e-38 132.7 0.0 1.7e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 GAP91379.1 - 1.6e-27 96.2 0.0 2.7e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 GAP91379.1 - 1.1e-19 71.0 0.0 9.5e-19 67.9 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain p450 PF00067.17 GAP91380.1 - 1.2e-64 218.5 0.0 1.6e-64 218.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Choline_sulf_C PF12411.3 GAP91380.1 - 0.017 14.9 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal Fungal_trans_2 PF11951.3 GAP91381.1 - 7.5e-10 37.9 0.0 1.2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP91381.1 - 1.9e-05 24.4 11.4 3.6e-05 23.5 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CppA_C PF14507.1 GAP91381.1 - 0.18 12.0 0.0 0.43 10.7 0.0 1.6 1 0 0 1 1 1 0 CppA C-terminal Sugar_tr PF00083.19 GAP91382.1 - 1.1e-97 327.5 30.9 1.2e-97 327.3 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP91382.1 - 1.9e-27 95.9 35.0 1.9e-27 95.9 24.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Colicin_im PF03857.8 GAP91382.1 - 0.91 9.2 5.2 0.25 11.1 0.4 2.1 2 0 0 2 2 2 0 Colicin immunity protein GFO_IDH_MocA PF01408.17 GAP91383.1 - 6.4e-25 88.0 0.2 9.8e-25 87.4 0.2 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 GAP91383.1 - 1.1e-06 28.3 0.1 3.3e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 GAP91383.1 - 0.0015 18.8 0.1 0.0029 17.9 0.1 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 GAP91383.1 - 0.025 14.4 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TRP PF06011.7 GAP91384.1 - 1.1e-26 93.4 29.4 3.3e-15 55.6 6.4 3.6 2 1 1 3 3 3 3 Transient receptor potential (TRP) ion channel Ank PF00023.25 GAP91387.1 - 6.3e-21 73.0 5.4 1e-11 44.0 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 GAP91387.1 - 1.9e-17 63.4 1.7 2e-12 47.2 0.0 2.3 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAP91387.1 - 8.2e-17 61.2 6.4 5.1e-09 36.4 0.1 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP91387.1 - 5.7e-13 47.7 3.6 5.8e-07 29.1 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 GAP91387.1 - 1.5e-12 47.3 5.5 2.8e-09 36.9 0.1 3.5 2 2 1 3 3 3 3 Ankyrin repeats (many copies) TP6A_N PF04406.9 GAP91388.1 - 1.2e-14 53.7 0.1 8.8e-09 34.9 0.0 2.6 2 0 0 2 2 2 2 Type IIB DNA topoisomerase DUF2399 PF09664.5 GAP91388.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) Prenyltrans PF00432.16 GAP91389.1 - 1e-24 85.7 5.5 1.6e-09 37.1 0.1 4.0 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 GAP91389.1 - 1.2e-23 83.2 0.6 7.6e-11 41.9 0.4 6.2 3 2 2 6 6 6 4 Prenyltransferase-like Prenyltrans_2 PF13249.1 GAP91389.1 - 1.9e-22 79.7 5.2 1.5e-14 54.3 0.7 4.8 4 2 0 4 4 4 3 Prenyltransferase-like Pec_lyase PF09492.5 GAP91389.1 - 8.3e-07 28.4 0.7 0.11 11.6 0.0 4.5 3 2 2 6 6 6 2 Pectic acid lyase A2M_comp PF07678.9 GAP91389.1 - 0.00027 20.2 0.3 0.0052 16.0 0.0 2.4 1 1 1 2 2 2 1 A-macroglobulin complement component Chromadorea_ALT PF05535.7 GAP91389.1 - 0.0067 16.4 1.7 0.012 15.7 0.2 2.1 2 0 0 2 2 2 1 Chromadorea ALT protein SGS PF05002.10 GAP91390.1 - 1.2e-29 101.8 5.1 3e-29 100.6 3.6 1.7 1 0 0 1 1 1 1 SGS domain CS PF04969.11 GAP91390.1 - 2.6e-09 37.4 0.0 4.7e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 GAP91390.1 - 2.6e-06 26.9 3.1 1.7e-05 24.4 0.9 2.5 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 GAP91390.1 - 0.0036 17.9 6.3 0.11 13.1 1.5 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAP91390.1 - 0.0091 15.8 3.9 7.9 6.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAP91390.1 - 1.6 9.5 5.5 29 5.6 0.4 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat p450 PF00067.17 GAP91391.1 - 1.3e-57 195.3 0.0 6.8e-57 193.0 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Shufflon_N PF04917.7 GAP91392.1 - 0.05 12.6 1.9 0.12 11.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial shufflon protein, N-terminal constant region EcsC PF12787.2 GAP91392.1 - 0.16 11.3 0.2 0.23 10.8 0.1 1.1 1 0 0 1 1 1 0 EcsC protein family Peptidase_S8 PF00082.17 GAP91393.1 - 9.3e-45 152.9 19.2 1.2e-44 152.6 13.3 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 GAP91393.1 - 0.0043 17.5 0.0 0.0089 16.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 SRP54 PF00448.17 GAP91394.1 - 2.6e-77 258.7 1.1 4.2e-77 258.0 0.8 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 GAP91394.1 - 7.8e-25 87.1 1.2 7.8e-25 87.1 0.9 4.3 3 1 2 5 5 4 1 Signal peptide binding domain SRP54_N PF02881.14 GAP91394.1 - 3.3e-12 46.3 0.2 8.8e-12 44.9 0.1 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 GAP91394.1 - 1.1e-08 34.7 0.1 2.7e-08 33.4 0.1 1.7 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 GAP91394.1 - 5.6e-08 32.7 0.0 1.6e-07 31.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain MobB PF03205.9 GAP91394.1 - 1.4e-05 24.8 0.0 3.3e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 GAP91394.1 - 2.1e-05 25.3 0.0 4.9e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 GAP91394.1 - 0.00012 21.6 0.1 0.00037 19.9 0.1 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 GAP91394.1 - 0.0007 18.4 0.7 0.004 15.9 0.5 2.2 1 1 0 1 1 1 1 ArgK protein AAA_31 PF13614.1 GAP91394.1 - 0.0011 18.9 0.0 0.35 10.7 0.0 2.7 1 1 0 2 2 2 1 AAA domain APS_kinase PF01583.15 GAP91394.1 - 0.0012 18.5 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.7 GAP91394.1 - 0.0018 17.4 0.0 0.0038 16.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 GAP91394.1 - 0.0018 18.3 0.0 0.0057 16.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAP91394.1 - 0.0022 17.9 0.1 0.0055 16.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 GAP91394.1 - 0.0033 17.7 0.0 0.0071 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 GAP91394.1 - 0.0039 16.7 0.1 0.04 13.4 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Thymidylate_kin PF02223.12 GAP91394.1 - 0.0045 16.3 0.1 0.017 14.4 0.0 2.1 2 0 0 2 2 1 1 Thymidylate kinase TrwB_AAD_bind PF10412.4 GAP91394.1 - 0.0046 15.6 0.6 0.021 13.4 0.0 2.1 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.18 GAP91394.1 - 0.0047 16.8 0.0 0.052 13.5 0.0 2.5 1 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 GAP91394.1 - 0.022 14.2 0.1 0.04 13.3 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain AAA_28 PF13521.1 GAP91394.1 - 0.024 14.6 0.3 0.051 13.5 0.2 1.7 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 GAP91394.1 - 0.028 13.6 1.0 2.3 7.4 0.6 2.9 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_19 PF13245.1 GAP91394.1 - 0.036 13.8 0.1 0.13 12.0 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain 6PF2K PF01591.13 GAP91394.1 - 0.038 13.0 0.0 0.062 12.3 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Arf PF00025.16 GAP91394.1 - 0.063 12.5 0.1 0.25 10.5 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA PF00004.24 GAP91394.1 - 0.067 13.3 0.3 0.28 11.3 0.2 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 GAP91394.1 - 0.093 13.0 0.4 0.3 11.3 0.0 2.1 2 1 0 2 2 2 0 ABC transporter PAP2 PF01569.16 GAP91396.1 - 2.8e-21 75.5 2.2 2.8e-21 75.5 1.5 2.2 1 1 1 2 2 2 1 PAP2 superfamily DUF983 PF06170.7 GAP91396.1 - 2.5 8.2 6.2 0.73 9.9 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Glyco_hydro_43 PF04616.9 GAP91397.1 - 9.5e-06 24.9 0.1 0.0013 17.8 0.0 2.8 1 1 2 3 3 3 3 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 GAP91397.1 - 5e-05 22.8 0.0 0.00011 21.7 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain HET PF06985.6 GAP91398.1 - 1.8e-26 92.9 0.0 4.3e-26 91.7 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_2 PF07719.12 GAP91400.1 - 4.9e-06 26.0 6.2 0.00058 19.5 1.4 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAP91400.1 - 9.9e-05 22.2 4.2 0.0063 16.4 0.7 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAP91400.1 - 0.00026 20.5 5.5 0.00045 19.8 3.8 1.3 1 0 0 1 1 1 1 TPR repeat TPR_14 PF13428.1 GAP91400.1 - 0.026 15.1 14.8 0.81 10.5 1.7 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAP91400.1 - 0.044 13.5 3.6 1 9.3 0.4 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAP91400.1 - 0.053 13.1 4.5 0.12 12.0 0.6 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAP91400.1 - 0.1 13.2 18.2 0.52 11.0 10.6 2.5 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 GAP91400.1 - 0.15 12.0 7.0 0.73 9.8 0.8 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Clr5 PF14420.1 GAP91401.1 - 7.3e-17 61.0 2.0 1.4e-16 60.1 1.4 1.5 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.1 GAP91401.1 - 1.4e-05 24.9 1.0 5.8e-05 22.9 0.7 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAP91401.1 - 0.00067 19.5 0.1 0.27 11.2 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Peptidase_M43 PF05572.8 GAP91404.1 - 2e-17 63.2 0.1 2.9e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 GAP91404.1 - 2.4e-07 30.9 0.9 5.7e-07 29.6 0.5 1.6 1 1 1 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 GAP91404.1 - 2e-05 25.1 0.5 2e-05 25.1 0.3 1.9 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 GAP91404.1 - 0.00074 19.6 1.6 0.0011 19.1 1.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like CVNH PF08881.5 GAP91405.1 - 5.1e-16 58.7 0.1 6.4e-16 58.4 0.1 1.2 1 0 0 1 1 1 1 CVNH domain zf-like PF04071.7 GAP91405.1 - 0.093 12.4 2.9 0.16 11.7 2.0 1.4 1 0 0 1 1 1 0 Cysteine-rich small domain Glyco_hyd_65N_2 PF14498.1 GAP91406.1 - 4.7e-45 154.1 0.0 9.4e-45 153.1 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.10 GAP91406.1 - 0.0021 16.7 0.1 0.0034 16.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain FTA2 PF13095.1 GAP91407.1 - 2e-21 76.5 0.0 3.2e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 UDPGT PF00201.13 GAP91408.1 - 0.0025 16.4 0.0 0.0037 15.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PBP PF01161.15 GAP91409.1 - 1.3e-10 41.2 0.1 3.1e-10 40.0 0.0 1.6 2 0 0 2 2 2 1 Phosphatidylethanolamine-binding protein Milton PF12448.3 GAP91409.1 - 0.055 13.6 6.5 0.12 12.5 4.5 1.6 1 1 0 1 1 1 0 Kinesin associated protein Ribosomal_L4 PF00573.17 GAP91410.1 - 8.3e-42 142.7 0.0 1.1e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family bZIP_1 PF00170.16 GAP91411.1 - 1.2e-10 41.1 2.6 1.8e-10 40.5 1.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAP91411.1 - 3e-06 26.9 1.1 5.3e-06 26.1 0.8 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 GAP91411.1 - 0.00034 20.8 3.7 0.00064 19.9 2.6 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Rep_fac-A_3 PF08661.6 GAP91412.1 - 6.5e-21 74.2 0.1 1.1e-20 73.5 0.1 1.4 1 0 0 1 1 1 1 Replication factor A protein 3 DUF1387 PF07139.6 GAP91412.1 - 0.38 10.3 6.2 0.57 9.7 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) GATA PF00320.22 GAP91413.1 - 4.7e-05 22.6 5.3 0.019 14.3 1.7 2.6 2 0 0 2 2 2 2 GATA zinc finger ECH_C PF13766.1 GAP91414.1 - 2.3e-31 108.4 0.0 4.6e-31 107.4 0.0 1.5 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 GAP91414.1 - 9.3e-25 87.1 0.1 5.2e-24 84.7 0.0 1.9 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family PqqD PF05402.7 GAP91414.1 - 0.041 13.8 0.1 0.88 9.6 0.0 2.4 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) LSM PF01423.17 GAP91415.1 - 3.6e-17 61.6 0.2 4.8e-17 61.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain Dak1 PF02733.12 GAP91416.1 - 2.1e-114 381.4 9.3 3e-114 380.9 6.4 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 GAP91416.1 - 8.7e-43 146.0 0.2 8.7e-43 146.0 0.1 1.8 2 0 0 2 2 2 1 DAK2 domain IF-2B PF01008.12 GAP91417.1 - 5e-47 160.2 0.0 1.5e-46 158.6 0.0 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family PAN_4 PF14295.1 GAP91419.1 - 1.4e-07 31.1 2.0 2.4e-07 30.3 1.4 1.4 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 GAP91419.1 - 3.6e-05 23.4 0.7 7.9e-05 22.3 0.5 1.5 1 0 0 1 1 1 1 PAN domain DUF3357 PF11837.3 GAP91419.1 - 0.059 13.2 1.4 0.28 11.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) PUCC PF03209.10 GAP91419.1 - 0.059 12.0 0.1 0.089 11.4 0.1 1.1 1 0 0 1 1 1 0 PUCC protein DUF95 PF01944.12 GAP91419.1 - 0.1 12.2 0.2 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF95 COMPASS-Shg1 PF05205.7 GAP91420.1 - 2.9e-25 88.6 0.7 2.9e-25 88.6 0.5 2.2 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 SPRY PF00622.23 GAP91421.1 - 1.5e-17 63.8 0.0 2.3e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Rod_cone_degen PF15201.1 GAP91421.1 - 1.1 9.1 4.3 7.3 6.5 0.1 2.9 3 0 0 3 3 3 0 Progressive rod-cone degeneration Acetyltransf_1 PF00583.19 GAP91425.1 - 7.3e-05 22.7 0.1 0.00015 21.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAP91425.1 - 0.00041 20.0 0.0 0.00082 19.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 GAP91425.1 - 0.00071 19.6 0.0 0.002 18.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAP91425.1 - 0.044 13.9 0.0 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain ABC2_membrane PF01061.19 GAP91426.1 - 1.1e-83 279.5 49.8 1.5e-47 161.4 16.1 3.9 3 1 1 4 4 4 3 ABC-2 type transporter ABC_tran PF00005.22 GAP91426.1 - 8.9e-29 100.5 0.0 4.3e-15 56.2 0.0 2.9 2 1 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 GAP91426.1 - 8.3e-14 51.1 10.6 1.3e-06 27.9 0.0 4.6 3 1 1 4 4 4 3 CDR ABC transporter ABC_trans_N PF14510.1 GAP91426.1 - 2.9e-10 40.0 0.6 0.00049 20.1 0.0 2.9 1 1 1 2 2 2 2 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 GAP91426.1 - 9.2e-10 38.2 0.0 2.6e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAP91426.1 - 3.5e-08 33.6 0.5 4.9e-06 26.6 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 GAP91426.1 - 4.3e-07 29.3 0.9 0.0011 18.4 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 GAP91426.1 - 1.4e-06 29.0 0.0 0.028 15.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 GAP91426.1 - 9.3e-06 25.5 0.0 0.032 14.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 GAP91426.1 - 3.8e-05 22.9 0.0 0.004 16.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 GAP91426.1 - 7.6e-05 22.2 0.6 0.0015 17.9 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 GAP91426.1 - 0.00014 21.5 0.0 0.057 13.0 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 GAP91426.1 - 0.00014 21.4 0.5 0.52 10.1 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain AAA_21 PF13304.1 GAP91426.1 - 0.00027 21.0 0.0 0.027 14.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAP91426.1 - 0.00027 21.2 0.0 0.045 14.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 GAP91426.1 - 0.0011 19.1 0.4 0.47 10.5 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 GAP91426.1 - 0.0013 18.9 0.0 1.7 8.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 GAP91426.1 - 0.0032 17.4 0.4 0.23 11.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.1 GAP91426.1 - 0.0062 16.8 0.5 0.18 12.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 GAP91426.1 - 0.023 14.3 0.6 1.3 8.7 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 GAP91426.1 - 0.025 13.9 0.1 6.1 6.2 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein SMC_N PF02463.14 GAP91426.1 - 0.035 13.3 0.0 14 4.8 0.0 3.6 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain Miro PF08477.8 GAP91426.1 - 0.043 14.3 0.0 17 5.9 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein AAA_14 PF13173.1 GAP91426.1 - 0.056 13.3 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 GAP91426.1 - 0.065 12.8 0.8 2.1 7.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 GAP91426.1 - 0.089 12.7 0.0 7.4 6.5 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.1 GAP91426.1 - 0.11 12.0 0.1 8.5 5.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 GAP91426.1 - 0.16 11.6 0.0 7.1 6.2 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase T2SE PF00437.15 GAP91426.1 - 0.18 10.6 0.2 4.7 6.0 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 GAP91426.1 - 0.22 10.9 2.0 8 5.7 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain OppC_N PF12911.2 GAP91426.1 - 1.6 8.1 6.2 4.4 6.7 0.1 3.1 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Glyco_hydro_30 PF02055.11 GAP91427.1 - 1.5e-39 135.5 2.4 3.7e-39 134.2 1.7 1.5 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 GAP91427.1 - 0.001 18.1 0.0 0.0039 16.1 0.0 1.8 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 Bac_surface_Ag PF01103.18 GAP91430.1 - 1.9e-36 126.1 0.1 3.1e-36 125.4 0.1 1.3 1 0 0 1 1 1 1 Surface antigen UQ_con PF00179.21 GAP91431.1 - 1.1e-26 92.9 0.1 1.5e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme E1-E2_ATPase PF00122.15 GAP91433.1 - 1.3e-60 204.3 2.9 1.3e-60 204.3 2.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAP91433.1 - 1.3e-31 109.5 3.9 1.3e-31 109.5 2.7 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAP91433.1 - 7.1e-28 98.4 0.0 1.6e-26 94.0 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAP91433.1 - 9.7e-16 57.0 0.1 3.2e-15 55.3 0.1 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 GAP91433.1 - 5.4e-15 55.1 0.0 1.1e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 GAP91433.1 - 1.9e-11 44.4 4.4 5.4e-11 43.0 3.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAP91433.1 - 3.9e-05 23.3 2.9 5e-05 23.0 0.9 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase eIF-1a PF01176.14 GAP91433.1 - 0.084 12.3 0.0 0.22 10.9 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Amidohydro_3 PF07969.6 GAP91434.1 - 7.2e-19 68.2 0.2 9.4e-19 67.9 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 GAP91434.1 - 5.3e-09 35.7 0.1 1.4e-08 34.4 0.1 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 GAP91434.1 - 0.018 15.0 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase Amidohydro_1 PF01979.15 GAP91434.1 - 0.02 14.5 0.2 0.054 13.1 0.1 1.9 1 1 0 1 1 1 0 Amidohydrolase family DUF4281 PF14108.1 GAP91434.1 - 0.079 13.0 0.0 0.32 11.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4281) Condensation PF00668.15 GAP91435.1 - 2.3e-05 23.3 0.0 3.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Condensation domain AATase PF07247.7 GAP91435.1 - 0.00073 18.2 0.0 0.00073 18.2 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase Chromo PF00385.19 GAP91437.1 - 1.6e-17 62.8 2.3 2.3e-08 33.5 0.3 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PBP1_TM PF14812.1 GAP91437.1 - 0.0064 16.7 15.0 0.4 11.0 3.6 3.0 2 0 0 2 2 2 2 Transmembrane domain of transglycosylase PBP1 at N-terminal BSP_II PF05432.6 GAP91437.1 - 0.0088 15.3 7.2 0.0088 15.3 5.0 2.3 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) Prothymosin PF03247.9 GAP91437.1 - 0.55 10.4 24.3 0.49 10.5 13.9 2.3 2 0 0 2 2 2 0 Prothymosin/parathymosin family Daxx PF03344.10 GAP91437.1 - 0.97 7.8 17.7 0.14 10.5 7.6 2.1 2 0 0 2 2 2 0 Daxx Family Spt5_N PF11942.3 GAP91437.1 - 0.99 10.0 25.1 0.46 11.1 12.9 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal TRAP_alpha PF03896.11 GAP91437.1 - 1.7 7.5 7.2 3.2 6.6 5.0 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Paf1 PF03985.8 GAP91437.1 - 1.8 7.2 11.1 0.35 9.5 5.3 1.6 2 0 0 2 2 2 0 Paf1 RNA_pol_Rpc4 PF05132.9 GAP91437.1 - 2.6 8.0 6.3 0.37 10.7 0.9 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 FAM176 PF14851.1 GAP91437.1 - 4.1 7.0 9.5 1.8 8.2 3.4 2.2 2 0 0 2 2 2 0 FAM176 family Sigma70_ner PF04546.8 GAP91437.1 - 5.2 6.6 17.9 2.7 7.5 7.2 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region VID27 PF08553.5 GAP91437.1 - 6.9 4.7 9.8 10 4.2 6.8 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Cu-oxidase_2 PF07731.9 GAP91438.1 - 6.9e-36 122.8 5.8 9.2e-36 122.3 0.2 2.9 3 1 1 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.17 GAP91438.1 - 1.8e-30 105.9 0.1 8.1e-30 103.8 0.0 2.1 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 GAP91438.1 - 3.6e-24 84.7 12.9 4.8e-14 52.1 0.1 3.9 4 1 1 5 5 5 2 Multicopper oxidase p450 PF00067.17 GAP91441.1 - 9.4e-55 185.9 0.0 1.3e-54 185.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.1 GAP91442.1 - 4.3e-78 262.7 38.9 5.6e-78 262.3 27.0 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAP91442.1 - 1.7e-19 69.5 29.7 2.6e-19 68.9 20.6 1.2 1 0 0 1 1 1 1 Amino acid permease AMP-binding PF00501.23 GAP91445.1 - 4e-75 252.7 0.0 9.4e-74 248.2 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 GAP91445.1 - 1.1e-09 39.1 0.1 3.8e-09 37.3 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 4HBT PF03061.17 GAP91446.1 - 9.3e-14 51.3 0.2 1.3e-13 50.8 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 GAP91446.1 - 0.015 15.3 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Herpes_BLLF1 PF05109.8 GAP91447.1 - 0.014 13.3 15.6 0.02 12.9 10.8 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) AstE_AspA PF04952.9 GAP91447.1 - 0.21 10.4 1.6 0.46 9.3 1.1 1.5 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Lsr2 PF11774.3 GAP91447.1 - 6.3 6.7 9.8 0.071 13.0 0.9 2.0 2 0 0 2 2 2 0 Lsr2 DUF4611 PF15387.1 GAP91449.1 - 3.1 8.0 6.8 8.2 6.6 2.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) GCR1_C PF12550.3 GAP91450.1 - 1.3e-22 79.4 1.9 2.1e-22 78.7 1.3 1.3 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Aminotran_1_2 PF00155.16 GAP91453.1 - 5.3e-39 134.1 0.0 7.3e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II RPN7 PF10602.4 GAP91454.1 - 3.4e-56 189.4 0.4 3.4e-56 189.4 0.3 1.6 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 GAP91454.1 - 2.2e-12 47.2 0.0 5e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_14 PF13428.1 GAP91454.1 - 0.065 13.8 0.2 0.51 11.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Pox_MCEL PF03291.11 GAP91455.1 - 1.6e-61 208.0 0.0 2.7e-43 148.1 0.0 2.9 1 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.7 GAP91455.1 - 1.9e-07 31.4 0.0 0.0091 16.4 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 GAP91455.1 - 7.4e-07 29.7 0.0 1.7e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP91455.1 - 1.8e-06 28.2 0.0 4.3e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP91455.1 - 3.1e-06 27.5 0.0 3e-05 24.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP91455.1 - 9.6e-06 25.2 0.0 0.00033 20.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP91455.1 - 1.1e-05 25.2 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 GAP91455.1 - 0.0011 18.0 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Raftlin PF15250.1 GAP91455.1 - 0.022 13.2 0.3 0.048 12.1 0.0 1.6 2 0 0 2 2 2 0 Raftlin Phytase-like PF13449.1 GAP91457.1 - 1.8e-26 93.2 0.0 3.3e-26 92.3 0.0 1.5 2 0 0 2 2 2 1 Esterase-like activity of phytase NHL PF01436.16 GAP91457.1 - 0.0052 16.6 0.2 0.041 13.8 0.1 2.5 2 0 0 2 2 2 1 NHL repeat CENP-P PF13096.1 GAP91458.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P Nrf1_activ_bdg PF10492.4 GAP91458.1 - 0.21 12.0 4.3 0.27 11.7 1.9 2.0 2 0 0 2 2 2 0 Nrf1 activator activation site binding domain DPM3 PF08285.6 GAP91459.1 - 6e-34 115.7 0.2 6.7e-34 115.6 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF3007 PF11460.3 GAP91459.1 - 0.041 13.9 0.0 0.047 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) Adeno_E3_14_5 PF04834.7 GAP91459.1 - 0.1 12.9 0.1 0.15 12.4 0.0 1.3 1 1 0 1 1 1 0 Early E3 14.5 kDa protein Fungal_trans PF04082.13 GAP91460.1 - 5.9e-09 35.1 0.0 1.3e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP91460.1 - 1.2e-07 31.5 11.3 2.5e-07 30.5 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4056 PF13265.1 GAP91460.1 - 0.055 12.4 0.0 0.096 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4056) DUF148 PF02520.12 GAP91460.1 - 0.12 12.1 0.3 0.31 10.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF148 FAD_binding_4 PF01565.18 GAP91461.1 - 8.9e-24 83.5 1.7 1.5e-23 82.8 1.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP91461.1 - 0.0044 16.9 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like HMG_box PF00505.14 GAP91462.1 - 2.5e-05 24.4 0.0 4.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 GAP91462.1 - 0.03 14.6 0.0 0.07 13.5 0.0 1.6 1 0 0 1 1 1 0 HMG-box domain DUF2413 PF10310.4 GAP91462.1 - 0.81 8.4 7.6 1.3 7.8 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Lipase_GDSL PF00657.17 GAP91463.1 - 5.4e-09 36.2 0.0 6.5e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase COX14 PF14880.1 GAP91464.1 - 1.5e-16 59.7 1.2 3.7e-16 58.4 0.1 2.1 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DUF3439 PF11921.3 GAP91464.1 - 0.34 10.6 7.7 0.74 9.5 5.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Med3 PF11593.3 GAP91464.1 - 4.3 6.4 21.5 1.4 8.0 3.3 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DUF1908 PF08926.6 GAP91465.1 - 0.086 11.5 0.0 0.15 10.8 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1908) Ribosomal_L13e PF01294.13 GAP91466.1 - 1.8e-61 206.7 3.7 2.3e-61 206.3 2.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Arm PF00514.18 GAP91467.1 - 4.1e-05 23.2 2.6 0.11 12.4 0.0 4.3 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat KAP PF05804.7 GAP91467.1 - 0.0014 16.7 0.0 0.0055 14.6 0.0 1.7 2 0 0 2 2 2 1 Kinesin-associated protein (KAP) TPR_10 PF13374.1 GAP91468.1 - 4e-76 249.0 22.3 7.1e-09 35.3 0.1 10.8 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.1 GAP91468.1 - 3.5e-58 193.4 33.6 5.8e-14 51.7 0.3 7.2 5 1 3 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 GAP91468.1 - 6e-33 110.0 4.5 0.097 12.6 0.0 11.3 12 0 0 12 12 12 9 Tetratricopeptide repeat TPR_14 PF13428.1 GAP91468.1 - 9.7e-31 103.4 30.7 0.0026 18.2 0.7 11.6 6 2 6 12 12 11 8 Tetratricopeptide repeat Apc3 PF12895.2 GAP91468.1 - 8.1e-22 77.1 21.4 0.00021 21.3 1.2 7.8 3 1 6 9 9 9 8 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 GAP91468.1 - 8.3e-21 72.6 3.2 1.4 8.6 0.0 10.8 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_20 PF14561.1 GAP91468.1 - 2.7e-20 72.2 40.0 0.012 15.7 0.2 9.2 1 1 8 9 9 9 8 Tetratricopeptide repeat Patatin PF01734.17 GAP91468.1 - 3e-20 73.0 0.0 9e-20 71.4 0.0 1.9 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_6 PF13174.1 GAP91468.1 - 3.2e-20 71.1 22.3 0.22 12.0 0.1 11.6 9 1 2 11 11 10 6 Tetratricopeptide repeat TPR_8 PF13181.1 GAP91468.1 - 4.4e-20 69.8 0.3 0.66 9.8 0.0 10.2 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.1 GAP91468.1 - 9.3e-20 70.7 31.2 0.00022 21.8 1.3 7.6 3 1 7 10 10 8 8 Tetratricopeptide repeat TPR_19 PF14559.1 GAP91468.1 - 2e-18 66.4 39.3 0.00074 19.8 0.0 8.1 2 1 7 9 9 9 8 Tetratricopeptide repeat TPR_7 PF13176.1 GAP91468.1 - 2.2e-18 64.5 21.8 0.1 12.4 0.0 10.9 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_17 PF13431.1 GAP91468.1 - 5.1e-18 63.7 17.7 0.46 10.8 0.1 9.4 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.1 GAP91468.1 - 1.4e-15 56.6 13.6 0.01 15.4 0.1 7.1 3 1 8 11 11 11 8 TPR repeat PPR PF01535.15 GAP91468.1 - 5.5e-13 47.9 0.0 12 6.1 0.0 9.5 9 0 0 9 9 9 0 PPR repeat TPR_4 PF07721.9 GAP91468.1 - 1.2e-10 40.7 51.8 0.18 12.3 0.8 10.4 11 0 0 11 11 9 4 Tetratricopeptide repeat NB-ARC PF00931.17 GAP91468.1 - 1.1e-09 37.5 0.0 2.6e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain Cas_DxTHG PF09455.5 GAP91468.1 - 1.4e-08 34.3 0.3 0.022 13.8 0.0 3.9 1 1 0 3 3 3 2 CRISPR-associated (Cas) DxTHG family PPR_1 PF12854.2 GAP91468.1 - 9.4e-05 21.8 21.7 7.8 6.0 0.1 9.1 9 0 0 9 9 9 0 PPR repeat NACHT PF05729.7 GAP91468.1 - 0.00017 21.3 0.0 0.00049 19.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 GAP91468.1 - 0.1 12.5 0.0 0.65 9.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain TPR_3 PF07720.7 GAP91468.1 - 0.16 11.8 36.2 6.8 6.6 0.3 8.2 9 0 0 9 9 8 0 Tetratricopeptide repeat Clathrin PF00637.15 GAP91468.1 - 0.37 10.3 11.5 4.4 6.8 0.8 5.6 2 2 5 7 7 7 0 Region in Clathrin and VPS DUF3301 PF11743.3 GAP91468.1 - 0.43 10.1 13.2 6.5 6.3 0.1 5.5 2 2 2 5 5 5 0 Protein of unknown function (DUF3301) Lipase_GDSL_2 PF13472.1 GAP91470.1 - 5e-17 62.5 2.1 5e-17 62.5 1.4 1.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAP91470.1 - 4.4e-11 43.0 0.3 9.9e-11 41.9 0.2 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DAHP_synth_1 PF00793.15 GAP91471.1 - 2.2e-98 328.3 0.1 2.5e-98 328.0 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family K_channel_TID PF07941.6 GAP91472.1 - 0.031 14.4 12.6 0.061 13.5 8.8 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain zf-P11 PF03854.9 GAP91472.1 - 0.13 11.7 4.6 0.21 11.1 3.2 1.3 1 0 0 1 1 1 0 P-11 zinc finger Ribosomal_60s PF00428.14 GAP91472.1 - 0.63 10.4 6.1 1.2 9.5 4.2 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Ribosomal_L50 PF10501.4 GAP91473.1 - 3.7e-15 55.8 0.0 6.8e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal subunit 39S DUF605 PF04652.11 GAP91473.1 - 5.1 6.3 13.0 7.9 5.7 8.6 1.6 2 0 0 2 2 2 0 Vta1 like 4HBT PF03061.17 GAP91474.1 - 3.5e-05 23.8 0.5 0.0034 17.4 0.0 2.5 2 0 0 2 2 2 2 Thioesterase superfamily MFS_1 PF07690.11 GAP91475.1 - 1.4e-36 125.9 53.5 3.1e-36 124.8 35.6 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAP91475.1 - 3.4e-08 32.1 15.7 6.8e-08 31.1 10.9 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 GAP91475.1 - 1.5 6.7 10.0 0.025 12.6 1.2 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family NmrA PF05368.8 GAP91476.1 - 1.2e-30 106.4 0.0 1.4e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAP91476.1 - 4.4e-16 59.4 0.0 6.3e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAP91476.1 - 0.0017 17.8 0.0 0.0049 16.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 GAP91476.1 - 0.039 14.2 0.0 0.099 12.9 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 GAP91476.1 - 0.082 11.5 0.0 0.19 10.4 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Sec3_C_2 PF15278.1 GAP91476.1 - 0.088 12.9 0.6 2.4 8.3 0.4 2.9 2 1 0 2 2 2 0 Sec3 exocyst complex subunit p450 PF00067.17 GAP91477.1 - 7.8e-25 87.3 0.0 1.7e-24 86.2 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.13 GAP91478.1 - 7.1e-26 90.8 0.0 1e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase DUF977 PF06163.6 GAP91478.1 - 0.023 14.4 0.0 0.056 13.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) Methyltransf_2 PF00891.13 GAP91479.1 - 3e-30 105.1 0.0 4.1e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 GAP91479.1 - 0.0016 18.9 0.1 0.0074 16.8 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain CheR PF01739.13 GAP91479.1 - 0.012 14.9 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain AMP-binding PF00501.23 GAP91480.1 - 8.1e-53 179.2 0.0 1.2e-52 178.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 GAP91480.1 - 1.5e-26 94.0 0.1 9e-26 91.5 0.1 2.1 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 GAP91480.1 - 1.4e-07 31.6 0.0 3.7e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 GAP91480.1 - 1.8e-06 28.0 1.2 3.5e-06 27.0 0.9 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP91480.1 - 0.00024 20.9 0.0 0.00063 19.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family GH3 PF03321.8 GAP91480.1 - 0.32 9.4 0.1 0.86 8.0 0.0 1.6 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Aminotran_1_2 PF00155.16 GAP91481.1 - 1.7e-37 129.2 0.0 1.8e-31 109.4 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Fungal_trans PF04082.13 GAP91483.1 - 1.1e-06 27.7 0.0 2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP91483.1 - 2.1e-05 24.3 9.4 3.7e-05 23.5 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAF1_ABF1 PF04684.8 GAP91483.1 - 0.49 9.1 19.6 0.94 8.2 13.6 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Cyclase PF04199.8 GAP91484.1 - 3.8e-16 59.2 0.4 5.4e-16 58.7 0.3 1.2 1 0 0 1 1 1 1 Putative cyclase Pyr_redox_3 PF13738.1 GAP91485.1 - 6.2e-24 85.1 0.0 2.1e-23 83.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP91485.1 - 4.9e-06 26.4 0.3 3.8e-05 23.6 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 GAP91485.1 - 0.0062 14.7 0.0 0.011 13.9 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 GAP91485.1 - 0.018 14.7 0.4 0.052 13.3 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 GAP91485.1 - 0.02 14.8 0.1 17 5.2 0.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 GAP91485.1 - 0.043 13.9 0.3 0.23 11.5 0.0 2.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 GAP91485.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.20 GAP91486.1 - 6.4e-09 35.9 0.0 1.3e-08 34.9 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAP91486.1 - 0.0028 17.3 0.0 0.0041 16.8 0.0 1.2 1 0 0 1 1 1 1 KR domain GSDH PF07995.6 GAP91487.1 - 5.9e-119 397.0 0.1 6.9e-119 396.7 0.0 1.0 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase NHL PF01436.16 GAP91487.1 - 0.00034 20.4 0.0 0.13 12.3 0.0 3.7 4 0 0 4 4 4 1 NHL repeat Reg_prop PF07494.6 GAP91487.1 - 0.0014 18.3 2.4 4.4 7.6 0.0 4.0 3 0 0 3 3 3 2 Two component regulator propeller WW PF00397.21 GAP91488.1 - 2.5e-06 27.2 4.8 1.9e-05 24.3 4.1 1.9 2 0 0 2 2 2 1 WW domain Peptidase_C14 PF00656.17 GAP91489.1 - 4.3e-68 229.6 0.0 6.3e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 Caspase domain DnaJ PF00226.26 GAP91492.1 - 1.3e-11 44.0 0.7 6.1e-11 41.8 0.5 2.2 1 1 0 1 1 1 1 DnaJ domain Sugar_tr PF00083.19 GAP91493.1 - 2.3e-68 230.8 21.4 2.6e-68 230.6 14.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP91493.1 - 8.6e-19 67.4 34.2 1.5e-18 66.6 20.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidohydro_3 PF07969.6 GAP91494.1 - 2e-22 79.9 9.3 3.2e-15 56.2 3.8 2.9 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 GAP91494.1 - 1.4e-11 44.0 0.0 3.5e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase DUF3328 PF11807.3 GAP91495.1 - 2e-26 93.0 0.1 2.6e-26 92.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3399 PF11879.3 GAP91495.1 - 0.55 10.4 2.0 24 5.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3399) Acetyltransf_1 PF00583.19 GAP91497.1 - 0.00023 21.1 0.2 0.00049 20.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAP91497.1 - 0.002 18.2 0.0 0.0059 16.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAP91497.1 - 0.028 14.5 0.0 0.055 13.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain YkuI_C PF10388.4 GAP91497.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 EAL-domain associated signalling protein domain Pyr_redox_2 PF07992.9 GAP91498.1 - 1.7e-21 77.0 0.1 2.1e-21 76.7 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAP91498.1 - 2.9e-07 29.6 0.1 3e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 GAP91498.1 - 3.8e-07 30.0 0.0 0.014 15.1 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.9 GAP91498.1 - 7.9e-07 27.8 0.2 9.4e-05 21.0 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 GAP91498.1 - 8.4e-05 22.5 0.0 0.0002 21.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 GAP91498.1 - 0.0002 20.5 0.1 0.00064 18.8 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 GAP91498.1 - 0.00055 18.9 0.1 0.0012 17.8 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAP91498.1 - 0.0013 18.8 0.1 0.046 13.7 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAP91498.1 - 0.0015 17.6 0.0 0.0049 15.9 0.1 1.8 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 GAP91498.1 - 0.0035 16.2 4.4 0.0099 14.7 0.9 2.4 2 1 1 3 3 3 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 GAP91498.1 - 0.0042 15.7 0.2 0.0069 15.0 0.1 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Amino_oxidase PF01593.19 GAP91498.1 - 0.0054 15.8 2.1 0.012 14.7 0.1 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase UDPG_MGDP_dh_N PF03721.9 GAP91498.1 - 0.024 14.0 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.2 GAP91498.1 - 0.032 13.3 0.6 0.032 13.3 0.4 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAP91498.1 - 0.041 12.7 0.0 0.075 11.9 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 GAP91498.1 - 0.068 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Cytochrom_C PF00034.16 GAP91498.1 - 0.074 13.8 0.0 0.64 10.8 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c AlaDh_PNT_C PF01262.16 GAP91498.1 - 0.085 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 GAP91498.1 - 0.15 12.4 0.1 0.79 10.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 GAP91499.1 - 2.1e-37 128.7 54.3 2.1e-37 128.7 37.6 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP91499.1 - 3.6e-07 29.1 36.9 0.0001 21.0 8.3 3.1 3 1 1 4 4 4 2 Sugar (and other) transporter MerB PF03243.10 GAP91500.1 - 2.1e-27 95.5 0.0 3.7e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 Alkylmercury lyase LexA_DNA_bind PF01726.11 GAP91500.1 - 0.038 13.5 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 LexA DNA binding domain DDRGK PF09756.4 GAP91500.1 - 0.057 12.8 0.0 0.082 12.3 0.0 1.1 1 0 0 1 1 1 0 DDRGK domain HTH_20 PF12840.2 GAP91500.1 - 0.082 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r3 PF04539.11 GAP91500.1 - 0.083 12.7 0.0 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 Sigma-70 region 3 HMGL-like PF00682.14 GAP91501.1 - 2.2e-56 191.1 0.0 4.3e-56 190.2 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Ank_2 PF12796.2 GAP91502.1 - 2.5e-43 146.3 8.1 1.5e-16 60.5 1.0 4.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAP91502.1 - 7.2e-36 120.2 12.3 1.1e-06 28.1 0.0 8.6 7 1 1 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 GAP91502.1 - 8.2e-27 93.0 6.3 5.1e-07 30.0 0.0 6.7 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP91502.1 - 2.2e-24 84.9 7.0 1.4e-06 28.3 0.8 6.0 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP91502.1 - 7.7e-21 72.1 11.7 0.00062 19.7 0.3 7.9 8 0 0 8 8 8 5 Ankyrin repeat AAA_29 PF13555.1 GAP91502.1 - 0.024 14.1 0.0 0.095 12.2 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 GAP91502.1 - 0.039 13.7 0.0 0.13 12.0 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 GAP91502.1 - 0.05 13.2 0.6 0.4 10.3 0.4 2.2 1 1 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 GAP91502.1 - 0.071 13.2 0.0 0.29 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain CRIC_ras_sig PF10534.4 GAP91502.1 - 0.086 12.9 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Connector enhancer of kinase suppressor of ras MFS_1 PF07690.11 GAP91503.1 - 1.5e-40 138.9 55.2 1.5e-40 138.9 38.3 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAP91503.1 - 6.9e-14 50.9 24.6 2.1e-13 49.3 17.1 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Endosulfine PF04667.12 GAP91504.1 - 0.027 14.4 0.1 0.061 13.2 0.1 1.5 1 0 0 1 1 1 0 cAMP-regulated phosphoprotein/endosulfine conserved region TPR_11 PF13414.1 GAP91504.1 - 0.067 12.8 0.3 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 TPR repeat Toxin_7 PF05980.7 GAP91505.1 - 1.5 8.9 11.2 0.11 12.5 3.9 1.8 2 0 0 2 2 2 0 Toxin 7 Pectate_lyase_3 PF12708.2 GAP91507.1 - 5.1e-54 183.7 18.0 2.4e-46 158.6 2.3 3.9 2 2 1 3 3 3 2 Pectate lyase superfamily protein Peptidase_S8 PF00082.17 GAP91507.1 - 1.1e-17 64.0 0.8 2.7e-17 62.8 0.1 2.1 2 0 0 2 2 2 1 Subtilase family DUF4419 PF14388.1 GAP91508.1 - 9.5e-105 350.0 0.0 1.2e-104 349.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) HET PF06985.6 GAP91509.1 - 2.8e-22 79.3 0.0 4.8e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Secretin_N_2 PF07655.8 GAP91510.1 - 0.34 11.3 10.9 0.58 10.5 7.5 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain NDUF_B8 PF05821.6 GAP91512.1 - 1.7e-06 27.8 0.0 2.4e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.18 GAP91513.1 - 3.2e-72 242.8 0.4 4.6e-72 242.3 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAP91513.1 - 2.3e-14 53.0 0.1 7.3e-14 51.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAP91513.1 - 1.3e-08 34.8 0.0 4e-08 33.3 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSA PF07529.8 GAP91513.1 - 0.0018 18.0 8.0 0.0018 18.0 5.6 2.5 1 1 1 2 2 2 1 HSA HDA2-3 PF11496.3 GAP91513.1 - 0.0076 15.0 0.0 3.9 6.1 0.0 2.5 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 DEAD_2 PF06733.10 GAP91513.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 DUF3500 PF12006.3 GAP91514.1 - 4.1e-98 328.1 0.0 4.7e-98 327.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) ELMO_CED12 PF04727.8 GAP91516.1 - 0.043 13.3 0.0 0.085 12.3 0.0 1.5 1 0 0 1 1 1 0 ELMO/CED-12 family PA14 PF07691.7 GAP91517.1 - 0.077 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 PA14 domain F-box-like PF12937.2 GAP91518.1 - 0.0009 18.9 0.2 0.0022 17.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAP91518.1 - 0.029 14.0 0.2 0.068 12.8 0.1 1.7 1 0 0 1 1 1 0 F-box domain SpvB PF03534.8 GAP91519.1 - 4.5e-71 239.2 1.2 7.1e-71 238.6 0.0 1.9 2 0 0 2 2 2 1 Salmonella virulence plasmid 65kDa B protein TcdB_toxin_midN PF12256.3 GAP91519.1 - 2.1e-35 121.7 1.8 3e-29 101.7 0.0 5.4 2 1 3 5 5 5 3 Insecticide toxin TcdB middle/N-terminal region TcdB_toxin_midC PF12255.3 GAP91519.1 - 1e-19 70.6 0.2 2.3e-19 69.4 0.2 1.6 1 0 0 1 1 1 1 Insecticide toxin TcdB middle/C-terminal region VCBS PF13517.1 GAP91519.1 - 1.6e-06 28.4 9.6 0.00029 21.1 0.1 4.9 3 1 1 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 GAP91519.1 - 6.1 6.6 13.5 0.72 9.6 0.1 4.2 5 0 0 5 5 5 0 FG-GAP repeat adh_short PF00106.20 GAP91520.1 - 4.4e-18 65.7 0.1 1.1e-17 64.4 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP91520.1 - 3e-06 27.1 0.0 1.3e-05 25.0 0.0 2.0 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP91520.1 - 1.8e-05 24.4 0.1 6.4e-05 22.6 0.1 1.9 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 GAP91520.1 - 0.027 14.2 0.5 0.05 13.3 0.4 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 GAP91520.1 - 0.03 13.7 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 GAP91520.1 - 0.044 12.8 0.0 0.075 12.0 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 GAP91520.1 - 0.22 11.5 0.8 0.38 10.7 0.3 1.6 2 0 0 2 2 2 0 NADH(P)-binding Cytochrom_B_N PF00033.14 GAP91521.1 - 0.0044 16.3 0.5 0.021 14.1 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB DUF4405 PF14358.1 GAP91521.1 - 0.0083 16.2 2.0 0.024 14.7 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4405) DUF308 PF03729.8 GAP91521.1 - 0.059 13.3 18.3 0.28 11.2 2.9 3.4 3 1 0 3 3 3 0 Short repeat of unknown function (DUF308) Peptidase_S8 PF00082.17 GAP91522.1 - 0.00012 21.3 5.7 0.00062 19.0 0.7 2.5 2 1 1 3 3 3 2 Subtilase family Pkinase_Tyr PF07714.12 GAP91522.1 - 0.054 12.5 0.0 2.9 6.9 0.0 2.8 3 0 0 3 3 3 0 Protein tyrosine kinase Patatin PF01734.17 GAP91522.1 - 0.12 12.2 1.3 1.1 9.1 0.0 2.7 3 0 0 3 3 3 0 Patatin-like phospholipase BTB PF00651.26 GAP91524.1 - 1e-08 35.1 0.0 1.8e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain NACHT PF05729.7 GAP91526.1 - 2.8e-09 36.8 0.0 8.3e-09 35.3 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAP91526.1 - 0.0064 16.6 0.0 0.039 14.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 GAP91526.1 - 0.0075 15.7 0.0 0.066 12.6 0.0 2.4 3 0 0 3 3 3 1 AAA-like domain AAA_29 PF13555.1 GAP91526.1 - 0.034 13.6 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 GAP91526.1 - 0.049 13.9 0.1 0.24 11.6 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 GAP91526.1 - 0.056 13.4 0.0 0.63 9.9 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_30 PF13604.1 GAP91526.1 - 0.1 12.1 0.0 0.37 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 GAP91526.1 - 0.15 11.7 0.0 0.76 9.5 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 GAP91527.1 - 6.5e-08 32.3 0.0 2.1e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAP91527.1 - 2e-05 24.7 0.0 0.0001 22.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAP91527.1 - 0.0024 17.8 0.2 0.009 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 GAP91527.1 - 0.0042 17.9 0.0 0.049 14.4 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 GAP91527.1 - 0.03 14.1 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 GAP91527.1 - 0.051 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.17 GAP91527.1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.1 GAP91527.1 - 1 9.6 3.4 6.3 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain ubiquitin PF00240.18 GAP91530.1 - 5.4e-18 64.1 0.2 2.9e-13 49.0 0.2 2.8 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 GAP91530.1 - 1.3e-05 24.7 1.7 0.001 18.6 0.2 3.6 4 0 0 4 4 4 1 Ubiquitin-2 like Rad60 SUMO-like PGAP1 PF07819.8 GAP91530.1 - 0.00011 21.8 0.0 0.00023 20.8 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 GAP91530.1 - 0.00064 19.0 0.0 0.0014 17.9 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 GAP91530.1 - 0.0046 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ubiquitin_2 PF14560.1 GAP91530.1 - 0.012 15.8 0.4 0.89 9.8 0.2 2.6 2 0 0 2 2 2 0 Ubiquitin-like domain DUF829 PF05705.9 GAP91530.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) FmdA_AmdA PF03069.10 GAP91531.1 - 3.8e-42 144.3 0.0 2.5e-24 85.6 0.0 3.1 1 1 1 2 2 2 2 Acetamidase/Formamidase family Glyco_hydro_61 PF03443.9 GAP91532.1 - 4.2e-41 141.1 0.1 5.4e-41 140.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 GRAM PF02893.15 GAP91535.1 - 1.7e-25 88.3 0.5 7.2e-13 47.8 0.0 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.15 GAP91535.1 - 2.4e-24 85.6 0.0 4.5e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 GAP91535.1 - 1.2e-12 47.9 0.0 4.4e-12 46.1 0.0 2.1 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 GAP91535.1 - 1.5e-05 24.9 0.1 0.00028 20.9 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 GAP91535.1 - 0.00054 20.1 0.0 0.0015 18.7 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain UDPGT PF00201.13 GAP91535.1 - 0.00068 18.2 0.0 0.0011 17.5 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_6 PF15406.1 GAP91535.1 - 0.033 14.2 0.2 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain PH_3 PF14593.1 GAP91535.1 - 0.04 13.7 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 PH domain Helicase_C_2 PF13307.1 GAP91536.1 - 3.4e-59 199.5 0.0 7.9e-59 198.3 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 GAP91536.1 - 5.3e-46 156.1 0.0 8.9e-46 155.4 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.10 GAP91536.1 - 0.01 15.7 0.0 0.81 9.4 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 GAP91536.1 - 0.042 13.3 0.5 0.44 10.0 0.3 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase TMEM51 PF15345.1 GAP91536.1 - 0.074 12.7 0.5 0.14 11.8 0.3 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 NIF PF03031.13 GAP91537.1 - 2.2e-27 95.6 0.0 5.7e-27 94.3 0.0 1.7 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 GAP91537.1 - 1.4e-08 34.4 0.0 2.5e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 GAP91537.1 - 3.8e-05 23.7 0.0 0.00012 22.0 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl PF00364.17 GAP91537.1 - 0.0065 16.0 0.1 0.44 10.2 0.2 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 GAP91537.1 - 0.076 12.7 0.3 0.26 10.9 0.2 2.0 1 0 0 1 1 1 0 Biotin-lipoyl like Astro_capsid PF03115.9 GAP91537.1 - 0.31 9.2 1.4 0.53 8.4 1.0 1.3 1 0 0 1 1 1 0 Astrovirus capsid protein precursor BUD22 PF09073.5 GAP91537.1 - 4 6.4 23.0 1.8 7.5 12.8 2.1 2 0 0 2 2 2 0 BUD22 DUF3176 PF11374.3 GAP91538.1 - 0.0084 15.9 2.7 0.0084 15.9 1.9 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) GRIM-19 PF06212.7 GAP91539.1 - 4.1e-22 78.2 0.1 6.9e-22 77.5 0.0 1.4 1 1 0 1 1 1 1 GRIM-19 protein Asp PF00026.18 GAP91540.1 - 2.1e-74 250.6 9.0 2.4e-74 250.4 6.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAP91540.1 - 1.1e-07 31.9 2.4 3.9e-07 30.1 0.4 2.6 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 GAP91540.1 - 0.00028 20.4 0.0 0.053 13.0 0.0 2.9 2 1 0 2 2 2 2 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 GAP91540.1 - 0.00086 19.7 1.3 0.015 15.7 0.3 2.8 2 1 0 2 2 2 1 Aspartyl protease Peptidase_S10 PF00450.17 GAP91541.1 - 1.6e-39 136.3 0.0 1.1e-38 133.4 0.0 2.1 1 1 0 1 1 1 1 Serine carboxypeptidase Glyco_hydro_28 PF00295.12 GAP91542.1 - 5.7e-29 101.0 4.2 8.1e-29 100.6 2.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 GAP91542.1 - 0.099 12.3 21.3 0.018 14.7 6.2 2.9 1 1 1 2 2 2 0 Right handed beta helix region TENA_THI-4 PF03070.11 GAP91543.1 - 4.2e-06 26.6 2.3 1.4e-05 24.9 1.6 1.8 1 1 0 1 1 1 1 TENA/THI-4/PQQC family Isochorismatase PF00857.15 GAP91544.1 - 5.4e-20 72.0 0.0 8.3e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Na_H_Exchanger PF00999.16 GAP91545.1 - 3.1e-29 101.6 9.3 3.6e-29 101.4 6.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Glyco_transf_90 PF05686.7 GAP91546.1 - 1.6e-19 69.9 4.7 9.5e-16 57.4 0.3 2.7 3 0 0 3 3 3 2 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 GAP91546.1 - 0.14 12.4 0.5 0.82 9.9 0.0 2.4 3 0 0 3 3 3 0 Glycosyl transferases group 1 HET PF06985.6 GAP91549.1 - 5.2e-20 72.0 0.0 1.5e-19 70.5 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1768 PF08719.6 GAP91551.1 - 7.2e-11 42.0 0.0 1.1e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) HET PF06985.6 GAP91553.1 - 7.8e-21 74.6 0.0 1.3e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Mito_carr PF00153.22 GAP91554.1 - 7.3e-49 163.4 6.7 2.3e-17 62.4 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein FHIPEP PF00771.15 GAP91554.1 - 0.022 13.1 0.3 0.031 12.6 0.2 1.1 1 0 0 1 1 1 0 FHIPEP family Ank_2 PF12796.2 GAP91555.1 - 2e-38 130.6 0.2 2e-16 60.0 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAP91555.1 - 1.1e-32 110.2 0.0 0.00018 21.1 0.0 6.7 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 GAP91555.1 - 7.1e-24 83.3 0.0 1.2e-05 25.3 0.0 5.9 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAP91555.1 - 7.4e-23 80.4 0.0 2.4e-06 27.8 0.0 4.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP91555.1 - 2.8e-15 54.9 0.0 0.072 13.3 0.0 6.9 6 0 0 6 6 6 5 Ankyrin repeat NACHT PF05729.7 GAP91555.1 - 3.8e-05 23.4 0.0 0.00011 21.8 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAP91555.1 - 0.0021 18.2 2.6 0.012 15.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 GAP91555.1 - 0.0042 17.0 1.6 0.035 14.0 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain FAD_binding_4 PF01565.18 GAP91556.1 - 4.2e-28 97.5 5.6 6.7e-28 96.8 3.9 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP91556.1 - 1.2e-10 41.0 0.0 2.8e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like EI24 PF07264.6 GAP91557.1 - 9.9e-06 25.1 17.6 7.2e-05 22.3 12.1 2.1 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF2417 PF10329.4 GAP91557.1 - 0.11 11.9 4.9 0.12 11.8 2.0 1.9 2 0 0 2 2 2 0 Region of unknown function (DUF2417) DUF4231 PF14015.1 GAP91557.1 - 1.9 8.4 4.5 2.1 8.3 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) ADH_N PF08240.7 GAP91559.1 - 1.7e-28 98.5 0.2 3.3e-28 97.6 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Acetyltransf_1 PF00583.19 GAP91559.1 - 5.3e-14 52.0 0.2 1.3e-13 50.7 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family ADH_zinc_N PF00107.21 GAP91559.1 - 8e-09 35.1 0.5 2e-08 33.8 0.3 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 GAP91559.1 - 5.7e-08 32.2 0.8 1.7e-07 30.7 0.5 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Acetyltransf_7 PF13508.1 GAP91559.1 - 1.2e-07 31.7 0.1 2.1e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAP91559.1 - 8.1e-07 29.2 0.0 1.2e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAP91559.1 - 6.9e-06 26.0 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAP91559.1 - 2e-05 24.7 0.1 3.9e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAP91559.1 - 3.8e-05 23.3 0.0 8.5e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 GAP91559.1 - 0.0003 20.6 0.0 0.00067 19.4 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 GAP91559.1 - 0.003 17.4 0.0 0.005 16.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAP91559.1 - 0.0036 17.1 0.0 0.0058 16.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HI0933_like PF03486.9 GAP91559.1 - 0.0067 14.9 0.2 0.012 14.1 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 GAP91559.1 - 0.077 11.8 0.3 0.13 11.1 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 GAP91559.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NUDIX PF00293.23 GAP91560.1 - 0.075 12.6 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 NUDIX domain CPSase_L_D2 PF02786.12 GAP91561.1 - 3.5e-58 196.3 0.1 5.1e-58 195.8 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 GAP91561.1 - 1.5e-29 102.1 0.0 4.4e-29 100.5 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 GAP91561.1 - 5e-25 87.7 0.0 3.5e-24 85.0 0.0 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 GAP91561.1 - 3.2e-13 49.8 0.1 5.9e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 GAP91561.1 - 2.5e-12 46.2 0.8 8e-12 44.6 0.2 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 GAP91561.1 - 6e-12 44.9 0.0 6.2e-07 28.4 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 GAP91561.1 - 5.8e-09 35.6 0.0 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 GAP91561.1 - 2.7e-05 23.5 0.0 5.1e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 GAP91561.1 - 2.8e-05 23.6 0.4 7.9e-05 22.2 0.3 1.7 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp_3 PF02655.9 GAP91561.1 - 0.00029 20.7 0.0 0.00071 19.4 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 GAP91561.1 - 0.0032 16.9 0.0 0.013 14.9 0.0 1.9 2 0 0 2 2 2 1 RimK-like ATP-grasp domain HlyD_3 PF13437.1 GAP91561.1 - 0.012 15.8 0.1 0.061 13.6 0.1 2.2 2 0 0 2 2 2 0 HlyD family secretion protein RnfC_N PF13375.1 GAP91561.1 - 0.026 14.2 0.1 0.07 12.8 0.1 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain HlyD PF00529.15 GAP91561.1 - 0.059 12.6 0.4 0.12 11.7 0.2 1.4 1 0 0 1 1 1 0 HlyD family secretion protein HlyD_2 PF12700.2 GAP91561.1 - 0.082 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 HlyD family secretion protein ATPgrasp_YheCD PF14398.1 GAP91561.1 - 0.16 10.7 0.0 0.28 9.9 0.0 1.3 1 0 0 1 1 1 0 YheC/D like ATP-grasp Carboxyl_trans PF01039.17 GAP91562.1 - 1.1e-83 281.3 0.0 1.4e-83 280.9 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain FAD_binding_2 PF00890.19 GAP91563.1 - 8.3e-48 163.2 2.9 6.4e-38 130.6 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 GAP91563.1 - 7.3e-11 41.7 0.0 1.5e-10 40.7 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 GAP91563.1 - 4.8e-09 35.5 0.9 4.8e-09 35.5 0.6 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 GAP91563.1 - 7.9e-07 28.2 1.1 7.9e-07 28.2 0.8 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 GAP91563.1 - 1.5e-06 27.0 0.5 1.5e-06 27.0 0.3 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 GAP91563.1 - 2.3e-06 27.6 0.8 5.2e-06 26.4 0.5 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP91563.1 - 2e-05 24.5 0.8 6.7e-05 22.8 0.5 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 GAP91563.1 - 0.00022 20.4 0.1 0.00035 19.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 GAP91563.1 - 0.00025 20.2 0.2 0.00048 19.2 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 GAP91563.1 - 0.0022 16.9 0.1 0.0032 16.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 GAP91563.1 - 0.0022 18.3 0.8 0.012 15.9 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 GAP91563.1 - 0.0082 15.7 0.4 0.021 14.4 0.3 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 GAP91563.1 - 0.009 16.2 0.0 0.021 15.0 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Trp_halogenase PF04820.9 GAP91563.1 - 0.012 14.3 0.5 0.023 13.3 0.4 1.4 1 0 0 1 1 1 0 Tryptophan halogenase DUF743 PF05332.6 GAP91563.1 - 0.055 13.4 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF743) 3HCDH_N PF02737.13 GAP91563.1 - 0.22 11.1 0.5 0.38 10.4 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.11 GAP91564.1 - 1.6e-29 102.7 25.1 1.6e-29 102.7 17.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily NfeD PF01957.13 GAP91564.1 - 0.023 14.8 8.8 0.97 9.5 0.0 3.8 3 1 1 4 4 4 0 NfeD-like C-terminal, partner-binding ELF PF03317.8 GAP91564.1 - 0.26 10.5 2.3 0.43 9.8 1.6 1.3 1 0 0 1 1 1 0 ELF protein HHH PF00633.18 GAP91565.1 - 0.055 13.2 0.3 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF4309 PF14172.1 GAP91565.1 - 0.096 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4309) Pkinase PF00069.20 GAP91566.1 - 3.2e-49 167.4 0.0 3.9e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP91566.1 - 7.7e-23 80.8 0.0 9.5e-23 80.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP91566.1 - 7e-05 21.9 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAP91566.1 - 0.00022 20.3 0.0 0.00054 19.0 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Aldo_ket_red PF00248.16 GAP91566.1 - 0.012 14.4 0.0 0.068 11.9 0.0 1.9 2 0 0 2 2 2 0 Aldo/keto reductase family Pox_ser-thr_kin PF05445.6 GAP91566.1 - 0.17 10.6 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Lipase_GDSL PF00657.17 GAP91567.1 - 2.8e-13 50.2 0.2 3.1e-13 50.0 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 GAP91567.1 - 1.5e-09 38.2 1.9 2.4e-09 37.5 1.3 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family WD40 PF00400.27 GAP91569.1 - 9e-16 57.0 0.8 0.00024 20.8 0.0 5.2 5 1 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 GAP91569.1 - 0.075 11.1 0.8 0.72 7.9 0.2 2.4 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Pkinase PF00069.20 GAP91570.1 - 1.9e-44 151.7 0.0 9.7e-40 136.3 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAP91570.1 - 2.7e-13 49.6 0.0 2e-07 30.3 0.0 3.8 4 0 0 4 4 4 2 Protein tyrosine kinase Kinase-like PF14531.1 GAP91570.1 - 2.2e-06 26.8 0.0 0.022 13.7 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 GAP91570.1 - 3.1e-06 27.0 0.0 0.031 13.9 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 GAP91570.1 - 0.05 12.6 0.0 0.19 10.7 0.0 1.9 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Hid1 PF12722.2 GAP91570.1 - 5.9 4.4 6.9 8.2 3.9 4.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 GAP91570.1 - 7 4.2 8.7 9.7 3.7 6.1 1.1 1 0 0 1 1 1 0 Ycf1 Cnd1_N PF12922.2 GAP91571.1 - 1e-55 188.0 0.1 4.4e-55 185.9 0.0 2.2 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 GAP91571.1 - 1.6e-53 181.1 3.8 8.3e-51 172.3 0.1 3.3 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 GAP91571.1 - 2e-10 40.8 2.0 0.00018 21.7 0.0 5.6 5 1 1 6 6 6 2 HEAT repeats HEAT PF02985.17 GAP91571.1 - 7.7e-07 28.6 9.6 0.039 14.0 0.0 6.5 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.1 GAP91571.1 - 4.3e-06 27.0 1.6 0.56 10.7 0.0 5.9 5 0 0 5 5 5 2 HEAT-like repeat DUF2435 PF10363.4 GAP91571.1 - 0.0012 18.6 0.0 0.34 10.8 0.0 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF2435) MFS_1 PF07690.11 GAP91572.1 - 4.5e-12 45.3 27.1 6.6e-12 44.8 18.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1996 PF09362.5 GAP91574.1 - 8.2e-77 258.0 2.6 1.2e-76 257.5 1.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Alpha_L_fucos PF01120.12 GAP91575.1 - 1.8e-74 250.7 0.2 2.2e-53 181.3 0.7 2.1 1 1 1 2 2 2 2 Alpha-L-fucosidase GHL6 PF14871.1 GAP91575.1 - 0.0013 18.7 0.0 0.0035 17.3 0.0 1.8 2 0 0 2 2 2 1 Hypothetical glycosyl hydrolase 6 DJ-1_PfpI PF01965.19 GAP91577.1 - 9.5e-11 41.3 0.0 4.2e-10 39.2 0.0 2.0 1 1 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 GAP91577.1 - 0.00017 20.8 0.0 0.0004 19.7 0.0 1.6 1 1 0 1 1 1 1 Putative amidotransferase HAD_2 PF13419.1 GAP91578.1 - 3.9e-24 85.8 0.0 6.9e-24 85.0 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAP91578.1 - 9e-05 22.1 0.0 0.00015 21.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 GAP91578.1 - 0.0002 21.8 0.0 0.00042 20.7 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HsbA PF12296.3 GAP91578.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Hydrophobic surface binding protein A DDRGK PF09756.4 GAP91579.1 - 0.091 12.1 0.6 0.14 11.5 0.4 1.2 1 0 0 1 1 1 0 DDRGK domain zf-C2H2 PF00096.21 GAP91580.1 - 0.0006 19.9 2.8 0.00099 19.3 0.1 2.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP91580.1 - 0.031 14.6 0.1 0.031 14.6 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger GrpE PF01025.14 GAP91580.1 - 0.086 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 GrpE DUF3505 PF12013.3 GAP91580.1 - 5.8 7.1 7.7 41 4.4 5.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3505) DUF367 PF04034.8 GAP91582.1 - 5.2e-46 155.3 0.0 7.6e-46 154.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) VHS PF00790.14 GAP91583.1 - 1.9e-34 118.3 0.0 2.4e-32 111.5 0.0 2.6 1 1 0 1 1 1 1 VHS domain GAT PF03127.9 GAP91583.1 - 1.6e-22 79.4 0.0 3.6e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 GAP91583.1 - 1.5e-18 67.1 0.0 2.8e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain Pol_alpha_B_N PF08418.5 GAP91583.1 - 7.7 5.9 6.9 14 5.0 4.8 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal GTP_EFTU PF00009.22 GAP91584.1 - 1.9e-37 128.5 3.1 7.5e-37 126.5 2.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 GAP91584.1 - 1.1e-24 86.3 0.0 2.7e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 GAP91584.1 - 4.8e-10 39.4 0.6 6.5e-07 29.3 0.0 2.7 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAP91584.1 - 6.8e-07 29.2 1.4 8.1e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 GAP91584.1 - 6.8e-06 26.5 0.1 2e-05 25.0 0.1 1.9 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 GAP91584.1 - 1.4e-05 24.6 0.1 2.8e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation IF2_N PF04760.10 GAP91584.1 - 0.00086 18.9 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Arf PF00025.16 GAP91584.1 - 0.0012 18.0 0.0 0.0022 17.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 GAP91584.1 - 0.0044 16.2 0.1 0.011 14.9 0.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 GAP91584.1 - 0.016 14.4 0.1 0.036 13.3 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B TrkH PF02386.11 GAP91585.1 - 7e-92 307.7 1.3 8.2e-85 284.4 0.0 2.1 2 0 0 2 2 2 2 Cation transport protein FKBP_C PF00254.23 GAP91586.1 - 8e-33 112.3 0.0 1.2e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Acetyltransf_7 PF13508.1 GAP91588.1 - 3.7e-14 52.6 0.3 7e-14 51.7 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAP91588.1 - 1.7e-13 50.4 0.2 2.4e-13 49.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 GAP91588.1 - 2.3e-07 30.8 0.0 3.3e-07 30.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAP91588.1 - 5.8e-06 26.4 0.0 9.3e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAP91588.1 - 9.8e-06 25.4 0.0 1.3e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAP91588.1 - 4.8e-05 23.5 0.0 6.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAP91588.1 - 0.0051 16.5 0.0 0.0079 15.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 GAP91588.1 - 0.01 15.7 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain IMS PF00817.15 GAP91589.1 - 1.7e-42 144.7 1.7 2e-42 144.5 0.3 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 GAP91589.1 - 2.8e-16 59.6 0.1 6.7e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 GAP91589.1 - 8.6e-05 22.3 0.0 0.00026 20.8 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif Sgf11 PF08209.6 GAP91589.1 - 0.1 11.9 0.2 0.35 10.2 0.1 1.9 1 1 0 1 1 1 0 Sgf11 (transcriptional regulation protein) VPS28 PF03997.7 GAP91589.1 - 0.15 11.6 1.7 0.17 11.4 0.3 1.6 2 0 0 2 2 2 0 VPS28 protein Alpha-L-AF_C PF06964.7 GAP91590.1 - 1.8e-31 109.2 0.0 2.7e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus CBM_4_9 PF02018.12 GAP91590.1 - 0.0012 18.8 0.1 0.0036 17.2 0.1 1.9 1 0 0 1 1 1 1 Carbohydrate binding domain RPEL PF02755.10 GAP91591.1 - 2.4e-19 68.0 3.2 7.2e-10 37.8 0.3 2.4 2 0 0 2 2 2 2 RPEL repeat MCPVI PF02993.9 GAP91591.1 - 0.46 10.5 2.1 0.6 10.2 1.5 1.1 1 0 0 1 1 1 0 Minor capsid protein VI Ribonuc_L-PSP PF01042.16 GAP91592.1 - 5.8e-39 132.5 0.1 6.4e-39 132.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP MFS_1 PF07690.11 GAP91593.1 - 5.2e-29 101.0 21.9 5.2e-29 101.0 15.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Pec_lyase_C PF00544.14 GAP91594.1 - 3.7e-46 157.1 3.0 6.9e-46 156.2 2.1 1.4 1 0 0 1 1 1 1 Pectate lyase Acetyltransf_1 PF00583.19 GAP91595.1 - 1.1e-09 38.2 0.1 1.7e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 GAP91595.1 - 2.2e-06 27.7 0.0 2.6e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAP91595.1 - 5.2e-06 26.5 0.0 8.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TLD PF07534.11 GAP91596.1 - 2e-25 89.4 0.0 7.2e-25 87.6 0.0 1.9 1 1 0 1 1 1 1 TLD MUG2_C PF08593.5 GAP91596.1 - 1.7e-12 47.3 0.1 5.6e-12 45.7 0.0 2.0 2 0 0 2 2 2 1 Meiotically up-regulated glycoproteins C-terminal HIG_1_N PF04588.8 GAP91597.1 - 4.1e-20 71.2 1.6 6.7e-20 70.5 1.1 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region SpaB_C PF14028.1 GAP91597.1 - 0.1 12.1 8.8 0.12 11.8 6.1 1.2 1 0 0 1 1 1 0 SpaB C-terminal domain Phage_lysis PF03245.8 GAP91597.1 - 0.3 11.0 11.7 0.68 9.9 8.1 1.5 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein DUF1168 PF06658.7 GAP91597.1 - 0.98 8.9 11.9 0.12 11.9 5.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) Abhydrolase_6 PF12697.2 GAP91599.1 - 3.3e-17 63.1 6.8 5e-17 62.5 4.7 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP91599.1 - 1.2e-06 28.3 9.0 2.5e-06 27.3 6.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP91599.1 - 0.027 14.0 0.1 1.1 8.7 0.1 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Thioesterase PF00975.15 GAP91599.1 - 0.57 10.3 2.5 0.48 10.6 0.5 1.7 2 0 0 2 2 2 0 Thioesterase domain zf-RING_2 PF13639.1 GAP91600.1 - 3.5e-12 45.9 4.4 6.1e-12 45.1 3.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAP91600.1 - 2.4e-07 30.6 6.0 4.4e-07 29.8 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAP91600.1 - 3e-06 27.2 1.2 6.7e-06 26.1 0.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 GAP91600.1 - 4.9e-06 26.1 3.6 8.1e-06 25.4 2.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 GAP91600.1 - 1.5e-05 24.5 5.0 2.6e-05 23.7 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAP91600.1 - 0.00016 21.2 2.7 0.0003 20.4 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAP91600.1 - 0.0023 17.7 5.6 0.0045 16.8 3.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.1 GAP91600.1 - 0.0041 16.8 0.1 0.0041 16.8 0.1 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-Apc11 PF12861.2 GAP91600.1 - 0.0064 16.2 1.8 0.014 15.2 1.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 GAP91600.1 - 0.0085 15.7 1.6 0.015 15.0 0.5 1.9 1 1 0 1 1 1 1 RING-type zinc-finger HemY_N PF07219.8 GAP91600.1 - 0.034 13.7 1.1 0.065 12.8 0.8 1.4 1 0 0 1 1 1 0 HemY protein N-terminus Rtf2 PF04641.7 GAP91600.1 - 0.045 12.9 0.2 0.067 12.3 0.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger FANCL_C PF11793.3 GAP91600.1 - 0.059 13.3 2.5 0.13 12.2 1.8 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain YdjO PF14169.1 GAP91600.1 - 0.074 12.5 1.8 0.79 9.2 0.4 2.4 2 0 0 2 2 2 0 Cold-inducible protein YdjO RINGv PF12906.2 GAP91600.1 - 0.097 12.7 3.8 0.17 11.9 2.6 1.4 1 0 0 1 1 1 0 RING-variant domain Epiglycanin_C PF14654.1 GAP91600.1 - 0.13 12.2 0.3 0.29 11.1 0.2 1.5 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region zf-RING_4 PF14570.1 GAP91600.1 - 0.14 11.7 1.6 0.31 10.6 1.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 GAP91600.1 - 0.23 11.0 3.3 0.51 9.8 2.3 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.1 GAP91600.1 - 0.24 10.9 2.1 1.1 8.8 1.5 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Utp11 PF03998.8 GAP91603.1 - 1.4e-48 165.8 20.4 1.6e-48 165.6 14.1 1.1 1 0 0 1 1 1 1 Utp11 protein Dscam_C PF12355.3 GAP91604.1 - 0.13 12.4 1.3 0.26 11.5 0.9 1.4 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal GST_N_3 PF13417.1 GAP91605.1 - 2.5e-29 101.2 0.1 4.7e-29 100.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAP91605.1 - 2.8e-20 72.0 1.0 6.2e-20 70.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAP91605.1 - 1.5e-11 44.2 0.1 2.6e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAP91605.1 - 0.0002 21.2 0.0 0.00036 20.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAP91605.1 - 0.00065 19.5 1.3 0.0015 18.3 0.9 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 GAP91605.1 - 0.0049 16.8 0.0 0.019 14.9 0.0 2.0 1 1 1 2 2 2 1 Glutaredoxin Cytochrom_C_asm PF01578.15 GAP91606.1 - 0.16 11.4 0.4 0.55 9.7 0.1 2.0 2 1 0 2 2 2 0 Cytochrome C assembly protein DNase_NucA_NucB PF14040.1 GAP91607.1 - 1.5e-08 34.7 0.0 2.5e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB DUF676 PF05057.9 GAP91608.1 - 0.027 13.7 0.0 0.1 11.8 0.0 1.9 2 0 0 2 2 2 0 Putative serine esterase (DUF676) PGAP1 PF07819.8 GAP91608.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.5 1 1 0 1 1 1 0 PGAP1-like protein WD40 PF00400.27 GAP91609.1 - 5.1e-14 51.5 1.2 1.6e-12 46.7 0.0 3.3 4 0 0 4 4 4 1 WD domain, G-beta repeat Inh PF02974.9 GAP91609.1 - 0.028 14.0 0.1 0.056 13.0 0.1 1.5 1 0 0 1 1 1 0 Protease inhibitor Inh MARVEL PF01284.18 GAP91610.1 - 1e-20 74.0 21.5 1.2e-20 73.8 14.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain ketoacyl-synt PF00109.21 GAP91610.1 - 0.019 14.4 0.3 0.029 13.8 0.2 1.2 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Ndc1_Nup PF09531.5 GAP91610.1 - 0.78 8.0 7.2 0.82 8.0 5.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Oxidored_molyb PF00174.14 GAP91611.1 - 4.2e-52 175.9 0.0 6.5e-52 175.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 GAP91611.1 - 3.9e-29 100.9 0.8 9.1e-29 99.7 0.2 1.8 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.23 GAP91611.1 - 5.6e-13 48.4 0.0 1e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PLRV_ORF5 PF01690.12 GAP91611.1 - 0.0091 15.1 6.6 0.02 14.0 4.6 1.5 1 0 0 1 1 1 1 Potato leaf roll virus readthrough protein Trypan_PARP PF05887.6 GAP91611.1 - 7.9 6.2 11.0 0.4 10.4 3.6 1.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Catalase PF00199.14 GAP91612.1 - 2.2e-169 563.1 0.5 3e-169 562.7 0.3 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 GAP91612.1 - 8.4e-14 51.1 0.0 3.6e-13 49.1 0.0 2.1 2 0 0 2 2 2 1 Catalase-related immune-responsive MFS_1 PF07690.11 GAP91613.1 - 1.1e-28 100.0 26.1 1.1e-28 100.0 18.1 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP91613.1 - 3.2e-28 98.5 22.9 1.7e-27 96.1 15.9 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter PIRT PF15099.1 GAP91613.1 - 0.8 8.9 5.2 0.29 10.3 0.4 2.5 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family Acetyltransf_7 PF13508.1 GAP91614.1 - 3.3e-09 36.7 0.0 5.1e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAP91614.1 - 9.7e-09 35.1 0.1 1.4e-08 34.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAP91614.1 - 2e-05 24.2 0.0 3.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 GAP91614.1 - 0.00014 21.9 0.1 0.00044 20.3 0.1 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAP91614.1 - 0.0037 17.1 0.0 0.0059 16.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CBM_1 PF00734.13 GAP91615.1 - 1.6e-10 40.4 5.0 1.6e-10 40.4 3.4 2.5 3 0 0 3 3 3 1 Fungal cellulose binding domain Toxin_7 PF05980.7 GAP91615.1 - 0.0055 16.7 0.5 0.0098 15.9 0.3 1.4 1 0 0 1 1 1 1 Toxin 7 Mucin PF01456.12 GAP91615.1 - 0.81 9.4 29.7 1.4 8.7 20.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Methyltransf_23 PF13489.1 GAP91616.1 - 4e-18 65.6 0.0 6.1e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP91616.1 - 7.7e-13 48.7 0.0 2e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP91616.1 - 7.2e-10 38.6 0.0 3.7e-09 36.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP91616.1 - 1.9e-09 37.8 0.0 6e-09 36.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP91616.1 - 1.1e-08 35.6 0.0 5.7e-08 33.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP91616.1 - 4.7e-07 29.1 0.0 5.6e-06 25.6 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 GAP91616.1 - 2.3e-05 24.6 0.0 6e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAP91616.1 - 0.00012 21.1 0.0 0.00023 20.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 GAP91616.1 - 0.00036 19.9 0.0 0.00076 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 GAP91616.1 - 0.0013 18.7 0.2 0.007 16.3 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 GAP91616.1 - 0.0014 17.8 0.0 0.0024 17.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase FtsJ PF01728.14 GAP91616.1 - 0.0031 17.5 0.0 0.007 16.3 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 GAP91616.1 - 0.0032 16.6 0.1 0.0088 15.1 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 GAP91616.1 - 0.0089 15.1 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DUF938 PF06080.7 GAP91616.1 - 0.04 13.4 0.2 0.086 12.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Methyltransf_16 PF10294.4 GAP91616.1 - 0.078 12.4 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_29 PF03141.11 GAP91616.1 - 0.1 10.8 0.1 0.39 9.0 0.0 1.9 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.14 GAP91616.1 - 0.13 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.6 GAP91616.1 - 0.14 10.8 0.0 0.66 8.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) HET PF06985.6 GAP91617.1 - 4.2e-20 72.3 2.6 4e-18 65.9 1.8 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PIG-S PF10510.4 GAP91619.1 - 1.6e-139 465.8 0.0 2e-139 465.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein DUF3439 PF11921.3 GAP91619.1 - 0.11 12.2 5.8 0.25 11.1 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 GAP91619.1 - 0.93 7.3 11.9 1.6 6.6 8.2 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 AMP-binding PF00501.23 GAP91620.1 - 4.9e-69 232.7 0.0 6.5e-69 232.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAP91620.1 - 1.4e-09 38.7 0.0 3.3e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Diphthamide_syn PF01866.12 GAP91621.1 - 6.4e-48 163.5 0.0 9.4e-47 159.7 0.0 2.1 1 1 0 1 1 1 1 Putative diphthamide synthesis protein MARVEL PF01284.18 GAP91622.1 - 0.00049 19.9 18.5 0.00066 19.5 12.8 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF4293 PF14126.1 GAP91622.1 - 0.12 12.3 3.4 0.2 11.5 2.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) DUF3366 PF11846.3 GAP91622.1 - 0.19 11.5 1.4 0.34 10.7 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) zf-DHHC PF01529.15 GAP91622.1 - 1.3 8.4 4.9 6.6 6.0 3.4 2.1 1 1 0 1 1 1 0 DHHC palmitoyltransferase zf-MYND PF01753.13 GAP91623.1 - 2.7e-05 23.9 9.9 5.6e-05 22.9 6.9 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 GAP91623.1 - 0.43 10.4 8.2 0.92 9.4 5.7 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.11 GAP91623.1 - 0.86 9.3 14.2 0.26 10.9 7.6 1.9 2 0 0 2 2 2 0 HIT zinc finger Neur_chan_memb PF02932.11 GAP91625.1 - 0.22 11.3 8.1 0.85 9.4 2.7 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4448 PF14610.1 GAP91626.1 - 1.5e-27 96.3 0.0 2.5e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Pyr_redox PF00070.22 GAP91628.1 - 3.8e-17 62.4 1.0 3.8e-15 56.0 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAP91628.1 - 7.4e-15 55.3 5.5 1e-06 28.8 0.1 3.9 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP91628.1 - 2.2e-08 34.4 0.2 0.039 14.0 0.0 3.1 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 GAP91628.1 - 1.2e-05 25.5 0.3 0.0013 19.0 0.0 2.4 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 GAP91628.1 - 1.8e-05 24.6 0.1 0.018 15.0 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 GAP91628.1 - 5.5e-05 22.3 1.4 0.58 9.1 0.0 3.0 2 1 1 3 3 3 3 FAD binding domain Thi4 PF01946.12 GAP91628.1 - 9.3e-05 21.6 1.1 0.00064 18.8 0.1 2.5 2 1 0 3 3 3 1 Thi4 family Shikimate_DH PF01488.15 GAP91628.1 - 0.00014 21.9 0.3 0.11 12.5 0.0 2.2 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 GAP91628.1 - 0.00077 18.4 2.7 0.21 10.4 0.0 2.8 2 1 1 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 GAP91628.1 - 0.00097 18.1 0.2 0.32 9.8 0.0 2.8 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 GAP91628.1 - 0.0015 17.4 6.8 0.079 11.7 0.3 2.9 2 1 0 3 3 3 2 FAD binding domain FAD_oxidored PF12831.2 GAP91628.1 - 0.0028 16.7 3.3 0.003 16.6 1.5 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 GAP91628.1 - 0.0063 15.4 4.4 0.41 9.4 0.1 3.5 3 1 1 4 4 4 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 GAP91628.1 - 0.032 12.8 0.1 0.29 9.7 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Helicase_IV_N PF12462.3 GAP91628.1 - 0.16 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal PQ-loop PF04193.9 GAP91629.1 - 1.2e-22 79.2 11.0 8e-20 70.1 1.7 3.1 2 1 1 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 GAP91629.1 - 0.028 14.2 0.6 0.13 12.1 0.4 2.2 1 1 0 1 1 1 0 Sugar efflux transporter for intercellular exchange Wzz PF02706.10 GAP91629.1 - 0.051 13.3 2.0 0.23 11.2 0.5 2.2 2 0 0 2 2 2 0 Chain length determinant protein CRAL_TRIO PF00650.15 GAP91630.1 - 9.5e-13 47.9 0.0 1.4e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAP91630.1 - 0.0087 16.1 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Defensin_propep PF00879.13 GAP91630.1 - 0.4 10.6 6.2 0.98 9.4 4.3 1.7 1 0 0 1 1 1 0 Defensin propeptide Pex14_N PF04695.8 GAP91630.1 - 2 8.4 6.8 15 5.5 2.8 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NPR2 PF06218.6 GAP91631.1 - 2.7e-116 388.7 0.0 3.6e-116 388.3 0.0 1.1 1 0 0 1 1 1 1 Nitrogen permease regulator 2 API5 PF05918.6 GAP91631.1 - 7.3 4.9 7.2 12 4.2 5.0 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) tRNA-synt_1b PF00579.20 GAP91632.1 - 1.1e-70 238.0 0.0 1.4e-70 237.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Glyco_hydro_18 PF00704.23 GAP91633.1 - 8.6e-76 255.5 3.3 1.4e-75 254.9 2.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 GAP91633.1 - 1.5e-05 24.8 10.0 1.5e-05 24.8 6.9 4.8 5 0 0 5 5 5 1 Chitin recognition protein CoaE PF01121.15 GAP91633.1 - 0.037 13.4 0.1 0.21 10.9 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase LysM PF01476.15 GAP91634.1 - 8.5e-23 79.9 2.3 4e-05 23.4 0.0 5.3 5 0 0 5 5 5 4 LysM domain UPF0203 PF05254.7 GAP91634.1 - 0.36 10.7 0.0 0.36 10.7 0.0 3.4 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0203) F-box-like PF12937.2 GAP91635.1 - 0.05 13.3 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 F-box-like CybS PF05328.7 GAP91636.1 - 1.6e-54 183.1 0.0 2.1e-54 182.7 0.0 1.1 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 GAP91636.1 - 0.029 14.1 2.3 0.72 9.7 1.6 2.2 1 1 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Vps53_N PF04100.7 GAP91637.1 - 1.7e-101 339.8 0.0 2.8e-101 339.0 0.0 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 GAP91637.1 - 4.4e-08 32.3 1.5 7.7e-08 31.5 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Sec15 PF04091.7 GAP91637.1 - 9.8e-05 21.8 1.1 9.8e-05 21.8 0.7 1.7 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like DUF2451 PF10474.4 GAP91637.1 - 0.023 14.4 0.1 0.056 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) Seryl_tRNA_N PF02403.17 GAP91637.1 - 0.2 11.7 1.5 1.3 9.0 0.2 2.8 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ubiquitin PF00240.18 GAP91638.1 - 5e-18 64.2 0.0 8.5e-18 63.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 GAP91638.1 - 1e-08 34.7 1.3 7.8e-08 31.9 0.0 2.8 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.3 GAP91638.1 - 0.00034 20.2 0.0 0.00066 19.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 GAP91638.1 - 0.00077 19.3 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 GAP91638.1 - 0.017 15.3 0.0 0.039 14.1 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain ADH_zinc_N PF00107.21 GAP91639.1 - 3.3e-34 117.2 1.9 5.5e-34 116.5 1.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAP91639.1 - 1.2e-10 42.3 0.0 2.9e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP91639.1 - 3e-06 26.9 0.0 9.2e-06 25.3 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 GAP91639.1 - 0.067 12.7 3.2 0.12 11.9 1.8 1.7 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1254 PF06863.7 GAP91639.1 - 0.12 12.2 0.2 0.42 10.4 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1254) Lactamase_B PF00753.22 GAP91640.1 - 5e-07 29.5 0.0 7.2e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAP91640.1 - 0.014 14.9 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain HypA PF01155.14 GAP91640.1 - 0.044 13.4 0.2 0.087 12.5 0.1 1.4 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 GAP91640.1 - 0.13 12.0 0.5 0.23 11.3 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-C3HC4_3 PF13920.1 GAP91640.1 - 0.13 11.9 0.5 0.22 11.2 0.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Amidase PF01425.16 GAP91641.1 - 8.9e-90 301.6 0.0 1e-89 301.4 0.0 1.0 1 0 0 1 1 1 1 Amidase Alpha_kinase PF02816.13 GAP91642.1 - 6.2e-38 130.3 0.0 7.1e-38 130.1 0.0 1.0 1 0 0 1 1 1 1 Alpha-kinase family Peptidase_S9 PF00326.16 GAP91643.1 - 5.8e-37 126.9 0.1 8.6e-37 126.4 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.7 GAP91643.1 - 9.5e-13 47.5 0.8 5.2e-07 29.1 0.2 3.6 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Abhydrolase_5 PF12695.2 GAP91643.1 - 2.4e-11 43.5 0.4 4.3e-11 42.7 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP91643.1 - 9.7e-10 38.7 4.4 3.7e-09 36.8 3.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 GAP91643.1 - 1.7e-05 24.2 0.1 0.013 14.8 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 GAP91643.1 - 7.1e-05 22.3 0.0 0.37 10.1 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 GAP91643.1 - 8.3e-05 22.2 0.0 0.00018 21.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold LIP PF03583.9 GAP91643.1 - 0.00024 20.4 0.6 0.0014 17.9 0.6 1.8 2 0 0 2 2 2 1 Secretory lipase DPPIV_N PF00930.16 GAP91643.1 - 0.00089 17.9 0.0 0.0087 14.6 0.0 2.4 2 1 1 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_4 PF08386.5 GAP91643.1 - 0.015 15.2 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Esterase_phd PF10503.4 GAP91643.1 - 0.026 13.7 0.1 0.2 10.8 0.0 2.0 2 0 0 2 2 2 0 Esterase PHB depolymerase AXE1 PF05448.7 GAP91643.1 - 0.14 10.6 0.1 0.28 9.6 0.1 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Acetyltransf_1 PF00583.19 GAP91645.1 - 2.8e-18 65.7 0.1 5.1e-18 64.8 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAP91645.1 - 6.8e-11 42.3 0.1 1.1e-10 41.6 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAP91645.1 - 4.5e-09 36.3 0.0 6.8e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAP91645.1 - 4.6e-09 35.9 0.1 1.1e-08 34.7 0.1 1.7 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 GAP91645.1 - 9e-09 35.3 0.0 4.2e-07 29.9 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAP91645.1 - 5.7e-07 29.6 0.0 8.7e-07 29.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAP91645.1 - 8.2e-06 26.0 0.0 1.1e-05 25.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAP91645.1 - 0.00032 20.5 0.0 0.00064 19.5 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 GAP91645.1 - 0.00057 19.7 0.0 0.00084 19.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 GAP91645.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-CCCH PF00642.19 GAP91646.1 - 1.8e-08 33.8 17.8 3.2e-07 29.8 1.5 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 GAP91646.1 - 5.1e-05 23.0 0.0 8.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAP91646.1 - 0.0095 15.5 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP91646.1 - 0.039 13.9 0.0 0.087 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Oxysterol_BP PF01237.13 GAP91647.1 - 6.3e-89 297.9 0.0 8.4e-89 297.5 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein AIG2 PF06094.7 GAP91648.1 - 0.07 13.6 0.0 0.21 12.0 0.0 1.8 1 0 0 1 1 1 0 AIG2-like family Poly_export PF02563.11 GAP91648.1 - 0.11 12.2 0.0 0.72 9.6 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis/export protein Glyco_transf_22 PF03901.12 GAP91649.1 - 3.7e-37 128.3 13.9 5.2e-37 127.8 9.6 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Yos1 PF08571.5 GAP91650.1 - 6.9e-28 96.5 1.0 7.8e-28 96.3 0.7 1.0 1 0 0 1 1 1 1 Yos1-like PsbT PF01405.12 GAP91650.1 - 0.44 10.1 3.4 4.5 6.9 0.9 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre T protein UCH PF00443.24 GAP91651.1 - 9.5e-62 208.5 0.0 9.5e-62 208.5 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAP91651.1 - 2.1e-28 99.6 7.6 5.9e-24 85.0 0.0 2.6 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUF3292 PF11696.3 GAP91651.1 - 6 4.5 8.0 11 3.7 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Mito_carr PF00153.22 GAP91652.1 - 1.6e-52 175.1 6.0 9.2e-20 70.1 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein CBS PF00571.23 GAP91653.1 - 4.8e-05 23.0 0.0 0.33 10.7 0.0 3.2 3 0 0 3 3 3 3 CBS domain Tricorn_C1 PF14684.1 GAP91653.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Tricorn protease C1 domain Epimerase PF01370.16 GAP91655.1 - 7.3e-20 71.4 0.0 1e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 GAP91655.1 - 2.1e-08 33.4 0.0 3.1e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 GAP91655.1 - 1.6e-07 31.3 0.0 6.9e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 GAP91655.1 - 5.2e-05 22.0 0.0 8.1e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 GAP91655.1 - 0.0003 20.5 0.0 0.00056 19.6 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAP91655.1 - 0.0019 18.2 0.1 0.017 15.1 0.1 2.3 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAP91655.1 - 0.0057 15.6 0.0 0.0088 15.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Saccharop_dh PF03435.13 GAP91655.1 - 0.0085 15.1 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase F_actin_cap_B PF01115.12 GAP91656.1 - 9.4e-104 345.8 0.0 1.1e-103 345.6 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit BAH PF01426.13 GAP91657.1 - 6.6e-06 25.8 0.1 1.3e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 GAP91657.1 - 0.0021 17.7 2.2 0.0021 17.7 1.5 2.2 2 0 0 2 2 2 1 PHD-finger ATG22 PF11700.3 GAP91658.1 - 6.5e-173 575.5 19.7 7.7e-173 575.3 13.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 GAP91658.1 - 0.00032 19.5 7.7 0.00032 19.5 5.4 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily Glyco_hydro_10 PF00331.15 GAP91659.1 - 5.9e-33 114.2 0.2 6.7e-33 114.0 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF4339 PF14237.1 GAP91659.1 - 0.02 14.4 0.1 0.054 13.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4339) Ribosomal_S21e PF01249.13 GAP91659.1 - 0.12 12.3 0.0 0.34 10.8 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein S21e DUF1680 PF07944.7 GAP91660.1 - 6.6e-21 74.1 0.1 7.3e-20 70.7 0.0 2.0 1 1 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) CDC45 PF02724.9 GAP91661.1 - 0.46 8.4 9.5 0.6 8.0 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.7 GAP91661.1 - 0.72 9.5 10.7 0.98 9.0 7.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3295 PF11702.3 GAP91661.1 - 1.8 7.4 8.1 2.2 7.1 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Rhamno_transf PF11316.3 GAP91661.1 - 2.6 7.1 5.7 4.4 6.4 3.9 1.3 1 0 0 1 1 1 0 Putative rhamnosyl transferase Nop14 PF04147.7 GAP91661.1 - 3.7 5.3 16.5 4.7 4.9 11.4 1.0 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.6 GAP91661.1 - 9.1 3.9 6.0 13 3.4 4.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRN3 PF05327.6 GAP91661.1 - 9.6 4.1 9.3 13 3.7 6.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Asp_protease_2 PF13650.1 GAP91662.1 - 1.6e-22 79.8 0.0 2.7e-10 40.5 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.1 GAP91662.1 - 2.9e-13 49.4 0.0 2.1e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP PF00077.15 GAP91662.1 - 5.5e-08 32.6 0.0 0.005 16.7 0.0 2.5 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease PF09668.5 GAP91662.1 - 3.4e-06 26.6 0.0 0.00052 19.5 0.0 2.3 2 0 0 2 2 2 2 Aspartyl protease RVP_2 PF08284.6 GAP91662.1 - 0.0041 17.0 0.0 0.17 11.7 0.0 2.4 2 1 0 2 2 2 1 Retroviral aspartyl protease DUF2384 PF09722.5 GAP91663.1 - 0.023 14.5 0.0 0.07 13.0 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2384) C2 PF00168.25 GAP91664.1 - 3.8e-70 231.7 0.2 5.7e-20 70.9 0.0 5.4 5 0 0 5 5 5 5 C2 domain DUF2404 PF10296.4 GAP91664.1 - 0.059 13.5 0.0 0.28 11.3 0.0 2.2 2 0 0 2 2 2 0 Putative integral membrane protein conserved region (DUF2404) FKBP_C PF00254.23 GAP91664.1 - 0.096 12.7 0.0 1.2 9.1 0.0 2.6 2 0 0 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase ThiS PF02597.15 GAP91665.1 - 2.8e-08 34.0 0.0 8.4e-08 32.5 0.0 1.7 1 1 0 1 1 1 1 ThiS family Mob1_phocein PF03637.12 GAP91666.1 - 4.1e-39 134.0 1.6 5.5e-21 74.9 0.0 2.1 2 0 0 2 2 2 2 Mob1/phocein family Leo1 PF04004.8 GAP91667.1 - 4.9e-25 88.1 0.1 4.9e-25 88.1 0.1 2.3 2 0 0 2 2 2 1 Leo1-like protein DUF3336 PF11815.3 GAP91668.1 - 4.8e-34 116.9 0.7 2.8e-33 114.4 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 GAP91668.1 - 2.6e-14 53.6 0.0 6.4e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase BOP1NT PF08145.7 GAP91671.1 - 3.5e-104 348.1 7.4 1e-103 346.6 5.6 1.4 2 0 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.27 GAP91671.1 - 7e-32 108.1 11.5 1.7e-10 40.3 0.4 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 GAP91671.1 - 0.16 10.6 0.0 1.5 7.4 0.0 2.1 2 0 0 2 2 2 0 Nup133 N terminal like FAA_hydrolase PF01557.13 GAP91672.1 - 6.3e-62 208.8 0.0 8.4e-62 208.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family PAS_5 PF07310.8 GAP91672.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 PAS domain SDA1 PF05285.7 GAP91673.1 - 0.16 11.2 8.8 0.22 10.7 6.1 1.2 1 0 0 1 1 1 0 SDA1 DUF2052 PF09747.4 GAP91673.1 - 2.3 8.1 12.2 3.4 7.5 4.5 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) BRO1 PF03097.13 GAP91674.1 - 0.00027 19.8 0.6 0.0008 18.2 0.4 1.7 1 1 0 1 1 1 1 BRO1-like domain Alg6_Alg8 PF03155.10 GAP91675.1 - 4.3e-130 434.6 23.4 2.4e-82 277.2 6.0 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family NPP1 PF05630.6 GAP91676.1 - 1e-73 247.5 1.3 1.2e-73 247.2 0.9 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) C2 PF00168.25 GAP91677.1 - 1.6e-10 40.6 0.0 2.9e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain S-methyl_trans PF02574.11 GAP91678.1 - 4.4e-21 75.4 0.0 4.1e-20 72.2 0.0 2.0 1 1 0 1 1 1 1 Homocysteine S-methyltransferase Methyltransf_11 PF08241.7 GAP91680.1 - 1.9e-21 76.3 0.0 3.9e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP91680.1 - 2.6e-16 59.5 0.0 4e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP91680.1 - 1.4e-14 54.1 0.0 2.4e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP91680.1 - 9.1e-13 48.4 0.0 1.9e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP91680.1 - 8.2e-11 42.4 0.0 1.7e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP91680.1 - 1.7e-10 41.2 0.0 3.7e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP91680.1 - 1.9e-10 40.2 0.0 3.4e-10 39.4 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 GAP91680.1 - 7.3e-09 35.0 0.0 1.1e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 GAP91680.1 - 4.4e-08 33.1 1.0 4.3e-07 29.9 0.2 2.6 2 1 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 GAP91680.1 - 5.8e-06 25.8 0.0 1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 GAP91680.1 - 7e-05 22.2 0.0 0.00011 21.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain FmrO PF07091.6 GAP91680.1 - 0.0016 17.5 0.0 0.009 15.0 0.0 1.9 1 1 1 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_32 PF13679.1 GAP91680.1 - 0.003 17.2 0.0 0.0051 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 GAP91680.1 - 0.0045 16.5 0.0 0.0067 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.13 GAP91680.1 - 0.035 13.2 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase TehB PF03848.9 GAP91680.1 - 0.038 13.1 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_8 PF05148.10 GAP91680.1 - 0.042 13.4 0.0 0.86 9.1 0.0 2.4 1 1 0 1 1 1 0 Hypothetical methyltransferase PrmA PF06325.8 GAP91680.1 - 0.063 12.3 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.15 GAP91680.1 - 0.067 12.2 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DREV PF05219.7 GAP91680.1 - 0.08 11.8 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase PAT1 PF09770.4 GAP91681.1 - 1.5 6.9 7.1 2.1 6.4 4.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MFS_1 PF07690.11 GAP91683.1 - 6.6e-25 87.5 36.5 6.6e-25 87.5 25.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Tannase PF07519.6 GAP91684.1 - 2.4e-56 191.3 9.5 2.3e-54 184.9 0.9 3.0 2 1 0 2 2 2 2 Tannase and feruloyl esterase Methyltransf_2 PF00891.13 GAP91685.1 - 4.9e-32 111.0 0.0 1.4e-31 109.5 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase DUF3112 PF11309.3 GAP91686.1 - 0.069 12.9 6.2 0.36 10.6 1.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3112) UbiA PF01040.13 GAP91687.1 - 6e-29 101.0 16.3 8.2e-29 100.5 11.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family HET PF06985.6 GAP91688.1 - 8e-18 64.9 0.0 1.3e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_6 PF12697.2 GAP91689.1 - 1.1e-22 81.0 0.6 1.7e-22 80.4 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP91689.1 - 5.2e-11 42.5 0.0 2.1e-10 40.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP91689.1 - 1.4e-10 41.0 0.0 2.7e-10 40.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 GAP91689.1 - 1.9e-05 24.2 0.0 2.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.3 GAP91689.1 - 2.6e-05 23.9 0.0 5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 GAP91689.1 - 0.0015 17.8 0.0 0.0086 15.3 0.0 2.1 2 1 0 2 2 2 1 Dienelactone hydrolase family Lipase_3 PF01764.20 GAP91689.1 - 0.043 13.4 0.0 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 3) dCMP_cyt_deam_1 PF00383.17 GAP91691.1 - 4.9e-16 58.2 0.6 7.1e-16 57.7 0.4 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 GAP91691.1 - 3.6e-09 36.6 1.8 1.9e-08 34.3 0.1 2.0 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 GAP91691.1 - 0.0058 16.0 1.4 0.6 9.4 0.0 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Sugar_tr PF00083.19 GAP91692.1 - 2e-98 329.9 33.5 2.4e-98 329.6 23.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP91692.1 - 3.3e-22 78.6 26.8 3.3e-22 78.6 18.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sirohm_synth_M PF14824.1 GAP91695.1 - 0.045 12.7 0.1 0.083 11.8 0.0 1.4 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central p450 PF00067.17 GAP91697.1 - 9.2e-72 242.0 0.0 1.1e-71 241.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Choline_kinase PF01633.15 GAP91698.1 - 0.00026 20.6 0.0 0.00041 19.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 GAP91698.1 - 0.0015 17.7 0.1 0.0028 16.8 0.0 1.4 2 0 0 2 2 2 1 Ecdysteroid kinase APH PF01636.18 GAP91698.1 - 0.006 16.3 0.0 0.009 15.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family AAA_17 PF13207.1 GAP91699.1 - 2.8e-05 24.9 0.2 0.0012 19.6 0.0 3.1 2 2 0 3 3 3 1 AAA domain AAA_18 PF13238.1 GAP91699.1 - 0.00087 19.5 0.1 0.67 10.2 0.0 3.4 3 1 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 GAP91699.1 - 0.0093 16.1 0.0 0.48 10.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_29 PF13555.1 GAP91699.1 - 0.026 14.0 0.2 0.12 11.9 0.0 2.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA PF00004.24 GAP91699.1 - 0.027 14.6 0.0 0.59 10.3 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.5 GAP91699.1 - 0.031 13.5 0.0 0.3 10.2 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 MMR_HSR1 PF01926.18 GAP91699.1 - 0.032 14.1 0.1 3.4 7.6 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.1 GAP91699.1 - 0.043 13.7 0.1 0.29 11.0 0.1 2.4 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.15 GAP91699.1 - 0.057 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase CPT PF07931.7 GAP91699.1 - 0.075 12.6 0.2 3.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.1 GAP91699.1 - 0.075 12.9 0.0 0.59 10.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 GAP91699.1 - 0.16 12.2 1.2 0.62 10.3 0.0 2.1 1 1 1 2 2 2 0 AAA domain NUDIX PF00293.23 GAP91700.1 - 5.9e-10 38.9 0.8 1.1e-09 37.9 0.6 1.5 1 1 0 1 1 1 1 NUDIX domain Amidase PF01425.16 GAP91701.1 - 4.9e-74 249.7 0.5 1.3e-73 248.3 0.3 1.6 1 1 0 1 1 1 1 Amidase NmrA PF05368.8 GAP91702.1 - 1.4e-08 34.3 0.0 1.5e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Zn_clus PF00172.13 GAP91704.1 - 1.1e-05 25.2 11.6 1.1e-05 25.2 8.0 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1908 PF08926.6 GAP91704.1 - 0.13 10.9 0.6 0.23 10.1 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) DPBB_1 PF03330.13 GAP91706.1 - 9.3e-07 28.7 0.1 1.8e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Abhydrolase_2 PF02230.11 GAP91707.1 - 4.1e-30 104.8 0.0 2e-22 79.7 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 GAP91707.1 - 5e-06 26.5 1.0 1.3e-05 25.1 0.7 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP91707.1 - 0.00017 21.3 0.0 0.00033 20.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAP91707.1 - 0.001 18.3 0.0 0.013 14.6 0.0 2.3 3 0 0 3 3 3 1 Prolyl oligopeptidase family Cutinase PF01083.17 GAP91707.1 - 0.027 14.2 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 Cutinase FSH1 PF03959.8 GAP91707.1 - 0.032 13.6 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) APH PF01636.18 GAP91708.1 - 2.6e-14 53.5 0.0 3.6e-14 53.0 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAP91708.1 - 5.4e-07 29.3 0.2 1e-06 28.4 0.0 1.4 2 0 0 2 2 2 1 Choline/ethanolamine kinase DUF1679 PF07914.6 GAP91708.1 - 0.00045 18.9 0.3 0.21 10.1 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Pkinase_Tyr PF07714.12 GAP91708.1 - 0.012 14.7 0.0 0.023 13.7 0.0 1.7 1 1 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 GAP91708.1 - 0.018 14.2 0.0 0.1 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain RIO1 PF01163.17 GAP91708.1 - 0.067 12.5 0.5 6.9 5.9 0.0 2.2 2 0 0 2 2 2 0 RIO1 family DUF1593 PF07632.6 GAP91710.1 - 8.8e-93 310.3 0.0 1.1e-92 310.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.10 GAP91710.1 - 0.00057 18.3 0.2 0.00084 17.7 0.1 1.2 1 0 0 1 1 1 1 REJ domain DUF4609 PF15382.1 GAP91710.1 - 0.028 14.1 0.1 2.7 7.7 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4609) Cupin_2 PF07883.6 GAP91711.1 - 1.4e-08 34.0 0.0 2.2e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 GAP91711.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Auxin_BP PF02041.11 GAP91711.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Auxin binding protein Alpha-amylase PF00128.19 GAP91712.1 - 1.1e-61 208.9 2.0 3.7e-61 207.2 1.4 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 GAP91712.1 - 0.0022 18.0 0.0 0.026 14.5 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Glyco_hydro_70 PF02324.11 GAP91712.1 - 0.003 15.4 0.3 0.14 9.9 0.1 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 70 hDGE_amylase PF14701.1 GAP91712.1 - 0.0052 15.7 0.0 0.0074 15.2 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Cellulase PF00150.13 GAP91712.1 - 0.021 14.0 0.1 0.076 12.2 0.0 1.9 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) NSP10 PF09401.5 GAP91712.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA synthesis protein NSP10 Zn_clus PF00172.13 GAP91713.1 - 2.2e-08 33.8 12.1 3.6e-08 33.1 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAP91713.1 - 1.6e-05 23.7 0.1 2.9e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CLPTM1 PF05602.7 GAP91715.1 - 1.6e-156 521.4 0.0 1.9e-156 521.2 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Lysine_decarbox PF03641.9 GAP91716.1 - 8.2e-30 103.3 0.0 1.1e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase Chorismate_bind PF00425.13 GAP91717.1 - 1.9e-58 197.8 0.0 4.2e-53 180.3 0.0 3.3 2 1 0 2 2 2 2 chorismate binding enzyme GATase PF00117.23 GAP91717.1 - 2.9e-23 82.3 0.0 1e-22 80.5 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 GAP91717.1 - 1e-14 54.7 0.0 2e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 GAP91717.1 - 5.9e-05 22.6 0.0 0.0001 21.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 CheC PF04509.7 GAP91717.1 - 0.13 12.0 0.1 15 5.4 0.0 2.8 2 0 0 2 2 2 0 CheC-like family DUF4315 PF14193.1 GAP91717.1 - 0.93 9.4 1.6 1.4 8.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) Glyco_hydro_63 PF03200.11 GAP91718.1 - 2.2e-234 779.9 0.0 2.2e-233 776.6 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 GAP91718.1 - 3.5e-05 22.6 0.0 5.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Trehalase DUF3433 PF11915.3 GAP91719.1 - 1.5e-27 95.5 24.1 2.9e-22 78.6 2.9 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) DUF1777 PF08648.7 GAP91719.1 - 8.8e-26 90.7 37.0 8.8e-26 90.7 25.7 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) HET PF06985.6 GAP91721.1 - 6.9e-09 35.9 0.4 1.9e-05 24.8 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Asp PF00026.18 GAP91722.1 - 9.3e-36 123.6 0.0 1.5e-34 119.7 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 GAP91722.1 - 0.00043 20.7 0.1 12 6.4 0.1 3.4 3 0 0 3 3 3 3 Aspartyl protease gag-asp_proteas PF13975.1 GAP91722.1 - 0.082 12.7 0.0 2.2 8.1 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Elong_Iki1 PF10483.4 GAP91723.1 - 1.3e-20 73.9 0.0 4.4e-20 72.1 0.0 1.7 1 1 0 1 1 1 1 Elongator subunit Iki1 Mucin PF01456.12 GAP91723.1 - 0.012 15.3 9.4 0.015 15.0 6.5 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF1180 PF06679.7 GAP91723.1 - 0.4 10.5 3.5 0.76 9.6 2.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Dicty_REP PF05086.7 GAP91723.1 - 0.82 7.3 2.9 0.89 7.2 2.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sporozoite_P67 PF05642.6 GAP91723.1 - 1.9 6.2 8.2 2.1 6.0 5.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Proteasome PF00227.21 GAP91724.1 - 1.4e-50 171.2 0.0 1.8e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 GAP91724.1 - 6.1e-12 44.6 0.3 1.2e-11 43.7 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Vps55 PF04133.9 GAP91725.1 - 2.2e-45 153.2 4.5 2.4e-45 153.1 3.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF2301 PF10063.4 GAP91725.1 - 0.26 11.4 3.1 0.55 10.4 0.3 2.0 2 0 0 2 2 2 0 Uncharacterized integral membrane protein (DUF2301) RabGAP-TBC PF00566.13 GAP91726.1 - 2.8e-35 121.7 3.6 7.4e-35 120.3 2.5 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 GAP91726.1 - 4.6e-11 42.4 0.0 1.4e-05 24.4 0.0 4.0 3 1 0 3 3 3 3 Domain of unknown function (DUF3548) Mso1_Sec1_bdg PF14475.1 GAP91727.1 - 4.4e-20 70.7 0.1 7.1e-20 70.1 0.0 1.3 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ribosomal_L28e PF01778.12 GAP91728.1 - 8e-29 100.4 0.2 8e-29 100.4 0.1 1.8 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 GAP91728.1 - 6.2e-19 67.9 48.6 8.2e-17 61.1 25.0 3.5 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.5 GAP91728.1 - 0.00059 19.0 22.1 0.00081 18.5 15.3 1.1 1 0 0 1 1 1 1 BUD22 UPF0066 PF01980.11 GAP91728.1 - 0.013 15.3 0.1 0.027 14.4 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0066 CENP-T PF15511.1 GAP91728.1 - 0.04 13.1 18.9 0.065 12.4 13.1 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 GAP91728.1 - 0.23 9.3 36.2 0.36 8.7 25.1 1.2 1 0 0 1 1 1 0 Nop14-like family TrmE_N PF10396.4 GAP91729.1 - 1.4e-35 121.7 0.0 3.5e-35 120.4 0.0 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 GAP91729.1 - 6.5e-19 68.1 0.0 2.3e-18 66.3 0.0 2.1 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 GAP91729.1 - 6.7e-16 58.2 0.0 1.3e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAP91729.1 - 0.00012 21.3 0.0 0.00024 20.4 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 GAP91729.1 - 0.00016 21.5 0.0 0.00037 20.3 0.0 1.7 1 1 0 1 1 1 1 Dynamin family ABC_tran PF00005.22 GAP91729.1 - 0.0092 16.2 0.0 0.029 14.6 0.0 1.8 1 1 1 2 2 2 1 ABC transporter DUF258 PF03193.11 GAP91729.1 - 0.052 12.7 0.0 0.12 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 GAP91729.1 - 0.061 12.7 0.0 2.1 7.7 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Miro PF08477.8 GAP91729.1 - 0.077 13.4 0.0 0.21 12.1 0.0 1.7 2 0 0 2 2 2 0 Miro-like protein Med6 PF04934.9 GAP91730.1 - 7.3e-43 145.4 0.0 9.7e-43 145.0 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component MMtag PF10159.4 GAP91731.1 - 1.3e-30 105.2 2.3 2.7e-30 104.2 1.6 1.5 1 0 0 1 1 1 1 Kinase phosphorylation protein DUF3684 PF12449.3 GAP91732.1 - 0 1308.3 0.0 0 1308.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 GAP91732.1 - 5.9e-05 22.7 0.0 0.00014 21.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Reprolysin_5 PF13688.1 GAP91732.1 - 0.13 12.2 0.0 0.35 10.7 0.0 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12 HA2 PF04408.18 GAP91733.1 - 4.7e-20 71.5 0.0 1.6e-19 69.7 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 GAP91733.1 - 3.4e-14 52.4 0.0 1.7e-13 50.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAP91733.1 - 2.4e-10 40.1 0.2 2e-08 33.9 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 GAP91733.1 - 1.8e-09 37.4 0.0 5.4e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Daxx PF03344.10 GAP91733.1 - 0.00049 18.7 7.2 0.00049 18.7 5.0 1.7 2 0 0 2 2 2 1 Daxx Family AAA_23 PF13476.1 GAP91733.1 - 0.0072 16.6 4.1 0.06 13.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 GAP91733.1 - 0.0091 16.1 0.0 0.03 14.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 GAP91733.1 - 0.0096 15.4 0.0 0.025 14.0 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family T2SE PF00437.15 GAP91733.1 - 0.023 13.6 0.0 0.058 12.2 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 GAP91733.1 - 0.025 14.9 0.1 0.81 9.9 0.0 2.6 2 0 0 2 2 2 0 ABC transporter Phage_G PF02306.10 GAP91733.1 - 0.025 14.2 0.1 0.049 13.2 0.1 1.4 1 0 0 1 1 1 0 Major spike protein (G protein) AAA_29 PF13555.1 GAP91733.1 - 0.033 13.7 0.0 0.069 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 GAP91733.1 - 0.043 13.6 0.0 0.14 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 GAP91733.1 - 0.92 8.4 4.4 0.31 9.9 0.0 2.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) 2OG-FeII_Oxy PF03171.15 GAP91735.1 - 4.6e-22 78.1 0.0 8.8e-21 74.0 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 GAP91735.1 - 1.1e-20 74.2 0.0 1.9e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Cyclase PF04199.8 GAP91736.1 - 2e-07 30.8 0.0 2.9e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase HAD_2 PF13419.1 GAP91737.1 - 4.6e-13 49.7 0.0 6.1e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAP91737.1 - 2e-05 24.2 0.1 4.7e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 GAP91737.1 - 0.0014 19.0 0.0 0.0017 18.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Metallophos PF00149.23 GAP91738.1 - 2.8e-41 141.1 1.4 4.4e-41 140.4 0.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3322 PF11795.3 GAP91738.1 - 0.00023 20.8 0.5 0.00038 20.1 0.4 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria N-term (DUF3322) adh_short_C2 PF13561.1 GAP91739.1 - 5.4e-24 85.2 0.7 9.5e-24 84.4 0.5 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAP91739.1 - 2.1e-20 73.3 3.5 3.6e-20 72.5 2.4 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP91739.1 - 3.4e-07 30.1 1.6 8e-07 28.8 1.1 1.6 1 1 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 GAP91739.1 - 0.01 15.0 0.1 0.022 13.8 0.1 1.6 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 GAP91739.1 - 0.02 14.6 0.6 0.056 13.1 0.2 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus YjeF_N PF03853.10 GAP91739.1 - 0.04 13.5 0.2 0.06 12.9 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus 3HCDH_N PF02737.13 GAP91739.1 - 0.059 13.0 0.5 0.095 12.3 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 GAP91739.1 - 0.064 12.6 0.4 0.82 9.0 0.3 2.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 GAP91739.1 - 0.068 12.1 0.3 0.1 11.5 0.2 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase ApbA PF02558.11 GAP91739.1 - 0.071 12.5 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF3698 PF12479.3 GAP91739.1 - 0.077 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3698) TauD PF02668.11 GAP91740.1 - 5.4e-38 131.1 0.0 2.8e-37 128.7 0.0 1.8 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 GAP91740.1 - 0.00011 22.5 0.0 0.00024 21.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CCSMST1 PF15013.1 GAP91741.1 - 0.025 14.5 1.0 2 8.3 0.2 2.5 2 0 0 2 2 2 0 CCSMST1 family PhoD PF09423.5 GAP91742.1 - 8.6e-62 209.1 0.0 1.1e-61 208.7 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase EMP24_GP25L PF01105.19 GAP91743.1 - 8.3e-47 159.2 0.8 9.5e-47 159.0 0.6 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SKIP_SNW PF02731.10 GAP91744.1 - 9.5e-65 216.8 3.1 9.5e-65 216.8 2.1 2.3 2 0 0 2 2 2 1 SKIP/SNW domain DUF4603 PF15376.1 GAP91744.1 - 8.2 3.4 16.9 12 2.9 11.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) ubiquitin PF00240.18 GAP91745.1 - 0.00012 21.3 0.0 0.00021 20.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 GAP91745.1 - 0.00014 21.4 0.0 0.00036 20.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 GAP91745.1 - 0.014 15.5 0.1 0.04 14.0 0.0 1.8 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain DUF4141 PF13605.1 GAP91745.1 - 0.059 12.5 0.1 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) RVT_1 PF00078.22 GAP91746.1 - 8e-05 22.0 0.0 0.00016 21.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PBP1_TM PF14812.1 GAP91747.1 - 6.1e-07 29.6 13.2 6.3e-07 29.6 0.6 2.3 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Spt5_N PF11942.3 GAP91747.1 - 0.00012 22.5 7.6 0.00021 21.8 5.3 1.3 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal Plasmodium_Vir PF05795.6 GAP91747.1 - 0.00029 20.1 0.0 0.00037 19.7 0.0 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein CDC45 PF02724.9 GAP91747.1 - 0.00054 18.1 3.5 0.00074 17.6 2.4 1.1 1 0 0 1 1 1 1 CDC45-like protein Syndecan PF01034.15 GAP91747.1 - 0.0047 16.5 0.3 0.01 15.4 0.2 1.5 1 0 0 1 1 1 1 Syndecan domain DUF2457 PF10446.4 GAP91747.1 - 0.0051 15.6 5.5 0.0051 15.6 3.8 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) Mid2 PF04478.7 GAP91747.1 - 0.011 15.1 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF1510 PF07423.6 GAP91747.1 - 0.015 14.6 0.0 0.015 14.6 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1510) Herpes_gE PF02480.11 GAP91747.1 - 0.015 13.5 0.3 0.042 12.1 0.2 1.6 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 GAP91747.1 - 0.016 13.9 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) SKG6 PF08693.5 GAP91747.1 - 0.021 14.1 2.8 0.051 12.8 1.9 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MLANA PF14991.1 GAP91747.1 - 0.021 14.8 0.1 0.058 13.4 0.1 1.7 1 1 0 1 1 1 0 Protein melan-A EphA2_TM PF14575.1 GAP91747.1 - 0.034 14.5 0.7 0.073 13.4 0.0 1.9 2 1 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain PgaD PF13994.1 GAP91747.1 - 0.035 13.5 0.2 0.057 12.8 0.1 1.3 1 0 0 1 1 1 0 PgaD-like protein TMEM51 PF15345.1 GAP91747.1 - 0.037 13.7 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 ATG22 PF11700.3 GAP91747.1 - 0.052 12.0 0.0 0.068 11.6 0.0 1.2 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Shisa PF13908.1 GAP91747.1 - 0.052 13.7 0.0 0.087 12.9 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF912 PF06024.7 GAP91747.1 - 0.052 13.5 0.5 0.27 11.3 0.0 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4381 PF14316.1 GAP91747.1 - 0.071 13.2 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) NicO PF03824.11 GAP91747.1 - 0.073 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein ATG27 PF09451.5 GAP91747.1 - 0.09 11.9 0.1 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 DUF2681 PF10883.3 GAP91747.1 - 0.11 12.7 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) HemY_N PF07219.8 GAP91747.1 - 0.11 12.0 0.2 0.24 10.9 0.1 1.5 1 0 0 1 1 1 0 HemY protein N-terminus DUF2076 PF09849.4 GAP91747.1 - 0.3 11.0 0.1 0.3 11.0 0.0 3.1 2 1 1 3 3 2 0 Uncharacterized protein conserved in bacteria (DUF2076) FAM176 PF14851.1 GAP91747.1 - 0.3 10.7 8.5 5.9 6.5 0.0 2.2 1 1 1 2 2 2 0 FAM176 family DUF1049 PF06305.6 GAP91747.1 - 0.31 10.5 6.4 0.12 11.8 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) TMEM154 PF15102.1 GAP91747.1 - 0.44 10.2 0.0 0.44 10.2 0.0 1.7 1 1 0 2 2 2 0 TMEM154 protein family Conotoxin PF02950.12 GAP91747.1 - 1.3 9.8 5.0 1.9 9.3 0.0 2.7 2 1 0 2 2 2 0 Conotoxin Nucleoplasmin PF03066.10 GAP91747.1 - 1.4 8.4 11.8 0.04 13.4 4.0 1.5 2 0 0 2 2 1 0 Nucleoplasmin UPF0560 PF10577.4 GAP91747.1 - 1.4 7.0 5.8 16 3.6 3.7 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 Myc_N PF01056.13 GAP91747.1 - 4.4 6.3 6.8 0.19 10.8 0.7 1.6 2 0 0 2 2 1 0 Myc amino-terminal region RXT2_N PF08595.6 GAP91747.1 - 4.9 6.9 11.0 5.1 6.8 4.4 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal GRP PF07172.6 GAP91747.1 - 8.4 6.9 20.8 0.4 11.1 0.1 2.7 2 1 0 2 2 1 0 Glycine rich protein family TPR_17 PF13431.1 GAP91748.1 - 1.5e-05 24.7 0.3 6.7 7.1 0.0 4.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 GAP91748.1 - 0.00013 21.5 12.1 0.1 12.2 1.2 4.7 5 1 0 5 5 5 3 TPR repeat TPR_14 PF13428.1 GAP91748.1 - 0.00013 22.2 7.0 0.24 12.1 1.9 4.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAP91748.1 - 0.0037 17.5 4.9 9.4 6.6 0.7 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAP91748.1 - 0.18 12.5 8.7 4.4 8.1 2.9 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.5 GAP91749.1 - 1.8e-157 524.2 0.0 2.3e-157 523.8 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.1 GAP91749.1 - 2.7e-08 33.7 1.1 0.5 11.1 0.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAP91749.1 - 6.4e-07 28.9 1.0 0.064 12.9 0.2 3.8 4 0 0 4 4 4 2 TPR repeat TPR_7 PF13176.1 GAP91749.1 - 8.4e-06 25.2 2.1 0.16 11.8 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAP91749.1 - 1.2e-05 25.5 0.8 0.0073 16.6 0.0 3.0 2 1 1 3 3 2 1 Tetratricopeptide repeat Apc3 PF12895.2 GAP91749.1 - 1.3e-05 25.2 0.5 0.053 13.6 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 GAP91749.1 - 4.9e-05 23.8 1.1 2 9.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAP91749.1 - 7e-05 22.4 6.8 0.29 11.1 2.8 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAP91749.1 - 0.0002 21.1 1.1 0.1 12.4 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAP91749.1 - 0.00041 19.9 0.5 1.2 9.0 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAP91749.1 - 0.0016 18.3 0.9 2.5 8.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAP91749.1 - 0.004 16.6 1.4 3.5 7.3 0.8 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 GAP91749.1 - 0.0048 16.0 2.5 0.13 11.3 0.7 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat PPR_3 PF13812.1 GAP91749.1 - 0.022 14.9 0.0 26 5.4 0.0 3.7 3 0 0 3 3 3 0 Pentatricopeptide repeat domain TPR_6 PF13174.1 GAP91749.1 - 0.037 14.4 2.0 39 5.0 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2007 PF09413.5 GAP91749.1 - 0.042 13.6 0.0 0.29 10.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2007) Zn_clus PF00172.13 GAP91750.1 - 2.2e-08 33.8 10.5 3.3e-08 33.2 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AdoHcyase PF05221.12 GAP91751.1 - 2.4e-139 462.7 0.2 2.8e-139 462.5 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 GAP91751.1 - 1e-83 279.0 1.8 1.8e-83 278.2 1.2 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 GAP91751.1 - 1.7e-07 30.5 0.1 3.6e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 GAP91751.1 - 0.00074 18.9 0.2 0.0013 18.0 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain ELFV_dehydrog PF00208.16 GAP91751.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.13 GAP91751.1 - 0.052 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain JAB PF01398.16 GAP91752.1 - 3.4e-08 33.2 0.4 1.5e-06 27.8 0.3 2.5 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Phage_XkdX PF09693.5 GAP91752.1 - 0.13 11.8 0.3 1.7 8.2 0.1 2.4 2 0 0 2 2 2 0 Phage uncharacterised protein (Phage_XkdX) K-box PF01486.12 GAP91754.1 - 0.0015 18.2 0.4 0.67 9.7 0.0 2.6 2 0 0 2 2 2 2 K-box region DivIC PF04977.10 GAP91754.1 - 0.0018 17.6 0.1 0.0018 17.6 0.1 2.3 4 0 0 4 4 4 1 Septum formation initiator DUF1875 PF08961.5 GAP91754.1 - 0.048 12.9 0.0 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1875) IncA PF04156.9 GAP91754.1 - 0.11 12.0 1.9 0.081 12.5 0.2 1.6 2 0 0 2 2 2 0 IncA protein TMF_DNA_bd PF12329.3 GAP91754.1 - 0.14 11.9 2.8 0.33 10.7 0.7 2.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Hemerythrin PF01814.18 GAP91754.1 - 0.19 11.9 1.6 0.34 11.0 0.4 1.9 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain DUF4140 PF13600.1 GAP91754.1 - 0.28 11.6 7.3 0.74 10.2 1.2 3.1 2 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) TMF_TATA_bd PF12325.3 GAP91754.1 - 8 6.2 7.7 15 5.3 1.4 2.7 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Tic20 PF09685.5 GAP91755.1 - 3.4e-07 30.2 1.2 4.4e-07 29.8 0.8 1.1 1 0 0 1 1 1 1 Tic20-like protein Pex14_N PF04695.8 GAP91755.1 - 0.029 14.4 4.9 0.055 13.5 3.4 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Retinal PF15449.1 GAP91755.1 - 1.9 6.0 9.4 2.3 5.7 6.5 1.0 1 0 0 1 1 1 0 Retinal protein Ribosomal_L10 PF00466.15 GAP91756.1 - 0.0071 16.2 0.1 0.093 12.6 0.0 2.6 3 1 0 3 3 3 1 Ribosomal protein L10 Glycos_transf_3 PF00591.16 GAP91757.1 - 3.5e-63 213.3 0.0 4.9e-63 212.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 GAP91757.1 - 9.9e-10 37.8 0.0 9.9e-10 37.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain RNA_lig_T4_1 PF09511.5 GAP91758.1 - 5.5e-81 271.2 0.0 9.6e-81 270.4 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.6 GAP91758.1 - 1.7e-76 256.8 0.0 2.3e-76 256.4 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.6 GAP91758.1 - 1.8e-56 190.6 2.9 4.6e-55 186.0 0.4 2.4 2 0 0 2 2 2 2 tRNA ligase kinase domain SPOUT_MTase PF02590.12 GAP91758.1 - 0.022 14.4 0.5 0.074 12.7 0.3 1.9 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase Ribonuc_P_40 PF08584.6 GAP91759.1 - 2e-55 187.8 0.0 2.4e-54 184.2 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit UPF0020 PF01170.13 GAP91760.1 - 8.3e-11 41.7 0.0 1.5e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 GAP91760.1 - 3e-09 36.9 0.0 6.1e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MethyltransfD12 PF02086.10 GAP91760.1 - 0.079 12.4 0.0 0.31 10.4 0.0 2.0 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase Vac_ImportDeg PF09783.4 GAP91761.1 - 5.3e-68 227.9 2.5 7.2e-68 227.5 1.7 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mago_nashi PF02792.9 GAP91762.1 - 1.3e-74 248.6 0.2 1.5e-74 248.4 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein Beta-lactamase PF00144.19 GAP91764.1 - 2.1e-38 132.1 0.2 7.6e-38 130.3 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase Pyr_redox_3 PF13738.1 GAP91765.1 - 1.9e-22 80.3 0.0 2.9e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAP91765.1 - 2.7e-19 68.7 0.5 1.6e-15 56.3 0.0 2.4 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 GAP91765.1 - 7.1e-10 39.0 0.0 1.8e-09 37.7 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAP91765.1 - 1.5e-09 37.2 0.0 4.6e-09 35.6 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 GAP91765.1 - 4e-07 29.9 1.3 2.7e-06 27.2 0.0 3.0 3 1 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAP91765.1 - 1.2e-06 27.6 0.1 0.0063 15.4 0.0 3.0 3 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAP91765.1 - 0.0061 16.3 4.3 15 5.3 0.0 4.1 4 0 0 4 4 4 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 GAP91765.1 - 0.0072 15.2 0.0 0.02 13.8 0.0 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAP91765.1 - 0.012 14.5 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 GAP91765.1 - 0.014 15.7 0.2 2.4 8.6 0.1 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAP91765.1 - 0.096 11.1 1.7 0.16 10.4 0.0 2.1 3 0 0 3 3 3 0 HI0933-like protein Thi4 PF01946.12 GAP91765.1 - 0.13 11.3 0.1 0.37 9.8 0.0 1.7 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.17 GAP91765.1 - 0.26 10.1 0.8 9.8 4.9 0.0 2.9 3 1 0 3 3 3 0 Glucose inhibited division protein A HEAT_2 PF13646.1 GAP91766.1 - 8.5e-20 70.8 8.3 4.8e-06 26.7 0.3 5.8 5 0 0 5 5 5 4 HEAT repeats NACHT PF05729.7 GAP91766.1 - 7.6e-16 58.2 0.8 3.1e-15 56.2 0.0 2.5 3 0 0 3 3 3 1 NACHT domain HEAT_EZ PF13513.1 GAP91766.1 - 1.5e-08 34.9 7.4 0.00012 22.4 0.3 5.4 5 0 0 5 5 5 2 HEAT-like repeat HEAT PF02985.17 GAP91766.1 - 2.8e-06 26.9 3.3 0.012 15.6 0.1 5.1 5 0 0 5 5 4 1 HEAT repeat AAA_22 PF13401.1 GAP91766.1 - 0.00043 20.4 0.1 0.016 15.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 GAP91766.1 - 0.00045 21.0 0.0 0.0039 17.9 0.0 2.8 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 GAP91766.1 - 0.0019 17.1 0.0 0.0039 16.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Adaptin_N PF01602.15 GAP91766.1 - 0.0025 16.2 0.3 0.2 9.9 0.0 2.8 3 0 0 3 3 3 1 Adaptin N terminal region DNA_alkylation PF08713.6 GAP91766.1 - 0.0053 16.2 0.0 4.3 6.7 0.0 3.4 2 1 0 2 2 2 1 DNA alkylation repair enzyme AAA_16 PF13191.1 GAP91766.1 - 0.007 16.3 5.8 0.02 14.9 0.0 4.1 3 2 2 5 5 5 1 AAA ATPase domain Arm PF00514.18 GAP91766.1 - 0.0092 15.7 0.7 9.7 6.1 0.0 3.5 3 0 0 3 3 2 0 Armadillo/beta-catenin-like repeat MobB PF03205.9 GAP91766.1 - 0.012 15.2 0.0 0.41 10.3 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 GAP91766.1 - 0.019 15.2 0.3 0.19 12.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF1678 PF07913.6 GAP91766.1 - 0.046 13.2 0.4 1.6 8.2 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1678) AAA_14 PF13173.1 GAP91766.1 - 0.063 13.1 0.0 0.2 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 GAP91766.1 - 0.073 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 NTPase Cohesin_HEAT PF12765.2 GAP91766.1 - 0.13 12.2 3.1 13 5.8 0.3 4.0 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion RNA_helicase PF00910.17 GAP91766.1 - 0.15 12.2 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Adaptin_N PF01602.15 GAP91768.1 - 1.4e-93 314.0 8.7 2.3e-93 313.3 6.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.7 GAP91768.1 - 1.9e-63 212.3 0.7 3.9e-63 211.2 0.5 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.1 GAP91768.1 - 7e-63 210.1 0.0 2e-62 208.6 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.1 GAP91768.1 - 4.9e-11 42.7 6.7 1.2e-07 31.9 0.0 4.2 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.2 GAP91768.1 - 1.1e-05 25.4 7.5 0.00074 19.4 0.0 4.1 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 GAP91768.1 - 0.0035 17.3 0.2 2 8.7 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 GAP91768.1 - 0.042 14.3 4.0 1.4 9.5 0.0 4.4 4 1 1 5 5 5 0 HEAT-like repeat DUF3824 PF12868.2 GAP91769.1 - 0.003 18.4 4.1 0.003 18.4 2.8 1.4 1 1 0 1 1 1 1 Domain of unknwon function (DUF3824) COX14 PF14880.1 GAP91769.1 - 0.16 11.6 0.8 0.24 11.0 0.6 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c assembly ATP-synt_E PF05680.7 GAP91769.1 - 0.22 11.5 5.1 0.36 10.8 3.5 1.4 1 1 0 1 1 1 0 ATP synthase E chain Aldo_ket_red PF00248.16 GAP91770.1 - 5.3e-50 169.8 0.0 6.3e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HIT PF01230.18 GAP91771.1 - 2.8e-18 66.2 0.0 3.9e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 GAP91771.1 - 5.7e-09 36.2 0.0 9.9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CobT PF06213.7 GAP91771.1 - 0.017 14.2 10.5 0.029 13.4 7.3 1.4 1 1 0 1 1 1 0 Cobalamin biosynthesis protein CobT CwfJ_C_1 PF04677.10 GAP91771.1 - 0.041 13.5 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 Glypican PF01153.14 GAP91771.1 - 0.05 12.2 0.5 0.056 12.0 0.4 1.1 1 0 0 1 1 1 0 Glypican Phage_portal_2 PF05136.8 GAP91771.1 - 0.18 10.2 2.9 0.21 10.0 0.7 1.8 2 0 0 2 2 2 0 Phage portal protein, lambda family Nucleoplasmin PF03066.10 GAP91771.1 - 0.2 11.1 10.3 0.31 10.5 7.2 1.2 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 GAP91771.1 - 1.4 8.0 6.2 1.9 7.7 4.3 1.1 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 GAP91771.1 - 1.9 6.3 12.0 2.3 6.0 8.3 1.0 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 GAP91771.1 - 3.4 7.2 10.9 4.8 6.7 7.5 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 GAP91771.1 - 9.9 4.0 7.9 13 3.7 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_RNApol_7kD PF03604.8 GAP91772.1 - 2e-14 52.7 8.6 2.6e-14 52.3 6.0 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DUF2082 PF09855.4 GAP91772.1 - 0.0046 16.7 2.3 1.5 8.7 0.4 2.2 1 1 1 2 2 2 2 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) HypA PF01155.14 GAP91772.1 - 0.01 15.4 0.8 0.012 15.2 0.5 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family TF_Zn_Ribbon PF08271.7 GAP91772.1 - 0.015 14.5 2.3 0.84 9.0 0.1 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding TFIIS_C PF01096.13 GAP91772.1 - 0.031 13.8 3.3 0.32 10.6 0.0 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) GFA PF04828.9 GAP91772.1 - 0.045 13.7 2.5 2.3 8.1 0.4 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-C3HC PF07967.8 GAP91772.1 - 0.052 13.3 0.3 0.055 13.2 0.2 1.1 1 0 0 1 1 1 0 C3HC zinc finger-like Prok-RING_1 PF14446.1 GAP91772.1 - 0.078 12.7 1.8 0.11 12.2 1.2 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 A2L_zn_ribbon PF08792.5 GAP91772.1 - 0.38 10.2 4.0 3.4 7.2 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.5 GAP91772.1 - 0.43 10.5 4.9 0.98 9.4 3.4 1.6 1 1 0 1 1 1 0 Zinc ribbon domain zf-C2H2 PF00096.21 GAP91772.1 - 0.61 10.5 4.1 1.6 9.2 0.2 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type Zn_ribbon_recom PF13408.1 GAP91772.1 - 5.7 7.2 8.6 11 6.3 1.9 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Auto_anti-p27 PF06677.7 GAP91772.1 - 7.6 6.3 7.0 19 5.1 0.3 2.1 1 1 1 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) ATP_bind_1 PF03029.12 GAP91773.1 - 1.6e-74 250.4 0.0 2.3e-74 249.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 GAP91773.1 - 2.2e-05 23.4 0.5 0.012 14.3 0.0 2.4 2 1 0 2 2 2 2 ArgK protein GTP_EFTU PF00009.22 GAP91773.1 - 3.6e-05 23.2 0.1 0.0021 17.5 0.1 2.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 GAP91773.1 - 0.00024 21.2 0.0 0.0008 19.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 GAP91773.1 - 0.00033 20.5 0.0 0.00092 19.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAP91773.1 - 0.00042 20.8 0.1 0.37 11.2 0.0 2.6 3 0 0 3 3 2 1 Miro-like protein AAA_16 PF13191.1 GAP91773.1 - 0.00068 19.6 0.0 0.0013 18.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 GAP91773.1 - 0.00092 18.3 0.0 0.0019 17.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Arf PF00025.16 GAP91773.1 - 0.0012 18.1 0.0 1 8.5 0.0 3.0 2 1 0 2 2 2 1 ADP-ribosylation factor family AAA_30 PF13604.1 GAP91773.1 - 0.0013 18.3 0.1 0.0028 17.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAP91773.1 - 0.0014 18.4 0.0 0.003 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAP91773.1 - 0.0018 19.1 0.2 0.0059 17.4 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_10 PF12846.2 GAP91773.1 - 0.0024 17.3 0.4 0.0093 15.4 0.3 2.0 1 1 0 1 1 1 1 AAA-like domain FeoB_N PF02421.13 GAP91773.1 - 0.0029 16.8 0.0 0.08 12.2 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B NACHT PF05729.7 GAP91773.1 - 0.003 17.2 0.0 0.0082 15.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain G-alpha PF00503.15 GAP91773.1 - 0.0058 15.3 0.5 0.22 10.1 0.0 2.5 3 0 0 3 3 3 1 G-protein alpha subunit NB-ARC PF00931.17 GAP91773.1 - 0.0066 15.3 0.7 0.017 14.0 0.1 1.9 2 0 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.1 GAP91773.1 - 0.0095 15.5 0.0 0.1 12.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 GAP91773.1 - 0.011 15.1 0.0 0.13 11.6 0.0 2.4 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain cobW PF02492.14 GAP91773.1 - 0.025 14.0 0.0 0.59 9.5 0.0 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 GAP91773.1 - 0.036 13.8 0.1 0.072 12.8 0.1 1.4 1 0 0 1 1 1 0 Part of AAA domain PduV-EutP PF10662.4 GAP91773.1 - 0.039 13.4 0.1 0.73 9.3 0.0 2.7 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 GAP91773.1 - 0.045 13.4 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B LcrG PF07216.7 GAP91773.1 - 0.046 13.7 0.5 0.097 12.7 0.4 1.5 1 0 0 1 1 1 0 LcrG protein PRK PF00485.13 GAP91773.1 - 0.087 12.3 0.0 0.31 10.5 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family BTB PF00651.26 GAP91774.1 - 4.7e-08 33.0 0.0 1.1e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Pkinase PF00069.20 GAP91775.1 - 1.6e-06 27.4 0.0 3.2e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 GAP91775.1 - 0.05 13.3 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Abhydrolase_6 PF12697.2 GAP91777.1 - 1.7e-10 41.1 0.0 2.1e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAP91777.1 - 2.6e-07 30.0 0.0 4.1e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAP91777.1 - 7e-07 29.1 0.0 1.2e-06 28.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 GAP91777.1 - 6.2e-05 22.5 0.0 9.4e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 GAP91777.1 - 6.6e-05 21.5 0.1 0.0001 20.9 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 GAP91777.1 - 0.00077 19.2 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 GAP91777.1 - 0.0025 17.4 0.0 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 GAP91777.1 - 0.0081 15.4 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.3 GAP91777.1 - 0.021 14.6 0.0 0.051 13.4 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase p450 PF00067.17 GAP91778.1 - 2.5e-52 177.9 0.0 3.2e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 2OG-FeII_Oxy PF03171.15 GAP91779.1 - 9.8e-12 45.0 0.0 2.3e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 GAP91779.1 - 4.4e-11 43.3 0.0 9.2e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DIOX_N PF14226.1 GAP91780.1 - 2.7e-23 82.7 0.0 4.8e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAP91780.1 - 2.2e-20 72.8 0.0 3.7e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2507 PF10702.4 GAP91782.1 - 0.13 11.9 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2507) NB-ARC PF00931.17 GAP91783.1 - 6e-19 67.9 0.0 1e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain DUF676 PF05057.9 GAP91783.1 - 3.2e-07 29.8 0.0 6.5e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) TPR_12 PF13424.1 GAP91783.1 - 5.4e-07 29.4 0.3 0.00049 19.9 0.0 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat Apc3 PF12895.2 GAP91783.1 - 2.6e-06 27.4 4.5 0.0018 18.3 0.4 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 PGAP1 PF07819.8 GAP91783.1 - 1.7e-05 24.5 0.0 5.7e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein TPR_10 PF13374.1 GAP91783.1 - 2.4e-05 24.0 0.1 1 9.4 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 GAP91783.1 - 0.00023 21.1 0.1 0.00054 19.9 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_16 PF13191.1 GAP91783.1 - 0.00074 19.5 0.0 0.014 15.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 GAP91783.1 - 0.0014 18.2 0.2 0.0094 15.6 0.0 2.5 3 1 0 3 3 3 1 NACHT domain TPR_19 PF14559.1 GAP91783.1 - 0.0018 18.5 2.1 1.1 9.6 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF829 PF05705.9 GAP91783.1 - 0.0022 17.7 0.0 0.0049 16.5 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) IstB_IS21 PF01695.12 GAP91783.1 - 0.023 14.1 0.1 0.051 12.9 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.1 GAP91783.1 - 0.061 13.4 0.0 0.48 10.5 0.0 2.4 3 0 0 3 3 3 0 AAA domain Eno-Rase_NADH_b PF12242.3 GAP91783.1 - 0.063 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Abhydrolase_5 PF12695.2 GAP91783.1 - 0.067 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family ArsA_ATPase PF02374.10 GAP91783.1 - 0.077 12.0 0.1 0.13 11.2 0.1 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase Torsin PF06309.6 GAP91783.1 - 0.14 12.0 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 Torsin TPR_2 PF07719.12 GAP91783.1 - 0.62 10.1 7.9 1.2 9.2 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAP91783.1 - 0.72 9.5 3.6 8.6 6.1 0.1 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat Peptidase_S24 PF00717.18 GAP91784.1 - 2.1e-06 27.2 0.0 4.1e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like TFIIB PF00382.14 GAP91785.1 - 8.2e-25 86.4 0.1 4.8e-18 64.7 0.0 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 GAP91785.1 - 2e-20 72.8 0.7 2e-20 72.8 0.5 2.6 2 0 0 2 2 2 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 GAP91785.1 - 0.00025 20.5 0.2 0.48 9.9 0.0 2.5 1 1 0 2 2 2 2 Cyclin, N-terminal domain Ribosomal_60s PF00428.14 GAP91785.1 - 0.0062 16.9 1.8 0.0062 16.9 1.3 3.4 4 0 0 4 4 4 1 60s Acidic ribosomal protein CwfJ_C_1 PF04677.10 GAP91786.1 - 7.8e-31 106.2 0.0 1.5e-30 105.3 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 GAP91786.1 - 2.4e-22 79.2 0.0 8.3e-22 77.5 0.0 2.0 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Brix PF04427.13 GAP91787.1 - 4.3e-32 111.3 0.1 5.7e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Brix domain DUF1765 PF08578.5 GAP91788.1 - 1.8e-43 147.6 9.5 3.1e-43 146.8 6.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Sfi1 PF08457.5 GAP91788.1 - 0.16 10.3 0.9 0.24 9.7 0.6 1.1 1 0 0 1 1 1 0 Sfi1 spindle body protein MFS_1 PF07690.11 GAP91789.1 - 1.1e-25 90.0 30.4 1.1e-25 90.0 21.1 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 GAP91790.1 - 5.2e-08 32.6 10.1 8.6e-08 31.9 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAP91790.1 - 0.0015 17.1 0.5 0.0025 16.4 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_92 PF07971.7 GAP91791.1 - 7.5e-150 499.8 0.8 9.8e-150 499.5 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 DPBB_1 PF03330.13 GAP91792.1 - 1.4e-11 44.2 0.1 1.9e-11 43.8 0.1 1.2 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 GAP91792.1 - 1.6e-05 24.5 0.1 1.9e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Barwin family Cerato-platanin PF07249.7 GAP91792.1 - 0.0001 22.3 0.4 0.00014 21.8 0.3 1.3 1 1 0 1 1 1 1 Cerato-platanin Lipocalin_5 PF13924.1 GAP91793.1 - 3.3e-07 30.0 0.0 3.9e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain Glyco_hydro_3 PF00933.16 GAP91794.1 - 7.8e-60 202.3 0.0 1.1e-59 201.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAP91794.1 - 2.3e-43 148.3 0.9 3.4e-43 147.7 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAP91794.1 - 0.0051 16.7 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain FAD_binding_4 PF01565.18 GAP91795.1 - 7.6e-21 74.0 0.5 1.9e-20 72.7 0.3 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP91795.1 - 2.1e-10 40.3 0.0 4.7e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 GAP91795.1 - 0.072 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding TAFA PF12020.3 GAP91796.1 - 0.019 15.0 0.7 0.041 13.9 0.5 1.6 1 0 0 1 1 1 0 TAFA family Zn_clus PF00172.13 GAP91797.1 - 5.9e-06 26.0 9.4 9.6e-06 25.4 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAP91797.1 - 1.3e-05 24.0 0.6 1.3e-05 24.0 0.4 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Glyco_hydro_3 PF00933.16 GAP91798.1 - 1.9e-89 299.6 0.0 2.7e-89 299.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAP91798.1 - 5.3e-49 166.7 0.3 2e-48 164.8 0.0 2.1 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAP91798.1 - 3.9e-19 68.3 0.0 7.3e-19 67.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain FAD_binding_4 PF01565.18 GAP91799.1 - 1.2e-21 76.5 2.9 2.8e-21 75.4 2.0 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP91799.1 - 1.3e-07 31.3 0.0 2.5e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 GAP91799.1 - 0.25 10.4 0.0 0.37 9.8 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding DUF1996 PF09362.5 GAP91800.1 - 1.3e-63 214.8 3.7 5.2e-48 163.7 0.1 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1996) Phosphodiest PF01663.17 GAP91802.1 - 4e-87 292.8 0.5 5.3e-87 292.4 0.3 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 GAP91802.1 - 0.00044 19.5 0.0 0.013 14.6 0.0 2.2 2 0 0 2 2 2 1 Sulfatase PglZ PF08665.7 GAP91802.1 - 0.02 14.5 0.1 0.1 12.2 0.0 2.1 2 0 0 2 2 2 0 PglZ domain YwiC PF14256.1 GAP91802.1 - 0.12 12.4 0.4 0.21 11.6 0.3 1.3 1 0 0 1 1 1 0 YwiC-like protein Lipase_2 PF01674.13 GAP91803.1 - 6.1e-10 38.7 0.0 4.6e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 Lipase (class 2) Abhydrolase_5 PF12695.2 GAP91803.1 - 6.2e-08 32.5 1.6 9.1e-08 31.9 1.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP91803.1 - 6.5e-08 32.7 7.5 1.1e-07 31.9 4.6 1.9 1 1 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 GAP91803.1 - 0.0049 16.1 0.0 0.0082 15.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DAGAT PF03982.8 GAP91803.1 - 0.12 11.0 0.0 0.24 10.0 0.0 1.4 1 1 0 1 1 1 0 Diacylglycerol acyltransferase Pec_lyase_C PF00544.14 GAP91805.1 - 3.2e-18 65.9 6.5 7.4e-18 64.7 4.5 1.6 1 1 0 1 1 1 1 Pectate lyase FAD_binding_4 PF01565.18 GAP91808.1 - 1.9e-17 63.0 4.1 2.3e-09 36.8 0.1 2.6 1 1 1 2 2 2 2 FAD binding domain BBE PF08031.7 GAP91808.1 - 7.4e-11 41.7 0.2 2.1e-10 40.3 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like DUF3954 PF13128.1 GAP91809.1 - 0.16 11.4 0.2 1.9 7.9 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3954) E1-E2_ATPase PF00122.15 GAP91810.1 - 9.1e-69 230.9 0.0 9.1e-69 230.9 0.0 2.2 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.21 GAP91810.1 - 1.7e-24 87.4 0.0 3.6e-24 86.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAP91810.1 - 9.2e-13 48.7 0.0 2.3e-12 47.5 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAP91810.1 - 3.7e-09 35.9 0.0 8.1e-09 34.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 GAP91810.1 - 0.0014 18.2 0.1 0.0031 17.1 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAP91810.1 - 0.05 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit GNVR PF13807.1 GAP91810.1 - 0.055 13.2 0.0 0.2 11.4 0.0 2.0 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase DMA PF03474.9 GAP91810.1 - 0.088 12.6 0.3 4.4 7.2 0.0 2.9 3 0 0 3 3 3 0 DMRTA motif adh_short_C2 PF13561.1 GAP91811.1 - 1.2e-25 90.6 0.0 1.6e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAP91811.1 - 3.4e-20 72.6 0.4 5.3e-20 71.9 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP91811.1 - 6.3e-11 42.2 0.2 1e-10 41.5 0.2 1.2 1 0 0 1 1 1 1 KR domain Catalase-rel PF06628.7 GAP91812.1 - 0.017 14.9 0.1 0.037 13.8 0.1 1.5 1 0 0 1 1 1 0 Catalase-related immune-responsive DUF3245 PF11595.3 GAP91813.1 - 0.13 12.5 4.5 0.25 11.5 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) PHD PF00628.24 GAP91814.1 - 5.6e-11 41.9 2.4 1.5e-10 40.5 1.7 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 GAP91814.1 - 0.13 11.6 3.3 0.24 10.7 2.3 1.4 1 0 0 1 1 1 0 PHD-finger UIM PF02809.15 GAP91814.1 - 0.53 10.0 5.0 0.099 12.2 0.4 2.2 2 0 0 2 2 2 0 Ubiquitin interaction motif MMR_HSR1 PF01926.18 GAP91815.1 - 2e-11 43.8 0.0 3.9e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 GAP91815.1 - 0.00086 19.1 0.1 0.1 12.4 0.0 2.3 2 0 0 2 2 2 1 Dynamin family IIGP PF05049.8 GAP91815.1 - 0.014 14.1 0.1 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF1127 PF06568.6 GAP91815.1 - 0.021 14.2 0.6 0.021 14.2 0.4 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1127) FeoB_N PF02421.13 GAP91815.1 - 0.024 13.8 0.5 0.048 12.9 0.1 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF258 PF03193.11 GAP91815.1 - 0.045 12.9 0.0 0.11 11.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 GAP91815.1 - 0.05 13.1 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 GAP91815.1 - 0.14 12.9 0.6 0.63 10.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain Arf PF00025.16 GAP91815.1 - 0.15 11.2 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family adh_short PF00106.20 GAP91816.1 - 5.6e-13 49.1 0.0 2.9e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 GAP91816.1 - 7.6e-05 22.5 0.0 0.00024 20.9 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP91816.1 - 0.0042 16.7 0.0 2.2 7.8 0.0 2.6 3 0 0 3 3 3 2 KR domain HET PF06985.6 GAP91820.1 - 4.8e-19 68.8 5.7 5.8e-16 58.9 0.4 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MaoC_dehydratas PF01575.14 GAP91821.1 - 0.0062 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain TonB_2 PF13103.1 GAP91822.1 - 0.13 12.2 0.2 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 TonB C terminal Pkinase PF00069.20 GAP91823.1 - 1.6e-14 53.7 0.0 3.4e-14 52.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 GAP91824.1 - 1.1e-17 64.0 0.0 2.3e-17 63.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP91824.1 - 6.9e-07 28.6 0.0 1.8e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 GAP91824.1 - 0.00047 19.0 0.0 0.00073 18.4 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.15 GAP91824.1 - 0.026 14.0 0.1 0.045 13.3 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Prok-RING_2 PF14445.1 GAP91824.1 - 0.12 12.3 0.0 9.4 6.2 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 APH PF01636.18 GAP91824.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family ATP-synt_ab_N PF02874.18 GAP91825.1 - 0.069 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, beta-barrel domain AflR PF08493.5 GAP91827.1 - 2.1e-09 36.8 0.0 3.4e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Aflatoxin regulatory protein Pkinase PF00069.20 GAP91828.1 - 5.2e-58 196.2 0.0 7.3e-58 195.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP91828.1 - 1.2e-36 126.1 0.0 4.9e-26 91.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAP91828.1 - 8.4e-05 21.6 0.0 0.00014 20.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like NCA2 PF08637.5 GAP91828.1 - 0.0047 15.8 0.0 0.016 14.0 0.0 1.8 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 Mid2 PF04478.7 GAP91829.1 - 0.0093 15.3 0.9 0.0093 15.3 0.7 2.6 1 1 2 3 3 3 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 GAP91829.1 - 0.047 13.0 0.8 0.047 13.0 0.6 2.9 3 0 0 3 3 3 0 Transmembrane alpha-helix domain Ndc1_Nup PF09531.5 GAP91829.1 - 0.35 9.2 3.5 0.39 9.0 2.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup THRAP3_BCLAF1 PF15440.1 GAP91829.1 - 2.2 6.8 13.2 3.4 6.2 9.1 1.2 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Menin PF05053.8 GAP91829.1 - 3.2 5.7 6.1 4.1 5.4 4.2 1.1 1 0 0 1 1 1 0 Menin DUF605 PF04652.11 GAP91829.1 - 5.3 6.3 26.0 8.2 5.7 18.0 1.3 1 0 0 1 1 1 0 Vta1 like Pex14_N PF04695.8 GAP91829.1 - 6.2 6.8 17.9 8.5e+02 -0.1 12.4 2.6 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3732 PF12532.3 GAP91830.1 - 0.14 11.6 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3732) Cerato-platanin PF07249.7 GAP91833.1 - 9.3e-56 186.9 2.0 1.1e-55 186.7 1.4 1.0 1 0 0 1 1 1 1 Cerato-platanin Peptidase_M64 PF09471.5 GAP91834.1 - 2.2e-26 93.0 0.0 3.7e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 IgA Peptidase M64 2-Hacid_dh_C PF02826.14 GAP91835.1 - 3.7e-53 179.2 0.0 5.6e-53 178.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAP91835.1 - 2e-29 101.7 0.1 2.6e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 GAP91835.1 - 0.00012 21.9 0.0 0.00039 20.3 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 GAP91835.1 - 0.0014 18.5 0.0 0.003 17.4 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Peripla_BP_3 PF13377.1 GAP91835.1 - 0.0077 16.2 1.3 0.037 14.0 0.2 2.4 3 0 0 3 3 3 1 Periplasmic binding protein-like domain IlvN PF07991.7 GAP91835.1 - 0.028 13.7 0.0 0.078 12.3 0.0 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF4440 PF14534.1 GAP91835.1 - 0.099 12.8 0.1 0.46 10.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) Pyr_redox PF00070.22 GAP91835.1 - 0.15 12.5 0.9 2.9 8.3 0.5 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MatE PF01554.13 GAP91836.1 - 3.6e-49 166.5 28.2 5.9e-29 100.7 7.6 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 GAP91836.1 - 1.1e-05 25.3 3.3 1.1e-05 25.3 2.3 4.2 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain MVIN PF03023.9 GAP91836.1 - 8.7e-05 21.1 6.7 8.7e-05 21.1 4.6 2.0 1 1 1 2 2 2 1 MviN-like protein Como_SCP PF02248.11 GAP91836.1 - 0.049 12.9 0.1 0.092 12.1 0.0 1.4 1 0 0 1 1 1 0 Small coat protein Aldo_ket_red PF00248.16 GAP91837.1 - 3.8e-33 114.5 0.0 1.4e-26 92.9 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family DUF1967 PF09269.6 GAP91837.1 - 0.14 11.7 0.0 0.39 10.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) DUF605 PF04652.11 GAP91839.1 - 0.088 12.1 1.8 0.077 12.3 1.2 1.2 1 0 0 1 1 1 0 Vta1 like DUF4577 PF15145.1 GAP91839.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) ATG27 PF09451.5 GAP91839.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Autophagy-related protein 27 PTCB-BRCT PF12738.2 GAP91841.1 - 3.1e-12 46.1 0.0 7.6e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 GAP91841.1 - 1.7e-11 44.1 0.0 3.4e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.16 GAP91841.1 - 0.0009 19.3 0.0 0.0024 17.9 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain RR_TM4-6 PF06459.7 GAP91841.1 - 5.1 6.9 8.8 7.6 6.3 6.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF-1a PF01176.14 GAP91843.1 - 5e-27 93.1 0.0 7.3e-27 92.5 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 WH1 PF00568.18 GAP91844.1 - 1.5e-26 92.2 0.2 2.2e-26 91.7 0.1 1.2 1 0 0 1 1 1 1 WH1 domain DUF2076 PF09849.4 GAP91844.1 - 7.5e-05 22.9 0.2 7.5e-05 22.9 0.1 3.6 3 2 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2076) WH2 PF02205.15 GAP91844.1 - 0.00058 19.3 0.2 0.0012 18.3 0.1 1.6 1 0 0 1 1 1 1 WH2 motif DUF3069 PF11269.3 GAP91844.1 - 0.071 13.1 0.2 0.15 12.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3069) Stm1_N PF09598.5 GAP91845.1 - 2 9.1 7.1 2.5 8.8 4.9 1.3 1 1 0 1 1 1 0 Stm1 ERCC4 PF02732.10 GAP91846.1 - 2.6e-26 92.1 0.0 6.7e-26 90.7 0.0 1.8 1 0 0 1 1 1 1 ERCC4 domain Glycoprotein_B PF00606.13 GAP91847.1 - 0.026 12.5 1.8 0.029 12.4 1.3 1.0 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B zf-C2H2_2 PF12756.2 GAP91847.1 - 0.048 13.7 0.0 0.06 13.4 0.0 1.1 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-CHCC PF10276.4 GAP91847.1 - 0.1 12.4 0.2 0.24 11.2 0.0 1.7 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2 PF00096.21 GAP91847.1 - 0.95 9.9 3.1 1.8 9.0 2.2 1.5 1 1 0 1 1 1 0 Zinc finger, C2H2 type Melibiase PF02065.13 GAP91849.1 - 1.7e-140 468.2 0.0 2.1e-140 467.9 0.0 1.1 1 0 0 1 1 1 1 Melibiase DUF187 PF02638.10 GAP91849.1 - 0.0015 17.4 0.0 0.004 16.0 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase like GH101 DUF1212 PF06738.7 GAP91851.1 - 1.8e-54 184.1 12.3 6.1e-51 172.6 0.3 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 GAP91851.1 - 7.5e-29 100.3 10.4 7.5e-29 100.3 7.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) adh_short PF00106.20 GAP91852.1 - 6.6e-18 65.1 6.1 1.2e-16 61.0 4.2 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP91852.1 - 3.4e-09 36.6 3.0 9.1e-07 28.7 0.1 2.3 1 1 0 2 2 2 2 KR domain NAD_binding_10 PF13460.1 GAP91852.1 - 1.4e-06 28.4 0.1 1.5e-05 25.0 0.1 2.1 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAP91852.1 - 0.0003 20.3 0.0 0.24 10.7 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAP91852.1 - 0.015 15.1 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.1 GAP91852.1 - 0.036 13.8 0.1 0.56 9.9 0.0 2.2 2 1 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.14 GAP91852.1 - 0.091 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.10 GAP91852.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Perilipin PF03036.11 GAP91853.1 - 8e-05 21.6 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 Perilipin family Reo_P9 PF06043.6 GAP91853.1 - 0.015 14.4 0.1 0.019 14.0 0.0 1.1 1 0 0 1 1 1 0 Reovirus P9-like family Spatacsin_C PF14649.1 GAP91854.1 - 0.89 8.3 4.7 0.28 10.0 0.5 1.8 1 1 1 2 2 2 0 Spatacsin C-terminus Pro_isomerase PF00160.16 GAP91856.1 - 1.2e-41 142.4 0.0 1.5e-41 142.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arrestin_C PF02752.17 GAP91857.1 - 2.1e-12 47.3 0.1 2.2e-11 44.0 0.1 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain tRNA_int_end_N2 PF12928.2 GAP91858.1 - 1.8e-17 62.5 0.0 3e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term XAP5 PF04921.9 GAP91859.1 - 6.9e-74 248.4 0.0 1.9e-73 246.9 0.0 1.6 1 1 1 2 2 2 1 XAP5, circadian clock regulator DUF1180 PF06679.7 GAP91859.1 - 0.35 10.7 6.8 12 5.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Fip1 PF05182.8 GAP91862.1 - 1.6e-20 72.0 1.2 3.5e-20 70.9 0.8 1.5 1 0 0 1 1 1 1 Fip1 motif Nucleoporin_FG PF13634.1 GAP91863.1 - 8.2e-16 58.2 85.6 2e-09 37.6 26.1 2.8 2 1 1 3 3 3 2 Nucleoporin FG repeat region DUF948 PF06103.6 GAP91863.1 - 0.13 12.1 1.5 3.8 7.4 0.1 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Prominin PF05478.6 GAP91863.1 - 0.29 8.6 0.8 0.8 7.1 0.0 1.8 2 0 0 2 2 2 0 Prominin MIP-T3 PF10243.4 GAP91864.1 - 0.7 8.2 20.1 0.97 7.8 14.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SAGA-Tad1 PF12767.2 GAP91864.1 - 1.4 8.5 14.6 2 8.0 10.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Fungal_trans_2 PF11951.3 GAP91865.1 - 0.00091 17.9 1.3 0.0011 17.7 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP91865.1 - 0.0065 16.3 4.9 0.014 15.2 3.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAP91867.1 - 1e-11 44.1 0.0 2e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP91867.1 - 1.7e-05 24.6 8.3 3.3e-05 23.7 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_10 PF05971.7 GAP91868.1 - 1e-59 202.1 0.0 1.5e-59 201.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) MTS PF05175.9 GAP91868.1 - 2.2e-07 30.4 0.0 4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 GAP91868.1 - 7e-07 29.8 0.0 2.7e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP91868.1 - 3e-06 27.2 0.0 6e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 GAP91868.1 - 0.00031 19.9 0.0 0.00055 19.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 GAP91868.1 - 0.00052 19.6 0.0 0.0015 18.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP91868.1 - 0.0074 16.7 0.0 0.017 15.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 GAP91868.1 - 0.048 13.2 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.7 GAP91868.1 - 0.091 13.2 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Herpes_LMP1 PF05297.6 GAP91868.1 - 0.098 11.5 0.7 0.14 11.0 0.5 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) SNO PF01174.14 GAP91869.1 - 2.3e-54 183.9 0.0 2.7e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 GAP91869.1 - 6e-11 42.1 0.0 3.8e-09 36.3 0.0 2.0 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.19 GAP91869.1 - 8e-05 22.1 0.0 0.0001 21.7 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 GAP91869.1 - 0.00023 20.6 0.0 0.00041 19.8 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DUF4066 PF13278.1 GAP91869.1 - 0.01 15.0 0.1 0.016 14.4 0.0 1.3 1 0 0 1 1 1 0 Putative amidotransferase Peptidase_S51 PF03575.12 GAP91869.1 - 0.099 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 SOR_SNZ PF01680.12 GAP91870.1 - 3.8e-104 346.7 6.1 5.3e-104 346.3 4.2 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 GAP91870.1 - 9.1e-08 31.4 8.8 7.2e-06 25.2 0.2 2.9 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 GAP91870.1 - 7.2e-05 22.1 0.1 0.0067 15.7 0.0 3.0 2 1 1 3 3 3 1 Histidine biosynthesis protein Dus PF01207.12 GAP91870.1 - 0.0015 17.4 0.3 0.49 9.1 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.9 GAP91870.1 - 0.0015 17.5 1.0 0.026 13.5 0.0 2.7 2 1 1 3 3 3 1 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.16 GAP91870.1 - 0.032 13.2 0.3 0.14 11.2 0.0 2.1 3 0 0 3 3 3 0 Indole-3-glycerol phosphate synthase Chaperone_III PF07824.7 GAP91870.1 - 0.11 12.4 0.1 2.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Type III secretion chaperone domain NMO PF03060.10 GAP91870.1 - 0.99 8.4 9.9 0.024 13.7 0.6 2.3 2 1 0 2 2 2 0 Nitronate monooxygenase Lipase_GDSL_2 PF13472.1 GAP91871.1 - 2.1e-09 37.7 5.5 3.7e-09 36.9 3.8 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAP91871.1 - 2.5e-08 34.0 0.4 4.1e-08 33.3 0.2 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PLDc PF00614.17 GAP91872.1 - 6.3e-16 57.5 1.1 2.4e-07 30.3 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 GAP91872.1 - 2.1e-14 53.3 0.5 8.9e-07 28.6 0.0 4.2 4 0 0 4 4 4 3 PLD-like domain GLTP PF08718.6 GAP91873.1 - 1.9e-44 151.3 0.0 2.7e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Glyco_hydro_61 PF03443.9 GAP91875.1 - 3.9e-65 219.7 0.4 4.5e-65 219.5 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PKD PF00801.15 GAP91875.1 - 1.6 8.5 4.9 5.4 6.8 0.5 2.6 1 1 1 2 2 2 0 PKD domain DUF1772 PF08592.6 GAP91876.1 - 1.8e-18 66.6 8.7 2.3e-18 66.2 6.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Beta-lactamase PF00144.19 GAP91877.1 - 9.9e-30 103.6 0.0 1.8e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase Acyltransferase PF01553.16 GAP91878.1 - 4.4e-17 61.7 0.0 1.1e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase UPF0086 PF01868.11 GAP91879.1 - 1.4e-24 85.5 0.0 1.9e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Fungal_trans_2 PF11951.3 GAP91880.1 - 2.3e-09 36.3 0.3 4.9e-09 35.2 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP91880.1 - 1e-06 28.5 13.1 1e-06 28.5 9.1 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2132 PF09905.4 GAP91880.1 - 0.13 12.1 0.3 9.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2132) WD40 PF00400.27 GAP91881.1 - 8.8e-23 79.3 1.5 0.00012 21.7 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat HAD_2 PF13419.1 GAP91882.1 - 1.2e-06 28.8 0.0 8.7e-05 22.8 0.0 2.2 1 1 1 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAP91882.1 - 0.00021 20.9 0.0 0.00039 20.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 GAP91882.1 - 0.03 14.7 0.0 0.04 14.3 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Metallophos_2 PF12850.2 GAP91883.1 - 2.3e-05 24.2 0.0 7.9e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 GAP91883.1 - 2.4e-05 23.8 0.3 7.1e-05 22.2 0.2 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF512 PF04459.7 GAP91883.1 - 0.13 11.2 0.0 0.3 10.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF512) DUF1664 PF07889.7 GAP91884.1 - 5.9e-16 58.4 33.2 8.1e-08 32.1 6.4 4.7 1 1 4 5 5 5 3 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.7 GAP91884.1 - 5.9e-12 45.4 23.9 7e-10 38.7 6.8 2.7 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.7 GAP91884.1 - 2e-10 40.6 25.2 2e-06 27.6 1.0 4.0 1 1 3 4 4 4 4 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 GAP91884.1 - 1.4e-08 34.5 22.0 9e-05 22.1 4.6 3.2 1 1 2 3 3 3 2 IncA protein Prefoldin_2 PF01920.15 GAP91884.1 - 3.3e-08 33.2 36.6 0.0074 16.0 0.6 5.5 2 1 2 5 5 5 4 Prefoldin subunit WEMBL PF05701.6 GAP91884.1 - 1.3e-07 30.4 28.4 0.00039 19.0 8.3 2.1 1 1 1 2 2 2 2 Weak chloroplast movement under blue light COG2 PF06148.6 GAP91884.1 - 1.5e-07 31.3 25.2 0.0095 15.8 3.8 4.7 1 1 3 4 4 4 3 COG (conserved oligomeric Golgi) complex component, COG2 ApoO PF09769.4 GAP91884.1 - 1.8e-07 31.0 5.5 0.012 15.3 0.5 3.6 1 1 2 3 3 3 2 Apolipoprotein O Filament PF00038.16 GAP91884.1 - 3.2e-07 30.1 19.6 0.00058 19.4 9.2 2.8 1 1 1 2 2 2 2 Intermediate filament protein Prominin PF05478.6 GAP91884.1 - 3.5e-07 28.1 23.8 2.5e-05 22.0 6.9 2.1 1 1 0 1 1 1 1 Prominin AAA_13 PF13166.1 GAP91884.1 - 4.2e-07 28.8 27.7 0.00026 19.6 10.2 2.0 1 1 1 2 2 2 2 AAA domain IFT57 PF10498.4 GAP91884.1 - 5.3e-07 28.7 27.6 0.00013 20.8 8.4 2.2 1 1 1 2 2 2 2 Intra-flagellar transport protein 57 Spc7 PF08317.6 GAP91884.1 - 6.6e-07 28.2 32.5 0.0015 17.2 9.0 2.2 1 1 1 2 2 2 2 Spc7 kinetochore protein TBPIP PF07106.8 GAP91884.1 - 1.2e-06 28.1 30.0 0.00093 18.7 5.3 4.3 1 1 3 4 4 4 3 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FH2 PF02181.18 GAP91884.1 - 2e-06 26.9 19.1 0.0024 16.8 5.5 2.3 1 1 1 2 2 2 2 Formin Homology 2 Domain Lebercilin PF15619.1 GAP91884.1 - 2.6e-06 27.0 20.7 0.014 14.7 4.2 3.5 1 1 1 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease ADIP PF11559.3 GAP91884.1 - 4.1e-06 26.7 24.8 0.0051 16.7 8.9 3.4 1 1 2 3 3 3 2 Afadin- and alpha -actinin-Binding Sec8_exocyst PF04048.9 GAP91884.1 - 1.6e-05 24.5 22.4 0.041 13.5 2.7 4.6 1 1 3 4 4 3 1 Sec8 exocyst complex component specific domain CCDC144C PF14915.1 GAP91884.1 - 1.8e-05 23.8 22.0 0.00022 20.2 6.0 2.4 1 1 1 2 2 2 2 CCDC144C protein coiled-coil region Leu_zip PF15294.1 GAP91884.1 - 2.4e-05 23.5 26.7 0.009 15.1 11.8 2.4 1 1 1 2 2 2 2 Leucine zipper DUF3606 PF12244.3 GAP91884.1 - 3.2e-05 23.4 4.0 0.15 11.7 0.0 4.1 3 1 1 4 4 4 1 Protein of unknown function (DUF3606) Laminin_II PF06009.7 GAP91884.1 - 4.8e-05 23.1 30.9 0.048 13.4 6.0 4.4 1 1 4 5 5 5 4 Laminin Domain II RmuC PF02646.11 GAP91884.1 - 5.5e-05 22.1 19.8 0.0078 15.0 1.2 3.8 1 1 3 4 4 4 3 RmuC family Bacillus_HBL PF05791.6 GAP91884.1 - 5.8e-05 22.5 28.0 0.0029 16.9 4.1 3.7 1 1 2 4 4 4 2 Bacillus haemolytic enterotoxin (HBL) Fib_alpha PF08702.5 GAP91884.1 - 7.4e-05 22.9 29.8 0.0007 19.7 2.9 3.7 1 1 2 3 3 3 1 Fibrinogen alpha/beta chain family DUF3584 PF12128.3 GAP91884.1 - 7.5e-05 20.2 17.9 7.5e-05 20.2 12.4 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF3584) ATG_C PF09333.6 GAP91884.1 - 7.7e-05 22.7 5.7 12 6.0 0.3 5.2 1 1 2 3 3 3 0 ATG C terminal domain EzrA PF06160.7 GAP91884.1 - 0.00012 20.3 21.3 0.021 13.0 1.4 2.3 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA DUF2959 PF11172.3 GAP91884.1 - 0.00013 21.8 14.3 0.016 15.0 8.3 2.5 1 1 0 2 2 2 1 Protein of unknown function (DUF2959) Tektin PF03148.9 GAP91884.1 - 0.00014 20.5 24.5 0.018 13.5 4.8 2.3 1 1 1 2 2 2 2 Tektin family DUF869 PF05911.6 GAP91884.1 - 0.00015 20.1 27.5 0.0012 17.1 13.0 2.0 1 1 1 2 2 2 2 Plant protein of unknown function (DUF869) FlxA PF14282.1 GAP91884.1 - 0.0002 21.2 34.1 0.066 13.1 1.0 4.7 1 1 4 5 5 5 3 FlxA-like protein DUF3375 PF11855.3 GAP91884.1 - 0.00022 20.1 12.1 0.014 14.1 0.9 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3375) Reo_sigmaC PF04582.7 GAP91884.1 - 0.00033 19.9 19.1 0.027 13.6 0.7 2.8 1 1 1 2 2 2 2 Reovirus sigma C capsid protein FliJ PF02050.11 GAP91884.1 - 0.00036 20.5 3.9 0.78 9.8 0.4 3.3 1 1 2 3 3 3 1 Flagellar FliJ protein DUF2746 PF10874.3 GAP91884.1 - 0.0004 20.4 17.2 0.52 10.5 2.0 6.1 1 1 3 4 4 4 1 Protein of unknown function (DUF2746) NPV_P10 PF05531.7 GAP91884.1 - 0.0005 20.2 37.2 0.29 11.3 3.7 5.2 1 1 4 5 5 5 3 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.2 GAP91884.1 - 0.00065 19.5 32.2 0.02 14.7 4.8 3.4 1 1 2 3 3 3 2 Tropomyosin like Sec34 PF04136.10 GAP91884.1 - 0.00076 19.2 12.3 0.44 10.2 0.1 4.4 2 1 2 4 4 3 1 Sec34-like family DNA_repr_REX1B PF14966.1 GAP91884.1 - 0.0011 19.2 13.5 6.1 7.2 0.2 5.2 1 1 4 5 5 5 0 DNA repair REX1-B Lectin_N PF03954.9 GAP91884.1 - 0.0011 18.3 22.9 0.0097 15.3 3.0 3.4 1 1 3 4 4 4 2 Hepatic lectin, N-terminal domain Mnd1 PF03962.10 GAP91884.1 - 0.0019 17.9 23.5 0.014 15.0 4.6 3.1 1 1 2 3 3 3 1 Mnd1 family DUF3384 PF11864.3 GAP91884.1 - 0.002 16.7 3.7 0.002 16.7 2.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Atg14 PF10186.4 GAP91884.1 - 0.0023 16.9 24.1 0.021 13.7 9.6 2.2 1 1 1 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 zf-C4H2 PF10146.4 GAP91884.1 - 0.0025 17.9 20.0 0.03 14.3 8.6 3.0 1 1 1 2 2 2 1 Zinc finger-containing protein THOC7 PF05615.8 GAP91884.1 - 0.0029 17.8 22.5 2.6 8.2 5.7 3.5 1 1 1 2 2 2 0 Tho complex subunit 7 AIP3 PF03915.8 GAP91884.1 - 0.0029 16.5 29.4 0.11 11.4 20.0 2.3 1 1 0 1 1 1 1 Actin interacting protein 3 CENP-F_leu_zip PF10473.4 GAP91884.1 - 0.003 17.4 26.1 12 5.7 17.7 3.2 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LXG PF04740.7 GAP91884.1 - 0.0031 17.3 23.7 0.064 13.0 7.8 3.0 1 1 1 2 2 2 1 LXG domain of WXG superfamily APG6 PF04111.7 GAP91884.1 - 0.0033 16.5 19.5 0.13 11.2 7.0 2.2 1 1 2 3 3 3 3 Autophagy protein Apg6 BicD PF09730.4 GAP91884.1 - 0.0034 15.8 25.4 0.019 13.3 4.7 2.0 1 1 1 2 2 2 1 Microtubule-associated protein Bicaudal-D DUF2458 PF10454.4 GAP91884.1 - 0.0035 17.2 18.4 0.26 11.1 4.3 3.5 1 1 2 3 3 3 1 Protein of unknown function (DUF2458) ATP-synt_B PF00430.13 GAP91884.1 - 0.0037 17.0 1.3 0.0037 17.0 0.9 3.9 1 1 3 4 4 4 1 ATP synthase B/B' CF(0) DUF4618 PF15397.1 GAP91884.1 - 0.0038 16.6 26.8 0.32 10.3 3.4 4.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4618) Syntaxin-6_N PF09177.6 GAP91884.1 - 0.0053 17.1 25.0 0.65 10.4 2.3 4.5 1 1 4 5 5 5 1 Syntaxin 6, N-terminal Gp58 PF07902.6 GAP91884.1 - 0.0056 14.9 21.6 0.0097 14.1 15.0 1.4 1 1 0 1 1 1 1 gp58-like protein MscS_porin PF12795.2 GAP91884.1 - 0.0057 16.0 1.4 0.0057 16.0 1.0 2.9 1 1 1 2 2 2 1 Mechanosensitive ion channel porin domain Baculo_p24 PF05073.7 GAP91884.1 - 0.0059 16.1 23.7 0.18 11.3 2.9 3.2 1 1 2 3 3 3 2 Baculovirus P24 capsid protein Tropomyosin PF00261.15 GAP91884.1 - 0.0075 15.3 25.3 0.17 10.9 3.5 3.3 1 1 2 3 3 3 2 Tropomyosin DUF1515 PF07439.6 GAP91884.1 - 0.0082 15.9 23.7 0.13 12.0 0.8 4.0 1 1 2 3 3 3 2 Protein of unknown function (DUF1515) Hemerythrin PF01814.18 GAP91884.1 - 0.0093 16.1 0.3 5.3 7.2 0.0 3.6 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain WXG100 PF06013.7 GAP91884.1 - 0.0097 15.8 9.0 6.9 6.7 0.3 5.6 2 1 5 7 7 6 0 Proteins of 100 residues with WXG Syntaxin PF00804.20 GAP91884.1 - 0.0098 16.0 32.3 0.71 10.0 6.6 4.3 1 1 3 4 4 4 1 Syntaxin Flu_NS2 PF00601.14 GAP91884.1 - 0.01 16.0 9.8 0.86 9.8 0.3 3.5 1 1 2 3 3 3 0 Influenza non-structural protein (NS2) DUF3708 PF12501.3 GAP91884.1 - 0.011 15.6 6.3 0.52 10.1 0.2 3.3 1 1 3 4 4 4 0 Phosphate ATP-binding cassette transporter DUF1110 PF06533.7 GAP91884.1 - 0.011 15.5 3.7 0.93 9.2 0.1 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF1110) MCPsignal PF00015.16 GAP91884.1 - 0.012 15.1 19.8 0.2 11.1 1.3 2.6 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain HlyE PF06109.8 GAP91884.1 - 0.013 14.5 22.1 0.019 13.9 1.4 3.8 1 1 3 4 4 4 0 Haemolysin E (HlyE) DUF148 PF02520.12 GAP91884.1 - 0.014 15.2 25.4 0.23 11.2 2.3 3.9 2 1 2 4 4 3 0 Domain of unknown function DUF148 DUF3322 PF11795.3 GAP91884.1 - 0.014 15.0 1.9 0.27 10.8 0.2 2.5 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) TMPIT PF07851.8 GAP91884.1 - 0.015 14.4 21.6 0.69 8.9 3.1 3.2 1 1 2 3 3 3 0 TMPIT-like protein DUF883 PF05957.8 GAP91884.1 - 0.017 15.4 15.7 2.1 8.7 0.5 4.1 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) MCC-bdg_PDZ PF10506.4 GAP91884.1 - 0.02 14.7 7.7 0.17 11.7 0.4 4.2 1 1 2 4 4 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome CTK3 PF12243.3 GAP91884.1 - 0.022 14.4 10.7 1.1 8.8 1.0 3.8 2 1 2 4 4 3 0 CTD kinase subunit gamma CTK3 Spectrin PF00435.16 GAP91884.1 - 0.025 14.8 18.4 0.93 9.8 2.7 3.7 1 1 2 3 3 3 0 Spectrin repeat Seryl_tRNA_N PF02403.17 GAP91884.1 - 0.03 14.3 31.0 0.46 10.5 6.3 4.1 1 1 4 5 5 5 0 Seryl-tRNA synthetase N-terminal domain Sipho_Gp157 PF05565.6 GAP91884.1 - 0.03 13.8 25.8 1.5 8.4 3.8 3.6 1 1 3 4 4 4 0 Siphovirus Gp157 YtxH PF12732.2 GAP91884.1 - 0.034 14.5 30.1 0.58 10.5 2.4 4.7 1 1 3 4 4 3 0 YtxH-like protein YjcZ PF13990.1 GAP91884.1 - 0.039 13.0 12.0 0.89 8.6 2.0 2.8 1 1 2 3 3 3 0 YjcZ-like protein GAS PF13851.1 GAP91884.1 - 0.041 13.0 24.4 0.092 11.9 11.0 2.5 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding PRD PF00874.15 GAP91884.1 - 0.048 13.7 1.9 2.4 8.3 0.1 3.4 2 1 0 3 3 3 0 PRD domain ERM PF00769.14 GAP91884.1 - 0.05 13.1 18.5 0.064 12.7 9.7 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family TTKRSYEDQ PF10212.4 GAP91884.1 - 0.053 12.4 11.9 0.46 9.3 1.0 2.7 1 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein YgaB PF14182.1 GAP91884.1 - 0.059 13.6 20.9 1.7 8.9 1.3 5.0 1 1 3 4 4 4 0 YgaB-like protein APG17 PF04108.7 GAP91884.1 - 0.063 12.0 23.4 1.1 7.9 10.5 3.0 1 1 1 2 2 2 0 Autophagy protein Apg17 Tweety PF04906.8 GAP91884.1 - 0.067 11.5 16.1 0.76 8.1 0.2 3.2 1 1 2 3 3 3 0 Tweety FliD_C PF07195.7 GAP91884.1 - 0.069 12.4 24.3 0.13 11.4 3.7 3.7 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 C-terminus DUF2935 PF11155.3 GAP91884.1 - 0.07 13.2 10.2 1.1 9.3 0.3 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF2935) Apc4 PF12896.2 GAP91884.1 - 0.075 12.3 4.2 2.1 7.6 0.2 3.7 1 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 4 DASH_Duo1 PF08651.5 GAP91884.1 - 0.077 12.5 15.2 5.1 6.7 0.4 5.6 1 1 4 5 5 5 0 DASH complex subunit Duo1 DUF745 PF05335.8 GAP91884.1 - 0.088 12.3 15.8 0.77 9.2 1.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF745) GTPase_Cys_C PF12631.2 GAP91884.1 - 0.094 13.1 1.8 32 5.0 0.5 3.7 1 1 2 3 3 3 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Herpes_U30 PF04523.8 GAP91884.1 - 0.1 10.0 7.4 0.64 7.4 0.1 2.9 1 1 2 3 3 3 0 Herpes virus tegument protein U30 PEP-utilisers_N PF05524.8 GAP91884.1 - 0.1 12.3 10.4 2.6 7.8 1.4 4.5 2 1 2 4 4 3 0 PEP-utilising enzyme, N-terminal Rootletin PF15035.1 GAP91884.1 - 0.11 12.4 14.0 20 5.0 9.7 3.0 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion OEP PF02321.13 GAP91884.1 - 0.12 11.8 7.3 3.3 7.2 0.3 2.9 1 1 2 3 3 3 0 Outer membrane efflux protein DASH_Dad2 PF08654.5 GAP91884.1 - 0.13 12.2 17.3 1.7 8.6 0.3 5.2 1 1 4 5 5 5 0 DASH complex subunit Dad2 CorA PF01544.13 GAP91884.1 - 0.13 11.2 15.2 0.53 9.2 0.4 3.1 1 1 2 3 3 3 0 CorA-like Mg2+ transporter protein DUF948 PF06103.6 GAP91884.1 - 0.14 12.0 32.3 2.3 8.1 5.1 4.8 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) BEX PF04538.7 GAP91884.1 - 0.15 12.2 7.8 1.2 9.4 0.2 3.4 1 1 1 2 2 2 0 Brain expressed X-linked like family DUF972 PF06156.8 GAP91884.1 - 0.15 12.3 20.9 1e+02 3.3 2.0 4.1 1 1 1 2 2 1 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 GAP91884.1 - 0.15 9.8 23.8 1.1 7.0 6.1 2.6 1 1 2 3 3 3 0 V-type ATPase 116kDa subunit family Flagellar_rod PF05149.7 GAP91884.1 - 0.16 11.1 20.7 0.4 9.8 2.2 3.8 1 1 1 2 2 2 0 Paraflagellar rod protein GrpE PF01025.14 GAP91884.1 - 0.17 11.4 22.2 0.12 11.9 4.7 3.1 1 1 2 3 3 3 0 GrpE Phage_GP20 PF06810.6 GAP91884.1 - 0.18 11.2 37.2 2.6 7.4 6.3 3.6 1 1 2 3 3 3 0 Phage minor structural protein GP20 PLA2G12 PF06951.6 GAP91884.1 - 0.19 11.3 6.7 50 3.4 2.5 3.8 1 1 1 2 2 2 0 Group XII secretory phospholipase A2 precursor (PLA2G12) DUF4407 PF14362.1 GAP91884.1 - 0.19 10.6 17.4 3.2 6.6 12.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Mod_r PF07200.8 GAP91884.1 - 0.23 11.3 21.1 1.8 8.4 4.4 3.4 1 1 3 4 4 4 0 Modifier of rudimentary (Mod(r)) protein DUF2968 PF11180.3 GAP91884.1 - 0.23 10.8 12.9 0.16 11.3 0.7 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) HOOK PF05622.7 GAP91884.1 - 0.23 9.1 22.1 0.37 8.5 15.3 1.4 1 0 0 1 1 1 0 HOOK protein DUF812 PF05667.6 GAP91884.1 - 0.26 9.7 26.7 3.2 6.1 18.6 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF2390 PF09523.5 GAP91884.1 - 0.26 11.4 4.1 4.4 7.5 0.3 3.0 1 1 3 4 4 4 0 Protein of unknown function (DUF2390) ASL_C PF08328.6 GAP91884.1 - 0.27 11.1 12.1 0.47 10.3 0.2 3.7 1 1 2 3 3 3 0 Adenylosuccinate lyase C-terminal Nup88 PF10168.4 GAP91884.1 - 0.35 8.6 19.1 1.5 6.5 13.2 1.9 1 1 0 1 1 1 0 Nuclear pore component Transposase_22 PF02994.9 GAP91884.1 - 0.36 9.2 28.0 0.46 8.9 7.7 2.2 1 1 1 2 2 2 0 L1 transposable element CCDC-167 PF15188.1 GAP91884.1 - 0.36 10.7 18.7 2.4 8.1 2.0 4.1 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 DUF2408 PF10303.4 GAP91884.1 - 0.39 10.8 25.0 0.27 11.3 10.1 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2408) UPF0449 PF15136.1 GAP91884.1 - 0.42 10.8 21.0 2 8.6 0.6 5.3 1 1 4 5 5 5 0 Uncharacterised protein family UPF0449 DUF651 PF04895.7 GAP91884.1 - 0.42 10.2 11.4 9.1 5.9 0.7 4.4 1 1 4 5 5 4 0 Archaeal protein of unknown function (DUF651) LMP PF04778.7 GAP91884.1 - 0.45 10.2 34.2 0.35 10.6 4.5 3.3 1 1 1 2 2 2 0 LMP repeated region EMP24_GP25L PF01105.19 GAP91884.1 - 0.54 9.9 23.1 5.8 6.5 2.3 4.5 1 1 2 3 3 3 0 emp24/gp25L/p24 family/GOLD Lysozyme_like PF13702.1 GAP91884.1 - 0.59 9.6 12.9 9.9 5.6 0.1 4.0 1 1 3 4 4 4 0 Lysozyme-like IDEAL PF08858.5 GAP91884.1 - 0.61 9.6 11.3 25 4.4 0.1 5.1 5 0 0 5 5 5 0 IDEAL domain DUF4200 PF13863.1 GAP91884.1 - 0.64 9.9 16.4 5 7.0 3.5 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Adeno_PIX PF03955.9 GAP91884.1 - 0.7 10.4 10.5 13 6.3 0.6 4.3 1 1 3 4 4 3 0 Adenovirus hexon-associated protein (IX) DUF1484 PF07363.6 GAP91884.1 - 0.72 10.2 6.3 4.8 7.5 1.0 3.4 1 1 3 4 4 3 0 Protein of unknown function (DUF1484) DUF3508 PF12018.3 GAP91884.1 - 0.73 8.7 9.0 0.33 9.9 0.7 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF3508) Allexi_40kDa PF05549.6 GAP91884.1 - 0.78 8.9 21.8 1.4 8.1 1.2 3.1 1 1 2 3 3 3 0 Allexivirus 40kDa protein DUF1845 PF08900.6 GAP91884.1 - 0.87 8.8 10.6 13 5.0 0.1 4.2 2 1 1 4 4 4 0 Domain of unknown function (DUF1845) Cep57_MT_bd PF06657.8 GAP91884.1 - 0.89 9.5 19.4 0.56 10.1 1.6 4.0 2 1 1 4 4 2 0 Centrosome microtubule-binding domain of Cep57 Vps53_N PF04100.7 GAP91884.1 - 1 8.0 27.0 2.4 6.8 6.9 3.1 1 1 2 3 3 3 0 Vps53-like, N-terminal YojJ PF10372.4 GAP91884.1 - 1 9.2 7.2 21 5.0 0.1 4.4 2 1 2 5 5 5 0 Bacterial membrane-spanning protein N-terminus Cytochrom_B562 PF07361.6 GAP91884.1 - 1.2 9.6 20.1 4.9 7.6 2.5 3.7 1 1 1 2 2 2 0 Cytochrome b562 Jnk-SapK_ap_N PF09744.4 GAP91884.1 - 1.2 9.1 23.4 9.2 6.2 3.8 3.4 1 1 3 4 4 4 0 JNK_SAPK-associated protein-1 DUF3552 PF12072.3 GAP91884.1 - 1.2 8.2 25.0 1.7 7.7 6.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF4164 PF13747.1 GAP91884.1 - 1.2 9.2 19.9 3.6 7.7 3.2 4.2 1 1 1 3 3 3 0 Domain of unknown function (DUF4164) Fzo_mitofusin PF04799.8 GAP91884.1 - 1.4 8.3 22.5 19 4.5 0.1 4.3 1 1 5 6 6 6 0 fzo-like conserved region LOH1CR12 PF10158.4 GAP91884.1 - 1.6 8.5 14.2 3.7 7.3 0.4 4.1 1 1 3 4 4 4 0 Tumour suppressor protein Effector_1 PF04518.7 GAP91884.1 - 1.6 7.6 14.9 2.4 7.0 2.2 2.4 1 1 1 2 2 2 0 Effector from type III secretion system Cauli_AT PF03233.8 GAP91884.1 - 1.7 8.3 33.3 4.2 7.0 2.1 4.5 1 1 4 5 5 5 0 Aphid transmission protein YscO PF07321.7 GAP91884.1 - 1.9 8.3 16.5 2.2 8.0 0.6 3.3 1 1 2 3 3 3 0 Type III secretion protein YscO TMP_2 PF06791.8 GAP91884.1 - 1.9 8.0 12.5 0.91 9.1 2.3 3.0 1 1 2 3 3 3 0 Prophage tail length tape measure protein DUF489 PF04356.7 GAP91884.1 - 2.2 7.8 7.8 11 5.6 1.6 2.9 1 1 2 3 3 2 0 Protein of unknown function (DUF489) Striatin PF08232.7 GAP91884.1 - 2.4 8.4 21.3 21 5.4 5.8 2.9 1 1 1 2 2 2 0 Striatin family DegS PF05384.6 GAP91884.1 - 2.4 7.3 20.5 8.4 5.5 1.2 4.1 1 1 2 3 3 3 0 Sensor protein DegS DUF3450 PF11932.3 GAP91884.1 - 2.4 7.3 16.5 1.1 8.4 2.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FlaC_arch PF05377.6 GAP91884.1 - 3 7.8 31.9 3 7.8 0.7 7.0 1 1 3 4 4 3 0 Flagella accessory protein C (FlaC) CCD PF07860.6 GAP91884.1 - 3.3 7.1 9.2 36 3.8 0.3 4.0 1 1 2 4 4 4 0 WisP family C-Terminal Region GLE1 PF07817.8 GAP91884.1 - 3.3 6.5 20.4 1.3 7.9 2.7 3.2 1 1 2 3 3 3 0 GLE1-like protein Tup_N PF08581.5 GAP91884.1 - 3.4 7.9 14.2 3.9 7.7 1.3 3.8 1 1 3 5 5 3 0 Tup N-terminal FimP PF09766.4 GAP91884.1 - 3.4 6.6 23.9 0.5 9.3 2.0 4.0 1 1 2 3 3 3 0 Fms-interacting protein DUF2203 PF09969.4 GAP91884.1 - 4 7.6 17.3 1.4e+02 2.6 0.2 3.9 1 1 1 2 2 1 0 Uncharacterized conserved protein (DUF2203) DUF4446 PF14584.1 GAP91884.1 - 4.7 7.0 18.4 6.4 6.5 0.9 4.0 1 1 4 5 5 5 0 Protein of unknown function (DUF4446) COG7 PF10191.4 GAP91884.1 - 4.7 4.9 18.7 14 3.4 4.5 2.9 1 1 2 3 3 3 0 Golgi complex component 7 (COG7) Cluap1 PF10234.4 GAP91884.1 - 5.6 6.0 30.3 4.6 6.3 1.1 3.4 1 1 2 3 3 3 0 Clusterin-associated protein-1 HAUS-augmin3 PF14932.1 GAP91884.1 - 5.7 6.0 19.0 8.5 5.4 4.0 2.7 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 COG5 PF10392.4 GAP91884.1 - 6.7 6.6 22.5 7.6 6.4 4.2 3.3 1 1 2 3 3 3 0 Golgi transport complex subunit 5 DUF1451 PF07295.6 GAP91884.1 - 7 6.4 21.0 4.9 6.9 2.0 3.9 1 1 2 3 3 2 0 Protein of unknown function (DUF1451) End3 PF12761.2 GAP91884.1 - 7 6.2 27.0 18 4.8 1.1 3.6 1 1 2 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 DUF3810 PF12725.2 GAP91884.1 - 7.3 5.3 12.4 2.2 7.0 1.2 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF3810) Peptidase_C6 PF00851.13 GAP91884.1 - 7.5 5.0 11.3 4.4 5.8 4.0 2.1 1 1 1 2 2 2 0 Helper component proteinase KxDL PF10241.4 GAP91884.1 - 7.7 6.4 17.1 23 4.9 1.5 4.9 1 1 2 3 3 2 0 Uncharacterized conserved protein Tho2 PF11262.3 GAP91884.1 - 8.1 5.3 18.5 18 4.2 4.9 3.3 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF349 PF03993.7 GAP91884.1 - 8.4 6.6 13.4 18 5.5 0.5 3.7 1 1 3 4 4 4 0 Domain of Unknown Function (DUF349) Prefoldin PF02996.12 GAP91884.1 - 8.7 6.0 28.7 8 6.1 0.7 6.0 1 1 3 4 4 4 0 Prefoldin subunit Filo_VP35 PF02097.10 GAP91884.1 - 8.7 5.4 19.0 2.8 7.0 1.9 3.0 1 1 2 3 3 3 0 Filoviridae VP35 Phage_GPO PF05929.6 GAP91884.1 - 10 5.3 21.9 14 4.8 4.3 3.1 1 1 3 4 4 4 0 Phage capsid scaffolding protein (GPO) serine peptidase TPR_11 PF13414.1 GAP91885.1 - 7.3e-11 41.5 5.2 7.3e-11 41.5 3.6 2.2 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 GAP91885.1 - 0.0001 22.1 2.8 0.0001 22.1 2.0 2.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAP91885.1 - 0.00034 20.2 6.2 0.23 11.4 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAP91885.1 - 0.00096 18.6 7.5 0.014 14.9 0.1 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAP91885.1 - 0.0024 18.1 1.2 0.0024 18.1 0.8 2.3 2 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 GAP91885.1 - 0.0078 16.3 2.3 0.0078 16.3 1.6 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 GAP91885.1 - 0.016 14.9 2.5 4 7.4 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat FIVAR PF07554.8 GAP91885.1 - 0.11 12.8 1.3 0.83 9.9 0.0 2.6 2 1 1 3 3 3 0 Uncharacterised Sugar-binding Domain DUF2560 PF10834.3 GAP91885.1 - 0.16 11.9 1.6 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2560) Amidase PF01425.16 GAP91886.1 - 3.8e-80 269.9 0.0 1.6e-78 264.5 0.0 2.8 1 1 0 1 1 1 1 Amidase CDC27 PF09507.5 GAP91887.1 - 4.7e-87 292.9 21.2 6.2e-87 292.5 14.7 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 DUF2151 PF10221.4 GAP91887.1 - 0.91 7.6 7.3 1.3 7.1 5.0 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator PBP_sp32 PF07222.7 GAP91887.1 - 2.5 7.1 7.7 6.1 5.9 5.3 1.6 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Nop14 PF04147.7 GAP91887.1 - 2.9 5.6 14.9 4.2 5.1 10.3 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 GAP91887.1 - 6.4 4.6 12.4 11 3.9 8.6 1.2 1 0 0 1 1 1 0 CDC45-like protein AvrE PF11725.3 GAP91887.1 - 7.5 3.4 13.6 10 2.9 9.4 1.1 1 0 0 1 1 1 0 Pathogenicity factor Na_trans_assoc PF06512.8 GAP91887.1 - 8.8 6.2 11.8 16 5.3 6.7 2.2 2 0 0 2 2 2 0 Sodium ion transport-associated zf-C3HC4 PF00097.20 GAP91888.1 - 2e-09 36.9 14.7 2.8e-09 36.4 6.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAP91888.1 - 3.2e-08 33.4 14.7 6.8e-08 32.4 6.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAP91888.1 - 5.2e-08 32.5 12.6 3.2e-07 30.0 6.3 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 GAP91888.1 - 7.3e-08 32.0 13.0 9.8e-08 31.6 6.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 GAP91888.1 - 1.6e-07 30.8 12.7 4.6e-07 29.3 5.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.22 GAP91888.1 - 5.5e-06 25.7 0.0 1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 SAP domain zf-C3HC4_4 PF15227.1 GAP91888.1 - 3.1e-05 23.7 9.4 3.1e-05 23.7 6.5 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 GAP91888.1 - 3.3e-05 23.5 2.4 3.3e-05 23.5 1.6 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 GAP91888.1 - 7.8e-05 22.7 5.1 0.00046 20.2 2.1 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 GAP91888.1 - 9.2e-05 22.0 6.6 9.2e-05 22.0 4.6 2.9 3 0 0 3 3 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 GAP91888.1 - 0.0026 17.3 2.9 0.0026 17.3 2.0 2.9 2 1 1 3 3 3 1 RING/Ubox like zinc-binding domain Mob_synth_C PF06463.8 GAP91888.1 - 0.012 15.2 3.4 0.028 14.0 2.3 1.6 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C zf-Apc11 PF12861.2 GAP91888.1 - 0.035 13.9 0.9 0.035 13.9 0.6 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.9 GAP91888.1 - 0.063 12.7 3.8 5.1 6.6 0.1 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif Pex14_N PF04695.8 GAP91888.1 - 8.1 6.4 8.2 1.1 9.3 0.5 2.5 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Snf7 PF03357.16 GAP91889.1 - 1.4e-15 57.0 7.7 2.1e-15 56.5 5.3 1.3 1 0 0 1 1 1 1 Snf7 PVL_ORF50 PF07768.6 GAP91889.1 - 0.64 10.0 2.9 0.66 9.9 0.4 2.0 2 0 0 2 2 2 0 PVL ORF-50-like family Atg14 PF10186.4 GAP91889.1 - 2.9 6.7 6.3 0.34 9.8 1.2 1.6 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 PPR_2 PF13041.1 GAP91892.1 - 8.5e-49 163.3 3.1 2.2e-09 37.1 0.0 13.7 10 3 5 15 15 15 11 PPR repeat family PPR PF01535.15 GAP91892.1 - 6.5e-25 85.3 26.7 0.00029 20.5 0.0 13.6 18 0 0 18 18 18 5 PPR repeat PPR_1 PF12854.2 GAP91892.1 - 2.4e-23 81.3 4.4 1.8e-08 33.6 0.0 9.9 11 0 0 11 11 11 6 PPR repeat PPR_3 PF13812.1 GAP91892.1 - 5.5e-23 79.2 23.4 0.004 17.3 0.0 13.6 16 0 0 16 16 16 7 Pentatricopeptide repeat domain RPM2 PF08579.6 GAP91892.1 - 0.00021 21.3 0.1 0.036 14.2 0.0 3.8 4 1 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.2 GAP91892.1 - 0.015 14.6 0.0 0.1 11.9 0.0 2.4 2 1 0 2 2 2 0 Mitochondrial ATPase expression TPR_14 PF13428.1 GAP91892.1 - 0.056 14.1 8.2 24 5.9 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat DEAD PF00270.24 GAP91893.1 - 3.6e-43 146.9 0.1 5.3e-43 146.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP91893.1 - 5.2e-20 71.0 0.0 1.2e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 GAP91893.1 - 4.2e-15 55.0 0.1 8.7e-15 54.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 GAP91893.1 - 0.013 15.2 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TRAPPC-Trs85 PF12739.2 GAP91894.1 - 1e-110 370.2 0.0 1.5e-110 369.7 0.0 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Acetyltransf_1 PF00583.19 GAP91895.1 - 2.3e-06 27.5 0.0 4.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAP91895.1 - 8.8e-06 25.7 0.0 1.4e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAP91895.1 - 0.0022 17.8 0.1 0.0041 16.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAP91895.1 - 0.0041 17.2 0.0 0.01 15.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF1510 PF07423.6 GAP91896.1 - 0.074 12.4 34.3 0.12 11.7 23.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SAPS PF04499.10 GAP91896.1 - 0.25 9.9 10.3 0.39 9.3 7.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Merozoite_SPAM PF07133.6 GAP91896.1 - 0.54 10.1 41.7 1 9.2 28.9 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF2413 PF10310.4 GAP91896.1 - 0.55 8.9 23.8 0.85 8.3 16.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) CT47 PF15623.1 GAP91896.1 - 1.5 8.4 35.4 2.3 7.8 24.5 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 Zip PF02535.17 GAP91896.1 - 1.6 7.6 8.8 2.5 7.0 6.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.7 GAP91896.1 - 1.7 6.4 35.4 2.6 5.8 24.5 1.1 1 0 0 1 1 1 0 Nop14-like family Ycf1 PF05758.7 GAP91896.1 - 1.8 6.1 23.0 2.5 5.7 15.9 1.1 1 0 0 1 1 1 0 Ycf1 MIP-T3 PF10243.4 GAP91896.1 - 2.1 6.7 47.5 3 6.2 32.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 zf-C2H2_4 PF13894.1 GAP91896.1 - 2.7 8.5 27.4 0.59 10.5 0.8 5.4 5 0 0 5 5 4 0 C2H2-type zinc finger CENP-T PF15511.1 GAP91896.1 - 3 6.9 25.1 4.2 6.5 0.1 2.5 3 0 0 3 3 3 0 Centromere kinetochore component CENP-T RR_TM4-6 PF06459.7 GAP91896.1 - 3.7 7.3 32.0 7 6.4 22.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 zf-C2H2 PF00096.21 GAP91896.1 - 3.8 8.0 16.1 1.2 9.6 0.4 3.5 3 0 0 3 3 2 0 Zinc finger, C2H2 type SprA-related PF12118.3 GAP91896.1 - 4.2 6.5 22.9 7.5 5.7 15.9 1.3 1 0 0 1 1 1 0 SprA-related family Vfa1 PF08432.5 GAP91896.1 - 5.3 7.0 34.9 9.8 6.1 24.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC27 PF09507.5 GAP91896.1 - 6.8 5.7 37.9 9.3 5.3 26.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2201_N PF13203.1 GAP91896.1 - 10 5.2 16.0 16 4.5 11.1 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Secretin_N_2 PF07655.8 GAP91898.1 - 0.18 12.2 12.0 0.32 11.4 8.3 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain GCD14 PF08704.5 GAP91898.1 - 0.21 11.0 0.0 2 7.8 0.0 2.1 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Transferase PF02458.10 GAP91899.1 - 1.2e-41 142.5 0.0 2.7e-17 62.3 0.0 3.0 3 0 0 3 3 3 3 Transferase family FAD_binding_4 PF01565.18 GAP91900.1 - 3e-17 62.4 0.0 4.8e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP91900.1 - 0.024 14.5 0.7 0.15 11.9 0.1 2.5 2 0 0 2 2 2 0 Berberine and berberine like PAT1 PF09770.4 GAP91901.1 - 7.7 4.6 16.8 9.5 4.3 11.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S9 PF00326.16 GAP91902.1 - 9.6e-06 24.9 0.2 0.023 13.9 0.0 2.7 3 0 0 3 3 3 2 Prolyl oligopeptidase family Esterase PF00756.15 GAP91902.1 - 1.4e-05 24.6 0.0 9.3e-05 21.9 0.0 2.2 1 1 0 1 1 1 1 Putative esterase FAD_binding_2 PF00890.19 GAP91903.1 - 1.2e-56 192.4 11.2 1.4e-56 192.1 7.8 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAP91903.1 - 6.1e-07 29.3 1.1 2.7e-06 27.2 0.7 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAP91903.1 - 9.6e-06 25.7 0.3 1.6e-05 25.0 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAP91903.1 - 9.3e-05 21.4 4.8 0.0006 18.8 3.3 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 GAP91903.1 - 0.0073 15.4 4.2 0.018 14.1 2.9 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAP91903.1 - 0.04 12.9 0.2 0.21 10.6 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.9 GAP91903.1 - 0.05 13.4 0.1 0.15 11.9 0.1 1.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAP91903.1 - 0.71 8.6 8.4 0.18 10.6 1.4 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A PGM_PMM_I PF02878.11 GAP91904.1 - 1.1e-33 115.6 0.0 1.6e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 GAP91904.1 - 6.2e-25 87.4 0.0 1.1e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 GAP91904.1 - 3.7e-15 56.1 0.0 7.6e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 GAP91904.1 - 9e-08 32.0 0.0 2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RNase_T PF00929.19 GAP91905.1 - 2e-25 89.9 0.1 2.3e-25 89.7 0.0 1.0 1 0 0 1 1 1 1 Exonuclease APH PF01636.18 GAP91906.1 - 3.7e-19 69.4 3.8 3.7e-19 69.4 2.6 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAP91906.1 - 0.00024 20.7 0.0 0.00042 19.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 GAP91906.1 - 0.013 14.8 0.0 3.9 6.7 0.0 2.6 1 1 1 2 2 2 0 RIO1 family HTH_Tnp_Tc5 PF03221.11 GAP91906.1 - 0.082 12.7 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain Pkinase_Tyr PF07714.12 GAP91906.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase AA_permease_2 PF13520.1 GAP91907.1 - 5e-59 199.9 17.3 6.7e-59 199.5 12.0 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAP91907.1 - 1.8e-21 76.0 21.9 1.8e-21 76.0 15.2 2.3 2 1 0 2 2 2 2 Amino acid permease SOG2 PF10428.4 GAP91908.1 - 0.079 11.6 0.1 0.096 11.3 0.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein LXG PF04740.7 GAP91908.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily TALPID3 PF15324.1 GAP91908.1 - 0.23 8.7 4.9 0.29 8.4 3.4 1.1 1 0 0 1 1 1 0 Hedgehog signalling target VSP PF03302.8 GAP91909.1 - 0.0023 16.6 2.2 0.0047 15.6 1.5 1.4 1 0 0 1 1 1 1 Giardia variant-specific surface protein SKG6 PF08693.5 GAP91909.1 - 1.3 8.4 5.1 0.98 8.7 0.2 2.6 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Xpo1 PF08389.7 GAP91910.1 - 7e-28 97.4 3.4 1.3e-27 96.5 0.8 2.8 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 GAP91910.1 - 1.6e-05 24.6 0.1 0.0004 20.2 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 GAP91910.1 - 0.0066 14.8 2.0 0.21 9.8 0.2 2.6 2 0 0 2 2 2 2 Adaptin N terminal region 5-FTHF_cyc-lig PF01812.15 GAP91911.1 - 1.3e-28 100.0 0.0 2e-28 99.4 0.0 1.3 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family OPT PF03169.10 GAP91913.1 - 5e-208 692.4 34.8 5.9e-208 692.2 24.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MFS_1 PF07690.11 GAP91914.1 - 0.022 13.4 0.3 0.033 12.9 0.2 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily GTP_EFTU PF00009.22 GAP91916.1 - 4.3e-63 212.1 0.3 6.2e-63 211.6 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 GAP91916.1 - 3.3e-37 126.7 0.0 8.9e-37 125.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 GAP91916.1 - 6.4e-22 77.2 0.0 1.9e-21 75.7 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 GAP91916.1 - 1.9e-13 50.3 0.1 1.9e-13 50.3 0.1 2.9 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_II PF14492.1 GAP91916.1 - 4.5e-12 45.6 0.0 1.3e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 GAP91916.1 - 2.5e-05 24.1 0.2 6.5e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase PAD_M PF08527.5 GAP91916.1 - 0.091 12.1 0.1 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain Solute_trans_a PF03619.11 GAP91918.1 - 4e-106 354.3 9.3 4.9e-106 354.0 6.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Glyco_hydro_92 PF07971.7 GAP91919.1 - 2.4e-155 518.0 0.0 3.1e-155 517.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Isochorismatase PF00857.15 GAP91920.1 - 1.6e-18 67.2 0.1 2.3e-18 66.7 0.1 1.2 1 0 0 1 1 1 1 Isochorismatase family zf-BED PF02892.10 GAP91921.1 - 0.0059 16.3 1.8 0.0059 16.3 1.3 2.4 2 0 0 2 2 2 1 BED zinc finger Zn_clus PF00172.13 GAP91921.1 - 0.023 14.6 6.5 0.057 13.3 4.5 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Iso_dh PF00180.15 GAP91922.1 - 1.6e-99 333.1 0.0 2e-99 332.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Sec5 PF15469.1 GAP91923.1 - 1.4e-36 125.9 0.0 2.3e-35 121.9 0.0 2.7 2 1 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 GAP91923.1 - 0.00014 21.6 0.7 0.00062 19.5 0.1 2.5 2 0 0 2 2 2 1 Vps51/Vps67 Oxysterol_BP PF01237.13 GAP91925.1 - 3.3e-90 302.1 0.0 4e-90 301.8 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein DUF2956 PF11169.3 GAP91925.1 - 0.84 9.6 5.0 0.14 12.0 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Fringe PF02434.11 GAP91926.1 - 1.4e-05 24.4 0.0 2.3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Fringe-like PAN_1 PF00024.21 GAP91926.1 - 0.00064 19.4 0.1 0.0011 18.6 0.1 1.3 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 GAP91926.1 - 0.013 15.1 1.3 0.027 14.1 0.9 1.4 1 0 0 1 1 1 0 PAN domain CFEM PF05730.6 GAP91927.1 - 5.8e-15 54.8 10.4 9.6e-15 54.1 7.2 1.4 1 0 0 1 1 1 1 CFEM domain Asn_synthase PF00733.16 GAP91928.1 - 8.7e-56 189.2 0.0 1.2e-55 188.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 GAP91928.1 - 1e-08 34.9 0.0 1.3e-07 31.3 0.0 2.8 4 1 0 4 4 4 1 Glutamine amidotransferase domain GATase_6 PF13522.1 GAP91928.1 - 0.00023 21.1 0.0 0.013 15.4 0.0 2.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 GAP91928.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Aluminium induced protein AMP-binding PF00501.23 GAP91929.1 - 2.5e-63 213.9 0.0 3.2e-63 213.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAP91929.1 - 3e-11 44.0 0.0 9.6e-11 42.4 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Hydrolase PF00702.21 GAP91929.1 - 0.038 14.3 0.2 0.22 11.8 0.1 2.4 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Sulfate_transp PF00916.15 GAP91930.1 - 1.3e-49 168.6 4.9 2.1e-49 168.0 3.4 1.3 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 GAP91930.1 - 1.9e-28 97.9 2.6 1.9e-28 97.9 1.8 3.3 3 1 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 GAP91930.1 - 4.3e-10 39.0 0.0 8.1e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 STAS domain YiiD_Cterm PF09500.5 GAP91930.1 - 0.002 17.6 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Putative thioesterase (yiiD_Cterm) STAS_2 PF13466.1 GAP91930.1 - 0.0097 15.9 0.8 0.031 14.3 0.6 1.9 1 0 0 1 1 1 1 STAS domain B12D PF06522.6 GAP91930.1 - 0.34 10.6 1.5 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Cupin_1 PF00190.17 GAP91931.1 - 1.3e-31 108.9 0.0 8.8e-17 60.8 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 GAP91931.1 - 6.2e-30 102.5 0.9 2.5e-15 55.7 0.3 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 GAP91931.1 - 2e-08 34.0 0.2 0.0008 19.1 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.7 GAP91931.1 - 6.6e-08 31.8 0.0 0.00078 18.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.13 GAP91931.1 - 0.0014 18.2 0.0 0.15 11.6 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase 3-HAO PF06052.7 GAP91931.1 - 0.018 14.4 0.0 0.085 12.2 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase ARD PF03079.9 GAP91931.1 - 0.019 14.9 0.8 0.95 9.3 0.0 2.3 2 0 0 2 2 2 0 ARD/ARD' family Cupin_7 PF12973.2 GAP91931.1 - 0.032 14.0 0.1 0.26 11.1 0.0 2.5 2 1 0 2 2 2 0 ChrR Cupin-like domain GPI PF06560.6 GAP91931.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) 2OG-FeII_Oxy_5 PF13759.1 GAP91931.1 - 0.11 12.7 0.1 7.9 6.8 0.0 3.1 2 1 1 3 3 3 0 Putative 2OG-Fe(II) oxygenase FIBP PF05427.6 GAP91931.1 - 0.12 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Acidic fibroblast growth factor binding (FIBP) DUF1275 PF06912.6 GAP91932.1 - 2.4e-39 134.7 15.2 3.1e-39 134.3 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) MFS_1 PF07690.11 GAP91933.1 - 4.2e-45 153.9 51.7 2.3e-44 151.5 34.6 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Tmemb_18A PF09771.4 GAP91933.1 - 0.017 15.1 0.3 0.083 12.8 0.5 1.9 2 0 0 2 2 2 0 Transmembrane protein 188 Sex_peptide PF08138.6 GAP91933.1 - 0.017 14.9 0.1 0.061 13.1 0.1 2.0 1 1 0 1 1 1 0 Sex peptide (SP) family DUF4623 PF15416.1 GAP91934.1 - 0.079 11.3 0.0 0.1 10.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4623) FAD_binding_3 PF01494.14 GAP91936.1 - 1.3e-16 60.6 0.2 2e-10 40.2 0.1 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAP91936.1 - 8.6e-05 22.4 0.0 0.00019 21.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAP91936.1 - 0.011 15.8 0.0 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAP91936.1 - 0.011 16.0 0.1 0.27 11.6 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAP91936.1 - 0.11 11.2 0.0 0.22 10.3 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain Epimerase PF01370.16 GAP91937.1 - 1.5e-20 73.6 0.0 1.9e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAP91937.1 - 2.8e-09 37.0 0.2 4.8e-09 36.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 GAP91937.1 - 1.4e-08 34.0 0.0 2e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 GAP91937.1 - 4.9e-08 32.0 0.0 6.3e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAP91937.1 - 1.6e-07 31.5 0.0 2.5e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAP91937.1 - 3.7e-06 26.0 0.0 0.00011 21.2 0.0 2.2 1 1 1 2 2 2 1 Male sterility protein KR PF08659.5 GAP91937.1 - 0.0055 16.3 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 KR domain SGL PF08450.7 GAP91938.1 - 6.2e-22 78.1 0.2 1.4e-21 77.0 0.1 1.7 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 GAP91938.1 - 0.00043 20.2 0.0 0.0014 18.6 0.0 1.8 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.15 GAP91938.1 - 0.00074 19.4 0.1 0.016 15.1 0.0 3.0 3 1 1 4 4 4 1 Arylesterase NHL PF01436.16 GAP91938.1 - 0.0053 16.6 0.4 0.8 9.7 0.0 3.5 3 0 0 3 3 3 1 NHL repeat Mucin PF01456.12 GAP91939.1 - 0.012 15.3 20.3 0.014 15.1 14.1 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Rubella_E2 PF05749.6 GAP91939.1 - 0.26 10.4 11.0 0.32 10.2 7.6 1.1 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 SSP160 PF06933.6 GAP91939.1 - 0.63 7.9 19.7 0.65 7.8 13.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 E1-E2_ATPase PF00122.15 GAP91940.1 - 9.8e-19 67.3 0.0 1.9e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 GAP91940.1 - 2.6e-15 57.4 0.2 4.3e-12 46.9 0.1 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAP91940.1 - 1.7e-11 44.6 0.0 1.3e-10 41.7 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAP91940.1 - 4.4e-11 42.5 0.0 1.4e-10 40.9 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAP91940.1 - 0.0021 17.6 0.0 0.0055 16.3 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Fe-ADH PF00465.14 GAP91940.1 - 0.07 11.7 0.3 0.13 10.8 0.0 1.5 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase VPS9 PF02204.13 GAP91941.1 - 6.1e-31 106.5 0.0 1e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 GAP91941.1 - 1.7e-09 36.9 0.1 3e-08 32.9 0.0 2.6 2 0 0 2 2 2 1 CUE domain DUF605 PF04652.11 GAP91941.1 - 0.0031 16.9 1.7 0.0031 16.9 1.2 3.3 2 1 1 3 3 3 1 Vta1 like DHquinase_I PF01487.10 GAP91943.1 - 1.6e-29 103.2 0.0 2.4e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 GAP91943.1 - 2.6e-17 62.6 0.1 1.1e-16 60.6 0.0 2.1 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 GAP91943.1 - 1.2e-15 57.6 0.0 2.4e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.15 GAP91943.1 - 2.5e-14 53.5 0.1 6.9e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.1 GAP91943.1 - 0.0091 15.8 0.6 0.12 12.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain F420_oxidored PF03807.12 GAP91943.1 - 0.011 16.0 0.1 0.033 14.5 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AAA_18 PF13238.1 GAP91943.1 - 0.055 13.7 0.1 1.9 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain ThiF PF00899.16 GAP91943.1 - 1 9.1 3.8 0.44 10.3 0.1 2.3 3 0 0 3 3 3 0 ThiF family Zn_clus PF00172.13 GAP91944.1 - 2.5e-06 27.2 10.3 3.8e-06 26.6 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyoxalase PF00903.20 GAP91945.1 - 8e-06 25.8 3.3 0.0043 17.0 0.8 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAP91945.1 - 8.9e-05 23.0 0.7 0.00038 21.0 0.1 2.0 2 0 0 2 2 2 1 Glyoxalase-like domain Acid_PPase PF12689.2 GAP91946.1 - 1.5e-54 184.1 0.0 3.7e-27 94.9 0.0 2.1 2 0 0 2 2 2 2 Acid Phosphatase HAD_2 PF13419.1 GAP91946.1 - 0.18 12.0 0.5 44 4.2 0.0 3.0 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase CRAL_TRIO PF00650.15 GAP91947.1 - 1.2e-24 86.5 0.0 1.9e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAP91947.1 - 8.4e-09 35.4 0.0 2.1e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 GAP91947.1 - 0.041 13.7 0.0 0.27 11.1 0.0 2.0 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain Pyr_redox_3 PF13738.1 GAP91948.1 - 6e-20 72.1 0.0 7e-19 68.6 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAP91948.1 - 3.9e-12 45.1 0.8 1.3e-10 40.1 0.1 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 GAP91948.1 - 3.2e-11 42.7 0.0 4.2e-08 32.5 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAP91948.1 - 4.8e-10 39.6 0.0 6.1e-09 36.0 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAP91948.1 - 4e-06 27.1 0.0 0.12 12.7 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAP91948.1 - 0.00014 21.0 0.0 0.0039 16.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 GAP91948.1 - 0.00058 19.8 0.0 0.0089 16.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAP91948.1 - 0.0029 16.7 0.0 0.025 13.6 0.0 2.4 2 1 0 2 2 2 1 Thi4 family DAO PF01266.19 GAP91948.1 - 0.0077 15.1 0.0 2.9 6.6 0.0 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 GAP91948.1 - 0.011 14.8 0.0 0.029 13.5 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 GAP91948.1 - 0.089 12.5 0.2 10 5.8 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding SSP160 PF06933.6 GAP91949.1 - 0.2 9.5 3.5 0.22 9.4 2.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Tannase PF07519.6 GAP91950.1 - 6e-71 239.5 7.7 4.2e-51 174.1 1.9 2.3 2 0 0 2 2 2 2 Tannase and feruloyl esterase MFS_1 PF07690.11 GAP91951.1 - 1.5e-45 155.4 27.0 4e-45 154.0 17.8 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily 4HBT_3 PF13622.1 GAP91951.1 - 9.5e-28 97.6 5.0 9.5e-28 97.6 3.5 2.1 2 0 0 2 2 2 1 Thioesterase-like superfamily Syntaxin-18_N PF10496.4 GAP91952.1 - 1.7e-13 50.1 0.6 6.2e-13 48.4 0.1 2.3 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 GAP91952.1 - 0.0026 17.3 1.1 0.0026 17.3 0.8 3.5 3 0 0 3 3 3 1 SNARE domain HAUS-augmin3 PF14932.1 GAP91952.1 - 8.8 5.4 14.1 0.15 11.2 1.5 2.6 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 3 Aminotran_1_2 PF00155.16 GAP91953.1 - 6.9e-86 288.4 0.0 8e-86 288.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Polysacc_deac_1 PF01522.16 GAP91954.1 - 6e-15 54.9 0.0 1.2e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 GAP91954.1 - 0.048 13.0 0.1 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) PLRV_ORF5 PF01690.12 GAP91954.1 - 2.7 7.0 23.6 4.8 6.2 16.4 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein BetaGal_dom2 PF10435.4 GAP91956.1 - 0.034 13.5 0.1 0.05 12.9 0.1 1.3 1 0 0 1 1 1 0 Beta-galactosidase, domain 2 4HBT PF03061.17 GAP91956.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Thioesterase superfamily AlaDh_PNT_N PF05222.10 GAP91957.1 - 7.1e-23 81.1 0.0 9.7e-23 80.6 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 GAP91957.1 - 4.2e-05 23.1 0.0 0.0004 19.9 0.0 2.0 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Nup54 PF13874.1 GAP91959.1 - 0.014 15.1 2.3 0.027 14.1 1.6 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 HAP1_N PF04849.8 GAP91959.1 - 0.036 13.0 5.2 0.055 12.3 3.6 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region NR_Repeat PF14046.1 GAP91959.1 - 0.082 12.6 0.1 0.39 10.4 0.0 2.1 2 0 0 2 2 2 0 Nuclear receptor repeat Med21 PF11221.3 GAP91959.1 - 0.14 12.1 4.3 0.34 10.8 3.0 1.6 1 0 0 1 1 1 0 Subunit 21 of Mediator complex DUF2570 PF10828.3 GAP91959.1 - 0.5 10.0 3.1 0.97 9.0 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) IncA PF04156.9 GAP91959.1 - 0.62 9.6 4.5 1.4 8.5 3.1 1.5 1 0 0 1 1 1 0 IncA protein AIG1 PF04548.11 GAP91960.1 - 1.9e-10 40.2 0.0 3.5e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 GAP91960.1 - 6e-07 29.4 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 GAP91960.1 - 1.8e-05 24.6 5.5 0.0051 16.6 0.1 3.1 2 2 1 3 3 3 2 Dynamin family SRPRB PF09439.5 GAP91960.1 - 0.00099 18.3 0.0 0.0021 17.3 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 GAP91960.1 - 0.0018 17.4 0.2 0.0053 15.9 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 GAP91960.1 - 0.0037 16.7 0.1 0.0091 15.4 0.0 1.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_17 PF13207.1 GAP91960.1 - 0.0088 16.8 0.4 0.028 15.2 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAP91960.1 - 0.011 15.7 0.1 0.034 14.1 0.0 1.8 1 1 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.12 GAP91960.1 - 0.012 15.3 0.8 0.077 12.8 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function DUF87 AAA_33 PF13671.1 GAP91960.1 - 0.016 15.1 0.1 0.043 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAP91960.1 - 0.028 14.5 0.1 0.099 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 GAP91960.1 - 0.032 13.2 0.3 0.12 11.3 0.0 2.0 2 1 0 2 2 2 0 Septin ABC_tran PF00005.22 GAP91960.1 - 0.083 13.1 0.5 0.51 10.6 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Miro PF08477.8 GAP91960.1 - 0.087 13.3 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_10 PF12846.2 GAP91960.1 - 0.089 12.2 0.4 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain EI24 PF07264.6 GAP91960.1 - 0.1 11.9 0.0 14 5.0 0.0 2.1 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) AAA_23 PF13476.1 GAP91960.1 - 0.11 12.8 0.9 15 5.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain IIGP PF05049.8 GAP91960.1 - 0.11 11.2 0.1 0.27 9.9 0.0 1.6 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Viral_helicase1 PF01443.13 GAP91960.1 - 0.13 11.7 0.1 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase HSP70 PF00012.15 GAP91961.1 - 1.5e-05 23.1 0.8 0.00047 18.2 0.6 2.8 1 1 0 1 1 1 1 Hsp70 protein Pyrid_oxidase_2 PF13883.1 GAP91961.1 - 0.058 13.1 0.0 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase TPR_11 PF13414.1 GAP91962.1 - 1.6e-09 37.2 0.4 5.1e-06 26.0 0.0 2.6 1 1 1 2 2 2 2 TPR repeat TPR_16 PF13432.1 GAP91962.1 - 2.2e-08 34.5 3.8 0.0022 18.5 0.8 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat SET PF00856.23 GAP91962.1 - 4.7e-08 33.4 0.0 7.2e-07 29.6 0.0 2.6 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.12 GAP91962.1 - 5e-05 22.9 0.6 0.084 12.8 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAP91962.1 - 0.0018 18.6 0.4 0.02 15.3 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAP91962.1 - 0.071 13.7 1.1 9.8 7.1 0.1 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat Bud13 PF09736.4 GAP91963.1 - 2.1e-38 131.8 0.0 4.3e-38 130.8 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex TFIIF_alpha PF05793.7 GAP91964.1 - 0.012 13.9 56.5 0.049 12.0 37.2 3.2 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PAP_assoc PF03828.14 GAP91965.1 - 1.2e-18 66.7 0.0 3.9e-12 45.9 0.0 2.8 2 0 0 2 2 2 2 Cid1 family poly A polymerase Churchill PF06573.6 GAP91965.1 - 0.046 13.7 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 Churchill protein XPG_I_2 PF12813.2 GAP91966.1 - 6.4e-46 156.8 0.0 1e-45 156.1 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 GAP91966.1 - 0.16 12.0 0.0 0.45 10.6 0.0 1.7 1 0 0 1 1 1 0 XPG I-region Pribosyltran_N PF13793.1 GAP91967.1 - 1e-40 138.0 0.0 3.1e-40 136.5 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 GAP91967.1 - 1.3e-34 119.5 0.0 2.6e-29 102.2 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 GAP91967.1 - 5.3e-07 29.4 0.1 0.0002 21.1 0.0 2.8 3 0 0 3 3 3 2 Phosphoribosyl transferase domain UPRTase PF14681.1 GAP91967.1 - 0.029 13.5 0.0 0.054 12.6 0.0 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase zf-C3HC4_3 PF13920.1 GAP91969.1 - 9.1e-07 28.4 14.0 1.6e-06 27.6 9.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SDA1 PF05285.7 GAP91969.1 - 0.42 9.8 4.6 0.72 9.0 3.2 1.3 1 0 0 1 1 1 0 SDA1 FAM24 PF15193.1 GAP91969.1 - 4.1 7.6 7.5 8.7 6.6 5.2 1.5 1 0 0 1 1 1 0 FAM24 family RNase_PH PF01138.16 GAP91970.1 - 4.5e-27 94.9 0.0 7.1e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Glyco_trans_1_4 PF13692.1 GAP91970.1 - 0.02 15.0 0.0 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferases group 1 adh_short PF00106.20 GAP91971.1 - 4.1e-35 121.1 1.1 7.2e-35 120.3 0.7 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP91971.1 - 5e-13 49.1 0.4 8.6e-13 48.3 0.3 1.4 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 GAP91971.1 - 0.011 15.5 0.9 0.025 14.3 0.6 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Lin0512_fam PF09585.5 GAP91971.1 - 0.025 14.1 0.1 0.21 11.1 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical protein (Lin0512_fam) Abhydrolase_3 PF07859.8 GAP91972.1 - 3.5e-42 144.3 0.0 5.2e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP91972.1 - 4.8e-07 29.6 0.0 6.6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP91972.1 - 5.2e-07 29.7 2.8 9.8e-07 28.8 2.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 GAP91972.1 - 6.7e-06 25.0 0.0 3.5e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_2 PF02230.11 GAP91972.1 - 0.00029 20.3 0.0 0.008 15.6 0.0 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 GAP91972.1 - 0.00044 19.5 0.0 0.043 13.0 0.0 2.6 3 0 0 3 3 3 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 GAP91972.1 - 0.028 13.6 0.1 0.13 11.5 0.1 1.9 2 0 0 2 2 2 0 Esterase PHB depolymerase TPR_12 PF13424.1 GAP91973.1 - 1.6e-22 79.1 12.3 4.7e-10 39.2 0.6 5.1 4 1 0 5 5 5 2 Tetratricopeptide repeat NB-ARC PF00931.17 GAP91973.1 - 8.8e-12 44.4 0.0 1.9e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_11 PF13414.1 GAP91973.1 - 6.5e-10 38.5 11.0 0.0012 18.4 0.3 4.7 4 1 0 4 4 4 3 TPR repeat TPR_10 PF13374.1 GAP91973.1 - 3.7e-07 29.8 1.7 0.098 12.6 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAP91973.1 - 5.6e-06 25.8 15.8 0.15 12.0 0.1 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat SPO22 PF08631.5 GAP91973.1 - 0.00028 20.0 4.6 0.00045 19.3 0.1 2.9 3 0 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like TPR_1 PF00515.23 GAP91973.1 - 0.00039 19.9 12.6 0.83 9.3 0.0 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat AAA_22 PF13401.1 GAP91973.1 - 0.00061 19.9 0.0 0.0025 17.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAP91973.1 - 0.0028 17.6 0.2 0.019 14.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain TPR_7 PF13176.1 GAP91973.1 - 0.0037 16.9 3.0 24 5.0 0.0 5.5 5 0 0 5 5 4 0 Tetratricopeptide repeat Apc3 PF12895.2 GAP91973.1 - 0.0062 16.6 9.8 0.043 13.9 0.0 4.0 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 AAA_14 PF13173.1 GAP91973.1 - 0.05 13.5 0.0 0.16 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain TPR_14 PF13428.1 GAP91973.1 - 0.055 14.1 7.9 3.1 8.6 0.1 6.0 6 1 1 7 7 6 0 Tetratricopeptide repeat DUF2203 PF09969.4 GAP91973.1 - 0.12 12.6 0.0 0.5 10.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) TPR_16 PF13432.1 GAP91973.1 - 0.2 12.4 3.8 2.4 8.9 0.0 4.2 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAP91973.1 - 0.5 10.2 7.3 5.3 7.0 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAP91973.1 - 0.64 10.3 3.3 64 4.1 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_M1 PF01433.15 GAP91974.1 - 6.8e-131 436.9 0.0 1.4e-130 435.9 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 GAP91974.1 - 3.7e-66 223.5 0.1 5.3e-66 223.0 0.1 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 GAP91974.1 - 2.2e-17 63.3 0.2 4.1e-17 62.4 0.2 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Beta-lactamase PF00144.19 GAP91975.1 - 1.9e-17 63.3 0.0 1.1e-16 60.8 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase ketoacyl-synt PF00109.21 GAP91976.1 - 2.7e-58 197.4 0.0 5.6e-58 196.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 GAP91976.1 - 4.3e-52 177.1 0.0 7e-52 176.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 GAP91976.1 - 4.4e-48 163.3 1.3 1.1e-47 161.9 0.9 1.8 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 GAP91976.1 - 2.1e-42 145.5 0.0 3.1e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 GAP91976.1 - 6e-33 114.1 2.5 1.5e-32 112.8 0.9 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAP91976.1 - 6.2e-33 113.1 0.3 4.4e-32 110.4 0.2 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 GAP91976.1 - 4.9e-14 52.0 0.2 5.5e-13 48.6 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAP91976.1 - 2.7e-12 47.6 0.0 1.1e-11 45.7 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP91976.1 - 1.6e-07 31.0 1.2 3.7e-07 29.8 0.8 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 GAP91976.1 - 2e-07 31.1 0.1 4.6e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_5 PF12695.2 GAP91977.1 - 4.2e-15 55.7 0.0 1.5e-14 54.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP91977.1 - 6.7e-13 49.0 0.1 4.5e-11 43.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAP91977.1 - 7.7e-08 32.0 0.0 1.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 GAP91977.1 - 2.3e-07 30.2 0.0 1.1e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 GAP91977.1 - 4.9e-05 22.8 0.0 6.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 GAP91977.1 - 0.0001 20.9 0.0 0.5 8.8 0.0 3.1 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 GAP91977.1 - 0.063 12.8 0.0 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold FAD_binding_4 PF01565.18 GAP91978.1 - 5.2e-15 55.1 1.0 9.2e-15 54.3 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP91978.1 - 3e-11 43.0 0.8 3e-11 43.0 0.6 1.9 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.5 GAP91978.1 - 0.0084 15.2 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding p450 PF00067.17 GAP91979.1 - 1.5e-61 208.3 0.0 1.9e-61 208.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 GAP91982.1 - 2.3e-20 73.2 5.9 9.4e-20 71.1 4.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP91982.1 - 3.8e-11 43.2 0.0 7.9e-11 42.1 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 GAP91982.1 - 5.5e-07 29.0 0.0 2e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) KR PF08659.5 GAP91982.1 - 0.001 18.7 4.3 0.011 15.4 0.6 2.3 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 GAP91982.1 - 0.0017 17.7 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Serglycin PF04360.7 GAP91982.1 - 0.0023 17.6 0.4 0.27 10.9 0.0 2.2 2 0 0 2 2 2 1 Serglycin NAD_binding_10 PF13460.1 GAP91982.1 - 0.022 14.7 0.5 0.041 13.8 0.2 1.7 2 0 0 2 2 2 0 NADH(P)-binding Saccharop_dh PF03435.13 GAP91982.1 - 0.07 12.0 0.0 0.09 11.7 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase RmlD_sub_bind PF04321.12 GAP91982.1 - 0.074 11.9 0.2 0.23 10.3 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.8 GAP91982.1 - 0.12 11.5 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Ank_2 PF12796.2 GAP91983.1 - 2.1e-23 82.4 0.0 1.2e-13 51.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAP91983.1 - 4.2e-22 76.7 0.8 2.5e-07 30.1 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 GAP91983.1 - 1.4e-19 70.0 0.3 2.6e-10 40.5 0.0 3.0 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP91983.1 - 3.1e-17 62.2 0.0 2.9e-10 40.0 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP91983.1 - 1.4e-13 49.6 0.1 0.0036 17.3 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat bZIP_1 PF00170.16 GAP91983.1 - 0.0018 18.2 7.3 0.003 17.4 5.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAP91983.1 - 0.031 14.0 5.0 0.053 13.3 3.5 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Abhydrolase_6 PF12697.2 GAP91984.1 - 3.6e-09 36.8 5.3 4.5e-09 36.5 3.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP91984.1 - 1.3e-05 24.9 1.0 1.6e-05 24.6 0.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2121 PF09894.4 GAP91985.1 - 0.38 10.0 4.2 0.32 10.2 0.5 2.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2121) tRNA_int_endo PF01974.12 GAP91986.1 - 2.6e-13 49.5 0.0 5.1e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain DUF3575 PF12099.3 GAP91986.1 - 0.028 13.4 0.0 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3575) PAXNEB PF05625.6 GAP91987.1 - 6.4e-100 334.5 0.0 7.8e-100 334.2 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein RNA_pol_Rpb8 PF03870.10 GAP91988.1 - 1.6e-32 112.5 0.0 1.8e-32 112.3 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 NUDIX PF00293.23 GAP91989.1 - 1.4e-09 37.7 0.0 2.3e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain MIF4G_like_2 PF09090.6 GAP91989.1 - 0.058 12.6 0.0 0.4 9.8 0.0 1.9 2 0 0 2 2 2 0 MIF4G like DUF775 PF05603.7 GAP91990.1 - 3.3e-48 163.8 0.0 3.7e-48 163.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Saccharop_dh PF03435.13 GAP91990.1 - 0.13 11.2 0.6 0.16 10.9 0.4 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase GDA1_CD39 PF01150.12 GAP91991.1 - 5.5e-102 341.4 0.0 7.5e-102 341.0 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Amidoligase_2 PF12224.3 GAP91992.1 - 3.9e-21 75.8 0.0 6.9e-15 55.3 0.0 2.9 2 1 0 2 2 2 2 Putative amidoligase enzyme HET PF06985.6 GAP91993.1 - 1.6e-33 115.8 0.4 2.9e-33 114.9 0.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AA_permease PF00324.16 GAP91994.1 - 5.5e-131 437.1 47.5 6.9e-131 436.8 32.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAP91994.1 - 7.6e-36 123.5 53.9 9.7e-36 123.2 37.3 1.1 1 0 0 1 1 1 1 Amino acid permease HET PF06985.6 GAP91995.1 - 0.0014 18.7 2.5 0.0014 18.7 1.7 2.2 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) His_Phos_1 PF00300.17 GAP91996.1 - 5.6e-24 85.0 0.0 6.7e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) p450 PF00067.17 GAP91997.1 - 1.3e-21 76.6 0.0 1.7e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Isochorismatase PF00857.15 GAP91998.1 - 2.5e-18 66.6 0.0 2.9e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family GMC_oxred_N PF00732.14 GAP91999.1 - 1.8e-47 161.9 0.0 2.5e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAP91999.1 - 3.5e-39 134.3 0.0 7.4e-39 133.3 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase PhyH PF05721.8 GAP91999.1 - 6.5e-24 85.1 0.0 1e-23 84.4 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DAO PF01266.19 GAP91999.1 - 6e-08 31.9 0.0 6.8e-06 25.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAP91999.1 - 6.4e-05 21.9 0.1 0.0056 15.5 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 GAP91999.1 - 0.00043 20.2 0.3 0.0018 18.2 0.2 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAP91999.1 - 0.0034 16.3 0.0 0.0056 15.6 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein 2OG-FeII_Oxy_3 PF13640.1 GAP91999.1 - 0.044 14.2 0.0 0.25 11.8 0.0 2.3 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily HI0933_like PF03486.9 GAP91999.1 - 0.05 12.0 0.1 0.13 10.6 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.9 GAP91999.1 - 0.059 13.2 0.1 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 GAP92000.1 - 3.8e-37 127.8 50.7 9.5e-37 126.5 33.9 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAP92000.1 - 8.5e-15 53.9 6.2 1.6e-14 53.0 4.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAP92000.1 - 1.1e-07 30.8 7.1 1.1e-07 30.8 4.9 3.5 1 1 2 3 3 3 1 Sugar (and other) transporter DUF3522 PF12036.3 GAP92000.1 - 0.063 13.0 1.3 0.53 10.0 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3522) Phage_holin_5 PF06946.6 GAP92000.1 - 2.8 8.1 11.2 0.091 12.9 0.6 3.3 3 0 0 3 3 3 0 Phage holin DPPIV_N PF00930.16 GAP92005.1 - 1e-104 349.9 0.1 1.4e-104 349.4 0.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 GAP92005.1 - 1.2e-54 184.7 3.7 2.2e-54 183.9 2.6 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAP92005.1 - 2.3e-08 33.9 0.2 4.6e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP92005.1 - 1e-06 28.7 0.1 1.5e-05 24.9 0.0 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 GAP92005.1 - 3e-06 26.8 3.4 2.6e-05 23.7 1.4 2.3 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) YbjQ_1 PF01906.12 GAP92006.1 - 2.2e-27 95.5 0.1 2.6e-27 95.3 0.1 1.0 1 0 0 1 1 1 1 Putative heavy-metal-binding Cullin PF00888.17 GAP92011.1 - 2e-120 403.1 0.0 2.5e-120 402.7 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 GAP92011.1 - 1.4e-25 88.8 0.6 4.4e-25 87.2 0.4 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain zf-DNL PF05180.7 GAP92012.1 - 1.1e-26 92.3 0.1 1.7e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 GAP92012.1 - 0.00093 18.6 0.3 0.0016 17.8 0.2 1.3 1 0 0 1 1 1 1 CSL zinc finger DRIM PF07539.7 GAP92013.1 - 1.6e-40 137.8 0.1 5.2e-40 136.1 0.0 2.0 1 0 0 1 1 1 1 Down-regulated in metastasis Arm PF00514.18 GAP92013.1 - 0.022 14.5 0.3 73 3.4 0.0 6.0 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat HEAT PF02985.17 GAP92013.1 - 0.039 14.0 7.7 7.3 6.9 0.1 7.4 7 1 0 7 7 7 0 HEAT repeat CwfJ_C_2 PF04676.9 GAP92015.1 - 9.4e-24 83.7 0.3 2e-23 82.7 0.2 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.10 GAP92015.1 - 1.9e-20 72.7 0.0 3.7e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DNA_pol_phi PF04931.8 GAP92016.1 - 1.3e-43 148.9 27.4 3.5e-42 144.1 19.0 2.6 1 1 0 1 1 1 1 DNA polymerase phi DUF1676 PF07898.8 GAP92016.1 - 0.0092 16.2 3.6 0.039 14.2 2.5 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1676) RRM_1 PF00076.17 GAP92017.1 - 0.00039 19.9 0.0 0.0012 18.4 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans_2 PF11951.3 GAP92019.1 - 3.5e-07 29.1 0.2 9.8e-07 27.6 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP92019.1 - 9.9e-07 28.5 10.1 1.8e-06 27.7 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med9 PF07544.8 GAP92020.1 - 0.1 12.3 0.9 0.18 11.5 0.6 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Ferrochelatase PF00762.14 GAP92021.1 - 0.075 11.9 0.0 0.088 11.7 0.0 1.1 1 0 0 1 1 1 0 Ferrochelatase Chromo PF00385.19 GAP92022.1 - 8.9e-07 28.4 1.5 2.1e-06 27.2 0.7 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain AT_hook PF02178.14 GAP92022.1 - 1.3 8.9 8.9 0.37 10.6 1.9 2.9 2 0 0 2 2 2 0 AT hook motif Proteasome PF00227.21 GAP92023.1 - 1.6e-43 148.1 0.4 1.8e-29 102.3 0.0 2.8 3 0 0 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.4 GAP92023.1 - 1.8e-11 43.1 0.0 3.6e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Rhodanese PF00581.15 GAP92024.1 - 2.1e-11 44.1 0.0 4.2e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain CBM_1 PF00734.13 GAP92025.1 - 7.6e-11 41.4 16.6 3e-10 39.5 11.5 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_16 PF00722.16 GAP92025.1 - 2e-10 40.2 2.7 2e-10 40.2 1.8 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Dynamin_N PF00350.18 GAP92026.1 - 1.6e-14 54.0 2.5 2.6e-14 53.4 0.0 2.7 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 GAP92026.1 - 7.2e-06 25.9 0.0 0.00016 21.6 0.0 2.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF4164 PF13747.1 GAP92026.1 - 0.00011 22.3 1.1 0.00011 22.3 0.7 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF4164) ABC_tran PF00005.22 GAP92026.1 - 0.00049 20.4 1.2 0.0022 18.2 0.0 2.7 2 1 0 2 2 2 1 ABC transporter DUF258 PF03193.11 GAP92026.1 - 0.00098 18.3 0.0 0.012 14.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 GAP92026.1 - 0.0086 16.5 0.0 0.045 14.2 0.0 2.3 1 0 0 1 1 1 1 Miro-like protein AAA_17 PF13207.1 GAP92026.1 - 0.022 15.5 1.4 0.21 12.4 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 GAP92026.1 - 0.033 14.3 0.4 0.95 9.6 0.0 3.6 3 1 1 4 4 4 0 AAA domain ArgK PF03308.11 GAP92026.1 - 0.052 12.3 0.9 0.29 9.8 0.1 2.5 2 1 1 3 3 3 0 ArgK protein AAA_29 PF13555.1 GAP92026.1 - 0.066 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mfp-3 PF04202.8 GAP92026.1 - 0.21 11.7 1.1 0.59 10.3 0.8 1.7 1 0 0 1 1 1 0 Foot protein 3 AAA_16 PF13191.1 GAP92026.1 - 0.35 10.8 0.0 0.35 10.8 0.0 3.6 6 0 0 6 6 6 0 AAA ATPase domain DUF1319 PF07028.6 GAP92026.1 - 1.1 9.4 11.1 7.7 6.7 0.6 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1319) DegS PF05384.6 GAP92026.1 - 1.3 8.1 11.7 0.12 11.6 0.2 3.5 3 0 0 3 3 3 0 Sensor protein DegS DUF4200 PF13863.1 GAP92026.1 - 2.9 7.8 17.8 0.52 10.2 0.6 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Syntaxin-6_N PF09177.6 GAP92026.1 - 5.3 7.5 16.8 6.7 7.1 0.7 5.3 5 0 0 5 5 5 0 Syntaxin 6, N-terminal PRA-PH PF01503.12 GAP92026.1 - 9.7 6.5 9.2 3 8.1 0.1 4.0 4 0 0 4 4 4 0 Phosphoribosyl-ATP pyrophosphohydrolase Cytochrom_B561 PF03188.11 GAP92027.1 - 0.077 12.8 1.4 0.14 12.0 1.0 1.3 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 IFR3_antag PF14754.1 GAP92027.1 - 0.12 11.3 0.1 0.17 10.8 0.1 1.1 1 0 0 1 1 1 0 Papain-like auto-proteinase DUF4307 PF14155.1 GAP92027.1 - 0.57 9.9 3.9 1 9.1 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) RRM_1 PF00076.17 GAP92028.1 - 9.1e-49 162.9 0.0 1.4e-16 59.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP92028.1 - 7.2e-28 96.3 0.0 6.6e-10 38.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP92028.1 - 1.4e-22 79.2 0.0 1.4e-08 34.4 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAP92028.1 - 1.1e-06 28.4 0.0 0.00016 21.4 0.0 3.0 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 GAP92028.1 - 2.3e-05 24.0 0.0 0.0036 17.0 0.0 3.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif TauD PF02668.11 GAP92031.1 - 9.6e-55 186.0 1.6 1.2e-54 185.6 1.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family NMD3 PF04981.8 GAP92032.1 - 1.8e-57 194.2 1.1 3.1e-57 193.4 0.7 1.4 1 0 0 1 1 1 1 NMD3 family zinc_ribbon_6 PF14599.1 GAP92032.1 - 0.0027 17.4 1.8 0.7 9.7 0.1 2.8 2 0 0 2 2 2 2 Zinc-ribbon Trypsin PF00089.21 GAP92033.1 - 8.5e-07 28.7 0.0 1.8e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 GAP92033.1 - 7.9e-06 25.8 0.0 1.6e-05 24.8 0.0 1.5 2 0 0 2 2 2 1 Trypsin-like peptidase domain Peptidase_C4 PF00863.14 GAP92033.1 - 0.0054 15.7 0.0 0.0085 15.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C4 Peptidase_M35 PF02102.10 GAP92034.1 - 1e-66 225.0 9.9 1.1e-66 224.8 6.9 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 GAP92034.1 - 5.9e-05 23.6 2.5 5.9e-05 23.6 0.7 1.7 1 1 1 2 2 2 1 Lysine-specific metallo-endopeptidase NPCBM_assoc PF10633.4 GAP92034.1 - 0.03 14.3 1.7 1.1 9.3 0.0 2.7 3 0 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Bim_N PF06773.6 GAP92034.1 - 0.053 13.2 2.4 0.82 9.4 0.1 2.6 2 0 0 2 2 2 0 Bim protein N-terminus DUF4232 PF14016.1 GAP92035.1 - 0.016 14.8 2.7 0.03 13.9 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4232) Glyco_hydro_76 PF03663.9 GAP92036.1 - 4.2e-140 467.3 7.3 5.7e-140 466.8 5.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Aminotran_1_2 PF00155.16 GAP92036.1 - 2.5e-42 145.1 0.0 3e-34 118.5 0.0 2.2 1 1 1 2 2 2 2 Aminotransferase class I and II Aminotran_MocR PF12897.2 GAP92036.1 - 0.013 14.0 0.0 0.043 12.3 0.0 1.8 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase Tankyrase_bdg_C PF15327.1 GAP92037.1 - 0.04 14.0 0.8 0.046 13.8 0.5 1.3 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain Myc_N PF01056.13 GAP92037.1 - 0.82 8.7 9.5 0.96 8.5 6.4 1.3 1 1 0 1 1 1 0 Myc amino-terminal region Spt5_N PF11942.3 GAP92037.1 - 2.3 8.9 11.5 0.16 12.6 2.8 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Ribosomal_60s PF00428.14 GAP92037.1 - 6.5 7.2 16.7 0.79 10.1 7.7 2.1 2 1 0 2 2 2 0 60s Acidic ribosomal protein APC_CDC26 PF10471.4 GAP92038.1 - 0.055 14.2 8.9 2.6 8.8 0.4 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Suf PF05843.9 GAP92038.1 - 1.9 8.1 9.7 4.2 7.0 1.7 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) YihI PF04220.7 GAP92038.1 - 9.7 5.4 12.4 0.57 9.4 1.9 2.2 2 0 0 2 2 2 0 Der GTPase activator (YihI) DUF883 PF05957.8 GAP92039.1 - 0.12 12.8 0.2 0.34 11.3 0.1 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Beta-lactamase PF00144.19 GAP92040.1 - 1.7e-44 152.1 0.0 2.9e-44 151.4 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 GAP92040.1 - 7.8e-14 51.3 0.0 1.8e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Ank_2 PF12796.2 GAP92041.1 - 8.8e-06 25.9 0.2 0.55 10.6 0.1 4.1 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) DUF2119 PF09892.4 GAP92041.1 - 0.014 14.7 0.0 0.03 13.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) NACHT PF05729.7 GAP92041.1 - 0.015 14.9 0.1 0.08 12.5 0.1 2.3 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 GAP92041.1 - 0.041 13.8 0.2 0.31 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Ank_3 PF13606.1 GAP92041.1 - 0.17 12.2 2.1 85 3.8 0.0 5.0 6 0 0 6 6 6 0 Ankyrin repeat Ank PF00023.25 GAP92041.1 - 0.36 10.7 3.5 18 5.3 0.1 4.6 5 0 0 5 5 5 0 Ankyrin repeat DUF2217 PF10265.4 GAP92042.1 - 7.6 5.1 8.7 14 4.3 6.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) P_proprotein PF01483.15 GAP92043.1 - 0.013 15.2 0.1 0.035 13.8 0.0 1.7 2 0 0 2 2 2 0 Proprotein convertase P-domain Abhydrolase_6 PF12697.2 GAP92044.1 - 1.6e-18 67.4 5.3 1.6e-18 67.4 3.7 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP92044.1 - 1.2e-11 44.5 0.0 2.2e-10 40.4 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP92044.1 - 3.7e-10 39.7 1.1 1e-09 38.2 0.8 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAP92044.1 - 4.7e-07 29.5 0.1 1e-06 28.5 0.1 1.5 1 0 0 1 1 1 1 Putative lysophospholipase BAAT_C PF08840.6 GAP92044.1 - 0.0092 15.7 0.0 3.6 7.2 0.0 2.2 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 GAP92044.1 - 0.013 14.7 0.0 0.03 13.6 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Esterase PF00756.15 GAP92044.1 - 0.078 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.15 GAP92044.1 - 0.15 12.2 0.4 0.24 11.5 0.3 1.3 1 0 0 1 1 1 0 Thioesterase domain Aldo_ket_red PF00248.16 GAP92045.1 - 4.6e-49 166.7 0.0 5.3e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF202 PF02656.10 GAP92046.1 - 2.4e-24 85.3 0.8 2.4e-24 85.3 0.6 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF202) DUF2975 PF11188.3 GAP92046.1 - 0.13 11.9 1.8 0.28 10.9 1.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) AAA_11 PF13086.1 GAP92047.1 - 2.5e-58 197.4 0.0 4.3e-58 196.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 GAP92047.1 - 9.8e-57 191.5 0.0 8e-56 188.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAP92047.1 - 2.4e-12 46.4 0.3 1.9e-11 43.5 0.0 2.7 3 0 0 3 3 2 1 Part of AAA domain AAA_30 PF13604.1 GAP92047.1 - 1e-10 41.5 0.0 7.3e-09 35.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 GAP92047.1 - 1.3e-06 28.1 0.0 0.18 11.3 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 GAP92047.1 - 1.4e-06 27.5 0.1 8.5e-06 24.9 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 GAP92047.1 - 2.2e-05 24.3 0.0 7.3e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 GAP92047.1 - 0.00026 21.1 0.1 0.0085 16.2 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAP92047.1 - 0.00098 19.1 0.0 0.0024 17.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 GAP92047.1 - 0.0013 18.1 0.2 0.011 15.2 0.0 2.5 2 1 1 3 3 3 1 AAA domain UvrD-helicase PF00580.16 GAP92047.1 - 0.0028 17.0 0.0 0.0099 15.2 0.0 1.9 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA PF00004.24 GAP92047.1 - 0.0044 17.2 0.0 0.047 13.9 0.0 2.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Flavi_DEAD PF07652.9 GAP92047.1 - 0.0079 15.9 0.0 0.046 13.4 0.0 2.3 2 0 0 2 2 2 1 Flavivirus DEAD domain PhoH PF02562.11 GAP92047.1 - 0.0087 15.3 0.0 0.39 9.9 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein Zot PF05707.7 GAP92047.1 - 0.009 15.4 0.1 0.047 13.1 0.0 2.3 3 0 0 3 3 3 1 Zonular occludens toxin (Zot) T2SE PF00437.15 GAP92047.1 - 0.014 14.2 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 GAP92047.1 - 0.019 14.4 0.0 0.058 12.8 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family UvrD_C_2 PF13538.1 GAP92047.1 - 0.02 15.0 0.0 0.69 10.0 0.0 2.5 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain UvrD_C PF13361.1 GAP92047.1 - 0.029 13.8 0.1 9.4 5.5 0.0 2.6 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain AAA_17 PF13207.1 GAP92047.1 - 0.034 14.9 0.4 0.11 13.2 0.3 2.0 1 1 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 GAP92047.1 - 0.041 12.5 0.0 0.081 11.5 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.12 GAP92047.1 - 0.052 12.9 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein PIF1 PF05970.9 GAP92047.1 - 0.057 12.3 0.0 1.7 7.5 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase Zeta_toxin PF06414.7 GAP92047.1 - 0.064 12.3 0.0 0.17 10.9 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.2 GAP92047.1 - 0.078 12.3 0.0 0.27 10.6 0.0 1.9 1 1 1 2 2 2 0 AAA-like domain ATP-synt_ab PF00006.20 GAP92047.1 - 0.12 11.8 0.0 0.44 10.0 0.0 1.9 1 1 1 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Peptidase_M28 PF04389.12 GAP92049.1 - 4.9e-27 94.8 0.0 1.2e-26 93.5 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 GAP92049.1 - 2.7e-05 23.7 0.0 4.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 fn3 PF00041.16 GAP92049.1 - 0.005 16.9 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain Peptidase_M42 PF05343.9 GAP92049.1 - 0.0074 15.0 0.0 0.024 13.4 0.0 1.8 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase BBE PF08031.7 GAP92050.1 - 4e-11 42.6 0.1 1.2e-10 41.1 0.0 1.9 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 GAP92050.1 - 0.15 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD_binding_4 PF01565.18 GAP92051.1 - 8.4e-17 60.9 3.3 1.9e-16 59.7 2.3 1.6 1 1 0 1 1 1 1 FAD binding domain DSPn PF14671.1 GAP92052.1 - 2.7e-43 147.3 0.0 1.9e-40 138.1 0.0 3.1 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 GAP92052.1 - 1.1e-15 57.4 0.0 2.1e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAP92052.1 - 8.4e-07 28.5 0.3 3.5e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 GAP92052.1 - 0.016 15.2 0.0 0.042 13.9 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate Pcc1 PF09341.5 GAP92053.1 - 1.6e-25 88.9 1.1 2.1e-25 88.5 0.7 1.2 1 0 0 1 1 1 1 Transcription factor Pcc1 DUF1676 PF07898.8 GAP92053.1 - 0.11 12.7 0.3 0.14 12.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) WW PF00397.21 GAP92054.1 - 6.1e-10 38.7 0.2 2.3e-09 36.9 0.1 2.1 1 0 0 1 1 1 1 WW domain PhoD PF09423.5 GAP92054.1 - 6.2e-05 21.7 0.7 6.2e-05 21.7 0.5 2.9 3 0 0 3 3 3 2 PhoD-like phosphatase PMM PF03332.8 GAP92055.1 - 3.2e-99 330.9 0.0 3.7e-99 330.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase S6PP PF05116.8 GAP92055.1 - 0.013 14.8 0.0 1.6 7.9 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.7 GAP92055.1 - 0.042 13.4 0.0 6.1 6.3 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Na_Ca_ex PF01699.19 GAP92057.1 - 6.2e-42 142.5 25.9 7.7e-23 80.6 2.7 3.9 4 1 1 5 5 5 2 Sodium/calcium exchanger protein SPC12 PF06645.8 GAP92057.1 - 0.00076 19.2 0.1 0.00076 19.2 0.1 4.1 6 0 0 6 6 6 2 Microsomal signal peptidase 12 kDa subunit (SPC12) CHCH PF06747.8 GAP92058.1 - 7.2e-06 25.7 2.5 1.3e-05 24.9 1.4 1.7 1 1 1 2 2 2 1 CHCH domain DUF1903 PF08991.5 GAP92058.1 - 1.4e-05 25.0 1.9 2.1e-05 24.5 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) UPF0203 PF05254.7 GAP92058.1 - 0.056 13.3 4.9 0.32 10.8 3.1 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Pet191_N PF10203.4 GAP92058.1 - 0.11 12.5 2.8 0.18 11.8 2.0 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 NatB_MDM20 PF09797.4 GAP92059.1 - 4.4e-30 104.6 0.1 6.8e-30 103.9 0.1 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit Ilm1 PF10311.4 GAP92060.1 - 8.8e-43 145.6 0.1 9.9e-43 145.4 0.1 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Prenyltrans PF00432.16 GAP92061.1 - 5.1e-40 134.6 0.4 1.1e-08 34.4 0.0 5.9 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 GAP92061.1 - 2e-19 70.0 0.0 1.9e-12 47.5 0.0 3.6 2 1 1 3 3 3 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 GAP92061.1 - 3.7e-05 23.6 0.0 0.19 11.7 0.0 3.9 2 1 0 3 3 3 1 Prenyltransferase-like TRAPPC10 PF12584.3 GAP92062.1 - 4.7e-25 87.8 0.0 8.9e-25 86.9 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.3 GAP92062.1 - 0.00056 19.4 0.2 0.00098 18.6 0.1 1.3 1 0 0 1 1 1 1 Foie gras liver health family 1 IF-2B PF01008.12 GAP92063.1 - 2.9e-56 190.5 0.1 3.8e-54 183.5 0.1 2.0 1 1 0 1 1 1 1 Initiation factor 2 subunit family Peptidase_M20 PF01546.23 GAP92064.1 - 3.7e-17 62.4 0.2 6.4e-17 61.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAP92064.1 - 7.7e-17 61.0 0.0 1.3e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 GAP92064.1 - 0.0012 18.6 0.2 0.002 17.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 Pkinase PF00069.20 GAP92065.1 - 1.5e-67 227.4 0.0 2.2e-67 226.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP92065.1 - 3.7e-41 140.8 0.0 5.4e-40 137.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP92065.1 - 2.9e-08 33.0 0.0 1.5e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 GAP92065.1 - 0.001 18.8 3.4 0.064 12.9 0.1 3.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 GAP92065.1 - 0.011 14.7 0.0 0.033 13.2 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 GAP92065.1 - 0.13 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.15 GAP92065.1 - 0.13 11.8 0.5 0.27 10.7 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase p450 PF00067.17 GAP92066.1 - 1e-65 222.1 0.0 1.4e-65 221.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF977 PF06163.6 GAP92066.1 - 0.043 13.5 0.3 4.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF977) Mito_carr PF00153.22 GAP92068.1 - 5.3e-41 138.2 4.0 1.1e-17 63.5 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Trypsin PF00089.21 GAP92069.1 - 6.4e-10 38.9 0.1 1.8e-09 37.5 0.0 1.6 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 GAP92069.1 - 4.6e-08 33.0 0.0 8.1e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_C3 PF00548.15 GAP92069.1 - 0.035 13.9 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) OmdA PF13376.1 GAP92070.1 - 1.9e-18 65.8 0.3 3.7e-18 64.9 0.2 1.5 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated SWIB PF02201.13 GAP92071.1 - 1.1e-26 92.2 0.3 2.5e-26 91.1 0.2 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 GAP92071.1 - 6.6e-13 48.2 0.6 1.3e-12 47.2 0.4 1.5 1 0 0 1 1 1 1 DEK C terminal domain Pkinase PF00069.20 GAP92073.1 - 6.9e-27 94.2 0.0 2.9e-26 92.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP92073.1 - 9.6e-12 44.5 0.0 3.9e-11 42.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAP92073.1 - 0.015 15.0 0.2 0.034 13.8 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF1376 PF07120.6 GAP92073.1 - 0.017 15.2 0.1 0.042 13.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1376) PBP_GOBP PF01395.17 GAP92073.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 PBP/GOBP family Pkinase PF00069.20 GAP92074.1 - 1.1e-43 149.2 0.0 1.7e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 GAP92074.1 - 8.4e-39 132.3 0.0 1.6e-38 131.4 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 GAP92074.1 - 2.4e-23 82.5 0.0 5.6e-22 78.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 GAP92074.1 - 4.3e-06 25.9 0.3 0.00065 19.1 0.0 3.2 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_2 PF13360.1 GAP92074.1 - 9.3e-05 21.9 0.2 0.00075 19.0 0.1 2.4 2 1 0 2 2 2 1 PQQ-like domain APH PF01636.18 GAP92074.1 - 0.0065 16.2 0.1 0.02 14.6 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 GAP92074.1 - 0.039 13.0 0.0 0.082 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 GAP92074.1 - 0.052 12.8 0.0 0.091 12.0 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL VID27 PF08553.5 GAP92075.1 - 3.4 5.7 8.8 5.9 4.9 6.1 1.3 1 0 0 1 1 1 0 VID27 cytoplasmic protein FA_desaturase PF00487.19 GAP92076.1 - 1.1e-26 93.8 11.8 1.8e-26 93.1 8.2 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 GAP92076.1 - 3.8e-06 26.9 0.0 7.2e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Arteri_Gl PF00951.13 GAP92076.1 - 0.017 14.7 0.3 0.032 13.8 0.2 1.5 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein RabGAP-TBC PF00566.13 GAP92077.1 - 2.7e-27 95.6 0.0 5.2e-27 94.7 0.0 1.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain eIF2A PF08662.6 GAP92078.1 - 6.1e-29 101.1 0.7 2.8e-15 56.5 0.0 4.0 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A RRM_5 PF13893.1 GAP92078.1 - 2e-06 27.5 0.0 4.5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP92078.1 - 7.7e-05 22.5 0.0 0.00019 21.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAP92078.1 - 0.0023 17.5 0.0 0.005 16.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 GAP92078.1 - 0.028 14.2 0.1 32 4.6 0.0 3.8 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF2497 PF10691.4 GAP92078.1 - 0.16 11.9 2.2 0.7 9.9 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) DUF3936 PF13072.1 GAP92078.1 - 0.24 10.8 1.1 0.49 9.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3936) Cpn60_TCP1 PF00118.19 GAP92079.1 - 1.4e-122 409.8 9.0 1.5e-122 409.6 6.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family p450 PF00067.17 GAP92080.1 - 6.1e-43 146.9 0.0 8.3e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ESR1_C PF12743.2 GAP92080.1 - 0.15 11.6 0.1 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal Methyltransf_2 PF00891.13 GAP92082.1 - 2.3e-30 105.5 0.0 3.2e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase HTH_IclR PF09339.5 GAP92082.1 - 0.00027 20.4 0.0 0.00067 19.1 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.1 GAP92082.1 - 0.0036 16.6 0.0 0.0064 15.8 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Tnp_ISL3 PF13542.1 GAP92082.1 - 0.022 13.9 0.0 0.072 12.2 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 TFIIE_alpha PF02002.12 GAP92082.1 - 0.023 14.1 0.0 0.048 13.1 0.0 1.5 1 0 0 1 1 1 0 TFIIE alpha subunit CheR PF01739.13 GAP92082.1 - 0.04 13.2 0.0 0.077 12.2 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain HTH_AsnC-type PF13404.1 GAP92082.1 - 0.071 12.6 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain MarR_2 PF12802.2 GAP92082.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 MarR family Methyltransf_2 PF00891.13 GAP92083.1 - 3.2e-21 75.6 0.0 5e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase MoaE PF02391.12 GAP92084.1 - 7.6e-34 116.0 0.0 9.3e-34 115.7 0.0 1.1 1 0 0 1 1 1 1 MoaE protein OPT PF03169.10 GAP92085.1 - 1.1e-175 585.6 47.5 1.3e-175 585.3 33.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MmgE_PrpD PF03972.9 GAP92086.1 - 1.1e-146 488.4 0.0 1.5e-146 488.0 0.0 1.1 1 0 0 1 1 1 1 MmgE/PrpD family SH3_1 PF00018.23 GAP92087.1 - 9.3e-15 53.7 0.2 1.5e-14 53.1 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAP92087.1 - 3.4e-12 45.7 0.1 5.1e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAP92087.1 - 6.1e-11 41.6 0.0 1e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Nucleoplasmin PF03066.10 GAP92088.1 - 0.046 13.2 11.2 2 7.9 0.1 3.5 3 0 0 3 3 3 0 Nucleoplasmin SR-25 PF10500.4 GAP92088.1 - 0.1 12.0 2.1 0.18 11.2 1.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BNIP3 PF06553.7 GAP92088.1 - 0.15 11.4 0.4 0.24 10.7 0.2 1.2 1 0 0 1 1 1 0 BNIP3 PBP1_TM PF14812.1 GAP92088.1 - 0.46 10.8 22.3 1.3 9.3 1.4 4.1 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AF1Q PF15017.1 GAP92088.1 - 0.96 9.3 11.3 0.75 9.7 0.1 3.4 3 0 0 3 3 3 0 Drug resistance and apoptosis regulator Exo_endo_phos PF03372.18 GAP92089.1 - 1.9e-13 50.9 7.7 3.2e-13 50.2 5.4 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.20 GAP92090.1 - 1.4e-38 132.5 0.0 1.7e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP92090.1 - 7.7e-14 51.3 0.0 1.1e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAP92090.1 - 1.6e-05 24.7 0.0 0.0016 18.2 0.0 2.4 1 1 0 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 GAP92090.1 - 0.051 12.3 0.1 0.077 11.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RHIM PF12721.2 GAP92091.1 - 0.17 12.3 4.4 0.59 10.5 3.0 2.0 1 0 0 1 1 1 0 RIP homotypic interaction motif TPPK_C PF12555.3 GAP92091.1 - 4.2 7.1 6.1 9.1 6.0 4.2 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal HET PF06985.6 GAP92092.1 - 2e-20 73.3 0.0 4.6e-16 59.2 0.0 2.6 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF3956 PF13104.1 GAP92093.1 - 0.037 13.5 0.6 0.084 12.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) DUF3188 PF11384.3 GAP92093.1 - 0.64 9.6 5.2 4.9 6.8 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3188) DUF202 PF02656.10 GAP92093.1 - 9.7 6.4 10.3 3.1 8.1 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF202) Mpv17_PMP22 PF04117.7 GAP92095.1 - 4.3e-15 55.0 1.6 4.3e-15 55.0 1.1 2.3 2 0 0 2 2 2 1 Mpv17 / PMP22 family YIF1 PF03878.10 GAP92096.1 - 1.3e-72 243.8 1.4 1.6e-72 243.5 1.0 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 GAP92096.1 - 0.0019 17.7 4.8 0.0019 17.7 3.4 1.7 2 0 0 2 2 2 1 Yip1 domain SRP-alpha_N PF04086.8 GAP92097.1 - 4.6e-70 236.1 0.0 6.2e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 GAP92097.1 - 2.2e-48 164.3 0.2 3.4e-46 157.1 0.1 2.3 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ArgK PF03308.11 GAP92097.1 - 1.5e-06 27.1 0.1 3.3e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 ArgK protein SRP54_N PF02881.14 GAP92097.1 - 1.8e-06 27.9 0.9 4.9e-06 26.5 0.2 2.1 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 GAP92097.1 - 1.1e-05 24.9 0.1 2.5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 GAP92097.1 - 0.0029 17.3 0.3 0.027 14.1 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 GAP92097.1 - 0.0091 15.9 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 GAP92097.1 - 0.011 16.0 0.2 0.075 13.3 0.0 2.3 3 0 0 3 3 3 0 ABC transporter AAA_30 PF13604.1 GAP92097.1 - 0.017 14.7 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 GAP92097.1 - 0.028 13.5 0.0 0.076 12.0 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 GAP92097.1 - 0.048 13.8 0.0 0.66 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 GAP92097.1 - 0.13 12.1 0.0 0.41 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Peptidase_A4 PF01828.12 GAP92098.1 - 5.5e-19 68.0 3.0 1.6e-18 66.5 1.0 1.9 2 0 0 2 2 2 1 Peptidase A4 family IBR PF01485.16 GAP92099.1 - 1.3e-10 40.9 30.7 3.1e-06 26.9 3.4 4.1 3 1 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 GAP92099.1 - 0.00011 21.9 6.7 0.00011 21.9 4.6 3.4 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 GAP92099.1 - 0.0011 18.6 6.9 0.0011 18.6 4.8 3.8 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 GAP92099.1 - 0.01 15.5 2.9 0.044 13.5 2.0 2.1 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.20 GAP92099.1 - 0.01 15.4 7.3 0.01 15.4 5.0 3.6 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L14e PF01929.12 GAP92100.1 - 6.6e-24 84.0 2.6 9.8e-24 83.5 1.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 GAP92100.1 - 4.2e-06 26.2 0.1 7.2e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 KOW motif NAC PF01849.13 GAP92101.1 - 1.1e-25 88.9 0.1 1.2e-24 85.5 0.0 2.1 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 GAP92101.1 - 0.0012 18.6 0.2 0.0029 17.4 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain PBP1_TM PF14812.1 GAP92101.1 - 1.6 9.1 11.9 1.3 9.4 3.3 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Daxx PF03344.10 GAP92101.1 - 1.9 6.8 15.2 0.7 8.3 6.7 2.0 2 0 0 2 2 2 0 Daxx Family Packaging_FI PF14000.1 GAP92101.1 - 3.4 7.8 11.9 0.59 10.3 0.1 2.4 2 1 0 2 2 2 0 DNA packaging protein FI Pox_RNA_Pol_19 PF05320.7 GAP92101.1 - 5.6 6.6 12.2 15 5.2 5.1 2.2 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Bd3614_N PF14442.1 GAP92101.1 - 8.4 6.3 12.1 2.8 7.9 3.5 2.4 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal Mt_ATP-synt_D PF05873.7 GAP92102.1 - 5e-16 58.7 1.6 6.5e-16 58.3 1.1 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) TRADD_N PF09034.5 GAP92102.1 - 0.049 13.6 0.1 0.074 13.0 0.1 1.4 1 0 0 1 1 1 0 TRADD, N-terminal domain T2SM_b PF10741.4 GAP92102.1 - 0.096 12.3 0.5 1.9 8.1 0.0 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b BLOC1_2 PF10046.4 GAP92102.1 - 0.74 9.9 5.2 0.55 10.4 1.5 1.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 F-box-like PF12937.2 GAP92103.1 - 0.021 14.5 0.2 0.33 10.7 0.0 2.6 2 0 0 2 2 2 0 F-box-like Luteo_PO PF04662.8 GAP92103.1 - 0.091 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Luteovirus P0 protein EAF PF09816.4 GAP92104.1 - 1.4e-15 57.1 1.1 2.5e-15 56.3 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor Daxx PF03344.10 GAP92104.1 - 0.29 9.5 29.4 0.41 9.0 20.4 1.3 1 0 0 1 1 1 0 Daxx Family Adaptin_binding PF10199.4 GAP92104.1 - 5 7.4 22.1 1.2e+03 -0.4 15.1 2.7 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF1183 PF06682.7 GAP92105.1 - 0.008 15.8 4.1 0.0091 15.6 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) zf-C2H2 PF00096.21 GAP92106.1 - 7.3e-07 29.1 20.2 0.0073 16.5 1.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP92106.1 - 3.5e-06 26.9 18.5 0.012 15.9 0.8 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger Rick_17kDa_Anti PF05433.10 GAP92106.1 - 0.97 9.1 5.8 1.8 8.3 4.0 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 GAP92106.1 - 1.1 8.9 4.3 2.3 7.9 3.0 1.5 1 0 0 1 1 1 0 Glycine zipper zf-H2C2_2 PF13465.1 GAP92106.1 - 4.2 7.8 21.4 10 6.5 0.8 4.3 4 0 0 4 4 4 0 Zinc-finger double domain Ogr_Delta PF04606.7 GAP92106.1 - 7.8 6.2 6.1 8.4 6.1 1.0 3.1 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger FAD_binding_7 PF03441.9 GAP92107.1 - 5.4e-53 179.9 0.0 8e-53 179.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 GAP92107.1 - 8.5e-20 71.1 0.0 1.4e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase 4HBT PF03061.17 GAP92108.1 - 3.3e-05 23.9 0.1 0.0001 22.3 0.0 1.9 2 0 0 2 2 2 1 Thioesterase superfamily Polysacc_deac_1 PF01522.16 GAP92109.1 - 1.5e-22 79.5 0.0 2.7e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 GAP92109.1 - 0.057 12.8 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) adh_short_C2 PF13561.1 GAP92110.1 - 5.2e-27 95.1 0.0 5.8e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAP92110.1 - 6.2e-27 94.5 6.6 9.5e-27 93.9 4.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP92110.1 - 1.2e-12 47.8 2.4 1.2e-12 47.8 1.7 1.5 2 0 0 2 2 2 1 KR domain SQS_PSY PF00494.14 GAP92111.1 - 3.4e-65 219.9 0.4 4.9e-65 219.4 0.3 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Amino_oxidase PF01593.19 GAP92112.1 - 2.6e-14 53.1 0.3 4.2e-14 52.4 0.2 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAP92112.1 - 9e-14 51.2 0.2 2.3e-13 49.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAP92112.1 - 8.1e-11 41.4 6.9 1.9e-09 36.9 4.8 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAP92112.1 - 5.2e-05 23.2 0.0 8.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAP92112.1 - 6.4e-05 21.6 0.3 0.00034 19.2 1.2 1.4 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 GAP92112.1 - 0.00013 20.9 3.7 0.0002 20.3 2.5 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 GAP92112.1 - 0.00021 21.3 0.1 0.00053 20.1 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAP92112.1 - 0.0014 17.7 3.8 0.0023 17.0 2.6 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAP92112.1 - 0.0015 17.6 0.1 0.0031 16.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 GAP92112.1 - 0.011 16.1 0.7 0.04 14.3 0.7 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAP92112.1 - 0.022 13.8 0.3 0.033 13.2 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 GAP92112.1 - 0.073 12.7 0.3 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 GAP92112.1 - 0.11 11.9 0.9 0.18 11.2 0.6 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 GAP92112.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 GAP92112.1 - 0.24 11.1 1.9 0.26 11.0 0.2 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 GAP92112.1 - 0.29 9.9 5.7 0.054 12.3 1.6 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 GAP92112.1 - 1.7 7.4 3.9 0.54 9.1 0.7 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Beta-lactamase PF00144.19 GAP92113.1 - 1.1e-22 80.5 2.5 1.1e-22 80.5 1.8 2.7 1 1 2 3 3 3 1 Beta-lactamase Pkinase PF00069.20 GAP92114.1 - 4.7e-44 150.4 0.0 6.8e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP92114.1 - 1.8e-23 82.9 0.0 3.3e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 GAP92114.1 - 0.00042 19.4 0.0 0.00078 18.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 GAP92114.1 - 0.011 14.7 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.12 GAP92115.1 - 0.0023 17.0 0.0 0.069 12.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 GAP92115.1 - 0.0059 15.7 0.0 0.038 13.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain DUF1628 PF07790.6 GAP92116.1 - 0.091 13.5 0.0 0.25 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1628) MAPEG PF01124.13 GAP92117.1 - 4.3e-17 61.9 2.2 6.1e-17 61.4 1.5 1.2 1 0 0 1 1 1 1 MAPEG family CAMSAP_CKK PF08683.6 GAP92117.1 - 0.16 11.6 0.0 0.22 11.2 0.0 1.1 1 0 0 1 1 1 0 Microtubule-binding calmodulin-regulated spectrin-associated BNR PF02012.15 GAP92118.1 - 4.9 7.4 6.2 0.69 9.9 0.2 2.9 3 0 0 3 3 3 0 BNR/Asp-box repeat Mito_fiss_Elm1 PF06258.6 GAP92119.1 - 0.027 13.4 0.0 0.029 13.3 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial fission ELM1 Glyco_hydro_67M PF07488.7 GAP92120.1 - 9.8e-145 481.5 0.0 1.3e-144 481.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.7 GAP92120.1 - 5.9e-94 313.6 2.1 9e-94 313.0 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.9 GAP92120.1 - 2.5e-29 101.7 0.0 3.9e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.10 GAP92120.1 - 0.002 18.6 0.1 0.0056 17.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 PPR_2 PF13041.1 GAP92121.1 - 0.033 14.1 0.0 2.8 7.9 0.0 2.6 2 0 0 2 2 2 0 PPR repeat family DUF155 PF02582.9 GAP92122.1 - 2.2e-34 118.9 0.0 2.9e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Prefoldin_3 PF13758.1 GAP92122.1 - 0.028 14.1 1.0 0.13 12.0 0.2 2.3 1 1 1 2 2 2 0 Prefoldin subunit Cupin_3 PF05899.7 GAP92122.1 - 0.067 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF1451 PF07295.6 GAP92122.1 - 0.087 12.5 0.0 0.38 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) BNR_2 PF13088.1 GAP92123.1 - 2.5e-09 36.8 0.1 0.0022 17.3 0.0 3.2 1 1 3 4 4 4 4 BNR repeat-like domain BNR PF02012.15 GAP92123.1 - 6.2e-06 25.2 12.2 2 8.5 0.1 5.4 5 0 0 5 5 5 4 BNR/Asp-box repeat SR-25 PF10500.4 GAP92123.1 - 0.00012 21.6 20.8 0.00017 21.1 2.2 2.3 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein Shisa PF13908.1 GAP92123.1 - 0.00015 21.9 4.8 0.0003 21.0 3.3 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Suf PF05843.9 GAP92123.1 - 0.1 12.3 7.3 0.15 11.8 5.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MIP-T3 PF10243.4 GAP92123.1 - 0.16 10.3 10.5 0.071 11.5 5.5 1.6 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Tim54 PF11711.3 GAP92123.1 - 4.8 5.6 6.4 7.2 5.0 4.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF605 PF04652.11 GAP92123.1 - 6.1 6.1 27.3 0.51 9.6 15.5 1.6 2 0 0 2 2 2 0 Vta1 like RR_TM4-6 PF06459.7 GAP92123.1 - 7.6 6.3 8.2 14 5.4 5.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Asp PF00026.18 GAP92124.1 - 1.7e-109 365.9 0.1 2e-109 365.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAP92124.1 - 3.8e-11 43.2 0.1 1.2e-10 41.5 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 GAP92124.1 - 1.3e-07 32.0 0.2 0.0065 16.9 0.0 3.2 2 2 1 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 GAP92124.1 - 6.2e-07 29.0 0.0 3.8e-06 26.5 0.0 2.2 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Alpha-amylase_C PF02806.13 GAP92124.1 - 0.1 12.7 0.0 2 8.5 0.0 2.4 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain SHMT PF00464.14 GAP92126.1 - 4.2e-207 687.2 0.0 4.9e-207 687.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.14 GAP92126.1 - 0.002 16.9 0.0 0.0029 16.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 GAP92126.1 - 0.011 14.9 0.0 0.047 12.8 0.0 2.0 1 1 0 1 1 1 0 Beta-eliminating lyase adh_short PF00106.20 GAP92127.1 - 3.5e-08 33.5 0.0 1.4e-07 31.5 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP92127.1 - 0.00096 18.8 0.0 0.0027 17.3 0.0 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 GAP92127.1 - 0.13 11.7 0.1 0.87 8.9 0.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Gln-synt_C PF00120.19 GAP92128.1 - 3.3e-27 95.2 0.0 4.6e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain UDPGT PF00201.13 GAP92129.1 - 3.8e-07 29.0 0.1 5.6e-07 28.4 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Aminotran_1_2 PF00155.16 GAP92130.1 - 7.4e-39 133.7 0.0 1e-38 133.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 GAP92130.1 - 1.3e-08 34.0 0.0 1.9e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 GAP92130.1 - 9.6e-07 28.2 0.0 1.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 GAP92130.1 - 1.4e-06 26.9 0.0 2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 GAP92130.1 - 1.5e-06 27.5 0.2 2.2e-06 26.9 0.2 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_MocR PF12897.2 GAP92130.1 - 2.1e-05 23.3 0.0 2.9e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Alliinase_C PF04864.8 GAP92130.1 - 0.0043 15.7 0.0 0.0069 15.0 0.0 1.3 1 0 0 1 1 1 1 Allinase Amidohydro_4 PF13147.1 GAP92130.1 - 0.0075 16.3 0.6 0.01 15.8 0.4 1.3 1 0 0 1 1 1 1 Amidohydrolase Pilus_CpaD PF09476.5 GAP92130.1 - 0.072 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) Flavodoxin_1 PF00258.20 GAP92131.1 - 2.6e-08 33.9 0.2 5.9e-08 32.8 0.1 1.7 1 1 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 GAP92131.1 - 3.8e-07 29.7 0.0 5.3e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 GAP92131.1 - 9.6e-06 25.2 0.0 1.2e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 GAP92131.1 - 0.023 14.6 0.0 0.24 11.3 0.0 2.1 1 1 1 2 2 2 0 Flavodoxin domain IncA PF04156.9 GAP92132.1 - 0.0019 17.8 0.0 0.0037 16.8 0.0 1.4 1 1 0 1 1 1 1 IncA protein CR6_interact PF10147.4 GAP92132.1 - 0.098 11.9 2.0 0.22 10.8 1.4 1.4 1 1 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 AAA PF00004.24 GAP92133.1 - 2.9e-18 66.3 0.0 5.8e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 GAP92133.1 - 0.00048 19.3 1.5 0.0014 17.7 0.5 1.9 1 1 1 2 2 2 1 KaiC AAA_16 PF13191.1 GAP92133.1 - 0.0022 18.0 0.3 0.026 14.5 0.1 2.6 3 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 GAP92133.1 - 0.0034 17.1 0.0 0.0095 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 GAP92133.1 - 0.0073 16.4 0.4 0.13 12.4 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 GAP92133.1 - 0.012 15.3 0.0 0.035 13.8 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Zot PF05707.7 GAP92133.1 - 0.021 14.2 0.1 0.82 9.1 0.0 2.4 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) AAA_30 PF13604.1 GAP92133.1 - 0.078 12.5 0.5 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 GAP92133.1 - 0.11 11.6 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin HET PF06985.6 GAP92134.1 - 1.6e-18 67.1 0.2 3.2e-18 66.2 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ribosomal_S8 PF00410.14 GAP92136.1 - 8.8e-22 77.3 0.0 1.2e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Iso_dh PF00180.15 GAP92138.1 - 3e-93 312.5 0.0 6.1e-93 311.5 0.0 1.4 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase GTP_EFTU PF00009.22 GAP92139.1 - 9.1e-57 191.5 0.4 1.9e-56 190.4 0.3 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 GAP92139.1 - 8.8e-32 108.7 0.0 1.9e-31 107.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 GAP92139.1 - 2.6e-31 107.6 0.0 5.5e-31 106.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 GAP92139.1 - 1.4e-22 79.3 0.0 3.4e-22 78.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 GAP92139.1 - 2.2e-13 50.0 0.0 5.6e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Asp PF00026.18 GAP92140.1 - 7e-65 219.3 1.5 8.4e-65 219.0 1.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAP92140.1 - 4.1e-06 26.8 0.5 4e-05 23.6 0.2 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 GAP92140.1 - 0.0038 16.7 0.0 0.027 14.0 0.0 2.3 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 GAP92140.1 - 0.016 15.0 0.0 3.9 7.3 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 GAP92140.1 - 0.053 14.0 0.1 25 5.4 0.0 3.1 2 1 0 2 2 2 0 Aspartyl protease Peptidase_M14 PF00246.19 GAP92141.1 - 2.7e-67 227.3 0.0 3.6e-67 226.9 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 GAP92141.1 - 0.022 14.4 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 Carboxypeptidase activation peptide G_glu_transpept PF01019.16 GAP92142.1 - 1.2e-161 538.7 0.1 1.5e-161 538.4 0.1 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase NAD_binding_10 PF13460.1 GAP92142.1 - 2.1e-13 50.6 0.1 5.9e-13 49.2 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding Fungal_trans PF04082.13 GAP92143.1 - 3.9e-21 75.0 0.0 6.8e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldedh PF00171.17 GAP92144.1 - 1.3e-162 541.3 0.0 1.5e-162 541.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Kelch_5 PF13854.1 GAP92145.1 - 1e-11 44.5 8.3 4.9e-11 42.3 0.2 3.9 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.10 GAP92145.1 - 5e-07 29.2 8.0 0.47 10.3 0.3 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.1 GAP92145.1 - 9.4e-07 28.8 1.3 0.023 14.8 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 GAP92145.1 - 0.00029 20.3 2.6 2 8.0 0.1 4.2 4 0 0 4 4 4 2 Kelch motif EphA2_TM PF14575.1 GAP92145.1 - 0.0012 19.2 1.6 0.005 17.1 0.0 2.6 3 0 0 3 3 3 1 Ephrin type-A receptor 2 transmembrane domain DUF1191 PF06697.7 GAP92145.1 - 0.0073 15.1 0.0 0.015 14.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Legionella_OMP PF05150.7 GAP92145.1 - 0.019 14.1 0.3 0.029 13.4 0.2 1.2 1 0 0 1 1 1 0 Legionella pneumophila major outer membrane protein precursor Protocadherin PF08374.6 GAP92145.1 - 0.028 14.0 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Protocadherin Syndecan PF01034.15 GAP92145.1 - 0.24 11.0 0.3 0.52 10.0 0.2 1.5 1 0 0 1 1 1 0 Syndecan domain Kelch_6 PF13964.1 GAP92145.1 - 0.82 9.9 14.5 6.9 7.0 0.4 5.0 3 2 1 4 4 4 0 Kelch motif Nitr_red_bet_C PF14711.1 GAP92146.1 - 9.5e-08 31.4 0.0 2 7.9 0.0 5.1 3 1 2 5 5 5 2 Respiratory nitrate reductase beta C-terminal GP46 PF07409.7 GAP92146.1 - 1.2e-05 24.5 1.7 15 4.9 0.0 5.1 4 1 1 5 5 5 1 Phage protein GP46 DUF433 PF04255.9 GAP92146.1 - 0.00025 20.4 0.6 58 3.2 0.0 5.3 5 0 0 5 5 5 0 Protein of unknown function (DUF433) TFIIE_alpha PF02002.12 GAP92146.1 - 0.0005 19.5 0.3 69 3.0 0.0 4.9 4 1 1 5 5 5 0 TFIIE alpha subunit Symplekin_C PF12295.3 GAP92146.1 - 0.007 16.2 0.0 0.21 11.4 0.0 2.3 1 1 0 2 2 2 1 Symplekin tight junction protein C terminal ArsD PF06953.6 GAP92146.1 - 0.03 14.4 0.6 54 3.9 0.0 3.6 1 1 3 4 4 4 0 Arsenical resistance operon trans-acting repressor ArsD SUKH_6 PF14568.1 GAP92146.1 - 0.086 13.3 0.2 49 4.4 0.0 3.1 1 1 2 3 3 3 0 SMI1-KNR4 cell-wall DUF3328 PF11807.3 GAP92147.1 - 2e-49 168.2 0.4 2.5e-49 167.8 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Med25_NR-box PF11244.3 GAP92149.1 - 0.36 11.3 9.3 1.9 8.9 2.2 2.1 2 0 0 2 2 2 0 Mediator complex subunit 25 C-terminal NR box-containing GFO_IDH_MocA PF01408.17 GAP92150.1 - 5.4e-24 85.0 0.1 8.3e-24 84.4 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 GAP92150.1 - 5.5e-13 48.7 0.0 1.4e-12 47.4 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DapB_N PF01113.15 GAP92150.1 - 0.00056 19.8 0.2 0.0045 16.8 0.0 2.3 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 GAP92150.1 - 0.0011 19.2 0.1 0.0025 18.1 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_N PF00044.19 GAP92150.1 - 0.0022 17.9 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain CoA_binding PF02629.14 GAP92150.1 - 0.073 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain DUF4291 PF14124.1 GAP92151.1 - 5.8e-64 215.0 1.7 6.9e-64 214.7 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) CFEM PF05730.6 GAP92153.1 - 0.0016 18.2 2.8 0.0038 17.0 1.9 1.6 1 1 0 1 1 1 1 CFEM domain Leukemia_assc_2 PF15197.1 GAP92153.1 - 0.65 9.7 2.0 0.67 9.6 0.2 1.8 2 0 0 2 2 2 0 Leukemia-associated protein 2 SBP_bac_6 PF13343.1 GAP92155.1 - 5.9e-16 58.5 0.0 1.1e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.1 GAP92155.1 - 2.2e-09 37.3 0.0 3.3e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.20 GAP92155.1 - 0.0022 17.7 1.6 0.008 15.9 1.1 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein F-box-like PF12937.2 GAP92156.1 - 5.9e-06 25.9 0.1 1.6e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like GspL_C PF12693.2 GAP92156.1 - 0.0089 15.8 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 1 GspL periplasmic domain ATPase_gene1 PF09527.5 GAP92157.1 - 1.9 8.3 5.9 0.32 10.8 0.7 2.1 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) DUF1857 PF08982.6 GAP92159.1 - 1.3e-43 148.1 0.0 1.4e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Noc2 PF03715.8 GAP92160.1 - 2.8e-120 400.7 0.0 4.6e-120 399.9 0.0 1.4 1 0 0 1 1 1 1 Noc2p family VPS28 PF03997.7 GAP92161.1 - 1.2e-51 175.0 0.2 1.4e-51 174.8 0.2 1.0 1 0 0 1 1 1 1 VPS28 protein tRNA-synt_2c PF01411.14 GAP92162.1 - 3.4e-09 35.5 0.2 5e-09 34.9 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 GAP92162.1 - 6.3e-07 29.1 0.3 1.3e-06 28.2 0.2 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF3419 PF11899.3 GAP92163.1 - 9.4e-158 524.8 0.0 1.6e-157 524.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 GAP92163.1 - 2.3e-14 53.4 0.0 3.5e-13 49.5 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP92163.1 - 9.3e-09 35.8 0.0 8.3e-08 32.7 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP92163.1 - 1.6e-06 28.1 0.2 0.00013 21.9 0.0 3.3 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP92163.1 - 2.1e-06 27.3 0.0 3.6e-05 23.3 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP92163.1 - 3.3e-06 27.4 0.0 2.7e-05 24.5 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP92163.1 - 0.00018 20.6 0.0 0.035 13.2 0.0 2.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 GAP92163.1 - 0.0003 21.0 0.0 0.00075 19.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP92163.1 - 0.00068 20.0 0.0 0.015 15.7 0.0 3.0 4 0 0 4 4 4 1 Methyltransferase domain PCMT PF01135.14 GAP92163.1 - 0.00079 19.0 0.0 0.002 17.7 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Glyco_hydro_28 PF00295.12 GAP92164.1 - 9.3e-34 116.8 6.4 1.5e-33 116.1 4.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 BTB PF00651.26 GAP92165.1 - 0.025 14.5 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain RNase_P_p30 PF01876.11 GAP92167.1 - 1.2e-41 141.4 0.0 2.2e-41 140.6 0.0 1.4 1 0 0 1 1 1 1 RNase P subunit p30 Peptidase_M50B PF13398.1 GAP92169.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like CobT PF06213.7 GAP92170.1 - 0.073 12.2 12.4 0.099 11.7 8.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Neur_chan_memb PF02932.11 GAP92170.1 - 0.09 12.6 12.1 0.12 12.2 8.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.10 GAP92170.1 - 0.094 11.3 7.8 0.1 11.2 5.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Asp-B-Hydro_N PF05279.6 GAP92170.1 - 0.37 10.5 20.6 0.45 10.3 14.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region MIP-T3 PF10243.4 GAP92170.1 - 0.52 8.7 37.0 0.7 8.2 25.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 MDFI PF15316.1 GAP92170.1 - 1.4 8.8 7.0 2 8.4 4.8 1.3 1 0 0 1 1 1 0 MyoD family inhibitor Hid1 PF12722.2 GAP92170.1 - 1.7 6.2 10.1 1.9 6.0 7.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein eIF_4EBP PF05456.6 GAP92170.1 - 2.7 7.7 9.7 0.37 10.5 0.8 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) CT47 PF15623.1 GAP92170.1 - 3.6 7.2 23.3 5 6.7 16.1 1.3 1 0 0 1 1 1 0 Cancer/testis gene family 47 Presenilin PF01080.12 GAP92170.1 - 3.7 6.2 9.6 4.5 5.9 6.7 1.1 1 0 0 1 1 1 0 Presenilin SRP-alpha_N PF04086.8 GAP92170.1 - 5.5 6.2 25.4 6.8 5.9 17.6 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF4407 PF14362.1 GAP92170.1 - 5.6 5.8 13.5 6.6 5.5 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.11 GAP92170.1 - 6.2 5.2 7.1 6.8 5.1 5.0 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1510 PF07423.6 GAP92170.1 - 8.4 5.6 30.4 12 5.1 21.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Paramyxo_ncap PF00973.14 GAP92170.1 - 9.7 4.7 7.3 12 4.4 5.0 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Pkinase PF00069.20 GAP92171.1 - 9.8e-63 211.7 0.0 1.3e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP92171.1 - 1.7e-28 99.4 0.0 2.5e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP92171.1 - 7.6e-08 31.6 0.0 1e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAP92171.1 - 0.011 14.7 0.0 0.028 13.4 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAP92171.1 - 0.046 13.4 0.0 1 9.0 0.0 2.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family UQ_con PF00179.21 GAP92172.1 - 2.3e-49 166.4 0.0 2.9e-49 166.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAP92172.1 - 2.7e-06 27.1 0.0 3.5e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 GAP92172.1 - 0.0013 18.5 0.1 0.0019 18.0 0.1 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 GAP92172.1 - 0.0024 17.5 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 UEV domain Ribosomal_L31e PF01198.14 GAP92173.1 - 2e-37 126.7 2.4 3.2e-37 126.0 1.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L31e RGS PF00615.14 GAP92174.1 - 1.5e-12 47.6 0.0 2.2e-09 37.4 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain PCI PF01399.22 GAP92175.1 - 7.3e-08 32.6 0.0 1.3e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 PCI domain E1-E2_ATPase PF00122.15 GAP92176.1 - 5.5e-54 182.6 0.6 1.2e-53 181.5 0.4 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 GAP92176.1 - 2.8e-49 168.4 4.3 4.3e-49 167.8 1.4 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 GAP92176.1 - 2.6e-40 136.3 0.1 1.8e-09 37.5 0.0 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 GAP92176.1 - 1.2e-14 54.8 0.0 3.2e-14 53.5 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAP92176.1 - 7.4e-07 28.9 0.8 0.00017 21.2 0.2 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF1656 PF07869.7 GAP92176.1 - 0.0069 16.1 1.0 0.0069 16.1 0.7 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1656) DUF4038 PF13204.1 GAP92176.1 - 0.27 10.5 0.0 0.46 9.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) Amidase PF01425.16 GAP92178.1 - 1.3e-37 129.6 2.7 3.3e-36 125.0 0.7 2.2 2 0 0 2 2 2 2 Amidase SLH PF00395.15 GAP92179.1 - 0.078 12.7 0.1 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 S-layer homology domain PAT1 PF09770.4 GAP92179.1 - 3.2 5.8 9.9 4 5.5 6.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pkinase PF00069.20 GAP92180.1 - 7.8e-15 54.7 0.0 1.1e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP92180.1 - 7.3e-08 31.7 0.0 1.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 GAP92180.1 - 0.079 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.11 GAP92182.1 - 1.2e-37 129.4 39.4 3.1e-37 128.1 23.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAP92182.1 - 4.4e-07 28.4 0.8 8.3e-07 27.5 0.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 GAP92182.1 - 8.4e-06 24.1 1.3 1.2e-05 23.7 0.9 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector DUF4212 PF13937.1 GAP92182.1 - 0.76 9.8 6.1 0.75 9.8 1.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) DUF2263 PF10021.4 GAP92183.1 - 8.9e-25 87.4 0.0 1.4e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Mg_chelatase PF01078.16 GAP92183.1 - 0.15 11.2 0.0 0.33 10.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI EPSP_synthase PF00275.15 GAP92184.1 - 6e-128 426.8 0.0 8.7e-128 426.3 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 GAP92184.1 - 2.3e-99 331.5 0.0 3.7e-99 330.8 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 GAP92184.1 - 4.8e-62 209.5 0.0 7.4e-62 208.9 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 GAP92184.1 - 9.2e-38 129.5 0.0 5.2e-36 123.8 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 GAP92184.1 - 8.4e-24 83.4 0.0 2e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 GAP92184.1 - 4.2e-10 39.8 0.0 1e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 GAP92184.1 - 2.7e-07 30.1 0.0 1.6e-06 27.6 0.0 2.0 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 GAP92184.1 - 0.013 16.3 0.0 0.088 13.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain zf-C2H2 PF00096.21 GAP92185.1 - 3.4e-08 33.3 12.5 0.015 15.5 1.1 4.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP92185.1 - 8.5e-05 22.6 19.6 0.0047 17.1 1.3 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger BAF1_ABF1 PF04684.8 GAP92185.1 - 3 6.5 12.6 6 5.6 8.7 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF1180 PF06679.7 GAP92185.1 - 7.8 6.3 6.7 11 5.9 1.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Histone PF00125.19 GAP92186.1 - 1.8e-15 56.7 0.1 2.2e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 GAP92186.1 - 0.00012 21.9 0.1 0.00017 21.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 GAP92186.1 - 0.00012 22.1 0.1 0.00017 21.7 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 GAP92186.1 - 0.00033 20.6 0.1 0.00059 19.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 GAP92186.1 - 0.013 15.2 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 GAP92186.1 - 0.022 14.0 0.0 0.022 14.0 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 GAP92187.1 - 3.6e-31 107.0 0.4 5.8e-31 106.4 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 GAP92187.1 - 4.1e-06 26.8 0.0 6.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 GAP92187.1 - 0.004 17.1 0.3 0.0074 16.3 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 GAP92187.1 - 0.014 15.1 0.1 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated RNA_pol_Rpb1_5 PF04998.12 GAP92188.1 - 1.5e-87 293.4 0.1 9.7e-87 290.7 0.0 2.4 2 2 1 3 3 3 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 GAP92188.1 - 8.7e-64 214.4 0.1 3.2e-63 212.6 0.1 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 GAP92188.1 - 1.3e-32 112.6 0.0 1.1e-31 109.6 0.0 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 GAP92188.1 - 1.2e-29 103.7 9.3 1.7e-21 76.8 0.0 3.3 2 1 1 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 GAP92188.1 - 3.4e-15 55.7 0.5 2e-14 53.2 0.0 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 HET PF06985.6 GAP92189.1 - 3.8e-25 88.6 0.0 8.5e-25 87.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PRP3 PF08572.5 GAP92190.1 - 3.8e-69 232.4 4.1 6.7e-69 231.6 2.9 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 GAP92190.1 - 6.8e-36 122.7 0.5 1.4e-35 121.7 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) DUF1227 PF06777.6 GAP92191.1 - 2.8e-61 205.4 0.5 7.8e-61 204.0 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 GAP92191.1 - 7.2e-52 175.3 0.4 1.3e-51 174.4 0.3 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 GAP92191.1 - 4.3e-44 150.4 0.0 1.4e-43 148.7 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain SNF2_N PF00176.18 GAP92191.1 - 4.9e-05 22.2 0.0 0.00025 19.9 0.0 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 GAP92191.1 - 0.0014 18.1 0.0 0.51 9.8 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 GAP92191.1 - 0.011 15.5 0.0 0.059 13.2 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 GAP92191.1 - 0.015 14.9 0.2 0.059 12.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAP92191.1 - 0.04 14.0 0.1 3.1 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 GAP92191.1 - 0.11 11.7 0.0 6.3 5.9 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein OmpH PF03938.9 GAP92191.1 - 0.16 11.8 4.4 0.55 10.1 0.0 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF2951 PF11166.3 GAP92192.1 - 0.31 10.9 4.4 1 9.2 3.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) DDHD PF02862.12 GAP92194.1 - 6.5e-37 127.5 0.3 5.7e-20 72.0 0.0 3.0 3 1 0 4 4 4 2 DDHD domain Abhydrolase_6 PF12697.2 GAP92194.1 - 0.002 18.0 0.6 0.0048 16.8 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP92194.1 - 0.0041 16.7 0.0 0.0081 15.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP92194.1 - 0.0095 15.7 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 GAP92194.1 - 0.058 12.8 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DSPc PF00782.15 GAP92195.1 - 7.8e-28 96.7 0.0 1e-22 80.1 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAP92195.1 - 8.6e-05 21.9 0.0 0.00057 19.2 0.0 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 GAP92195.1 - 0.12 12.4 0.1 0.39 10.7 0.1 1.7 2 0 0 2 2 2 0 Inositol hexakisphosphate WD40 PF00400.27 GAP92196.1 - 9.1e-06 25.3 5.9 0.00039 20.2 0.0 3.9 5 0 0 5 5 5 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 GAP92196.1 - 0.0033 16.2 0.0 0.083 11.6 0.0 2.2 2 0 0 2 2 2 1 Coatomer WD associated region CNH PF00780.17 GAP92196.1 - 0.0066 15.9 0.0 2.2 7.6 0.0 3.3 3 1 0 3 3 3 1 CNH domain Hira PF07569.6 GAP92196.1 - 0.088 12.0 0.0 0.24 10.6 0.0 1.7 1 0 0 1 1 1 0 TUP1-like enhancer of split Apc4_WD40 PF12894.2 GAP92196.1 - 0.12 11.9 0.0 15 5.1 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Cupin_8 PF13621.1 GAP92197.1 - 4.7e-38 131.1 0.0 6.8e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.9 GAP92197.1 - 7.9e-20 71.1 0.0 1.3e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 GAP92197.1 - 1.5e-09 37.4 6.7 0.00018 21.2 0.1 4.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.1 GAP92197.1 - 7e-06 26.0 5.2 0.34 11.1 0.0 4.6 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.20 GAP92197.1 - 0.00049 19.5 0.0 0.54 9.8 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Cupin_4 PF08007.7 GAP92197.1 - 0.0029 16.9 0.0 0.0047 16.2 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Transket_pyr PF02779.19 GAP92198.1 - 5.2e-65 218.2 0.0 8.8e-65 217.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 GAP92198.1 - 1.6e-54 184.6 0.0 2.5e-54 184.0 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component TFIIH_BTF_p62_N PF08567.6 GAP92199.1 - 1.5e-23 82.2 0.0 3.2e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.12 GAP92199.1 - 7.5e-21 73.6 1.5 6.1e-13 48.3 0.2 3.1 2 0 0 2 2 2 2 BSD domain CysG_dimeriser PF10414.4 GAP92199.1 - 0.092 12.2 0.4 7.3 6.1 0.0 2.8 2 0 0 2 2 2 0 Sirohaem synthase dimerisation region DUF3439 PF11921.3 GAP92200.1 - 0.056 13.1 0.8 0.12 12.0 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) CENP-B_dimeris PF09026.5 GAP92200.1 - 0.073 13.3 6.2 0.17 12.1 4.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4611 PF15387.1 GAP92200.1 - 0.092 12.9 2.4 0.18 11.9 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 GAP92200.1 - 0.1 12.1 3.5 0.17 11.3 2.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 GAP92200.1 - 0.17 12.1 5.7 0.44 10.8 4.0 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.6 GAP92200.1 - 3.2 7.5 6.7 0.85 9.4 2.5 1.6 2 0 0 2 2 2 0 RXT2-like, N-terminal Sporozoite_P67 PF05642.6 GAP92200.1 - 7.1 4.3 10.2 0.11 10.3 1.6 1.7 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Mucin PF01456.12 GAP92200.1 - 8.1 6.2 10.1 0.89 9.3 0.7 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein WD40 PF00400.27 GAP92202.1 - 1.3e-45 151.7 19.6 3e-12 45.9 0.3 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Apc4_WD40 PF12894.2 GAP92202.1 - 0.013 15.0 0.0 30 4.2 0.0 4.6 6 0 0 6 6 6 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4613 PF15390.1 GAP92202.1 - 0.25 9.4 0.4 1.8 6.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4613) DAO PF01266.19 GAP92203.1 - 2.5e-50 171.4 0.0 3.5e-50 170.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 GAP92203.1 - 3.3e-07 29.7 3.1 5.2e-06 25.8 2.2 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAP92203.1 - 1.7e-06 27.1 0.4 5.5e-06 25.4 0.2 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 GAP92203.1 - 0.00022 21.1 0.0 0.00047 20.1 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAP92203.1 - 0.0027 16.8 0.1 0.051 12.6 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.13 GAP92203.1 - 0.01 15.5 0.3 0.019 14.5 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 GAP92203.1 - 0.019 13.8 0.0 0.61 8.9 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 GAP92203.1 - 0.021 13.9 0.2 0.44 9.6 0.1 2.2 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.1 GAP92203.1 - 0.022 14.7 0.1 0.078 13.0 0.1 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 GAP92203.1 - 0.026 13.3 0.1 0.071 11.9 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 GAP92203.1 - 0.027 12.9 0.3 0.042 12.3 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 GAP92203.1 - 0.027 14.8 0.7 0.1 13.0 0.4 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP92203.1 - 0.084 12.9 0.0 0.22 11.5 0.0 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3115 PF11312.3 GAP92203.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) K_oxygenase PF13434.1 GAP92203.1 - 0.2 10.5 0.1 0.52 9.1 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) RGS PF00615.14 GAP92204.1 - 1.6e-08 34.6 0.0 2.6e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain CytoC_RC PF02276.13 GAP92206.1 - 0.076 12.1 1.1 0.093 11.8 0.8 1.1 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit DUF3337 PF11816.3 GAP92207.1 - 2.5e-96 322.9 0.0 7.7e-92 308.2 0.6 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 GAP92207.1 - 5.3e-27 92.6 14.3 6.7e-06 25.7 0.0 6.8 6 1 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 GAP92207.1 - 0.017 13.3 2.7 0.076 11.1 0.0 2.5 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Mito_carr PF00153.22 GAP92208.1 - 9.2e-48 159.9 7.7 3.8e-18 64.9 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF3482 PF11981.3 GAP92208.1 - 0.69 9.0 4.2 0.18 10.9 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) ATP_bind_3 PF01171.15 GAP92209.1 - 6.3e-41 139.8 0.0 1.2e-29 103.1 0.0 2.2 2 0 0 2 2 2 2 PP-loop family Asn_synthase PF00733.16 GAP92209.1 - 0.00099 18.6 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 Asparagine synthase Hist_deacetyl PF00850.14 GAP92211.1 - 1e-91 307.4 0.0 1.5e-91 306.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 GAP92211.1 - 8.7e-38 129.5 0.0 1.3e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain F-box-like PF12937.2 GAP92212.1 - 0.037 13.7 0.0 0.44 10.2 0.0 2.4 2 0 0 2 2 2 0 F-box-like Brix PF04427.13 GAP92213.1 - 6.4e-38 130.3 0.0 8.7e-38 129.8 0.0 1.2 1 0 0 1 1 1 1 Brix domain Str_synth PF03088.11 GAP92213.1 - 0.023 14.7 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 Strictosidine synthase Menin PF05053.8 GAP92213.1 - 0.051 11.7 0.3 0.069 11.3 0.2 1.1 1 0 0 1 1 1 0 Menin p450 PF00067.17 GAP92215.1 - 1.8e-44 152.0 0.0 1.6e-25 89.5 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF1870 PF08965.5 GAP92215.1 - 0.098 12.3 0.4 1.4 8.5 0.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF1870) MFS_1 PF07690.11 GAP92216.1 - 3.1e-27 95.2 48.2 7.5e-17 61.0 19.2 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP92216.1 - 1.4e-08 33.7 28.2 6.7e-07 28.2 7.3 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 GAP92216.1 - 6.7e-08 31.1 10.3 9.4e-07 27.3 7.1 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) 4HBT_3 PF13622.1 GAP92217.1 - 1e-24 87.6 4.8 1e-24 87.6 3.3 1.5 2 0 0 2 2 2 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 GAP92217.1 - 9.3e-12 44.7 0.0 2.4e-08 33.6 0.0 2.4 2 0 0 2 2 2 2 Acyl-CoA thioesterase ADH_zinc_N PF00107.21 GAP92217.1 - 1.3e-07 31.1 0.0 2.6e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP92217.1 - 6.4e-05 22.6 0.0 0.00015 21.4 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AMP-binding PF00501.23 GAP92219.1 - 7.7e-78 261.7 0.0 1.2e-77 261.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 GAP92219.1 - 7.5e-70 235.2 0.0 1.9e-69 233.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 GAP92219.1 - 4e-53 179.7 0.4 2.5e-51 173.9 0.0 3.0 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.16 GAP92219.1 - 5.2e-47 160.7 0.0 1.3e-46 159.4 0.0 1.6 2 0 0 2 2 1 1 Acyl transferase domain Condensation PF00668.15 GAP92219.1 - 2.4e-46 157.9 0.2 3.5e-46 157.4 0.1 1.2 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 GAP92219.1 - 2.9e-45 154.1 0.3 6.3e-42 143.3 0.0 3.0 3 0 0 3 3 2 2 short chain dehydrogenase PS-DH PF14765.1 GAP92219.1 - 3.7e-36 124.8 0.0 7.4e-36 123.8 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 GAP92219.1 - 1e-32 112.4 0.0 3.9e-32 110.6 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 GAP92219.1 - 1.1e-31 109.6 0.0 5.2e-31 107.4 0.0 2.2 2 1 0 2 2 2 1 Male sterility protein PP-binding PF00550.20 GAP92219.1 - 1.3e-16 60.6 0.7 1.2e-07 31.9 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 GAP92219.1 - 9e-16 58.1 0.0 2.8e-15 56.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP92219.1 - 1.9e-13 50.4 0.0 4.8e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP92219.1 - 1.2e-10 41.7 0.0 4.6e-10 39.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain AMP-binding_C PF13193.1 GAP92219.1 - 3.6e-08 34.2 0.0 2.4e-07 31.5 0.0 2.6 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 GAP92219.1 - 2.1e-07 30.6 0.0 6.6e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_18 PF12847.2 GAP92219.1 - 3e-07 31.0 0.1 3.8e-06 27.4 0.0 3.1 4 0 0 4 4 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 GAP92219.1 - 5.2e-07 29.8 0.0 1.5e-06 28.3 0.0 1.9 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_31 PF13847.1 GAP92219.1 - 3.8e-06 26.5 0.0 1.4e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP92219.1 - 5.4e-06 25.6 0.0 1.1e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 GAP92219.1 - 3.8e-05 22.8 0.0 7.1e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.14 GAP92219.1 - 4.3e-05 22.3 0.0 0.0011 17.6 0.0 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_16 PF10294.4 GAP92219.1 - 0.0042 16.5 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase RmlD_sub_bind PF04321.12 GAP92219.1 - 0.057 12.2 0.0 0.21 10.4 0.0 2.0 1 1 0 1 1 1 0 RmlD substrate binding domain MHC2-interact PF09307.5 GAP92219.1 - 0.067 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 CLIP, MHC2 interacting CBFB_NFYA PF02045.10 GAP92219.1 - 0.6 10.6 0.5 1.3 9.6 0.3 1.5 1 0 0 1 1 1 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B LRR_4 PF12799.2 GAP92221.1 - 3.8e-33 112.5 47.5 6.1e-06 25.7 0.3 10.5 8 2 1 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAP92221.1 - 2.5e-21 75.1 45.8 1.2e-05 24.9 3.2 9.2 5 2 5 11 11 11 9 Leucine rich repeat LRR_1 PF00560.28 GAP92221.1 - 9.2e-11 40.2 49.9 0.043 13.8 0.1 15.9 17 2 1 18 18 18 3 Leucine Rich Repeat LRR_7 PF13504.1 GAP92221.1 - 2.2e-05 23.9 42.7 3.4 8.2 0.2 12.8 14 0 0 14 14 14 5 Leucine rich repeat LRR_6 PF13516.1 GAP92221.1 - 0.00068 19.4 37.1 1.7 8.9 0.1 10.1 10 0 0 10 10 10 3 Leucine Rich repeat LRR_9 PF14580.1 GAP92221.1 - 2.2 7.8 7.6 4.3 6.8 0.2 3.9 2 1 2 4 4 4 0 Leucine-rich repeat Meleagrin PF08189.6 GAP92222.1 - 0.0011 18.3 2.3 0.0021 17.4 1.6 1.5 1 0 0 1 1 1 1 Meleagrin/Cygnin family DUF3552 PF12072.3 GAP92223.1 - 0.064 12.4 13.5 0.11 11.6 9.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) IncA PF04156.9 GAP92223.1 - 0.21 11.1 9.7 0.42 10.1 6.7 1.5 1 0 0 1 1 1 0 IncA protein Mnd1 PF03962.10 GAP92223.1 - 0.76 9.4 7.3 1.9 8.1 5.1 1.6 1 0 0 1 1 1 0 Mnd1 family DUF4407 PF14362.1 GAP92223.1 - 2.4 7.0 6.2 13 4.6 4.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Thiolase_N PF00108.18 GAP92224.1 - 7.2e-70 234.9 3.4 1e-69 234.4 2.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAP92224.1 - 2.1e-40 136.9 1.9 2.6e-40 136.6 0.3 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain Dynamin_N PF00350.18 GAP92225.1 - 1.1e-33 116.4 0.0 2e-33 115.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 GAP92225.1 - 1.1e-16 60.4 0.6 1.3e-15 57.0 0.1 2.3 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 GAP92225.1 - 0.00014 21.8 0.0 0.00071 19.5 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.1 GAP92225.1 - 0.026 14.5 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 GAP92225.1 - 0.034 14.6 0.1 0.12 12.9 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein GED PF02212.13 GAP92225.1 - 0.1 12.4 1.9 0.36 10.7 0.1 2.9 3 1 0 3 3 3 0 Dynamin GTPase effector domain Fungal_trans PF04082.13 GAP92226.1 - 4.5e-21 74.8 0.0 8.3e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PRK PF00485.13 GAP92227.1 - 4.4e-06 26.3 0.0 0.0024 17.4 0.0 2.1 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 GAP92227.1 - 1.9e-05 25.4 0.1 8e-05 23.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAP92227.1 - 1.9e-05 24.5 0.0 4.5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 GAP92227.1 - 0.00017 20.7 0.1 0.00048 19.2 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.7 GAP92227.1 - 0.00085 19.0 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 GAP92227.1 - 0.0014 18.9 0.0 0.005 17.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain KTI12 PF08433.5 GAP92227.1 - 0.012 14.8 0.0 0.047 12.8 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_16 PF13191.1 GAP92227.1 - 0.016 15.1 0.4 0.043 13.8 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 GAP92227.1 - 0.032 13.9 0.0 0.099 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 GAP92227.1 - 0.045 13.1 0.0 0.28 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 GAP92227.1 - 0.056 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.17 GAP92227.1 - 0.078 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_31 PF13614.1 GAP92227.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Iso_dh PF00180.15 GAP92228.1 - 1.1e-87 294.2 0.0 1.3e-87 294.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Zn_clus PF00172.13 GAP92229.1 - 4.6e-08 32.8 10.4 6.7e-08 32.3 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF566 PF04484.7 GAP92229.1 - 5.7 6.3 6.3 8.3 5.8 4.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Sugar_tr PF00083.19 GAP92230.1 - 2.4e-90 303.2 25.4 3e-90 302.9 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP92230.1 - 8.5e-23 80.6 25.0 8.5e-23 80.6 17.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Phage_holin_2 PF04550.7 GAP92230.1 - 0.37 10.9 2.8 0.72 9.9 1.0 2.3 2 1 0 2 2 2 0 Phage holin family 2 Gp_dh_C PF02800.15 GAP92231.1 - 6e-55 184.9 0.1 9.2e-55 184.3 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 GAP92231.1 - 1.7e-38 131.9 0.0 3.7e-38 130.8 0.0 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Zn_clus PF00172.13 GAP92232.1 - 0.009 15.9 8.9 0.017 15.0 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pribosyltran PF00156.22 GAP92233.1 - 1.7e-07 31.0 0.2 2.1e-06 27.4 0.1 2.2 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Oxidored-like PF09791.4 GAP92234.1 - 6.1e-24 83.1 5.9 8.9e-24 82.6 2.6 2.5 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal DUF605 PF04652.11 GAP92234.1 - 0.34 10.2 21.1 0.44 9.8 14.6 1.3 1 0 0 1 1 1 0 Vta1 like Hamartin PF04388.7 GAP92234.1 - 7.5 5.0 11.6 9 4.8 8.0 1.3 1 0 0 1 1 1 0 Hamartin protein UBA_3 PF09288.5 GAP92235.1 - 0.0026 17.3 0.1 0.0061 16.1 0.0 1.6 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain FtsX PF02687.16 GAP92236.1 - 0.052 13.3 0.5 0.088 12.5 0.3 1.3 1 0 0 1 1 1 0 FtsX-like permease family CorA PF01544.13 GAP92236.1 - 0.088 11.8 2.1 0.06 12.3 0.2 1.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein NmrA PF05368.8 GAP92239.1 - 1.9e-29 102.5 0.0 3.9e-29 101.5 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAP92239.1 - 2.9e-14 53.4 0.7 5e-12 46.1 0.5 2.3 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAP92239.1 - 5.6e-05 22.6 0.1 0.0011 18.5 0.0 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Acetyltransf_8 PF13523.1 GAP92240.1 - 9.4e-33 113.2 0.1 1.3e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF607 PF04678.8 GAP92241.1 - 6.2e-38 130.5 0.1 1.8e-37 128.9 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF607 Ank_2 PF12796.2 GAP92242.1 - 1.8e-48 162.8 18.8 5e-19 68.4 1.6 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ras PF00071.17 GAP92242.1 - 5e-41 139.7 0.0 7.5e-41 139.2 0.0 1.3 1 0 0 1 1 1 1 Ras family Ank PF00023.25 GAP92242.1 - 1.5e-33 112.9 19.3 1.6e-05 24.4 0.1 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.1 GAP92242.1 - 1.3e-24 83.7 10.6 0.0011 19.0 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 GAP92242.1 - 1.7e-22 78.8 13.2 3.8e-08 33.3 0.0 6.2 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAP92242.1 - 1.8e-22 79.2 7.2 5.8e-06 26.6 0.2 5.0 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Miro PF08477.8 GAP92242.1 - 5.4e-12 46.2 0.0 9.8e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein DUF676 PF05057.9 GAP92242.1 - 6e-06 25.7 0.0 0.00083 18.6 0.0 2.4 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Arf PF00025.16 GAP92242.1 - 2.6e-05 23.5 0.0 4.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PGAP1 PF07819.8 GAP92242.1 - 0.0081 15.7 0.1 0.019 14.5 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein DUF1843 PF08898.5 GAP92242.1 - 2.1 8.4 8.6 34 4.5 0.2 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) Snf7 PF03357.16 GAP92243.1 - 2e-38 131.4 1.2 2.3e-38 131.2 0.8 1.0 1 0 0 1 1 1 1 Snf7 DUF848 PF05852.6 GAP92243.1 - 0.0035 17.1 2.0 0.011 15.5 0.4 2.1 2 0 0 2 2 2 1 Gammaherpesvirus protein of unknown function (DUF848) NPV_P10 PF05531.7 GAP92243.1 - 0.0084 16.3 0.5 3.5 7.9 0.0 2.7 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein FlxA PF14282.1 GAP92243.1 - 0.0094 15.8 4.1 0.017 15.0 2.8 1.4 1 0 0 1 1 1 1 FlxA-like protein Prefoldin_2 PF01920.15 GAP92243.1 - 0.033 13.9 2.7 0.62 9.8 0.0 3.0 2 1 1 3 3 3 0 Prefoldin subunit FliD_C PF07195.7 GAP92243.1 - 0.034 13.4 1.3 0.35 10.1 0.0 2.4 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus HR1 PF02185.11 GAP92243.1 - 0.049 13.3 2.6 0.28 10.9 0.0 2.9 3 0 0 3 3 3 0 Hr1 repeat Reo_sigmaC PF04582.7 GAP92243.1 - 0.052 12.7 1.9 2.4 7.2 0.0 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF4201 PF13870.1 GAP92243.1 - 0.054 12.9 3.4 0.13 11.6 2.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) DUF342 PF03961.8 GAP92243.1 - 0.057 11.8 0.7 0.1 11.0 0.4 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF342) TMF_DNA_bd PF12329.3 GAP92243.1 - 0.069 12.9 2.5 2.1 8.2 0.1 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 GAP92243.1 - 0.11 12.0 4.3 0.94 9.0 3.0 2.3 1 1 0 1 1 1 0 IncA protein OmpH PF03938.9 GAP92243.1 - 0.12 12.3 4.8 0.21 11.5 3.2 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) CENP-F_leu_zip PF10473.4 GAP92243.1 - 0.29 10.9 5.6 4.4 7.1 2.0 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TBPIP PF07106.8 GAP92243.1 - 0.39 10.2 3.6 1.4 8.4 0.5 2.5 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4140 PF13600.1 GAP92243.1 - 0.39 11.1 4.8 1.6 9.2 0.0 3.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF972 PF06156.8 GAP92243.1 - 0.58 10.5 2.7 3.7 7.9 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Atg14 PF10186.4 GAP92243.1 - 0.72 8.7 4.5 1 8.2 3.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_TATA_bd PF12325.3 GAP92243.1 - 2.5 7.8 10.3 2.3 7.9 0.7 2.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding WD40 PF00400.27 GAP92244.1 - 5.6e-38 127.4 4.2 2.3e-06 27.2 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 GAP92244.1 - 1.1e-14 53.8 0.7 4e-14 52.0 0.5 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAP92244.1 - 1.4e-08 34.1 1.4 1.6e-08 33.9 0.1 1.9 2 0 0 2 2 2 1 F-box domain BBS2_Mid PF14783.1 GAP92244.1 - 0.0042 16.8 0.0 3.7 7.3 0.0 3.7 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region PH_10 PF15411.1 GAP92245.1 - 3.2e-42 143.3 0.9 5.6e-42 142.5 0.6 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 GAP92245.1 - 3.3e-33 115.0 1.5 4e-33 114.8 0.1 1.8 2 0 0 2 2 2 1 RhoGEF domain CDC24 PF06395.6 GAP92245.1 - 3.5e-29 100.6 0.0 7.5e-29 99.6 0.0 1.6 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.19 GAP92245.1 - 4.5e-10 39.0 0.0 9.8e-10 37.9 0.0 1.5 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 GAP92245.1 - 0.019 15.1 0.3 0.045 13.9 0.2 1.6 1 0 0 1 1 1 0 PH domain Herpes_IE1 PF07340.6 GAP92245.1 - 0.087 11.2 2.2 0.26 9.7 0.0 2.4 3 0 0 3 3 3 0 Cytomegalovirus IE1 protein DUF1903 PF08991.5 GAP92246.1 - 0.09 12.9 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) MFS_1 PF07690.11 GAP92247.1 - 1.6e-24 86.2 52.7 4.2e-14 52.0 16.5 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Med18 PF09637.5 GAP92248.1 - 4.8e-27 95.0 0.0 5.8e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Med18 protein DUF688 PF05097.7 GAP92248.1 - 0.51 9.2 1.8 0.73 8.7 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF688) Ank_2 PF12796.2 GAP92249.1 - 1.2e-111 365.2 9.0 1.8e-25 89.0 0.0 6.5 3 2 4 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 GAP92249.1 - 5.4e-91 294.1 5.0 1.4e-09 37.2 0.0 14.3 13 1 0 13 13 13 13 Ankyrin repeat Ank_4 PF13637.1 GAP92249.1 - 6.2e-58 192.2 7.0 6.4e-12 45.6 0.0 10.0 2 2 6 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP92249.1 - 3.1e-55 178.5 0.9 2e-05 24.3 0.0 13.9 14 0 0 14 14 14 9 Ankyrin repeat Ank_5 PF13857.1 GAP92249.1 - 6.1e-52 172.4 4.3 1.6e-08 34.5 0.0 8.9 5 3 6 11 11 11 8 Ankyrin repeats (many copies) NACHT PF05729.7 GAP92249.1 - 3.9e-07 29.8 0.0 1.7e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 GAP92249.1 - 0.0004 20.5 0.0 0.0013 18.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain Mur_ligase PF01225.20 GAP92249.1 - 0.012 15.6 0.0 23 5.1 0.0 4.6 2 1 2 4 4 4 0 Mur ligase family, catalytic domain AAA PF00004.24 GAP92249.1 - 0.041 14.0 0.0 0.16 12.1 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mtc PF03820.12 GAP92250.1 - 4.8e-89 298.0 0.0 1.1e-88 296.8 0.0 1.5 1 1 0 1 1 1 1 Tricarboxylate carrier Aa_trans PF01490.13 GAP92251.1 - 4.9e-39 133.9 32.6 5.6e-39 133.7 22.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 GAP92251.1 - 0.0087 14.6 48.7 0.3 9.5 33.8 2.1 1 1 0 1 1 1 1 Amino acid permease Pro_dh PF01619.13 GAP92253.1 - 1.5e-14 53.7 0.0 6.7e-14 51.5 0.0 1.9 1 1 0 1 1 1 1 Proline dehydrogenase Halo_GVPC PF05465.8 GAP92253.1 - 0.021 14.7 1.5 0.021 14.7 1.0 2.0 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat Aldedh PF00171.17 GAP92255.1 - 2e-94 316.5 0.0 2.3e-94 316.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.13 GAP92256.1 - 2e-10 39.9 0.0 3.8e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP92256.1 - 2e-08 34.0 13.6 4.2e-08 32.9 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 GAP92257.1 - 3e-49 167.7 0.0 4.1e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DHH PF01368.15 GAP92259.1 - 1.4e-07 31.2 0.1 2.9e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 DHH family NUDIX PF00293.23 GAP92260.1 - 1.7e-14 53.6 0.0 2.2e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Aminotran_5 PF00266.14 GAP92260.1 - 0.053 12.2 0.0 0.069 11.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V RNA_pol_Rpb5_C PF01191.14 GAP92260.1 - 0.089 12.3 0.7 18 5.0 0.0 3.1 3 0 0 3 3 3 0 RNA polymerase Rpb5, C-terminal domain SAPS PF04499.10 GAP92261.1 - 1.6e-190 633.8 0.0 5.5e-190 632.0 0.0 1.9 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein Condensation PF00668.15 GAP92262.1 - 5.3e-86 288.1 2.5 1.8e-29 102.5 0.0 3.6 3 1 0 3 3 3 3 Condensation domain AMP-binding PF00501.23 GAP92262.1 - 1.3e-32 112.7 0.0 3e-32 111.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 GAP92262.1 - 3e-11 43.4 2.6 0.0002 21.5 0.0 3.0 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAP92262.1 - 0.0026 18.6 0.0 0.41 11.6 0.0 2.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AA_permease PF00324.16 GAP92264.1 - 1.3e-140 468.9 49.1 1.5e-140 468.7 34.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAP92264.1 - 4e-35 121.1 51.2 5.4e-35 120.7 35.5 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 GAP92265.1 - 1.2e-32 113.0 27.0 9.8e-32 110.0 18.8 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily GCFC PF07842.7 GAP92266.1 - 3.1e-72 243.2 0.5 6.6e-72 242.1 0.1 1.7 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 GAP92266.1 - 3.5e-14 52.3 1.6 1.4e-13 50.3 0.2 2.5 2 0 0 2 2 2 1 G-patch domain TIP_N PF12457.3 GAP92266.1 - 3.7e-14 52.7 8.5 3.7e-14 52.7 5.9 3.6 2 1 1 3 3 3 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.2 GAP92266.1 - 3.2e-05 23.6 0.3 3.2e-05 23.6 0.2 2.8 3 0 0 3 3 3 1 DExH-box splicing factor binding site Sld5 PF05916.6 GAP92267.1 - 1.7e-12 47.5 0.0 2.3e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Sod_Fe_C PF02777.13 GAP92268.1 - 1.2e-39 134.4 0.7 2.1e-39 133.6 0.2 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 GAP92268.1 - 1.3e-30 105.4 2.5 2.3e-30 104.6 1.7 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain SET PF00856.23 GAP92270.1 - 0.0067 16.7 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 SET domain Glyco_hydro_61 PF03443.9 GAP92271.1 - 2.3e-71 240.1 0.7 4.2e-71 239.2 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 GAP92271.1 - 2.3e-12 46.3 11.3 6.6e-12 44.8 7.8 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Sporozoite_P67 PF05642.6 GAP92271.1 - 1.9 6.2 7.8 2 6.1 5.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Fer2 PF00111.22 GAP92273.1 - 1.5e-06 27.8 0.3 2.8e-06 26.9 0.2 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_6 PF00970.19 GAP92273.1 - 2.3e-06 27.6 0.0 4.5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain MOSC PF03473.12 GAP92273.1 - 1.4e-05 24.5 0.1 2.5e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 MOSC domain NAD_binding_1 PF00175.16 GAP92273.1 - 0.00025 21.5 0.0 0.00052 20.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain p450 PF00067.17 GAP92275.1 - 1.4e-62 211.7 0.0 1.8e-62 211.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1162 PF06650.7 GAP92277.1 - 6.5e-91 304.3 0.1 3.2e-87 292.2 0.0 3.5 4 0 0 4 4 4 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 GAP92277.1 - 1.7e-41 140.4 0.0 5.9e-41 138.7 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 GAP92277.1 - 1.6e-05 24.9 0.0 7.9e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 ATG C terminal domain DUF3429 PF11911.3 GAP92278.1 - 4.8e-40 136.8 10.6 6.6e-40 136.3 7.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Peptidase_S49_N PF08496.5 GAP92278.1 - 0.06 13.1 2.2 0.095 12.4 1.5 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NAD_binding_1 PF00175.16 GAP92279.1 - 2.7e-10 40.7 0.0 6.2e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.17 GAP92279.1 - 1.1e-07 32.1 0.0 1.9e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Globin FAD_binding_6 PF00970.19 GAP92279.1 - 1.2e-07 31.7 0.0 2.4e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.3 GAP92279.1 - 9.8e-06 25.3 0.0 2.7e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.7 GAP92279.1 - 0.00021 21.1 0.3 0.0051 16.7 0.3 2.7 2 1 1 3 3 3 1 Ferric reductase NAD binding domain ketoacyl-synt PF00109.21 GAP92280.1 - 4.2e-74 249.2 0.0 9.1e-74 248.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAP92280.1 - 3.4e-49 167.9 0.0 9.9e-49 166.3 0.0 1.7 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 GAP92280.1 - 1.3e-42 146.0 0.0 2.3e-42 145.1 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 GAP92280.1 - 3.3e-42 144.1 0.1 9.7e-42 142.6 0.1 1.9 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 GAP92280.1 - 8e-38 129.9 0.5 2.8e-37 128.1 0.1 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAP92280.1 - 8.1e-31 106.3 0.0 2e-30 105.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 GAP92280.1 - 0.00022 21.4 0.0 0.001 19.2 0.0 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 GAP92280.1 - 0.0029 18.1 0.1 1.1 9.8 0.0 3.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP92280.1 - 0.03 14.8 0.0 0.24 11.8 0.0 2.7 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 GAP92280.1 - 0.038 14.4 0.0 0.63 10.5 0.0 2.9 3 0 0 3 3 3 0 Methyltransferase domain Thiolase_N PF00108.18 GAP92280.1 - 0.081 11.8 0.1 0.15 11.0 0.1 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain Meth_synt_1 PF08267.7 GAP92280.1 - 0.45 9.7 0.0 0.79 8.9 0.0 1.3 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain DUF566 PF04484.7 GAP92281.1 - 0.96 8.8 11.7 0.099 12.1 0.6 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF566) PRKCSH PF07915.8 GAP92282.1 - 1.4e-19 70.6 0.8 2.9e-19 69.6 0.0 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 GAP92282.1 - 0.057 12.9 0.1 5.7 6.3 0.1 2.3 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein ATG27 PF09451.5 GAP92282.1 - 0.41 9.8 0.0 0.41 9.8 0.0 2.0 3 0 0 3 3 3 0 Autophagy-related protein 27 Microtub_assoc PF07989.6 GAP92283.1 - 0.26 11.1 8.4 0.022 14.5 2.3 1.9 2 1 0 2 2 2 0 Microtubule associated Tmemb_cc2 PF10267.4 GAP92283.1 - 4.5 5.7 14.9 0.025 13.1 2.7 2.1 1 1 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein DUF1922 PF09082.5 GAP92284.1 - 0.12 12.4 3.3 0.29 11.2 2.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1922) NARP1 PF12569.3 GAP92285.1 - 2.2 6.9 10.1 2.4 6.8 7.0 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Merozoite_SPAM PF07133.6 GAP92285.1 - 4.5 7.1 23.2 5.5 6.8 16.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CLN3 PF02487.12 GAP92286.1 - 2.5e-105 352.5 14.2 1.2e-102 343.7 9.8 2.2 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.11 GAP92286.1 - 1.1e-05 24.3 33.0 0.00011 21.1 9.6 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2183 PF09949.4 GAP92287.1 - 3.6e-32 110.2 0.0 1.2e-31 108.6 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) RRM_1 PF00076.17 GAP92288.1 - 1.1e-23 82.6 0.5 6.6e-11 41.6 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP92288.1 - 1.1e-14 54.1 0.1 2.5e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP92288.1 - 3.3e-12 46.0 0.2 6.8e-07 29.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.1 GAP92288.1 - 0.086 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) DUF1866 PF08952.6 GAP92288.1 - 0.11 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) ATP-synt_D PF01813.12 GAP92289.1 - 1.3e-64 217.3 1.3 1.8e-64 216.9 0.9 1.1 1 0 0 1 1 1 1 ATP synthase subunit D GAS PF13851.1 GAP92289.1 - 0.16 11.1 5.1 0.44 9.6 0.0 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 GAP92289.1 - 0.17 10.5 3.6 2.2 6.8 1.1 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Ribosomal_L6e PF01159.14 GAP92289.1 - 0.5 10.6 4.2 0.99 9.6 2.2 2.0 1 1 1 2 2 2 0 Ribosomal protein L6e Viral_P18 PF04521.8 GAP92289.1 - 1.6 8.1 4.4 5.4 6.4 0.2 2.3 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Suf PF05843.9 GAP92290.1 - 2.8e-11 43.7 7.9 0.035 13.8 0.8 6.6 3 2 1 5 5 5 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 GAP92290.1 - 2.5e-09 36.9 21.6 2.7 8.8 0.0 11.4 10 3 3 13 13 13 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAP92290.1 - 1e-08 34.9 0.2 2.6 8.0 0.0 7.3 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.1 GAP92290.1 - 7.6e-07 28.4 7.0 3.4e-05 23.0 1.1 4.1 2 2 2 4 4 4 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 GAP92290.1 - 0.00013 21.7 10.8 1.3 8.8 0.1 6.6 7 0 0 7 7 7 2 Mad3/BUB1 homology region 1 NRDE-2 PF08424.5 GAP92290.1 - 0.00026 19.9 9.4 0.037 12.9 0.1 5.5 2 2 3 5 5 5 2 NRDE-2, necessary for RNA interference RPN7 PF10602.4 GAP92290.1 - 0.0011 18.4 0.6 0.0091 15.3 0.1 2.9 4 1 0 4 4 4 1 26S proteasome subunit RPN7 TPR_2 PF07719.12 GAP92290.1 - 0.0061 16.3 13.4 3.7 7.6 0.0 6.9 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAP92290.1 - 0.0079 15.9 6.4 0.76 9.6 0.0 5.6 7 0 0 7 7 6 1 Tetratricopeptide repeat PPR_3 PF13812.1 GAP92290.1 - 0.0097 16.1 0.1 0.17 12.2 0.0 3.2 2 0 0 2 2 1 1 Pentatricopeptide repeat domain TPR_11 PF13414.1 GAP92290.1 - 0.038 13.6 13.4 1.7 8.3 0.0 6.4 10 0 0 10 10 8 0 TPR repeat SHNi-TPR PF10516.4 GAP92290.1 - 0.054 12.7 0.0 1.2 8.4 0.0 2.9 3 0 0 3 3 3 0 SHNi-TPR TPR_7 PF13176.1 GAP92290.1 - 0.35 10.7 7.4 11 6.0 0.0 6.2 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAP92290.1 - 0.51 11.0 19.1 0.66 10.7 0.0 6.8 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 GAP92290.1 - 0.78 10.3 9.2 3.4 8.3 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Sorting_nexin PF03700.8 GAP92291.1 - 0.095 12.8 0.9 0.14 12.2 0.5 1.3 1 1 0 1 1 1 0 Sorting nexin, N-terminal domain DUF1675 PF07897.6 GAP92291.1 - 0.32 10.8 4.6 0.36 10.6 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF605 PF04652.11 GAP92291.1 - 0.57 9.5 11.8 0.68 9.2 8.2 1.0 1 0 0 1 1 1 0 Vta1 like DUF1908 PF08926.6 GAP92291.1 - 0.87 8.2 4.2 0.51 9.0 1.3 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1908) HTH_33 PF13592.1 GAP92291.1 - 4.2 6.9 6.8 4.3 6.9 0.1 2.6 2 1 1 3 3 3 0 Winged helix-turn helix Pex14_N PF04695.8 GAP92291.1 - 8.5 6.4 11.8 0.65 10.0 3.6 1.9 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Nuf2 PF03800.9 GAP92293.1 - 8.8e-44 149.0 0.1 8.8e-44 149.0 0.0 2.4 3 0 0 3 3 3 1 Nuf2 family Reo_sigmaC PF04582.7 GAP92293.1 - 2.1 7.4 4.7 2.9 6.9 2.4 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Bacillus_HBL PF05791.6 GAP92293.1 - 5.8 6.2 22.7 0.8 9.0 2.6 3.8 2 2 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF3584 PF12128.3 GAP92293.1 - 7.4 3.7 39.3 32 1.6 26.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) BLOC1_2 PF10046.4 GAP92293.1 - 8.9 6.5 29.7 0.49 10.5 5.5 4.6 1 1 5 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Thioredoxin PF00085.15 GAP92295.1 - 2.3e-25 88.2 0.1 2.7e-25 88.0 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 GAP92295.1 - 1.5e-05 25.1 0.2 0.00023 21.3 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 GAP92295.1 - 2.4e-05 24.3 0.0 0.0026 17.8 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 GAP92295.1 - 2.5e-05 23.8 0.0 2.9e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 GAP92295.1 - 0.002 18.1 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 GAP92295.1 - 0.0093 15.5 0.1 0.034 13.7 0.0 1.6 1 1 1 2 2 2 1 Redoxin Thioredoxin_3 PF13192.1 GAP92295.1 - 0.0099 15.6 0.0 0.017 14.9 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin domain Glutaredoxin PF00462.19 GAP92295.1 - 0.034 14.1 0.0 0.056 13.4 0.0 1.5 1 1 0 1 1 1 0 Glutaredoxin AhpC-TSA PF00578.16 GAP92295.1 - 0.034 13.8 0.0 0.039 13.6 0.0 1.1 1 0 0 1 1 1 0 AhpC/TSA family Acetyltransf_1 PF00583.19 GAP92296.1 - 6.2e-09 35.7 0.1 1.5e-08 34.5 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 GAP92296.1 - 1.3e-07 31.5 1.4 3.1e-05 23.8 0.1 2.7 2 1 1 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAP92296.1 - 1.4e-07 31.6 2.5 1.7e-07 31.3 0.4 2.1 2 2 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAP92296.1 - 0.0013 18.8 0.0 0.0026 17.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAP92296.1 - 0.015 15.2 0.5 0.038 13.8 0.0 1.9 3 0 0 3 3 3 0 GCN5-related N-acetyl-transferase FR47 PF08445.5 GAP92296.1 - 0.06 13.0 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Pkinase PF00069.20 GAP92297.1 - 8.1e-45 152.9 0.0 1.1e-44 152.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP92297.1 - 1.3e-25 89.9 0.0 1.8e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 GAP92297.1 - 0.00029 19.9 0.0 0.0014 17.7 0.0 2.0 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 GAP92297.1 - 0.24 10.1 0.1 0.38 9.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_Tyr PF07714.12 GAP92298.1 - 0.0039 16.3 0.0 0.0064 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAP92298.1 - 0.083 12.0 0.0 0.31 10.1 0.0 1.8 1 1 0 1 1 1 0 Protein kinase domain Cu_bind_like PF02298.12 GAP92299.1 - 0.077 12.8 0.3 0.36 10.6 0.1 2.1 2 1 0 2 2 2 0 Plastocyanin-like domain SUR7 PF06687.7 GAP92300.1 - 2.8e-24 85.8 5.8 3.4e-24 85.6 4.0 1.0 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 GAP92300.1 - 1.4 8.6 12.4 0.13 11.9 4.0 2.1 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Zn_clus PF00172.13 GAP92301.1 - 6.1e-07 29.2 8.7 1.4e-06 28.0 6.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAP92301.1 - 9.9e-05 21.3 0.3 0.00046 19.1 0.0 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain AFG1_ATPase PF03969.11 GAP92302.1 - 2e-96 322.9 0.0 1.2e-90 303.9 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 GAP92302.1 - 3.3e-05 23.9 0.1 0.027 14.4 0.0 2.7 1 1 0 2 2 2 2 AAA ATPase domain Bac_DnaA PF00308.13 GAP92302.1 - 0.0007 19.3 0.3 0.11 12.1 0.1 2.4 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_22 PF13401.1 GAP92302.1 - 0.0034 17.5 0.1 0.019 15.1 0.0 2.3 3 1 0 3 3 3 1 AAA domain AAA_14 PF13173.1 GAP92302.1 - 0.0043 16.9 0.0 0.0096 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 GAP92302.1 - 0.0079 16.4 0.1 0.059 13.5 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 GAP92302.1 - 0.019 15.0 0.0 0.29 11.1 0.0 2.8 2 2 1 3 3 3 0 Sigma-54 interaction domain AAA_5 PF07728.9 GAP92302.1 - 0.033 13.9 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 GAP92302.1 - 0.034 14.3 0.2 0.2 11.8 0.0 2.4 2 1 1 3 3 3 0 RNA helicase EF-hand_7 PF13499.1 GAP92302.1 - 0.084 13.0 0.1 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair NACHT PF05729.7 GAP92302.1 - 0.096 12.3 0.0 0.24 11.0 0.0 1.8 1 1 0 1 1 1 0 NACHT domain RAP1 PF07218.6 GAP92302.1 - 0.097 10.7 0.2 0.13 10.3 0.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) APS_kinase PF01583.15 GAP92302.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase MFS_1 PF07690.11 GAP92304.1 - 2.5e-12 46.1 42.4 4.6e-12 45.3 28.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily PolyA_pol PF01743.15 GAP92306.1 - 4.3e-25 88.3 0.1 8.8e-25 87.3 0.1 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 GAP92306.1 - 8.6e-09 34.8 0.0 2.1e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 GAP92306.1 - 0.001 18.8 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative DUF1329 PF07044.6 GAP92306.1 - 0.11 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1329) DUF2610 PF11020.3 GAP92307.1 - 0.094 12.5 0.0 0.31 10.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2610) Adaptin_N PF01602.15 GAP92308.1 - 2.1e-101 339.8 0.0 2.6e-101 339.5 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 GAP92308.1 - 6e-12 45.6 4.7 3.6e-05 23.9 0.0 5.2 4 1 2 6 6 6 3 HEAT repeats HEAT PF02985.17 GAP92308.1 - 1.2e-10 40.4 0.2 0.051 13.6 0.0 5.7 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 GAP92308.1 - 2e-05 24.9 7.9 0.017 15.6 0.0 5.5 5 1 1 6 6 6 1 HEAT-like repeat Cohesin_HEAT PF12765.2 GAP92308.1 - 0.004 17.0 0.7 0.67 9.9 0.0 3.1 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Nop14 PF04147.7 GAP92308.1 - 0.0071 14.3 25.2 0.011 13.6 17.4 1.2 1 0 0 1 1 1 1 Nop14-like family Cnd1 PF12717.2 GAP92308.1 - 0.073 12.9 0.0 0.71 9.7 0.0 2.5 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 CENP-T PF15511.1 GAP92308.1 - 0.35 10.0 14.3 0.88 8.7 9.9 1.7 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CobT PF06213.7 GAP92308.1 - 1.5 7.8 31.2 3.2 6.7 21.6 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NAD_binding_2 PF03446.10 GAP92309.1 - 1.3e-32 112.8 0.2 1.9e-32 112.3 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 GAP92309.1 - 1.5e-30 105.7 0.2 3.7e-30 104.4 0.0 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.10 GAP92309.1 - 0.0015 17.3 0.0 0.0024 16.6 0.0 1.4 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family NAD_Gly3P_dh_N PF01210.18 GAP92309.1 - 0.12 12.0 0.3 0.21 11.3 0.0 1.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF3053 PF11254.3 GAP92309.1 - 0.14 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) Reprolysin_5 PF13688.1 GAP92310.1 - 0.016 15.1 1.3 0.038 13.9 0.9 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 GAP92310.1 - 0.025 14.1 0.2 0.046 13.2 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 GAP92310.1 - 0.032 14.3 2.5 0.1 12.6 1.7 1.9 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF1025 PF06262.6 GAP92310.1 - 0.047 13.4 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase Reprolysin_3 PF13582.1 GAP92310.1 - 0.065 13.7 0.6 0.11 12.9 0.4 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M64 PF09471.5 GAP92310.1 - 0.1 12.2 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 IgA Peptidase M64 KilA-N PF04383.8 GAP92311.1 - 0.0011 18.5 0.3 0.025 14.2 0.0 2.7 2 1 0 2 2 2 1 KilA-N domain PsaN PF05479.6 GAP92311.1 - 0.07 13.1 0.7 3 7.7 0.1 2.3 2 0 0 2 2 2 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) Rho_GDI PF02115.12 GAP92312.1 - 5.3e-54 182.6 0.0 8.3e-54 182.0 0.0 1.3 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Metallophos PF00149.23 GAP92313.1 - 6e-42 143.3 0.8 7.3e-42 143.0 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PI31_Prot_N PF11566.3 GAP92315.1 - 1.8e-30 105.5 0.0 2.4e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 GAP92315.1 - 2.7e-10 40.7 24.5 2.7e-10 40.7 17.0 3.4 3 2 0 3 3 3 1 PI31 proteasome regulator HORMA PF02301.13 GAP92316.1 - 2.3e-21 76.2 0.0 6.3e-21 74.8 0.0 1.6 1 1 0 1 1 1 1 HORMA domain S-antigen PF05756.6 GAP92316.1 - 0.018 15.0 6.3 0.031 14.2 4.4 1.3 1 0 0 1 1 1 0 S-antigen protein FSIP1 PF15554.1 GAP92316.1 - 0.025 13.4 3.0 0.034 12.9 2.1 1.1 1 0 0 1 1 1 0 FSIP1 family Nop14 PF04147.7 GAP92316.1 - 0.049 11.5 5.2 0.06 11.2 3.6 1.0 1 0 0 1 1 1 0 Nop14-like family Med17 PF10156.4 GAP92316.1 - 0.073 11.3 1.7 0.1 10.8 1.2 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex Voldacs PF03517.8 GAP92316.1 - 0.093 12.5 2.2 0.15 11.9 1.5 1.2 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling CDC45 PF02724.9 GAP92316.1 - 0.27 9.2 3.1 0.37 8.7 2.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2890 PF11081.3 GAP92316.1 - 0.43 10.6 3.0 0.61 10.1 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Sigma70_ner PF04546.8 GAP92316.1 - 1 8.9 7.0 1.5 8.3 4.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Daxx PF03344.10 GAP92316.1 - 1.1 7.6 9.3 1.5 7.2 6.5 1.1 1 0 0 1 1 1 0 Daxx Family Sporozoite_P67 PF05642.6 GAP92316.1 - 1.2 6.8 9.1 1.8 6.3 6.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2457 PF10446.4 GAP92316.1 - 6.9 5.2 18.5 9.5 4.8 12.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) IBN_N PF03810.14 GAP92317.1 - 1.1e-08 34.7 0.0 8.7e-08 31.9 0.0 2.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 GAP92317.1 - 3e-06 27.2 1.9 0.0023 17.8 0.0 4.1 4 0 0 4 4 4 2 Exportin 1-like protein CAS_CSE1 PF03378.10 GAP92317.1 - 2.1e-05 23.0 0.0 7.1e-05 21.2 0.0 1.8 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus RhoGEF PF00621.15 GAP92318.1 - 1.5e-24 86.8 0.3 4.9e-24 85.1 0.0 2.0 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.3 GAP92318.1 - 0.014 14.8 0.0 0.027 13.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) Baculo_PEP_C PF04513.7 GAP92318.1 - 0.081 12.7 1.7 0.3 10.9 1.2 2.0 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.6 GAP92318.1 - 4.1 7.2 7.2 0.54 10.1 1.4 2.3 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2036 PF09724.4 GAP92319.1 - 2.5e-08 33.4 0.0 2.9e-08 33.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) DUF498 PF04430.9 GAP92319.1 - 0.042 13.4 0.0 3.9 7.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF498/DUF598) IBR PF01485.16 GAP92320.1 - 1.6e-07 31.0 27.1 0.00018 21.2 4.2 3.5 3 0 0 3 3 3 3 IBR domain Acetyltransf_7 PF13508.1 GAP92321.1 - 0.01 15.9 0.0 0.037 14.1 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAP92321.1 - 0.021 14.6 0.1 0.11 12.3 0.0 2.2 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Cpn60_TCP1 PF00118.19 GAP92322.1 - 9e-143 476.3 12.4 1e-142 476.1 8.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Metallophos PF00149.23 GAP92323.1 - 1.1e-13 51.0 0.4 7e-13 48.4 0.3 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAP92323.1 - 2.8e-08 33.7 0.0 1e-07 31.9 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MMS1_N PF10433.4 GAP92326.1 - 2.1e-77 260.4 0.0 3.1e-77 259.8 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 GAP92326.1 - 1.2e-65 221.6 0.1 6e-65 219.4 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region UCR_TM PF02921.9 GAP92326.1 - 1e-17 64.1 0.5 2.9e-17 62.6 0.3 1.8 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 GAP92326.1 - 2.3e-16 59.1 0.0 5.3e-16 57.9 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain GNT-I PF03071.10 GAP92326.1 - 0.074 11.5 0.1 0.12 10.9 0.1 1.2 1 0 0 1 1 1 0 GNT-I family Ank_2 PF12796.2 GAP92327.1 - 2.4e-69 229.7 14.7 3.8e-19 68.8 1.0 4.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAP92327.1 - 2.9e-59 194.0 19.1 3.2e-07 29.8 0.2 8.1 8 0 0 8 8 8 8 Ankyrin repeat Ank_3 PF13606.1 GAP92327.1 - 1.8e-46 151.4 5.7 4.6e-05 23.2 0.0 8.1 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.1 GAP92327.1 - 2.7e-45 151.9 9.8 8.8e-11 42.0 0.1 5.4 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP92327.1 - 1.1e-36 123.9 14.5 6.6e-09 35.7 0.1 8.2 3 2 5 8 8 8 8 Ankyrin repeats (many copies) gag-asp_proteas PF13975.1 GAP92327.1 - 0.04 13.7 0.4 24 4.8 0.0 3.5 4 0 0 4 4 4 0 gag-polyprotein putative aspartyl protease FA PF08736.6 GAP92327.1 - 0.16 11.7 0.0 0.41 10.4 0.0 1.7 1 0 0 1 1 1 0 FERM adjacent (FA) MTP18 PF10558.4 GAP92328.1 - 5.3e-69 230.8 0.1 6.8e-69 230.5 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) zf-AN1 PF01428.11 GAP92329.1 - 1.2e-22 79.4 19.6 6.6e-12 45.1 5.7 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 GAP92329.1 - 0.0089 15.8 15.3 0.01 15.7 1.1 2.5 2 1 0 2 2 2 2 IBR domain Transp_Tc5_C PF04236.10 GAP92329.1 - 0.02 15.1 14.4 0.12 12.6 3.0 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Rad4 PF03835.10 GAP92330.1 - 2.2e-33 114.6 0.1 2.2e-33 114.6 0.1 2.2 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 GAP92330.1 - 3.3e-27 94.0 0.1 5.5e-27 93.2 0.1 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 GAP92330.1 - 5.2e-20 70.7 0.6 1.6e-19 69.1 0.4 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 GAP92330.1 - 1.4e-14 54.1 0.2 1.4e-14 54.1 0.1 3.7 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 GAP92330.1 - 0.0013 18.9 0.0 0.004 17.3 0.0 1.9 1 1 0 1 1 1 1 Transglutaminase-like superfamily Zip PF02535.17 GAP92331.1 - 0.038 12.9 4.0 0.05 12.6 2.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter BAF1_ABF1 PF04684.8 GAP92331.1 - 0.35 9.6 10.8 0.52 9.0 7.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Innate_immun PF12782.2 GAP92331.1 - 0.63 9.2 10.5 0.021 14.0 3.3 1.6 2 0 0 2 2 2 0 Invertebrate innate immunity transcript family PhzC-PhzF PF02567.11 GAP92332.1 - 1.6e-36 125.9 2.8 1.6e-35 122.7 1.9 2.0 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Ion_trans PF00520.26 GAP92333.1 - 2.2e-05 23.7 16.6 2.2e-05 23.7 11.5 2.6 1 1 1 2 2 2 1 Ion transport protein DUF3814 PF12769.2 GAP92333.1 - 0.00095 19.2 0.5 0.0023 18.0 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3814) Glycophorin_A PF01102.13 GAP92334.1 - 0.0019 17.9 7.3 0.0019 17.9 5.1 2.0 1 1 1 2 2 2 1 Glycophorin A DUF1191 PF06697.7 GAP92334.1 - 0.025 13.3 0.0 0.038 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) EphA2_TM PF14575.1 GAP92334.1 - 0.031 14.6 0.0 0.14 12.5 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Sporozoite_P67 PF05642.6 GAP92334.1 - 0.12 10.2 20.8 0.19 9.5 14.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Macoilin PF09726.4 GAP92334.1 - 0.51 8.5 12.9 0.78 7.9 8.9 1.2 1 0 0 1 1 1 0 Transmembrane protein MCLC PF05934.6 GAP92334.1 - 0.77 7.9 4.6 0.99 7.6 3.2 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF566 PF04484.7 GAP92334.1 - 9.9 5.5 14.5 22 4.4 10.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF566) Aldose_epim PF01263.15 GAP92336.1 - 3.9e-46 157.5 0.2 4.4e-46 157.3 0.2 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Methyltransf_16 PF10294.4 GAP92337.1 - 7.7e-25 87.3 0.0 1.1e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 GAP92337.1 - 6.4e-09 35.3 0.0 8.2e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 GAP92337.1 - 2e-06 27.3 0.1 3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 GAP92337.1 - 3.6e-06 27.5 0.1 6.2e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 GAP92337.1 - 8.8e-05 22.1 0.0 0.00018 21.1 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.1 GAP92337.1 - 0.0017 18.1 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP92337.1 - 0.011 15.7 0.2 0.022 14.7 0.2 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 GAP92337.1 - 0.018 15.4 0.1 0.036 14.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 GAP92337.1 - 0.11 12.9 0.1 0.24 11.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 GAP92337.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_31 PF13847.1 GAP92337.1 - 0.14 11.7 0.2 0.34 10.4 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 GAP92337.1 - 0.16 11.5 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Bromodomain PF00439.20 GAP92339.1 - 9.1e-36 121.6 1.2 7e-19 67.5 0.5 2.6 2 0 0 2 2 2 2 Bromodomain Utp12 PF04003.7 GAP92340.1 - 6.4e-20 71.0 0.0 9.4e-20 70.5 0.0 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family MgsA_C PF12002.3 GAP92341.1 - 1.2e-59 200.7 0.0 3.2e-59 199.4 0.0 1.6 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 GAP92341.1 - 2e-14 53.9 0.1 3.9e-14 52.9 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 GAP92341.1 - 9.3e-11 41.2 0.0 3.3e-10 39.3 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 GAP92341.1 - 8e-07 28.6 0.1 2.7e-05 23.6 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.1 GAP92341.1 - 2.9e-06 27.4 0.2 1.4e-05 25.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAP92341.1 - 1.6e-05 24.9 0.6 0.0095 15.9 0.0 3.3 2 1 1 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.16 GAP92341.1 - 0.00013 21.2 0.1 0.074 12.2 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 GAP92341.1 - 0.00017 21.4 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 GAP92341.1 - 0.00044 20.0 0.1 0.03 14.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 GAP92341.1 - 0.00079 18.4 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.8 GAP92341.1 - 0.0011 17.8 0.0 0.0086 14.8 0.0 1.9 2 0 0 2 2 2 1 TIP49 C-terminus AAA_19 PF13245.1 GAP92341.1 - 0.0015 18.2 0.1 0.0041 16.8 0.0 1.9 2 0 0 2 2 1 1 Part of AAA domain DNA_pol3_delta2 PF13177.1 GAP92341.1 - 0.0026 17.4 0.0 0.26 10.9 0.0 2.6 2 1 1 3 3 3 1 DNA polymerase III, delta subunit Sigma54_activ_2 PF14532.1 GAP92341.1 - 0.0028 17.6 0.0 0.006 16.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_17 PF13207.1 GAP92341.1 - 0.0051 17.6 0.0 0.014 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 GAP92341.1 - 0.0095 15.5 0.0 0.1 12.2 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 GAP92341.1 - 0.016 15.0 0.4 2.1 8.1 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit CPT PF07931.7 GAP92341.1 - 0.025 14.2 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_10 PF12846.2 GAP92341.1 - 0.033 13.6 2.2 3.9 6.8 0.1 3.1 2 1 0 3 3 3 0 AAA-like domain IstB_IS21 PF01695.12 GAP92341.1 - 0.043 13.2 0.0 0.089 12.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein SKI PF01202.17 GAP92341.1 - 0.061 13.1 0.1 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase NB-ARC PF00931.17 GAP92341.1 - 0.074 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.1 GAP92341.1 - 0.1 12.5 0.1 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-TRAF PF02176.13 GAP92341.1 - 0.13 12.7 0.2 0.24 11.8 0.1 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger PduV-EutP PF10662.4 GAP92341.1 - 0.13 11.7 0.2 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TrwB_AAD_bind PF10412.4 GAP92341.1 - 0.13 10.8 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Rad17 PF03215.10 GAP92341.1 - 0.18 10.4 0.0 3.3 6.2 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Fe-S_biosyn PF01521.15 GAP92342.1 - 1.3e-19 70.1 0.0 1.7e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF1741 PF08427.5 GAP92343.1 - 6.3e-82 274.5 0.2 6.3e-82 274.5 0.1 1.9 3 0 0 3 3 3 1 Domain of unknown function (DUF1741) zf-CCCH PF00642.19 GAP92346.1 - 0.0022 17.6 0.9 0.0022 17.6 0.7 3.1 4 0 0 4 4 4 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Beta-lactamase PF00144.19 GAP92347.1 - 1.2e-50 172.4 0.0 1.8e-50 171.8 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 GAP92347.1 - 2.6e-09 36.8 0.1 5.2e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Glyco_hydro_2 PF00703.16 GAP92348.1 - 1.8e-06 28.3 0.0 8.4e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 GAP92348.1 - 2.4e-06 27.2 0.0 8.3e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 GAP92348.1 - 2.7e-05 23.2 0.1 6.8e-05 21.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Zn_clus PF00172.13 GAP92349.1 - 5.7e-06 26.1 8.5 5.7e-06 26.1 5.9 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Plasmodium_Vir PF05795.6 GAP92349.1 - 0.16 11.1 0.1 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Senescence_reg PF04520.8 GAP92349.1 - 0.19 12.2 3.2 0.47 10.9 1.3 2.1 2 0 0 2 2 2 0 Senescence regulator Med3 PF11593.3 GAP92349.1 - 0.32 10.1 15.4 0.016 14.4 6.9 1.5 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Ilar_coat PF01787.11 GAP92349.1 - 1.2 8.7 4.9 1.9 7.9 3.4 1.3 1 0 0 1 1 1 0 Ilarvirus coat protein FAM75 PF14650.1 GAP92349.1 - 1.4 8.2 14.8 2.3 7.4 10.2 1.3 1 0 0 1 1 1 0 FAM75 family PAT1 PF09770.4 GAP92349.1 - 2.8 6.0 13.2 3.8 5.6 9.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2360 PF10152.4 GAP92349.1 - 3.9 7.7 7.9 8.4 6.6 5.5 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF1517 PF07466.6 GAP92349.1 - 8.7 5.2 11.2 14 4.5 6.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) polyprenyl_synt PF00348.12 GAP92350.1 - 3.8e-56 189.8 0.0 4.8e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase p450 PF00067.17 GAP92351.1 - 1.9e-45 155.3 0.1 2e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FlbD PF06289.6 GAP92351.1 - 0.046 13.0 0.0 0.091 12.1 0.0 1.5 1 0 0 1 1 1 0 Flagellar protein (FlbD) Prenyltrans_1 PF13243.1 GAP92352.1 - 1.7e-07 31.2 0.1 0.028 14.4 0.0 3.5 3 0 0 3 3 3 2 Prenyltransferase-like Prenyltrans_2 PF13249.1 GAP92352.1 - 1.3e-06 28.7 1.0 0.98 9.8 0.0 4.7 4 1 1 5 5 5 3 Prenyltransferase-like Terpene_synth_C PF03936.11 GAP92352.1 - 0.007 15.6 0.0 0.45 9.7 0.0 2.4 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain Prenyltrans PF00432.16 GAP92352.1 - 0.077 12.5 1.5 0.92 9.1 0.0 2.9 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat Fringe PF02434.11 GAP92353.1 - 4e-08 32.7 0.1 1.4e-06 27.7 0.1 2.5 2 1 0 2 2 2 1 Fringe-like PAN_4 PF14295.1 GAP92353.1 - 0.00018 21.1 2.5 0.00053 19.6 1.7 1.8 1 0 0 1 1 1 1 PAN domain DUF604 PF04646.7 GAP92353.1 - 0.0068 15.6 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Galactosyl_T PF01762.16 GAP92353.1 - 0.098 12.2 0.0 2.9 7.4 0.0 2.3 1 1 1 2 2 2 0 Galactosyltransferase PAN_2 PF08276.6 GAP92353.1 - 0.1 12.4 1.3 0.23 11.3 0.9 1.6 1 0 0 1 1 1 0 PAN-like domain SKG6 PF08693.5 GAP92354.1 - 9.4e-06 24.8 0.7 9.4e-06 24.8 0.5 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain TMEM154 PF15102.1 GAP92354.1 - 0.058 13.1 1.7 0.093 12.4 1.2 1.4 1 0 0 1 1 1 0 TMEM154 protein family TALPID3 PF15324.1 GAP92354.1 - 3.2 4.9 4.9 4.2 4.5 3.4 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Pex14_N PF04695.8 GAP92355.1 - 0.022 14.8 3.3 0.25 11.3 0.4 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TMEM154 PF15102.1 GAP92355.1 - 2.3 7.9 7.3 4.8 6.8 5.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family Ank_2 PF12796.2 GAP92356.1 - 1.1e-33 115.3 0.1 2.9e-10 40.3 0.0 5.2 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAP92356.1 - 1.2e-28 97.4 0.1 1.6e-07 30.7 0.0 7.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 GAP92356.1 - 8.2e-24 83.5 1.9 3.5e-08 33.7 0.0 7.3 3 3 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP92356.1 - 8.2e-22 75.1 0.0 2.3e-05 24.1 0.0 7.4 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 GAP92356.1 - 6.2e-21 73.9 5.5 1.9e-09 37.4 0.1 6.9 6 1 1 7 7 7 5 Ankyrin repeats (many copies) tRNA-synt_2b PF00587.20 GAP92356.1 - 1.5e-19 70.2 0.0 2.7e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAP92356.1 - 5.5e-17 61.4 0.0 1.2e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain ProRS-C_1 PF09180.6 GAP92356.1 - 5.6e-15 55.0 0.1 1.2e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal TraC_F_IV PF11130.3 GAP92356.1 - 0.077 12.4 0.0 0.32 10.4 0.0 2.0 2 0 0 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer FAD_binding_4 PF01565.18 GAP92357.1 - 1.8e-17 63.1 0.3 4e-17 61.9 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP92357.1 - 4.2e-10 39.3 0.1 1.1e-09 38.0 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like DUF4066 PF13278.1 GAP92358.1 - 2.1e-23 82.4 0.0 2.5e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 GAP92358.1 - 4.8e-11 42.3 0.0 6.5e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 GAP92358.1 - 0.12 11.8 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I HECT PF00632.20 GAP92360.1 - 1e-74 251.6 0.0 1.4e-74 251.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF3712 PF12505.3 GAP92361.1 - 0.00013 22.0 0.0 0.0017 18.4 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3712) Fringe PF02434.11 GAP92362.1 - 2e-06 27.2 0.1 0.0024 17.1 0.2 3.0 2 1 0 2 2 2 2 Fringe-like PAN_4 PF14295.1 GAP92362.1 - 0.066 12.9 1.1 0.16 11.7 0.8 1.6 1 0 0 1 1 1 0 PAN domain PAN_1 PF00024.21 GAP92362.1 - 0.092 12.5 1.4 0.19 11.5 0.9 1.4 1 0 0 1 1 1 0 PAN domain S10_plectin PF03501.10 GAP92363.1 - 5.2e-41 138.4 0.2 6.3e-41 138.1 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Telomere_Sde2 PF13019.1 GAP92364.1 - 1.8e-66 222.8 0.1 2.6e-66 222.3 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing LacI PF00356.16 GAP92364.1 - 0.07 12.7 0.6 0.35 10.5 0.1 2.4 1 1 0 2 2 2 0 Bacterial regulatory proteins, lacI family DUF2407 PF10302.4 GAP92364.1 - 1.7 8.9 5.6 86 3.4 3.9 2.8 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain adh_short PF00106.20 GAP92365.1 - 5e-29 101.3 1.6 7.7e-29 100.7 1.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP92365.1 - 2.9e-13 49.8 0.2 5.9e-13 48.8 0.2 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAP92365.1 - 5.9e-12 45.8 0.0 7.3e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAP92365.1 - 6.2e-06 25.8 0.3 1.2e-05 24.9 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 GAP92365.1 - 0.0018 17.1 0.1 0.0029 16.5 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain FTR_C PF02741.10 GAP92365.1 - 0.0071 16.1 0.1 0.014 15.2 0.1 1.4 1 0 0 1 1 1 1 FTR, proximal lobe Eno-Rase_NADH_b PF12242.3 GAP92365.1 - 0.038 13.7 0.0 0.09 12.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF2620 PF10941.3 GAP92365.1 - 0.041 13.9 0.3 0.092 12.7 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF2620 LacAB_rpiB PF02502.13 GAP92365.1 - 0.066 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Ribose/Galactose Isomerase WD40 PF00400.27 GAP92366.1 - 1.9e-20 71.9 3.1 3e-06 26.8 0.0 6.6 6 1 1 7 7 7 4 WD domain, G-beta repeat SRA1 PF07304.6 GAP92366.1 - 2.2e-07 30.7 0.0 2.2e-07 30.7 0.0 3.4 3 1 0 3 3 3 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 GAP92366.1 - 1.3e-05 25.1 0.0 4e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Apc4_WD40 PF12894.2 GAP92366.1 - 0.085 12.3 0.0 3.9 7.0 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.17 GAP92367.1 - 6.9e-16 57.6 0.0 9e-16 57.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP92367.1 - 2.1e-11 43.6 0.0 3.1e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP92367.1 - 8.4e-11 41.5 0.0 1.2e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAP92367.1 - 0.0033 17.1 0.0 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif COX6B PF02297.12 GAP92368.1 - 4e-19 68.4 4.7 5e-19 68.0 3.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 GAP92368.1 - 0.0099 15.2 1.5 0.017 14.4 1.1 1.5 1 1 0 1 1 1 1 APOBEC-like C-terminal domain CHCH PF06747.8 GAP92368.1 - 0.034 14.0 0.7 0.081 12.8 0.5 1.6 1 1 0 1 1 1 0 CHCH domain UCR_hinge PF02320.11 GAP92368.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein L51_S25_CI-B8 PF05047.11 GAP92369.1 - 3e-19 68.5 0.1 5.1e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF2540 PF10802.3 GAP92369.1 - 0.038 13.6 0.3 0.068 12.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) C2 PF00168.25 GAP92370.1 - 2.3e-22 78.6 0.0 1.1e-14 54.0 0.0 2.6 2 0 0 2 2 2 2 C2 domain IMS PF00817.15 GAP92372.1 - 1.1e-33 116.1 0.0 1.9e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 GAP92372.1 - 2e-09 37.4 0.7 5.6e-09 36.0 0.5 1.7 1 1 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 GAP92372.1 - 0.015 15.3 0.0 0.042 13.8 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif NOA36 PF06524.7 GAP92372.1 - 0.029 13.6 1.9 0.055 12.7 1.3 1.4 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.13 GAP92372.1 - 0.14 11.2 3.6 7.2 5.6 0.0 2.3 2 0 0 2 2 2 0 Myc amino-terminal region Mucin PF01456.12 GAP92372.1 - 0.22 11.3 10.5 0.53 10.0 7.3 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein Mito_fiss_reg PF05308.6 GAP92372.1 - 0.49 9.7 2.4 0.97 8.7 1.6 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator HLH PF00010.21 GAP92373.1 - 2.4e-07 30.3 0.1 1.2e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Amidoligase_2 PF12224.3 GAP92374.1 - 1.2e-19 70.9 0.1 1.1e-12 48.1 0.0 3.2 3 0 0 3 3 3 3 Putative amidoligase enzyme UPF0121 PF03661.8 GAP92375.1 - 2.9e-07 29.9 0.1 3.9e-07 29.5 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Abhydrolase_3 PF07859.8 GAP92376.1 - 7.4e-33 113.9 0.0 1e-32 113.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 GAP92376.1 - 5.2e-11 41.9 0.0 7.6e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 GAP92376.1 - 3.8e-05 23.4 0.0 6.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP92376.1 - 0.0048 16.8 0.1 0.01 15.6 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 GAP92376.1 - 0.03 13.9 0.0 0.071 12.7 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S9 PF00326.16 GAP92376.1 - 0.075 12.2 0.0 0.22 10.7 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.13 GAP92376.1 - 0.095 11.9 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family SBF PF01758.11 GAP92378.1 - 7.5e-49 165.6 11.0 7.5e-49 165.6 7.6 2.2 3 0 0 3 3 3 1 Sodium Bile acid symporter family Med3 PF11593.3 GAP92379.1 - 5.3 6.1 6.0 5.4 6.1 4.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Cyclin_N PF00134.18 GAP92380.1 - 7.6e-09 35.2 0.0 1.5e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Palm_thioest PF02089.10 GAP92381.1 - 6e-54 182.8 0.0 7.7e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_2 PF01674.13 GAP92381.1 - 0.025 13.9 0.0 5.4 6.2 0.0 2.2 2 0 0 2 2 2 0 Lipase (class 2) DUF915 PF06028.6 GAP92381.1 - 0.034 13.2 0.0 0.053 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) HTH_18 PF12833.2 GAP92381.1 - 0.067 13.2 0.0 12 6.0 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Ribosomal_L1 PF00687.16 GAP92382.1 - 3.9e-48 163.7 0.3 3.9e-48 163.7 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family DUF2520 PF10728.4 GAP92382.1 - 0.021 14.2 0.0 0.06 12.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) ASCH PF04266.9 GAP92383.1 - 0.039 14.3 0.0 0.058 13.7 0.0 1.3 1 0 0 1 1 1 0 ASCH domain Beta-lactamase PF00144.19 GAP92384.1 - 2.2e-35 122.2 0.0 3.4e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase AAA PF00004.24 GAP92385.1 - 5.9e-18 65.3 0.0 1.3e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAP92385.1 - 0.00054 20.1 0.1 0.0036 17.4 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 GAP92385.1 - 0.00083 19.3 0.1 0.0052 16.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 GAP92385.1 - 0.007 16.1 0.0 0.095 12.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) RRN3 PF05327.6 GAP92385.1 - 0.0073 14.4 7.7 0.011 13.8 5.3 1.2 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Zot PF05707.7 GAP92385.1 - 0.0076 15.7 0.1 0.13 11.6 0.0 2.6 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_17 PF13207.1 GAP92385.1 - 0.013 16.3 2.4 0.058 14.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 GAP92385.1 - 0.037 13.7 0.1 0.1 12.3 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 GAP92385.1 - 0.05 13.5 0.0 0.27 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 GAP92385.1 - 0.06 12.1 0.6 0.21 10.3 0.0 1.9 2 0 0 2 2 2 0 ArgK protein RINGv PF12906.2 GAP92386.1 - 0.00078 19.4 5.4 0.0013 18.7 3.7 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 GAP92386.1 - 0.0038 17.0 5.7 0.0063 16.3 3.9 1.4 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 GAP92386.1 - 0.01 15.7 3.2 0.019 14.9 2.2 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 GAP92386.1 - 0.052 13.1 1.1 0.12 11.9 0.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SAPS PF04499.10 GAP92386.1 - 0.073 11.7 0.2 0.083 11.5 0.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein zf-rbx1 PF12678.2 GAP92386.1 - 0.14 12.2 1.7 0.25 11.4 1.2 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 GAP92386.1 - 0.25 11.0 3.5 0.5 10.0 2.4 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Peptidase_M28 PF04389.12 GAP92387.1 - 3.7e-35 121.2 0.0 6.5e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 GAP92387.1 - 3.2e-15 55.6 0.1 9.2e-15 54.1 0.1 1.9 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 GAP92387.1 - 0.012 15.1 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Cyclin_N PF00134.18 GAP92388.1 - 3.6e-45 152.6 0.0 5.6e-44 148.7 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 GAP92388.1 - 8.5e-34 116.0 0.0 1.7e-33 115.0 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain HABP4_PAI-RBP1 PF04774.10 GAP92388.1 - 0.075 13.5 5.2 0.19 12.2 3.6 1.7 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family Ribosomal_L2_C PF03947.13 GAP92389.1 - 8.2e-45 151.7 1.8 5.1e-44 149.2 1.3 2.1 1 1 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 GAP92389.1 - 5.5e-27 93.5 0.2 5.5e-27 93.5 0.2 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain MFS_1 PF07690.11 GAP92390.1 - 2.6e-19 69.1 54.8 7.6e-13 47.8 20.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAP92390.1 - 0.00074 18.0 33.6 0.0038 15.6 11.6 2.3 1 1 0 2 2 2 2 MFS/sugar transport protein Ligase_CoA PF00549.14 GAP92391.1 - 4.6e-33 113.9 0.8 1.6e-17 63.4 0.1 2.6 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.14 GAP92391.1 - 7.7e-16 58.3 0.3 3e-15 56.4 0.2 2.0 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.1 GAP92391.1 - 9.6e-09 34.9 0.1 5e-06 26.1 0.0 2.6 2 0 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain CHCH PF06747.8 GAP92392.1 - 7.1e-05 22.6 0.7 0.0001 22.0 0.5 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 GAP92392.1 - 0.017 15.1 2.7 0.18 11.8 2.1 1.9 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.7 GAP92392.1 - 0.28 11.0 1.8 12 5.8 0.1 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) NPR3 PF03666.8 GAP92394.1 - 1.9e-129 432.1 0.0 1.9e-129 432.1 0.0 2.1 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.6 GAP92394.1 - 0.011 14.4 0.1 0.011 14.4 0.1 1.6 2 0 0 2 2 2 0 Nitrogen permease regulator 2 Zip PF02535.17 GAP92394.1 - 0.82 8.6 2.2 1.4 7.8 1.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 GAP92394.1 - 2.4 6.0 12.6 0.44 8.5 6.4 1.4 2 0 0 2 2 2 0 CDC45-like protein Med19 PF10278.4 GAP92394.1 - 9.3 5.8 15.0 21 4.7 10.4 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 HLH PF00010.21 GAP92395.1 - 4e-12 45.6 0.0 1.1e-11 44.2 0.0 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Got1 PF04178.7 GAP92396.1 - 2.8e-30 104.8 15.4 3.7e-30 104.4 10.7 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family La PF05383.12 GAP92397.1 - 3.4e-17 61.9 0.0 5.9e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 La domain HAT PF02184.11 GAP92399.1 - 2.7e-22 78.1 77.9 1.2e-12 47.2 2.5 14.1 15 0 0 15 15 15 6 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 GAP92399.1 - 1.2e-19 69.0 21.5 0.0012 19.2 0.1 10.9 7 2 4 12 12 12 5 Tetratricopeptide repeat TPR_19 PF14559.1 GAP92399.1 - 6.5e-19 68.0 0.2 0.0003 21.0 0.0 6.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 GAP92399.1 - 1.6e-18 66.8 13.1 0.0014 19.2 0.0 8.1 9 0 0 9 9 8 4 Tetratricopeptide repeat Suf PF05843.9 GAP92399.1 - 3.2e-14 53.3 21.6 0.00096 18.9 0.6 6.3 4 2 2 6 6 6 4 Suppressor of forked protein (Suf) TPR_12 PF13424.1 GAP92399.1 - 4.5e-07 29.6 19.5 0.095 12.6 0.0 8.6 9 1 1 10 10 10 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAP92399.1 - 8.2e-07 28.4 17.8 1.8 8.6 0.1 8.3 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 GAP92399.1 - 2.3e-05 24.2 2.6 0.042 14.0 0.0 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAP92399.1 - 0.0007 19.2 5.0 24 4.9 0.3 6.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_11 PF13414.1 GAP92399.1 - 0.0033 17.0 10.9 3.8 7.2 0.0 6.0 7 2 1 8 8 7 2 TPR repeat TPR_7 PF13176.1 GAP92399.1 - 0.0068 16.1 14.9 10 6.1 0.2 7.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAP92399.1 - 0.022 14.3 3.8 53 3.6 0.4 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat U3_assoc_6 PF08640.6 GAP92399.1 - 0.036 13.8 25.0 0.19 11.5 0.8 6.9 4 2 1 6 6 6 0 U3 small nucleolar RNA-associated protein 6 Fis1_TPR_C PF14853.1 GAP92399.1 - 0.31 10.9 9.3 8.3 6.3 0.2 5.5 7 0 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat Prp31_C PF09785.4 GAP92400.1 - 1.1e-45 155.0 1.0 2.3e-45 154.0 0.7 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 GAP92400.1 - 1.1e-41 141.6 0.1 1.9e-41 140.8 0.1 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 GAP92400.1 - 1.7e-20 72.5 0.1 4.8e-20 71.1 0.0 1.8 2 0 0 2 2 2 1 NOSIC (NUC001) domain zf-C2H2_4 PF13894.1 GAP92402.1 - 3.5e-05 23.8 9.5 0.0011 19.1 0.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 GAP92402.1 - 0.00019 21.5 11.8 0.004 17.4 1.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAP92402.1 - 0.003 17.7 3.3 0.003 17.7 2.3 3.0 3 0 0 3 3 3 2 Zinc-finger double domain Integrin_B_tail PF07965.7 GAP92402.1 - 0.026 14.9 0.6 0.053 13.9 0.3 1.5 1 1 0 1 1 1 0 Integrin beta tail domain zf-met PF12874.2 GAP92402.1 - 0.15 12.3 6.8 1.3 9.2 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type CDK2AP PF09806.4 GAP92402.1 - 1.4 9.1 11.8 0.58 10.3 5.4 2.0 1 1 1 2 2 2 0 Cyclin-dependent kinase 2-associated protein adh_short_C2 PF13561.1 GAP92403.1 - 6e-31 108.0 0.0 8.7e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAP92403.1 - 2.4e-20 73.1 2.0 2.9e-20 72.8 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP92403.1 - 3.1e-06 26.9 0.4 4.9e-06 26.3 0.3 1.2 1 0 0 1 1 1 1 KR domain GST_N_3 PF13417.1 GAP92404.1 - 8.7e-22 77.1 0.0 2.3e-21 75.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAP92404.1 - 1.6e-13 50.4 0.1 5.1e-13 48.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAP92404.1 - 9.3e-06 25.7 0.8 2.3e-05 24.4 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAP92404.1 - 1.1e-05 25.2 0.4 4.8e-05 23.1 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 GAP92404.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin Fungal_trans PF04082.13 GAP92405.1 - 3.1e-21 75.4 0.0 5.4e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP92405.1 - 5.6e-10 38.9 9.5 1.2e-09 37.9 6.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 GAP92406.1 - 8.6e-36 120.5 0.4 1.1e-08 34.5 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 GAP92406.1 - 1.9e-06 26.2 0.2 0.017 13.2 0.0 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 GAP92406.1 - 1.2e-05 25.1 0.3 0.00038 20.2 0.1 2.9 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 GAP92406.1 - 0.0092 14.3 0.0 2.5 6.3 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 GAP92406.1 - 0.045 12.5 0.0 1.8 7.2 0.0 2.5 1 1 1 2 2 2 0 Nup133 N terminal like IKI3 PF04762.7 GAP92406.1 - 0.048 11.4 0.0 0.13 10.0 0.0 1.3 1 1 0 1 1 1 0 IKI3 family Coatomer_WDAD PF04053.9 GAP92406.1 - 0.065 12.0 0.0 0.23 10.1 0.0 1.7 1 1 0 1 1 1 0 Coatomer WD associated region Arena_nucleocap PF00843.12 GAP92406.1 - 0.13 10.1 0.0 0.19 9.6 0.0 1.1 1 0 0 1 1 1 0 Arenavirus nucleocapsid protein Phage_term_sma PF07141.6 GAP92406.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative bacteriophage terminase small subunit RIC1 PF07064.8 GAP92407.1 - 3.3e-89 298.7 0.1 4.5e-89 298.3 0.0 1.2 1 0 0 1 1 1 1 RIC1 WD40 PF00400.27 GAP92407.1 - 0.00011 21.9 2.5 0.66 9.9 0.1 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat CK_II_beta PF01214.13 GAP92408.1 - 4.7e-72 241.3 0.4 5.7e-72 241.0 0.3 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit PAP2 PF01569.16 GAP92409.1 - 3.1e-20 72.1 7.9 6.8e-20 71.0 2.9 2.9 3 1 0 3 3 3 1 PAP2 superfamily Rhomboid PF01694.17 GAP92409.1 - 2.5 8.1 13.5 2 8.4 0.1 3.8 4 0 0 4 4 4 0 Rhomboid family LIM PF00412.17 GAP92410.1 - 5e-14 52.1 14.7 4.2e-07 29.9 0.5 3.8 2 1 1 3 3 3 2 LIM domain Rad60-SLD PF11976.3 GAP92411.1 - 5.3e-20 70.8 0.5 6.4e-20 70.6 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 GAP92411.1 - 5.5e-10 38.5 0.3 6.6e-10 38.2 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin family HH_signal PF01085.13 GAP92411.1 - 0.11 11.9 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain Phage_Coat_B PF05356.6 GAP92412.1 - 0.084 12.5 1.1 5.3 6.8 0.1 2.7 2 0 0 2 2 2 0 Phage Coat protein B PIP5K PF01504.13 GAP92413.1 - 3.1e-85 285.3 0.0 5.2e-85 284.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase COX6B PF02297.12 GAP92414.1 - 1.1e-22 79.7 8.1 1.5e-22 79.3 5.6 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Prolamin_like PF05617.6 GAP92414.1 - 0.00095 19.2 0.4 0.0013 18.8 0.2 1.2 1 0 0 1 1 1 1 Prolamin-like Pet191_N PF10203.4 GAP92414.1 - 0.018 15.0 2.0 0.047 13.7 1.4 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 SYS1 PF09801.4 GAP92415.1 - 7.7e-35 120.0 4.1 1.2e-34 119.3 2.8 1.3 1 1 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Acyl-CoA_dh_1 PF00441.19 GAP92417.1 - 3.4e-23 82.4 0.1 5.6e-23 81.7 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAP92417.1 - 2.1e-22 79.8 0.5 4.8e-22 78.6 0.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 GAP92417.1 - 3.5e-18 64.8 0.0 9.1e-18 63.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 GAP92417.1 - 4.7e-07 30.1 0.1 8.4e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UQ_con PF00179.21 GAP92418.1 - 5.7e-51 171.6 0.0 6.4e-51 171.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAP92418.1 - 6.9e-05 22.6 0.0 7.9e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 GAP92418.1 - 0.0053 16.6 0.0 0.0057 16.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 GAP92418.1 - 0.021 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain NAD_binding_6 PF08030.7 GAP92419.1 - 7.7e-32 110.3 0.0 1.5e-31 109.4 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 GAP92419.1 - 1.5e-20 72.9 0.0 5.1e-20 71.3 0.0 1.9 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 GAP92419.1 - 2.9e-17 62.8 17.4 6.4e-17 61.8 6.0 2.3 1 1 1 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 GAP92419.1 - 0.012 15.7 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain DUF2272 PF10030.4 GAP92419.1 - 0.21 11.0 1.2 1.3 8.4 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2272) Hydrophobin_2 PF06766.6 GAP92420.1 - 8.2e-28 95.8 6.1 1.2e-27 95.3 4.2 1.3 1 0 0 1 1 1 1 Fungal hydrophobin FAA_hydrolase PF01557.13 GAP92420.1 - 8e-26 90.8 0.1 1.2e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Glyoxalase PF00903.20 GAP92421.1 - 8.2e-08 32.2 5.4 0.00015 21.7 2.7 3.0 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAP92421.1 - 2.3e-07 31.3 3.2 8.1e-05 23.1 0.1 2.7 2 1 0 2 2 2 2 Glyoxalase-like domain Fungal_trans PF04082.13 GAP92422.1 - 1.4e-20 73.3 0.0 1.9e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 GAP92422.1 - 6e-09 35.7 13.9 8.5e-05 22.6 1.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAP92422.1 - 5.2e-07 29.6 2.6 5.2e-07 29.6 1.8 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAP92422.1 - 0.00024 21.2 12.3 0.12 12.7 1.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 GAP92422.1 - 0.012 15.5 0.9 0.012 15.5 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger adh_short_C2 PF13561.1 GAP92423.1 - 4.4e-30 105.2 0.0 5e-30 105.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAP92423.1 - 1.4e-26 93.4 1.3 1.8e-26 93.0 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP92423.1 - 1.4e-13 50.9 0.3 1.8e-13 50.5 0.2 1.1 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.11 GAP92424.1 - 1.8e-34 119.0 27.1 5.6e-34 117.3 19.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily XPG_I PF00867.13 GAP92425.1 - 3.5e-30 103.9 0.1 7.6e-30 102.8 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 GAP92425.1 - 3.9e-19 68.7 0.0 1.2e-18 67.1 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 GAP92425.1 - 1.1e-05 25.6 0.2 7.2e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Myticin-prepro PF10690.4 GAP92427.1 - 0.84 9.7 7.7 1.5 8.9 5.3 1.4 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel Amidoligase_2 PF12224.3 GAP92428.1 - 4.8e-19 68.9 0.1 2.5e-14 53.5 0.0 2.3 2 1 0 2 2 2 2 Putative amidoligase enzyme Fungal_trans_2 PF11951.3 GAP92431.1 - 5.1e-15 54.9 0.3 6.1e-13 48.1 0.2 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP92431.1 - 0.00023 21.0 6.4 0.00043 20.1 4.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.17 GAP92432.1 - 7.9e-14 51.0 0.0 1.1e-12 47.4 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP92432.1 - 6e-08 32.5 0.0 1.9e-07 30.9 0.0 1.9 1 1 1 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP92432.1 - 9.7e-05 22.1 0.0 0.0003 20.5 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MMR1 PF08505.5 GAP92432.1 - 1.4 8.9 9.9 0.32 10.9 4.5 1.6 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein WD40 PF00400.27 GAP92433.1 - 4.2e-11 42.2 0.3 0.0011 18.8 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat Nbas_N PF15492.1 GAP92433.1 - 8.5e-05 21.7 0.0 0.0002 20.5 0.0 1.6 2 0 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 GAP92433.1 - 0.0041 15.0 0.0 0.01 13.6 0.0 1.5 1 1 1 2 2 2 1 IKI3 family DUF2415 PF10313.4 GAP92433.1 - 0.11 12.1 0.0 0.41 10.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) Septin PF00735.13 GAP92434.1 - 2.9e-107 357.8 0.2 6.3e-107 356.7 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 GAP92434.1 - 0.00049 20.0 0.0 0.00091 19.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 GAP92434.1 - 0.0021 17.2 0.4 0.0059 15.8 0.3 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAP92434.1 - 0.0082 16.2 0.0 0.028 14.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 GAP92434.1 - 0.017 14.9 4.2 1.4 8.7 0.0 2.9 2 1 1 3 3 3 0 Dynamin family AAA_33 PF13671.1 GAP92434.1 - 0.019 14.8 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 GAP92434.1 - 0.029 13.8 0.1 0.1 12.0 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Miro PF08477.8 GAP92434.1 - 0.039 14.4 0.4 0.1 13.0 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein AAA_17 PF13207.1 GAP92434.1 - 0.05 14.4 3.3 0.23 12.2 0.1 2.8 1 1 1 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 GAP92434.1 - 0.072 12.5 0.0 0.072 12.5 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family IIGP PF05049.8 GAP92434.1 - 0.085 11.6 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF3653 PF12375.3 GAP92434.1 - 2.7 8.2 7.5 6.6 7.0 0.3 3.3 2 1 1 3 3 3 0 Phage protein Bax1-I PF01027.15 GAP92435.1 - 8.5e-50 169.2 22.9 1e-49 168.9 15.9 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 7TMR-DISM_7TM PF07695.6 GAP92435.1 - 1.6 8.3 24.7 5.9 6.5 11.5 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling TRAM_LAG1_CLN8 PF03798.11 GAP92436.1 - 9.2e-46 155.8 22.2 9.2e-46 155.8 15.4 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 GAP92436.1 - 8.6e-18 63.6 0.1 3.3e-17 61.7 0.1 2.1 1 0 0 1 1 1 1 TRAM1-like protein DUF3611 PF12263.3 GAP92436.1 - 0.045 13.1 2.8 2.1 7.6 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3611) Glyco_transf_25 PF01755.12 GAP92439.1 - 4.3e-05 23.2 0.0 0.00032 20.4 0.0 2.3 2 1 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) ABC_tran PF00005.22 GAP92440.1 - 7.8e-49 165.4 0.1 3.9e-26 91.9 0.0 4.2 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 GAP92440.1 - 8.3e-15 55.5 3.0 3.3e-05 24.0 0.2 4.1 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 GAP92440.1 - 1.2e-11 44.2 0.3 0.0037 16.5 0.0 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 GAP92440.1 - 1.2e-07 32.2 0.7 0.0035 17.7 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 GAP92440.1 - 3.9e-07 29.4 0.5 0.015 14.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 GAP92440.1 - 1.5e-06 27.5 0.0 0.0051 16.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 GAP92440.1 - 4.2e-06 26.5 0.0 0.13 12.2 0.0 3.3 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 GAP92440.1 - 8.2e-06 25.7 0.0 0.045 13.7 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 GAP92440.1 - 1.6e-05 25.6 0.0 0.049 14.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 GAP92440.1 - 2.4e-05 24.7 0.0 0.063 13.7 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_15 PF13175.1 GAP92440.1 - 0.00014 21.0 0.0 1.2 8.0 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 GAP92440.1 - 0.00015 21.8 0.1 1.1 9.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_10 PF12846.2 GAP92440.1 - 0.00024 20.6 4.2 0.83 9.0 0.1 4.1 4 0 0 4 4 4 2 AAA-like domain MobB PF03205.9 GAP92440.1 - 0.00041 20.0 0.1 0.13 11.9 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 GAP92440.1 - 0.001 18.9 0.0 0.89 9.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 GAP92440.1 - 0.0011 18.7 0.1 0.17 11.6 0.0 3.1 2 1 0 2 2 2 1 Dynamin family NACHT PF05729.7 GAP92440.1 - 0.0015 18.2 0.1 1.4 8.5 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.1 GAP92440.1 - 0.0015 17.9 0.0 1.8 7.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 GAP92440.1 - 0.0029 17.4 1.0 0.82 9.4 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function DUF87 RNA_helicase PF00910.17 GAP92440.1 - 0.0037 17.4 0.1 3.1 8.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase ArgK PF03308.11 GAP92440.1 - 0.0039 16.0 0.8 0.64 8.7 0.1 2.6 2 0 0 2 2 2 1 ArgK protein Chromo PF00385.19 GAP92440.1 - 0.0055 16.3 3.4 0.011 15.4 1.4 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_28 PF13521.1 GAP92440.1 - 0.0087 16.0 0.0 0.2 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAP92440.1 - 0.009 16.3 0.1 0.48 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 GAP92440.1 - 0.011 15.1 0.0 1.1 8.6 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 GAP92440.1 - 0.012 15.8 0.0 3.8 7.7 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.1 GAP92440.1 - 0.012 14.1 0.0 3.6 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain HEAT_2 PF13646.1 GAP92440.1 - 0.028 14.7 1.5 2.3 8.5 0.1 3.6 2 1 0 2 2 2 0 HEAT repeats AAA_30 PF13604.1 GAP92440.1 - 0.029 13.9 1.1 5.6 6.4 0.1 3.0 3 1 0 3 3 2 0 AAA domain HEAT PF02985.17 GAP92440.1 - 0.073 13.1 1.7 1.8e+02 2.6 0.0 5.1 4 0 0 4 4 4 0 HEAT repeat DUF815 PF05673.8 GAP92440.1 - 0.088 11.7 0.1 2.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF3584 PF12128.3 GAP92440.1 - 0.14 9.4 1.1 2.7 5.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Apc5 PF12862.2 GAP92441.1 - 2.5e-34 116.9 5.1 2.5e-34 116.9 3.5 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 GAP92441.1 - 0.0015 18.4 6.8 3.2 7.7 0.0 5.6 6 2 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAP92441.1 - 0.0034 16.9 1.4 13 5.5 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAP92441.1 - 0.0096 15.6 1.5 1.8 8.5 0.0 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAP92441.1 - 0.15 12.8 14.1 1.1 10.0 0.0 6.8 7 1 1 8 8 8 0 Tetratricopeptide repeat CIA30 PF08547.7 GAP92442.1 - 7.1e-44 149.4 0.0 9e-44 149.0 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) DUF1681 PF07933.9 GAP92442.1 - 0.059 12.9 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1681) ANTH PF07651.11 GAP92443.1 - 2.5e-79 265.9 0.0 2.5e-79 265.9 0.0 2.5 2 1 1 3 3 3 1 ANTH domain I_LWEQ PF01608.12 GAP92443.1 - 3.3e-64 215.4 8.1 3.3e-64 215.4 5.6 4.9 4 2 0 5 5 5 1 I/LWEQ domain ENTH PF01417.15 GAP92443.1 - 0.00077 19.3 0.0 0.0037 17.1 0.0 2.2 1 0 0 1 1 1 1 ENTH domain COX6A PF02046.10 GAP92444.1 - 1.3e-47 160.5 1.7 1.5e-47 160.3 1.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Chal_sti_synt_N PF00195.14 GAP92444.1 - 0.12 11.5 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain Exo_endo_phos_2 PF14529.1 GAP92445.1 - 8.9e-16 57.5 0.0 2.4e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 GAP92445.1 - 1.7e-14 54.3 0.0 3e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.7 GAP92445.1 - 7.3e-07 29.0 0.4 1.8e-06 27.7 0.3 1.7 1 0 0 1 1 1 1 GRF zinc finger MFS_1 PF07690.11 GAP92446.1 - 1.5e-31 109.3 37.8 1.5e-31 109.3 26.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP92446.1 - 1.9e-08 33.3 8.4 1.9e-08 33.3 5.8 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter Peroxidase_2 PF01328.12 GAP92448.1 - 3.5e-34 117.9 0.1 4.4e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Collar PF07484.7 GAP92448.1 - 0.017 14.8 0.0 5.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Phage Tail Collar Domain MFS_1 PF07690.11 GAP92449.1 - 1.8e-37 128.9 20.6 1.8e-37 128.9 14.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP92449.1 - 9.5e-07 27.7 6.4 1.7e-06 26.9 4.4 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 GAP92449.1 - 0.00015 20.3 4.6 0.00015 20.3 3.2 2.4 2 1 1 3 3 3 1 MFS/sugar transport protein TRI12 PF06609.8 GAP92449.1 - 0.0017 16.6 1.0 0.0025 16.0 0.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 GAP92449.1 - 0.012 15.3 1.5 0.56 10.0 0.0 3.1 2 0 0 2 2 2 0 MFS_1 like family Cutinase PF01083.17 GAP92450.1 - 4.2e-38 130.8 0.8 4.9e-38 130.6 0.5 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 GAP92450.1 - 0.0021 17.5 0.1 0.0028 17.1 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.15 GAP92450.1 - 0.049 13.1 0.0 0.066 12.7 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 GAP92450.1 - 0.095 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Zn_clus PF00172.13 GAP92451.1 - 4.2e-11 42.5 11.2 8.5e-11 41.5 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAP92451.1 - 0.00015 20.5 0.6 0.00019 20.1 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain EndIII_4Fe-2S PF10576.4 GAP92451.1 - 2.1 8.6 6.0 4.9 7.5 0.5 2.5 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III H_lectin PF09458.5 GAP92452.1 - 8.3e-09 34.9 0.1 1.5e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 H-type lectin domain MMR_HSR1 PF01926.18 GAP92453.1 - 2.4e-08 33.9 0.0 4.6e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 GAP92453.1 - 1e-07 31.2 0.1 2.9e-07 29.8 0.0 1.6 1 1 1 2 2 2 1 AIG1 family Dynamin_N PF00350.18 GAP92453.1 - 3.3e-05 23.7 0.4 0.025 14.4 0.0 2.9 2 1 1 3 3 3 1 Dynamin family DUF258 PF03193.11 GAP92453.1 - 0.00018 20.7 0.0 0.00038 19.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 GAP92453.1 - 0.00029 19.9 0.0 0.00062 18.8 0.0 1.6 1 0 0 1 1 1 1 Septin Miro PF08477.8 GAP92453.1 - 0.00057 20.3 0.0 0.0012 19.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 GAP92453.1 - 0.0011 19.1 0.0 0.0035 17.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain FeoB_N PF02421.13 GAP92453.1 - 0.0058 15.9 0.1 0.015 14.6 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B FtsK_SpoIIIE PF01580.13 GAP92453.1 - 0.0073 15.7 1.4 0.068 12.6 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family T2SE PF00437.15 GAP92453.1 - 0.0083 15.0 0.2 0.018 13.9 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_28 PF13521.1 GAP92453.1 - 0.013 15.5 2.1 0.09 12.7 0.1 3.1 2 2 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 GAP92453.1 - 0.019 14.5 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase GTP_EFTU PF00009.22 GAP92453.1 - 0.02 14.3 0.6 0.2 11.0 0.4 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 GAP92453.1 - 0.024 14.9 0.0 0.057 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 GAP92453.1 - 0.026 14.5 0.0 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 GAP92453.1 - 0.044 14.0 0.0 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.1 GAP92453.1 - 0.046 13.5 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 GAP92453.1 - 0.047 12.9 0.2 0.2 10.8 0.0 2.1 2 1 1 3 3 3 0 Signal recognition particle receptor beta subunit KaiC PF06745.8 GAP92453.1 - 0.062 12.4 1.1 5.8 5.9 0.3 2.3 2 0 0 2 2 2 0 KaiC MobB PF03205.9 GAP92453.1 - 0.095 12.4 0.2 0.23 11.1 0.1 1.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 GAP92453.1 - 0.13 11.8 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 GAP92453.1 - 0.13 13.0 1.5 0.54 11.0 0.1 2.2 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 GAP92453.1 - 0.23 10.9 2.9 3 7.3 0.1 2.9 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein RicinB_lectin_2 PF14200.1 GAP92455.1 - 4.1e-13 49.6 4.8 1.5e-11 44.5 2.5 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like ABC_cobalt PF09819.4 GAP92456.1 - 0.16 11.9 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 ABC-type cobalt transport system, permease component ETF_QO PF05187.8 GAP92457.1 - 2.3e-45 153.0 0.0 3.6e-45 152.4 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 GAP92457.1 - 9.9e-09 34.5 0.4 7.5e-05 21.7 0.1 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAP92457.1 - 1.5e-07 31.3 0.0 4e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAP92457.1 - 3.2e-05 22.9 0.3 0.0034 16.2 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 GAP92457.1 - 6.8e-05 22.8 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAP92457.1 - 7.5e-05 21.9 0.0 0.00012 21.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAP92457.1 - 9.6e-05 21.0 0.3 0.00014 20.4 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 GAP92457.1 - 0.00032 19.4 0.0 0.16 10.5 0.0 2.2 1 1 1 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.1 GAP92457.1 - 0.00071 19.3 0.2 0.0036 17.0 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 GAP92457.1 - 0.00091 18.3 0.2 0.0022 17.1 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 GAP92457.1 - 0.0014 19.0 0.0 2.9 8.3 0.0 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAP92457.1 - 0.0014 17.7 0.0 0.0099 14.9 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 GAP92457.1 - 0.0015 18.6 0.0 0.0025 17.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.2 GAP92457.1 - 0.0076 16.6 0.7 0.024 15.0 0.5 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Lycopene_cycl PF05834.7 GAP92457.1 - 0.015 14.2 0.1 0.024 13.5 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Internalin_N PF12354.3 GAP92457.1 - 0.058 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial adhesion/invasion protein N terminal GIDA PF01134.17 GAP92457.1 - 0.074 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Med15 PF09606.5 GAP92458.1 - 0.47 8.6 84.2 0.59 8.2 58.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AMP-binding PF00501.23 GAP92459.1 - 1.8e-79 267.0 0.0 3.4e-79 266.1 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 GAP92459.1 - 4.7e-58 196.0 0.4 4.8e-57 192.7 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 GAP92459.1 - 4.5e-38 130.7 12.0 1.1e-35 123.0 5.5 2.9 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 GAP92459.1 - 4.5e-23 81.8 9.2 1.1e-19 70.7 3.7 2.5 2 0 0 2 2 2 2 KR domain Epimerase PF01370.16 GAP92459.1 - 1.7e-19 70.1 0.6 1.3e-09 37.8 0.0 3.1 3 1 0 3 3 3 2 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 GAP92459.1 - 4.4e-17 62.6 0.3 8.6e-17 61.7 0.2 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.20 GAP92459.1 - 1.1e-08 35.2 0.0 3.2e-08 33.6 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 GAP92459.1 - 2e-08 33.4 2.0 0.00033 19.6 0.0 3.2 3 0 0 3 3 3 2 RmlD substrate binding domain AMP-binding_C PF13193.1 GAP92459.1 - 2e-07 31.8 1.6 5.3e-06 27.2 0.6 3.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 GAP92459.1 - 2.5e-07 29.6 0.5 0.0029 16.3 0.0 3.0 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAP92459.1 - 2.9e-06 27.4 6.4 2.2e-05 24.5 2.4 3.2 3 0 0 3 3 3 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 GAP92459.1 - 3.7e-06 26.0 4.9 0.00056 18.9 0.1 3.2 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.14 GAP92459.1 - 0.00024 20.2 0.1 0.00061 18.8 0.1 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Saccharop_dh PF03435.13 GAP92459.1 - 0.0023 16.9 0.4 0.0041 16.1 0.3 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 GAP92459.1 - 0.0036 16.6 2.2 0.31 10.2 0.6 2.8 3 0 0 3 3 3 1 NmrA-like family DFP PF04127.10 GAP92459.1 - 0.0043 16.6 3.2 0.0053 16.3 1.2 1.8 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Eno-Rase_NADH_b PF12242.3 GAP92459.1 - 0.01 15.5 1.0 0.03 14.1 0.7 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ApbA PF02558.11 GAP92459.1 - 0.013 14.8 1.2 0.029 13.8 0.1 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 GAP92459.1 - 0.066 12.8 0.9 0.14 11.8 0.6 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 GAP92459.1 - 0.073 13.5 1.5 1.3 9.4 0.2 2.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TBP PF00352.16 GAP92460.1 - 2.5e-70 231.8 0.1 4.2e-35 118.9 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 GAP92460.1 - 0.00019 21.4 0.0 0.81 9.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Pollen_allerg_2 PF01620.11 GAP92460.1 - 0.0032 17.7 1.1 0.0041 17.4 0.8 1.3 1 0 0 1 1 1 1 Ribonuclease (pollen allergen) Nup_retrotrp_bd PF10599.4 GAP92460.1 - 2.1 9.0 6.3 0.93 10.1 2.5 1.7 2 1 0 2 2 2 0 Retro-transposon transporting motif DAO PF01266.19 GAP92461.1 - 2.9e-46 158.0 2.3 4e-46 157.5 1.6 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAP92461.1 - 7.1e-06 25.8 0.0 0.012 15.4 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 GAP92461.1 - 0.00035 20.5 0.0 0.92 9.3 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP92461.1 - 0.00079 19.4 1.8 0.002 18.0 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 GAP92461.1 - 0.058 12.3 0.0 0.091 11.6 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 GAP92461.1 - 0.14 12.5 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Dicty_REP PF05086.7 GAP92461.1 - 0.24 9.1 1.7 0.43 8.2 1.2 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Surp PF01805.15 GAP92462.1 - 9.4e-18 63.6 0.0 1.6e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Surp module TAF4 PF05236.9 GAP92462.1 - 0.24 10.6 1.6 0.42 9.8 1.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family PNRC PF15365.1 GAP92463.1 - 0.054 13.4 4.3 0.22 11.5 0.3 2.9 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator Clr5 PF14420.1 GAP92465.1 - 0.0003 20.6 2.9 0.00057 19.7 2.0 1.5 1 0 0 1 1 1 1 Clr5 domain DAO PF01266.19 GAP92466.1 - 2.4e-48 164.8 7.2 6.8e-37 127.1 5.9 2.0 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAP92466.1 - 3.1e-07 30.6 0.0 0.0069 16.7 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP92466.1 - 7.2e-06 25.9 0.0 2.1e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 GAP92466.1 - 0.00011 20.9 0.0 0.015 13.9 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.9 GAP92466.1 - 0.0014 18.5 0.0 0.0037 17.1 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAP92466.1 - 0.0014 18.4 0.0 0.073 12.8 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding GMC_oxred_N PF00732.14 GAP92466.1 - 0.0043 16.2 0.0 1.8 7.6 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase FAD_oxidored PF12831.2 GAP92466.1 - 0.018 14.1 2.2 0.032 13.2 0.0 2.0 2 1 0 2 2 2 0 FAD dependent oxidoreductase Amino_oxidase PF01593.19 GAP92466.1 - 0.025 13.6 0.0 0.069 12.2 0.1 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Saccharop_dh PF03435.13 GAP92466.1 - 0.049 12.6 0.0 0.091 11.7 0.0 1.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase Thi4 PF01946.12 GAP92466.1 - 0.063 12.3 0.0 0.77 8.8 0.0 2.2 2 0 0 2 2 2 0 Thi4 family PhyH PF05721.8 GAP92468.1 - 0.0019 18.2 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Pectate_lyase_3 PF12708.2 GAP92470.1 - 2e-85 286.5 25.9 2e-69 234.1 6.1 3.6 3 1 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 GAP92470.1 - 4e-08 32.6 2.0 0.0042 16.5 0.2 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Herpes_UL42 PF02282.11 GAP92470.1 - 0.11 12.0 0.1 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase processivity factor (UL42) Fungal_trans PF04082.13 GAP92471.1 - 1.3e-11 43.9 1.9 3e-11 42.7 1.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 GAP92471.1 - 1.5e-08 34.4 7.5 0.0018 18.5 0.1 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP92471.1 - 3.8e-06 26.8 10.2 0.0046 17.1 2.2 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAP92471.1 - 6.9e-06 26.1 14.7 5.6e-05 23.2 1.1 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 GAP92471.1 - 0.039 14.1 0.8 0.67 10.1 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 GAP92471.1 - 0.08 12.8 1.0 10 6.1 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2461 PF09365.5 GAP92472.1 - 1.7e-72 243.2 0.0 2.3e-72 242.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Pox_Ag35 PF03286.9 GAP92472.1 - 0.79 9.2 34.1 0.066 12.7 3.2 3.3 3 0 0 3 3 3 0 Pox virus Ag35 surface protein NOA36 PF06524.7 GAP92472.1 - 6.3 5.9 44.7 0.72 9.0 9.2 3.5 3 0 0 3 3 3 0 NOA36 protein Glyco_hydro_92 PF07971.7 GAP92473.1 - 6.2e-169 562.8 0.0 7.5e-169 562.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 DUF1237 PF06824.6 GAP92474.1 - 9.5e-176 584.5 0.0 1.1e-175 584.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) ATG13 PF10033.4 GAP92475.1 - 1.6e-66 224.0 0.0 3.5e-66 222.9 0.0 1.6 2 0 0 2 2 2 1 Autophagy-related protein 13 VHS PF00790.14 GAP92476.1 - 6.8e-35 119.7 0.0 1.7e-34 118.4 0.0 1.6 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.1 GAP92476.1 - 3.4e-17 61.7 0.2 7.3e-17 60.6 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAP92476.1 - 2.2e-16 58.9 0.0 5.2e-16 57.7 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAP92476.1 - 9.4e-14 50.6 0.1 2.1e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.9 GAP92476.1 - 0.0096 15.8 0.7 0.031 14.2 0.5 1.8 1 0 0 1 1 1 1 GAT domain DUF4510 PF14971.1 GAP92476.1 - 0.023 14.8 0.4 0.057 13.5 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) UIM PF02809.15 GAP92476.1 - 0.15 11.6 4.2 0.39 10.4 2.9 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif TIR PF01582.15 GAP92476.1 - 0.23 10.9 2.0 0.18 11.2 0.2 1.6 2 0 0 2 2 2 0 TIR domain Clr5 PF14420.1 GAP92477.1 - 1.1e-20 73.1 0.7 1.1e-20 73.1 0.5 1.8 2 0 0 2 2 2 1 Clr5 domain SNF2_N PF00176.18 GAP92478.1 - 1.1e-72 244.3 0.1 3e-72 242.9 0.1 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAP92478.1 - 5.4e-11 42.1 0.0 1.2e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD_2 PF06733.10 GAP92478.1 - 0.0014 18.0 0.2 0.0041 16.5 0.0 1.8 2 0 0 2 2 2 1 DEAD_2 HDA2-3 PF11496.3 GAP92478.1 - 0.01 14.6 0.1 0.17 10.7 0.0 2.5 2 1 1 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 NMO PF03060.10 GAP92479.1 - 1.5e-68 231.3 0.6 2.6e-68 230.5 0.4 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 GAP92479.1 - 1e-12 47.6 0.0 2.1e-05 23.5 0.3 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 GAP92479.1 - 4.2e-05 22.5 0.2 7.1e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 GAP92479.1 - 0.012 14.8 0.0 0.034 13.4 0.0 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein Glu_synthase PF01645.12 GAP92479.1 - 0.014 14.3 0.7 0.044 12.6 0.5 1.8 1 1 0 1 1 1 0 Conserved region in glutamate synthase TMP-TENI PF02581.12 GAP92479.1 - 0.029 13.5 0.2 0.053 12.6 0.1 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI DUF1902 PF08972.6 GAP92479.1 - 0.048 13.2 0.0 0.17 11.4 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1902) NanE PF04131.9 GAP92479.1 - 0.062 12.2 0.1 0.1 11.5 0.1 1.5 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase SelR PF01641.13 GAP92480.1 - 8e-49 164.4 0.1 1e-48 164.1 0.1 1.1 1 0 0 1 1 1 1 SelR domain DZR PF12773.2 GAP92480.1 - 0.063 13.1 1.2 5.2 6.9 0.2 2.3 2 0 0 2 2 2 0 Double zinc ribbon DUF2296 PF10058.4 GAP92480.1 - 0.095 12.4 0.2 0.91 9.3 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Yippee-Mis18 PF03226.9 GAP92480.1 - 0.16 12.0 0.4 0.55 10.3 0.3 1.8 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C2H2_2 PF12756.2 GAP92481.1 - 3.4e-30 104.1 25.3 8.3e-29 99.6 1.8 3.8 4 0 0 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 GAP92481.1 - 1.5e-05 25.0 1.3 1.5e-05 25.0 0.9 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 GAP92481.1 - 2.3e-05 24.3 24.8 5.9e-05 23.0 1.0 4.2 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 GAP92481.1 - 0.0095 16.2 10.6 0.16 12.3 0.4 4.8 4 0 0 4 4 4 1 C2H2-type zinc finger zf-DBF PF07535.7 GAP92481.1 - 0.063 12.9 0.4 0.063 12.9 0.2 4.2 5 0 0 5 5 5 0 DBF zinc finger SnoaL_2 PF12680.2 GAP92481.1 - 0.065 13.6 0.2 1.5 9.3 0.1 2.5 2 0 0 2 2 2 0 SnoaL-like domain DUF629 PF04780.7 GAP92481.1 - 0.13 10.7 0.4 0.33 9.4 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2 PF00096.21 GAP92481.1 - 0.89 10.0 19.8 1.6 9.2 0.3 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 GAP92481.1 - 6.7 6.7 10.8 9.8 6.2 0.1 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger HECT PF00632.20 GAP92482.1 - 2.4e-70 237.2 0.0 4e-70 236.4 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Cpn60_TCP1 PF00118.19 GAP92483.1 - 8.2e-147 489.7 1.8 9.3e-147 489.5 1.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AMP-binding PF00501.23 GAP92484.1 - 1.1e-78 264.5 0.0 1.4e-78 264.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme UCH PF00443.24 GAP92485.1 - 3.1e-33 115.0 0.0 4.9e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAP92485.1 - 1e-16 61.2 0.0 1.5e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 GAP92485.1 - 0.0041 17.4 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Peptidase_C98 PF15499.1 GAP92485.1 - 0.16 11.2 0.1 0.97 8.6 0.0 2.2 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase VHS PF00790.14 GAP92486.1 - 8.6e-41 138.8 1.7 1.2e-39 135.1 0.0 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 GAP92486.1 - 3e-15 55.8 5.3 5.4e-15 55.0 3.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 GAP92486.1 - 3.7e-06 26.0 8.5 0.0091 15.4 0.5 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif zf-DHHC PF01529.15 GAP92486.1 - 0.0014 18.0 1.3 0.0014 18.0 0.9 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase GTP_EFTU PF00009.22 GAP92487.1 - 3e-47 160.4 0.0 5.7e-47 159.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 GAP92487.1 - 3.4e-21 75.1 0.9 6.7e-21 74.1 0.6 1.5 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.18 GAP92487.1 - 6.3e-08 32.5 0.1 1.2e-06 28.4 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 GAP92487.1 - 1.2e-07 31.6 0.2 6.2e-07 29.4 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.12 GAP92487.1 - 2.3e-07 30.9 0.1 2.8e-06 27.4 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain Miro PF08477.8 GAP92487.1 - 7e-06 26.5 0.7 0.0025 18.2 0.0 3.0 3 0 0 3 3 3 1 Miro-like protein GTP_EFTU_D4 PF14578.1 GAP92487.1 - 0.0024 17.4 0.0 0.0058 16.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 SRPRB PF09439.5 GAP92487.1 - 0.0039 16.4 0.1 0.16 11.1 0.0 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 GAP92487.1 - 0.037 13.4 0.2 0.58 9.5 0.0 2.6 3 0 0 3 3 3 0 Ras family FeoB_N PF02421.13 GAP92487.1 - 0.1 11.8 0.0 1.8 7.8 0.0 2.7 2 1 0 2 2 2 0 Ferrous iron transport protein B HSP70 PF00012.15 GAP92488.1 - 1.2e-267 888.7 10.6 1.3e-267 888.6 7.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAP92488.1 - 4.7e-19 68.1 0.2 6.3e-17 61.1 0.0 2.2 1 1 1 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.13 GAP92488.1 - 0.0053 15.8 4.0 0.034 13.2 0.1 3.0 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase Radial_spoke_3 PF06098.6 GAP92488.1 - 0.01 14.8 1.2 0.01 14.8 0.8 1.7 2 0 0 2 2 2 0 Radial spoke protein 3 FtsA PF14450.1 GAP92488.1 - 0.027 14.3 2.4 3.5 7.5 0.0 3.7 3 1 0 3 3 3 0 Cell division protein FtsA Sugar_tr PF00083.19 GAP92489.1 - 2.1e-32 112.2 35.2 3.2e-18 65.5 8.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAP92489.1 - 8e-23 80.7 43.6 3.6e-13 48.9 15.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DEAD PF00270.24 GAP92491.1 - 4.1e-09 36.1 0.0 8.4e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP92491.1 - 1.1e-07 31.5 0.0 7.7e-07 28.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain T4SS-DNA_transf PF02534.9 GAP92491.1 - 0.0025 16.4 0.0 0.0038 15.8 0.0 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer DUF4403 PF14356.1 GAP92492.1 - 0.28 9.4 5.2 0.53 8.5 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4403) OMP_b-brl_2 PF13568.1 GAP92492.1 - 0.37 10.5 4.0 4.9 6.9 1.3 2.4 2 1 0 2 2 2 0 Outer membrane protein beta-barrel domain YadA_anchor PF03895.10 GAP92492.1 - 8.1 6.5 7.6 4.2 7.4 1.3 2.4 2 0 0 2 2 2 0 YadA-like C-terminal region PT PF04886.7 GAP92493.1 - 0.017 14.4 40.6 0.12 11.6 6.0 4.1 2 1 0 2 2 2 0 PT repeat Pkinase PF00069.20 GAP92494.1 - 7e-41 140.0 0.0 1.3e-40 139.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP92494.1 - 9.5e-19 67.4 0.0 1.5e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 GAP92494.1 - 1.4e-06 28.3 0.6 4.2e-06 26.7 0.1 2.1 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 GAP92494.1 - 0.19 10.6 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like zf-C3H1 PF10650.4 GAP92495.1 - 0.011 15.2 0.4 0.02 14.3 0.3 1.4 1 0 0 1 1 1 0 Putative zinc-finger domain Pkinase PF00069.20 GAP92496.1 - 1.3e-12 47.4 0.0 3.6e-11 42.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP92496.1 - 0.00095 18.3 0.6 0.021 13.8 0.4 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 GAP92496.1 - 0.0028 16.7 0.2 0.015 14.3 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAP92496.1 - 0.0098 15.6 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.6 GAP92496.1 - 0.074 12.2 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) FAD_binding_4 PF01565.18 GAP92497.1 - 6.3e-19 67.8 0.3 1.1e-18 67.0 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP92497.1 - 0.063 13.2 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like NAD_binding_10 PF13460.1 GAP92498.1 - 0.00093 19.2 0.0 0.0024 17.8 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 GAP92498.1 - 0.073 12.4 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family SKG6 PF08693.5 GAP92499.1 - 0.24 10.7 6.2 0.19 11.0 2.5 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Fungal_trans PF04082.13 GAP92500.1 - 4.7e-14 51.8 0.1 8e-14 51.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP92500.1 - 4.8e-06 26.3 13.6 1.3e-05 24.9 9.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1765 PF08578.5 GAP92501.1 - 0.074 13.1 0.2 0.15 12.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1765) DUF2404 PF10296.4 GAP92502.1 - 3.4e-31 107.2 0.1 7.8e-31 106.0 0.0 1.6 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 GAP92502.1 - 0.0049 17.0 0.1 0.03 14.5 0.0 2.4 3 1 0 3 3 3 1 PH domain DNA_pol_B PF00136.16 GAP92503.1 - 9.5e-98 327.9 0.0 1.4e-97 327.4 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 GAP92503.1 - 6.3e-20 71.2 0.0 5.6e-09 35.2 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 GAP92503.1 - 6.5e-18 64.5 2.3 1.5e-17 63.3 1.6 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DZR PF12773.2 GAP92503.1 - 1.4 8.8 4.1 3.2 7.6 2.8 1.6 1 0 0 1 1 1 0 Double zinc ribbon Slu7 PF11708.3 GAP92504.1 - 3.9e-77 259.2 14.0 3.9e-77 259.2 9.7 2.2 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 GAP92504.1 - 0.022 14.4 0.7 0.042 13.5 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Ribosomal_S4 PF00163.14 GAP92505.1 - 6.2e-29 100.2 1.0 1.4e-28 99.0 0.7 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 GAP92505.1 - 4.2e-13 48.4 1.2 4.2e-13 48.4 0.8 2.5 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 GAP92506.1 - 1.1e-39 134.2 4.9 1.4e-39 133.8 2.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L21e DUF3900 PF13039.1 GAP92506.1 - 0.074 12.5 0.0 0.094 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3900) p450 PF00067.17 GAP92508.1 - 1.9e-61 207.9 0.0 2.7e-61 207.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 GAP92509.1 - 2.2e-07 30.6 10.6 2.2e-07 30.6 7.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1265 PF06887.9 GAP92509.1 - 0.071 12.7 0.2 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1265) Sugar_tr PF00083.19 GAP92511.1 - 2.5e-98 329.5 33.6 2.9e-98 329.3 23.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP92511.1 - 1.6e-24 86.2 33.8 1.6e-24 86.2 23.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily GFO_IDH_MocA PF01408.17 GAP92512.1 - 6.9e-24 84.6 1.0 1.4e-23 83.6 0.5 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 GAP92512.1 - 8.6e-08 32.1 0.0 2.7e-06 27.3 0.0 2.3 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA_C PF02894.12 GAP92512.1 - 9.5e-07 28.6 0.1 2.5e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_7 PF13241.1 GAP92512.1 - 0.00037 20.6 0.1 0.00078 19.6 0.1 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_2 PF03446.10 GAP92512.1 - 0.048 13.4 0.1 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Gp_dh_N PF00044.19 GAP92512.1 - 0.06 13.3 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain CoA_binding PF02629.14 GAP92512.1 - 0.11 13.0 0.1 0.24 11.9 0.1 1.6 1 0 0 1 1 1 0 CoA binding domain SUR7 PF06687.7 GAP92513.1 - 3.9e-29 101.7 14.6 5e-29 101.3 10.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family NfeD PF01957.13 GAP92513.1 - 0.0034 17.5 3.0 0.0034 17.5 2.1 2.3 2 1 0 2 2 2 1 NfeD-like C-terminal, partner-binding MFS_2 PF13347.1 GAP92513.1 - 0.015 13.7 3.5 0.016 13.5 0.8 1.9 2 0 0 2 2 2 0 MFS/sugar transport protein DUF4579 PF15158.1 GAP92513.1 - 0.13 11.7 0.5 0.2 11.1 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4579) CobD_Cbib PF03186.8 GAP92513.1 - 0.18 10.8 3.0 0.34 9.9 2.1 1.4 1 0 0 1 1 1 0 CobD/Cbib protein Tetraspannin PF00335.15 GAP92513.1 - 1.6 7.9 5.6 5.5 6.2 4.1 1.6 1 1 0 1 1 1 0 Tetraspanin family DUF4381 PF14316.1 GAP92513.1 - 5.6 7.0 7.0 0.18 11.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) ABC1 PF03109.11 GAP92514.1 - 4.9e-22 78.1 0.0 1.1e-21 77.0 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 GAP92514.1 - 9.8e-06 25.4 0.0 2.6e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Septin PF00735.13 GAP92515.1 - 1.2e-30 106.5 0.0 1.7e-09 37.1 0.0 3.1 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.13 GAP92515.1 - 0.0016 17.9 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Miro PF08477.8 GAP92515.1 - 0.01 16.3 0.0 0.025 15.0 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_16 PF13191.1 GAP92515.1 - 0.01 15.8 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 GAP92515.1 - 0.014 16.2 0.3 0.06 14.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.15 GAP92515.1 - 0.016 13.8 0.0 0.029 13.0 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit KAP_NTPase PF07693.9 GAP92515.1 - 0.045 12.7 0.0 0.052 12.5 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_23 PF13476.1 GAP92515.1 - 0.054 13.8 0.1 0.083 13.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 GAP92515.1 - 0.094 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 GAP92515.1 - 0.1 11.9 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein Dynamin_N PF00350.18 GAP92515.1 - 0.33 10.7 2.0 0.85 9.4 0.1 2.3 2 1 1 3 3 3 0 Dynamin family Nop14 PF04147.7 GAP92515.1 - 0.87 7.4 9.6 1.2 6.9 6.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1996 PF09362.5 GAP92516.1 - 1.2e-85 286.9 1.3 1.5e-85 286.6 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Caps_synth PF05704.7 GAP92517.1 - 3.2e-09 36.3 0.0 7.2e-09 35.2 0.0 1.5 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 GAP92517.1 - 1.4e-05 25.3 0.0 2.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Abhydrolase_3 PF07859.8 GAP92518.1 - 8e-56 188.9 0.6 1.2e-55 188.3 0.4 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 GAP92518.1 - 5.3e-09 35.3 0.9 2.7e-08 33.0 0.6 1.8 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 GAP92518.1 - 0.00092 18.4 0.0 0.012 14.8 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAP92518.1 - 0.0022 17.7 0.1 0.0033 17.1 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP92518.1 - 0.025 14.1 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.3 GAP92518.1 - 0.065 12.5 0.5 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Kelch_5 PF13854.1 GAP92518.1 - 0.14 12.1 1.6 2.4 8.1 0.3 2.8 2 1 0 2 2 2 0 Kelch motif AXE1 PF05448.7 GAP92518.1 - 0.17 10.3 0.1 0.26 9.7 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Ank_2 PF12796.2 GAP92519.1 - 2.8e-08 33.9 0.0 0.0031 17.8 0.0 3.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAP92519.1 - 6.6e-08 31.9 0.6 0.15 11.9 0.0 4.9 5 1 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 GAP92519.1 - 3.7e-05 24.1 0.0 2 9.0 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP92519.1 - 0.00094 19.2 0.1 12 6.4 0.0 5.6 6 1 0 6 6 6 1 Ankyrin repeat F-box-like PF12937.2 GAP92519.1 - 0.049 13.3 0.0 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 F-box-like Zn_clus PF00172.13 GAP92520.1 - 3.5e-08 33.2 11.9 3.5e-08 33.2 8.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lin-8 PF03353.10 GAP92520.1 - 6.1 6.0 6.2 0.3 10.3 0.5 1.5 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist 4HBT_3 PF13622.1 GAP92521.1 - 2.3e-38 132.4 5.0 3.7e-38 131.7 3.4 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 GAP92521.1 - 1e-16 60.7 0.0 0.0003 20.4 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase Oxysterol_BP PF01237.13 GAP92522.1 - 1.1e-123 412.2 0.0 3.9e-123 410.4 0.0 1.8 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 GAP92522.1 - 5.2e-19 68.3 0.0 1e-12 48.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAP92522.1 - 8.9e-17 60.7 0.2 7.2e-10 38.7 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 GAP92522.1 - 1.5e-16 59.2 0.0 4.5e-05 23.0 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 GAP92522.1 - 1.6e-15 55.6 0.0 0.00076 19.4 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 GAP92522.1 - 2.5e-15 56.4 0.1 1.7e-08 34.7 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PH PF00169.24 GAP92522.1 - 4e-12 46.2 0.3 7.4e-12 45.3 0.2 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAP92522.1 - 3.8e-10 40.0 0.9 9.3e-10 38.7 0.7 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 GAP92522.1 - 2.3e-08 34.0 0.9 5.4e-08 32.8 0.6 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Peptidase_A22B PF04258.8 GAP92524.1 - 6.5e-47 160.4 3.8 3.5e-46 158.0 2.6 2.0 1 1 0 1 1 1 1 Signal peptide peptidase Presenilin PF01080.12 GAP92524.1 - 1.4 7.6 6.1 6.2 5.5 0.2 2.4 2 0 0 2 2 2 0 Presenilin Pro_isomerase PF00160.16 GAP92525.1 - 4.1e-48 163.4 0.0 4.7e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TraT PF05818.7 GAP92526.1 - 0.13 11.6 1.9 0.52 9.7 0.1 2.1 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein Sgf11 PF08209.6 GAP92526.1 - 0.78 9.1 7.6 0.16 11.3 1.8 2.0 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Acetyltransf_1 PF00583.19 GAP92527.1 - 4.5e-09 36.2 0.0 8.1e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAP92527.1 - 0.0032 17.5 0.0 0.0085 16.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAP92527.1 - 0.077 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HET PF06985.6 GAP92528.1 - 6.4e-22 78.2 0.2 1.1e-21 77.4 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SET PF00856.23 GAP92529.1 - 2.2e-20 73.6 0.1 1.5e-19 70.8 0.0 2.3 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.11 GAP92529.1 - 2.2e-17 63.2 4.7 2.2e-17 63.2 3.2 2.1 2 0 0 2 2 2 1 Pre-SET motif Lipoxygenase PF00305.14 GAP92530.1 - 4.8e-28 97.5 0.0 6.6e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 Lipoxygenase Adenylsucc_synt PF00709.16 GAP92531.1 - 5.9e-150 499.5 0.0 6.7e-150 499.4 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Cor1 PF04803.7 GAP92531.1 - 0.11 12.2 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region Nop52 PF05997.7 GAP92532.1 - 2.6e-42 144.7 0.0 5.6e-39 133.8 0.0 2.1 2 0 0 2 2 2 2 Nucleolar protein,Nop52 Nucleoplasmin PF03066.10 GAP92532.1 - 0.84 9.1 4.4 4.5 6.7 0.3 2.2 2 0 0 2 2 2 0 Nucleoplasmin DUF4611 PF15387.1 GAP92532.1 - 1.5 8.9 10.1 4.5 7.4 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Nop14 PF04147.7 GAP92532.1 - 1.6 6.5 3.3 3.9 5.2 2.3 1.4 1 1 0 1 1 1 0 Nop14-like family CobT PF06213.7 GAP92532.1 - 3.5 6.6 10.4 4.8 6.2 0.1 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DAGK_cat PF00781.19 GAP92533.1 - 1.3e-24 86.0 0.2 2.2e-24 85.3 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain 4HBT_3 PF13622.1 GAP92534.1 - 7e-54 183.2 3.5 8.2e-54 183.0 2.5 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 GAP92534.1 - 8e-05 22.6 1.3 0.00016 21.6 0.9 1.6 1 0 0 1 1 1 1 Thioesterase superfamily Tho2 PF11262.3 GAP92535.1 - 1.2e-74 251.1 0.0 1.6e-74 250.6 0.0 1.2 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 GAP92535.1 - 2.8e-27 94.3 0.1 5.6e-27 93.3 0.1 1.5 1 0 0 1 1 1 1 Transcription- and export-related complex subunit DUF432 PF04254.8 GAP92535.1 - 0.0065 16.3 0.0 0.029 14.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF432) Abhydrolase_1 PF00561.15 GAP92536.1 - 2.5e-46 158.1 0.0 6.7e-46 156.6 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAP92536.1 - 3.6e-14 53.1 0.4 2.8e-13 50.2 0.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP92536.1 - 0.0029 17.3 0.1 0.03 14.0 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 GAP92536.1 - 0.016 15.1 0.0 0.043 13.7 0.0 1.7 2 0 0 2 2 2 0 TAP-like protein DUF2424 PF10340.4 GAP92536.1 - 0.19 10.3 0.0 0.3 9.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Sugar_tr PF00083.19 GAP92537.1 - 2.4e-51 174.7 15.1 3.9e-51 174.0 10.5 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP92537.1 - 5.9e-27 94.3 19.9 5.9e-27 94.3 13.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Cyclin_N PF00134.18 GAP92539.1 - 0.0019 17.7 0.0 0.0068 15.9 0.0 1.8 1 1 0 1 1 1 1 Cyclin, N-terminal domain Amidohydro_2 PF04909.9 GAP92540.1 - 6.1e-11 42.3 0.1 2.1e-10 40.6 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 GAP92540.1 - 0.00032 20.8 0.4 0.00054 20.0 0.3 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 GAP92540.1 - 0.0067 16.1 0.0 0.031 13.9 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family CoA_binding_2 PF13380.1 GAP92540.1 - 0.0072 16.4 0.1 0.015 15.4 0.1 1.5 1 0 0 1 1 1 1 CoA binding domain Adenylsucc_synt PF00709.16 GAP92541.1 - 4.1e-147 490.2 0.0 4.7e-147 490.0 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase MBD PF01429.14 GAP92541.1 - 0.015 14.8 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyl-CpG binding domain LcrG PF07216.7 GAP92542.1 - 0.046 13.7 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 LcrG protein Peptidase_M20 PF01546.23 GAP92544.1 - 3.4e-22 78.8 0.0 6.2e-22 78.0 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAP92544.1 - 3.6e-07 29.9 0.0 7.6e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 GAP92544.1 - 0.0011 18.7 0.0 0.0042 16.8 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M28 NR_Repeat PF14046.1 GAP92544.1 - 0.031 13.9 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 Nuclear receptor repeat UTRA PF07702.8 GAP92544.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 UTRA domain Rhomboid PF01694.17 GAP92545.1 - 1e-20 74.2 9.8 1e-20 74.2 6.8 1.7 2 0 0 2 2 2 1 Rhomboid family PhoD PF09423.5 GAP92546.1 - 2e-08 33.2 0.0 1.2e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 PhoD-like phosphatase Aldedh PF00171.17 GAP92547.1 - 4e-107 358.4 0.0 5.1e-107 358.0 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family EHN PF06441.7 GAP92548.1 - 1.4e-35 121.5 0.1 1.3e-34 118.4 0.0 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.15 GAP92548.1 - 2.3e-09 37.1 0.1 6.1e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAP92548.1 - 2.7e-09 37.2 8.2 2.7e-09 37.2 5.7 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Acyl_transf_3 PF01757.17 GAP92549.1 - 8.3e-16 57.7 17.5 8.3e-16 57.7 12.1 2.5 2 1 0 2 2 2 2 Acyltransferase family DUF1962 PF09227.5 GAP92550.1 - 5.8e-36 122.3 21.4 6.9e-36 122.1 14.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1962) DUF3439 PF11921.3 GAP92551.1 - 0.3 10.8 7.0 0.79 9.4 4.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Acyl_transf_3 PF01757.17 GAP92552.1 - 1.8e-32 112.5 34.3 2.5e-32 112.0 23.7 1.2 1 0 0 1 1 1 1 Acyltransferase family DUF1485 PF07364.7 GAP92554.1 - 7.3e-47 159.9 11.7 1.4e-45 155.7 8.1 2.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1485) MlrC_C PF07171.7 GAP92554.1 - 6.7e-26 90.9 7.2 5.2e-13 48.9 0.0 3.7 2 1 1 3 3 3 2 MlrC C-terminus ketoacyl-synt PF00109.21 GAP92555.1 - 8.7e-77 258.0 0.0 2.1e-76 256.7 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.23 GAP92555.1 - 8.2e-75 251.7 0.0 1.3e-74 251.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Acyl_transf_1 PF00698.16 GAP92555.1 - 3.7e-50 171.0 0.0 7.3e-50 170.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Condensation PF00668.15 GAP92555.1 - 5.5e-48 163.3 0.1 1e-47 162.4 0.1 1.4 1 0 0 1 1 1 1 Condensation domain KR PF08659.5 GAP92555.1 - 3.9e-47 160.2 0.0 2.3e-45 154.4 0.0 3.5 4 0 0 4 4 4 1 KR domain adh_short PF00106.20 GAP92555.1 - 3.1e-41 141.0 0.2 2.9e-36 124.9 0.0 4.6 4 0 0 4 4 3 2 short chain dehydrogenase PS-DH PF14765.1 GAP92555.1 - 1.2e-38 133.0 0.0 2.1e-38 132.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase NAD_binding_4 PF07993.7 GAP92555.1 - 1.8e-38 131.8 0.0 3.5e-38 130.9 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 GAP92555.1 - 5.1e-28 97.3 0.0 1.4e-27 95.8 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 GAP92555.1 - 2.9e-17 62.9 0.0 2.5e-16 59.9 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 GAP92555.1 - 6.5e-17 61.5 0.3 8.7e-09 35.5 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.16 GAP92555.1 - 2.7e-15 56.4 0.0 1.5e-13 50.7 0.0 2.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.7 GAP92555.1 - 5.3e-13 49.2 0.0 2.3e-12 47.2 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP92555.1 - 9.2e-13 48.2 0.0 2.6e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP92555.1 - 1.2e-10 41.1 0.0 3.3e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 GAP92555.1 - 1.7e-09 36.8 0.0 3.7e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_18 PF12847.2 GAP92555.1 - 3.1e-08 34.1 0.0 1.3e-07 32.2 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 GAP92555.1 - 3e-07 30.6 0.0 1.3e-06 28.6 0.0 2.1 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_26 PF13659.1 GAP92555.1 - 7.2e-06 26.0 0.0 4e-05 23.6 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP92555.1 - 9.9e-06 25.8 0.0 2.9e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP92555.1 - 8.4e-05 21.7 0.0 0.00017 20.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 GAP92555.1 - 0.00024 20.1 0.0 0.00048 19.1 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 GAP92555.1 - 0.00079 18.9 0.0 0.0019 17.6 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 GAP92555.1 - 0.0027 17.0 0.0 0.0097 15.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase small domain Staphostatin_A PF09022.5 GAP92555.1 - 0.25 11.2 0.0 0.7 9.7 0.0 1.7 1 0 0 1 1 1 0 Staphostatin A AATase PF07247.7 GAP92555.1 - 1.3 7.4 0.0 2.6 6.5 0.0 1.4 1 0 0 1 1 1 0 Alcohol acetyltransferase EthD PF07110.6 GAP92556.1 - 2.3e-11 44.4 0.0 2.9e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 EthD domain MFS_1 PF07690.11 GAP92558.1 - 3.4e-36 124.7 58.4 1.1e-35 122.9 40.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAP92558.1 - 5.6e-14 51.2 17.8 6.9e-14 50.9 12.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_28 PF00295.12 GAP92559.1 - 7e-40 136.9 0.7 7.5e-39 133.5 0.5 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 GAP92559.1 - 0.0021 17.8 0.8 0.0021 17.8 0.6 3.3 2 2 1 3 3 3 2 Right handed beta helix region Bac_rhamnosid PF05592.6 GAP92560.1 - 6.2e-33 113.7 0.1 5.5e-19 67.7 0.3 3.0 3 0 0 3 3 3 3 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 GAP92560.1 - 6.1e-05 21.9 3.7 0.0001 21.1 2.6 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Trehalase PF01204.13 GAP92560.1 - 0.0025 16.5 0.0 0.0039 15.8 0.0 1.2 1 0 0 1 1 1 1 Trehalase Isochorismatase PF00857.15 GAP92561.1 - 2e-19 70.2 0.0 3.9e-19 69.2 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family MMS19_N PF14500.1 GAP92561.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II TrbH PF07283.6 GAP92561.1 - 0.15 11.8 0.0 0.51 10.2 0.0 1.7 2 0 0 2 2 2 0 Conjugal transfer protein TrbH Sugar_tr PF00083.19 GAP92562.1 - 2.1e-122 408.9 25.5 2.4e-122 408.7 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP92562.1 - 1.7e-20 73.0 54.9 1.2e-18 66.9 21.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 GAP92562.1 - 0.038 14.0 0.1 0.038 14.0 0.1 3.5 4 1 1 5 5 5 0 Protein of unknown function (DUF1228) MmgE_PrpD PF03972.9 GAP92563.1 - 6.7e-66 222.2 0.5 8.2e-66 222.0 0.4 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Meth_synt_2 PF01717.13 GAP92564.1 - 7.2e-12 44.9 0.0 1.1e-09 37.7 0.0 2.4 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain TF_Otx PF03529.8 GAP92564.1 - 0.11 12.6 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 Otx1 transcription factor DUF4573 PF15140.1 GAP92565.1 - 6.4e-11 42.1 2.1 3.3e-08 33.3 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4573) Tcp10_C PF07202.8 GAP92565.1 - 0.13 11.7 0.0 0.42 10.1 0.0 1.7 1 1 0 1 1 1 0 T-complex protein 10 C-terminus DNA_methylase PF00145.12 GAP92566.1 - 1.2e-35 123.2 0.0 2.2e-26 92.7 0.0 2.2 1 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase Methyltransf_15 PF09445.5 GAP92566.1 - 0.0042 16.6 0.6 0.0075 15.8 0.1 1.6 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Mannosyl_trans3 PF11051.3 GAP92567.1 - 4.6e-63 213.0 0.0 7e-63 212.5 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative MAP65_ASE1 PF03999.7 GAP92568.1 - 1.8 7.0 4.2 2.1 6.8 2.9 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) F-box-like PF12937.2 GAP92569.1 - 0.031 14.0 3.6 4.1 7.2 0.0 3.0 2 1 0 2 2 2 0 F-box-like DUF500 PF04366.7 GAP92572.1 - 4.3e-44 148.9 0.3 1e-43 147.7 0.1 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF500) SH3_1 PF00018.23 GAP92572.1 - 1.7e-13 49.7 0.3 4.6e-13 48.3 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 GAP92572.1 - 7.4e-13 47.8 0.0 1.6e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAP92572.1 - 8.9e-13 47.5 0.0 1.9e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Synaptobrevin PF00957.16 GAP92573.1 - 0.0023 17.4 0.8 0.01 15.4 0.3 1.9 1 1 1 2 2 2 1 Synaptobrevin DUF4608 PF15381.1 GAP92573.1 - 0.02 15.0 0.2 0.026 14.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4608) DUF4349 PF14257.1 GAP92573.1 - 0.048 12.8 0.1 0.057 12.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) SNARE PF05739.14 GAP92573.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 1 0 1 1 1 0 SNARE domain ArfGap PF01412.13 GAP92575.1 - 1.6e-41 140.7 0.3 2e-41 140.4 0.2 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf NMD3 PF04981.8 GAP92575.1 - 0.14 11.2 0.2 0.19 10.8 0.1 1.1 1 0 0 1 1 1 0 NMD3 family dsrm PF00035.20 GAP92576.1 - 0.0039 17.7 0.0 0.0057 17.2 0.0 1.2 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 GAP92576.1 - 0.014 15.6 0.9 0.13 12.5 0.6 2.1 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Ribosomal_S7 PF00177.16 GAP92577.1 - 3.2e-23 81.9 0.0 5.6e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF3439 PF11921.3 GAP92577.1 - 0.66 9.7 13.1 1.3 8.8 9.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 GAP92577.1 - 6.5 4.6 14.2 8.7 4.1 9.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ran-binding PF05508.6 GAP92578.1 - 6.3e-52 176.3 0.0 7.9e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein GTP_EFTU PF00009.22 GAP92579.1 - 5.6e-42 143.3 0.0 9.8e-42 142.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 GAP92579.1 - 8e-21 74.0 0.1 1.7e-20 72.9 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 GAP92579.1 - 9.1e-07 28.9 1.3 2.8e-06 27.3 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAP92579.1 - 0.00055 19.8 0.0 0.0014 18.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 GAP92579.1 - 0.066 11.8 0.5 0.12 11.0 0.3 1.3 1 0 0 1 1 1 0 G-protein alpha subunit UCH_1 PF13423.1 GAP92580.1 - 6.9e-59 199.6 0.1 9.5e-59 199.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 GAP92580.1 - 2.5e-21 76.6 0.0 4.7e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 GAP92580.1 - 1.4e-10 40.7 0.2 1.4e-09 37.4 0.1 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 GAP92580.1 - 0.055 13.3 0.1 6.3 6.8 0.0 3.8 3 0 0 3 3 3 0 WD domain, G-beta repeat PEPCK_ATP PF01293.15 GAP92581.1 - 1e-215 716.6 0.0 1.2e-215 716.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_29 PF13555.1 GAP92581.1 - 0.092 12.2 0.1 0.26 10.8 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 GAP92581.1 - 0.13 12.1 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain Big_3_2 PF12245.3 GAP92582.1 - 0.005 16.3 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 3) Fungal_trans_2 PF11951.3 GAP92582.1 - 0.033 12.7 0.3 0.047 12.2 0.2 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Ank_2 PF12796.2 GAP92583.1 - 5.8e-15 55.4 0.0 8e-05 22.9 0.0 3.6 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAP92583.1 - 1.1e-09 37.5 0.3 0.07 12.9 0.0 5.7 7 0 0 7 7 7 3 Ankyrin repeat Ank_3 PF13606.1 GAP92583.1 - 2.1e-09 36.7 0.2 1.2 9.5 0.0 5.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 GAP92583.1 - 3.6e-08 33.7 0.1 1.2 9.7 0.0 6.5 5 2 3 8 8 8 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP92583.1 - 2.2e-05 24.5 0.7 0.38 11.0 0.0 4.8 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Fungal_trans PF04082.13 GAP92584.1 - 7.4e-21 74.1 0.2 1.3e-20 73.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cep57_CLD_2 PF14197.1 GAP92584.1 - 0.086 12.8 1.0 0.15 11.9 0.7 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Myosin_tail_1 PF01576.14 GAP92584.1 - 0.19 9.4 0.3 0.25 9.0 0.2 1.0 1 0 0 1 1 1 0 Myosin tail Pox_A_type_inc PF04508.7 GAP92584.1 - 1.1 9.1 12.4 0.026 14.2 4.1 1.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Nol1_Nop2_Fmu PF01189.12 GAP92585.1 - 4.7e-14 52.4 0.1 4.7e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 GAP92585.1 - 0.025 14.5 0.0 0.052 13.5 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase Lipase_GDSL PF00657.17 GAP92585.1 - 0.044 13.6 0.0 0.067 13.0 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase PAT1 PF09770.4 GAP92585.1 - 0.14 10.3 13.2 0.18 10.0 9.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Usp PF00582.21 GAP92588.1 - 6.2e-22 78.2 6.5 8.1e-14 52.0 0.2 2.8 2 1 0 3 3 3 2 Universal stress protein family Peptidase_S8 PF00082.17 GAP92590.1 - 4.9e-16 58.7 0.1 1.3e-15 57.3 0.0 1.7 2 0 0 2 2 2 1 Subtilase family WD40 PF00400.27 GAP92591.1 - 1.6e-67 221.1 17.1 3.1e-11 42.7 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 GAP92591.1 - 0.00026 19.8 0.1 0.32 9.6 0.0 3.4 1 1 1 3 3 3 1 Nup133 N terminal like Nup160 PF11715.3 GAP92591.1 - 0.00038 18.7 1.8 0.03 12.4 0.0 3.3 1 1 2 3 3 3 2 Nucleoporin Nup120/160 AAA PF00004.24 GAP92593.1 - 3.5e-16 59.6 0.0 6.4e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 GAP92593.1 - 5.9e-07 30.3 0.0 0.0027 18.5 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAP92593.1 - 8.6e-05 22.6 0.0 0.0003 20.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAP92593.1 - 0.0012 18.8 0.0 0.0042 17.0 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 GAP92593.1 - 0.0048 16.6 0.0 0.0093 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 GAP92593.1 - 0.048 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 GAP92593.1 - 0.067 13.4 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 GAP92593.1 - 0.099 12.2 0.0 0.35 10.4 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Methyltransf_2 PF00891.13 GAP92595.1 - 1.5e-29 102.9 0.0 1.8e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase DUF3328 PF11807.3 GAP92596.1 - 6.2e-05 22.7 0.9 0.00012 21.7 0.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Methyltransf_2 PF00891.13 GAP92597.1 - 1.1e-37 129.5 0.0 1.6e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 GAP92597.1 - 0.00026 21.5 0.1 0.00078 20.0 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP92597.1 - 0.00045 19.9 0.0 0.00075 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Mucin PF01456.12 GAP92597.1 - 0.0057 16.4 21.0 0.0057 16.4 14.6 2.8 3 0 0 3 3 3 1 Mucin-like glycoprotein SSP160 PF06933.6 GAP92597.1 - 0.06 11.3 18.5 0.099 10.6 12.8 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 AJAP1_PANP_C PF15298.1 GAP92597.1 - 2.6 7.8 15.8 5.7 6.7 11.0 1.5 1 0 0 1 1 1 0 AJAP1/PANP C-terminus DUF3328 PF11807.3 GAP92598.1 - 4.3e-42 144.2 3.1 5.2e-42 143.9 2.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) NAD_binding_8 PF13450.1 GAP92599.1 - 8.3e-06 25.7 0.8 2.1e-05 24.4 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 GAP92599.1 - 7.9e-05 21.8 2.0 0.44 9.5 1.6 2.9 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAP92599.1 - 0.00011 21.3 0.9 0.00021 20.3 0.6 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAP92599.1 - 0.044 14.1 0.1 0.12 12.7 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAP92599.1 - 0.12 12.1 0.1 0.32 10.7 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding JAB PF01398.16 GAP92600.1 - 2.3e-13 49.8 0.0 4.2e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 GAP92600.1 - 9.2e-11 41.7 0.1 1.8e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 GAP92600.1 - 5.1e-06 26.0 0.0 1.1e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Prefoldin_2 PF01920.15 GAP92601.1 - 2.6e-19 68.9 12.5 2.9e-19 68.7 8.6 1.0 1 0 0 1 1 1 1 Prefoldin subunit Spc7 PF08317.6 GAP92601.1 - 0.0032 16.1 6.4 0.0037 15.9 4.5 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein Prefoldin PF02996.12 GAP92601.1 - 0.0035 16.9 6.9 0.021 14.4 0.1 2.2 2 0 0 2 2 2 1 Prefoldin subunit TPR_MLP1_2 PF07926.7 GAP92601.1 - 0.042 13.6 9.0 0.29 10.8 2.0 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Kinesin-relat_1 PF12711.2 GAP92601.1 - 0.058 13.8 4.0 0.12 12.7 0.6 2.1 2 0 0 2 2 2 0 Kinesin motor KH_5 PF13184.1 GAP92601.1 - 0.1 12.3 0.5 0.2 11.4 0.1 1.6 2 0 0 2 2 2 0 NusA-like KH domain WEMBL PF05701.6 GAP92601.1 - 0.11 10.9 10.6 0.23 9.9 6.4 1.8 1 1 1 2 2 2 0 Weak chloroplast movement under blue light DUF4201 PF13870.1 GAP92601.1 - 0.13 11.6 8.1 0.27 10.6 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF4515 PF14988.1 GAP92601.1 - 0.14 11.7 8.6 2.8 7.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) CENP-K PF11802.3 GAP92601.1 - 0.17 11.1 3.0 0.21 10.7 2.1 1.0 1 0 0 1 1 1 0 Centromere-associated protein K DUF677 PF05055.7 GAP92601.1 - 0.17 10.4 2.2 0.25 9.9 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) ACCA PF03255.9 GAP92601.1 - 0.21 11.1 3.7 3.9 7.0 0.1 2.1 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Spc24 PF08286.6 GAP92601.1 - 0.23 11.1 5.7 2.2 7.9 1.2 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Tropomyosin_1 PF12718.2 GAP92601.1 - 0.29 10.9 12.3 3.1 7.6 8.6 1.9 1 1 0 1 1 1 0 Tropomyosin like Rho_Binding PF08912.6 GAP92601.1 - 0.31 11.3 10.0 3.6 7.9 2.4 2.2 2 0 0 2 2 2 0 Rho Binding ADIP PF11559.3 GAP92601.1 - 0.32 10.8 9.3 0.19 11.5 0.3 2.4 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Occludin_ELL PF07303.8 GAP92601.1 - 0.38 11.5 5.3 0.87 10.3 1.0 2.2 2 0 0 2 2 2 0 Occludin homology domain Mnd1 PF03962.10 GAP92601.1 - 0.44 10.1 11.2 2.6 7.6 2.9 2.0 1 1 1 2 2 2 0 Mnd1 family IncA PF04156.9 GAP92601.1 - 0.51 9.8 13.3 2.1 7.8 9.2 1.8 1 1 0 1 1 1 0 IncA protein TMF_TATA_bd PF12325.3 GAP92601.1 - 0.62 9.7 7.7 1.2 8.9 2.2 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Med28 PF11594.3 GAP92601.1 - 0.8 9.9 6.0 2.4 8.4 4.2 1.8 1 1 0 1 1 1 0 Mediator complex subunit 28 PLC-beta_C PF08703.5 GAP92601.1 - 0.84 9.3 11.3 0.29 10.8 0.2 2.5 2 1 1 3 3 3 0 PLC-beta C terminal YgaB PF14182.1 GAP92601.1 - 0.92 9.7 11.1 0.14 12.3 1.3 2.3 1 1 1 2 2 2 0 YgaB-like protein ISG65-75 PF11727.3 GAP92601.1 - 0.97 8.4 3.5 0.44 9.5 0.2 1.8 1 1 1 2 2 2 0 Invariant surface glycoprotein COG2 PF06148.6 GAP92601.1 - 1.1 9.1 7.2 4.3 7.2 1.6 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF848 PF05852.6 GAP92601.1 - 1.1 9.0 5.9 6.4 6.6 1.0 2.1 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) NPV_P10 PF05531.7 GAP92601.1 - 1.5 9.1 6.2 13 6.1 1.5 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein HR1 PF02185.11 GAP92601.1 - 1.6 8.5 8.5 3.3 7.5 0.3 2.6 2 1 0 2 2 2 0 Hr1 repeat Atg14 PF10186.4 GAP92601.1 - 1.8 7.4 11.1 5.6 5.8 7.7 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4140 PF13600.1 GAP92601.1 - 2.1 8.8 8.4 4.8 7.6 2.0 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Cep57_MT_bd PF06657.8 GAP92601.1 - 2.2 8.3 8.4 4 7.4 0.3 2.8 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 TMPIT PF07851.8 GAP92601.1 - 2.5 7.0 5.3 5 6.0 3.7 1.5 1 1 0 1 1 1 0 TMPIT-like protein DivIVA PF05103.8 GAP92601.1 - 3.1 7.8 10.5 11 6.0 0.4 2.6 1 1 1 2 2 2 0 DivIVA protein Mto2_bdg PF12808.2 GAP92601.1 - 3.1 7.9 7.1 8.6 6.5 0.2 3.0 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DivIC PF04977.10 GAP92601.1 - 3.1 7.3 15.7 11 5.5 5.7 3.0 2 1 0 2 2 2 0 Septum formation initiator FKBP_N PF01346.13 GAP92601.1 - 5.1 7.1 8.3 6.7 6.7 2.1 2.1 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Phage_GP20 PF06810.6 GAP92601.1 - 5.3 6.4 13.1 1.3 8.4 1.2 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF1640 PF07798.6 GAP92601.1 - 7.1 6.6 7.3 16 5.4 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) AAA PF00004.24 GAP92602.1 - 2e-42 144.4 0.0 3.5e-42 143.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 GAP92602.1 - 9.2e-27 92.7 0.2 4.3e-26 90.5 0.1 2.3 3 0 0 3 3 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 GAP92602.1 - 1e-21 76.5 1.3 2.8e-21 75.1 0.5 2.0 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 GAP92602.1 - 8.5e-06 26.5 0.1 6.8e-05 23.6 0.0 2.5 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 GAP92602.1 - 1.7e-05 24.5 0.0 0.00016 21.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 GAP92602.1 - 1.9e-05 24.7 0.1 0.0016 18.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 GAP92602.1 - 2.5e-05 23.7 0.0 5.4e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 GAP92602.1 - 2.9e-05 23.2 0.0 6.5e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 GAP92602.1 - 3.1e-05 24.0 0.0 0.0091 16.1 0.0 3.0 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 GAP92602.1 - 4e-05 23.5 0.0 8.4e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 GAP92602.1 - 8.3e-05 22.0 0.4 0.22 10.8 0.1 3.2 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.1 GAP92602.1 - 0.00023 21.2 0.0 0.0041 17.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 GAP92602.1 - 0.00024 19.9 0.0 0.00042 19.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 GAP92602.1 - 0.00034 20.4 0.0 0.00097 19.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 GAP92602.1 - 0.00043 19.2 0.0 0.0009 18.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 GAP92602.1 - 0.0025 17.7 0.0 0.0077 16.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 GAP92602.1 - 0.0048 16.0 0.2 0.19 10.8 0.0 2.5 1 1 1 2 2 2 1 Zeta toxin AAA_24 PF13479.1 GAP92602.1 - 0.0067 16.0 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAP92602.1 - 0.0083 16.4 0.1 0.024 14.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 GAP92602.1 - 0.015 15.0 0.0 0.061 13.0 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 GAP92602.1 - 0.022 14.4 0.6 0.28 10.8 0.0 2.4 2 1 1 3 3 3 0 Archaeal ATPase Mg_chelatase PF01078.16 GAP92602.1 - 0.022 13.9 0.0 0.063 12.4 0.0 1.7 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI ResIII PF04851.10 GAP92602.1 - 0.023 14.5 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.7 GAP92602.1 - 0.036 13.7 0.0 0.25 11.0 0.0 2.1 1 1 0 1 1 1 0 NACHT domain Torsin PF06309.6 GAP92602.1 - 0.038 13.8 0.1 0.1 12.4 0.0 1.7 2 0 0 2 2 1 0 Torsin PhoH PF02562.11 GAP92602.1 - 0.043 13.0 0.0 0.091 11.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 GAP92602.1 - 0.082 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KaiC PF06745.8 GAP92602.1 - 0.096 11.7 0.0 9.2 5.3 0.0 2.2 1 1 1 2 2 2 0 KaiC Sigma54_activat PF00158.21 GAP92602.1 - 0.11 11.9 0.0 0.36 10.2 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_21 PF13304.1 GAP92602.1 - 0.12 12.2 0.2 3.4 7.5 0.0 2.3 1 1 1 2 2 2 0 AAA domain Guanylate_kin PF00625.16 GAP92602.1 - 0.14 11.6 0.0 0.39 10.1 0.0 1.7 1 0 0 1 1 1 0 Guanylate kinase Nop PF01798.13 GAP92603.1 - 3.3e-59 198.4 0.1 1.9e-58 196.0 0.0 2.3 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 GAP92603.1 - 2.1e-18 65.8 0.0 4.4e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 GAP92603.1 - 2.1e-17 63.0 0.0 2.1e-17 63.0 0.0 2.3 2 0 0 2 2 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.6 GAP92603.1 - 0.15 11.7 21.5 0.29 10.7 14.9 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 GAGA_bind PF06217.7 GAP92603.1 - 1.3 8.9 9.7 2 8.2 6.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family AIF_C PF14721.1 GAP92603.1 - 7 6.8 7.4 16 5.7 5.1 1.6 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Glyco_hydro_114 PF03537.8 GAP92604.1 - 1.2e-18 66.6 0.1 3.1e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 DUF1918 PF08940.6 GAP92604.1 - 0.083 12.2 0.1 3.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) Glyco_hydro_18 PF00704.23 GAP92606.1 - 7.8e-93 311.6 0.0 9.2e-93 311.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ubiquitin PF00240.18 GAP92607.1 - 1.5e-34 117.2 0.9 2.7e-34 116.3 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 GAP92607.1 - 1.8e-28 98.0 2.5 3.9e-28 97.0 1.8 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 GAP92607.1 - 1e-19 69.9 0.7 1e-19 69.9 0.5 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 GAP92607.1 - 9.8e-06 25.7 0.8 3.9e-05 23.8 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 GAP92607.1 - 7.1e-05 22.5 0.2 0.00011 21.9 0.2 1.3 1 1 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 GAP92607.1 - 0.00062 19.6 0.8 0.0013 18.5 0.5 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 GAP92607.1 - 0.0038 17.3 0.5 0.0053 16.9 0.4 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 GAP92607.1 - 0.037 14.0 1.1 0.055 13.5 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 GAP92607.1 - 0.1 10.8 2.9 1.9 6.6 0.1 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Ribosomal_S26e PF01283.14 GAP92608.1 - 3e-51 172.4 8.5 3.5e-51 172.2 5.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1918 PF08940.6 GAP92608.1 - 0.02 14.1 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Zn_ribbon_2 PF12674.2 GAP92608.1 - 0.043 14.1 0.3 6.1 7.2 0.0 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain ELYS PF13934.1 GAP92609.1 - 2e-63 214.2 0.2 2.4e-63 213.9 0.2 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly SMC_N PF02463.14 GAP92610.1 - 8.3e-78 260.5 8.5 1.3e-38 132.4 0.5 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 GAP92610.1 - 4.9e-27 94.2 1.2 2e-26 92.3 0.0 2.8 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 GAP92610.1 - 1.8e-12 47.8 5.5 2e-05 24.7 0.0 3.7 5 0 0 5 5 5 2 AAA domain AAA_29 PF13555.1 GAP92610.1 - 0.00031 20.2 0.0 0.00063 19.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 GAP92610.1 - 0.002 17.4 26.4 0.023 13.8 0.5 4.5 3 1 1 4 4 4 3 Reovirus sigma C capsid protein DivIC PF04977.10 GAP92610.1 - 0.0022 17.4 2.6 0.0022 17.4 1.8 11.5 5 4 4 11 11 11 1 Septum formation initiator SbcCD_C PF13558.1 GAP92610.1 - 0.004 17.0 0.7 0.32 10.9 0.0 3.5 3 0 0 3 3 3 1 Putative exonuclease SbcCD, C subunit ERM PF00769.14 GAP92610.1 - 0.0047 16.4 22.4 0.0047 16.4 15.5 6.1 3 2 3 6 6 6 2 Ezrin/radixin/moesin family U79_P34 PF03064.11 GAP92611.1 - 0.056 12.9 0.6 0.062 12.8 0.4 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 FRQ PF09421.5 GAP92611.1 - 2.5 5.7 14.3 3.4 5.3 9.9 1.2 1 1 0 1 1 1 0 Frequency clock protein p450 PF00067.17 GAP92612.1 - 3.9e-41 141.0 0.0 7.7e-25 87.3 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 Glyco_hydro_76 PF03663.9 GAP92613.1 - 2e-58 198.5 2.5 2.5e-58 198.2 1.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 GAP92613.1 - 6.5e-06 25.4 1.2 0.21 10.6 0.3 3.6 2 1 1 4 4 4 3 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 GAP92613.1 - 0.00045 18.6 0.0 0.099 10.8 0.0 2.2 2 0 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) Frag1 PF10277.4 GAP92614.1 - 1.6e-13 50.6 1.4 1.6e-13 50.6 1.0 3.9 3 2 1 4 4 4 2 Frag1/DRAM/Sfk1 family U3_assoc_6 PF08640.6 GAP92615.1 - 2.8e-24 84.6 0.6 7e-23 80.1 0.0 2.8 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.5 GAP92615.1 - 7.5e-05 21.7 1.0 0.00012 21.0 0.1 1.6 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_11 PF13414.1 GAP92615.1 - 0.01 15.4 0.0 0.041 13.5 0.0 2.1 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.1 GAP92615.1 - 0.044 14.4 0.2 51 4.9 0.0 4.1 2 1 2 4 4 4 0 Tetratricopeptide repeat EVE PF01878.13 GAP92616.1 - 3e-48 163.4 0.0 5.1e-48 162.7 0.0 1.3 1 0 0 1 1 1 1 EVE domain ARID PF01388.16 GAP92618.1 - 5.5e-18 64.6 0.0 2.6e-17 62.4 0.0 2.2 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Acetyltransf_1 PF00583.19 GAP92620.1 - 2.5e-15 56.2 0.1 4e-15 55.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAP92620.1 - 2.5e-08 33.9 0.0 3.9e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAP92620.1 - 2e-06 27.9 0.0 2.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAP92620.1 - 0.0013 18.3 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 GAP92620.1 - 0.0024 17.7 0.0 0.01 15.6 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAP92620.1 - 0.0048 16.7 0.0 0.0072 16.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 GAP92620.1 - 0.032 14.1 0.0 0.041 13.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HET PF06985.6 GAP92621.1 - 3.4e-05 24.0 0.0 8.9e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) IncA PF04156.9 GAP92622.1 - 0.0037 16.8 10.9 0.006 16.1 7.6 1.2 1 0 0 1 1 1 1 IncA protein Glyco_hydro_67N PF03648.9 GAP92622.1 - 0.0085 16.1 0.8 0.018 15.0 0.3 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 67 N-terminus AAA_13 PF13166.1 GAP92622.1 - 0.018 13.5 5.7 0.027 12.9 3.9 1.2 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.5 GAP92622.1 - 0.098 12.7 6.3 0.2 11.7 4.2 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Phage_GP20 PF06810.6 GAP92622.1 - 1.2 8.5 8.0 1.7 8.0 1.3 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 GAS PF13851.1 GAP92622.1 - 2.7 7.1 11.7 11 5.1 8.1 1.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 GAP92622.1 - 7.8 6.3 16.3 3 7.6 7.5 2.3 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 p450 PF00067.17 GAP92623.1 - 3.7e-61 207.0 0.0 1.2e-49 169.1 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 HNH_2 PF13391.1 GAP92624.1 - 8.6e-07 28.6 1.1 1.8e-06 27.6 0.8 1.5 1 0 0 1 1 1 1 HNH endonuclease NOA36 PF06524.7 GAP92624.1 - 5.3 6.2 8.3 7.7 5.6 5.7 1.2 1 0 0 1 1 1 0 NOA36 protein CobT PF06213.7 GAP92624.1 - 8.8 5.3 11.5 12 4.8 8.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ank_2 PF12796.2 GAP92625.1 - 4.5e-90 296.1 9.5 9.3e-19 67.5 0.4 10.3 2 2 7 10 10 10 9 Ankyrin repeats (3 copies) Ank PF00023.25 GAP92625.1 - 1.2e-84 274.1 45.3 1.8e-07 30.6 0.3 19.6 20 0 0 20 20 19 17 Ankyrin repeat Ank_4 PF13637.1 GAP92625.1 - 1.1e-78 258.2 24.1 3.7e-11 43.2 0.2 15.1 6 2 9 15 15 15 14 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP92625.1 - 4.9e-59 190.3 33.3 2.8e-05 23.9 0.0 20.4 21 1 0 21 21 20 9 Ankyrin repeat Ank_5 PF13857.1 GAP92625.1 - 3.3e-39 132.0 36.0 6.1e-09 35.8 1.4 13.4 9 4 6 15 15 14 9 Ankyrin repeats (many copies) NACHT PF05729.7 GAP92625.1 - 7.8e-13 48.4 0.0 1.7e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 GAP92625.1 - 0.00031 20.5 0.0 0.00072 19.3 0.0 1.5 2 0 0 2 2 1 1 Archaeal ATPase AAA_16 PF13191.1 GAP92625.1 - 0.00035 20.6 0.0 0.0011 18.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain RVP PF00077.15 GAP92625.1 - 0.00068 19.5 0.2 82 3.2 0.0 7.1 8 1 1 9 9 9 0 Retroviral aspartyl protease RNA_helicase PF00910.17 GAP92625.1 - 0.0017 18.4 0.1 0.0049 17.0 0.0 1.8 2 0 0 2 2 1 1 RNA helicase AAA_22 PF13401.1 GAP92625.1 - 0.0033 17.5 0.0 0.0084 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 GAP92625.1 - 0.008 16.0 0.0 0.076 12.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain DUF3396 PF11876.3 GAP92625.1 - 0.011 14.8 3.3 0.32 10.0 0.0 4.3 4 2 2 6 6 6 0 Protein of unknown function (DUF3396) NB-ARC PF00931.17 GAP92625.1 - 0.017 13.9 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.24 GAP92625.1 - 0.033 14.3 0.1 0.09 12.9 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 GAP92625.1 - 0.12 11.3 0.2 0.77 8.6 0.0 2.0 1 1 1 2 2 2 0 KAP family P-loop domain Glyco_hydro_18 PF00704.23 GAP92627.1 - 1.8e-68 231.5 0.0 2.3e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 GAP92627.1 - 0.0039 17.1 8.1 0.0039 17.1 5.6 4.6 5 0 0 5 5 5 2 Chitin recognition protein Clr5 PF14420.1 GAP92628.1 - 7.1e-21 73.8 0.6 1.6e-20 72.7 0.4 1.7 1 0 0 1 1 1 1 Clr5 domain TPR_7 PF13176.1 GAP92628.1 - 0.18 11.6 0.9 0.7 9.8 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat CLP_protease PF00574.18 GAP92629.1 - 3.9e-72 241.7 0.0 5.2e-72 241.3 0.0 1.1 1 0 0 1 1 1 1 Clp protease SDH_sah PF01972.11 GAP92629.1 - 0.0053 15.5 0.1 0.044 12.5 0.0 1.9 2 0 0 2 2 2 1 Serine dehydrogenase proteinase DUF3491 PF11996.3 GAP92629.1 - 0.056 10.9 0.1 0.07 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3491) Metallophos_2 PF12850.2 GAP92632.1 - 3.6e-07 30.1 0.0 8.4e-07 28.9 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 GAP92632.1 - 4.1e-06 26.3 2.2 4.4e-05 22.9 0.9 2.6 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase DnaJ PF00226.26 GAP92634.1 - 1.9e-20 72.3 1.5 4.4e-20 71.1 1.0 1.7 1 0 0 1 1 1 1 DnaJ domain MBOAT PF03062.14 GAP92635.1 - 6.3e-34 117.5 20.6 6.3e-34 117.5 14.3 2.1 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Flavin_Reduct PF01613.13 GAP92636.1 - 3.5e-20 72.4 0.7 2.3e-19 69.7 0.5 2.1 1 1 0 1 1 1 1 Flavin reductase like domain Utp8 PF10395.4 GAP92636.1 - 0.18 10.0 0.0 0.21 9.8 0.0 1.1 1 0 0 1 1 1 0 Utp8 family Ank_2 PF12796.2 GAP92637.1 - 1.5e-28 98.9 1.3 3.6e-10 40.0 0.1 5.7 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAP92637.1 - 1.8e-20 72.4 5.5 3.9e-10 39.6 0.1 7.7 5 1 3 8 8 8 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAP92637.1 - 7.3e-18 64.5 7.1 2.9e-08 33.9 0.1 7.8 3 2 5 9 9 9 3 Ankyrin repeats (many copies) Ank PF00023.25 GAP92637.1 - 9.5e-16 56.7 13.6 7e-05 22.4 0.0 7.7 8 0 0 8 8 8 3 Ankyrin repeat Ank_3 PF13606.1 GAP92637.1 - 5.1e-12 44.7 5.4 0.0032 17.5 0.0 8.5 9 0 0 9 9 9 2 Ankyrin repeat NACHT PF05729.7 GAP92637.1 - 5e-06 26.2 0.0 1.3e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAP92637.1 - 0.0013 18.9 0.0 0.0056 16.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAP92637.1 - 0.0062 17.3 0.2 0.048 14.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAP92637.1 - 0.078 12.7 0.1 0.52 10.1 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain DUF285 PF03382.9 GAP92637.1 - 0.12 12.0 1.0 0.31 10.5 0.3 2.0 2 0 0 2 2 2 0 Mycoplasma protein of unknown function, DUF285 Dicty_REP PF05086.7 GAP92638.1 - 0.069 10.9 0.8 0.082 10.6 0.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Vps5 PF09325.5 GAP92639.1 - 2.5e-88 295.3 9.6 2.5e-88 295.3 6.6 1.6 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.19 GAP92639.1 - 2.3e-24 85.3 0.1 5.4e-24 84.1 0.0 1.7 1 0 0 1 1 1 1 PX domain BAR PF03114.13 GAP92639.1 - 0.00041 19.9 6.6 0.00074 19.1 4.6 1.4 1 0 0 1 1 1 1 BAR domain BAR_3_WASP_bdg PF10456.4 GAP92639.1 - 0.0022 17.2 1.9 0.032 13.5 1.3 2.2 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein Arfaptin PF06456.8 GAP92639.1 - 0.073 12.4 4.2 0.69 9.2 0.0 2.2 1 1 1 2 2 2 0 Arfaptin-like domain Cortex-I_coil PF09304.5 GAP92639.1 - 3.9 7.5 10.7 4.8 7.2 4.3 2.9 2 1 1 3 3 3 0 Cortexillin I, coiled coil Med11 PF10280.4 GAP92640.1 - 2.1e-26 92.2 0.0 2.6e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein WD40 PF00400.27 GAP92641.1 - 2e-55 182.8 24.5 3.6e-14 52.0 3.3 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 GAP92641.1 - 3.9e-36 124.2 0.0 6e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 GAP92641.1 - 2e-07 30.5 0.0 4.4e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 GAP92641.1 - 1.6e-06 27.9 0.0 0.0027 17.4 0.0 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 GAP92641.1 - 0.093 10.8 2.1 8.3 4.4 0.3 3.2 3 1 0 3 3 3 0 Nucleoporin Nup120/160 AsnC_trans_reg PF01037.16 GAP92641.1 - 0.11 12.1 0.0 0.41 10.3 0.0 1.9 1 0 0 1 1 1 0 AsnC family Pericardin_rpt PF07054.6 GAP92641.1 - 5 7.1 8.6 0.63 9.9 2.8 1.9 2 0 0 2 2 2 0 Pericardin like repeat Glyco_hydro_18 PF00704.23 GAP92642.1 - 3.9e-46 158.0 0.3 5.5e-46 157.5 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_61 PF03443.9 GAP92644.1 - 1.8e-65 220.8 0.0 2e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF1155 PF06633.6 GAP92644.1 - 0.24 10.6 0.1 0.24 10.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1155) AATase PF07247.7 GAP92645.1 - 4.1e-14 51.9 0.0 1e-12 47.3 0.0 2.5 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 GAP92645.1 - 5e-05 22.2 0.0 0.00028 19.8 0.0 2.0 2 0 0 2 2 2 1 Condensation domain WES_acyltransf PF03007.11 GAP92645.1 - 0.0056 16.2 1.3 0.027 14.0 0.2 2.5 2 1 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Aminotran_4 PF01063.14 GAP92646.1 - 7.2e-12 45.2 0.0 2.5e-08 33.6 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class IV DUF3313 PF11769.3 GAP92646.1 - 0.089 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) Thioredoxin PF00085.15 GAP92647.1 - 1.4e-23 82.5 0.0 1.6e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 GAP92647.1 - 2e-08 34.2 0.0 2.5e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 GAP92647.1 - 1.1e-06 28.8 0.2 1.1e-05 25.5 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 GAP92647.1 - 2.6e-05 24.1 0.0 3.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 GAP92647.1 - 0.00011 21.9 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 GAP92647.1 - 0.00031 20.3 0.0 0.00036 20.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 GAP92647.1 - 0.00032 20.2 0.2 0.00074 19.0 0.1 1.5 1 1 1 2 2 2 1 Redoxin DSBA PF01323.15 GAP92647.1 - 0.0046 16.5 1.7 1.6 8.2 0.1 2.2 1 1 1 2 2 2 2 DSBA-like thioredoxin domain TraF PF13728.1 GAP92647.1 - 0.063 12.7 0.0 0.093 12.2 0.0 1.4 1 1 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.1 GAP92647.1 - 0.085 12.8 0.1 8 6.4 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin Fungal_trans PF04082.13 GAP92648.1 - 7.8e-15 54.4 6.4 1.7e-14 53.3 4.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP92648.1 - 1.6e-10 40.6 10.4 3.2e-10 39.7 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cutinase PF01083.17 GAP92649.1 - 1.8e-37 128.8 0.0 2.4e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 GAP92649.1 - 0.00093 18.6 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 GAP92649.1 - 0.0084 15.9 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_5 PF12695.2 GAP92649.1 - 0.03 14.0 0.2 0.04 13.6 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 GAP92649.1 - 0.032 13.6 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 GAP92649.1 - 0.074 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) DUF2855 PF11017.3 GAP92650.1 - 5e-30 104.7 0.0 2.4e-16 59.7 0.3 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF2855) Kinesin PF00225.18 GAP92651.1 - 3.2e-83 279.2 0.1 8.7e-83 277.7 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain CytochromB561_N PF09786.4 GAP92651.1 - 0.24 9.8 10.5 0.47 8.8 7.2 1.4 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF3584 PF12128.3 GAP92651.1 - 0.81 6.9 45.5 0.35 8.1 22.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Flg_hook PF02120.11 GAP92651.1 - 2.7 7.7 12.6 0.071 12.7 1.0 3.0 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK AAA_22 PF13401.1 GAP92651.1 - 5.3 7.1 8.4 0.37 10.9 0.4 3.1 2 2 1 3 3 3 0 AAA domain CobU PF02283.11 GAP92652.1 - 0.62 9.4 3.0 1.2 8.5 2.1 1.4 1 1 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase ABM PF03992.11 GAP92653.1 - 0.0094 15.9 0.1 0.027 14.5 0.1 1.7 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Ank_2 PF12796.2 GAP92653.1 - 0.027 14.8 0.0 0.12 12.7 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) PUF PF00806.14 GAP92654.1 - 2.9e-13 48.4 0.1 0.032 13.7 0.0 6.9 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat Kinesin PF00225.18 GAP92656.1 - 7.5e-82 274.7 0.0 1.1e-81 274.1 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain HHH_3 PF12836.2 GAP92656.1 - 0.00024 20.9 0.0 0.00089 19.1 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.18 GAP92656.1 - 0.00057 19.4 0.0 2 8.2 0.0 2.8 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_5 PF14520.1 GAP92656.1 - 0.044 13.9 0.0 0.18 11.9 0.0 2.1 1 1 0 1 1 1 0 Helix-hairpin-helix domain DUF3701 PF12482.3 GAP92656.1 - 0.081 12.6 0.0 0.31 10.8 0.0 2.0 2 0 0 2 2 2 0 Phage integrase protein ADH_N PF08240.7 GAP92659.1 - 3.5e-28 97.5 1.0 6.8e-28 96.5 0.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAP92659.1 - 8.8e-16 57.6 0.0 1.2e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 GAP92659.1 - 0.0046 17.0 0.0 0.0075 16.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 GAP92659.1 - 0.041 13.8 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Cu-oxidase PF00394.17 GAP92660.1 - 1.1e-35 122.8 0.0 9.6e-33 113.3 0.0 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 GAP92660.1 - 1.4e-30 105.4 0.1 1.4e-30 105.4 0.1 2.6 2 1 1 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 GAP92660.1 - 1.1e-19 70.2 8.4 8.8e-18 64.1 1.2 3.0 2 1 0 2 2 2 2 Multicopper oxidase Abhydrolase_6 PF12697.2 GAP92661.1 - 2.6e-26 92.9 10.0 1.4e-24 87.3 6.9 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP92661.1 - 1.1e-13 51.2 1.1 1.5e-13 50.7 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP92661.1 - 4.3e-10 39.5 0.6 1.1e-08 34.9 0.1 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 GAP92661.1 - 0.0038 17.0 0.0 0.0075 16.0 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 GAP92661.1 - 0.018 14.3 0.1 0.044 13.0 0.1 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family His_Phos_1 PF00300.17 GAP92662.1 - 2.2e-15 57.0 0.0 2.7e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) NACHT PF05729.7 GAP92663.1 - 9.2e-10 38.4 0.0 4.8e-09 36.0 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 GAP92663.1 - 2.4e-05 24.4 0.0 8.5e-05 22.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAP92663.1 - 0.00067 19.6 0.2 0.0036 17.3 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 GAP92663.1 - 0.0025 18.6 0.1 0.014 16.2 0.0 2.4 2 0 0 2 2 1 1 AAA domain AAA_10 PF12846.2 GAP92663.1 - 0.0042 16.5 0.0 0.01 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA-like domain Ank PF00023.25 GAP92663.1 - 0.013 15.3 0.0 2.6 8.0 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat RNA_helicase PF00910.17 GAP92663.1 - 0.013 15.6 0.0 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 GAP92663.1 - 0.013 15.2 0.0 0.042 13.6 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Viral_helicase1 PF01443.13 GAP92663.1 - 0.021 14.3 0.2 0.062 12.8 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 GAP92663.1 - 0.057 12.8 0.1 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 GAP92663.1 - 0.086 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.1 GAP92663.1 - 0.097 12.9 0.0 0.5 10.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 GAP92663.1 - 0.1 12.4 0.9 0.63 9.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 GAP92663.1 - 0.11 11.9 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 GAP92663.1 - 0.11 12.0 0.0 0.36 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain Med9 PF07544.8 GAP92663.1 - 0.18 11.5 1.8 0.56 9.9 1.2 1.9 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 AAA_23 PF13476.1 GAP92663.1 - 0.19 12.0 0.9 2 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 GAP92665.1 - 2.7e-45 153.7 0.4 6.6e-45 152.5 0.0 1.9 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAP92665.1 - 3.5e-09 36.5 0.3 1.2e-08 34.8 0.1 2.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 GAP92665.1 - 4.2e-08 33.2 0.0 9.1e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 GAP92665.1 - 5.1e-07 29.8 0.0 1.7e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAP92665.1 - 7.9e-07 29.2 0.6 0.001 19.1 0.0 2.8 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 GAP92665.1 - 2.8e-06 26.4 0.0 5.4e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 GAP92665.1 - 0.00014 21.7 0.0 0.00059 19.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 GAP92665.1 - 0.00035 19.6 0.0 0.00081 18.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 GAP92665.1 - 0.00042 20.3 0.0 0.00088 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAP92665.1 - 0.00043 21.0 0.0 0.0019 19.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 GAP92665.1 - 0.00068 19.3 0.2 0.056 13.0 0.0 2.9 3 0 0 3 3 3 1 NACHT domain TIP49 PF06068.8 GAP92665.1 - 0.0012 17.7 0.0 0.0021 16.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Zeta_toxin PF06414.7 GAP92665.1 - 0.0013 17.8 0.1 0.0037 16.3 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 GAP92665.1 - 0.0014 18.3 0.2 0.0035 17.0 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 GAP92665.1 - 0.0015 18.7 0.0 0.0033 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.10 GAP92665.1 - 0.0027 17.4 0.0 0.0092 15.6 0.0 1.9 2 0 0 2 2 1 1 NTPase AAA_3 PF07726.6 GAP92665.1 - 0.0037 16.8 0.0 0.011 15.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 GAP92665.1 - 0.0039 16.7 0.0 0.015 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 GAP92665.1 - 0.0046 16.5 0.0 0.039 13.5 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 GAP92665.1 - 0.0054 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 GAP92665.1 - 0.0056 16.4 0.5 0.06 13.0 0.0 2.6 2 1 1 3 3 3 1 Archaeal ATPase Mg_chelatase PF01078.16 GAP92665.1 - 0.0067 15.6 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 GAP92665.1 - 0.0068 15.8 0.8 0.078 12.3 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_23 PF13476.1 GAP92665.1 - 0.0085 16.4 0.5 0.79 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 GAP92665.1 - 0.0096 15.5 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 GAP92665.1 - 0.011 15.1 0.4 0.024 14.0 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 GAP92665.1 - 0.012 15.2 0.1 0.03 13.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 GAP92665.1 - 0.018 14.6 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein KaiC PF06745.8 GAP92665.1 - 0.026 13.6 0.9 0.45 9.5 0.0 2.6 3 0 0 3 3 3 0 KaiC AAA_18 PF13238.1 GAP92665.1 - 0.029 14.6 0.0 0.099 12.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 GAP92665.1 - 0.046 13.1 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 GAP92665.1 - 0.063 13.3 0.1 0.31 11.0 0.0 2.2 2 1 0 2 2 1 0 Sigma-54 interaction domain AFG1_ATPase PF03969.11 GAP92665.1 - 0.075 11.8 0.0 0.13 10.9 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase NB-ARC PF00931.17 GAP92665.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 GAP92665.1 - 0.17 10.7 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Methyltransf_16 PF10294.4 GAP92667.1 - 1.1e-30 106.3 0.0 3.6e-30 104.6 0.0 1.8 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 GAP92667.1 - 0.00049 19.8 0.0 0.00081 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAP92667.1 - 0.048 13.0 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Mis14 PF08641.7 GAP92668.1 - 0.00018 21.5 1.5 0.00062 19.8 0.0 2.3 2 1 1 3 3 3 1 Kinetochore protein Mis14 like IGF2_C PF08365.6 GAP92668.1 - 6.5 6.5 8.5 11 5.8 0.3 3.1 2 1 1 3 3 3 0 Insulin-like growth factor II E-peptide CRAL_TRIO PF00650.15 GAP92669.1 - 8.8e-32 109.7 0.0 1.4e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAP92669.1 - 4.5e-10 39.5 1.1 1e-09 38.3 0.2 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 GAP92669.1 - 0.0042 16.9 0.0 0.0093 15.8 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Prefoldin PF02996.12 GAP92670.1 - 3.7e-33 113.7 0.0 5.3e-33 113.2 0.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 GAP92670.1 - 0.00094 18.9 0.6 0.012 15.3 0.0 2.4 3 0 0 3 3 3 1 Prefoldin subunit HR1 PF02185.11 GAP92670.1 - 0.021 14.5 0.1 0.22 11.2 0.0 2.1 2 0 0 2 2 2 0 Hr1 repeat HET PF06985.6 GAP92671.1 - 2.3e-14 53.7 2.8 6.1e-11 42.6 0.1 2.1 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Pkinase_Tyr PF07714.12 GAP92672.1 - 7.2e-18 64.5 0.0 2.6e-17 62.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAP92672.1 - 1.3e-15 57.3 0.0 1.6e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 GAP92672.1 - 0.026 13.5 0.0 0.032 13.2 0.0 1.1 1 0 0 1 1 1 0 Kinase-like FRQ PF09421.5 GAP92673.1 - 5.4e-248 825.5 68.1 3.5e-247 822.9 47.2 1.9 1 1 0 1 1 1 1 Frequency clock protein Glypican PF01153.14 GAP92673.1 - 0.91 8.0 6.6 0.1 11.1 0.8 2.0 2 0 0 2 2 2 0 Glypican DUF1237 PF06824.6 GAP92674.1 - 1.6e-141 471.7 0.0 2.9e-111 372.0 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1237) DUF2434 PF10361.4 GAP92675.1 - 2.3e-110 368.3 7.6 3.1e-110 367.9 5.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) Polysacc_deac_1 PF01522.16 GAP92676.1 - 5.1e-27 93.9 0.0 7.1e-27 93.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 GAP92676.1 - 0.0095 14.8 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Amidoligase_2 PF12224.3 GAP92677.1 - 5e-22 78.7 0.0 1.4e-16 60.9 0.0 2.4 2 0 0 2 2 2 2 Putative amidoligase enzyme DEAD PF00270.24 GAP92678.1 - 1.2e-42 145.3 0.1 4.7e-41 140.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP92678.1 - 2.2e-20 72.2 0.1 6.9e-20 70.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAP92678.1 - 3.8e-05 23.5 0.0 7.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 GAP92678.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain Tannase PF07519.6 GAP92679.1 - 1.7e-94 317.2 0.0 1.9e-94 317.0 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 GAP92679.1 - 0.0012 18.7 0.0 0.0041 17.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP92679.1 - 0.003 17.3 0.1 0.53 10.0 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAP92679.1 - 0.0063 15.7 0.2 3 6.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Lycopene_cycl PF05834.7 GAP92680.1 - 0.042 12.7 0.3 0.055 12.3 0.2 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein APOBEC_C PF05240.9 GAP92680.1 - 0.15 11.4 0.5 3.3 7.1 0.1 2.4 2 0 0 2 2 2 0 APOBEC-like C-terminal domain Phycobilisome PF00502.14 GAP92683.1 - 0.088 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Phycobilisome protein zf-MYND PF01753.13 GAP92684.1 - 5.4e-08 32.5 11.3 2.2e-07 30.6 7.8 2.1 1 0 0 1 1 1 1 MYND finger Glyco_transf_90 PF05686.7 GAP92686.1 - 1.1e-17 63.8 0.0 8.9e-14 50.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 90 DUF2763 PF10961.3 GAP92686.1 - 2.7 8.4 10.8 8.6 6.8 7.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) G-patch_2 PF12656.2 GAP92687.1 - 0.069 13.0 0.5 0.1 12.4 0.3 1.3 1 0 0 1 1 1 0 DExH-box splicing factor binding site Clr5 PF14420.1 GAP92688.1 - 4e-14 52.2 0.0 1.1e-13 50.8 0.0 1.8 1 0 0 1 1 1 1 Clr5 domain Ank_3 PF13606.1 GAP92688.1 - 0.089 13.0 0.1 13 6.3 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeat Amidohydro_1 PF01979.15 GAP92689.1 - 1.6e-15 57.6 0.0 3.6e-15 56.4 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 GAP92689.1 - 2.2e-14 52.9 0.2 1.7e-13 50.1 0.0 2.6 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 GAP92689.1 - 2.9e-08 34.0 0.0 3.8e-06 27.1 0.0 2.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 GAP92689.1 - 2.4e-06 27.0 0.3 0.00099 18.4 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Serglycin PF04360.7 GAP92689.1 - 0.012 15.3 5.9 0.027 14.2 4.1 1.5 1 0 0 1 1 1 0 Serglycin Cyto_heme_lyase PF01265.12 GAP92690.1 - 3.3e-76 256.2 0.0 4e-76 256.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase FA_desaturase PF00487.19 GAP92691.1 - 2.7e-39 135.1 23.9 3.6e-39 134.7 16.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 GAP92691.1 - 8e-09 35.1 0.0 1.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ABC1 PF03109.11 GAP92692.1 - 4.9e-24 84.5 0.0 5e-15 55.5 0.0 2.5 1 1 1 2 2 2 2 ABC1 family APH PF01636.18 GAP92692.1 - 0.00015 21.6 0.1 0.0004 20.1 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Cellulase PF00150.13 GAP92695.1 - 7.7e-20 71.2 6.1 1e-19 70.8 4.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Apis_Csd PF11671.3 GAP92695.1 - 0.18 11.5 3.8 0.053 13.3 0.6 1.6 2 0 0 2 2 2 0 Complementary sex determiner protein GST_N_3 PF13417.1 GAP92697.1 - 2.3e-06 27.7 0.0 4.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAP92697.1 - 7.8e-06 25.7 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAP92697.1 - 2.6e-05 24.1 0.0 5.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAP92697.1 - 3e-05 24.0 0.0 5.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAP92697.1 - 0.00015 22.1 0.0 0.00026 21.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAP92697.1 - 0.003 17.4 0.1 0.0053 16.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain p450 PF00067.17 GAP92700.1 - 9.9e-24 83.6 0.0 1.9e-23 82.7 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 NACHT PF05729.7 GAP92702.1 - 3.1e-07 30.1 0.0 7.4e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 GAP92702.1 - 3.5e-05 23.8 0.0 0.00017 21.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 GAP92702.1 - 5.2e-05 22.2 0.0 0.00023 20.1 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain AAA_18 PF13238.1 GAP92702.1 - 0.00027 21.2 0.0 0.75 10.1 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAP92702.1 - 0.00043 20.4 0.0 0.0017 18.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 GAP92702.1 - 0.0055 16.4 0.0 0.042 13.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Tnp_DNA_bind PF14706.1 GAP92702.1 - 0.023 14.3 0.0 0.068 12.8 0.0 1.8 1 0 0 1 1 1 0 Transposase DNA-binding 7TM_GPCR_Srj PF10319.4 GAP92702.1 - 0.054 12.5 0.3 0.096 11.7 0.2 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srj RNA_helicase PF00910.17 GAP92702.1 - 0.08 13.1 0.0 0.25 11.5 0.0 1.9 1 0 0 1 1 1 0 RNA helicase SNF2_N PF00176.18 GAP92703.1 - 9.6e-59 198.6 0.0 1.4e-58 198.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAP92703.1 - 3.8e-11 42.6 0.0 7.8e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAP92703.1 - 0.00027 20.8 0.0 0.0016 18.2 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2420 PF10336.4 GAP92703.1 - 0.0045 16.5 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) zf-RING_5 PF14634.1 GAP92703.1 - 0.23 11.2 4.4 0.53 10.0 3.1 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Pkinase PF00069.20 GAP92704.1 - 3.7e-47 160.6 0.0 4.9e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP92704.1 - 5.3e-29 101.0 0.0 1e-28 100.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RicinB_lectin_2 PF14200.1 GAP92704.1 - 1.1e-08 35.3 0.5 2.9e-05 24.3 0.1 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Kinase-like PF14531.1 GAP92704.1 - 0.00054 18.9 0.0 0.00093 18.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAP92704.1 - 0.0022 17.0 0.0 0.0044 16.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Protamine_P2 PF00841.14 GAP92704.1 - 0.11 13.0 0.5 0.77 10.3 0.1 2.3 2 0 0 2 2 2 0 Sperm histone P2 LIM_bind PF01803.11 GAP92706.1 - 0.014 14.5 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 LIM-domain binding protein DUF3112 PF11309.3 GAP92708.1 - 0.27 10.9 4.5 4.1 7.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3112) MFS_1 PF07690.11 GAP92710.1 - 4.6e-30 104.5 20.4 4.6e-30 104.5 14.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TauD PF02668.11 GAP92711.1 - 4.9e-11 42.7 0.0 5.7e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_hydro_31 PF01055.21 GAP92712.1 - 9.2e-156 519.0 4.8 1.2e-155 518.6 3.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 GAP92712.1 - 1.5e-22 79.2 0.1 4.2e-22 77.7 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like NDK PF00334.14 GAP92713.1 - 4.3e-54 181.9 0.0 5.4e-54 181.6 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase FLILHELTA PF10306.4 GAP92714.1 - 7.3e-19 67.5 0.0 1.5e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 GAP92714.1 - 0.08 13.2 0.1 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) Melibiase PF02065.13 GAP92717.1 - 4.8e-23 81.4 4.0 7.9e-21 74.1 2.8 3.1 1 1 0 1 1 1 1 Melibiase Sensor PF13796.1 GAP92718.1 - 0.16 11.5 4.2 0.12 11.9 0.3 2.1 1 1 1 2 2 2 0 Putative sensor N2227 PF07942.7 GAP92720.1 - 1.5e-92 309.4 0.0 2.1e-92 308.9 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 GAP92720.1 - 3.9e-07 29.9 0.0 6.4e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP92720.1 - 0.00028 21.3 0.0 0.00076 19.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP92720.1 - 0.00039 20.8 0.0 0.0024 18.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP92720.1 - 0.098 13.2 0.0 0.49 10.9 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 GAP92720.1 - 0.17 11.4 0.0 0.45 10.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain adh_short PF00106.20 GAP92721.1 - 2.1e-23 83.0 6.4 3.4e-23 82.4 4.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP92721.1 - 2.4e-19 70.0 0.0 3.5e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP92721.1 - 3.6e-10 39.8 2.0 6e-10 39.0 1.4 1.3 1 0 0 1 1 1 1 KR domain malic PF00390.14 GAP92721.1 - 0.16 11.5 0.0 2.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Malic enzyme, N-terminal domain Tau95 PF09734.4 GAP92722.1 - 2.6e-60 204.3 0.0 3.2e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit B56 PF01603.15 GAP92723.1 - 8e-172 571.4 5.9 9.6e-172 571.1 4.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) PS_Dcarbxylase PF02666.10 GAP92724.1 - 8.1e-81 270.1 0.0 3e-80 268.2 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase DUF2407 PF10302.4 GAP92725.1 - 1.4e-06 28.4 0.1 3.7e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 GAP92725.1 - 1.9e-06 27.1 0.0 6.4e-06 25.4 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin family Zip PF02535.17 GAP92725.1 - 0.26 10.2 7.4 0.61 9.0 5.1 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 GAP92725.1 - 0.32 10.3 16.1 0.18 11.1 6.6 2.4 2 0 0 2 2 2 0 Selenoprotein P, N terminal region NicO PF03824.11 GAP92725.1 - 1.4 8.1 4.1 32 3.6 0.0 2.3 2 0 0 2 2 2 0 High-affinity nickel-transport protein UvdE PF03851.9 GAP92726.1 - 0.04 12.9 0.1 0.079 11.9 0.1 1.4 1 0 0 1 1 1 0 UV-endonuclease UvdE Zip PF02535.17 GAP92726.1 - 0.51 9.2 2.0 0.72 8.7 1.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Longin PF13774.1 GAP92727.1 - 2.3e-27 94.3 0.3 3.7e-27 93.7 0.2 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 GAP92727.1 - 1.7e-17 62.7 0.5 2.6e-17 62.1 0.1 1.6 2 0 0 2 2 2 1 Synaptobrevin DUF1664 PF07889.7 GAP92727.1 - 0.035 13.9 0.2 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4404 PF14357.1 GAP92727.1 - 0.21 12.0 1.9 7.4 7.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) ASXH PF13919.1 GAP92728.1 - 9.1e-19 67.6 0.0 1.6e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Asx homology domain TRAPPC9-Trs120 PF08626.6 GAP92729.1 - 2.4e-154 515.4 0.0 2.1e-153 512.2 0.0 2.0 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit adh_short PF00106.20 GAP92730.1 - 1.9e-08 34.3 0.0 3.8e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP92730.1 - 4.1e-08 33.2 0.0 6.5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 GAP92730.1 - 0.042 12.9 0.0 0.065 12.3 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) KR PF08659.5 GAP92730.1 - 0.045 13.4 0.0 0.094 12.3 0.0 1.7 1 1 0 1 1 1 0 KR domain DUF904 PF06005.7 GAP92730.1 - 0.11 12.8 0.3 0.35 11.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF2264 PF10022.4 GAP92731.1 - 2.8e-127 424.3 0.1 3.7e-127 423.9 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Surf_Ag_VNR PF07244.10 GAP92731.1 - 0.23 11.8 0.0 0.49 10.8 0.0 1.5 1 0 0 1 1 1 0 Surface antigen variable number repeat AMP-binding PF00501.23 GAP92732.1 - 2.1e-46 158.1 0.0 3e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF1757 PF08560.5 GAP92733.1 - 0.18 11.4 3.3 0.83 9.3 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1757) WD40 PF00400.27 GAP92734.1 - 4.1e-35 118.4 14.1 6.1e-09 35.4 0.1 7.6 8 0 0 8 8 8 5 WD domain, G-beta repeat Dynamin_M PF01031.15 GAP92735.1 - 1e-101 339.6 0.0 1.8e-101 338.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 GAP92735.1 - 3e-55 186.6 0.0 5.2e-55 185.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 GAP92735.1 - 2.3e-29 101.1 2.9 4.7e-29 100.1 0.8 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 GAP92735.1 - 8.6e-05 22.4 0.3 0.0016 18.3 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAP92735.1 - 0.018 15.5 0.0 0.042 14.3 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein CoA_transf_3 PF02515.12 GAP92736.1 - 2.8e-53 180.0 0.6 4.2e-53 179.4 0.4 1.3 1 0 0 1 1 1 1 CoA-transferase family III UPF0029 PF01205.14 GAP92736.1 - 2.4e-30 104.4 0.0 3.8e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Metallophos PF00149.23 GAP92737.1 - 1.1e-38 132.6 0.1 1.7e-38 132.0 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 GAP92737.1 - 2.9e-30 104.1 1.6 5.2e-30 103.3 0.5 1.9 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_11 PF13414.1 GAP92737.1 - 2e-28 97.7 5.8 1.3e-16 60.0 0.5 2.5 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 GAP92737.1 - 1.2e-20 72.2 0.8 6.2e-07 28.7 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAP92737.1 - 4.5e-15 54.2 0.4 3.6e-05 23.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 GAP92737.1 - 4.9e-10 38.8 0.9 0.0078 16.3 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 GAP92737.1 - 2.7e-06 27.5 0.1 0.079 13.6 0.0 3.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAP92737.1 - 1.5e-05 25.1 0.1 0.025 14.8 0.0 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAP92737.1 - 3e-05 24.5 0.6 0.5 11.1 0.0 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAP92737.1 - 0.0022 17.8 0.0 0.12 12.2 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 GAP92737.1 - 0.0044 17.3 0.3 0.27 11.7 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAP92737.1 - 0.013 15.2 0.4 0.35 10.7 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 GAP92737.1 - 0.017 14.3 0.0 1.1 8.6 0.0 2.8 3 0 0 3 3 3 0 SHNi-TPR TPR_12 PF13424.1 GAP92737.1 - 0.028 14.3 0.0 2 8.3 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.1 GAP92737.1 - 0.071 12.1 0.1 5.3 6.0 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 GAP92737.1 - 0.097 12.8 1.1 1.9 8.6 0.9 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Spt4 PF06093.8 GAP92738.1 - 5.5e-32 109.4 0.2 6.6e-32 109.2 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger BAF1_ABF1 PF04684.8 GAP92739.1 - 0.49 9.1 24.6 0.012 14.4 5.9 2.7 3 0 0 3 3 3 0 BAF1 / ABF1 chromatin reorganising factor MACPF PF01823.14 GAP92739.1 - 1.1 8.9 12.1 4.1 7.0 2.8 2.5 2 0 0 2 2 2 0 MAC/Perforin domain WD40 PF00400.27 GAP92740.1 - 7.3e-37 123.9 9.2 1.6e-08 34.1 0.0 6.9 6 1 1 7 7 7 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 GAP92740.1 - 1.2e-28 98.8 0.2 3.5e-28 97.3 0.1 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Apc4_WD40 PF12894.2 GAP92740.1 - 0.0011 18.3 0.0 0.036 13.5 0.0 2.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4059 PF13268.1 GAP92740.1 - 0.21 11.8 0.0 0.44 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4059) E1-E2_ATPase PF00122.15 GAP92741.1 - 9e-17 60.8 0.0 2.2e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 GAP92741.1 - 1.2e-16 61.8 0.0 5.1e-16 59.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAP92741.1 - 2.4e-09 37.6 0.0 7.5e-09 36.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAP92741.1 - 4.2e-05 23.4 0.0 0.00015 21.6 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAP92741.1 - 0.0016 18.0 0.0 0.004 16.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribonuc_L-PSP PF01042.16 GAP92742.1 - 1.4e-38 131.3 0.0 1.6e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF605 PF04652.11 GAP92743.1 - 0.3 10.4 7.4 0.31 10.4 5.2 1.1 1 0 0 1 1 1 0 Vta1 like Totivirus_coat PF05518.6 GAP92743.1 - 5.5 4.6 7.2 6.4 4.4 5.0 1.1 1 0 0 1 1 1 0 Totivirus coat protein DUF2360 PF10152.4 GAP92743.1 - 8 6.7 7.6 0.6 10.3 2.2 1.6 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) LETM1 PF07766.8 GAP92744.1 - 0.0013 17.8 0.0 0.0018 17.3 0.0 1.1 1 0 0 1 1 1 1 LETM1-like protein RRM_1 PF00076.17 GAP92745.1 - 1.6e-09 37.2 0.2 1.2e-08 34.4 0.1 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP92745.1 - 8.5e-08 32.0 0.0 1.6e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP92745.1 - 2.1e-07 30.6 0.3 6.8e-07 29.0 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RF-1 PF00472.15 GAP92746.1 - 4.2e-13 49.0 3.6 7.3e-13 48.3 2.4 1.5 1 1 0 1 1 1 1 RF-1 domain Pkinase PF00069.20 GAP92747.1 - 3.1e-68 229.7 0.0 3.8e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP92747.1 - 1.6e-29 102.7 0.0 2.2e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP92747.1 - 2.6e-06 26.5 0.0 6.4e-06 25.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 GAP92747.1 - 0.0002 21.1 0.0 0.00029 20.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 GAP92747.1 - 0.00045 19.3 0.0 0.00095 18.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 GAP92747.1 - 0.036 13.4 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL SnoaL_2 PF12680.2 GAP92748.1 - 9.3e-05 22.7 0.9 0.00037 20.8 0.6 2.0 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 GAP92748.1 - 0.00051 19.6 0.1 0.0009 18.8 0.1 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase 2-Hacid_dh_C PF02826.14 GAP92750.1 - 1.4e-49 167.7 0.0 1.8e-49 167.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAP92750.1 - 1.9e-16 59.7 0.0 2.7e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 GAP92750.1 - 0.0015 18.3 0.2 0.0027 17.5 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.1 GAP92750.1 - 0.016 15.5 0.1 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain F420_oxidored PF03807.12 GAP92750.1 - 0.098 13.1 1.1 0.21 12.0 0.8 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 GAP92750.1 - 0.14 12.1 2.6 0.37 10.7 1.8 1.9 1 1 0 1 1 1 0 NADH(P)-binding Pyr_redox PF00070.22 GAP92750.1 - 0.16 12.3 0.5 19 5.7 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RNA_polI_A34 PF08208.6 GAP92751.1 - 3.8e-23 82.2 16.2 3.8e-23 82.2 11.2 4.4 2 2 0 3 3 3 1 DNA-directed RNA polymerase I subunit RPA34.5 FAD_binding_3 PF01494.14 GAP92752.1 - 3.4e-87 292.8 0.0 5.2e-87 292.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 GAP92752.1 - 3.8e-48 163.2 0.0 7e-48 162.4 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Clp1 PF06807.9 GAP92752.1 - 3.3e-05 23.7 0.0 0.032 13.9 0.0 2.5 2 0 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 Thi4 PF01946.12 GAP92752.1 - 0.00034 19.7 0.1 0.018 14.1 0.0 2.3 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 GAP92752.1 - 0.0017 16.9 0.1 0.0025 16.3 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 GAP92752.1 - 0.0019 17.1 0.0 0.005 15.7 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAP92752.1 - 0.003 16.5 0.1 0.0049 15.8 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 GAP92752.1 - 0.0055 16.7 0.1 0.015 15.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAP92752.1 - 0.011 15.6 0.1 0.068 13.0 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAP92752.1 - 0.031 13.1 0.2 0.05 12.4 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 GAP92752.1 - 0.043 13.8 0.2 0.16 12.0 0.1 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MobB PF03205.9 GAP92752.1 - 0.052 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Pyr_redox PF00070.22 GAP92752.1 - 0.052 13.9 0.1 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAP92752.1 - 0.089 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF4217 PF13959.1 GAP92753.1 - 0.036 13.6 0.0 0.069 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) Glyco_hydro_2_C PF02836.12 GAP92753.1 - 0.04 12.8 0.0 0.065 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain DUF4185 PF13810.1 GAP92754.1 - 3.1e-09 36.1 5.1 3.1e-09 36.1 3.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4185) Peptidase_C12 PF01088.16 GAP92755.1 - 7.1e-46 156.0 0.0 9e-46 155.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Annexin PF00191.15 GAP92756.1 - 4.6e-20 71.2 2.1 8.1e-05 22.4 0.0 4.4 4 0 0 4 4 4 4 Annexin GPI2 PF06432.6 GAP92758.1 - 6.5e-119 396.4 0.1 7.8e-119 396.1 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase zf-C2H2 PF00096.21 GAP92759.1 - 3.6e-11 42.7 11.4 2.5e-05 24.3 0.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAP92759.1 - 2.4e-10 40.1 4.4 3.5e-07 30.1 0.6 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAP92759.1 - 1.2e-07 31.5 7.6 0.00036 20.6 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAP92759.1 - 0.00017 21.6 1.9 0.025 14.6 0.0 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 GAP92759.1 - 0.0086 16.2 1.9 0.0086 16.2 1.3 3.0 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-met PF12874.2 GAP92759.1 - 0.055 13.7 2.3 9 6.6 0.4 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF1635 PF07795.6 GAP92759.1 - 0.16 11.3 0.8 0.3 10.4 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) zf-BED PF02892.10 GAP92759.1 - 0.23 11.2 2.8 1.6 8.5 0.1 2.5 2 0 0 2 2 2 0 BED zinc finger BolA PF01722.13 GAP92759.1 - 0.66 9.9 4.0 2.8 7.9 0.0 2.6 2 1 1 3 3 3 0 BolA-like protein zf-C2H2_6 PF13912.1 GAP92759.1 - 0.93 9.4 4.0 21 5.1 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger DUF464 PF04327.7 GAP92761.1 - 0.013 15.7 0.0 0.023 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF464) Peptidase_M35 PF02102.10 GAP92761.1 - 0.23 10.1 0.0 0.33 9.5 0.0 1.1 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family Ctr PF04145.10 GAP92762.1 - 2.5e-27 95.7 0.5 2.9e-27 95.4 0.3 1.0 1 0 0 1 1 1 1 Ctr copper transporter family PAP2 PF01569.16 GAP92762.1 - 0.088 12.4 4.6 0.37 10.4 0.1 2.1 2 0 0 2 2 2 0 PAP2 superfamily SRF-TF PF00319.13 GAP92763.1 - 8.7e-24 82.5 0.4 1.2e-23 82.0 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.9 GAP92763.1 - 0.075 11.0 0.2 0.098 10.6 0.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Tetraspannin PF00335.15 GAP92765.1 - 1.4e-07 30.9 5.5 2.6e-07 30.1 3.8 1.4 1 1 0 1 1 1 1 Tetraspanin family VanZ PF04892.7 GAP92765.1 - 0.097 12.6 2.5 0.11 12.4 1.0 1.8 2 0 0 2 2 2 0 VanZ like family YfzA PF14118.1 GAP92765.1 - 0.5 10.5 3.9 1.4 9.0 0.2 2.5 3 0 0 3 3 3 0 YfzA-like protein F-box-like PF12937.2 GAP92767.1 - 5.7e-14 51.5 1.4 5.7e-14 51.5 1.0 2.3 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 GAP92767.1 - 7.9e-12 44.5 12.7 0.013 15.1 0.0 7.2 7 1 1 8 8 8 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 GAP92767.1 - 4.1e-11 41.7 17.2 26 5.2 0.1 12.0 12 0 0 12 12 12 0 Leucine Rich repeat LRR_8 PF13855.1 GAP92767.1 - 6.7e-11 41.7 19.7 1.1e-05 25.0 0.7 6.1 3 1 4 7 7 7 6 Leucine rich repeat LRR_1 PF00560.28 GAP92767.1 - 2e-05 23.9 28.3 4.9 7.5 0.0 10.8 11 2 0 11 11 11 2 Leucine Rich Repeat F-box PF00646.28 GAP92767.1 - 0.00023 20.7 0.7 0.001 18.6 0.6 2.2 2 0 0 2 2 2 1 F-box domain DUF1699 PF08004.6 GAP92767.1 - 0.47 9.9 1.4 3 7.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1699) PSDC PF12588.3 GAP92768.1 - 4.4e-34 117.1 0.0 2.8e-29 101.5 0.0 2.2 1 1 1 2 2 2 2 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 GAP92768.1 - 5.5e-32 110.7 0.0 7.8e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.1 GAP92768.1 - 0.06 13.0 1.1 1.4 8.6 0.2 2.4 2 0 0 2 2 2 0 Biotin-lipoyl like Fungal_trans PF04082.13 GAP92769.1 - 6.2e-06 25.2 0.0 1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP92769.1 - 2.2e-05 24.2 13.4 4.5e-05 23.2 9.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 GAP92770.1 - 5.3e-89 298.8 25.8 6.2e-89 298.6 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP92770.1 - 6.7e-13 48.0 42.7 4.7e-07 28.8 12.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 GAP92772.1 - 1.9e-31 109.0 1.1 4.2e-17 61.8 0.0 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain DUF1110 PF06533.7 GAP92772.1 - 0.016 15.0 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1110) DIOX_N PF14226.1 GAP92773.1 - 0.00067 20.1 0.0 0.00095 19.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal BAR PF03114.13 GAP92774.1 - 4.9e-47 160.3 6.8 6e-47 160.0 4.7 1.1 1 0 0 1 1 1 1 BAR domain Apo-CIII PF05778.7 GAP92774.1 - 0.097 12.0 0.2 0.34 10.3 0.0 1.9 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) 5_nucleotid_C PF02872.13 GAP92775.1 - 8.8e-35 119.9 0.1 2.1e-34 118.7 0.0 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 GAP92775.1 - 6.9e-14 51.7 0.1 9.5e-13 47.9 0.1 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase PGA_cap PF09587.5 GAP92775.1 - 0.0006 19.2 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap YmdB PF13277.1 GAP92775.1 - 0.0024 16.9 0.0 0.0039 16.2 0.0 1.4 1 0 0 1 1 1 1 YmdB-like protein Acyltransferase PF01553.16 GAP92776.1 - 3.6e-25 87.9 0.0 5.4e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF2305 PF10230.4 GAP92777.1 - 9.5e-52 176.0 0.0 5.2e-51 173.6 0.0 1.8 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 GAP92777.1 - 7.2e-10 39.1 7.2 9e-10 38.8 5.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP92777.1 - 3.9e-07 29.9 0.1 5.7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 GAP92777.1 - 0.00014 21.5 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 GAP92777.1 - 0.059 13.5 0.3 0.13 12.4 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_2 PF02230.11 GAP92777.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Glyco_hydro_72 PF03198.9 GAP92778.1 - 4.9e-121 403.5 0.4 6.4e-121 403.1 0.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 GAP92778.1 - 2.3e-23 82.4 3.5 7.1e-23 80.8 2.4 1.9 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 GAP92778.1 - 0.00069 18.6 0.0 0.0015 17.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain TauD PF02668.11 GAP92779.1 - 2.2e-19 70.1 0.0 2.9e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 GAP92779.1 - 0.0037 16.2 0.0 0.0059 15.5 0.0 1.2 1 0 0 1 1 1 1 CsiD TPR_11 PF13414.1 GAP92781.1 - 4e-10 39.1 0.8 1e-06 28.2 0.1 2.2 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 GAP92781.1 - 1.3e-07 30.9 4.6 2e-05 24.1 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAP92781.1 - 5.7e-07 29.6 5.0 2.8e-06 27.4 0.7 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAP92781.1 - 5.2e-06 26.7 0.4 2.2e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAP92781.1 - 5.7e-05 23.6 0.1 5.7e-05 23.6 0.1 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAP92781.1 - 7.9e-05 22.0 0.2 0.014 15.0 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAP92781.1 - 0.00013 21.8 2.2 0.04 13.8 0.0 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAP92781.1 - 0.00079 19.2 2.9 0.0025 17.6 0.4 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAP92781.1 - 0.0049 16.5 0.0 0.23 11.3 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAP92781.1 - 0.0076 16.1 4.3 0.25 11.3 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAP92781.1 - 0.062 13.1 0.3 5.3 7.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAP92781.1 - 0.085 13.3 0.7 1.1 9.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 GAP92781.1 - 0.57 10.7 7.0 0.28 11.7 0.4 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat CFEM PF05730.6 GAP92784.1 - 5.4e-13 48.5 12.6 7.9e-13 48.0 8.7 1.3 1 0 0 1 1 1 1 CFEM domain PT PF04886.7 GAP92784.1 - 5.1e-12 44.9 86.6 1e-06 27.9 19.7 4.4 2 1 1 3 3 3 1 PT repeat DUF605 PF04652.11 GAP92784.1 - 2.2 7.6 21.8 2.7 7.2 15.1 1.1 1 0 0 1 1 1 0 Vta1 like Hamartin PF04388.7 GAP92784.1 - 5.7 5.4 16.2 6.6 5.2 11.2 1.1 1 0 0 1 1 1 0 Hamartin protein DUF89 PF01937.14 GAP92785.1 - 3.7e-114 381.2 0.0 4.1e-114 381.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF2207 PF09972.4 GAP92786.1 - 1.9 6.9 3.6 2.1 6.8 2.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) UQ_con PF00179.21 GAP92788.1 - 3.1e-42 143.3 0.0 4e-42 142.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 GAP92788.1 - 1e-06 28.2 0.1 1.8e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain RWD PF05773.17 GAP92788.1 - 0.14 12.0 0.2 0.27 11.1 0.1 1.6 1 1 0 1 1 1 0 RWD domain Radical_SAM PF04055.16 GAP92789.1 - 1e-15 58.2 0.1 4e-15 56.3 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 GAP92789.1 - 1e-12 47.8 0.1 2.6e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAP92789.1 - 0.11 12.7 0.1 0.3 11.2 0.1 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain CoA_binding PF02629.14 GAP92790.1 - 1.6e-26 92.6 4.3 5.3e-26 90.9 0.6 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 GAP92790.1 - 6.2e-24 84.3 0.3 1e-23 83.6 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 GAP92790.1 - 4e-08 32.9 0.0 7.2e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 GAP92790.1 - 0.0017 18.5 0.0 0.006 16.7 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain AAA PF00004.24 GAP92791.1 - 3.6e-41 140.4 0.0 6.2e-41 139.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAP92791.1 - 5.5e-07 29.7 0.1 0.00019 21.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 GAP92791.1 - 2.1e-06 27.7 0.0 4.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 GAP92791.1 - 1.1e-05 24.4 0.0 1.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 GAP92791.1 - 4e-05 23.3 0.1 0.00013 21.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAP92791.1 - 0.0002 21.3 0.1 0.0011 18.9 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 GAP92791.1 - 0.00034 19.7 0.0 0.00063 18.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 GAP92791.1 - 0.00087 19.2 0.2 0.004 17.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 GAP92791.1 - 0.0021 17.9 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAP92791.1 - 0.0037 18.0 0.2 0.011 16.5 0.2 2.0 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 GAP92791.1 - 0.0049 16.5 0.2 0.35 10.5 0.0 2.6 2 1 1 3 3 3 1 NACHT domain AAA_19 PF13245.1 GAP92791.1 - 0.0054 16.4 0.3 0.015 15.0 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 GAP92791.1 - 0.0067 15.8 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 GAP92791.1 - 0.0074 16.1 0.0 0.022 14.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 GAP92791.1 - 0.0088 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 GAP92791.1 - 0.012 15.8 0.0 0.03 14.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.6 GAP92791.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 GAP92791.1 - 0.016 14.4 2.1 0.21 10.8 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.1 GAP92791.1 - 0.018 14.4 1.7 0.25 10.7 0.3 2.4 1 1 1 2 2 2 0 AAA domain TIP49 PF06068.8 GAP92791.1 - 0.021 13.5 0.1 0.045 12.4 0.1 1.5 1 1 0 1 1 1 0 TIP49 C-terminus NB-ARC PF00931.17 GAP92791.1 - 0.04 12.7 0.0 0.064 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain KaiC PF06745.8 GAP92791.1 - 0.042 12.9 0.2 0.44 9.6 0.1 2.2 1 1 1 2 2 2 0 KaiC RNA_helicase PF00910.17 GAP92791.1 - 0.045 13.9 0.0 0.086 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 GAP92791.1 - 0.05 13.1 0.2 0.14 11.7 0.2 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 GAP92791.1 - 0.054 12.6 0.1 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 GAP92791.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF500 PF04366.7 GAP92792.1 - 1.9e-33 114.5 4.8 5.9e-33 112.9 3.3 1.8 1 1 0 1 1 1 1 Family of unknown function (DUF500) HTH_Tnp_Tc5 PF03221.11 GAP92793.1 - 1.6e-14 53.4 0.2 1.6e-14 53.4 0.1 3.1 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DUF490 PF04357.8 GAP92793.1 - 0.037 13.1 1.2 0.067 12.2 0.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF490) ROK PF00480.15 GAP92793.1 - 0.082 12.7 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 ROK family DUF4407 PF14362.1 GAP92793.1 - 0.16 10.9 4.8 1.6 7.6 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PAT1 PF09770.4 GAP92793.1 - 0.29 9.3 28.7 0.018 13.3 13.6 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF3573 PF12097.3 GAP92793.1 - 0.36 9.3 6.3 0.53 8.8 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) IncA PF04156.9 GAP92793.1 - 0.99 8.9 14.2 24 4.4 0.0 2.2 2 0 0 2 2 2 0 IncA protein BAF1_ABF1 PF04684.8 GAP92793.1 - 1.5 7.6 31.7 2.9 6.6 22.0 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor KfrA_N PF11740.3 GAP92793.1 - 8.7 6.8 32.3 0.069 13.5 4.5 2.9 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term DUF1764 PF08576.5 GAP92793.1 - 9.7 7.0 10.0 2.7 8.8 3.1 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Thymidylat_synt PF00303.14 GAP92794.1 - 1.7e-117 391.2 0.0 1.9e-117 391.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase SH3_1 PF00018.23 GAP92795.1 - 1.3e-27 94.9 0.0 2.3e-13 49.2 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 GAP92795.1 - 2.7e-20 71.6 0.1 6.6e-10 38.4 0.0 2.8 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 GAP92795.1 - 6.8e-14 51.6 0.0 1.5e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 GAP92795.1 - 7.1e-14 51.0 0.0 8.8e-09 34.7 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.19 GAP92795.1 - 2.3e-09 36.7 0.1 3.9e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 PB1 domain Rad60-SLD PF11976.3 GAP92795.1 - 0.093 12.4 0.1 0.093 12.4 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like HATPase_c_3 PF13589.1 GAP92796.1 - 0.065 12.8 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SAC3_GANP PF03399.11 GAP92797.1 - 1.7e-63 213.8 2.1 2.8e-63 213.1 1.5 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 GAP92797.1 - 0.013 15.2 0.4 0.041 13.6 0.0 1.9 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 EAP30 PF04157.11 GAP92798.1 - 2.8e-56 190.1 0.0 3.7e-56 189.7 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 GAP92798.1 - 2.8e-25 87.9 0.0 4.6e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.13 GAP92798.1 - 0.00052 19.0 0.8 0.00052 19.0 0.5 2.6 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others GRAM PF02893.15 GAP92798.1 - 0.0022 17.4 0.0 0.0052 16.2 0.0 1.6 1 0 0 1 1 1 1 GRAM domain zf-Sec23_Sec24 PF04810.10 GAP92798.1 - 0.0061 16.0 6.6 0.017 14.7 0.5 2.5 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Amidase_2 PF01510.20 GAP92798.1 - 0.15 12.1 0.0 0.56 10.2 0.0 1.8 1 1 0 2 2 2 0 N-acetylmuramoyl-L-alanine amidase DZR PF12773.2 GAP92798.1 - 4.9 7.0 10.0 0.15 11.9 0.4 2.8 3 1 0 3 3 3 0 Double zinc ribbon DUF3439 PF11921.3 GAP92799.1 - 0.024 14.3 9.6 0.051 13.3 6.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Peptidase_S9 PF00326.16 GAP92800.1 - 2.6e-39 134.6 0.0 4.4e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAP92800.1 - 7.2e-13 48.5 0.0 1.2e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 GAP92800.1 - 1.1e-06 27.3 0.0 0.00021 19.9 0.0 2.7 3 0 0 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.2 GAP92800.1 - 2.1e-06 27.7 2.6 3.6e-05 23.7 0.5 2.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 GAP92800.1 - 0.0013 18.2 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase PD40 PF07676.7 GAP92800.1 - 0.0025 17.4 0.1 0.32 10.7 0.0 2.8 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat DUF2920 PF11144.3 GAP92800.1 - 0.11 11.4 0.2 7.6 5.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) PLDc_2 PF13091.1 GAP92802.1 - 4.4e-18 65.2 0.0 9.1e-10 38.3 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain Regulator_TrmB PF11495.3 GAP92802.1 - 0.059 12.3 0.0 0.3 10.0 0.0 2.0 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB PLDc PF00614.17 GAP92802.1 - 0.063 13.1 0.2 12 5.8 0.0 2.6 2 0 0 2 2 2 0 Phospholipase D Active site motif Peptidase_M28 PF04389.12 GAP92803.1 - 1.3e-23 83.6 0.0 2.2e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 GAP92803.1 - 1.2e-05 24.8 0.0 2.5e-05 23.8 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Aminotran_3 PF00202.16 GAP92806.1 - 6.7e-86 288.1 0.0 7.9e-86 287.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 GAP92806.1 - 0.11 11.3 0.0 0.26 10.2 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class I and II Exo70 PF03081.10 GAP92807.1 - 3.4e-69 233.4 0.1 7.8e-69 232.2 0.0 1.6 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Baculo_PEP_C PF04513.7 GAP92807.1 - 0.0002 21.1 10.6 0.075 12.8 0.5 4.4 4 0 0 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus HbrB PF08539.6 GAP92807.1 - 0.066 13.0 1.7 20 5.0 0.1 3.3 3 0 0 3 3 3 0 HbrB-like Syntaxin PF00804.20 GAP92807.1 - 0.43 10.7 11.7 6.9 6.8 0.4 4.7 3 2 0 4 4 4 0 Syntaxin IncA PF04156.9 GAP92807.1 - 2.8 7.4 10.7 5.7 6.4 3.1 2.9 3 0 0 3 3 3 0 IncA protein NPV_P10 PF05531.7 GAP92807.1 - 3.7 7.8 8.3 4.3 7.6 0.1 3.9 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF1517 PF07466.6 GAP92808.1 - 0.0095 14.9 4.0 0.014 14.3 2.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1517) DUF912 PF06024.7 GAP92808.1 - 0.029 14.3 0.0 0.069 13.1 0.0 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Herpes_gE PF02480.11 GAP92808.1 - 0.036 12.3 0.0 0.048 11.9 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E YajC PF02699.10 GAP92808.1 - 0.048 13.3 0.1 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit Mucin PF01456.12 GAP92808.1 - 0.19 11.4 12.8 0.072 12.8 7.2 1.4 1 1 0 1 1 1 0 Mucin-like glycoprotein RCR PF12273.3 GAP92808.1 - 0.21 12.1 0.0 0.21 12.1 0.0 2.3 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red FixQ PF05545.6 GAP92808.1 - 0.29 10.7 1.3 0.62 9.7 0.9 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ SOG2 PF10428.4 GAP92808.1 - 0.48 9.0 3.7 0.55 8.8 2.5 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein IBR PF01485.16 GAP92810.1 - 4.2e-15 55.3 43.5 1.3e-09 37.7 6.3 3.7 3 1 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 GAP92810.1 - 0.0025 17.5 6.2 0.0025 17.5 4.3 3.5 3 0 0 3 3 3 1 Ring finger domain DUF676 PF05057.9 GAP92811.1 - 2.9e-41 141.1 0.0 6.9e-32 110.5 0.0 3.2 1 1 1 2 2 2 2 Putative serine esterase (DUF676) PGAP1 PF07819.8 GAP92811.1 - 0.0061 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 GAP92811.1 - 0.029 14.0 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.6 GAP92811.1 - 0.052 12.6 0.0 0.086 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Bromodomain PF00439.20 GAP92812.1 - 8.8e-21 73.6 0.0 1.5e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain BTB PF00651.26 GAP92812.1 - 3.4e-06 27.0 0.1 1.2e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Carb_bind PF10645.4 GAP92813.1 - 3.2e-07 30.0 4.4 6.3e-07 29.1 3.1 1.5 1 0 0 1 1 1 1 Carbohydrate binding GDE_C PF06202.9 GAP92813.1 - 0.041 12.6 0.1 2.5 6.7 0.0 2.9 3 1 0 3 3 3 0 Amylo-alpha-1,6-glucosidase RecA PF00154.16 GAP92814.1 - 4.8e-06 25.8 0.0 1.2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 GAP92814.1 - 2.2e-05 23.9 0.0 0.00039 19.8 0.0 2.4 2 1 1 3 3 3 1 AAA domain KaiC PF06745.8 GAP92814.1 - 4.8e-05 22.5 0.0 8e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_10 PF12846.2 GAP92814.1 - 6e-05 22.6 0.0 8.3e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain IstB_IS21 PF01695.12 GAP92814.1 - 0.00041 19.8 0.1 0.0013 18.1 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.1 GAP92814.1 - 0.00042 20.0 0.0 0.0014 18.3 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain DnaB_C PF03796.10 GAP92814.1 - 0.0037 16.1 0.2 0.027 13.3 0.0 2.0 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_33 PF13671.1 GAP92814.1 - 0.023 14.5 0.0 0.042 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 GAP92814.1 - 0.029 14.0 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 GAP92814.1 - 0.09 12.7 0.0 0.27 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain KTI12 PF08433.5 GAP92814.1 - 0.1 11.7 0.0 0.22 10.6 0.0 1.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_17 PF13207.1 GAP92814.1 - 0.11 13.3 0.0 0.29 11.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain GIDA PF01134.17 GAP92814.1 - 0.11 11.3 0.0 2.7 6.7 0.0 2.1 1 1 0 1 1 1 0 Glucose inhibited division protein A AAA PF00004.24 GAP92814.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-H2C2_2 PF13465.1 GAP92815.1 - 4.5e-09 36.1 20.7 1.8e-05 24.7 2.3 4.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 GAP92815.1 - 2.2e-05 24.5 12.5 0.0011 19.1 2.9 3.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP92815.1 - 0.00018 21.5 17.2 0.035 14.4 2.7 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger SNF2_N PF00176.18 GAP92816.1 - 1.3e-31 109.4 0.0 5.5e-30 104.1 0.0 2.5 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAP92816.1 - 2.3e-10 40.2 0.0 5.1e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 GAP92816.1 - 0.00014 21.5 7.7 0.00033 20.3 5.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.10 GAP92816.1 - 0.00022 21.0 0.0 0.004 16.9 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.1 GAP92816.1 - 0.0005 19.7 3.0 0.0014 18.2 2.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 GAP92816.1 - 0.0011 18.5 7.5 0.0012 18.4 4.1 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 GAP92816.1 - 0.0049 16.3 0.0 0.024 14.1 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.1 GAP92816.1 - 0.017 14.9 5.5 0.017 14.9 3.8 1.8 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_4 PF15227.1 GAP92816.1 - 0.029 14.2 8.3 0.066 13.1 5.7 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 GAP92816.1 - 0.1 12.1 3.5 0.29 10.7 2.5 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.1 GAP92816.1 - 0.13 12.3 7.9 0.32 11.0 5.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-CHY PF05495.7 GAP92816.1 - 0.3 11.2 9.1 0.84 9.8 6.3 1.8 1 1 0 1 1 1 0 CHY zinc finger DZR PF12773.2 GAP92816.1 - 0.73 9.6 10.4 17 5.3 7.2 2.4 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.1 GAP92816.1 - 0.75 9.4 8.2 1.7 8.2 5.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE PF01363.16 GAP92816.1 - 1.6 8.7 6.4 5.6 6.9 4.5 2.0 1 1 0 1 1 1 0 FYVE zinc finger AAT PF03417.11 GAP92817.1 - 1.9e-30 106.0 0.0 2.3e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 GAP92817.1 - 0.005 17.1 0.0 0.009 16.3 0.0 1.4 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase GST_N PF02798.15 GAP92818.1 - 4e-12 46.1 0.0 8.5e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAP92818.1 - 6.1e-12 45.5 0.1 1.5e-11 44.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAP92818.1 - 1.7e-10 40.7 0.1 4.7e-10 39.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAP92818.1 - 7.2e-09 35.5 0.0 1.2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAP92818.1 - 2.7e-07 31.0 0.0 3.8e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAP92818.1 - 1.1e-06 28.4 0.0 2.1e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SPX PF03105.14 GAP92819.1 - 3.3e-47 161.5 0.3 1.5e-46 159.4 0.0 2.2 2 1 0 2 2 2 1 SPX domain Na_sulph_symp PF00939.14 GAP92819.1 - 1.3e-32 113.3 36.9 2.2e-32 112.5 25.6 1.4 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 GAP92819.1 - 7.2e-16 57.6 40.7 3.2e-13 49.0 13.2 2.5 1 1 1 2 2 2 2 Citrate transporter Nucleoplasmin PF03066.10 GAP92819.1 - 0.043 13.3 0.8 0.099 12.1 0.6 1.5 1 0 0 1 1 1 0 Nucleoplasmin Vps39_1 PF10366.4 GAP92820.1 - 5.6e-31 106.7 0.0 2.8e-30 104.5 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.17 GAP92820.1 - 2.8e-21 76.1 0.0 6.2e-21 75.0 0.0 1.5 1 1 0 1 1 1 1 CNH domain Vps39_2 PF10367.4 GAP92820.1 - 6.2e-13 48.8 0.0 1.8e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 GAP92820.1 - 0.016 14.8 0.3 0.016 14.8 0.2 2.2 3 0 0 3 3 3 0 Region in Clathrin and VPS Apc3 PF12895.2 GAP92820.1 - 0.032 14.3 3.0 0.76 9.9 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 GAP92820.1 - 0.5 10.0 3.3 42 3.9 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 GAP92820.1 - 1.5 8.5 3.2 5.9 6.6 0.1 3.3 4 0 0 4 4 4 0 TPR repeat TPR_12 PF13424.1 GAP92820.1 - 2.5 8.1 6.0 11 6.0 0.0 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat Gon7 PF08738.5 GAP92821.1 - 6.9e-12 45.2 12.1 1.2e-10 41.2 8.4 2.5 1 1 0 1 1 1 1 Gon7 family OmpH PF03938.9 GAP92821.1 - 0.013 15.4 3.9 0.015 15.2 2.7 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CBFNT PF08143.6 GAP92821.1 - 0.28 12.3 9.8 0.4 11.8 6.8 1.2 1 0 0 1 1 1 0 CBFNT (NUC161) domain Peptidase_M28 PF04389.12 GAP92822.1 - 4.6e-34 117.7 0.1 9.5e-34 116.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 GAP92822.1 - 7.4e-08 32.1 0.0 1.6e-07 31.0 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 GAP92822.1 - 0.00014 20.7 0.0 0.043 12.5 0.0 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Nicastrin PF05450.10 GAP92822.1 - 0.00015 21.1 0.9 0.00024 20.4 0.0 1.7 2 0 0 2 2 2 1 Nicastrin HbrB PF08539.6 GAP92823.1 - 1.2e-53 181.1 0.0 2.5e-53 180.1 0.0 1.5 1 0 0 1 1 1 1 HbrB-like SprA-related PF12118.3 GAP92823.1 - 0.052 12.8 30.5 0.0059 15.9 17.3 2.0 2 0 0 2 2 2 0 SprA-related family X PF00739.14 GAP92823.1 - 0.093 12.6 0.4 12 5.8 0.0 3.3 2 0 0 2 2 2 0 Trans-activation protein X AvrE PF11725.3 GAP92823.1 - 1.9 5.3 15.5 2.9 4.8 10.8 1.2 1 0 0 1 1 1 0 Pathogenicity factor SelP_N PF04592.9 GAP92823.1 - 2.8 7.2 21.6 1 8.7 0.6 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Cupin_5 PF06172.6 GAP92824.1 - 6.4e-42 142.7 0.0 7.4e-42 142.5 0.0 1.0 1 0 0 1 1 1 1 Cupin superfamily (DUF985) LIM_bind PF01803.11 GAP92825.1 - 5.8e-73 244.9 0.9 5.8e-73 244.9 0.6 5.7 2 1 1 4 4 4 1 LIM-domain binding protein DUF336 PF03928.9 GAP92826.1 - 4.5e-18 65.3 2.3 7.7e-18 64.5 1.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF336) DAP10 PF07213.6 GAP92826.1 - 0.084 12.6 0.2 0.22 11.3 0.1 1.7 1 0 0 1 1 1 0 DAP10 membrane protein Atg8 PF02991.11 GAP92827.1 - 2.5e-51 171.9 0.2 2.9e-51 171.7 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 GAP92827.1 - 2.6e-06 27.5 0.0 3.1e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Coatomer_WDAD PF04053.9 GAP92829.1 - 0.3 9.8 0.0 0.46 9.2 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region PPTA PF01239.17 GAP92830.1 - 1.3e-30 103.3 15.9 7.3e-08 31.4 0.3 6.1 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Med3 PF11593.3 GAP92830.1 - 4.8 6.3 11.2 6.6 5.8 7.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Rxt3 PF08642.5 GAP92833.1 - 8.9e-31 106.5 0.1 4.8e-30 104.1 0.0 2.2 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 GAP92833.1 - 2.3e-07 30.7 0.0 3.5e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 LCCL domain Zip PF02535.17 GAP92833.1 - 0.012 14.6 3.0 0.025 13.5 2.1 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Trp_syntA PF00290.15 GAP92834.1 - 2.5e-92 308.0 0.7 3.3e-92 307.6 0.1 1.6 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.20 GAP92834.1 - 1.6e-43 149.1 0.6 1.6e-43 149.1 0.4 2.1 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Ribosomal_L28 PF00830.14 GAP92836.1 - 2.3e-14 52.9 0.0 3.1e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal L28 family Suf PF05843.9 GAP92837.1 - 0.012 15.3 2.9 0.017 14.8 2.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2756 PF10956.3 GAP92837.1 - 0.24 11.6 9.1 0.48 10.7 6.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) Aminotran_1_2 PF00155.16 GAP92838.1 - 5.2e-27 94.7 0.0 6.8e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II RE_NgoFVII PF09565.5 GAP92838.1 - 0.098 11.5 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 NgoFVII restriction endonuclease Stn1_C PF12659.2 GAP92839.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Telomere capping C-terminal wHTH Herpes_gE PF02480.11 GAP92840.1 - 0.05 11.8 0.0 0.084 11.1 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E NfeD PF01957.13 GAP92840.1 - 0.11 12.6 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding TMEM154 PF15102.1 GAP92840.1 - 0.84 9.3 0.0 0.84 9.3 0.0 2.9 2 1 0 2 2 2 0 TMEM154 protein family HET PF06985.6 GAP92841.1 - 5.2e-18 65.5 2.1 6.2e-18 65.2 1.5 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 GAP92842.1 - 3.2e-114 373.5 18.6 3.6e-17 62.4 0.1 14.0 5 3 10 16 16 16 14 Ankyrin repeats (3 copies) Ank PF00023.25 GAP92842.1 - 2.1e-88 286.0 36.9 1.2e-09 37.4 0.0 25.0 25 2 0 25 25 25 17 Ankyrin repeat Ank_4 PF13637.1 GAP92842.1 - 8.3e-79 258.7 15.6 7.8e-13 48.5 0.0 17.0 11 4 8 20 20 20 13 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP92842.1 - 1.9e-72 231.9 18.8 1.8e-05 24.5 0.0 25.2 24 2 2 26 26 26 13 Ankyrin repeat Ank_5 PF13857.1 GAP92842.1 - 4.9e-69 226.7 26.6 1.2e-09 38.1 0.1 20.4 9 7 12 21 21 21 14 Ankyrin repeats (many copies) PC4 PF02229.11 GAP92843.1 - 6e-20 70.2 0.0 6e-20 70.2 0.0 1.9 3 0 0 3 3 3 1 Transcriptional Coactivator p15 (PC4) SART-1 PF03343.8 GAP92843.1 - 0.0012 17.2 2.5 0.0012 17.2 1.8 1.9 1 1 1 2 2 2 1 SART-1 family YqfQ PF14181.1 GAP92843.1 - 0.64 10.0 6.7 0.37 10.8 0.6 2.1 2 0 0 2 2 2 0 YqfQ-like protein NST1 PF13945.1 GAP92843.1 - 4.3 7.3 8.8 1.6 8.7 1.8 2.1 2 0 0 2 2 2 0 Salt tolerance down-regulator PXA PF02194.10 GAP92844.1 - 1.6e-36 125.5 0.2 4.2e-36 124.2 0.0 1.9 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 GAP92844.1 - 2.7e-19 69.3 0.0 6.9e-19 68.0 0.0 1.8 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 GAP92844.1 - 0.00025 20.8 0.0 0.00087 19.0 0.0 1.9 1 0 0 1 1 1 1 PX domain RIP PF00161.14 GAP92844.1 - 0.056 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Ribosome inactivating protein Hydantoinase_B PF02538.9 GAP92845.1 - 1.5e-201 670.2 0.1 2.9e-199 662.6 0.1 2.1 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 GAP92845.1 - 1.2e-93 313.3 0.8 2.5e-93 312.3 0.5 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 GAP92845.1 - 1.8e-59 200.1 1.2 7.6e-58 194.8 0.1 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region tRNA-synt_2b PF00587.20 GAP92846.1 - 3.9e-30 104.6 0.0 5.6e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 GAP92846.1 - 1.1e-14 54.3 3.8 1.6e-14 53.8 1.5 2.1 3 0 0 3 3 3 1 Seryl-tRNA synthetase N-terminal domain DUF2458 PF10454.4 GAP92846.1 - 0.044 13.6 3.4 0.066 13.0 0.3 2.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2458) NAGLU PF05089.7 GAP92847.1 - 5.3e-129 429.7 4.7 7.6e-129 429.2 3.3 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 GAP92847.1 - 1.6e-60 204.7 0.0 9.8e-38 130.0 2.0 2.8 2 1 1 3 3 3 2 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.2 GAP92847.1 - 2.4e-17 62.3 0.3 1.9e-16 59.4 0.0 2.5 2 1 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain PAF-AH_p_II PF03403.8 GAP92849.1 - 4.1e-10 38.5 0.0 4.9e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 GAP92849.1 - 1.8e-06 27.7 0.2 2.8e-06 27.1 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP92849.1 - 9e-05 22.4 0.8 0.00015 21.6 0.6 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP92849.1 - 0.0021 17.6 0.0 0.0046 16.5 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 GAP92849.1 - 0.03 13.9 0.1 0.051 13.1 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S9 PF00326.16 GAP92849.1 - 0.06 12.5 0.0 0.08 12.1 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family PI-PLC-X PF00388.14 GAP92851.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain NFRKB_winged PF14465.1 GAP92851.1 - 0.1 12.4 0.0 0.82 9.5 0.0 2.2 1 1 1 2 2 2 0 NFRKB Winged Helix-like DUF3533 PF12051.3 GAP92851.1 - 0.53 8.9 7.4 0.74 8.4 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) SUR7 PF06687.7 GAP92852.1 - 1.4e-37 129.3 11.9 1.6e-37 129.1 8.2 1.0 1 0 0 1 1 1 1 SUR7/PalI family DWNN PF08783.6 GAP92853.1 - 1.5e-29 101.6 0.0 2.8e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 GAP92853.1 - 0.00012 21.4 3.6 0.00038 19.8 2.5 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 GAP92853.1 - 0.0033 17.2 1.7 0.0059 16.4 1.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-RING_6 PF14835.1 GAP92853.1 - 0.0081 15.9 1.8 0.015 15.1 1.2 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein U-box PF04564.10 GAP92853.1 - 0.015 15.2 0.1 0.058 13.3 0.0 2.1 2 0 0 2 2 2 0 U-box domain zf-CCHC_3 PF13917.1 GAP92853.1 - 0.023 14.3 0.1 0.052 13.2 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Hanta_G1 PF01567.11 GAP92853.1 - 0.13 10.5 0.3 0.2 9.9 0.2 1.1 1 0 0 1 1 1 0 Hantavirus glycoprotein G1 zf-RING_4 PF14570.1 GAP92853.1 - 0.18 11.4 5.7 0.38 10.3 3.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE_2 PF02318.11 GAP92853.1 - 0.38 10.6 2.2 0.42 10.5 0.6 1.7 2 0 0 2 2 2 0 FYVE-type zinc finger zf-C3HC4_2 PF13923.1 GAP92853.1 - 4.5 7.3 14.2 0.4 10.7 5.7 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF4614 PF15391.1 GAP92854.1 - 2.1 8.0 15.0 1.8 8.3 2.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) HD PF01966.17 GAP92855.1 - 8.5e-06 25.7 2.2 1.3e-05 25.1 0.8 1.9 2 1 0 2 2 2 1 HD domain F-box-like PF12937.2 GAP92856.1 - 0.0044 16.7 0.0 0.012 15.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAP92856.1 - 0.051 13.2 0.2 0.051 13.2 0.1 2.6 2 0 0 2 2 2 0 F-box domain CDC14 PF08045.6 GAP92858.1 - 2.2e-89 298.9 0.0 2.5e-89 298.7 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component polyprenyl_synt PF00348.12 GAP92860.1 - 3.6e-59 199.7 0.0 4.6e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Collagen PF01391.13 GAP92860.1 - 0.079 12.5 1.3 0.15 11.6 0.9 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) DUF4593 PF15263.1 GAP92860.1 - 0.5 10.2 5.5 0.82 9.5 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4593) Coatomer_E PF04733.9 GAP92861.1 - 3.3e-64 216.8 5.6 3.7e-64 216.6 3.9 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 GAP92861.1 - 7e-08 32.6 20.5 0.0034 17.6 0.2 4.0 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAP92861.1 - 1.4e-07 30.9 4.8 0.0024 17.6 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAP92861.1 - 1.8e-06 28.0 20.2 0.0019 18.6 0.2 5.7 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAP92861.1 - 4.2e-06 26.1 1.9 0.049 13.2 0.0 4.5 6 0 0 6 6 5 1 Tetratricopeptide repeat Type_III_YscG PF09477.5 GAP92861.1 - 5.5e-06 26.4 2.6 0.26 11.3 0.1 3.5 2 2 1 3 3 3 2 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_11 PF13414.1 GAP92861.1 - 6e-06 25.8 1.5 0.0018 17.8 0.0 3.9 4 1 0 4 4 4 1 TPR repeat TPR_8 PF13181.1 GAP92861.1 - 4.1e-05 23.0 0.5 0.044 13.5 0.0 4.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAP92861.1 - 0.00012 21.5 5.9 12 5.9 0.1 6.2 6 1 1 7 7 6 0 Tetratricopeptide repeat TPR_15 PF13429.1 GAP92861.1 - 0.00015 20.8 5.2 0.0036 16.4 0.3 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 GAP92861.1 - 0.00018 21.5 1.2 2.1 8.5 0.1 3.8 2 2 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 GAP92861.1 - 0.0013 19.0 6.6 0.57 10.7 0.0 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAP92861.1 - 0.0017 18.9 20.3 0.0089 16.6 0.2 4.9 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAP92861.1 - 0.0024 17.7 9.3 0.062 13.2 0.0 4.7 4 1 2 6 6 6 1 Tetratricopeptide repeat Smr PF01713.16 GAP92861.1 - 0.01 16.0 0.1 0.028 14.6 0.0 1.8 2 0 0 2 2 1 0 Smr domain TPR_17 PF13431.1 GAP92861.1 - 0.013 15.6 2.5 2.8 8.3 0.0 4.7 6 0 0 6 6 4 0 Tetratricopeptide repeat Esterase_phd PF10503.4 GAP92861.1 - 0.027 13.6 0.5 0.045 12.9 0.3 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Apc5 PF12862.2 GAP92861.1 - 0.035 13.9 3.2 1.9 8.3 0.1 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_9 PF13371.1 GAP92861.1 - 0.097 12.5 0.5 0.097 12.5 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 GAP92861.1 - 1.1 9.9 25.2 0.77 10.3 1.5 5.8 7 0 0 7 7 5 0 Tetratricopeptide repeat ATP-synt_DE PF00401.15 GAP92861.1 - 3.6 7.5 11.2 5.2 7.0 0.6 3.4 2 1 1 3 3 3 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain IATP PF04568.7 GAP92862.1 - 1.2 9.1 6.2 0.17 11.9 0.4 2.3 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Fungal_trans PF04082.13 GAP92863.1 - 5.1e-06 25.5 0.4 9.4e-06 24.6 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Kinetocho_Slk19 PF12709.2 GAP92864.1 - 1.7e-19 69.6 1.5 1.7e-19 69.6 1.1 4.1 4 0 0 4 4 4 2 Central kinetochore-associated Mucin PF01456.12 GAP92864.1 - 0.02 14.6 0.4 0.02 14.6 0.3 3.3 5 0 0 5 5 5 0 Mucin-like glycoprotein FlaC_arch PF05377.6 GAP92864.1 - 0.13 12.1 8.7 0.3 11.0 0.4 3.8 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.5 GAP92864.1 - 5 7.2 12.9 18 5.4 1.1 4.2 3 2 0 4 4 4 0 Fibrinogen alpha/beta chain family Rhomboid PF01694.17 GAP92865.1 - 5.2e-15 55.7 7.7 9e-15 54.9 5.3 1.3 1 0 0 1 1 1 1 Rhomboid family PTS_2-RNA PF01885.11 GAP92866.1 - 2e-11 43.5 0.0 3.4e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family zf-C4_Topoisom PF01396.14 GAP92867.1 - 0.045 13.2 0.1 0.099 12.1 0.1 1.5 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger ATX_III PF08098.6 GAP92867.1 - 2.5 8.0 8.6 0.37 10.6 0.5 2.5 2 0 0 2 2 2 0 Anemonia sulcata toxin III family NAP PF00956.13 GAP92869.1 - 4e-35 121.0 1.2 4e-35 121.0 0.8 1.5 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Voldacs PF03517.8 GAP92869.1 - 0.011 15.6 4.7 0.014 15.1 3.2 1.3 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Reductase_C PF14759.1 GAP92869.1 - 0.075 13.3 0.1 0.26 11.6 0.0 2.0 2 0 0 2 2 2 0 Reductase C-terminal F-box-like PF12937.2 GAP92870.1 - 5.8e-08 32.3 0.0 1.3e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAP92870.1 - 8.7e-05 22.0 0.0 0.00051 19.6 0.0 2.2 2 0 0 2 2 2 1 F-box domain Peptidase_A6 PF01829.11 GAP92870.1 - 0.022 13.7 0.0 0.031 13.3 0.0 1.1 1 0 0 1 1 1 0 Peptidase A6 family Hexapep PF00132.19 GAP92871.1 - 1.2e-07 30.8 8.4 0.00019 20.7 1.6 4.3 3 1 2 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 GAP92871.1 - 0.00027 20.4 6.5 0.00031 20.2 0.5 3.1 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 GAP92871.1 - 0.14 10.6 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase Chromo PF00385.19 GAP92874.1 - 7.1e-09 35.2 0.1 1.4e-08 34.2 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Rick_17kDa_Anti PF05433.10 GAP92875.1 - 0.00075 19.1 9.6 0.0025 17.4 0.2 2.4 2 0 0 2 2 2 2 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 GAP92875.1 - 0.0042 16.6 1.6 0.37 10.4 0.0 2.3 2 0 0 2 2 2 2 Glycine zipper Gly-zipper_OmpA PF13436.1 GAP92875.1 - 0.048 13.3 0.2 0.048 13.3 0.1 2.2 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_YMGG PF13441.1 GAP92875.1 - 0.092 12.2 6.4 0.41 10.2 4.4 2.0 1 1 0 1 1 1 0 YMGG-like Gly-zipper zf-CCCH PF00642.19 GAP92877.1 - 0.0045 16.6 3.7 0.0045 16.6 2.6 2.7 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2205 PF10224.4 GAP92877.1 - 1.1 8.9 4.9 0.39 10.3 0.5 2.4 2 1 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Esterase_phd PF10503.4 GAP92878.1 - 4.6e-21 75.0 0.1 6.4e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 GAP92878.1 - 2.5e-07 30.1 0.3 5.1e-07 29.1 0.2 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 GAP92878.1 - 1e-05 25.1 0.3 2.8e-05 23.7 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAP92878.1 - 2.4e-05 24.1 0.1 3.2e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP92878.1 - 4.4e-05 23.4 0.1 0.00012 22.0 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 GAP92878.1 - 0.021 14.2 0.1 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 GAP92878.1 - 0.026 14.0 0.1 0.04 13.4 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 GAP92878.1 - 0.076 12.4 3.7 0.1 12.0 2.6 1.5 1 1 0 1 1 1 0 Putative esterase AXE1 PF05448.7 GAP92878.1 - 0.11 10.9 0.2 0.26 9.7 0.0 1.6 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Zn_clus PF00172.13 GAP92879.1 - 2.5e-07 30.4 10.9 4.1e-07 29.8 7.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ORC5_C PF14630.1 GAP92880.1 - 9.9e-70 235.0 0.0 8.9e-69 231.9 0.0 2.0 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 GAP92880.1 - 4.9e-14 52.7 0.1 1.5e-13 51.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 GAP92880.1 - 0.0029 17.2 0.0 0.0059 16.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAP92880.1 - 0.0035 17.4 0.0 0.0081 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 GAP92880.1 - 0.14 12.6 0.0 0.8 10.2 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein Arch_ATPase PF01637.13 GAP92880.1 - 0.16 11.6 0.0 0.41 10.2 0.0 1.6 2 1 0 2 2 2 0 Archaeal ATPase TrwB_AAD_bind PF10412.4 GAP92880.1 - 0.2 10.2 0.0 0.33 9.5 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Alpha-amylase_C PF02806.13 GAP92881.1 - 6.8e-25 87.0 0.0 1.7e-24 85.7 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 GAP92881.1 - 4.8e-19 68.8 0.3 3e-15 56.4 0.0 2.5 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 GAP92881.1 - 2.2e-16 59.6 0.0 6e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Cellulase PF00150.13 GAP92881.1 - 0.047 12.8 0.0 0.079 12.1 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) hDGE_amylase PF14701.1 GAP92881.1 - 0.059 12.2 0.1 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme AAA_2 PF07724.9 GAP92882.1 - 2.5e-35 121.9 0.0 1.1e-34 119.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 GAP92882.1 - 1.3e-13 51.2 0.3 2.7e-13 50.2 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAP92882.1 - 3.1e-08 33.4 0.0 8e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.4 GAP92882.1 - 1.2e-07 31.5 0.0 2.8e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein MCM PF00493.18 GAP92882.1 - 2.8e-05 23.0 0.6 0.00022 20.1 0.0 2.1 2 0 0 2 2 2 1 MCM2/3/5 family AAA_17 PF13207.1 GAP92882.1 - 4.9e-05 24.1 0.7 8.8e-05 23.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 GAP92882.1 - 0.00019 21.5 0.0 0.0015 18.5 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 GAP92882.1 - 0.00024 20.9 0.0 0.00048 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAP92882.1 - 0.001 19.2 0.1 0.0046 17.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 GAP92882.1 - 0.0021 17.4 0.0 0.0045 16.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein T2SE PF00437.15 GAP92882.1 - 0.0086 14.9 0.0 0.017 13.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 GAP92882.1 - 0.019 14.7 2.1 0.31 10.8 0.0 2.4 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.1 GAP92882.1 - 0.032 14.5 0.2 0.032 14.5 0.2 2.0 2 1 0 2 2 1 0 AAA domain Sigma54_activat PF00158.21 GAP92882.1 - 0.056 12.9 0.0 0.37 10.2 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_23 PF13476.1 GAP92882.1 - 0.083 13.1 0.4 1.3 9.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 GAP92882.1 - 0.091 11.9 0.0 2 7.5 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 GAP92882.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 GAP92882.1 - 0.12 12.7 0.8 0.18 12.0 0.0 1.7 2 0 0 2 2 1 0 ABC transporter KAP_NTPase PF07693.9 GAP92882.1 - 0.2 10.6 0.1 0.39 9.6 0.0 1.4 2 0 0 2 2 2 0 KAP family P-loop domain COX4 PF02936.9 GAP92883.1 - 3.9e-48 162.7 0.0 4.6e-48 162.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Mus7 PF09462.5 GAP92884.1 - 4.1e-115 385.9 2.4 6.4e-115 385.3 1.7 1.3 1 0 0 1 1 1 1 Mus7/MMS22 family DUF3425 PF11905.3 GAP92885.1 - 2.8e-10 40.2 0.0 4e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Abhydrolase_5 PF12695.2 GAP92886.1 - 6.1e-10 39.0 0.0 1.3e-09 37.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP92886.1 - 5.6e-07 29.6 3.4 1.4e-06 28.3 2.2 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 GAP92886.1 - 1.3e-06 28.0 0.3 1.8e-06 27.5 0.2 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 GAP92886.1 - 0.0012 18.1 0.2 0.0035 16.6 0.1 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.7 GAP92886.1 - 0.1 11.0 0.1 0.2 10.1 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) COesterase PF00135.23 GAP92887.1 - 1.4e-85 288.0 0.1 2.3e-79 267.5 0.2 2.2 1 1 1 2 2 2 2 Carboxylesterase family AAA PF00004.24 GAP92887.1 - 2.5e-40 137.7 0.0 2.4e-39 134.5 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Abhydrolase_3 PF07859.8 GAP92887.1 - 1.5e-12 47.5 0.0 4.2e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 alpha/beta hydrolase fold AAA_16 PF13191.1 GAP92887.1 - 8.1e-07 29.2 0.4 0.0012 18.9 0.0 3.6 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 GAP92887.1 - 1.1e-05 24.5 0.0 2.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 GAP92887.1 - 4.1e-05 23.7 0.1 0.0046 17.1 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAP92887.1 - 8.5e-05 23.3 0.1 0.0005 20.8 0.0 2.5 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 GAP92887.1 - 0.00033 20.5 0.0 0.00077 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Abhydrolase_5 PF12695.2 GAP92887.1 - 0.0017 18.1 0.1 0.0045 16.7 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_19 PF13245.1 GAP92887.1 - 0.0063 16.2 0.1 0.021 14.5 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 GAP92887.1 - 0.0075 15.6 0.0 0.023 14.1 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.1 GAP92887.1 - 0.012 15.4 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAP92887.1 - 0.027 14.7 0.0 0.066 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 GAP92887.1 - 0.029 13.7 0.6 1 8.7 0.1 2.6 1 1 1 2 2 2 0 AAA-like domain TIP49 PF06068.8 GAP92887.1 - 0.029 13.0 0.0 0.053 12.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus ATP-synt_ab PF00006.20 GAP92887.1 - 0.032 13.7 0.0 0.068 12.6 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.9 GAP92887.1 - 0.036 13.8 0.0 0.1 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 GAP92887.1 - 0.04 14.0 1.0 0.1 12.7 0.0 2.2 3 0 0 3 3 1 0 RNA helicase AAA_25 PF13481.1 GAP92887.1 - 0.044 13.1 0.4 1.1 8.5 0.1 2.3 1 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 GAP92887.1 - 0.081 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 GAP92887.1 - 0.16 11.5 0.2 0.35 10.4 0.2 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 GAP92887.1 - 0.32 9.9 0.5 1.5 7.7 0.1 2.1 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Ank_2 PF12796.2 GAP92889.1 - 1.1e-49 166.6 0.1 2.3e-11 43.8 0.1 9.1 2 2 4 8 8 8 7 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAP92889.1 - 5.3e-33 109.7 0.5 0.0019 18.2 0.0 12.7 14 0 0 14 14 14 8 Ankyrin repeat Ank PF00023.25 GAP92889.1 - 2.1e-32 109.2 13.7 0.00023 20.8 0.0 13.7 15 0 0 15 15 15 6 Ankyrin repeat Ank_5 PF13857.1 GAP92889.1 - 3.6e-31 106.4 4.9 0.0069 16.6 0.0 12.1 9 3 4 13 13 13 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAP92889.1 - 3.5e-25 87.9 3.9 0.00012 22.4 0.0 10.4 10 1 2 12 12 12 7 Ankyrin repeats (many copies) Clr5 PF14420.1 GAP92889.1 - 2.1e-18 65.9 2.9 4.3e-18 64.9 2.0 1.6 1 0 0 1 1 1 1 Clr5 domain zf-C2H2_4 PF13894.1 GAP92890.1 - 6.3e-05 23.0 18.8 0.7 10.3 0.1 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 GAP92890.1 - 0.016 15.4 23.2 0.4 11.1 0.3 4.6 4 1 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 GAP92890.1 - 0.025 14.6 2.8 0.38 10.9 0.0 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAP92890.1 - 0.16 12.2 3.7 0.84 9.9 0.0 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 GAP92890.1 - 0.49 10.7 0.2 0.49 10.7 0.1 4.4 5 0 0 5 5 5 0 Zinc-finger double domain zf-C2H2_2 PF12756.2 GAP92890.1 - 1.2 9.3 6.6 0.83 9.8 0.3 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Chorismate_synt PF01264.16 GAP92891.1 - 8.4e-130 432.2 0.0 9.9e-130 432.0 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Acetyltransf_1 PF00583.19 GAP92892.1 - 6.8e-11 42.0 0.0 2.8e-10 40.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAP92892.1 - 1.3e-08 34.9 0.1 1.1e-07 31.9 0.0 2.3 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAP92892.1 - 1.6e-06 28.1 0.0 3.2e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAP92892.1 - 7.7e-06 25.7 0.0 1.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAP92892.1 - 0.0005 19.7 0.0 0.0013 18.4 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 GAP92892.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase OPT PF03169.10 GAP92893.1 - 4.4e-97 326.0 33.5 2.8e-96 323.3 23.2 1.8 1 1 0 1 1 1 1 OPT oligopeptide transporter protein Beta-lactamase PF00144.19 GAP92895.1 - 1.8e-43 148.8 0.0 2.7e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 GAP92895.1 - 3.7e-08 33.1 0.0 7.6e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Gal-bind_lectin PF00337.17 GAP92895.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Galactoside-binding lectin TPR_12 PF13424.1 GAP92896.1 - 1.2e-10 41.2 10.9 2.9e-05 23.9 0.2 4.5 2 1 4 6 6 6 5 Tetratricopeptide repeat NB-ARC PF00931.17 GAP92896.1 - 1.3e-10 40.5 0.0 2.4e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.1 GAP92896.1 - 1.1e-06 28.3 2.9 0.11 12.4 0.0 5.5 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAP92896.1 - 2.6e-05 24.7 3.2 0.45 11.2 0.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAP92896.1 - 2.8e-05 24.3 9.7 0.81 10.4 0.1 6.7 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAP92896.1 - 3.8e-05 23.2 8.6 0.003 17.1 2.1 3.8 3 0 0 3 3 3 1 TPR repeat TPR_7 PF13176.1 GAP92896.1 - 0.0001 21.8 2.2 10 6.1 0.1 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat AAA_16 PF13191.1 GAP92896.1 - 0.00012 22.1 1.4 0.0063 16.5 0.1 3.7 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 GAP92896.1 - 0.00045 20.3 0.0 0.0015 18.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain TPR_2 PF07719.12 GAP92896.1 - 0.00097 18.8 12.6 0.9 9.6 0.1 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 GAP92896.1 - 0.013 15.8 5.2 0.23 11.9 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAP92896.1 - 0.1 12.9 2.6 2 8.8 0.3 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAP92896.1 - 0.14 12.0 4.8 35 4.5 0.3 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAP92896.1 - 1.2 8.9 6.1 7.3 6.3 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat GMC_oxred_N PF00732.14 GAP92897.1 - 9.1e-60 202.3 0.0 1.3e-59 201.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase UDPG_MGDP_dh_N PF03721.9 GAP92897.1 - 1e-36 126.0 0.2 1.5e-27 96.1 0.0 3.6 3 1 1 4 4 4 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 GAP92897.1 - 3.5e-32 110.4 0.0 8.4e-32 109.2 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 GAP92897.1 - 3.5e-18 65.7 0.1 5.5e-17 61.8 0.0 2.4 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain GMC_oxred_C PF05199.8 GAP92897.1 - 1.4e-05 25.4 0.0 3.5e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase NAD_Gly3P_dh_N PF01210.18 GAP92897.1 - 0.00044 20.0 0.3 4.3 7.0 0.0 3.4 3 0 0 3 3 3 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.7 GAP92897.1 - 0.00051 19.0 0.0 0.00084 18.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 GAP92897.1 - 0.00053 19.9 0.0 0.0048 16.8 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAP92897.1 - 0.0008 19.3 0.0 0.01 15.7 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 GAP92897.1 - 0.0095 15.9 2.6 0.092 12.7 0.0 3.3 4 0 0 4 4 4 1 TrkA-N domain DAO PF01266.19 GAP92897.1 - 0.019 13.9 0.1 0.12 11.2 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAP92897.1 - 0.025 13.4 0.0 0.045 12.5 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 GAP92897.1 - 0.031 12.7 0.1 0.083 11.3 0.1 1.7 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 GAP92897.1 - 0.038 13.7 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 GAP92897.1 - 0.14 11.2 0.1 0.28 10.2 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Melibiase PF02065.13 GAP92898.1 - 4.2e-13 48.7 0.1 2.3e-09 36.4 0.0 2.8 2 1 0 2 2 2 2 Melibiase ADH_zinc_N_2 PF13602.1 GAP92899.1 - 2.4e-13 51.0 0.0 4.9e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 GAP92899.1 - 1.1e-10 41.1 0.0 2.4e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP92899.1 - 2.1e-05 24.2 0.8 0.0015 18.3 0.0 3.1 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain DFP PF04127.10 GAP92899.1 - 0.034 13.7 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Zn_clus PF00172.13 GAP92901.1 - 7.1e-07 29.0 12.8 1.3e-06 28.1 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAP92901.1 - 1.6e-05 23.6 0.1 2e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RNase_T PF00929.19 GAP92902.1 - 4.3e-17 62.8 0.0 7e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Dsh_C PF12316.3 GAP92902.1 - 7.8 6.5 15.8 0.1 12.6 3.3 2.2 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal HET PF06985.6 GAP92903.1 - 4.3e-23 82.0 0.0 1.2e-22 80.5 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Complex1_LYR_2 PF13233.1 GAP92904.1 - 9.4e-19 67.8 0.2 1.2e-18 67.5 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 GAP92904.1 - 0.0056 16.4 1.0 0.0084 15.8 0.7 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) MMR_HSR1 PF01926.18 GAP92905.1 - 1.1e-18 67.2 0.0 2e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAP92905.1 - 1.5e-05 24.5 0.0 7.4e-05 22.2 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 GAP92905.1 - 0.00016 20.9 0.0 0.00059 19.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 GAP92905.1 - 0.0012 18.6 0.1 0.063 13.1 0.1 2.5 1 1 1 2 2 2 1 Dynamin family Miro PF08477.8 GAP92905.1 - 0.018 15.5 0.0 0.035 14.6 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein FeoB_N PF02421.13 GAP92905.1 - 0.032 13.4 0.0 0.68 9.1 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_17 PF13207.1 GAP92905.1 - 0.1 13.4 0.0 0.28 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 GAP92905.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase zf-DHHC PF01529.15 GAP92906.1 - 5.5e-31 107.2 0.5 9.9e-31 106.4 0.3 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Myb_DNA-bind_2 PF08914.6 GAP92907.1 - 4.4e-28 96.8 3.2 1.1e-19 69.9 0.1 2.7 2 0 0 2 2 2 2 Rap1 Myb domain Rap1_C PF11626.3 GAP92907.1 - 5.8e-19 67.7 0.0 7.8e-18 64.1 0.0 2.5 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Rap1-DNA-bind PF09197.5 GAP92907.1 - 1.5e-10 41.5 0.1 1.1e-06 29.1 0.0 2.9 1 1 1 2 2 2 2 Rap1, DNA-binding ARID PF01388.16 GAP92907.1 - 6.3e-10 38.7 0.0 1.7e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Myb_DNA-bind_6 PF13921.1 GAP92907.1 - 0.00031 20.8 10.1 0.08 13.0 0.3 3.7 4 0 0 4 4 4 2 Myb-like DNA-binding domain GFA PF04828.9 GAP92909.1 - 1.3e-17 63.4 0.0 1.7e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF3431 PF11913.3 GAP92910.1 - 1.8e-10 40.6 0.0 3.4e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) E1-E2_ATPase PF00122.15 GAP92912.1 - 2.2e-50 170.8 0.6 7.7e-49 165.7 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 GAP92912.1 - 1.2e-39 137.0 0.7 3.2e-39 135.5 0.2 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 GAP92912.1 - 1.9e-18 66.3 2.6 1.3e-09 38.0 0.1 3.3 4 0 0 4 4 4 2 Heavy-metal-associated domain HAD PF12710.2 GAP92912.1 - 5.3e-18 65.8 0.0 1.2e-17 64.6 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAP92912.1 - 0.0002 21.0 1.2 0.00059 19.4 1.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase zf-HC2 PF13490.1 GAP92912.1 - 3.7 7.5 7.6 0.2 11.6 1.2 2.0 2 0 0 2 2 2 0 Putative zinc-finger Glyco_hydro_61 PF03443.9 GAP92913.1 - 4.2e-43 147.6 0.0 5e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 zf-C3HC PF07967.8 GAP92914.1 - 4e-40 136.6 0.1 1.5e-33 115.3 0.0 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 GAP92914.1 - 3.5e-26 90.8 2.9 1.5e-25 88.8 0.2 2.6 2 0 0 2 2 2 1 Rsm1-like BIR PF00653.16 GAP92914.1 - 0.00032 21.0 0.2 0.02 15.2 0.1 2.6 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain Inositol_P PF00459.20 GAP92915.1 - 5.2e-51 173.5 1.5 8e-51 172.9 1.1 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family HTH_37 PF13744.1 GAP92915.1 - 0.075 12.8 0.5 8.3 6.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Ribosomal_L6 PF00347.18 GAP92916.1 - 2.5e-19 69.5 0.0 1.2e-11 44.9 0.0 3.5 3 1 0 3 3 3 2 Ribosomal protein L6 Tht1 PF04163.7 GAP92917.1 - 1.1e-06 27.3 2.0 2e-06 26.4 1.4 1.3 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein DUF2884 PF11101.3 GAP92917.1 - 0.01 15.2 0.1 0.01 15.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) Frankia_peptide PF14407.1 GAP92917.1 - 0.039 13.7 0.3 0.21 11.3 0.2 2.3 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. MCR_beta_N PF02783.10 GAP92917.1 - 0.16 11.3 3.9 2.1 7.7 0.9 2.2 1 1 1 2 2 2 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain US22 PF02393.11 GAP92918.1 - 0.098 12.6 0.4 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 US22 like AA_permease PF00324.16 GAP92919.1 - 1.2e-108 363.5 44.8 1.4e-108 363.3 31.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAP92919.1 - 3.7e-27 94.9 49.6 5.4e-27 94.3 34.4 1.2 1 0 0 1 1 1 1 Amino acid permease DUF2665 PF11654.3 GAP92919.1 - 0.032 13.7 0.3 0.1 12.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2665) DIM PF08194.7 GAP92919.1 - 0.039 13.9 0.9 0.25 11.3 0.6 2.4 1 0 0 1 1 1 0 DIM protein DUF3671 PF12420.3 GAP92919.1 - 2.6 8.0 7.4 24 4.9 3.6 2.7 2 0 0 2 2 2 0 Protein of unknown function Methyltransf_23 PF13489.1 GAP92920.1 - 2.7e-17 62.9 0.0 3.4e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP92920.1 - 2.8e-15 56.5 0.0 4e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP92920.1 - 6.5e-14 52.4 0.0 8.7e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP92920.1 - 9.2e-14 51.7 0.0 1.3e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP92920.1 - 8e-13 48.2 0.0 9.2e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP92920.1 - 2.9e-08 33.7 1.5 1.3e-07 31.6 1.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP92920.1 - 5e-06 26.8 0.0 6.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 GAP92920.1 - 0.00011 21.4 0.0 0.00013 21.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 GAP92920.1 - 0.0011 18.3 0.0 0.0023 17.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain CMAS PF02353.15 GAP92920.1 - 0.014 14.4 0.0 0.041 12.9 0.0 1.8 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase DHBP_synthase PF00926.14 GAP92922.1 - 2e-72 242.5 0.0 1.6e-71 239.5 0.0 1.9 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase DUF4439 PF14530.1 GAP92922.1 - 0.032 14.6 0.4 0.052 14.0 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4439) DUF1191 PF06697.7 GAP92924.1 - 0.0048 15.7 0.0 0.0061 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) EcKinase PF02958.15 GAP92925.1 - 1.3e-15 57.3 0.0 7.4e-15 54.8 0.0 2.0 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 GAP92925.1 - 9.6e-09 35.3 4.2 1.9e-08 34.3 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAP92925.1 - 0.12 11.9 0.0 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase NAD_binding_10 PF13460.1 GAP92926.1 - 2.5e-14 53.6 0.8 3.4e-14 53.2 0.6 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAP92926.1 - 1.1e-07 31.5 0.1 2.4e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HIM1 PF08732.5 GAP92926.1 - 5.8e-06 25.0 0.0 1.5e-05 23.7 0.0 1.7 1 1 1 2 2 2 1 HIM1 NAD_binding_4 PF07993.7 GAP92926.1 - 0.00012 21.0 0.1 0.032 13.1 0.0 2.7 2 1 1 3 3 3 1 Male sterility protein NmrA PF05368.8 GAP92926.1 - 0.00015 21.0 0.0 0.00024 20.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 GAP92926.1 - 0.00083 18.1 0.0 0.0012 17.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 GAP92926.1 - 0.0031 17.4 2.7 0.015 15.2 1.1 2.4 2 1 0 2 2 2 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 GAP92926.1 - 0.0046 17.2 0.0 0.011 16.0 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DUF1471 PF07338.8 GAP92926.1 - 0.1 12.2 1.3 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1471) Pyridox_oxidase PF01243.15 GAP92927.1 - 0.00049 20.0 0.0 0.00087 19.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pectinesterase PF01095.14 GAP92929.1 - 5.2e-14 51.5 0.0 1.9e-13 49.6 0.0 2.0 1 1 0 1 1 1 1 Pectinesterase Big_5 PF13205.1 GAP92929.1 - 2.5e-06 28.0 3.5 2.4e-05 24.8 0.7 3.0 2 1 0 2 2 2 1 Bacterial Ig-like domain DUF3328 PF11807.3 GAP92931.1 - 6.1e-47 160.0 0.2 8.3e-47 159.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) TrwB_AAD_bind PF10412.4 GAP92932.1 - 0.021 13.4 0.0 0.029 13.0 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF2116 PF09889.4 GAP92932.1 - 0.051 13.3 0.1 0.28 10.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF3377 PF11857.3 GAP92932.1 - 0.085 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF3328 PF11807.3 GAP92932.1 - 0.26 10.9 5.5 1.4 8.5 3.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) Gemini_mov PF01708.11 GAP92933.1 - 0.45 10.0 6.6 0.19 11.2 2.0 2.2 2 0 0 2 2 2 0 Geminivirus putative movement protein Ank_2 PF12796.2 GAP92934.1 - 2.9e-50 168.5 1.2 3.4e-14 52.9 0.0 5.7 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAP92934.1 - 1.8e-41 137.8 6.6 4.9e-08 32.4 0.1 9.2 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.1 GAP92934.1 - 9.5e-38 127.9 8.4 1.4e-09 38.1 0.0 8.5 5 1 4 9 9 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP92934.1 - 3e-32 109.8 14.2 5.9e-08 32.7 0.1 7.8 4 3 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP92934.1 - 1.1e-30 102.5 2.7 0.00011 22.1 0.0 9.4 9 0 0 9 9 9 6 Ankyrin repeat AAA_16 PF13191.1 GAP92934.1 - 1.1e-07 31.9 0.2 8.1e-07 29.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 GAP92934.1 - 9.3e-05 22.1 0.0 0.00036 20.2 0.0 2.0 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 GAP92934.1 - 0.00098 18.0 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 GAP92934.1 - 0.048 13.8 0.0 0.23 11.5 0.0 2.3 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 GAP92934.1 - 0.085 11.8 1.5 1.4 7.8 0.3 2.2 1 1 1 2 2 2 0 KAP family P-loop domain DUF2075 PF09848.4 GAP92934.1 - 0.23 10.4 0.0 0.37 9.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 GAP92934.1 - 0.27 10.3 0.0 16 4.5 0.0 2.4 2 0 0 2 2 2 0 KaiC NACHT PF05729.7 GAP92935.1 - 6.5e-17 61.6 0.0 2.1e-16 60.0 0.0 2.0 2 0 0 2 2 1 1 NACHT domain HEAT_2 PF13646.1 GAP92935.1 - 3.1e-11 43.3 1.5 0.0033 17.6 0.0 5.5 3 2 2 5 5 5 3 HEAT repeats AAA_18 PF13238.1 GAP92935.1 - 1.2e-06 28.8 0.1 1.6e-05 25.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain PGAP1 PF07819.8 GAP92935.1 - 1.4e-06 28.1 0.0 2.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein AAA_22 PF13401.1 GAP92935.1 - 2e-05 24.7 0.2 0.011 15.8 0.0 4.2 5 0 0 5 5 4 1 AAA domain AAA_17 PF13207.1 GAP92935.1 - 7.3e-05 23.5 0.0 0.00043 21.0 0.0 2.4 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.17 GAP92935.1 - 9.1e-05 21.4 0.0 0.00026 19.9 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.24 GAP92935.1 - 0.0001 22.4 0.0 0.00048 20.3 0.0 2.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Abhydrolase_6 PF12697.2 GAP92935.1 - 0.00074 19.4 0.0 0.0026 17.6 0.0 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Viral_helicase1 PF01443.13 GAP92935.1 - 0.0039 16.7 0.0 0.0084 15.6 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DUF676 PF05057.9 GAP92935.1 - 0.0045 16.3 0.0 0.014 14.6 0.0 1.9 2 0 0 2 2 2 1 Putative serine esterase (DUF676) AAA_16 PF13191.1 GAP92935.1 - 0.0052 16.7 4.7 0.025 14.5 0.0 3.6 3 1 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 GAP92935.1 - 0.0054 16.6 0.0 0.016 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 GAP92935.1 - 0.007 15.8 0.1 0.78 9.1 0.0 3.4 3 1 0 3 3 3 1 AAA-like domain Cutinase PF01083.17 GAP92935.1 - 0.017 14.8 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Cutinase AAA_25 PF13481.1 GAP92935.1 - 0.017 14.4 0.0 0.063 12.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 GAP92935.1 - 0.02 14.3 0.0 0.1 12.0 0.0 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_19 PF13245.1 GAP92935.1 - 0.035 13.8 0.0 0.099 12.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 GAP92935.1 - 0.051 13.7 0.0 0.16 12.1 0.0 1.9 2 0 0 2 2 1 0 RNA helicase NTPase_1 PF03266.10 GAP92935.1 - 0.054 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 NTPase MobB PF03205.9 GAP92935.1 - 0.31 10.7 0.0 0.6 9.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF3433 PF11915.3 GAP92936.1 - 1.5e-27 95.5 9.8 2.8e-21 75.4 2.5 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) PSK_trans_fac PF07704.6 GAP92937.1 - 0.44 11.2 5.5 0.68 10.6 3.8 1.4 1 0 0 1 1 1 0 Rv0623-like transcription factor DUF4106 PF13388.1 GAP92937.1 - 1.9 7.3 6.6 2.3 7.1 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) BNR_2 PF13088.1 GAP92938.1 - 1.7e-08 34.1 0.0 4.7e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 BNR repeat-like domain PQQ_3 PF13570.1 GAP92938.1 - 0.041 14.1 1.4 1.8 8.9 0.3 3.3 3 0 0 3 3 3 0 PQQ-like domain fn3 PF00041.16 GAP92939.1 - 0.0016 18.5 3.8 0.004 17.2 1.8 2.4 2 0 0 2 2 2 1 Fibronectin type III domain Pyridoxal_deC PF00282.14 GAP92940.1 - 7.6e-62 208.8 0.0 1.2e-61 208.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 GAP92940.1 - 0.00027 19.7 0.0 0.00069 18.4 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V SSP160 PF06933.6 GAP92941.1 - 2.3 6.1 19.3 2.6 5.9 13.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Med3 PF11593.3 GAP92941.1 - 6.2 5.9 10.4 7.1 5.7 7.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal WD40 PF00400.27 GAP92944.1 - 6.1e-11 41.7 14.6 4e-06 26.4 0.1 5.0 4 0 0 4 4 4 2 WD domain, G-beta repeat RWD PF05773.17 GAP92944.1 - 0.0019 18.0 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 RWD domain UQ_con PF00179.21 GAP92945.1 - 3.5e-46 156.1 0.0 4.1e-46 155.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAP92945.1 - 0.00012 21.8 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 GAP92945.1 - 0.064 12.9 0.1 0.11 12.1 0.1 1.5 1 1 0 1 1 1 0 UEV domain ADH_zinc_N PF00107.21 GAP92946.1 - 1.7e-13 50.2 1.1 3.3e-13 49.2 0.8 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF4265 PF14085.1 GAP92946.1 - 0.00019 21.1 0.0 0.054 13.2 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4265) SET PF00856.23 GAP92947.1 - 3.5e-14 53.4 0.0 9.5e-14 52.0 0.0 1.7 1 1 0 1 1 1 1 SET domain CBP4 PF07960.6 GAP92948.1 - 1e-38 131.8 0.9 1.2e-38 131.6 0.6 1.0 1 0 0 1 1 1 1 CBP4 DUF2852 PF11014.3 GAP92948.1 - 0.017 15.0 0.4 0.032 14.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) ERCC4 PF02732.10 GAP92948.1 - 0.06 13.0 0.4 0.075 12.7 0.3 1.1 1 0 0 1 1 1 0 ERCC4 domain UPF0258 PF06789.7 GAP92948.1 - 0.09 12.8 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) Endonuc_Holl PF10107.4 GAP92948.1 - 0.21 11.2 2.0 0.27 10.8 1.4 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Seryl_tRNA_N PF02403.17 GAP92948.1 - 1.2 9.1 5.7 1.9 8.5 3.9 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Sel1 PF08238.7 GAP92949.1 - 8.2e-45 150.2 22.0 1.9e-06 28.3 0.0 7.9 7 0 0 7 7 7 7 Sel1 repeat Pkinase PF00069.20 GAP92950.1 - 4.8e-07 29.1 0.0 0.00026 20.2 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAP92950.1 - 6.1e-07 28.7 0.0 0.00015 20.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Glyco_hydro_97 PF10566.4 GAP92950.1 - 0.1 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycoside hydrolase 97 UB2H PF14814.1 GAP92950.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Bifunctional transglycosylase second domain AAA_13 PF13166.1 GAP92951.1 - 0.0054 15.2 2.4 0.0083 14.6 1.7 1.2 1 0 0 1 1 1 1 AAA domain Mitofilin PF09731.4 GAP92951.1 - 0.017 13.8 0.4 0.017 13.8 0.3 1.6 2 0 0 2 2 2 0 Mitochondrial inner membrane protein FliJ PF02050.11 GAP92951.1 - 0.42 10.6 3.6 1.5 8.9 0.5 2.7 2 1 0 2 2 2 0 Flagellar FliJ protein WD40 PF00400.27 GAP92952.1 - 2.1e-68 223.9 34.7 5.8e-12 45.0 0.2 11.9 12 0 0 12 12 12 9 WD domain, G-beta repeat Nup160 PF11715.3 GAP92952.1 - 0.00013 20.2 6.7 0.42 8.6 0.0 4.7 3 2 0 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAP92952.1 - 0.00024 20.0 0.9 0.58 8.8 0.1 4.5 1 1 3 6 6 6 1 Nup133 N terminal like PD40 PF07676.7 GAP92952.1 - 0.0033 17.0 7.7 2.8 7.7 0.0 6.1 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 GAP92952.1 - 0.0036 16.4 12.4 7.6 5.5 0.1 6.6 7 3 3 10 10 10 2 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 GAP92952.1 - 0.0061 15.8 4.4 3.2 7.1 0.0 4.6 4 0 0 4 4 4 1 Proteasome subunit A N-terminal signature HTH_29 PF13551.1 GAP92953.1 - 5e-09 36.2 0.6 7.8e-09 35.6 0.4 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 GAP92953.1 - 1.2e-05 25.9 5.0 1.7e-05 25.5 0.8 2.8 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.1 GAP92953.1 - 0.00026 20.5 2.0 0.0082 15.7 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_7 PF02796.10 GAP92953.1 - 0.0011 18.8 0.1 0.013 15.3 0.0 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_38 PF13936.1 GAP92953.1 - 0.0028 17.1 1.2 0.3 10.6 0.0 2.7 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.13 GAP92953.1 - 0.0045 17.0 0.6 0.011 15.7 0.2 1.9 2 0 0 2 2 2 1 Transposase HTH_24 PF13412.1 GAP92953.1 - 0.013 14.8 0.3 0.29 10.5 0.0 2.4 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_28 PF13518.1 GAP92953.1 - 0.037 14.0 1.9 0.15 12.1 0.1 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain MarR_2 PF12802.2 GAP92953.1 - 0.075 12.7 0.1 1 9.0 0.0 2.3 2 0 0 2 2 2 0 MarR family HET PF06985.6 GAP92954.1 - 8.5e-29 100.4 0.1 2.1e-28 99.2 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ArabFuran-catal PF09206.6 GAP92955.1 - 8e-144 478.5 18.1 1.2e-143 477.9 12.5 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.8 GAP92955.1 - 2e-50 170.2 0.7 3.2e-50 169.5 0.5 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) zf-3CxxC PF13695.1 GAP92956.1 - 1.6e-30 105.2 1.0 2.2e-30 104.7 0.7 1.2 1 0 0 1 1 1 1 Zinc-binding domain OSTMP1 PF09777.4 GAP92956.1 - 0.036 13.2 0.7 0.041 13.0 0.5 1.1 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor BNR_2 PF13088.1 GAP92957.1 - 9.8e-19 67.6 1.7 3.9e-11 42.7 0.7 3.0 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 GAP92957.1 - 1.2e-05 24.3 32.1 0.64 10.0 1.3 6.7 7 0 0 7 7 7 5 BNR/Asp-box repeat BNR_3 PF13859.1 GAP92957.1 - 0.00034 19.7 0.0 0.0024 16.9 0.0 2.0 1 1 0 2 2 2 1 BNR repeat-like domain PPDFL PF15060.1 GAP92957.1 - 0.00083 19.3 0.8 0.002 18.1 0.5 1.6 1 0 0 1 1 1 1 Differentiation and proliferation regulator Mo-co_dimer PF03404.11 GAP92957.1 - 0.0027 17.3 3.1 0.038 13.6 0.0 3.2 4 0 0 4 4 4 1 Mo-co oxidoreductase dimerisation domain Glyco_hydro_43 PF04616.9 GAP92957.1 - 0.1 11.6 1.0 4.4 6.3 0.0 2.5 1 1 1 2 2 2 0 Glycosyl hydrolases family 43 AA_permease_2 PF13520.1 GAP92958.1 - 6.2e-65 219.3 34.9 8.4e-65 218.9 24.2 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAP92958.1 - 2.4e-29 102.0 23.7 2.4e-29 102.0 16.4 2.1 2 1 0 2 2 2 1 Amino acid permease DUF4097 PF13349.1 GAP92958.1 - 0.11 12.0 0.2 0.4 10.2 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) ADH_zinc_N PF00107.21 GAP92959.1 - 3e-30 104.4 0.0 5.3e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP92959.1 - 2.7e-25 88.2 0.1 5.1e-25 87.3 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAP92959.1 - 0.00038 21.3 0.0 0.00077 20.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 GAP92959.1 - 0.013 15.1 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated TrkA_N PF02254.13 GAP92959.1 - 0.093 12.7 0.1 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain tRNA-synt_1 PF00133.17 GAP92960.1 - 3.5e-50 170.6 0.0 1.4e-29 102.5 0.0 6.0 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 GAP92960.1 - 3.4e-33 114.5 0.0 6.4e-33 113.6 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 GAP92960.1 - 1.1e-29 103.3 0.0 4.2e-23 81.6 0.0 4.3 3 1 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 GAP92960.1 - 2.9e-10 40.1 0.0 7.5e-10 38.7 0.0 1.7 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 GAP92960.1 - 0.04 12.7 0.0 0.069 11.9 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (R) KAT11 PF08214.6 GAP92962.1 - 2.4e-86 289.9 0.0 3.2e-86 289.5 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Ribonucleas_3_3 PF14622.1 GAP92963.1 - 8.1e-25 87.2 0.0 1.6e-24 86.3 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease-III-like DUF212 PF02681.9 GAP92963.1 - 0.14 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Divergent PAP2 family Peptidase_S8 PF00082.17 GAP92965.1 - 1.2e-20 73.8 0.0 1.8e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Med3 PF11593.3 GAP92965.1 - 0.034 13.3 2.5 0.071 12.3 1.8 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal HET PF06985.6 GAP92967.1 - 2.8e-30 105.2 2.8 2.8e-30 105.2 2.0 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF605 PF04652.11 GAP92967.1 - 0.11 11.8 12.8 0.19 11.0 8.9 1.3 1 0 0 1 1 1 0 Vta1 like Fib_alpha PF08702.5 GAP92967.1 - 3.6 7.6 9.2 9.2 6.3 6.4 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family dUTPase PF00692.14 GAP92968.1 - 1.3e-08 34.3 0.0 1.5e-08 34.1 0.0 1.0 1 0 0 1 1 1 1 dUTPase FoP_duplication PF13865.1 GAP92969.1 - 7 7.1 6.1 7.2 7.1 4.2 1.1 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 MFS_1 PF07690.11 GAP92970.1 - 6.5e-31 107.3 31.9 6.5e-31 107.3 22.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_S9 PF00326.16 GAP92971.1 - 3.9e-45 153.6 0.8 6.1e-45 153.0 0.6 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAP92971.1 - 8.7e-08 32.0 0.2 3.6e-07 30.0 0.1 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family PD40 PF07676.7 GAP92971.1 - 3.2e-05 23.4 2.5 0.011 15.3 0.0 3.9 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat MFS_1 PF07690.11 GAP92972.1 - 4.3e-43 147.3 25.1 4.3e-43 147.3 17.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP92972.1 - 9.3e-15 54.1 9.4 9.3e-15 54.1 6.5 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.15 GAP92972.1 - 0.0024 15.9 0.1 0.0024 15.9 0.1 2.4 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family DUF3852 PF12963.2 GAP92972.1 - 0.039 13.9 0.8 0.11 12.5 0.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3852) Patatin PF01734.17 GAP92973.1 - 7.8e-16 58.6 0.0 1.8e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase ABC_tran PF00005.22 GAP92973.1 - 0.0012 19.1 0.0 0.003 17.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter zf-C3HC4_2 PF13923.1 GAP92973.1 - 0.0021 18.0 11.6 0.0052 16.7 8.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF258 PF03193.11 GAP92973.1 - 0.012 14.8 0.0 0.026 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAP92973.1 - 0.022 14.8 0.0 0.059 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 GAP92973.1 - 0.026 14.4 0.1 0.46 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.18 GAP92973.1 - 0.06 13.3 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase zf-C3HC4_3 PF13920.1 GAP92973.1 - 0.14 11.8 8.3 0.29 10.8 5.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AAA_29 PF13555.1 GAP92973.1 - 0.14 11.6 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-RING_2 PF13639.1 GAP92973.1 - 0.56 10.0 10.1 1.3 8.8 7.0 1.6 1 0 0 1 1 1 0 Ring finger domain GSK-3_bind PF05350.7 GAP92973.1 - 1.7 8.0 4.8 3.1 7.1 0.0 2.6 3 0 0 3 3 3 0 Glycogen synthase kinase-3 binding Pyr_redox_3 PF13738.1 GAP92974.1 - 1.3e-20 74.3 0.0 2.8e-20 73.2 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAP92974.1 - 1.2e-09 36.9 0.0 1.9e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 GAP92974.1 - 9.6e-09 34.6 0.0 4.4e-08 32.4 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAP92974.1 - 5.8e-07 29.5 0.0 9.2e-07 28.9 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP92974.1 - 7.7e-06 25.8 0.1 2.9e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAP92974.1 - 0.00024 20.1 0.7 0.12 11.2 0.0 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 GAP92974.1 - 0.015 14.3 0.0 0.061 12.4 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 GAP92974.1 - 0.044 14.1 0.2 20 5.6 0.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 GAP92976.1 - 2.9e-35 121.6 23.8 2.9e-35 121.6 16.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP92976.1 - 4.1e-11 42.1 5.0 4.1e-11 42.1 3.5 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter PTR2 PF00854.16 GAP92976.1 - 0.0008 18.2 0.7 0.18 10.5 0.0 2.3 2 0 0 2 2 2 2 POT family adh_short PF00106.20 GAP92977.1 - 2.5e-12 47.0 0.0 3.6e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP92977.1 - 5e-08 32.8 0.0 1.8e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 KR domain GMC_oxred_N PF00732.14 GAP92978.1 - 6.1e-50 170.0 0.0 8.2e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAP92978.1 - 2.8e-37 128.1 0.0 4.5e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAP92978.1 - 8.9e-07 28.1 1.0 8.5e-05 21.6 0.7 2.5 2 2 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAP92978.1 - 8.1e-05 22.5 0.1 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAP92978.1 - 0.00061 18.7 0.6 0.0031 16.4 0.6 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 GAP92978.1 - 0.0013 18.7 0.9 0.0077 16.2 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAP92978.1 - 0.0016 17.4 0.1 0.0024 16.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 GAP92978.1 - 0.0041 17.2 0.3 1.9 8.5 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAP92978.1 - 0.43 11.0 1.9 3.4 8.1 0.4 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GFO_IDH_MocA PF01408.17 GAP92979.1 - 1.8e-17 63.9 0.1 4e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 GAP92979.1 - 9.4e-09 35.0 0.0 1.9e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 GAP92979.1 - 0.01 16.2 0.0 0.018 15.4 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 GAP92979.1 - 0.05 13.8 0.0 0.086 13.1 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_kinase PF01513.16 GAP92980.1 - 2.8e-45 154.2 0.0 1.8e-44 151.6 0.0 1.9 1 1 0 1 1 1 1 ATP-NAD kinase ERM PF00769.14 GAP92981.1 - 0.036 13.6 0.0 0.042 13.3 0.0 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family MT0933_antitox PF14013.1 GAP92981.1 - 0.44 10.6 4.3 0.92 9.6 2.8 1.8 1 1 0 1 1 1 0 MT0933-like antitoxin protein Serglycin PF04360.7 GAP92982.1 - 0.057 13.1 0.6 0.089 12.5 0.4 1.3 1 0 0 1 1 1 0 Serglycin MRJP PF03022.11 GAP92983.1 - 1.9e-35 122.5 0.0 2.7e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 Major royal jelly protein SGL PF08450.7 GAP92983.1 - 0.0018 17.7 0.0 0.017 14.4 0.0 2.5 2 1 1 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 GAP92983.1 - 0.0036 17.2 3.0 9.5 6.3 0.0 4.3 4 0 0 4 4 4 1 NHL repeat PD40 PF07676.7 GAP92983.1 - 0.023 14.3 0.4 2.5 7.8 0.1 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Abhydrolase_2 PF02230.11 GAP92984.1 - 9.9e-27 93.7 0.0 8.6e-26 90.7 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 GAP92984.1 - 5.9e-11 42.6 5.9 8.7e-05 22.5 2.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP92984.1 - 3.9e-08 33.1 0.0 5.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAP92984.1 - 2.8e-05 23.4 0.1 0.00011 21.5 0.0 2.0 3 0 0 3 3 3 1 Prolyl oligopeptidase family LIP PF03583.9 GAP92984.1 - 0.00014 21.1 0.0 0.00022 20.5 0.0 1.3 1 0 0 1 1 1 1 Secretory lipase FSH1 PF03959.8 GAP92984.1 - 0.0055 16.1 0.0 0.01 15.2 0.0 1.5 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 GAP92984.1 - 0.015 14.8 0.1 7.3 6.1 0.1 2.6 2 1 0 3 3 3 0 alpha/beta hydrolase fold Peptidase_M24 PF00557.19 GAP92985.1 - 9.8e-43 146.1 0.0 1.2e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 GAP92985.1 - 0.0016 18.2 8.5 0.0016 18.2 5.9 2.0 2 0 0 2 2 2 1 MYND finger Acyl_transf_1 PF00698.16 GAP92987.1 - 2e-55 188.3 0.0 6.5e-52 176.8 0.0 3.7 3 1 0 3 3 3 2 Acyl transferase domain MaoC_dehydratas PF01575.14 GAP92987.1 - 5.5e-27 93.5 0.0 1.2e-26 92.4 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 GAP92987.1 - 6.2e-26 89.9 0.9 2.7e-25 87.9 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 GAP92987.1 - 6.6e-06 25.9 0.0 1.6e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase MmgE_PrpD PF03972.9 GAP92988.1 - 7e-109 363.9 0.0 8.7e-109 363.6 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DUF3832 PF12909.2 GAP92988.1 - 0.23 11.5 1.7 0.76 9.8 0.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3832) MmgE_PrpD PF03972.9 GAP92989.1 - 1.7e-57 194.6 0.0 1.9e-57 194.4 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Fungal_trans PF04082.13 GAP92990.1 - 8.5e-14 51.0 2.2 1.8e-13 49.9 1.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP92990.1 - 7.8e-10 38.5 12.8 1.6e-09 37.4 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.21 GAP92991.1 - 1.5e-23 83.5 0.3 3.3e-23 82.4 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 GAP92991.1 - 9.3e-17 60.9 0.0 1.9e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short_C2 PF13561.1 GAP92991.1 - 1.3e-14 54.5 0.0 2.6e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAP92991.1 - 1.9e-05 24.6 0.9 3e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAP92991.1 - 0.071 12.7 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 KR domain Citrate_synt PF00285.16 GAP92992.1 - 3.7e-102 341.6 0.0 4.5e-102 341.4 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase HET PF06985.6 GAP92993.1 - 2.6e-07 30.8 0.0 5.3e-05 23.4 0.0 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DnaJ PF00226.26 GAP92994.1 - 1.3e-18 66.4 0.0 2e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF1311 PF07007.7 GAP92994.1 - 0.011 15.7 0.1 0.022 14.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1311) Tannase PF07519.6 GAP92995.1 - 1e-99 334.4 0.1 6.1e-99 331.8 0.0 1.8 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 GAP92995.1 - 0.0034 17.2 0.0 0.0066 16.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAP92995.1 - 0.037 13.2 0.0 1 8.5 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Glyco_hydro_43 PF04616.9 GAP92996.1 - 1.3e-46 159.0 2.5 1.5e-46 158.8 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Cas_Cas2CT1978 PF09707.5 GAP92996.1 - 0.029 14.2 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas2CT1978) Methyltransf_31 PF13847.1 GAP92997.1 - 1.6e-09 37.5 0.0 2e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP92997.1 - 7.5e-09 36.1 0.1 1.1e-08 35.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAP92997.1 - 3.7e-07 29.6 0.1 4.5e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 GAP92997.1 - 5.6e-07 29.8 0.0 7.4e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP92997.1 - 1.4e-06 28.6 0.0 1.9e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP92997.1 - 4.3e-06 26.5 0.0 5.5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP92997.1 - 4.7e-06 26.6 0.1 6.5e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP92997.1 - 1.1e-05 25.8 0.0 1.9e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 GAP92997.1 - 0.00035 19.8 0.1 0.0004 19.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.9 GAP92997.1 - 0.00046 19.4 0.0 0.00057 19.1 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.13 GAP92997.1 - 0.00049 19.2 0.0 0.00057 19.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 GAP92997.1 - 0.00087 18.8 0.0 0.00093 18.7 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 GAP92997.1 - 0.0011 18.6 0.0 0.0014 18.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 GAP92997.1 - 0.0083 15.2 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase UPF0020 PF01170.13 GAP92997.1 - 0.024 14.2 0.0 0.031 13.8 0.0 1.1 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DREV PF05219.7 GAP92997.1 - 0.024 13.5 0.0 0.027 13.3 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase RrnaAD PF00398.15 GAP92997.1 - 0.053 12.5 0.0 0.062 12.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase 3HCDH_N PF02737.13 GAP92997.1 - 0.059 13.0 0.1 0.071 12.7 0.1 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TPR_2 PF07719.12 GAP92998.1 - 6.6e-11 41.2 2.7 0.00068 19.3 0.1 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAP92998.1 - 2.3e-09 36.4 1.2 0.047 13.3 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAP92998.1 - 1.3e-08 34.3 4.4 0.00014 21.4 0.1 3.7 2 1 1 3 3 3 3 TPR repeat TPR_12 PF13424.1 GAP92998.1 - 5.8e-08 32.5 14.4 0.00015 21.6 1.5 4.1 1 1 2 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 GAP92998.1 - 1.2e-05 24.7 1.7 0.17 11.7 0.3 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat HET PF06985.6 GAP92998.1 - 2.4e-05 24.4 0.1 8.1e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_14 PF13428.1 GAP92998.1 - 2.8e-05 24.3 3.1 8.4 7.3 0.0 6.1 4 1 2 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAP92998.1 - 3.3e-05 24.4 4.9 6 7.6 0.1 4.8 2 1 2 4 4 4 1 Tetratricopeptide repeat Ank_4 PF13637.1 GAP92998.1 - 5.8e-05 23.4 0.0 0.00017 21.9 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAP92998.1 - 0.00093 19.4 0.0 0.0027 17.9 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAP92998.1 - 0.0039 17.3 0.2 0.056 13.7 0.0 3.0 5 0 0 5 5 3 1 Ankyrin repeats (many copies) TIR PF01582.15 GAP92998.1 - 0.024 14.0 0.3 0.069 12.5 0.0 1.9 2 0 0 2 2 2 0 TIR domain Ank PF00023.25 GAP92998.1 - 0.035 13.9 0.0 3.5 7.6 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat TPR_6 PF13174.1 GAP92998.1 - 0.055 13.9 0.2 10 6.8 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Mod_r PF07200.8 GAP92998.1 - 0.061 13.2 0.7 0.16 11.8 0.4 1.7 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein TPR_19 PF14559.1 GAP92998.1 - 0.16 12.3 1.6 1.3 9.4 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat FliT PF05400.8 GAP92998.1 - 0.43 11.0 6.9 21 5.6 3.0 2.9 2 1 1 3 3 3 0 Flagellar protein FliT Acyl-CoA_dh_1 PF00441.19 GAP92999.1 - 3.8e-18 66.0 4.5 6.8e-18 65.1 3.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 GAP92999.1 - 1.3e-11 43.8 0.3 3e-11 42.6 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 GAP92999.1 - 0.00012 22.3 6.1 0.00024 21.3 4.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAP92999.1 - 0.0053 17.3 0.1 0.013 16.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain AMP-binding PF00501.23 GAP93000.1 - 6.6e-92 308.0 0.0 1.5e-91 306.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 GAP93000.1 - 1.1e-87 293.7 0.0 2e-87 292.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAP93000.1 - 2.3e-63 214.4 0.1 3.5e-63 213.8 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 GAP93000.1 - 7.9e-59 198.3 0.9 1.2e-56 191.3 0.5 2.9 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 GAP93000.1 - 1.2e-52 178.2 1.4 4.7e-50 169.7 0.9 3.1 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 GAP93000.1 - 1.9e-47 161.2 0.0 2.5e-46 157.6 0.0 2.4 2 0 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.17 GAP93000.1 - 2.2e-43 146.8 1.0 4.6e-43 145.8 0.7 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 GAP93000.1 - 3e-21 75.4 0.0 1.9e-10 40.8 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.16 GAP93000.1 - 7.2e-13 48.5 0.0 6.1e-08 32.3 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 GAP93000.1 - 4.3e-12 46.7 0.4 2.4e-11 44.4 0.0 2.6 3 0 0 3 3 1 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.10 GAP93000.1 - 1.3e-06 27.5 0.0 0.0085 15.0 0.0 2.3 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 GAP93000.1 - 2.6e-05 24.2 0.2 0.36 10.8 0.0 3.4 3 0 0 3 3 3 2 NADH(P)-binding Thiolase_N PF00108.18 GAP93000.1 - 6.9e-05 21.9 0.1 0.00014 20.9 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.14 GAP93000.1 - 6.9e-05 21.6 0.0 0.26 9.9 0.0 2.5 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 GAP93000.1 - 0.0036 16.5 1.3 0.16 11.2 0.0 3.2 4 0 0 4 4 4 1 NmrA-like family Ribosomal_L30 PF00327.15 GAP93000.1 - 0.19 11.3 0.0 0.44 10.1 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e RmlD_sub_bind PF04321.12 GAP93000.1 - 0.27 10.1 0.0 22 3.7 0.0 2.8 2 1 0 2 2 2 0 RmlD substrate binding domain PhyH PF05721.8 GAP93001.1 - 4e-16 59.7 0.0 6.2e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) NAD_binding_10 PF13460.1 GAP93002.1 - 2.1e-07 31.1 0.0 3e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAP93002.1 - 1.6e-06 27.5 0.0 2.9e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 GAP93002.1 - 0.012 15.1 0.0 0.05 13.0 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 GAP93002.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain P5CR_dimer PF14748.1 GAP93003.1 - 2.3e-26 91.8 1.2 3.9e-26 91.1 0.8 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 GAP93003.1 - 1.2e-12 48.0 0.2 1.4e-11 44.6 0.0 2.5 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.12 GAP93003.1 - 0.0016 17.3 1.0 0.21 10.4 0.0 2.2 1 1 1 2 2 2 2 Prephenate dehydrogenase NAD_Gly3P_dh_N PF01210.18 GAP93003.1 - 0.0024 17.6 0.2 0.011 15.4 0.2 2.1 1 1 1 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DEC-1_N PF04625.8 GAP93004.1 - 0.55 8.8 4.2 0.76 8.3 2.9 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region CorA PF01544.13 GAP93005.1 - 0.015 14.3 0.4 0.039 12.9 0.4 1.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein P120R PF08062.6 GAP93006.1 - 0.22 11.8 2.9 0.38 11.1 2.0 1.3 1 0 0 1 1 1 0 P120R (NUC006) repeat HET PF06985.6 GAP93007.1 - 1.5e-22 80.2 1.7 4.7e-22 78.6 0.0 2.6 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) DUF3403 PF11883.3 GAP93007.1 - 0.27 11.5 1.0 0.6 10.4 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3403) Ribosomal_60s PF00428.14 GAP93007.1 - 5.6 7.4 17.5 0.33 11.3 7.4 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Pal1 PF08316.6 GAP93009.1 - 3.1e-47 160.5 1.4 1e-46 158.8 1.0 2.0 1 0 0 1 1 1 1 Pal1 cell morphology protein PAT1 PF09770.4 GAP93010.1 - 6.2 4.9 14.3 8.7 4.4 9.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Fasciclin PF02469.17 GAP93011.1 - 7.8e-39 132.6 0.0 3.9e-21 75.3 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain DUF2171 PF09939.4 GAP93012.1 - 0.082 12.9 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2171) Abhydrolase_1 PF00561.15 GAP93013.1 - 5.1e-19 68.7 0.0 1.3e-17 64.1 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAP93013.1 - 7.7e-12 45.5 1.7 1.3e-10 41.5 1.2 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 GAP93013.1 - 0.0052 16.2 0.0 0.0087 15.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase SAD_SRA PF02182.12 GAP93014.1 - 1.7e-28 98.8 0.0 2.3e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 SAD/SRA domain RR_TM4-6 PF06459.7 GAP93014.1 - 1.4 8.7 5.4 2.1 8.1 3.1 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 NAD_binding_2 PF03446.10 GAP93015.1 - 4e-30 104.8 0.4 6.7e-30 104.0 0.3 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 GAP93015.1 - 2.7e-09 37.1 0.0 5.3e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 GAP93015.1 - 1.3e-06 28.7 0.3 4.2e-06 27.0 0.2 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 GAP93015.1 - 0.00029 20.0 0.0 0.0006 19.0 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 GAP93015.1 - 0.0007 19.7 0.1 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Rossmann-like PF10727.4 GAP93015.1 - 0.0015 18.2 2.5 0.0015 18.2 1.7 2.4 2 1 1 3 3 3 1 Rossmann-like domain DUF4154 PF13689.1 GAP93015.1 - 0.08 12.5 0.0 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4154) DFP PF04127.10 GAP93016.1 - 3.8e-14 52.7 0.0 1.5e-05 24.6 0.0 3.2 2 1 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein MFS_1 PF07690.11 GAP93017.1 - 3.1e-41 141.2 67.0 2e-36 125.4 31.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAP93017.1 - 1.5e-05 23.6 25.0 1.5e-05 23.6 17.3 1.7 1 1 0 1 1 1 1 MFS/sugar transport protein Sugar_tr PF00083.19 GAP93017.1 - 0.00017 20.3 37.8 0.0031 16.1 12.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Wbp11 PF09429.5 GAP93018.1 - 1.3e-21 76.3 6.1 1.3e-21 76.3 4.2 2.0 2 0 0 2 2 2 1 WW domain binding protein 11 Pkinase PF00069.20 GAP93019.1 - 4.1e-58 196.5 0.2 3.2e-38 131.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAP93019.1 - 4.4e-28 98.0 0.6 6.7e-20 71.2 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 GAP93019.1 - 6.6e-07 29.7 0.2 2e-06 28.2 0.1 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 GAP93019.1 - 0.00052 19.0 0.0 0.0026 16.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 GAP93019.1 - 0.0033 17.2 1.4 0.12 12.0 0.0 3.3 2 2 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 GAP93019.1 - 0.15 10.9 0.0 0.26 10.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 CFEM PF05730.6 GAP93020.1 - 0.0027 17.4 2.3 0.0057 16.4 1.6 1.5 1 0 0 1 1 1 1 CFEM domain Ycf9 PF01737.12 GAP93020.1 - 0.72 9.3 4.6 8.6 5.8 0.1 3.3 3 0 0 3 3 3 0 YCF9 WSC PF01822.14 GAP93021.1 - 3.2e-10 39.7 8.7 6.6e-10 38.7 6.0 1.6 1 0 0 1 1 1 1 WSC domain Adeno_E3_CR2 PF02439.10 GAP93021.1 - 0.0025 17.3 0.0 0.0049 16.3 0.0 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Herpes_gE PF02480.11 GAP93021.1 - 0.037 12.2 2.0 0.038 12.2 0.2 1.7 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 GAP93021.1 - 0.067 13.5 0.0 0.31 11.4 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain AF1Q PF15017.1 GAP93021.1 - 0.12 12.2 0.1 0.3 11.0 0.1 1.6 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator IncA PF04156.9 GAP93021.1 - 0.21 11.1 0.0 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 IncA protein Tweety PF04906.8 GAP93021.1 - 0.38 9.1 0.4 0.58 8.5 0.3 1.1 1 0 0 1 1 1 0 Tweety GATA PF00320.22 GAP93022.1 - 1.4e-15 56.3 3.7 3e-15 55.2 2.6 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 GAP93022.1 - 5.3e-11 41.8 0.6 9.3e-11 41.1 0.4 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Pyrid_oxidase_2 PF13883.1 GAP93023.1 - 5.1e-33 114.2 0.0 3.4e-19 69.2 0.0 2.4 2 1 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_2 PF00890.19 GAP93023.1 - 0.091 11.5 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain Acatn PF13000.2 GAP93024.1 - 3.6e-151 504.3 23.9 5e-79 266.2 5.1 3.7 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 DUF3951 PF13131.1 GAP93024.1 - 0.053 13.3 1.0 0.22 11.2 0.7 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) CENP-O PF09496.5 GAP93025.1 - 1.1e-23 83.2 0.0 2.2e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component HALZ PF02183.13 GAP93025.1 - 0.065 12.9 0.3 0.065 12.9 0.2 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper Abhydrolase_6 PF12697.2 GAP93026.1 - 2.8e-20 73.1 2.9 3.5e-20 72.8 2.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP93026.1 - 2.4e-09 37.1 0.2 3.6e-09 36.5 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP93026.1 - 0.13 11.7 0.3 1.2 8.5 0.1 2.4 2 2 0 2 2 2 0 alpha/beta hydrolase fold p450 PF00067.17 GAP93028.1 - 7.4e-25 87.3 0.0 8.1e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 GAP93030.1 - 3.4e-12 45.6 0.0 2.5e-11 42.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_18 PF00704.23 GAP93031.1 - 6e-65 219.9 4.3 9.6e-65 219.2 3.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DNase_NucA_NucB PF14040.1 GAP93031.1 - 0.0016 18.5 0.3 0.005 16.9 0.2 1.8 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB LysM PF01476.15 GAP93032.1 - 1.3e-10 40.9 0.2 0.00041 20.1 0.0 3.5 3 0 0 3 3 3 2 LysM domain LysM PF01476.15 GAP93034.1 - 1.6e-24 85.4 0.1 2e-05 24.3 0.0 4.2 4 0 0 4 4 4 4 LysM domain HAP2-GCS1 PF10699.4 GAP93034.1 - 0.054 13.4 2.5 1.2 9.1 0.1 3.4 3 0 0 3 3 3 0 Male gamete fusion factor Rubella_E2 PF05749.6 GAP93034.1 - 0.095 11.9 25.4 0.021 14.0 4.1 2.8 1 1 2 3 3 3 0 Rubella membrane glycoprotein E2 Como_LCP PF02247.11 GAP93034.1 - 0.13 10.6 5.6 1.7 6.9 0.1 3.0 3 0 0 3 3 3 0 Large coat protein Sporozoite_P67 PF05642.6 GAP93034.1 - 4 5.1 15.8 0.72 7.6 4.5 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Mucin PF01456.12 GAP93034.1 - 4.6 7.0 39.8 0.31 10.8 4.1 3.0 3 0 0 3 3 3 0 Mucin-like glycoprotein Sugar_tr PF00083.19 GAP93035.1 - 2.7e-101 339.3 23.0 3.2e-101 339.1 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP93035.1 - 2.6e-20 72.4 41.2 3.6e-15 55.5 6.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily IlvC PF01450.14 GAP93035.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Ribonuclease PF00545.15 GAP93037.1 - 1e-18 67.1 0.0 1.7e-18 66.4 0.0 1.3 1 1 0 1 1 1 1 ribonuclease WD40 PF00400.27 GAP93038.1 - 5e-57 187.8 27.3 9.9e-13 47.4 0.4 12.8 12 1 0 12 12 12 8 WD domain, G-beta repeat NACHT PF05729.7 GAP93038.1 - 2.8e-09 36.8 0.0 9.9e-08 31.8 0.0 3.1 4 0 0 4 4 4 1 NACHT domain Nucleoporin_N PF08801.6 GAP93038.1 - 0.00095 18.0 0.5 0.14 10.8 0.0 3.7 3 2 1 4 4 4 1 Nup133 N terminal like PQQ_3 PF13570.1 GAP93038.1 - 0.041 14.1 0.8 14 6.1 0.0 4.4 4 0 0 4 4 4 0 PQQ-like domain RNase_H2_suC PF08615.6 GAP93039.1 - 0.078 12.8 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Daxx PF03344.10 GAP93039.1 - 1.3 7.3 10.1 1.9 6.9 7.0 1.1 1 0 0 1 1 1 0 Daxx Family TRAP_alpha PF03896.11 GAP93039.1 - 3.9 6.4 10.6 6.1 5.7 7.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit adh_short PF00106.20 GAP93040.1 - 2.6e-16 59.9 14.2 2.2e-15 57.0 9.8 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP93040.1 - 2.5e-14 53.6 0.0 3.5e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 GAP93040.1 - 0.00046 19.8 2.4 0.00083 19.0 1.7 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HCR PF07111.7 GAP93040.1 - 0.031 12.3 0.1 0.038 11.9 0.0 1.1 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) Mucin PF01456.12 GAP93040.1 - 0.041 13.6 0.5 0.083 12.6 0.3 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein KR PF08659.5 GAP93040.1 - 0.046 13.3 5.1 0.032 13.8 1.2 2.1 2 0 0 2 2 2 0 KR domain PLU-1 PF08429.6 GAP93041.1 - 4.8e-99 331.4 7.3 1.1e-96 323.6 5.3 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 GAP93041.1 - 4e-42 143.0 0.4 1e-41 141.7 0.3 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 GAP93041.1 - 6.4e-27 93.2 0.0 1.9e-26 91.7 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.24 GAP93041.1 - 2e-17 62.5 35.5 1.6e-10 40.5 3.2 4.2 4 0 0 4 4 4 2 PHD-finger JmjN PF02375.12 GAP93041.1 - 8.3e-15 54.0 0.2 2e-14 52.8 0.1 1.7 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 GAP93041.1 - 6.7e-13 48.4 6.1 1.7e-12 47.2 4.3 1.7 1 0 0 1 1 1 1 C5HC2 zinc finger zf-PHD-like PF15446.1 GAP93041.1 - 0.091 12.0 10.0 0.14 11.4 1.0 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 GAP93041.1 - 0.1 11.9 11.2 0.012 14.9 0.8 3.0 2 0 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.1 GAP93041.1 - 0.1 12.4 19.7 1.1 9.1 4.0 2.9 2 0 0 2 2 2 0 Ring finger domain GIY-YIG PF01541.19 GAP93042.1 - 9.6e-09 35.4 0.0 1.6e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.3 GAP93042.1 - 0.0036 17.2 0.6 0.006 16.5 0.4 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.1 GAP93042.1 - 0.0094 15.9 0.1 0.016 15.1 0.1 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain Prok-RING_1 PF14446.1 GAP93042.1 - 0.0098 15.6 3.8 0.023 14.4 0.3 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_2 PF13639.1 GAP93042.1 - 0.014 15.1 2.7 0.03 14.1 1.9 1.6 1 0 0 1 1 1 0 Ring finger domain zf-HC5HC2H PF13771.1 GAP93042.1 - 0.017 15.2 0.4 0.034 14.2 0.3 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain T5orf172 PF10544.4 GAP93042.1 - 0.037 14.4 0.0 0.074 13.4 0.0 1.5 1 0 0 1 1 1 0 T5orf172 domain PHD PF00628.24 GAP93042.1 - 0.2 11.3 2.3 0.4 10.4 1.6 1.5 1 0 0 1 1 1 0 PHD-finger DUF3449 PF11931.3 GAP93043.1 - 1.3e-74 249.9 1.6 7e-74 247.5 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) zf-met PF12874.2 GAP93043.1 - 2.3e-11 43.4 2.6 1.6e-09 37.6 0.3 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type SF3a60_bindingd PF12108.3 GAP93043.1 - 4e-09 35.8 0.0 9.5e-09 34.6 0.0 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.3 GAP93043.1 - 4.6e-09 36.1 5.3 7.4e-09 35.5 0.1 2.6 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 GAP93043.1 - 0.0018 18.3 3.8 0.012 15.7 0.5 2.8 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF951 PF06107.6 GAP93043.1 - 0.034 13.6 0.0 0.08 12.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) zf-C2H2_4 PF13894.1 GAP93043.1 - 0.044 14.1 3.7 0.91 10.0 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-U1 PF06220.7 GAP93043.1 - 0.078 12.5 0.4 0.2 11.2 0.2 1.6 1 0 0 1 1 1 0 U1 zinc finger zf-DBF PF07535.7 GAP93043.1 - 0.082 12.5 0.2 0.082 12.5 0.2 2.4 2 1 0 2 2 2 0 DBF zinc finger DUF2201_N PF13203.1 GAP93043.1 - 0.17 11.0 5.6 0.3 10.2 3.9 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Myb_CC_LHEQLE PF14379.1 GAP93043.1 - 0.19 11.3 4.6 1.3 8.6 3.2 2.4 1 1 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif zf-C2H2 PF00096.21 GAP93043.1 - 1.8 9.0 3.5 17 5.9 0.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type DEAD PF00270.24 GAP93044.1 - 5.4e-41 139.9 0.5 1.3e-40 138.6 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAP93044.1 - 3.8e-29 100.3 0.2 9.1e-29 99.1 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.1 GAP93044.1 - 0.011 15.3 0.5 0.027 14.0 0.3 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 GAP93044.1 - 0.02 14.6 0.2 0.049 13.4 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain Flavi_DEAD PF07652.9 GAP93044.1 - 0.026 14.2 0.5 0.12 12.1 0.1 2.3 1 1 0 1 1 1 0 Flavivirus DEAD domain ResIII PF04851.10 GAP93044.1 - 0.031 14.0 0.1 0.075 12.8 0.1 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 GAP93044.1 - 0.087 12.4 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.1 GAP93044.1 - 0.21 11.7 0.8 0.92 9.6 0.6 2.0 1 1 0 1 1 1 0 AAA domain Cutinase PF01083.17 GAP93045.1 - 1e-50 171.9 9.2 1e-50 171.9 6.4 1.4 2 0 0 2 2 2 1 Cutinase CBM_1 PF00734.13 GAP93045.1 - 2.2e-11 43.2 19.2 2.2e-11 43.2 13.3 4.0 4 1 0 4 4 4 1 Fungal cellulose binding domain PE-PPE PF08237.6 GAP93045.1 - 5.2e-05 22.7 0.1 7.1e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.2 GAP93045.1 - 0.037 13.8 0.4 0.24 11.2 0.3 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP93045.1 - 0.092 12.2 0.1 0.29 10.6 0.0 1.7 2 1 0 2 2 2 0 alpha/beta hydrolase fold Glyco_hydro_11 PF00457.12 GAP93046.1 - 4.2e-76 254.3 18.5 5.8e-76 253.9 12.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CBM_1 PF00734.13 GAP93046.1 - 1.3e-11 43.9 19.2 4e-11 42.3 13.3 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain RHIM PF12721.2 GAP93046.1 - 0.42 11.0 8.5 0.44 10.9 0.2 3.7 3 1 0 3 3 3 0 RIP homotypic interaction motif Tannase PF07519.6 GAP93047.1 - 3.9e-98 329.2 2.8 9e-96 321.4 2.0 2.4 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 GAP93047.1 - 1.1e-05 25.2 0.3 0.049 13.3 0.1 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP93047.1 - 0.0004 20.0 0.1 0.00058 19.4 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAP93047.1 - 0.00042 20.2 9.8 0.00042 20.2 6.8 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAP93047.1 - 0.00092 18.4 0.4 0.5 9.5 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Glyco_hydro_61 PF03443.9 GAP93048.1 - 1.2e-79 267.2 0.0 1.2e-79 267.2 0.0 2.2 2 1 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 GAP93048.1 - 1.9e-10 40.1 10.1 5.6e-10 38.7 7.0 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Serglycin PF04360.7 GAP93048.1 - 0.041 13.6 1.2 0.076 12.7 0.9 1.5 1 0 0 1 1 1 0 Serglycin Mito_carr PF00153.22 GAP93049.1 - 2.2e-16 59.3 0.4 0.00025 20.7 0.1 5.4 4 1 0 4 4 4 4 Mitochondrial carrier protein AP_endonuc_2 PF01261.19 GAP93050.1 - 1.1e-09 37.8 0.0 2.1e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel ADH_N PF08240.7 GAP93051.1 - 2.1e-28 98.2 0.1 4.7e-28 97.1 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAP93051.1 - 1.3e-09 37.6 0.3 2.8e-09 36.5 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 GAP93051.1 - 1.4e-06 27.8 0.5 2.9e-06 26.8 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated HI0933_like PF03486.9 GAP93051.1 - 0.0019 16.7 0.1 0.0027 16.2 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 GAP93051.1 - 0.042 12.8 0.1 0.062 12.3 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 GAP93051.1 - 0.052 12.4 0.6 0.076 11.8 0.2 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAP93051.1 - 0.079 11.7 0.8 0.13 11.1 0.4 1.4 1 1 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 GAP93051.1 - 0.083 12.9 0.2 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 GAP93051.1 - 0.088 12.3 0.2 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 GAP93051.1 - 0.099 12.7 0.0 0.31 11.1 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Methyltransf_18 PF12847.2 GAP93051.1 - 0.099 13.2 0.0 0.44 11.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Abhydrolase_6 PF12697.2 GAP93052.1 - 2.2e-17 63.7 0.2 2.7e-17 63.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP93052.1 - 3e-07 30.3 0.0 3.7e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAP93052.1 - 0.0016 18.0 0.1 0.0034 16.9 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein DUF900 PF05990.7 GAP93052.1 - 0.014 14.7 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Thioesterase PF00975.15 GAP93052.1 - 0.052 13.7 0.0 2.2 8.4 0.0 2.4 2 1 0 2 2 2 0 Thioesterase domain Abhydrolase_8 PF06259.7 GAP93052.1 - 0.057 12.9 0.0 0.089 12.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_1 PF00561.15 GAP93052.1 - 0.1 12.1 0.0 4 6.9 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF676 PF05057.9 GAP93052.1 - 0.12 11.6 0.1 0.34 10.1 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Ank_2 PF12796.2 GAP93053.1 - 2.4e-35 120.7 0.0 1.5e-18 66.9 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Pkinase PF00069.20 GAP93053.1 - 1.5e-26 93.1 0.0 3e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ank PF00023.25 GAP93053.1 - 1.5e-18 65.5 0.0 1.4e-06 27.8 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Pkinase_Tyr PF07714.12 GAP93053.1 - 5.8e-16 58.3 0.0 1.9e-15 56.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Ank_5 PF13857.1 GAP93053.1 - 2.5e-14 52.9 0.1 9.7e-08 32.0 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAP93053.1 - 6.4e-13 48.8 0.0 3.9e-08 33.5 0.0 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP93053.1 - 2.6e-10 39.5 0.0 0.012 15.7 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat Patatin PF01734.17 GAP93053.1 - 0.00024 21.1 0.1 0.0036 17.2 0.0 2.7 3 0 0 3 3 3 1 Patatin-like phospholipase Lipoxygenase PF00305.14 GAP93054.1 - 6.6e-31 107.0 0.0 8.5e-31 106.6 0.0 1.1 1 0 0 1 1 1 1 Lipoxygenase Peroxidase_2 PF01328.12 GAP93055.1 - 3.5e-13 48.9 0.0 1.3e-12 47.0 0.0 1.7 1 1 0 1 1 1 1 Peroxidase, family 2 4HBT_2 PF13279.1 GAP93056.1 - 3.6e-08 33.8 0.0 4.5e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily MFS_1 PF07690.11 GAP93057.1 - 3.1e-28 98.5 39.0 3.1e-28 98.5 27.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily EmrE PF13536.1 GAP93057.1 - 7.8 6.7 48.7 2.1 8.5 5.9 4.5 2 2 2 4 4 4 0 Multidrug resistance efflux transporter HlyIII PF03006.15 GAP93058.1 - 1.1e-46 159.0 16.5 1.2e-46 158.8 11.5 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF4383 PF14325.1 GAP93058.1 - 0.16 12.0 5.8 4.6 7.2 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4383) p450 PF00067.17 GAP93059.1 - 2.8e-62 210.7 0.0 3.8e-62 210.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ComX PF05952.7 GAP93059.1 - 0.05 13.1 0.0 0.27 10.7 0.0 2.0 2 0 0 2 2 2 0 Bacillus competence pheromone ComX PNP_UDP_1 PF01048.15 GAP93060.1 - 7.5e-14 51.2 0.4 7.5e-13 48.0 0.2 2.2 1 1 0 1 1 1 1 Phosphorylase superfamily WD40 PF00400.27 GAP93061.1 - 4.2e-23 80.3 10.4 1.6e-11 43.6 0.2 5.9 7 0 0 7 7 7 2 WD domain, G-beta repeat NACHT PF05729.7 GAP93061.1 - 2.1e-19 69.8 0.0 3.5e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 GAP93061.1 - 1.3e-05 25.3 0.0 5.3e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain PD40 PF07676.7 GAP93061.1 - 0.00019 20.9 0.0 1.7 8.4 0.0 4.4 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 GAP93061.1 - 0.0054 15.5 0.6 0.45 9.2 0.1 3.0 2 1 0 2 2 2 1 Nup133 N terminal like AAA_22 PF13401.1 GAP93061.1 - 0.0086 16.2 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 GAP93061.1 - 0.024 14.7 0.0 0.057 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Nup160 PF11715.3 GAP93061.1 - 0.029 12.5 4.7 3.6 5.6 0.0 4.3 4 1 2 6 6 6 0 Nucleoporin Nup120/160 AAA_25 PF13481.1 GAP93061.1 - 0.041 13.2 0.0 0.18 11.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 GAP93061.1 - 0.045 13.4 0.0 0.28 10.8 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase AAA_19 PF13245.1 GAP93061.1 - 0.046 13.4 0.0 0.43 10.3 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain Proteasome_A_N PF10584.4 GAP93061.1 - 0.2 11.0 4.7 1.3 8.4 0.1 3.8 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature tRNA-synt_2b PF00587.20 GAP93062.1 - 4.9e-65 218.3 0.0 7.4e-65 217.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAP93062.1 - 3.2e-20 71.8 0.1 1.1e-19 70.0 0.0 2.1 3 0 0 3 3 3 1 Anticodon binding domain Glyco_hyd_65N_2 PF14498.1 GAP93063.1 - 5.2e-54 183.4 0.1 7.7e-54 182.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain DUF4066 PF13278.1 GAP93063.1 - 7.1e-25 87.2 0.0 1.3e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 GAP93063.1 - 5.6e-10 38.8 0.0 1.2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family PHO4 PF01384.15 GAP93064.1 - 1.9e-113 378.3 16.1 2.4e-113 378.0 11.2 1.1 1 0 0 1 1 1 1 Phosphate transporter family HTH_IclR PF09339.5 GAP93064.1 - 0.11 12.0 0.2 0.52 9.9 0.0 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain FAD_binding_4 PF01565.18 GAP93065.1 - 1.4e-15 57.0 7.0 3.4e-15 55.7 4.9 1.7 1 0 0 1 1 1 1 FAD binding domain Pribosyltran PF00156.22 GAP93065.1 - 2.7e-15 56.1 1.1 4.6e-15 55.4 0.2 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Methyltransf_23 PF13489.1 GAP93065.1 - 1.6e-06 27.9 0.0 9.6e-06 25.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain P-mevalo_kinase PF04275.9 GAP93065.1 - 8.9e-05 22.1 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 Phosphomevalonate kinase UPRTase PF14681.1 GAP93065.1 - 0.00042 19.5 0.1 0.0029 16.8 0.0 2.0 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase GHMP_kinases_C PF08544.8 GAP93065.1 - 0.15 12.3 2.2 0.23 11.7 0.0 2.5 2 0 0 2 2 2 0 GHMP kinases C terminal BBE PF08031.7 GAP93065.1 - 0.16 11.9 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like CENP-B_dimeris PF09026.5 GAP93065.1 - 0.21 11.8 2.9 0.45 10.7 2.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Mito_fiss_reg PF05308.6 GAP93066.1 - 5.5 6.2 17.8 3.3 7.0 0.6 2.4 2 0 0 2 2 2 0 Mitochondrial fission regulator Rhomboid PF01694.17 GAP93067.1 - 2.8e-34 118.2 12.3 2.8e-34 118.2 8.6 2.1 2 0 0 2 2 2 1 Rhomboid family DUF4381 PF14316.1 GAP93067.1 - 0.6 10.2 2.3 1.3 9.1 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Cnd3 PF12719.2 GAP93070.1 - 2.9e-93 312.1 2.1 4.5e-93 311.5 0.1 2.3 3 1 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 GAP93070.1 - 1.7e-11 44.2 11.3 1e-06 28.9 0.4 5.5 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.17 GAP93070.1 - 4e-08 32.6 5.4 0.43 10.7 0.0 7.0 6 0 0 6 6 6 1 HEAT repeat MMS19_N PF14500.1 GAP93070.1 - 0.0023 17.2 0.1 0.071 12.3 0.0 3.1 3 1 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II DUF1546 PF07571.8 GAP93070.1 - 0.0055 16.7 0.4 0.63 10.2 0.0 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1546) Vac14_Fab1_bd PF12755.2 GAP93070.1 - 0.07 13.5 0.0 0.98 9.8 0.0 2.9 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Tom37_C PF11801.3 GAP93070.1 - 0.15 11.9 0.9 0.68 9.7 0.1 2.4 3 0 0 3 3 3 0 Tom37 C-terminal domain HEAT_EZ PF13513.1 GAP93070.1 - 1.4 9.5 19.2 0.21 12.1 0.8 6.9 5 1 3 8 8 8 0 HEAT-like repeat RRM_1 PF00076.17 GAP93071.1 - 3.5e-59 196.3 0.0 5.3e-20 70.8 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP93071.1 - 5.9e-45 151.1 0.2 2.5e-14 53.0 0.0 5.6 6 0 0 6 6 6 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP93071.1 - 8.4e-18 63.9 0.0 1.3e-06 28.1 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CENP-B_dimeris PF09026.5 GAP93071.1 - 0.015 15.5 1.2 0.015 15.5 0.9 3.7 1 1 2 3 3 3 0 Centromere protein B dimerisation domain tRNA-synt_2b PF00587.20 GAP93073.1 - 1.6e-44 151.5 0.0 2.5e-44 150.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAP93073.1 - 1.5e-13 50.4 0.0 3.2e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 GAP93073.1 - 8.4e-13 47.9 0.0 1.7e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 GAP93073.1 - 4.3e-12 45.6 0.0 9.4e-12 44.5 0.0 1.6 1 0 0 1 1 1 1 TGS domain tRNA-synt_His PF13393.1 GAP93073.1 - 0.087 11.8 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Rax2 PF12768.2 GAP93074.1 - 0.0097 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity DUF3275 PF11679.3 GAP93074.1 - 0.15 11.6 0.6 0.24 10.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) PROL5-SMR PF15621.1 GAP93074.1 - 7.3 7.0 10.5 1.8 9.0 2.6 2.2 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family PX PF00787.19 GAP93075.1 - 1.1e-12 47.7 0.0 2.2e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 GAP93075.1 - 2.3e-05 23.9 2.1 4.7e-05 22.9 1.4 1.6 1 0 0 1 1 1 1 SNARE domain zf-C4H2 PF10146.4 GAP93075.1 - 0.2 11.6 1.6 0.34 10.9 0.8 1.6 2 0 0 2 2 2 0 Zinc finger-containing protein Hydrolase_3 PF08282.7 GAP93077.1 - 0.0069 15.9 0.1 0.01 15.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAP93077.1 - 0.0069 16.8 0.1 0.01 16.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAP93077.1 - 0.015 15.4 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 GAP93078.1 - 4.9e-21 74.8 0.0 1e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 GAP93078.1 - 7e-13 48.3 0.0 1.4e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 GAP93078.1 - 0.0031 17.9 0.0 0.0054 17.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAP93078.1 - 0.023 14.8 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Homeobox PF00046.24 GAP93080.1 - 5e-20 70.8 5.4 1e-19 69.8 3.8 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 GAP93080.1 - 0.00065 19.3 0.5 0.00065 19.3 0.4 2.1 2 0 0 2 2 2 1 Homeobox KN domain ADH_N PF08240.7 GAP93081.1 - 3e-09 36.6 0.0 1.3e-08 34.5 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAP93081.1 - 1e-05 25.0 2.3 2.6e-05 23.7 1.6 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GTP_EFTU PF00009.22 GAP93082.1 - 2.8e-37 127.9 0.1 5.2e-37 127.1 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 GAP93082.1 - 2.6e-35 120.3 0.2 6.2e-35 119.1 0.2 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 GAP93082.1 - 1.8e-09 37.5 0.2 4.4e-09 36.3 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAP93082.1 - 0.016 15.1 1.2 0.021 14.7 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Cofilin_ADF PF00241.15 GAP93083.1 - 3.5e-13 49.5 0.0 3.9e-13 49.4 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cupin_2 PF07883.6 GAP93084.1 - 1.6e-11 43.5 0.8 2.2e-11 43.0 0.5 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 GAP93084.1 - 9.7e-10 38.0 0.2 1.2e-09 37.7 0.1 1.1 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 GAP93084.1 - 0.0021 17.7 0.4 0.0031 17.1 0.2 1.3 1 1 0 1 1 1 1 Cupin Cupin_3 PF05899.7 GAP93084.1 - 0.0042 16.4 0.1 0.0074 15.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) GPI PF06560.6 GAP93084.1 - 0.052 12.5 0.0 0.066 12.2 0.0 1.1 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Adaptin_binding PF10199.4 GAP93085.1 - 1.9e-12 47.6 5.9 4.9e-12 46.3 4.1 1.7 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 CagY_I PF14585.1 GAP93085.1 - 0.022 14.6 1.1 0.056 13.3 0.7 1.6 1 0 0 1 1 1 0 CagY type 1 repeat Bac_rhamnosid PF05592.6 GAP93086.1 - 2.6e-181 603.2 0.3 3.3e-181 602.9 0.2 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 GAP93086.1 - 1.1e-57 194.2 0.1 2e-57 193.4 0.1 1.4 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain FAD_binding_3 PF01494.14 GAP93088.1 - 1.3e-25 90.2 0.9 5.9e-25 88.0 0.6 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAP93088.1 - 1e-08 34.4 3.7 1.8e-06 27.1 0.7 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAP93088.1 - 1.4e-05 25.4 0.2 0.00012 22.4 0.2 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAP93088.1 - 2.1e-05 24.4 0.7 4.8e-05 23.3 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAP93088.1 - 0.00011 20.8 0.2 0.019 13.4 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 GAP93088.1 - 0.00043 20.2 1.2 0.00066 19.6 0.5 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAP93088.1 - 0.0006 18.5 2.5 0.37 9.3 0.3 2.1 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.19 GAP93088.1 - 0.002 17.0 0.1 0.0028 16.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.11 GAP93088.1 - 0.0033 16.8 0.1 0.0068 15.8 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 GAP93088.1 - 0.0056 16.7 0.0 0.013 15.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 GAP93088.1 - 0.0085 15.4 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 GAP93088.1 - 0.0087 15.7 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.12 GAP93088.1 - 0.014 14.4 0.1 0.029 13.4 0.0 1.5 2 0 0 2 2 2 0 Thi4 family NAD_binding_7 PF13241.1 GAP93088.1 - 0.019 15.2 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_oxidored PF12831.2 GAP93088.1 - 0.021 13.9 0.2 0.029 13.4 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 GAP93088.1 - 0.028 14.0 0.1 0.044 13.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 GAP93088.1 - 0.045 13.3 0.1 0.077 12.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_4 PF01565.18 GAP93089.1 - 4.9e-21 74.6 1.4 1e-20 73.6 1.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP93089.1 - 1.7e-05 24.6 0.0 4.5e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like UbiA PF01040.13 GAP93090.1 - 3.6e-27 95.1 22.4 5e-27 94.7 15.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family FAD_binding_4 PF01565.18 GAP93091.1 - 2.5e-27 95.0 1.4 4.1e-27 94.3 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP93091.1 - 2.3e-06 27.4 0.4 2.3e-06 27.4 0.3 1.9 2 0 0 2 2 2 1 Berberine and berberine like GMC_oxred_N PF00732.14 GAP93093.1 - 7.9e-37 127.0 0.0 6.7e-36 123.9 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAP93093.1 - 9.8e-35 119.9 0.0 1.4e-34 119.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAP93093.1 - 0.032 13.0 0.2 3.1 6.5 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain UCR_Fe-S_N PF10399.4 GAP93093.1 - 0.11 11.6 0.2 0.25 10.5 0.1 1.6 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Dyp_perox PF04261.7 GAP93094.1 - 1.6e-91 306.3 0.0 1.8e-91 306.1 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family Fungal_trans_2 PF11951.3 GAP93095.1 - 1.1e-18 67.0 0.3 1.8e-18 66.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Octopine_DH PF02317.12 GAP93096.1 - 0.022 14.4 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain DUF466 PF04328.8 GAP93098.1 - 0.48 10.2 2.6 1.2 8.9 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF466) ketoacyl-synt PF00109.21 GAP93101.1 - 8.2e-72 241.7 0.4 2e-71 240.4 0.3 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 GAP93101.1 - 8.2e-52 175.4 2.6 1e-51 175.2 0.4 2.2 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 GAP93101.1 - 9.2e-48 163.2 0.2 1.7e-47 162.2 0.2 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 GAP93101.1 - 1.7e-45 154.8 0.2 5e-45 153.4 0.1 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAP93101.1 - 4.9e-30 103.8 0.0 1.3e-29 102.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 GAP93101.1 - 6.5e-24 84.6 1.1 2.1e-23 82.9 0.8 2.0 1 1 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.7 GAP93101.1 - 7.4e-17 61.6 0.0 1.9e-16 60.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP93101.1 - 1.5e-13 51.0 0.0 4.2e-13 49.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP93101.1 - 3.6e-13 49.5 0.0 7.9e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain p450 PF00067.17 GAP93101.1 - 1.3e-10 40.4 0.0 8e-05 21.3 0.1 2.1 2 0 0 2 2 2 2 Cytochrome P450 Methyltransf_18 PF12847.2 GAP93101.1 - 4.1e-10 40.2 0.0 1.5e-09 38.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP93101.1 - 4e-08 32.9 0.0 8.1e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_4 PF07993.7 GAP93101.1 - 4.1e-06 25.8 0.0 0.0001 21.3 0.0 2.6 3 0 0 3 3 3 1 Male sterility protein Thiolase_N PF00108.18 GAP93101.1 - 0.00019 20.4 0.0 0.00039 19.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 GAP93101.1 - 0.0011 18.1 0.0 0.0023 17.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 GAP93101.1 - 0.0046 17.1 0.3 0.013 15.7 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site RrnaAD PF00398.15 GAP93101.1 - 0.19 10.7 0.0 0.35 9.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase HNH_2 PF13391.1 GAP93102.1 - 1.6e-14 53.4 0.2 8.9e-13 47.8 0.0 2.8 2 0 0 2 2 2 1 HNH endonuclease HNH_4 PF13395.1 GAP93102.1 - 0.15 11.7 0.0 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 HNH endonuclease HET PF06985.6 GAP93106.1 - 1e-27 97.0 0.2 5.7e-27 94.5 0.1 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_cc PF11790.3 GAP93108.1 - 7.8e-23 81.1 0.2 1e-22 80.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Vps54 PF07928.7 GAP93109.1 - 2.8e-43 147.2 0.2 8.3e-43 145.7 0.0 2.0 2 0 0 2 2 2 1 Vps54-like protein DUF2450 PF10475.4 GAP93109.1 - 1.4e-08 34.0 1.0 1.4e-08 34.0 0.7 2.2 3 0 0 3 3 3 1 Protein of unknown function N-terminal domain (DUF2450) DUF3490 PF11995.3 GAP93109.1 - 0.0037 16.8 2.4 0.22 11.0 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3490) Sec8_exocyst PF04048.9 GAP93109.1 - 0.0076 15.8 1.3 0.56 9.8 0.3 3.0 2 1 0 2 2 2 1 Sec8 exocyst complex component specific domain COG2 PF06148.6 GAP93109.1 - 6.8 6.5 8.8 0.41 10.5 0.4 3.1 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 MCM PF00493.18 GAP93110.1 - 4.3e-141 469.5 0.0 7e-141 468.8 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 GAP93110.1 - 1.4e-18 67.4 1.0 3e-18 66.4 0.5 1.8 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 GAP93110.1 - 2e-06 27.1 0.0 0.0002 20.6 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 GAP93110.1 - 1.6e-05 24.6 0.0 3.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 GAP93110.1 - 0.00051 19.6 0.0 0.0019 17.8 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 GAP93110.1 - 0.012 15.8 0.1 0.13 12.4 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 GAP93110.1 - 0.038 13.4 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AMP-binding PF00501.23 GAP93111.1 - 4.4e-18 64.8 0.3 7e-18 64.2 0.2 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Aldedh PF00171.17 GAP93112.1 - 1.1e-153 511.9 0.1 1.2e-153 511.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.13 GAP93113.1 - 1.3e-18 66.8 0.3 3.7e-18 65.3 0.2 1.7 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP93113.1 - 9.8e-08 31.7 9.7 1.7e-07 31.0 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amino_oxidase PF01593.19 GAP93114.1 - 2.1e-41 142.4 0.1 3.1e-25 89.1 0.0 2.0 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAP93114.1 - 1.7e-15 56.7 0.1 4.3e-15 55.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAP93114.1 - 2.4e-09 36.5 0.2 6.4e-08 31.8 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAP93114.1 - 1.4e-07 30.7 3.0 2.9e-07 29.7 2.1 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 GAP93114.1 - 7.3e-07 28.6 4.3 9.5e-07 28.2 2.9 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAP93114.1 - 1e-06 28.0 0.4 1.8e-06 27.2 0.3 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 GAP93114.1 - 1.1e-06 28.8 0.6 2.8e-06 27.5 0.4 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAP93114.1 - 2.5e-06 26.2 0.6 4.4e-06 25.4 0.3 1.4 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 GAP93114.1 - 1e-05 24.6 0.8 0.00025 20.0 0.5 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 GAP93114.1 - 1.3e-05 25.1 0.0 3e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAP93114.1 - 8.2e-05 22.9 0.3 0.00019 21.7 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAP93114.1 - 0.00027 19.9 1.3 0.00044 19.2 0.9 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 GAP93114.1 - 0.0029 16.7 0.4 0.0046 16.0 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 GAP93114.1 - 0.0055 16.3 0.5 0.0099 15.5 0.4 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 GAP93114.1 - 0.15 11.5 2.0 0.15 11.6 0.3 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2OG-FeII_Oxy_3 PF13640.1 GAP93115.1 - 0.013 15.9 0.0 0.023 15.1 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-Fe_Oxy_2 PF10014.4 GAP93115.1 - 0.095 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe dioxygenase 2OG-FeII_Oxy_3 PF13640.1 GAP93116.1 - 0.0011 19.4 0.0 0.002 18.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-Fe_Oxy_2 PF10014.4 GAP93116.1 - 0.014 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe dioxygenase DCP2 PF05026.8 GAP93116.1 - 0.17 11.7 1.1 0.68 9.8 0.2 2.2 2 0 0 2 2 2 0 Dcp2, box A domain AA_permease PF00324.16 GAP93117.1 - 1.3e-90 304.0 39.6 1.7e-90 303.7 27.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAP93117.1 - 4.7e-23 81.4 44.2 5.9e-23 81.0 30.6 1.0 1 0 0 1 1 1 1 Amino acid permease NPCC PF08058.6 GAP93119.1 - 9.1e-10 38.5 0.0 1.1e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore complex component DNA_binding_1 PF01035.15 GAP93121.1 - 6.3e-27 93.1 0.2 1.1e-26 92.3 0.0 1.5 2 0 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain HpaP PF09483.5 GAP93121.1 - 0.041 13.8 7.1 0.057 13.3 4.9 1.2 1 0 0 1 1 1 0 Type III secretion protein (HpaP) MFS_1 PF07690.11 GAP93123.1 - 3.1e-15 55.7 16.3 1e-14 54.0 11.0 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP93123.1 - 4.4e-09 35.4 0.9 4.4e-09 35.4 0.6 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter DUF2681 PF10883.3 GAP93123.1 - 8.4 6.6 5.4 16 5.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) ubiquitin PF00240.18 GAP93124.1 - 0.0026 17.1 0.0 0.0041 16.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family zf-C2H2_4 PF13894.1 GAP93125.1 - 0.00029 20.9 16.9 0.15 12.4 0.6 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger DUF629 PF04780.7 GAP93125.1 - 0.0037 15.8 2.8 0.0037 15.8 2.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.2 GAP93125.1 - 0.014 15.4 2.7 0.075 13.1 0.2 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 GAP93125.1 - 0.057 13.7 6.2 9.8 6.6 0.1 3.7 3 0 0 3 3 3 0 Zinc-finger double domain DTHCT PF08070.6 GAP93125.1 - 6.1 7.5 10.3 0.2 12.3 1.6 2.2 2 0 0 2 2 2 0 DTHCT (NUC029) region DUF4232 PF14016.1 GAP93127.1 - 0.018 14.7 8.5 0.12 12.0 1.7 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4232) Nop PF01798.13 GAP93128.1 - 1.2e-52 177.1 2.9 1.9e-51 173.2 2.0 2.5 1 1 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 GAP93128.1 - 6.5e-26 89.8 0.8 1.2e-25 89.0 0.1 1.8 2 0 0 2 2 2 1 NOSIC (NUC001) domain NOP5NT PF08156.8 GAP93128.1 - 6.9e-19 67.7 0.6 1.9e-18 66.3 0.5 1.8 1 0 0 1 1 1 1 NOP5NT (NUC127) domain vATP-synt_AC39 PF01992.11 GAP93129.1 - 5e-118 394.0 0.0 5.6e-118 393.9 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Ribosomal_S15 PF00312.17 GAP93130.1 - 2.1e-15 56.2 1.0 4.8e-15 55.0 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S15 Ribosomal_S2 PF00318.15 GAP93131.1 - 2.9e-42 144.2 0.0 4.2e-22 78.4 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 p450 PF00067.17 GAP93132.1 - 9.3e-26 90.3 0.0 1.4e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 RasGEF PF00617.14 GAP93133.1 - 1.7e-48 164.8 0.1 2.6e-48 164.2 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAP93133.1 - 2.5e-16 59.6 0.4 5.6e-16 58.5 0.3 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Peptidase_M36 PF02128.10 GAP93134.1 - 2.6e-138 460.9 2.6 3.3e-138 460.6 1.8 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 GAP93134.1 - 1.2e-10 40.6 3.5 2.5e-10 39.6 2.4 1.6 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif ADH_N PF08240.7 GAP93135.1 - 2.6e-20 72.1 1.3 5.4e-20 71.1 0.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAP93135.1 - 6.5e-20 71.0 5.0 8.7e-20 70.5 2.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAP93135.1 - 0.0006 20.7 2.7 0.0011 19.8 1.9 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase BTB_2 PF02214.17 GAP93136.1 - 3.7e-07 30.2 0.0 0.00087 19.4 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain HET PF06985.6 GAP93137.1 - 5.4e-22 78.4 0.0 1e-21 77.5 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PhyH PF05721.8 GAP93138.1 - 1.3e-09 38.4 0.1 1.7e-09 38.0 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PAP2 PF01569.16 GAP93139.1 - 4.2e-18 65.2 2.2 4.2e-18 65.2 1.5 2.0 2 0 0 2 2 2 1 PAP2 superfamily adh_short PF00106.20 GAP93140.1 - 2.6e-19 69.7 0.1 3.9e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAP93140.1 - 2.1e-07 30.8 0.0 3e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 KR domain TIR-like PF10137.4 GAP93140.1 - 5.2e-05 22.8 0.0 7.6e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Predicted nucleotide-binding protein containing TIR-like domain adh_short_C2 PF13561.1 GAP93140.1 - 0.0013 18.5 0.0 0.0018 18.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAP93140.1 - 0.0017 18.4 0.0 0.0076 16.2 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAP93140.1 - 0.027 13.8 0.0 0.052 12.9 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 GAP93140.1 - 0.16 11.0 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FAD_binding_4 PF01565.18 GAP93141.1 - 1.8e-15 56.6 1.4 1.8e-15 56.6 1.0 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 GAP93141.1 - 2.6e-10 40.0 0.7 6.7e-10 38.7 0.5 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 GAP93141.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding TPR_12 PF13424.1 GAP93142.1 - 3.8e-68 225.4 15.8 2.2e-19 69.1 0.3 6.0 3 2 2 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 GAP93142.1 - 6.6e-60 197.4 12.3 1.5e-08 34.2 0.2 8.3 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_11 PF13414.1 GAP93142.1 - 6.9e-39 131.3 37.7 1.9e-10 40.2 0.8 4.7 1 1 6 7 7 7 7 TPR repeat TPR_1 PF00515.23 GAP93142.1 - 4.8e-38 127.2 21.6 2.8e-06 26.6 0.2 8.4 8 1 0 8 8 8 7 Tetratricopeptide repeat TPR_7 PF13176.1 GAP93142.1 - 4.7e-27 91.6 6.8 0.00087 18.9 0.1 8.0 7 0 0 7 7 7 7 Tetratricopeptide repeat HET PF06985.6 GAP93142.1 - 1.4e-21 77.0 1.8 6.3e-20 71.7 1.3 2.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_2 PF07719.12 GAP93142.1 - 3e-21 73.5 23.1 0.0011 18.7 0.2 8.7 8 2 0 8 8 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 GAP93142.1 - 5.9e-21 73.0 8.4 0.055 14.1 0.0 8.7 7 2 2 9 9 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 GAP93142.1 - 3.3e-18 64.2 5.6 0.26 11.5 0.0 8.4 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 GAP93142.1 - 7.2e-17 59.8 25.2 0.0018 17.9 0.2 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 GAP93142.1 - 5.8e-14 52.3 14.3 0.00043 20.8 0.2 5.7 2 1 5 7 7 6 6 Tetratricopeptide repeat NB-ARC PF00931.17 GAP93142.1 - 8.9e-14 51.0 0.0 1.4e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.1 GAP93142.1 - 4.4e-09 36.5 11.3 0.055 13.8 0.3 5.1 3 1 2 5 5 5 3 Tetratricopeptide repeat 14-3-3 PF00244.15 GAP93142.1 - 2.8e-08 33.1 2.2 0.0031 16.6 0.0 4.2 1 1 5 6 6 6 3 14-3-3 protein DUF2225 PF09986.4 GAP93142.1 - 4.9e-08 32.7 2.8 0.11 11.9 0.0 3.5 1 1 3 4 4 4 4 Uncharacterized protein conserved in bacteria (DUF2225) AAA_16 PF13191.1 GAP93142.1 - 3.9e-07 30.2 0.7 4.7e-06 26.7 0.8 2.7 2 1 0 2 2 2 1 AAA ATPase domain TPR_4 PF07721.9 GAP93142.1 - 1.2e-06 28.3 0.0 12 6.6 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAP93142.1 - 1.7e-06 28.0 19.7 0.88 10.1 0.1 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat Arch_ATPase PF01637.13 GAP93142.1 - 2.5e-06 27.3 0.0 5.1e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase SNAP PF14938.1 GAP93142.1 - 4.6e-06 25.9 0.0 0.0021 17.2 0.0 2.3 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP PPR PF01535.15 GAP93142.1 - 0.00016 21.4 3.5 26 5.0 0.0 6.0 6 0 0 6 6 6 0 PPR repeat Tcf25 PF04910.9 GAP93142.1 - 0.00024 20.1 0.3 2.1 7.2 0.0 4.3 2 1 3 5 5 5 1 Transcriptional repressor TCF25 RPN7 PF10602.4 GAP93142.1 - 0.0014 18.0 1.5 5.1 6.4 0.0 4.5 3 3 2 5 5 5 0 26S proteasome subunit RPN7 AAA_22 PF13401.1 GAP93142.1 - 0.0018 18.4 0.0 0.009 16.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 GAP93142.1 - 0.011 15.5 0.0 0.031 14.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.12 GAP93142.1 - 0.014 14.8 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF3366 PF11846.3 GAP93142.1 - 0.035 13.9 0.0 5.2 6.8 0.0 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF3366) Mad3_BUB1_I PF08311.7 GAP93142.1 - 0.055 13.2 1.0 11 5.8 0.0 4.0 4 0 0 4 4 3 0 Mad3/BUB1 homology region 1 Spatacsin_C PF14649.1 GAP93142.1 - 0.07 11.9 0.7 0.27 10.0 0.1 2.0 1 1 2 3 3 3 0 Spatacsin C-terminus Phage_T4_Ndd PF06591.6 GAP93142.1 - 0.094 12.2 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) TPR_21 PF09976.4 GAP93142.1 - 0.59 10.0 2.2 1.2e+02 2.5 0.1 4.5 5 1 0 5 5 5 0 Tetratricopeptide repeat Ank_2 PF12796.2 GAP93143.1 - 1.4e-120 393.9 13.6 6.3e-16 58.4 0.0 20.4 9 6 6 17 17 17 16 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAP93143.1 - 6.4e-90 294.1 34.2 5.5e-07 29.9 0.0 28.2 17 8 13 30 30 28 21 Ankyrin repeats (many copies) Ank PF00023.25 GAP93143.1 - 9.5e-83 268.1 56.5 2.4e-07 30.1 0.0 30.5 29 3 1 30 30 29 16 Ankyrin repeat Ank_5 PF13857.1 GAP93143.1 - 6.6e-63 207.3 48.4 2.7e-06 27.4 0.0 25.6 18 6 7 26 26 26 17 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP93143.1 - 5.5e-62 199.5 19.9 3.8e-05 23.5 0.0 28.8 29 2 1 30 30 29 8 Ankyrin repeat NACHT PF05729.7 GAP93143.1 - 9.9e-10 38.3 0.0 2.4e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 GAP93143.1 - 0.00082 19.4 0.1 0.0047 16.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAP93143.1 - 0.016 15.3 0.0 0.43 10.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF2735 PF10931.3 GAP93143.1 - 0.025 14.8 0.0 0.067 13.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2735) AAA_19 PF13245.1 GAP93143.1 - 0.028 14.1 0.6 1.1 9.0 0.0 3.3 4 0 0 4 4 3 0 Part of AAA domain DUF2075 PF09848.4 GAP93143.1 - 0.031 13.2 0.0 0.054 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 GAP93143.1 - 0.089 13.1 0.0 2.3 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 GAP93143.1 - 0.19 11.3 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_helicase PF00910.17 GAP93143.1 - 0.22 11.6 0.0 0.54 10.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 GAP93143.1 - 0.52 9.1 0.0 1 8.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNase_H PF00075.19 GAP93144.1 - 3.6e-19 69.4 0.0 5.3e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 GAP93144.1 - 2.3e-05 24.0 0.1 0.023 14.4 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase-like Glyco_hydro_61 PF03443.9 GAP93146.1 - 1.2e-29 103.6 0.0 2.3e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 APC8 PF04049.8 GAP93147.1 - 2e-47 160.4 0.4 4.5e-47 159.3 0.0 1.7 2 0 0 2 2 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 GAP93147.1 - 1.5e-17 62.4 7.7 0.00054 19.4 0.0 6.1 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 GAP93147.1 - 2.6e-16 58.9 7.1 3.1e-06 26.7 0.1 6.0 4 1 2 6 6 6 3 TPR repeat TPR_8 PF13181.1 GAP93147.1 - 4e-12 44.9 8.7 0.00025 20.5 0.0 6.1 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAP93147.1 - 2.9e-11 42.3 20.0 0.24 11.4 0.0 9.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 GAP93147.1 - 2.4e-09 36.9 10.6 0.024 15.2 0.0 7.1 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAP93147.1 - 3.5e-09 36.4 16.0 0.00017 21.4 0.6 6.0 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAP93147.1 - 2.5e-07 31.1 20.2 2.8e-05 24.6 0.4 7.3 6 2 3 9 9 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAP93147.1 - 5.2e-07 29.8 3.5 1.6 9.1 0.0 5.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAP93147.1 - 6.5e-07 28.6 7.6 0.15 11.9 0.0 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat Apc3 PF12895.2 GAP93147.1 - 1.3e-06 28.4 3.2 0.056 13.5 0.0 4.7 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.2 GAP93147.1 - 0.0008 19.2 1.6 0.017 14.9 0.1 2.9 1 1 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_17 PF13431.1 GAP93147.1 - 0.00096 19.1 1.0 2.5 8.5 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 GAP93147.1 - 0.0021 17.9 15.3 0.0097 15.7 0.1 4.6 6 0 0 6 6 5 2 Tetratricopeptide repeat ChAPs PF09295.5 GAP93147.1 - 0.014 14.2 0.0 3.2 6.4 0.0 2.2 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF2424 PF10340.4 GAP93147.1 - 0.041 12.5 0.0 0.064 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) MIT PF04212.13 GAP93147.1 - 0.33 10.8 0.0 0.33 10.8 0.0 2.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_15 PF13429.1 GAP93147.1 - 0.48 9.4 10.6 0.37 9.8 3.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.7 GAP93147.1 - 1.9 9.2 14.1 16 6.2 0.2 5.1 4 0 0 4 4 4 0 Sel1 repeat polyprenyl_synt PF00348.12 GAP93148.1 - 6.1e-72 241.5 0.0 7.2e-72 241.3 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase p450 PF00067.17 GAP93149.1 - 3.9e-31 108.0 0.0 9.8e-25 86.9 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 PH PF00169.24 GAP93150.1 - 0.0059 16.7 0.7 0.014 15.5 0.5 1.6 1 0 0 1 1 1 1 PH domain RA PF00788.18 GAP93150.1 - 0.022 15.2 0.1 0.06 13.8 0.1 1.7 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain TMEM154 PF15102.1 GAP93151.1 - 0.0053 16.4 1.0 0.023 14.4 0.7 2.1 1 1 0 1 1 1 1 TMEM154 protein family DUF1191 PF06697.7 GAP93151.1 - 0.029 13.1 0.1 0.053 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) TMEM51 PF15345.1 GAP93151.1 - 0.047 13.3 0.2 0.072 12.7 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 DUF1049 PF06305.6 GAP93151.1 - 0.087 12.3 0.3 0.17 11.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF2076 PF09849.4 GAP93151.1 - 0.1 12.5 5.1 0.14 12.1 3.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Podoplanin PF05808.6 GAP93151.1 - 0.22 11.0 11.9 0.63 9.5 8.2 1.8 1 1 0 1 1 1 0 Podoplanin PAP1 PF08601.5 GAP93151.1 - 2.1 7.9 6.5 3 7.4 4.5 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 MSP1_C PF07462.6 GAP93151.1 - 6.6 4.9 5.2 11 4.3 3.6 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus RmlD_sub_bind PF04321.12 GAP93152.1 - 7.2e-54 182.6 0.0 8.8e-54 182.3 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 GAP93152.1 - 1.2e-21 77.2 0.0 4.7e-21 75.3 0.0 1.7 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAP93152.1 - 4.6e-09 35.5 0.0 2.4e-06 26.6 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 GAP93152.1 - 2.9e-07 29.6 0.6 6.5e-05 21.9 0.1 3.0 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 GAP93152.1 - 6.6e-07 28.3 0.0 1.7e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAP93152.1 - 1.6e-05 25.0 0.1 2.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 GAP93152.1 - 0.0045 16.9 3.3 0.13 12.1 0.9 2.7 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 GAP93152.1 - 0.07 12.3 0.0 0.64 9.2 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family KR PF08659.5 GAP93152.1 - 0.098 12.3 0.0 11 5.5 0.0 2.4 2 0 0 2 2 2 0 KR domain GDPD_2 PF13653.1 GAP93153.1 - 0.12 12.6 0.1 0.12 12.6 0.1 2.5 3 0 0 3 3 3 0 Glycerophosphoryl diester phosphodiesterase family B-block_TFIIIC PF04182.7 GAP93155.1 - 3e-13 49.3 0.0 6.5e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC Amino_oxidase PF01593.19 GAP93156.1 - 1.1e-40 140.0 0.1 1.8e-40 139.3 0.1 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAP93156.1 - 7.1e-13 48.3 0.4 1.9e-12 47.0 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAP93156.1 - 3.3e-06 26.2 1.2 4.7e-06 25.7 0.3 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAP93156.1 - 9.9e-06 25.7 0.2 0.00041 20.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAP93156.1 - 7.9e-05 21.8 0.5 0.00024 20.2 0.0 2.0 3 0 0 3 3 3 1 FAD binding domain FAD_binding_2 PF00890.19 GAP93156.1 - 8.1e-05 21.6 0.1 0.00021 20.2 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 GAP93156.1 - 0.0001 21.4 0.1 0.00018 20.6 0.1 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 GAP93156.1 - 0.0031 16.0 0.1 0.0065 14.9 0.1 1.6 1 1 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 GAP93156.1 - 0.0052 15.9 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAP93156.1 - 0.0093 16.3 0.4 0.025 14.9 0.3 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAP93156.1 - 0.043 13.7 0.1 0.27 11.0 0.1 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 GAP93156.1 - 0.12 11.8 0.4 0.27 10.6 0.2 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 GAP93156.1 - 0.14 10.9 0.0 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HNH_2 PF13391.1 GAP93158.1 - 3.2e-10 39.6 0.0 6.4e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease p450 PF00067.17 GAP93160.1 - 3.8e-45 154.2 0.0 4.8e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Monellin PF09200.5 GAP93160.1 - 0.099 12.3 0.4 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 Monellin Shisa PF13908.1 GAP93161.1 - 0.47 10.6 2.4 8.3 6.5 0.2 2.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator MFS_1 PF07690.11 GAP93162.1 - 3.4e-38 131.2 43.8 1.9e-37 128.8 30.4 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP93162.1 - 1.4e-15 56.8 12.6 1.4e-15 56.8 8.8 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter ketoacyl-synt PF00109.21 GAP93163.1 - 4.2e-64 216.4 0.0 7.9e-64 215.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 GAP93163.1 - 3.2e-57 193.0 1.1 6.7e-57 192.0 0.7 1.6 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 GAP93163.1 - 1.3e-52 179.0 0.2 8.8e-52 176.4 0.0 2.4 3 0 0 3 3 3 1 Acyl transferase domain adh_short PF00106.20 GAP93163.1 - 4.9e-46 156.6 0.6 4.9e-46 156.6 0.4 2.2 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 GAP93163.1 - 7.5e-39 133.6 0.8 2.7e-38 131.8 0.2 2.2 2 0 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 GAP93163.1 - 1.9e-38 130.9 0.0 6.2e-38 129.3 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 GAP93163.1 - 5.5e-18 64.7 0.2 3.1e-17 62.3 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 GAP93163.1 - 9.5e-17 61.3 0.0 3e-16 59.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP93163.1 - 1.1e-13 51.2 0.0 2.7e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP93163.1 - 3.2e-12 46.3 0.0 7.4e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 GAP93163.1 - 3.7e-12 47.2 0.0 1.6e-11 45.1 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 GAP93163.1 - 5.5e-12 46.2 0.0 9.4e-10 39.0 0.0 3.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP93163.1 - 8.3e-10 39.0 0.0 3.1e-09 37.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 GAP93163.1 - 7.5e-07 29.3 0.0 3.1e-06 27.3 0.0 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site ACP_syn_III PF08545.5 GAP93163.1 - 0.00039 20.0 0.6 0.0011 18.5 0.4 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Epimerase PF01370.16 GAP93163.1 - 0.0008 18.9 0.0 0.002 17.5 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ubie_methyltran PF01209.13 GAP93163.1 - 0.00081 18.5 0.0 0.0072 15.4 0.0 2.3 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family ADH_N PF08240.7 GAP93163.1 - 0.00094 18.9 0.2 0.0021 17.8 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Saccharop_dh PF03435.13 GAP93163.1 - 0.001 18.1 0.0 0.0023 16.9 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase Methyltransf_28 PF02636.12 GAP93163.1 - 0.0029 17.0 0.0 0.012 15.0 0.0 2.0 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase tRNA-synt_1b PF00579.20 GAP93165.1 - 1.1e-30 106.8 0.0 1.4e-30 106.4 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) adh_short PF00106.20 GAP93166.1 - 5e-19 68.8 17.5 7.4e-16 58.5 4.4 3.1 3 0 0 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.1 GAP93166.1 - 1.1e-14 54.8 0.7 6.2e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP93166.1 - 6.1e-10 39.0 3.2 6.1e-10 39.0 2.2 1.8 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 GAP93166.1 - 0.0061 15.4 0.1 0.0089 14.9 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 GAP93166.1 - 0.023 14.7 0.4 0.041 13.9 0.3 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Dak1_2 PF13684.1 GAP93166.1 - 0.071 12.0 0.1 0.097 11.5 0.1 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family 3Beta_HSD PF01073.14 GAP93166.1 - 0.12 11.1 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Thymidylate_kin PF02223.12 GAP93167.1 - 4.5e-42 143.5 0.1 8.9e-41 139.3 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.1 GAP93167.1 - 0.00031 20.7 0.0 0.00057 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Pkinase PF00069.20 GAP93170.1 - 7e-34 117.1 0.0 1e-33 116.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP93170.1 - 5.7e-13 48.5 0.0 8.2e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAP93170.1 - 3e-05 23.1 0.0 0.00017 20.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 GAP93170.1 - 4.8e-05 23.1 0.0 8.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 GAP93170.1 - 0.0043 16.1 0.0 0.0079 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 GAP93170.1 - 0.0095 15.5 0.1 0.048 13.2 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 GAP93170.1 - 0.089 12.1 0.0 0.29 10.4 0.0 1.9 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Mt_ATP-synt_D PF05873.7 GAP93171.1 - 0.0089 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) NACHT PF05729.7 GAP93172.1 - 3.9e-09 36.3 0.1 1.1e-07 31.6 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 GAP93172.1 - 1.1e-05 25.5 0.0 6.5e-05 23.0 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 GAP93172.1 - 2e-05 24.6 0.8 0.00062 19.8 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain ABC_tran PF00005.22 GAP93172.1 - 0.0014 18.9 0.0 0.0067 16.7 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_17 PF13207.1 GAP93172.1 - 0.022 15.5 0.1 0.39 11.5 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 GAP93172.1 - 0.024 14.1 0.1 0.049 13.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 GAP93172.1 - 0.058 12.8 1.0 0.32 10.3 0.0 2.6 3 1 0 3 3 3 0 AAA-like domain AAA_23 PF13476.1 GAP93172.1 - 0.079 13.2 4.1 1.7 8.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF258 PF03193.11 GAP93172.1 - 0.12 11.5 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Terpene_synth_C PF03936.11 GAP93173.1 - 3.9e-10 39.4 0.8 6e-10 38.8 0.5 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain TRI5 PF06330.6 GAP93173.1 - 0.025 13.2 0.0 0.035 12.7 0.0 1.2 1 0 0 1 1 1 0 Trichodiene synthase (TRI5) CDC50 PF03381.10 GAP93174.1 - 1.8 7.6 4.2 2 7.4 0.7 2.1 2 0 0 2 2 2 0 LEM3 (ligand-effect modulator 3) family / CDC50 family Methyltransf_23 PF13489.1 GAP93175.1 - 4.7e-16 58.9 0.0 7.8e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP93175.1 - 2.5e-08 34.4 0.0 1.7e-07 31.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP93175.1 - 5e-08 33.3 0.0 9e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP93175.1 - 9e-07 29.2 0.0 1.9e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP93175.1 - 2.9e-06 26.9 0.0 1.1e-05 25.0 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAP93175.1 - 8.7e-05 21.6 0.0 0.00021 20.4 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 GAP93175.1 - 0.00023 20.5 0.0 0.001 18.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 GAP93175.1 - 0.0046 16.1 0.0 0.0071 15.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 GAP93175.1 - 0.0092 16.3 0.0 0.026 14.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 GAP93175.1 - 0.012 15.5 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.7 GAP93175.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_16 PF10294.4 GAP93175.1 - 0.018 14.5 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.13 GAP93175.1 - 0.054 12.6 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_26 PF13659.1 GAP93175.1 - 0.08 12.9 0.0 0.53 10.3 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain p450 PF00067.17 GAP93176.1 - 5.4e-47 160.3 0.0 7.5e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 GAP93177.1 - 7.3e-19 68.5 0.0 9e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP93177.1 - 2.4e-08 33.8 0.0 3.2e-08 33.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAP93177.1 - 0.091 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein GMC_oxred_N PF00732.14 GAP93178.1 - 4e-48 164.0 0.0 5.2e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAP93178.1 - 2.4e-33 115.4 0.0 4.2e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAP93178.1 - 1.3e-08 34.1 0.4 3.7e-07 29.3 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAP93178.1 - 2.7e-05 23.2 0.3 0.002 17.0 0.5 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 GAP93178.1 - 5.6e-05 23.1 0.0 0.00015 21.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAP93178.1 - 0.00014 20.9 0.2 0.0002 20.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 GAP93178.1 - 0.00017 21.5 0.2 0.00045 20.1 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAP93178.1 - 0.0011 18.1 0.2 0.0029 16.7 0.1 1.6 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.9 GAP93178.1 - 0.011 14.3 0.1 0.016 13.8 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 GAP93178.1 - 0.026 14.2 0.4 0.053 13.2 0.1 1.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAP93178.1 - 0.1 12.6 0.6 1.9 8.4 0.3 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAP93178.1 - 0.12 10.8 0.4 0.16 10.3 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein adh_short PF00106.20 GAP93179.1 - 8.4e-10 38.8 0.2 2.1e-09 37.5 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAP93179.1 - 3.5e-06 26.7 0.1 1.2e-05 25.0 0.1 1.8 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.7 GAP93179.1 - 0.0002 20.3 0.0 0.00082 18.3 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.16 GAP93179.1 - 0.055 12.9 0.0 0.14 11.5 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAP93179.1 - 0.086 12.8 0.2 0.21 11.5 0.1 1.7 1 0 0 1 1 1 0 NADH(P)-binding DUF1490 PF07371.7 GAP93179.1 - 0.16 11.9 0.3 0.69 9.9 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1490) Cupin_2 PF07883.6 GAP93180.1 - 1.1e-07 31.2 0.5 3e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Cupin domain FAD_binding_4 PF01565.18 GAP93181.1 - 4.6e-27 94.1 0.3 9e-27 93.2 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Ribosomal_L44 PF00935.14 GAP93181.1 - 0.22 11.5 4.0 0.41 10.7 2.8 1.3 1 0 0 1 1 1 0 Ribosomal protein L44 Hira PF07569.6 GAP93181.1 - 0.3 10.2 1.2 1.4 8.1 0.1 2.2 2 0 0 2 2 2 0 TUP1-like enhancer of split UbiA PF01040.13 GAP93182.1 - 2.3e-33 115.5 23.2 3e-33 115.1 16.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF716 PF04819.7 GAP93182.1 - 0.38 10.1 4.0 0.094 12.1 0.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF716) adh_short PF00106.20 GAP93183.1 - 6.5e-34 117.2 0.9 8.9e-34 116.8 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP93183.1 - 4.4e-13 49.5 0.1 5.9e-13 49.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP93183.1 - 2.9e-12 46.6 0.1 4.2e-12 46.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAP93183.1 - 2e-05 24.1 0.2 2.9e-05 23.6 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 GAP93183.1 - 0.00017 21.3 0.2 0.00029 20.5 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 GAP93183.1 - 0.00071 18.3 0.1 0.00097 17.9 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Kelch_4 PF13418.1 GAP93183.1 - 0.0075 16.0 0.8 0.038 13.7 0.1 2.4 2 0 0 2 2 2 1 Galactose oxidase, central domain NAD_binding_10 PF13460.1 GAP93183.1 - 0.0088 16.0 0.2 0.022 14.7 0.1 1.7 2 0 0 2 2 2 1 NADH(P)-binding UDPG_MGDP_dh_N PF03721.9 GAP93183.1 - 0.02 14.3 0.1 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Saccharop_dh PF03435.13 GAP93183.1 - 0.021 13.8 0.1 0.03 13.3 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase AlaDh_PNT_C PF01262.16 GAP93183.1 - 0.038 13.5 0.4 0.057 12.9 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 GAP93183.1 - 0.041 13.3 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 GAP93183.1 - 0.043 13.8 0.1 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NmrA PF05368.8 GAP93183.1 - 0.045 13.0 0.3 0.098 11.8 0.2 1.5 1 0 0 1 1 1 0 NmrA-like family 2-Hacid_dh_C PF02826.14 GAP93183.1 - 0.093 11.8 0.1 0.15 11.2 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 GAP93183.1 - 0.095 11.5 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Lipase_GDSL PF00657.17 GAP93185.1 - 7.9e-12 45.5 0.0 1e-11 45.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 GAP93185.1 - 5.8e-09 36.3 0.3 8.7e-09 35.7 0.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 GAP93185.1 - 0.076 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Metallophos PF00149.23 GAP93186.1 - 0.0017 17.7 3.1 0.0078 15.6 2.1 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAP93186.1 - 0.0035 17.1 0.0 0.0079 16.0 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SET PF00856.23 GAP93187.1 - 1.5e-11 44.8 0.0 4e-11 43.4 0.0 1.7 1 1 0 1 1 1 1 SET domain T2SG PF08334.6 GAP93187.1 - 0.055 13.2 0.2 0.19 11.5 0.1 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein G SAF PF08666.7 GAP93187.1 - 0.2 12.1 0.9 11 6.4 0.0 2.4 2 0 0 2 2 2 0 SAF domain GTP_cyclohydroI PF01227.17 GAP93188.1 - 1.5e-74 249.1 0.5 2.2e-74 248.6 0.3 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 GAP93188.1 - 0.00014 21.7 0.0 0.00033 20.5 0.0 1.6 1 0 0 1 1 1 1 QueF-like protein BAR PF03114.13 GAP93188.1 - 0.039 13.4 0.8 2.5 7.5 0.1 2.3 2 0 0 2 2 2 0 BAR domain TAFII28 PF04719.9 GAP93189.1 - 6.9e-19 67.4 0.0 6e-18 64.4 0.0 2.1 1 1 0 1 1 1 1 hTAFII28-like protein conserved region Caps_synth PF05704.7 GAP93190.1 - 1.6e-10 40.6 0.0 3e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 GAP93190.1 - 0.00014 22.1 0.0 0.00026 21.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Dioxygenase_C PF00775.16 GAP93192.1 - 5.3e-11 42.1 0.0 8.8e-11 41.3 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Methyltransf_11 PF08241.7 GAP93193.1 - 4.5e-24 84.7 0.0 9.7e-24 83.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP93193.1 - 3.5e-22 78.6 0.0 6e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP93193.1 - 1.1e-18 67.4 0.0 2.6e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP93193.1 - 1.7e-16 60.4 0.0 3.1e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP93193.1 - 2.8e-16 60.0 1.4 3.9e-16 59.6 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP93193.1 - 2.9e-14 53.1 0.0 7.3e-14 51.7 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP93193.1 - 1.8e-10 40.3 0.0 2.8e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 GAP93193.1 - 5.1e-09 36.1 1.1 7.9e-09 35.5 0.4 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAP93193.1 - 8.3e-09 35.0 0.1 1.8e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 GAP93193.1 - 4e-08 32.8 0.0 9.9e-08 31.5 0.0 1.6 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.6 GAP93193.1 - 1.6e-06 27.0 0.0 2.3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.12 GAP93193.1 - 3.5e-06 26.2 0.0 6.2e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 GAP93193.1 - 1.8e-05 24.3 0.0 2.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 GAP93193.1 - 0.00011 21.9 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 GAP93193.1 - 0.00011 21.5 0.0 0.39 9.9 0.0 2.2 2 0 0 2 2 2 2 CheR methyltransferase, SAM binding domain CMAS PF02353.15 GAP93193.1 - 0.0025 16.9 0.0 0.0038 16.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase UPF0020 PF01170.13 GAP93193.1 - 0.0035 16.9 0.0 0.006 16.1 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 FtsJ PF01728.14 GAP93193.1 - 0.037 14.0 0.0 0.052 13.5 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase DREV PF05219.7 GAP93193.1 - 0.038 12.8 0.0 0.49 9.2 0.0 2.0 1 1 0 1 1 1 0 DREV methyltransferase DUF938 PF06080.7 GAP93193.1 - 0.043 13.3 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FmrO PF07091.6 GAP93193.1 - 0.06 12.3 0.0 0.091 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) PrmA PF06325.8 GAP93193.1 - 0.094 11.8 0.1 0.23 10.5 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.6 GAP93193.1 - 0.14 11.5 0.0 0.44 9.9 0.0 1.8 2 0 0 2 2 2 0 Nodulation protein S (NodS) RrnaAD PF00398.15 GAP93193.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Glyco_hydro_16 PF00722.16 GAP93194.1 - 7.7e-08 31.8 0.1 2.3e-06 27.0 0.0 2.4 3 0 0 3 3 3 1 Glycosyl hydrolases family 16 BAF1_ABF1 PF04684.8 GAP93194.1 - 4.1 6.1 18.1 5.5 5.7 12.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Arm PF00514.18 GAP93195.1 - 9.1e-67 218.8 30.3 2.8e-11 42.7 0.1 11.0 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 GAP93195.1 - 4e-22 78.2 12.3 9.2e-07 29.0 0.3 7.5 3 2 2 6 6 6 5 HEAT repeats HEAT PF02985.17 GAP93195.1 - 2.3e-16 58.3 16.3 0.014 15.4 0.1 9.4 10 0 0 10 10 10 5 HEAT repeat HEAT_EZ PF13513.1 GAP93195.1 - 3e-15 56.1 11.6 0.00014 22.2 0.1 7.8 6 2 3 9 9 9 4 HEAT-like repeat Adaptin_N PF01602.15 GAP93195.1 - 1.7e-10 39.8 11.6 4.2e-08 31.9 3.5 2.8 2 1 2 4 4 4 3 Adaptin N terminal region Arm_2 PF04826.8 GAP93195.1 - 4.5e-10 39.0 7.2 0.0016 17.5 0.2 3.3 1 1 1 3 3 3 3 Armadillo-like V-ATPase_H_N PF03224.9 GAP93195.1 - 1.5e-08 34.1 1.8 0.0017 17.5 0.4 3.7 2 1 1 3 3 3 2 V-ATPase subunit H KAP PF05804.7 GAP93195.1 - 1.2e-07 30.0 0.8 2.2e-07 29.2 0.5 1.5 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) DUF2454 PF10521.4 GAP93195.1 - 0.0015 17.5 0.6 0.014 14.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2454) DUF908 PF06012.7 GAP93195.1 - 0.0016 17.8 1.7 1.9 7.7 0.1 3.8 1 1 2 4 4 4 1 Domain of Unknown Function (DUF908) HEAT_PBS PF03130.11 GAP93195.1 - 0.006 16.9 5.9 18 6.1 0.1 6.7 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Vpu PF00558.14 GAP93195.1 - 0.05 13.1 0.9 0.14 11.7 0.2 2.0 2 0 0 2 2 2 0 Vpu protein Vac14_Fab1_bd PF12755.2 GAP93195.1 - 0.086 13.2 0.1 4.5 7.7 0.0 3.2 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region Peptidase_S26 PF10502.4 GAP93196.1 - 4.4e-07 29.4 0.0 6.9e-07 28.8 0.0 1.4 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 GAP93196.1 - 4.6e-06 26.1 0.0 8.3e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like IF3_C PF00707.17 GAP93198.1 - 6.5e-08 32.2 0.0 1.1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 GAP93198.1 - 0.00021 20.6 0.0 0.00041 19.7 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial translation initiation factor Transglut_core3 PF13471.1 GAP93198.1 - 0.22 11.2 2.6 0.25 11.1 0.1 2.3 2 0 0 2 2 2 0 Transglutaminase-like superfamily Glyco_hydro_76 PF03663.9 GAP93199.1 - 1e-139 466.0 11.8 5.2e-138 460.4 8.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 GAP93199.1 - 0.00012 21.2 4.7 0.048 12.7 0.2 3.1 2 1 0 3 3 3 3 Glycosyl Hydrolase Family 88 NAP PF00956.13 GAP93200.1 - 8e-49 165.9 3.0 8e-49 165.9 2.1 1.7 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Cwf_Cwc_15 PF04889.7 GAP93200.1 - 0.0016 18.1 5.2 0.0016 18.1 3.6 2.2 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Nucleo_P87 PF07267.6 GAP93200.1 - 0.0063 15.2 1.5 0.0063 15.2 1.0 1.6 2 0 0 2 2 2 1 Nucleopolyhedrovirus capsid protein P87 Drc1-Sld2 PF11719.3 GAP93200.1 - 0.39 9.7 7.5 0.62 9.0 5.2 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein CENP-B_dimeris PF09026.5 GAP93200.1 - 2.8 8.2 28.4 3.8 7.7 8.6 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Tim17 PF02466.14 GAP93201.1 - 4.2e-47 159.3 7.6 4.9e-47 159.1 5.2 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Glyco_hydro_16 PF00722.16 GAP93202.1 - 7.6e-12 44.8 0.0 1.4e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 LPAM_2 PF13627.1 GAP93202.1 - 0.13 11.9 0.2 0.39 10.4 0.1 1.8 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site LRR19-TM PF15176.1 GAP93202.1 - 0.17 11.5 0.3 0.34 10.6 0.2 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain SCO1-SenC PF02630.9 GAP93203.1 - 2.3e-60 203.1 0.0 3e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 GAP93203.1 - 7.1e-07 28.9 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 GAP93203.1 - 0.0012 18.9 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 GAP93203.1 - 0.068 12.7 0.0 1 8.8 0.0 2.1 1 1 0 1 1 1 0 Redoxin Hydrolase_6 PF13344.1 GAP93204.1 - 1.3e-22 79.5 0.0 2.3e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAP93204.1 - 1.5e-15 56.6 0.1 1e-14 53.9 0.0 2.4 3 0 0 3 3 3 1 HAD-hyrolase-like HAD_2 PF13419.1 GAP93204.1 - 5.2e-05 23.5 0.0 0.0078 16.4 0.0 3.4 4 1 1 5 5 5 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAP93204.1 - 0.00054 20.4 0.0 0.17 12.2 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Choline_kinase PF01633.15 GAP93205.1 - 3.5e-61 206.4 0.0 7.5e-61 205.3 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 GAP93205.1 - 2.8e-20 71.5 0.0 5.6e-20 70.5 0.0 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 GAP93205.1 - 1.1e-08 35.1 0.3 4.1e-07 29.9 0.0 3.0 3 1 0 3 3 3 1 Phosphotransferase enzyme family DASH_Dad2 PF08654.5 GAP93205.1 - 0.08 12.9 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 DASH complex subunit Dad2 zf-C2H2 PF00096.21 GAP93208.1 - 5.2e-09 35.9 12.3 0.00033 20.8 1.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAP93208.1 - 1.7e-07 31.2 8.9 8.7e-07 28.9 0.8 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAP93208.1 - 0.00022 21.3 13.8 0.008 16.4 1.2 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 GAP93208.1 - 0.0072 16.4 3.4 0.033 14.4 1.0 3.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 GAP93208.1 - 0.057 13.5 0.7 0.057 13.5 0.5 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 GAP93208.1 - 0.31 11.0 2.3 8.1 6.4 0.3 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-BED PF02892.10 GAP93208.1 - 3.4 7.4 8.9 11 5.8 0.9 2.5 1 1 1 2 2 2 0 BED zinc finger Lipase_GDSL_2 PF13472.1 GAP93209.1 - 7.3e-08 32.7 0.3 2.4e-07 31.0 0.1 2.0 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAP93209.1 - 1.3e-07 31.6 4.9 3.8e-06 26.9 1.2 2.5 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase DUF2365 PF10157.4 GAP93210.1 - 0.004 17.0 0.5 0.0053 16.6 0.3 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) YscO PF07321.7 GAP93210.1 - 0.013 15.3 1.0 0.013 15.3 0.7 2.2 1 1 1 2 2 2 0 Type III secretion protein YscO HSBP1 PF06825.7 GAP93210.1 - 0.019 14.4 0.4 2.8 7.5 0.1 2.5 2 1 0 2 2 2 0 Heat shock factor binding protein 1 PLU-1 PF08429.6 GAP93210.1 - 0.061 12.2 0.8 0.078 11.8 0.5 1.2 1 0 0 1 1 1 0 PLU-1-like protein BAR_2 PF10455.4 GAP93210.1 - 0.064 12.1 1.0 0.082 11.8 0.7 1.2 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking CMD PF02627.15 GAP93210.1 - 0.095 12.5 0.1 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family Zip PF02535.17 GAP93210.1 - 0.17 10.8 2.7 0.15 11.0 1.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter BBP1_C PF15272.1 GAP93210.1 - 0.19 11.2 4.4 0.31 10.5 3.0 1.5 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal DUF3450 PF11932.3 GAP93210.1 - 0.46 9.7 5.3 0.24 10.6 1.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) UreE_C PF05194.7 GAP93210.1 - 0.72 9.9 14.5 0.8 9.8 8.8 2.1 2 1 0 2 2 2 0 UreE urease accessory protein, C-terminal domain PHD PF00628.24 GAP93211.1 - 6.3e-09 35.3 2.2 6.3e-09 35.3 1.5 2.3 2 0 0 2 2 2 1 PHD-finger zf-tcix PF14952.1 GAP93211.1 - 0.22 10.8 2.7 0.4 10.0 0.0 2.3 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Carla_C4 PF01623.12 GAP93211.1 - 1.4 8.7 5.4 1.6 8.5 1.3 2.2 2 0 0 2 2 2 0 Carlavirus putative nucleic acid binding protein DivIC PF04977.10 GAP93212.1 - 0.13 11.7 9.3 0.36 10.3 1.5 3.5 4 0 0 4 4 4 0 Septum formation initiator DUF2680 PF10925.3 GAP93212.1 - 1.5 8.7 8.1 1.6 8.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2680) Med9 PF07544.8 GAP93212.1 - 3.5 7.4 7.2 3.8 7.3 0.5 3.2 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 AAA PF00004.24 GAP93213.1 - 5.5e-17 62.2 0.0 1.2e-16 61.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAP93213.1 - 0.00096 19.1 0.0 0.0023 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.1 GAP93213.1 - 0.0033 17.0 0.1 0.011 15.3 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAP93213.1 - 0.0056 16.8 0.1 0.032 14.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 GAP93213.1 - 0.0064 16.2 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 GAP93213.1 - 0.0071 16.2 0.0 0.033 14.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAP93213.1 - 0.008 16.9 0.3 0.033 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 GAP93213.1 - 0.011 15.1 0.1 0.022 14.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAP93213.1 - 0.017 15.4 1.4 0.079 13.2 0.0 3.0 3 1 1 4 4 4 0 AAA domain IstB_IS21 PF01695.12 GAP93213.1 - 0.03 13.7 0.0 0.065 12.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 GAP93213.1 - 0.034 14.3 0.6 0.11 12.6 0.0 2.3 3 0 0 3 3 2 0 RNA helicase RuvB_N PF05496.7 GAP93213.1 - 0.11 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ArgK PF03308.11 GAP93213.1 - 0.19 10.4 0.1 0.31 9.7 0.1 1.3 1 0 0 1 1 1 0 ArgK protein DUF619 PF04768.8 GAP93214.1 - 0.077 12.4 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF619) FA_desaturase PF00487.19 GAP93215.1 - 4.4e-09 36.1 30.5 4.4e-09 36.1 21.1 1.7 1 1 1 2 2 2 1 Fatty acid desaturase zf-CCHC PF00098.18 GAP93216.1 - 1.4e-11 43.6 9.7 1.8e-05 24.4 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 GAP93216.1 - 8.6e-09 34.9 0.2 1.6e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 GAP93216.1 - 1.4e-06 27.9 6.5 0.0012 18.5 2.3 2.6 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 GAP93216.1 - 1.4e-05 24.5 0.2 3.3e-05 23.4 0.2 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_6 PF15288.1 GAP93216.1 - 0.00061 19.4 8.3 0.073 12.7 0.4 2.7 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 GAP93216.1 - 0.0011 18.5 6.0 0.29 10.8 0.5 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 GAP93216.1 - 0.06 12.8 0.2 0.06 12.8 0.1 3.3 2 1 1 3 3 3 0 Zinc knuckle Peptidase_M16_C PF05193.16 GAP93216.1 - 0.7 9.5 3.3 7.7 6.1 0.0 2.9 3 0 0 3 3 3 0 Peptidase M16 inactive domain TPR_2 PF07719.12 GAP93217.1 - 1.8e-28 96.1 23.2 0.00019 21.0 0.3 10.2 10 0 0 10 10 9 8 Tetratricopeptide repeat Apc3 PF12895.2 GAP93217.1 - 7e-28 96.5 19.4 3.5e-22 78.3 0.4 5.6 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 GAP93217.1 - 2.4e-27 94.3 21.3 3.2e-09 36.3 0.2 7.5 6 1 1 7 7 7 6 TPR repeat TPR_1 PF00515.23 GAP93217.1 - 2.1e-26 90.3 15.0 3.2e-05 23.3 0.6 9.9 9 1 0 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.1 GAP93217.1 - 2.7e-23 82.1 15.0 0.00025 21.2 0.3 7.8 5 3 2 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.1 GAP93217.1 - 1.1e-20 73.2 20.7 8.5e-10 38.4 0.8 8.5 6 2 1 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 GAP93217.1 - 1.7e-19 69.9 20.8 5e-09 36.5 1.3 7.4 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAP93217.1 - 8.4e-19 66.3 21.9 0.0017 18.8 0.8 9.2 5 3 4 9 9 9 4 Tetratricopeptide repeat TPR_10 PF13374.1 GAP93217.1 - 7.1e-15 54.3 7.2 0.00093 19.0 0.1 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAP93217.1 - 1.9e-14 52.2 6.0 0.0064 16.1 0.2 8.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 GAP93217.1 - 3.4e-11 42.8 12.2 0.55 10.8 0.1 8.3 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAP93217.1 - 1.9e-10 39.7 21.1 0.28 11.0 0.2 8.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_15 PF13429.1 GAP93217.1 - 8.7e-05 21.7 8.8 0.11 11.5 0.6 4.3 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAP93217.1 - 0.00019 21.3 12.8 2 8.7 0.1 7.9 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAP93217.1 - 0.00028 20.6 16.6 0.052 13.4 0.7 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat PPR PF01535.15 GAP93217.1 - 0.0014 18.4 0.1 1.6 8.8 0.0 4.6 4 0 0 4 4 4 1 PPR repeat Coatomer_E PF04733.9 GAP93217.1 - 0.0019 17.4 0.2 15 4.6 0.0 3.7 3 1 1 4 4 4 0 Coatomer epsilon subunit TPR_20 PF14561.1 GAP93217.1 - 0.0036 17.3 6.9 0.11 12.6 0.7 4.6 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_21 PF09976.4 GAP93217.1 - 0.02 14.8 12.5 4.5 7.2 0.8 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 GAP93217.1 - 0.04 14.3 13.0 1.3 9.6 0.0 6.7 8 0 0 8 8 7 0 Tetratricopeptide repeat Pet191_N PF10203.4 GAP93217.1 - 0.15 12.1 0.8 0.61 10.1 0.5 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Fis1_TPR_C PF14853.1 GAP93217.1 - 0.29 11.0 9.8 17 5.3 0.1 5.6 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 GAP93217.1 - 0.3 11.0 2.3 56 3.7 0.0 4.2 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Rep_fac_C PF08542.6 GAP93218.1 - 3.8e-19 68.4 0.0 7.4e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 GAP93218.1 - 2.3e-11 43.6 0.0 2.2e-09 37.1 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 GAP93218.1 - 3.8e-11 43.3 0.0 7.5e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 GAP93218.1 - 2.1e-07 30.9 0.0 4.5e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAP93218.1 - 2.3e-06 27.7 0.1 9.4e-05 22.4 0.0 2.7 1 1 2 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 GAP93218.1 - 1.2e-05 24.4 0.0 3.3e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 GAP93218.1 - 1.5e-05 25.1 0.2 0.03 14.4 0.0 2.8 2 1 1 3 3 2 2 AAA domain Rad17 PF03215.10 GAP93218.1 - 1.5e-05 23.8 0.0 0.023 13.4 0.0 2.9 2 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_3 PF07726.6 GAP93218.1 - 0.0001 21.9 0.0 0.00025 20.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 GAP93218.1 - 0.00013 21.6 0.0 0.0002 20.9 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 GAP93218.1 - 0.00052 19.5 0.0 0.062 12.7 0.0 2.2 1 1 1 2 2 2 1 AAA-like domain AAA_25 PF13481.1 GAP93218.1 - 0.0012 18.2 0.1 0.063 12.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAP93218.1 - 0.0017 18.0 0.0 0.0042 16.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 GAP93218.1 - 0.0035 16.5 0.0 0.022 13.8 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_31 PF13614.1 GAP93218.1 - 0.0055 16.6 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain DEAD PF00270.24 GAP93218.1 - 0.0064 15.9 0.1 0.22 10.9 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase ArgK PF03308.11 GAP93218.1 - 0.0067 15.2 0.0 0.014 14.1 0.0 1.6 1 0 0 1 1 1 1 ArgK protein NTPase_1 PF03266.10 GAP93218.1 - 0.0071 16.0 0.3 0.033 13.9 0.1 2.2 2 1 1 3 3 2 1 NTPase AAA_11 PF13086.1 GAP93218.1 - 0.016 14.8 0.0 0.029 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.5 GAP93218.1 - 0.016 14.4 0.0 0.032 13.4 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 FtsK_SpoIIIE PF01580.13 GAP93218.1 - 0.02 14.3 0.0 0.042 13.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.1 GAP93218.1 - 0.025 14.9 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.8 GAP93218.1 - 0.044 13.2 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit NB-ARC PF00931.17 GAP93218.1 - 0.1 11.4 0.0 0.19 10.5 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ArgJ PF01960.13 GAP93219.1 - 3.8e-140 466.7 3.7 4.3e-140 466.5 2.6 1.0 1 0 0 1 1 1 1 ArgJ family NUDIX PF00293.23 GAP93220.1 - 7.1e-07 28.9 0.2 4.7e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 NUDIX domain DER1 PF04511.10 GAP93221.1 - 9.3e-24 84.0 5.5 1.1e-23 83.8 3.8 1.0 1 0 0 1 1 1 1 Der1-like family DAO PF01266.19 GAP93224.1 - 2e-53 181.5 2.7 2.9e-53 181.0 1.8 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAP93224.1 - 6.6e-06 26.3 0.0 0.034 14.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAP93224.1 - 0.00012 21.1 4.0 0.00029 19.8 2.8 1.6 1 1 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 GAP93224.1 - 0.00028 20.0 0.6 0.00043 19.4 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 GAP93224.1 - 0.00038 20.4 0.0 0.00054 19.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAP93224.1 - 0.0004 19.5 0.2 0.00055 19.1 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAP93224.1 - 0.0026 16.2 0.6 0.14 10.6 0.4 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 GAP93224.1 - 0.0035 17.3 0.1 0.009 16.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAP93224.1 - 0.038 13.0 0.1 0.066 12.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 GAP93224.1 - 0.16 12.4 1.0 0.79 10.1 0.5 2.3 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAP93224.1 - 0.19 11.5 1.6 13 5.5 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 GAP93224.1 - 0.21 11.2 0.5 0.5 10.0 0.4 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 GAP93224.1 - 0.23 10.2 0.7 0.31 9.8 0.5 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A CN_hydrolase PF00795.17 GAP93225.1 - 3.7e-13 49.2 0.0 6e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DKCLD PF08068.7 GAP93227.1 - 1e-28 98.9 0.1 7.3e-28 96.2 0.0 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 GAP93227.1 - 2.6e-24 86.0 0.3 1.8e-21 76.8 0.2 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 GAP93227.1 - 1e-20 73.1 1.1 2.1e-20 72.2 0.8 1.5 1 0 0 1 1 1 1 PUA domain SKG6 PF08693.5 GAP93228.1 - 0.0027 16.9 1.3 0.0057 15.9 0.9 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Phage_Coat_B PF05356.6 GAP93228.1 - 0.041 13.5 0.5 0.099 12.3 0.3 1.6 1 0 0 1 1 1 0 Phage Coat protein B Podoplanin PF05808.6 GAP93228.1 - 0.053 13.0 0.3 0.053 13.0 0.2 1.9 2 0 0 2 2 2 0 Podoplanin Adeno_E3_CR2 PF02439.10 GAP93228.1 - 0.099 12.2 0.7 0.19 11.3 0.5 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Tyrosinase PF00264.15 GAP93229.1 - 2.5e-51 174.9 0.5 4.9e-51 174.0 0.3 1.5 1 1 0 1 1 1 1 Common central domain of tyrosinase DUF1996 PF09362.5 GAP93230.1 - 8.1e-85 284.2 3.7 1.1e-84 283.8 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) NmrA PF05368.8 GAP93231.1 - 1.8e-27 96.1 0.1 2.3e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAP93231.1 - 7.1e-17 62.0 0.1 1.4e-16 60.9 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 GAP93231.1 - 0.0076 16.6 0.1 0.023 15.0 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 GAP93231.1 - 0.0076 16.0 0.0 0.04 13.7 0.0 2.2 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.16 GAP93231.1 - 0.013 14.9 0.1 0.21 10.9 0.0 2.5 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAP93231.1 - 0.024 13.3 0.0 0.08 11.6 0.0 1.8 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family B12-binding PF02310.14 GAP93231.1 - 0.026 14.3 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain Pou PF00157.12 GAP93231.1 - 0.061 12.9 0.3 0.24 11.0 0.1 2.1 2 0 0 2 2 2 0 Pou domain - N-terminal to homeobox domain NAD_binding_4 PF07993.7 GAP93231.1 - 0.079 11.8 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein DUF4319 PF14203.1 GAP93231.1 - 0.51 9.9 3.6 0.63 9.6 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4319) adh_short PF00106.20 GAP93232.1 - 4.1e-25 88.6 0.1 5.2e-25 88.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAP93232.1 - 2.1e-12 47.3 0.0 2.8e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAP93232.1 - 1.4e-09 37.9 0.1 2.8e-09 36.9 0.1 1.4 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 GAP93232.1 - 0.0066 16.2 0.1 0.013 15.2 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 GAP93232.1 - 0.016 14.6 0.1 0.055 12.9 0.0 1.9 2 1 1 3 3 3 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 GAP93232.1 - 0.11 11.5 0.1 0.27 10.2 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Nuc_sug_transp PF04142.10 GAP93234.1 - 8.4e-09 34.8 0.3 1.3e-08 34.3 0.2 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 GAP93234.1 - 4.2e-05 22.6 8.7 6.5e-05 21.9 6.1 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 GAP93234.1 - 9.5e-05 22.4 28.6 0.018 15.0 6.9 3.4 2 1 1 3 3 3 3 EamA-like transporter family TPT PF03151.11 GAP93234.1 - 0.00043 19.9 13.5 0.096 12.3 0.5 2.7 2 1 0 2 2 2 2 Triose-phosphate Transporter family PDR_assoc PF08370.6 GAP93234.1 - 0.00094 18.6 3.4 6.2 6.4 0.0 3.7 3 0 0 3 3 3 3 Plant PDR ABC transporter associated Yippee-Mis18 PF03226.9 GAP93235.1 - 4.2e-23 81.1 0.7 4.7e-23 81.0 0.5 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.1 GAP93235.1 - 0.0024 17.8 0.6 0.057 13.4 0.0 2.2 2 0 0 2 2 2 1 HNH endonuclease RIG-I_C-RD PF11648.3 GAP93235.1 - 0.023 14.5 1.3 0.065 13.1 0.9 1.7 1 1 0 1 1 1 0 C-terminal domain of RIG-I GFA PF04828.9 GAP93235.1 - 0.025 14.5 1.4 0.98 9.4 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF2039 PF10217.4 GAP93235.1 - 0.043 13.8 0.7 0.13 12.3 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) NAD_binding_6 PF08030.7 GAP93236.1 - 2.6e-19 69.6 0.0 4.1e-11 43.0 0.0 2.5 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 GAP93236.1 - 7.4e-19 68.0 8.8 7.4e-19 68.0 6.1 2.6 4 0 0 4 4 4 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 GAP93236.1 - 2.6e-17 62.6 0.0 1.1e-16 60.6 0.0 2.0 1 1 0 1 1 1 1 FAD-binding domain CLU PF13236.1 GAP93238.1 - 1.2e-78 263.5 0.0 1.8e-78 262.9 0.0 1.3 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 GAP93238.1 - 1.4e-46 158.5 0.0 3.5e-46 157.2 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 GAP93238.1 - 1.2e-23 83.0 0.1 3.1e-23 81.7 0.0 1.8 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 GAP93238.1 - 2e-20 72.4 13.8 1e-09 38.1 1.2 3.4 2 1 1 4 4 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 GAP93238.1 - 3.1e-19 68.2 0.2 2.1e-05 24.2 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 GAP93238.1 - 4.9e-07 29.2 5.1 0.0025 17.4 0.0 3.5 3 1 1 4 4 3 3 TPR repeat TPR_2 PF07719.12 GAP93238.1 - 0.0015 18.3 8.5 0.054 13.4 0.1 4.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAP93238.1 - 0.0017 17.8 2.1 0.074 12.6 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 GAP93238.1 - 0.0033 17.2 0.3 0.11 12.3 0.0 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat DUF727 PF05303.7 GAP93238.1 - 0.009 15.7 0.0 0.029 14.1 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_7 PF13176.1 GAP93238.1 - 0.021 14.6 1.6 3.3 7.7 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAP93238.1 - 0.023 15.3 4.6 4.1 8.1 0.0 3.6 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAP93238.1 - 0.11 13.2 7.5 0.52 11.0 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAP93238.1 - 0.29 11.0 1.8 3.7 7.5 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Fork_head PF00250.13 GAP93239.1 - 3.3e-32 110.3 0.1 6.2e-32 109.5 0.1 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 GAP93239.1 - 2.4e-06 27.5 0.0 4.5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain STE PF02200.11 GAP93241.1 - 6.2e-62 206.5 0.5 1.5e-61 205.3 0.1 1.8 2 0 0 2 2 2 1 STE like transcription factor zf-C2H2 PF00096.21 GAP93241.1 - 3.5e-11 42.7 12.0 2.6e-06 27.4 1.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAP93241.1 - 1.2e-09 37.7 11.0 6.6e-05 22.9 1.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAP93241.1 - 3.8e-08 33.2 4.6 3.8e-08 33.2 3.2 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 GAP93241.1 - 0.00017 21.3 1.5 0.00026 20.7 0.2 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAP93241.1 - 0.0025 17.9 1.3 0.033 14.3 0.2 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-RING_3 PF14369.1 GAP93241.1 - 0.0094 15.9 0.2 0.024 14.6 0.2 1.7 1 0 0 1 1 1 1 zinc-finger zf-Di19 PF05605.7 GAP93241.1 - 0.48 10.5 3.1 0.91 9.7 2.2 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 GAP93241.1 - 5.4 7.3 6.1 3.4 7.9 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type AhpC-TSA_2 PF13911.1 GAP93242.1 - 1.5e-10 41.0 0.0 2.1e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 GAP93242.1 - 8.1e-06 25.5 0.0 1.3e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 GAP93242.1 - 0.0028 17.1 0.0 0.059 12.9 0.0 2.0 2 0 0 2 2 2 1 Redoxin Thioredoxin_8 PF13905.1 GAP93242.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like Tubulin_3 PF14881.1 GAP93243.1 - 3.5e-77 257.9 1.5 9.9e-76 253.2 0.6 2.5 2 1 0 2 2 2 1 Tubulin domain Misat_Tub_SegII PF10644.4 GAP93243.1 - 2.9e-42 143.3 0.0 6.5e-42 142.2 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 GAP93243.1 - 4.1e-07 30.0 0.0 0.0028 17.5 0.0 2.2 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Glyco_hydro_35 PF01301.14 GAP93244.1 - 4.7e-83 279.1 0.1 6.6e-83 278.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 GAP93244.1 - 3e-45 153.0 3.3 1.2e-21 77.0 0.3 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 GAP93244.1 - 1.7e-35 122.0 0.3 1.1e-33 116.0 0.2 2.3 1 1 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 GAP93244.1 - 2.7e-16 58.7 0.2 1.2e-15 56.5 0.0 2.2 3 0 0 3 3 3 1 Beta-galactosidase, domain 3 Chorismate_bind PF00425.13 GAP93245.1 - 3e-24 85.7 0.0 1.2e-19 70.7 0.0 2.4 2 0 0 2 2 2 2 chorismate binding enzyme GATase PF00117.23 GAP93245.1 - 5.7e-20 71.5 0.0 2.3e-19 69.5 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 GAP93245.1 - 1.5e-16 60.6 0.0 3.2e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 GAP93245.1 - 0.00016 21.1 0.0 0.00031 20.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 DUF3397 PF11877.3 GAP93246.1 - 0.016 15.2 4.0 0.18 11.8 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3397) Metal_resist PF13801.1 GAP93246.1 - 0.2 11.6 0.2 0.2 11.6 0.1 2.4 2 1 1 3 3 3 0 Heavy-metal resistance Cytochrom_B_C PF00032.12 GAP93246.1 - 6.3 7.0 7.9 0.62 10.3 0.8 2.7 3 1 0 3 3 3 0 Cytochrome b(C-terminal)/b6/petD Yip1 PF04893.12 GAP93247.1 - 1e-12 47.8 18.0 1e-12 47.8 12.5 1.7 1 1 1 2 2 2 1 Yip1 domain DDDD PF10161.4 GAP93247.1 - 0.073 12.7 0.4 0.81 9.3 0.0 2.3 2 0 0 2 2 2 0 Putative mitochondrial precursor protein Kelch_5 PF13854.1 GAP93248.1 - 3.3e-14 52.4 8.6 5.9e-14 51.6 0.3 4.3 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 GAP93248.1 - 1.4e-07 31.1 1.8 0.15 11.8 0.1 4.8 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.1 GAP93248.1 - 5.7e-07 29.4 7.2 0.018 15.1 0.1 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 GAP93248.1 - 6.8e-07 29.2 10.9 0.0001 22.3 0.0 5.2 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.20 GAP93248.1 - 1.7e-05 24.2 2.3 0.22 11.0 0.0 4.0 3 0 0 3 3 3 2 Kelch motif ThiF PF00899.16 GAP93250.1 - 3.5e-51 172.6 0.0 4.1e-32 110.8 0.0 2.8 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 GAP93250.1 - 2.2e-37 126.4 3.6 2.7e-26 90.9 0.2 3.3 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 GAP93250.1 - 2.8e-36 124.4 0.0 7.9e-36 122.9 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 GAP93250.1 - 7.9e-24 82.7 0.5 1.4e-20 72.3 0.2 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site GST_N_2 PF13409.1 GAP93251.1 - 3.4e-20 71.8 0.0 6.8e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAP93251.1 - 2.1e-14 53.1 0.6 4.9e-14 51.9 0.2 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAP93251.1 - 4.8e-06 26.6 0.0 0.016 15.4 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAP93251.1 - 0.0015 18.5 0.0 0.0035 17.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAP93251.1 - 0.004 17.6 0.0 0.0085 16.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF663 PF04950.7 GAP93252.1 - 8.7e-83 277.7 0.0 8.7e-83 277.7 0.0 2.0 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 GAP93252.1 - 6.2e-26 89.7 0.0 1.5e-25 88.5 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.1 GAP93252.1 - 3.1e-06 27.3 0.0 8.7e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAP93252.1 - 1.8e-05 24.8 0.3 8.5e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.22 GAP93252.1 - 2.5e-05 23.7 0.0 0.0066 15.8 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 GAP93252.1 - 7.3e-05 22.6 1.4 0.00053 19.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 GAP93252.1 - 0.00012 22.2 0.1 0.00028 21.1 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 GAP93252.1 - 0.0003 21.6 0.0 0.0003 21.6 0.0 4.5 3 1 0 3 3 1 1 AAA domain Miro PF08477.8 GAP93252.1 - 0.00043 20.7 0.0 0.0016 18.9 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 GAP93252.1 - 0.00072 19.5 0.1 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 GAP93252.1 - 0.00079 19.1 0.1 0.0023 17.6 0.1 1.9 1 1 0 1 1 1 1 NACHT domain ABC_tran PF00005.22 GAP93252.1 - 0.0011 19.2 0.3 0.0042 17.3 0.0 2.1 2 0 0 2 2 1 1 ABC transporter AAA_18 PF13238.1 GAP93252.1 - 0.0018 18.5 0.1 0.0018 18.5 0.1 4.3 4 2 0 4 4 4 1 AAA domain AAA_25 PF13481.1 GAP93252.1 - 0.0041 16.5 0.0 0.014 14.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 GAP93252.1 - 0.0045 16.7 0.2 0.0099 15.5 0.1 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 GAP93252.1 - 0.0047 16.8 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAP93252.1 - 0.008 15.9 1.0 0.017 14.8 0.1 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_24 PF13479.1 GAP93252.1 - 0.0094 15.5 0.2 0.023 14.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 GAP93252.1 - 0.015 14.1 0.0 0.032 13.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_10 PF12846.2 GAP93252.1 - 0.018 14.4 0.0 0.037 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain NTPase_1 PF03266.10 GAP93252.1 - 0.026 14.2 0.4 0.048 13.3 0.3 1.4 1 0 0 1 1 1 0 NTPase cobW PF02492.14 GAP93252.1 - 0.027 13.9 0.1 0.053 12.9 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 GAP93252.1 - 0.027 13.6 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 GAP93252.1 - 0.031 14.4 0.0 0.085 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 GAP93252.1 - 0.048 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 GAP93252.1 - 0.077 12.4 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.10 GAP93252.1 - 0.17 10.5 0.0 0.39 9.3 0.0 1.5 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein ATP_bind_1 PF03029.12 GAP93252.1 - 0.23 10.9 0.1 0.6 9.6 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_11 PF13086.1 GAP93252.1 - 1.6 8.2 5.6 2.5 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Inhibitor_I9 PF05922.11 GAP93253.1 - 7.1e-15 55.3 0.1 7.9e-15 55.2 0.1 1.0 1 0 0 1 1 1 1 Peptidase inhibitor I9 BCDHK_Adom3 PF10436.4 GAP93254.1 - 1.5e-41 141.6 0.0 2e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 GAP93254.1 - 2.6e-17 62.5 0.0 1.1e-15 57.3 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 GAP93254.1 - 0.0065 16.2 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.1 GAP93254.1 - 0.048 13.3 0.0 0.13 11.9 0.0 1.7 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Chitin_synth_2 PF03142.10 GAP93255.1 - 1.7e-228 759.3 0.0 2.4e-228 758.8 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 GAP93255.1 - 4.1e-61 206.9 0.0 1.5e-60 205.0 0.0 1.8 1 1 0 1 1 1 1 Myosin head (motor domain) Glyco_trans_2_3 PF13632.1 GAP93255.1 - 3.7e-17 62.6 2.9 3.7e-17 62.6 2.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAP93255.1 - 1.8e-15 57.3 0.0 8.4e-13 48.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 DEK_C PF08766.6 GAP93255.1 - 4.3e-14 52.0 3.5 3.9e-13 48.9 2.0 2.3 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.23 GAP93255.1 - 1.2e-13 50.5 0.0 8.6e-10 38.2 0.0 2.6 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 GAP93255.1 - 1.7e-07 30.6 0.0 4.7e-06 25.9 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 GAP93255.1 - 0.00048 19.8 0.0 0.03 13.9 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Chitin_synth_2 PF03142.10 GAP93256.1 - 3.3e-255 847.4 0.5 5.4e-255 846.7 0.3 1.4 2 0 0 2 2 2 1 Chitin synthase Myosin_head PF00063.16 GAP93256.1 - 4.5e-170 567.0 0.0 6e-170 566.6 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.6 GAP93256.1 - 6.4e-18 64.2 0.6 2.1e-17 62.6 0.3 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 GAP93256.1 - 7e-17 61.9 0.1 2.6e-13 50.2 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 GAP93256.1 - 2.3e-16 60.0 4.9 2.3e-16 60.0 3.4 2.4 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.23 GAP93256.1 - 3.8e-16 58.6 0.0 4.2e-10 39.2 0.0 3.0 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 GAP93256.1 - 2.5e-06 27.2 0.0 0.00034 20.3 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 AAA_16 PF13191.1 GAP93256.1 - 0.00074 19.5 0.3 0.0037 17.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Glyco_transf_21 PF13506.1 GAP93256.1 - 0.001 18.3 0.0 0.0034 16.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 21 AAA_29 PF13555.1 GAP93256.1 - 0.0094 15.4 0.2 0.05 13.1 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 GAP93256.1 - 0.014 15.5 0.5 0.053 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.5 GAP93256.1 - 0.055 12.6 0.5 0.26 10.4 0.3 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_23 PF13476.1 GAP93256.1 - 0.064 13.5 0.1 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 GAP93256.1 - 0.069 11.7 0.0 0.12 10.9 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Gtr1_RagA PF04670.7 GAP93256.1 - 0.085 11.9 0.1 0.19 10.8 0.1 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_25 PF13481.1 GAP93256.1 - 0.1 11.9 0.0 0.27 10.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 GAP93256.1 - 0.14 11.9 0.1 0.54 9.9 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.15 GAP93256.1 - 0.2 10.2 0.1 0.91 8.1 0.1 1.9 2 0 0 2 2 2 0 G-protein alpha subunit Na_Ca_ex PF01699.19 GAP93257.1 - 1.8e-23 82.6 19.4 4e-15 55.6 1.5 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein GPI-anchored PF10342.4 GAP93258.1 - 0.00048 20.5 0.0 0.00076 19.9 0.0 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family F-box-like PF12937.2 GAP93259.1 - 0.00015 21.4 0.1 0.00034 20.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAP93259.1 - 0.0048 16.5 0.1 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 F-box domain TT_ORF2 PF02957.10 GAP93259.1 - 0.92 10.2 4.2 0.39 11.4 0.1 2.1 2 0 0 2 2 2 0 TT viral ORF2 Cupin_2 PF07883.6 GAP93260.1 - 7.6e-08 31.7 0.0 1.4e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 GAP93260.1 - 0.0013 18.4 0.2 0.002 17.7 0.1 1.3 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 GAP93260.1 - 0.068 12.5 0.3 0.15 11.4 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF861) Amidase PF01425.16 GAP93261.1 - 2.7e-25 89.1 0.6 1.1e-23 83.8 0.7 2.1 2 0 0 2 2 2 2 Amidase CoA_transf_3 PF02515.12 GAP93263.1 - 1.6e-27 96.0 0.0 5.3e-25 87.7 0.0 2.4 2 0 0 2 2 2 2 CoA-transferase family III Glyco_hydro_12 PF01670.11 GAP93264.1 - 1.2e-24 86.8 0.8 1.2e-24 86.8 0.5 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 12 GFO_IDH_MocA PF01408.17 GAP93265.1 - 2.4e-13 50.6 0.0 4.8e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 GAP93265.1 - 4.4e-05 23.2 0.1 0.00014 21.6 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GST_N_3 PF13417.1 GAP93266.1 - 6.7e-14 51.8 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAP93266.1 - 2.4e-12 46.8 0.0 4.9e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAP93266.1 - 3.1e-12 46.2 0.0 7.4e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAP93266.1 - 2.7e-07 30.4 0.0 4.9e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAP93266.1 - 0.0031 17.9 0.0 0.0051 17.2 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAP93266.1 - 0.026 14.4 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MutL_C PF08676.6 GAP93267.1 - 1.4e-21 76.5 0.2 6e-21 74.5 0.1 2.1 1 1 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 GAP93267.1 - 1.8e-18 66.1 0.0 4.4e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 GAP93267.1 - 1.5e-14 53.8 0.7 7.4e-13 48.3 0.0 2.8 2 1 1 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 GAP93267.1 - 3.7e-11 42.7 0.0 7.6e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PGAP1 PF07819.8 GAP93268.1 - 7.5e-88 293.8 0.0 1.1e-87 293.3 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 GAP93268.1 - 4.9e-07 29.6 0.0 9.2e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAP93268.1 - 0.00019 21.3 0.0 0.0004 20.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP93268.1 - 0.0051 16.3 0.0 0.0099 15.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 GAP93268.1 - 0.053 12.7 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2974 PF11187.3 GAP93268.1 - 0.17 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) MFS_1 PF07690.11 GAP93269.1 - 2.1e-15 56.3 46.1 5.1e-15 55.0 11.5 3.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 GAP93269.1 - 3.2e-10 39.6 2.5 3.2e-10 39.6 1.7 1.8 2 0 0 2 2 2 1 Nodulin-like Serinc PF03348.10 GAP93270.1 - 6.6e-174 578.6 6.9 7.6e-174 578.4 4.8 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) FlgM PF04316.8 GAP93270.1 - 0.036 13.9 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM DUF809 PF05663.6 GAP93270.1 - 0.099 12.5 0.4 0.28 11.1 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF809) Cys_Met_Meta_PP PF01053.15 GAP93271.1 - 1.9e-137 457.6 0.1 2.2e-137 457.4 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 GAP93271.1 - 1.1e-06 27.9 0.0 1.7e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 GAP93271.1 - 1.4e-05 23.9 0.0 5.7e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Met_gamma_lyase PF06838.6 GAP93271.1 - 2.9e-05 22.5 0.2 9e-05 20.9 0.1 1.6 1 1 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 GAP93271.1 - 0.00038 19.2 0.1 0.00059 18.6 0.1 1.3 1 0 0 1 1 1 1 Glycine cleavage system P-protein DegT_DnrJ_EryC1 PF01041.12 GAP93271.1 - 0.00085 18.4 0.1 0.0021 17.1 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 GAP93271.1 - 0.0065 15.6 0.2 0.024 13.8 0.1 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase POTRA_2 PF08479.6 GAP93271.1 - 0.1 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 POTRA domain, ShlB-type AAA PF00004.24 GAP93272.1 - 2.2e-38 131.4 0.0 4.3e-38 130.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAP93272.1 - 1.4e-06 28.4 0.1 0.00015 21.7 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 GAP93272.1 - 2e-06 27.7 0.0 4.3e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAP93272.1 - 8.4e-06 25.9 0.1 0.00023 21.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAP93272.1 - 1.4e-05 25.8 0.0 4.1e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 GAP93272.1 - 1.5e-05 24.1 0.0 2.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 GAP93272.1 - 4.8e-05 23.3 0.0 9.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 GAP93272.1 - 8e-05 22.3 0.1 0.00068 19.3 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 GAP93272.1 - 0.00033 20.5 0.0 0.00068 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 GAP93272.1 - 0.0005 19.2 0.0 0.00087 18.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 GAP93272.1 - 0.0011 18.1 0.1 0.0033 16.6 0.1 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 GAP93272.1 - 0.0026 17.8 0.0 0.007 16.5 0.0 1.8 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.12 GAP93272.1 - 0.0035 16.7 0.0 0.0068 15.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 GAP93272.1 - 0.0036 17.0 0.4 0.014 15.1 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 GAP93272.1 - 0.0037 16.6 0.2 0.14 11.5 0.1 2.6 1 1 0 2 2 2 1 AAA domain NACHT PF05729.7 GAP93272.1 - 0.0051 16.4 0.0 0.017 14.8 0.0 1.9 1 1 1 2 2 2 1 NACHT domain Sigma54_activ_2 PF14532.1 GAP93272.1 - 0.0054 16.7 0.0 0.022 14.8 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain NB-ARC PF00931.17 GAP93272.1 - 0.013 14.3 0.0 0.068 12.0 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activat PF00158.21 GAP93272.1 - 0.013 14.9 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 GAP93272.1 - 0.015 15.2 0.0 0.035 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAP93272.1 - 0.016 15.5 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 GAP93272.1 - 0.017 14.7 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 GAP93272.1 - 0.023 14.3 0.0 0.12 12.0 0.0 1.9 1 1 1 2 2 2 0 Archaeal ATPase DUF815 PF05673.8 GAP93272.1 - 0.031 13.2 0.0 0.06 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 GAP93272.1 - 0.032 14.5 0.0 0.061 13.6 0.0 1.8 1 1 0 1 1 1 0 ABC transporter TIP49 PF06068.8 GAP93272.1 - 0.034 12.8 0.0 0.063 11.9 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus Guanylate_kin PF00625.16 GAP93272.1 - 0.062 12.7 0.1 1.7 8.0 0.0 2.7 2 1 0 2 2 2 0 Guanylate kinase Oxidored_nitro PF00148.14 GAP93272.1 - 0.064 11.8 0.0 0.32 9.5 0.0 1.9 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase Viral_helicase1 PF01443.13 GAP93272.1 - 0.077 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 GAP93272.1 - 0.087 11.4 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_11 PF13086.1 GAP93272.1 - 0.088 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 GAP93272.1 - 0.088 12.4 0.0 0.23 11.0 0.0 1.7 1 1 0 1 1 1 0 Bacterial dnaA protein GMC_oxred_N PF00732.14 GAP93273.1 - 8e-55 186.0 0.0 1.1e-54 185.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAP93273.1 - 7.5e-32 110.5 0.1 1.9e-31 109.3 0.1 1.7 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAP93273.1 - 3.4e-06 26.1 0.0 0.014 14.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAP93273.1 - 1e-05 24.6 0.1 4.4e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAP93273.1 - 0.00017 21.5 0.1 0.00047 20.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAP93273.1 - 0.029 13.2 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 GAP93273.1 - 0.088 11.2 0.1 0.34 9.3 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_4 PF01565.18 GAP93275.1 - 5.1e-19 68.1 2.2 1.3e-18 66.8 1.5 1.7 1 1 0 1 1 1 1 FAD binding domain adh_short PF00106.20 GAP93276.1 - 0.0011 18.9 0.0 0.0038 17.1 0.0 1.9 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAP93276.1 - 0.003 17.2 0.0 0.0065 16.1 0.0 1.6 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAP93276.1 - 0.025 13.9 0.0 0.039 13.3 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAP93276.1 - 0.074 13.0 0.1 0.14 12.1 0.1 1.5 1 1 0 1 1 1 0 NADH(P)-binding NAD_binding_4 PF07993.7 GAP93276.1 - 0.13 11.1 0.0 0.27 10.1 0.0 1.5 2 0 0 2 2 2 0 Male sterility protein p450 PF00067.17 GAP93277.1 - 1.5e-11 43.5 0.0 1.9e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ammonium_transp PF00909.16 GAP93278.1 - 1.2e-117 392.8 28.5 1.4e-117 392.6 19.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family C2 PF00168.25 GAP93279.1 - 4.1e-18 65.0 0.1 6.3e-11 41.9 0.0 2.7 2 0 0 2 2 2 2 C2 domain Methyltransf_18 PF12847.2 GAP93280.1 - 7.8e-08 32.8 0.0 1.2e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP93280.1 - 5e-06 26.1 0.0 6.3e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP93280.1 - 8.1e-06 26.2 0.0 1.5e-05 25.3 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP93280.1 - 6.4e-05 23.3 0.0 0.00011 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP93280.1 - 0.00038 20.1 0.0 0.00084 19.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP93280.1 - 0.0035 17.6 0.0 0.0054 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP93280.1 - 0.012 15.5 0.9 0.018 15.0 0.1 1.6 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.13 GAP93280.1 - 0.15 11.1 0.0 0.2 10.7 0.0 1.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Adap_comp_sub PF00928.16 GAP93281.1 - 9.4e-86 287.1 0.0 1.2e-85 286.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 GAP93281.1 - 0.00014 21.5 0.1 0.00026 20.7 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1081 PF06448.6 GAP93281.1 - 0.033 14.0 0.1 0.075 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1081) Glyco_hydro_6 PF01341.12 GAP93282.1 - 4.7e-107 357.8 2.9 6.3e-107 357.4 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.13 GAP93282.1 - 3.2e-14 52.2 15.2 9.7e-14 50.7 10.5 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain ABC_tran PF00005.22 GAP93283.1 - 2.2e-46 157.5 0.0 4.3e-22 78.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 GAP93283.1 - 1.6e-19 70.9 0.2 0.00014 21.9 0.0 4.3 3 1 1 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 GAP93283.1 - 1.8e-19 69.3 5.7 1.8e-19 69.3 4.0 2.8 4 0 0 4 4 2 1 ABC transporter SMC_N PF02463.14 GAP93283.1 - 4.2e-13 49.0 0.2 5.3e-05 22.5 0.1 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 GAP93283.1 - 2.6e-09 37.6 4.0 0.033 14.5 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 GAP93283.1 - 4.9e-09 35.5 0.0 0.001 18.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.1 GAP93283.1 - 3.3e-07 30.6 1.4 0.026 14.8 0.0 3.1 4 0 0 4 4 2 2 AAA domain DUF258 PF03193.11 GAP93283.1 - 5e-07 29.0 0.0 0.00086 18.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 GAP93283.1 - 6.7e-07 30.1 0.1 0.0082 16.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAP93283.1 - 1.2e-06 28.6 0.0 0.046 13.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 GAP93283.1 - 3e-06 27.3 1.6 1.3 9.2 0.0 3.6 3 0 0 3 3 3 2 RNA helicase AAA_16 PF13191.1 GAP93283.1 - 3.4e-06 27.1 1.1 0.11 12.4 0.1 3.2 2 2 0 2 2 2 2 AAA ATPase domain Arch_ATPase PF01637.13 GAP93283.1 - 3.7e-06 26.8 0.6 0.079 12.6 0.0 3.3 3 0 0 3 3 3 1 Archaeal ATPase MMR_HSR1 PF01926.18 GAP93283.1 - 7.4e-06 25.9 0.0 0.063 13.2 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase NACHT PF05729.7 GAP93283.1 - 1e-05 25.2 0.1 0.13 11.9 0.0 2.8 2 0 0 2 2 2 2 NACHT domain AAA PF00004.24 GAP93283.1 - 1.3e-05 25.4 0.1 0.2 11.8 0.0 3.1 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAP93283.1 - 2.9e-05 23.8 0.2 0.14 11.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Miro PF08477.8 GAP93283.1 - 3.2e-05 24.3 0.0 0.052 14.0 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_28 PF13521.1 GAP93283.1 - 3.2e-05 23.9 0.0 0.024 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 GAP93283.1 - 3.5e-05 23.3 0.2 0.12 11.7 0.2 2.9 2 0 0 2 2 2 2 AAA-like domain AAA_15 PF13175.1 GAP93283.1 - 0.00023 20.3 0.0 0.12 11.3 0.0 3.2 4 1 0 4 4 3 1 AAA ATPase domain AAA_25 PF13481.1 GAP93283.1 - 0.00045 19.6 0.0 0.3 10.4 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 GAP93283.1 - 0.00049 19.9 0.0 1.5 8.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 GAP93283.1 - 0.0005 19.7 0.1 0.04 13.6 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 GAP93283.1 - 0.00083 19.2 0.1 0.41 10.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.17 GAP93283.1 - 0.0029 16.5 0.2 0.66 8.7 0.0 3.1 3 1 0 3 3 3 1 NB-ARC domain DUF2813 PF11398.3 GAP93283.1 - 0.0042 16.2 0.2 1.2 8.1 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2813) SbcCD_C PF13558.1 GAP93283.1 - 0.0078 16.1 1.4 0.64 9.9 0.1 3.8 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.10 GAP93283.1 - 0.008 15.9 0.2 2.7 7.6 0.1 2.8 2 0 0 2 2 2 1 NTPase Dynamin_N PF00350.18 GAP93283.1 - 0.0092 15.8 0.5 3.9 7.2 0.0 3.5 2 1 1 3 3 3 0 Dynamin family DUF87 PF01935.12 GAP93283.1 - 0.0092 15.8 0.1 4.1 7.1 0.0 2.8 3 0 0 3 3 2 0 Domain of unknown function DUF87 AAA_13 PF13166.1 GAP93283.1 - 0.017 13.6 0.5 6.5 5.0 0.0 3.3 3 1 0 3 3 3 0 AAA domain DAP3 PF10236.4 GAP93283.1 - 0.017 14.0 0.7 3.9 6.3 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_30 PF13604.1 GAP93283.1 - 0.02 14.4 0.1 4.9 6.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.8 GAP93283.1 - 0.028 13.3 0.0 2.7 6.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.4 GAP93283.1 - 0.036 13.5 1.1 4.7 6.6 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ABC_ATPase PF09818.4 GAP93283.1 - 0.062 11.8 0.0 15 3.9 0.0 3.2 3 1 0 3 3 3 0 Predicted ATPase of the ABC class FeoB_N PF02421.13 GAP93283.1 - 0.075 12.3 0.0 5.7 6.1 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B ArgK PF03308.11 GAP93283.1 - 0.09 11.5 3.6 7.9 5.1 0.1 3.1 3 0 0 3 3 3 0 ArgK protein ATP-synt_ab PF00006.20 GAP93283.1 - 0.12 11.8 0.1 1.4 8.3 0.0 2.4 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SNF2_N PF00176.18 GAP93284.1 - 6e-70 235.3 1.0 1.2e-69 234.3 0.7 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 GAP93284.1 - 4.2e-50 169.4 17.1 4.2e-50 169.4 11.8 4.5 3 1 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.26 GAP93284.1 - 2.2e-16 59.4 0.0 6.1e-16 58.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain YadA_stalk PF05662.9 GAP93286.1 - 0.59 9.9 8.3 3.1 7.7 0.8 3.1 3 0 0 3 3 3 0 Coiled stalk of trimeric autotransporter adhesin Hydrophobin PF01185.13 GAP93287.1 - 3.2e-15 56.3 7.1 3.9e-15 56.0 4.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Toxin_12 PF07740.7 GAP93287.1 - 3 8.4 10.8 3.9 8.0 1.0 3.0 3 0 0 3 3 3 0 Ion channel inhibitory toxin Lipase_3 PF01764.20 GAP93289.1 - 2.2e-12 46.8 0.0 4.4e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Dicty_CTDC PF00526.13 GAP93291.1 - 1.8 8.4 4.7 6 6.8 1.2 2.4 2 0 0 2 2 2 0 Dictyostelium (slime mold) repeat Piwi PF02171.12 GAP93292.1 - 4.9e-63 212.8 0.0 9.1e-63 212.0 0.0 1.4 1 1 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 GAP93292.1 - 3.1e-15 55.2 0.2 7.1e-15 54.1 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 GAP93292.1 - 4.1e-11 42.3 0.0 8.4e-11 41.3 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Vint PF14623.1 GAP93293.1 - 5.1e-43 146.3 0.0 9.5e-43 145.4 0.0 1.5 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.1 GAP93293.1 - 1.1e-25 89.5 0.0 1.9e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA_2 PF13519.1 GAP93293.1 - 5.8e-21 75.3 0.1 1.1e-20 74.4 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 GAP93293.1 - 2.5e-19 69.6 0.0 4.1e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 GAP93293.1 - 2.1e-09 37.2 0.2 5.6e-07 29.3 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain vWA-TerF-like PF10138.4 GAP93293.1 - 0.019 14.7 0.1 0.53 10.0 0.0 2.2 2 0 0 2 2 2 0 vWA found in TerF C terminus VWA_CoxE PF05762.9 GAP93293.1 - 0.17 11.0 0.0 1.4 7.9 0.0 2.0 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein PRKCSH-like PF12999.2 GAP93294.1 - 2.3e-39 134.7 12.1 5.6e-24 84.6 0.8 3.4 4 0 0 4 4 4 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 GAP93294.1 - 3.8e-31 107.6 0.5 3.8e-31 107.6 0.3 2.1 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 GAP93294.1 - 1.8e-11 44.6 3.5 6.5e-11 42.8 2.4 2.0 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein TolA PF06519.6 GAP93294.1 - 0.0013 18.6 0.0 0.0062 16.4 0.0 2.1 2 0 0 2 2 2 1 TolA C-terminal Prominin PF05478.6 GAP93294.1 - 0.1 10.0 2.1 0.17 9.3 1.4 1.3 1 0 0 1 1 1 0 Prominin DUF1470 PF07336.6 GAP93294.1 - 0.13 12.5 2.9 4 7.7 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1470) OmpH PF03938.9 GAP93294.1 - 0.15 11.9 9.3 4.7 7.1 4.6 2.5 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) NuA4 PF09340.5 GAP93294.1 - 0.28 10.8 7.1 2.2 7.9 0.3 2.6 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 Snapin_Pallidin PF14712.1 GAP93294.1 - 0.83 10.0 0.0 0.83 10.0 0.0 3.1 3 0 0 3 3 3 0 Snapin/Pallidin Fzo_mitofusin PF04799.8 GAP93294.1 - 2 7.7 8.5 19 4.6 1.3 3.1 3 0 0 3 3 3 0 fzo-like conserved region Fib_alpha PF08702.5 GAP93294.1 - 4.6 7.3 12.5 2.6 8.1 0.2 2.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Prefoldin_2 PF01920.15 GAP93294.1 - 4.7 7.0 17.0 0.83 9.4 3.7 3.6 3 0 0 3 3 3 0 Prefoldin subunit Rtf2 PF04641.7 GAP93295.1 - 3.6e-45 154.1 2.3 4.6e-45 153.8 1.6 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.1 GAP93295.1 - 0.0002 21.0 0.3 0.00096 18.9 0.0 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 GAP93295.1 - 0.00026 20.6 0.1 0.0037 16.9 0.0 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 GAP93295.1 - 0.0078 15.7 0.1 0.1 12.1 0.0 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.1 GAP93295.1 - 0.011 15.4 0.0 0.028 14.1 0.0 1.8 1 0 0 1 1 1 0 zinc-RING finger domain DiS_P_DiS PF06750.8 GAP93295.1 - 0.015 15.0 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain zf-C3HC4_3 PF13920.1 GAP93295.1 - 0.023 14.3 0.0 0.059 13.0 0.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAP93295.1 - 0.034 14.1 0.1 0.15 12.0 0.0 2.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) UPF0547 PF10571.4 GAP93295.1 - 8.3 6.1 7.4 12 5.7 0.1 2.8 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 FAT PF02259.18 GAP93296.1 - 3.9e-125 417.5 4.9 7.5e-125 416.5 3.4 1.5 1 0 0 1 1 1 1 FAT domain DUF3385 PF11865.3 GAP93296.1 - 9.8e-62 207.5 0.5 1e-59 201.0 0.2 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 GAP93296.1 - 1.1e-61 208.3 0.2 1.9e-61 207.5 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 GAP93296.1 - 5.9e-42 141.8 0.7 5.9e-42 141.8 0.5 2.6 2 0 0 2 2 2 1 Rapamycin binding domain HEAT PF02985.17 GAP93296.1 - 4.1e-15 54.4 9.7 0.025 14.6 0.0 11.2 10 0 0 10 10 10 2 HEAT repeat FATC PF02260.15 GAP93296.1 - 2.6e-14 52.3 0.2 5.9e-14 51.2 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.1 GAP93296.1 - 1e-13 51.3 11.2 0.0014 18.8 0.0 8.2 7 2 1 8 8 7 3 HEAT repeats HEAT_EZ PF13513.1 GAP93296.1 - 1.7e-12 47.4 12.3 0.00016 22.0 0.0 11.5 9 3 3 12 12 12 3 HEAT-like repeat Adaptin_N PF01602.15 GAP93296.1 - 9.6e-08 30.7 2.4 0.00062 18.2 0.0 4.7 3 1 0 4 4 4 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 GAP93296.1 - 4.5e-05 23.7 0.6 39 4.7 0.0 6.7 6 1 1 7 7 7 0 Vacuolar 14 Fab1-binding region Apc3 PF12895.2 GAP93296.1 - 0.12 12.5 3.3 9.5 6.4 0.1 3.6 3 1 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Pex24p PF06398.6 GAP93299.1 - 4.2e-95 318.6 0.0 4.9e-95 318.3 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Sugar_tr PF00083.19 GAP93300.1 - 1e-08 34.2 0.7 1.1e-08 34.0 0.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.19 GAP93301.1 - 1.8e-74 250.9 16.6 2e-74 250.7 11.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAP93301.1 - 1.2e-22 80.1 29.0 2e-22 79.4 20.1 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 GAP93302.1 - 1.2e-23 83.4 41.5 2.6e-18 65.8 7.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP93302.1 - 9.7e-09 34.3 0.7 9.7e-09 34.3 0.5 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 GAP93302.1 - 0.0076 14.4 0.3 0.015 13.5 0.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 GAP93302.1 - 0.013 15.3 0.3 0.057 13.2 0.0 2.3 2 0 0 2 2 2 0 MFS_1 like family MFS_3 PF05977.8 GAP93302.1 - 0.72 7.8 17.4 2.3 6.2 0.6 3.1 2 1 1 3 3 3 0 Transmembrane secretion effector Glyco_hydro_71 PF03659.9 GAP93303.1 - 1.5e-115 385.7 0.8 1.9e-115 385.4 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 GCIP PF13324.1 GAP93304.1 - 6.2e-06 25.6 0.9 8.5e-06 25.1 0.1 1.5 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting BTB PF00651.26 GAP93305.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Pribosyl_synth PF14572.1 GAP93306.1 - 1.1e-41 142.6 2.8 8.3e-36 123.4 0.9 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 GAP93306.1 - 8.5e-32 109.3 0.0 4.4e-31 107.0 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 GAP93306.1 - 5.2e-12 45.5 0.2 1.2e-11 44.4 0.2 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PEX11 PF05648.9 GAP93307.1 - 2.9e-65 219.6 0.1 3.4e-65 219.4 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Spherulin4 PF12138.3 GAP93308.1 - 2.5e-38 131.9 0.0 3.1e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Spherulation-specific family 4 Ras PF00071.17 GAP93309.1 - 4.5e-54 182.2 0.0 5.1e-54 182.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAP93309.1 - 7.8e-18 65.1 0.0 1.1e-17 64.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAP93309.1 - 2e-06 27.1 0.0 2.7e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RRM_1 PF00076.17 GAP93310.1 - 8.7e-12 44.5 0.0 2.4e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAP93310.1 - 7.3e-11 41.8 0.0 1.6e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Mucin PF01456.12 GAP93310.1 - 9.1 6.0 18.8 1.3 8.7 8.0 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein CMS1 PF14617.1 GAP93311.1 - 6.4e-78 261.2 0.0 7.5e-78 261.0 0.0 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 GAP93311.1 - 1.9e-05 24.2 0.0 2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Cu-oxidase_3 PF07732.10 GAP93313.1 - 3.7e-27 94.4 0.0 7.3e-27 93.4 0.0 1.5 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.17 GAP93313.1 - 4.9e-27 94.7 0.1 2.9e-26 92.2 0.0 2.2 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 GAP93313.1 - 3.6e-06 26.5 3.2 0.048 13.1 0.3 3.1 2 2 0 2 2 2 2 Multicopper oxidase DUF1249 PF06853.7 GAP93313.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1249) CorA PF01544.13 GAP93314.1 - 6e-08 32.0 2.1 1.5e-05 24.1 1.6 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein RYDR_ITPR PF01365.16 GAP93314.1 - 0.17 11.0 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 RIH domain Ank_2 PF12796.2 GAP93315.1 - 1.4e-57 192.0 0.0 7.2e-20 71.1 0.5 4.6 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAP93315.1 - 1.7e-51 169.5 2.7 3.7e-07 29.6 0.0 9.7 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 GAP93315.1 - 3.8e-40 135.5 0.2 5.7e-10 39.4 0.1 6.8 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP93315.1 - 4.6e-37 125.1 5.1 2.7e-09 36.9 0.1 7.1 3 1 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP93315.1 - 2.5e-33 110.7 0.0 0.016 15.4 0.0 9.1 8 0 0 8 8 8 8 Ankyrin repeat PNP_UDP_1 PF01048.15 GAP93315.1 - 8e-17 60.9 0.0 1.5e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily DUF1620 PF07774.8 GAP93316.1 - 1.2e-63 214.2 0.0 2e-63 213.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 GAP93316.1 - 9.3e-16 58.0 10.2 2.7e-12 46.6 0.5 3.4 3 1 0 3 3 3 2 PQQ-like domain PQQ PF01011.16 GAP93316.1 - 2.4e-05 23.6 7.8 0.0037 16.7 0.0 5.2 6 0 0 6 6 6 2 PQQ enzyme repeat zf-PARP PF00645.13 GAP93317.1 - 1.5e-19 69.9 0.1 3.5e-19 68.8 0.1 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PI3_PI4_kinase PF00454.22 GAP93318.1 - 4.2e-48 163.8 0.0 1.3e-47 162.3 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 GAP93318.1 - 2e-38 132.3 3.2 2.5e-38 131.9 1.3 1.9 2 0 0 2 2 2 1 FAT domain UME PF08064.8 GAP93318.1 - 1.3e-23 82.9 2.5 3.6e-22 78.3 0.0 3.3 4 0 0 4 4 4 1 UME (NUC010) domain FATC PF02260.15 GAP93318.1 - 1.6e-17 62.6 0.2 5e-17 61.0 0.0 2.0 2 0 0 2 2 2 1 FATC domain COX16 PF14138.1 GAP93319.1 - 1.3e-32 111.7 0.1 2e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 HTH_17 PF12728.2 GAP93319.1 - 0.067 13.4 0.2 0.11 12.7 0.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2371 PF10177.4 GAP93319.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) TPR_3 PF07720.7 GAP93319.1 - 0.14 12.0 1.2 0.21 11.4 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Amidase PF01425.16 GAP93321.1 - 1.3e-54 185.7 0.1 5e-50 170.6 0.1 2.2 1 1 1 2 2 2 2 Amidase p450 PF00067.17 GAP93322.1 - 9.6e-51 172.7 0.0 1.9e-50 171.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 UbiA PF01040.13 GAP93323.1 - 8.1e-11 41.6 10.2 2.4e-07 30.2 3.7 2.4 2 1 0 2 2 2 2 UbiA prenyltransferase family AMP-binding PF00501.23 GAP93324.1 - 2e-29 102.2 0.0 2.9e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 GAP93324.1 - 2.5e-21 75.7 0.0 4.2e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 GAP93324.1 - 0.00029 20.3 0.0 0.13 11.6 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 GAP93324.1 - 0.00055 20.1 0.0 0.0015 18.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Semialdhyde_dh PF01118.19 GAP93324.1 - 0.0021 18.3 0.1 0.0053 17.0 0.1 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 GAP93324.1 - 0.11 12.4 0.1 0.95 9.4 0.1 2.5 1 1 0 1 1 1 0 NADH(P)-binding NmrA PF05368.8 GAP93324.1 - 0.13 11.4 0.1 0.21 10.8 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family FAD_binding_3 PF01494.14 GAP93325.1 - 2.8e-20 72.6 0.3 1.9e-19 69.9 0.2 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAP93325.1 - 4.4e-06 25.8 1.0 0.061 12.2 0.1 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAP93325.1 - 0.00015 21.6 0.0 0.00047 20.1 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.16 GAP93325.1 - 0.0019 17.7 0.0 0.0045 16.5 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 GAP93325.1 - 0.0033 16.5 0.0 0.0054 15.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 GAP93325.1 - 0.0088 16.4 0.0 0.038 14.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 GAP93325.1 - 0.018 14.1 1.2 0.89 8.5 0.0 3.0 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 GAP93325.1 - 0.025 13.2 0.0 0.041 12.5 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Lycopene_cycl PF05834.7 GAP93325.1 - 0.069 12.0 0.4 0.57 9.0 0.3 2.1 1 1 0 1 1 1 0 Lycopene cyclase protein DUF747 PF05346.6 GAP93326.1 - 4.4e-128 426.9 6.6 5.9e-128 426.5 4.5 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family Beta-lactamase PF00144.19 GAP93327.1 - 1.4e-36 126.2 0.0 2.2e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DAO PF01266.19 GAP93328.1 - 2.5e-57 194.3 1.8 3e-57 194.1 1.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAP93328.1 - 5.9e-06 26.4 0.3 0.093 12.7 0.4 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAP93328.1 - 0.0037 16.1 3.7 0.043 12.6 1.5 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 GAP93328.1 - 0.014 15.4 4.0 0.035 14.1 1.6 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 GAP93328.1 - 0.065 13.0 1.5 8.4 6.1 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.9 GAP93328.1 - 0.066 11.6 1.7 0.097 11.1 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Etmic-2 PF06670.6 GAP93328.1 - 0.54 8.9 3.5 0.22 10.2 0.3 1.7 2 0 0 2 2 2 0 Microneme protein Etmic-2 Glyoxalase_4 PF13669.1 GAP93330.1 - 0.011 15.7 0.0 0.016 15.1 0.0 1.3 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAP93330.1 - 0.013 16.1 0.1 0.017 15.7 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain Glyoxalase PF00903.20 GAP93330.1 - 0.048 13.6 0.0 0.053 13.5 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 GAP93330.1 - 0.083 12.7 0.1 0.12 12.3 0.0 1.3 1 1 0 1 1 1 0 Glyoxalase-like domain CENP-F_leu_zip PF10473.4 GAP93331.1 - 0.0073 16.1 0.5 0.0073 16.1 0.3 1.8 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2046 PF09755.4 GAP93331.1 - 0.042 12.7 1.4 0.068 12.0 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DUF4407 PF14362.1 GAP93331.1 - 0.071 12.0 0.5 0.15 10.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Striatin PF08232.7 GAP93331.1 - 0.23 11.7 6.0 0.57 10.5 0.0 3.1 3 1 0 3 3 3 0 Striatin family DivIC PF04977.10 GAP93331.1 - 1.6 8.2 4.3 0.41 10.1 0.1 2.1 2 0 0 2 2 2 0 Septum formation initiator DUF1996 PF09362.5 GAP93332.1 - 2.6e-51 174.5 0.1 3.1e-51 174.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) RRM_6 PF14259.1 GAP93333.1 - 6.8e-09 35.5 0.0 1.5e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAP93333.1 - 2.2e-07 30.4 0.1 4e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAP93333.1 - 0.0026 17.4 0.0 0.0043 16.7 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif ANTH PF07651.11 GAP93333.1 - 0.041 12.5 0.1 0.14 10.8 0.0 1.8 2 0 0 2 2 2 0 ANTH domain MFS_1 PF07690.11 GAP93334.1 - 3.4e-17 62.2 44.9 3.6e-16 58.8 31.1 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3176 PF11374.3 GAP93337.1 - 5.1e-30 103.5 0.4 5.1e-30 103.5 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) HET PF06985.6 GAP93338.1 - 1.3e-36 125.7 0.1 2.1e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ThuA PF06283.6 GAP93339.1 - 1.7e-26 93.2 0.0 1.9e-26 93.1 0.0 1.0 1 0 0 1 1 1 1 Trehalose utilisation DUF1355 PF07090.6 GAP93339.1 - 0.077 12.3 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1355) Amidase PF01425.16 GAP93341.1 - 1.9e-93 313.7 1.2 2.6e-93 313.2 0.8 1.1 1 0 0 1 1 1 1 Amidase Aldo_ket_red PF00248.16 GAP93342.1 - 2.2e-64 217.0 0.0 2.7e-64 216.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TrkH PF02386.11 GAP93344.1 - 5.6e-82 275.1 8.2 4.2e-80 268.9 1.5 2.3 2 0 0 2 2 2 2 Cation transport protein KR PF08659.5 GAP93345.1 - 1e-51 175.1 0.3 2e-51 174.2 0.2 1.5 1 0 0 1 1 1 1 KR domain ketoacyl-synt PF00109.21 GAP93345.1 - 9.2e-51 172.7 0.0 2.2e-50 171.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 GAP93345.1 - 4.1e-48 164.0 0.0 6.1e-48 163.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 GAP93345.1 - 6.9e-45 153.7 0.0 1e-44 153.1 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 GAP93345.1 - 5.9e-42 143.4 1.1 2.1e-41 141.5 0.1 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAP93345.1 - 1.8e-34 118.1 0.1 5.1e-34 116.6 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 GAP93345.1 - 2.2e-16 59.6 0.0 5.3e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAP93345.1 - 3.3e-09 37.7 0.0 1.1e-08 36.0 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP93345.1 - 4.5e-08 32.8 0.1 1.1e-07 31.6 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 GAP93345.1 - 8.5e-06 25.9 0.6 3.7e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site ACP_syn_III PF08545.5 GAP93345.1 - 0.032 13.8 0.4 0.1 12.2 0.3 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 GAP93345.1 - 0.15 10.9 0.4 0.52 9.2 0.0 1.9 2 0 0 2 2 2 0 Thiolase, N-terminal domain APC8 PF04049.8 GAP93346.1 - 5.2e-33 113.7 0.3 2.1e-32 111.7 0.0 2.1 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_11 PF13414.1 GAP93346.1 - 1.9e-19 69.0 12.3 3.5e-08 32.9 0.4 5.2 5 1 1 6 6 6 3 TPR repeat TPR_1 PF00515.23 GAP93346.1 - 7.4e-19 66.5 15.3 5.2e-07 28.9 0.1 7.1 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 GAP93346.1 - 1.7e-15 55.5 22.4 0.00016 21.3 0.0 9.0 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_12 PF13424.1 GAP93346.1 - 1.4e-13 50.5 13.2 0.00021 21.1 0.2 6.9 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 GAP93346.1 - 8.5e-13 47.0 8.6 0.021 14.5 0.0 6.5 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 GAP93346.1 - 3.4e-12 45.8 23.6 0.032 14.8 0.1 9.0 8 2 2 10 10 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 GAP93346.1 - 7.2e-10 39.2 22.4 0.00067 20.2 0.8 7.4 4 2 2 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 GAP93346.1 - 5.9e-08 32.7 11.5 0.0013 18.8 0.0 6.0 6 2 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 GAP93346.1 - 9.9e-07 28.4 8.4 0.22 11.8 0.2 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAP93346.1 - 1.1e-06 27.9 17.4 0.019 14.7 0.2 6.8 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAP93346.1 - 3.7e-05 23.9 14.8 0.36 11.2 0.0 6.9 5 1 3 8 8 8 2 Tetratricopeptide repeat TPR_10 PF13374.1 GAP93346.1 - 0.11 12.5 8.2 0.67 9.9 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAP93346.1 - 0.11 13.0 14.4 28 5.4 0.4 6.9 7 0 0 7 7 6 0 Tetratricopeptide repeat ChAPs PF09295.5 GAP93346.1 - 0.14 10.8 0.0 0.38 9.4 0.0 1.6 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Sel1 PF08238.7 GAP93346.1 - 0.48 11.1 7.4 13 6.5 0.0 4.8 5 0 0 5 5 4 0 Sel1 repeat TPR_9 PF13371.1 GAP93346.1 - 1.3 8.9 8.3 1.8 8.4 0.0 4.8 3 1 2 5 5 5 0 Tetratricopeptide repeat DCP1 PF06058.8 GAP93347.1 - 2.2e-13 50.2 0.0 3.9e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Dcp1-like decapping family PAXIP1_C PF15364.1 GAP93347.1 - 0.046 13.6 3.2 0.092 12.6 2.2 1.5 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Suf PF05843.9 GAP93347.1 - 0.45 10.2 5.5 0.66 9.6 3.8 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 GAP93347.1 - 2.1 6.4 25.9 2.9 6.0 17.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BAF1_ABF1 PF04684.8 GAP93347.1 - 4.8 5.9 23.8 7.6 5.2 16.5 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Exo_endo_phos PF03372.18 GAP93348.1 - 3.1e-13 50.2 0.1 1.4e-12 48.1 0.0 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.20 GAP93349.1 - 6.1e-10 38.6 0.0 4.4e-09 35.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP93349.1 - 4.2e-06 26.0 0.0 7.5e-05 21.9 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Glyco_transf_15 PF01793.11 GAP93351.1 - 3.5e-101 338.4 9.6 4.8e-100 334.7 6.6 2.0 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Gly_transf_sug PF04488.10 GAP93352.1 - 7.8e-10 39.0 0.0 1.8e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 GAP93352.1 - 2.8e-05 22.7 0.1 0.00012 20.7 0.0 1.7 2 0 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 GAP93352.1 - 0.00088 18.5 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein OppC_N PF12911.2 GAP93352.1 - 0.018 14.3 1.7 0.021 14.1 0.0 1.9 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C AA_permease PF00324.16 GAP93354.1 - 7.8e-114 380.6 36.2 9.4e-114 380.3 25.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAP93354.1 - 4.5e-23 81.4 35.6 6.1e-23 81.0 24.7 1.1 1 0 0 1 1 1 1 Amino acid permease Orthoreo_P10 PF07204.6 GAP93354.1 - 0.81 9.4 8.4 0.049 13.3 1.1 2.3 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 PLDc_2 PF13091.1 GAP93355.1 - 9.7e-19 67.3 0.0 1.8e-12 47.0 0.0 3.3 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.17 GAP93355.1 - 0.024 14.4 0.0 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 Phospholipase D Active site motif Regulator_TrmB PF11495.3 GAP93355.1 - 0.057 12.3 0.8 1.2 8.0 0.0 2.9 4 0 0 4 4 4 0 Archaeal transcriptional regulator TrmB p450 PF00067.17 GAP93357.1 - 1.2e-23 83.3 0.0 2.8e-23 82.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 GAP93358.1 - 2.4e-11 42.9 36.6 6e-11 41.6 23.3 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF872 PF05915.7 GAP93358.1 - 0.15 11.9 0.8 3.4 7.5 0.0 3.0 3 1 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) p450 PF00067.17 GAP93359.1 - 3.3e-31 108.3 0.0 1.5e-30 106.1 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 GAP93360.1 - 2.6e-12 46.4 0.0 5.3e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAP93360.1 - 1.1e-05 25.1 0.0 2.9e-05 23.7 0.0 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain AMP-binding PF00501.23 GAP93361.1 - 2.1e-79 266.9 0.1 3.7e-79 266.0 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 GAP93361.1 - 1.4e-76 257.3 0.1 5.1e-76 255.5 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.15 GAP93361.1 - 1.6e-53 181.4 0.0 3.2e-53 180.5 0.0 1.5 1 0 0 1 1 1 1 Condensation domain KR PF08659.5 GAP93361.1 - 1.1e-52 178.3 0.0 4.7e-51 173.0 0.1 3.2 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.16 GAP93361.1 - 8.4e-49 166.6 0.3 1.6e-48 165.6 0.2 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 GAP93361.1 - 5.9e-46 156.9 0.0 1.1e-45 156.0 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 GAP93361.1 - 1.3e-43 148.8 5.0 1.3e-41 142.3 0.1 3.5 4 0 0 4 4 3 2 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAP93361.1 - 8.7e-28 96.5 0.0 3.4e-27 94.6 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 GAP93361.1 - 1.1e-22 80.1 0.0 1.9e-21 76.1 0.0 2.5 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 GAP93361.1 - 1.3e-19 70.1 0.2 9.1e-10 38.6 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 GAP93361.1 - 1.7e-17 63.6 0.0 7.8e-17 61.5 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP93361.1 - 7.7e-13 48.4 0.0 1.8e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 GAP93361.1 - 4.1e-11 43.0 0.2 2.4e-10 40.5 0.0 2.6 3 0 0 3 3 1 1 HxxPF-repeated domain Methyltransf_31 PF13847.1 GAP93361.1 - 1.8e-10 40.5 0.0 6.3e-10 38.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP93361.1 - 6e-09 36.2 0.0 1.7e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP93361.1 - 1.1e-08 35.5 0.0 2.6e-07 31.2 0.0 3.2 3 0 0 3 3 3 1 Methyltransferase domain 3Beta_HSD PF01073.14 GAP93361.1 - 1.5e-08 33.7 0.0 8.7e-05 21.3 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAP93361.1 - 1.3e-07 31.3 0.0 0.0032 16.9 0.0 2.6 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Ubie_methyltran PF01209.13 GAP93361.1 - 2.2e-05 23.6 0.0 5.5e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 GAP93361.1 - 4.9e-05 22.4 0.0 0.00011 21.2 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 GAP93361.1 - 0.073 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase GFO_IDH_MocA PF01408.17 GAP93362.1 - 3.1e-20 72.8 0.4 6.1e-20 71.9 0.2 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 GAP93362.1 - 0.00012 21.8 0.0 0.0003 20.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.17 GAP93363.1 - 3.8e-17 62.9 0.2 5.7e-17 62.3 0.2 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 GAP93363.1 - 0.066 13.6 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Actin PF00022.14 GAP93365.1 - 3.9e-99 331.7 0.0 4.6e-99 331.5 0.0 1.0 1 0 0 1 1 1 1 Actin SBBP PF06739.6 GAP93365.1 - 0.058 13.1 0.1 0.31 10.8 0.0 2.1 2 0 0 2 2 2 0 Beta-propeller repeat F-box PF00646.28 GAP93367.1 - 0.032 13.8 0.2 0.42 10.3 0.0 2.6 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.2 GAP93367.1 - 0.092 12.4 0.0 0.27 10.9 0.0 1.9 1 0 0 1 1 1 0 F-box-like UFD1 PF03152.9 GAP93368.1 - 1.6e-23 82.7 0.0 5.8e-19 67.9 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 UPF0547 PF10571.4 GAP93368.1 - 4 7.2 11.2 0.27 10.9 1.3 3.5 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-C2H2_4 PF13894.1 GAP93368.1 - 6.1 7.4 19.5 0.77 10.2 0.7 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger Tyrosinase PF00264.15 GAP93369.1 - 3e-34 119.1 5.3 3e-34 119.1 3.7 1.8 2 0 0 2 2 2 1 Common central domain of tyrosinase GF_recep_IV PF14843.1 GAP93369.1 - 0.078 12.5 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Growth factor receptor domain IV Methyltransf_2 PF00891.13 GAP93370.1 - 4.6e-33 114.4 0.0 7.7e-33 113.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 GAP93370.1 - 8.5e-05 23.1 0.0 0.00019 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP93370.1 - 0.072 12.6 0.0 0.97 9.0 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain HTH_AsnC-type PF13404.1 GAP93370.1 - 0.14 11.6 0.7 0.6 9.6 0.0 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DDE_1 PF03184.14 GAP93371.1 - 2.3e-35 121.7 0.6 2.3e-35 121.7 0.4 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 GAP93371.1 - 4.2e-09 36.0 0.3 1.8e-08 34.0 0.2 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Aldo_ket_red PF00248.16 GAP93372.1 - 3.7e-54 183.4 0.0 4.7e-54 183.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Beta-lactamase PF00144.19 GAP93373.1 - 9.4e-29 100.4 0.1 1.5e-28 99.8 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S49_N PF08496.5 GAP93374.1 - 2.6 7.8 7.3 0.51 10.1 1.4 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Cupin_2 PF07883.6 GAP93375.1 - 3.8e-07 29.4 0.0 6.6e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 GAP93375.1 - 0.0056 16.0 0.0 0.01 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Arylsulfotran_2 PF14269.1 GAP93376.1 - 6.2e-50 170.0 1.7 8e-50 169.6 1.2 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 GAP93376.1 - 8.6e-16 57.5 0.3 2.4e-15 56.0 0.2 1.7 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Y_phosphatase3 PF13350.1 GAP93377.1 - 7.9e-41 140.0 0.0 1.7e-38 132.4 0.0 2.4 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 GAP93377.1 - 0.00027 20.3 0.0 0.00072 18.9 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 GAP93377.1 - 0.00086 18.7 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 GAP93377.1 - 0.0032 17.0 0.0 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.9 GAP93377.1 - 0.012 14.4 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain UPF0075 PF03702.9 GAP93377.1 - 0.12 11.2 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) Glyco_hydro_20 PF00728.17 GAP93378.1 - 5.1e-17 62.0 1.5 5.7e-11 42.1 0.0 3.3 1 1 1 3 3 3 2 Glycosyl hydrolase family 20, catalytic domain WD40 PF00400.27 GAP93379.1 - 4.3e-78 254.6 16.5 9.2e-12 44.3 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 GAP93379.1 - 8.4e-09 34.0 4.4 0.00027 19.2 0.1 4.4 3 2 1 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAP93379.1 - 0.00022 20.1 0.0 0.43 9.2 0.0 3.3 1 1 2 3 3 3 3 Nup133 N terminal like LisH PF08513.6 GAP93379.1 - 0.035 13.8 0.0 0.077 12.7 0.0 1.6 1 0 0 1 1 1 0 LisH CLASP_N PF12348.3 GAP93380.1 - 0.00018 20.9 0.0 0.00068 19.0 0.0 1.9 2 0 0 2 2 2 1 CLASP N terminal Adaptin_N PF01602.15 GAP93380.1 - 0.0011 17.4 0.8 0.45 8.7 0.0 2.7 2 1 1 3 3 3 2 Adaptin N terminal region HEAT PF02985.17 GAP93380.1 - 0.0017 18.2 3.7 1.8 8.8 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.2 GAP93380.1 - 0.0042 16.9 0.1 0.014 15.2 0.0 1.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HsbA PF12296.3 GAP93380.1 - 0.0093 15.8 0.3 0.082 12.7 0.1 2.7 3 0 0 3 3 3 1 Hydrophobic surface binding protein A APG6 PF04111.7 GAP93380.1 - 0.2 10.7 11.4 0.98 8.4 7.0 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 GAP93380.1 - 0.2 11.2 7.7 0.69 9.4 5.4 1.9 1 0 0 1 1 1 0 IncA protein TPR_MLP1_2 PF07926.7 GAP93380.1 - 0.42 10.3 10.3 0.055 13.2 2.3 2.9 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Rootletin PF15035.1 GAP93380.1 - 0.64 9.9 17.9 1.4 8.8 4.4 3.2 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion ADIP PF11559.3 GAP93380.1 - 2 8.2 12.6 6.3 6.6 8.7 1.8 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 GAP93380.1 - 3.5 6.4 9.4 8.5 5.2 6.5 1.6 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Cupin_8 PF13621.1 GAP93381.1 - 0.0085 15.6 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Methyltransf_11 PF08241.7 GAP93382.1 - 7.8e-13 48.7 0.0 1.3e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP93382.1 - 5.9e-11 42.9 0.2 1.5e-10 41.6 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP93382.1 - 1.4e-10 41.4 0.0 2.2e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP93382.1 - 7.3e-10 39.2 0.0 1.2e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP93382.1 - 3.6e-09 36.5 0.0 5.1e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAP93382.1 - 4.7e-09 36.0 0.0 6.7e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP93382.1 - 1.1e-07 31.9 0.1 1.6e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 GAP93382.1 - 5.7e-05 22.3 0.1 7.1e-05 22.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 GAP93382.1 - 0.00014 21.3 0.1 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 GAP93382.1 - 0.00032 19.9 0.0 0.00042 19.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.6 GAP93382.1 - 0.0059 15.3 0.0 0.008 14.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_29 PF03141.11 GAP93382.1 - 0.0079 14.5 0.0 0.0093 14.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase N2227 PF07942.7 GAP93382.1 - 0.042 12.7 0.0 0.063 12.2 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein Methyltransf_32 PF13679.1 GAP93382.1 - 0.062 12.9 0.0 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.21 GAP93382.1 - 0.12 11.9 0.6 0.3 10.6 0.4 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DIOX_N PF14226.1 GAP93383.1 - 1.3e-20 74.0 0.1 1.8e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAP93383.1 - 6.4e-16 58.4 0.0 1.2e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HET PF06985.6 GAP93384.1 - 4.2e-22 78.8 9.8 1e-19 71.1 5.1 3.2 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) AAA_16 PF13191.1 GAP93384.1 - 7.9e-09 35.7 0.3 2.5e-08 34.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 GAP93384.1 - 1.4e-08 34.6 0.0 3.1e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAP93384.1 - 3.1e-05 24.1 0.0 0.00021 21.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 GAP93384.1 - 0.011 15.9 0.0 0.044 13.9 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 GAP93384.1 - 0.012 15.7 0.1 0.11 12.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Glyco_hydro_81 PF03639.8 GAP93386.1 - 5.9e-90 302.2 8.6 8.4e-90 301.7 6.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Fascin PF06268.8 GAP93386.1 - 0.0011 19.0 0.0 0.0046 17.0 0.0 2.0 1 1 1 2 2 2 1 Fascin domain RicinB_lectin_2 PF14200.1 GAP93386.1 - 0.012 16.0 0.9 0.73 10.2 0.1 3.0 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain-like FAD_binding_4 PF01565.18 GAP93388.1 - 2.4e-08 33.5 2.9 4.9e-08 32.5 2.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAP93388.1 - 0.00028 20.7 0.1 0.00067 19.5 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Porin_3 PF01459.17 GAP93391.1 - 3.7e-64 216.6 9.5 4.2e-64 216.4 6.6 1.0 1 0 0 1 1 1 1 Eukaryotic porin PTS_EIIC PF02378.13 GAP93391.1 - 0.048 12.4 0.9 0.076 11.8 0.6 1.3 1 0 0 1 1 1 0 Phosphotransferase system, EIIC eIF-3c_N PF05470.7 GAP93393.1 - 0.24 9.4 4.3 0.34 8.9 3.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SHNi-TPR PF10516.4 GAP93394.1 - 2.9e-15 55.2 0.6 1e-14 53.4 0.0 2.3 2 0 0 2 2 2 1 SHNi-TPR TPR_11 PF13414.1 GAP93394.1 - 4.1e-08 32.7 3.4 0.00011 21.7 0.1 3.2 3 1 0 3 3 3 2 TPR repeat TPR_12 PF13424.1 GAP93394.1 - 3.6e-07 30.0 3.2 0.0017 18.2 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 GAP93394.1 - 3.1e-06 27.2 0.2 0.00019 21.5 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 GAP93394.1 - 3.4e-06 27.5 7.4 3.7e-06 27.4 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAP93394.1 - 0.00015 22.0 0.1 0.0011 19.2 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAP93394.1 - 0.0012 18.5 8.4 0.51 10.3 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAP93394.1 - 0.0024 17.9 0.1 0.2 11.9 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAP93394.1 - 0.055 13.1 3.3 3.6 7.3 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 GAP93394.1 - 0.14 11.9 0.2 0.37 10.6 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat CDC50 PF03381.10 GAP93395.1 - 3.6e-79 265.8 0.0 4.8e-79 265.4 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family zf-C2H2_2 PF12756.2 GAP93396.1 - 8.2e-26 90.0 0.5 1.3e-25 89.4 0.3 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) NOA36 PF06524.7 GAP93396.1 - 0.41 9.8 6.3 0.65 9.2 4.4 1.3 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 GAP93396.1 - 2.4 7.6 10.0 3.9 6.9 7.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin CorA PF01544.13 GAP93397.1 - 4.9e-06 25.7 0.3 1e-05 24.7 0.2 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein K-box PF01486.12 GAP93397.1 - 0.11 12.2 0.1 0.31 10.8 0.1 1.7 1 0 0 1 1 1 0 K-box region Thr_synth_N PF14821.1 GAP93398.1 - 2.3e-28 98.0 0.0 7.4e-28 96.3 0.0 1.9 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 GAP93398.1 - 3.5e-22 79.0 0.0 1.5e-21 76.9 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NAD_binding_4 PF07993.7 GAP93399.1 - 1.4e-35 122.3 0.0 2.2e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 GAP93399.1 - 1.5e-33 115.8 0.0 4e-33 114.4 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 GAP93399.1 - 3.5e-09 36.4 0.0 6.5e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 GAP93399.1 - 6.5e-06 25.9 0.1 1.8e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 GAP93399.1 - 3.2e-05 23.9 0.2 9.3e-05 22.3 0.1 1.8 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.20 GAP93399.1 - 0.0002 21.5 0.0 0.00041 20.5 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 GAP93399.1 - 0.092 11.4 0.0 0.21 10.2 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.11 GAP93400.1 - 3.3e-34 118.1 23.7 3.3e-34 118.1 16.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAP93400.1 - 1.2e-11 43.9 14.3 1.7e-11 43.3 9.9 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1049 PF06305.6 GAP93400.1 - 0.52 9.8 2.5 1.5 8.3 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Bromodomain PF00439.20 GAP93402.1 - 9.4e-35 118.3 6.8 2.1e-18 66.0 0.8 3.0 2 1 1 3 3 3 2 Bromodomain BAH PF01426.13 GAP93402.1 - 5.8e-18 64.7 1.8 8.3e-18 64.2 0.7 1.7 2 0 0 2 2 2 1 BAH domain CDC45 PF02724.9 GAP93402.1 - 0.00066 17.8 5.4 0.00066 17.8 3.8 2.6 3 0 0 3 3 3 1 CDC45-like protein OTU PF02338.14 GAP93403.1 - 6e-08 33.3 0.0 9.8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease DUF1547 PF07577.6 GAP93403.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1547) PAS_9 PF13426.1 GAP93404.1 - 6.5e-31 106.7 0.0 4.6e-15 55.8 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 GAP93404.1 - 1e-19 70.4 0.0 1.7e-11 44.0 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS PF00989.19 GAP93404.1 - 8.4e-16 57.7 0.0 1.1e-05 25.1 0.0 3.6 3 0 0 3 3 3 3 PAS fold GATA PF00320.22 GAP93404.1 - 6.3e-15 54.2 9.1 1.3e-14 53.1 6.3 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_11 PF14598.1 GAP93404.1 - 1.5e-14 53.9 0.0 2.1e-06 27.6 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 GAP93404.1 - 1.8e-08 34.3 0.0 0.0014 18.6 0.0 3.3 3 0 0 3 3 3 2 PAS fold PAS_2 PF08446.6 GAP93404.1 - 0.00021 21.7 0.0 0.52 10.7 0.0 3.8 3 1 0 3 3 3 1 PAS fold FmdA_AmdA PF03069.10 GAP93405.1 - 1.3e-152 507.8 0.0 1.5e-152 507.5 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family EI24 PF07264.6 GAP93406.1 - 1.9e-07 30.7 11.9 5.6e-06 25.9 8.2 2.7 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Fructosamin_kin PF03881.9 GAP93407.1 - 9.1e-34 116.7 0.0 1.1e-33 116.4 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 GAP93407.1 - 7.9e-07 29.0 0.0 1.2e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family MFS_1 PF07690.11 GAP93408.1 - 2.3e-43 148.2 41.6 1.4e-40 139.0 27.5 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAP93408.1 - 9.8e-20 70.2 20.9 1.3e-19 69.8 14.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAP93408.1 - 1.2e-17 63.7 12.4 1.2e-17 63.7 8.6 3.4 3 1 1 4 4 4 1 Sugar (and other) transporter MFS_2 PF13347.1 GAP93408.1 - 1.1e-06 27.3 4.4 1.1e-06 27.3 3.1 4.3 3 1 0 3 3 3 2 MFS/sugar transport protein PALP PF00291.20 GAP93409.1 - 7.8e-24 84.4 0.0 1.4e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.15 GAP93409.1 - 2.3e-06 27.9 0.0 5.3e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain FTA2 PF13095.1 GAP93410.1 - 1e-28 100.4 0.0 1.5e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Ifi-6-16 PF06140.8 GAP93411.1 - 0.00081 19.1 31.4 0.00081 19.1 21.8 2.2 1 1 1 2 2 2 1 Interferon-induced 6-16 family Ank_2 PF12796.2 GAP93412.1 - 2.6e-38 130.2 1.2 6.8e-14 51.9 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAP93412.1 - 1.3e-33 113.0 9.8 4e-08 32.6 0.1 6.0 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 GAP93412.1 - 4e-26 90.4 6.8 1.1e-07 31.8 0.1 5.3 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP93412.1 - 1.5e-21 74.3 3.0 6.4e-05 22.8 0.1 5.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 GAP93412.1 - 7.1e-21 74.1 5.5 6.1e-07 29.7 0.1 4.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) HET PF06985.6 GAP93412.1 - 0.081 13.0 9.6 0.78 9.8 2.6 3.1 2 1 0 2 2 2 0 Heterokaryon incompatibility protein (HET) DUF724 PF05266.9 GAP93412.1 - 0.75 9.3 7.9 1.4 8.5 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) APG6 PF04111.7 GAP93412.1 - 2 7.4 9.2 3 6.8 6.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 GHMP_kinases_N PF00288.21 GAP93414.1 - 1.6e-16 60.1 1.3 4.5e-16 58.6 0.9 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 GAP93414.1 - 2.2e-06 27.7 0.0 6.4e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal HET PF06985.6 GAP93415.1 - 1.5e-19 70.5 0.0 2.8e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 GAP93416.1 - 7.7e-23 80.9 0.0 1.5e-22 80.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP93416.1 - 9.7e-19 67.4 0.0 1.7e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAP93417.1 - 4.3e-19 68.6 0.0 6.1e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAP93417.1 - 1.6e-07 30.6 0.1 6.2e-07 28.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase FAD_binding_3 PF01494.14 GAP93418.1 - 4.1e-12 45.8 3.6 8e-05 21.8 0.2 3.1 3 0 0 3 3 3 3 FAD binding domain Pyr_redox PF00070.22 GAP93418.1 - 0.019 15.3 0.1 0.043 14.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pectate_lyase_3 PF12708.2 GAP93420.1 - 2e-69 234.1 14.9 1.8e-54 185.2 7.0 2.9 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 GAP93420.1 - 0.022 14.2 0.5 0.096 12.1 0.2 2.3 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase PNTB PF02233.11 GAP93422.1 - 2.9e-170 567.0 27.0 2.9e-170 567.0 18.7 1.6 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 GAP93422.1 - 1.3e-53 181.0 0.4 2.7e-53 179.9 0.3 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 GAP93422.1 - 9.4e-49 164.8 0.1 9.4e-49 164.8 0.0 2.3 3 0 0 3 3 2 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 GAP93422.1 - 1.5e-31 108.4 3.2 1.5e-31 108.4 2.2 5.2 4 2 1 6 6 6 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 GAP93422.1 - 0.0013 17.8 0.2 0.92 8.6 0.0 2.9 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 GAP93422.1 - 0.0031 17.0 0.8 0.023 14.2 0.1 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Fumerase PF05681.9 GAP93422.1 - 0.0073 15.4 0.1 0.013 14.5 0.1 1.3 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) TPP_enzyme_M PF00205.17 GAP93422.1 - 0.019 14.7 0.9 0.078 12.7 0.3 2.5 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Shikimate_DH PF01488.15 GAP93422.1 - 0.024 14.7 3.6 10 6.2 0.0 4.2 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase Methyltransf_31 PF13847.1 GAP93422.1 - 0.024 14.2 0.0 0.077 12.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox_2 PF07992.9 GAP93422.1 - 0.028 14.2 1.4 0.095 12.5 0.4 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_18 PF12847.2 GAP93422.1 - 0.14 12.7 0.0 0.49 10.9 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_8 PF13450.1 GAP93422.1 - 4.7 7.3 7.7 0.76 9.8 1.3 2.9 3 1 0 3 3 2 0 NAD(P)-binding Rossmann-like domain MIP-T3 PF10243.4 GAP93423.1 - 7.5 4.8 29.0 9.3 4.5 20.1 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ras PF00071.17 GAP93424.1 - 1.2e-31 109.2 0.3 1.5e-31 108.9 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAP93424.1 - 8.3e-21 74.7 0.1 3.3e-20 72.7 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAP93424.1 - 5.1e-07 29.0 0.1 7e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAP93424.1 - 2e-05 23.8 0.3 2.7e-05 23.4 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF1590 PF07629.6 GAP93424.1 - 0.0011 18.4 0.0 0.0028 17.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1590) DLIC PF05783.6 GAP93424.1 - 0.0017 17.0 0.0 1.3 7.6 0.0 2.2 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) G-alpha PF00503.15 GAP93424.1 - 0.04 12.5 2.4 0.21 10.2 0.0 2.6 1 1 2 3 3 3 0 G-protein alpha subunit MMR_HSR1 PF01926.18 GAP93424.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.24 GAP93427.1 - 2.9e-17 63.1 0.0 5.6e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAP93427.1 - 1.6e-05 24.9 0.3 8.9e-05 22.5 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 GAP93427.1 - 3.7e-05 23.3 0.0 8.2e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 GAP93427.1 - 6e-05 23.8 0.5 0.0009 20.0 0.3 2.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAP93427.1 - 0.00013 22.1 0.4 0.0023 18.0 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.9 GAP93427.1 - 0.0002 21.0 0.0 0.00042 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 GAP93427.1 - 0.0022 17.6 0.0 0.0074 15.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAP93427.1 - 0.0032 17.0 0.0 0.0054 16.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zot PF05707.7 GAP93427.1 - 0.0088 15.5 0.1 0.47 9.8 0.1 2.3 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_33 PF13671.1 GAP93427.1 - 0.027 14.3 0.0 0.063 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 GAP93427.1 - 0.035 13.5 0.0 0.089 12.2 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 GAP93427.1 - 0.037 13.9 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain FHA PF00498.21 GAP93427.1 - 0.044 13.8 0.0 0.49 10.5 0.0 2.4 2 0 0 2 2 2 0 FHA domain AAA_18 PF13238.1 GAP93427.1 - 0.054 13.7 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 GAP93427.1 - 0.092 11.8 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI CPT PF07931.7 GAP93427.1 - 0.12 11.9 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.1 GAP93427.1 - 0.26 11.2 2.4 0.83 9.5 0.0 2.7 3 2 1 4 4 4 0 AAA domain Cpn60_TCP1 PF00118.19 GAP93428.1 - 1.7e-144 482.0 0.1 2e-144 481.8 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GCV_H PF01597.14 GAP93429.1 - 1.2e-31 108.9 0.1 1.4e-31 108.6 0.1 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Porphobil_deam PF01379.15 GAP93430.1 - 1.9e-50 170.7 0.0 2.4e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 GAP93430.1 - 1.3e-19 70.0 1.2 2.9e-19 68.9 0.9 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Acetyltransf_1 PF00583.19 GAP93431.1 - 2.4e-12 46.6 0.1 4.6e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 GAP93431.1 - 1.8e-11 44.3 0.0 2.4e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAP93431.1 - 1.1e-07 31.9 0.0 2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAP93431.1 - 1.7e-05 24.9 0.0 3.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAP93431.1 - 0.0023 17.6 0.0 0.005 16.5 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 GAP93431.1 - 0.053 13.3 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PP2C PF00481.16 GAP93432.1 - 3.2e-22 79.1 0.0 1.1e-21 77.4 0.0 1.5 1 1 0 2 2 2 1 Protein phosphatase 2C p450 PF00067.17 GAP93433.1 - 1.2e-52 179.0 0.0 1.4e-52 178.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_31 PF13847.1 GAP93434.1 - 1e-23 83.5 0.0 1.3e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAP93434.1 - 1.3e-22 80.0 0.0 2.4e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP93434.1 - 9.5e-20 70.9 0.0 1.4e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAP93434.1 - 3.2e-17 62.4 0.0 5.9e-16 58.2 0.0 2.1 1 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 GAP93434.1 - 7.1e-16 58.7 0.0 1.2e-15 58.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAP93434.1 - 8.1e-15 55.0 0.0 1.4e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAP93434.1 - 1.3e-14 54.4 0.0 2.5e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 GAP93434.1 - 5.2e-10 39.2 0.0 7.3e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 GAP93434.1 - 5.2e-09 36.1 0.0 6.6e-09 35.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAP93434.1 - 5.8e-09 35.5 0.0 8.6e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 GAP93434.1 - 1.7e-08 33.8 0.0 2.3e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.7 GAP93434.1 - 5e-08 32.5 0.0 6.8e-08 32.1 0.0 1.3 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.1 GAP93434.1 - 4e-05 24.3 0.0 0.0001 23.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain GCD14 PF08704.5 GAP93434.1 - 0.0002 20.9 0.0 0.00029 20.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit RrnaAD PF00398.15 GAP93434.1 - 0.00063 18.8 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.12 GAP93434.1 - 0.00072 18.6 0.0 0.0016 17.5 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 GAP93434.1 - 0.0012 18.9 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase NodS PF05401.6 GAP93434.1 - 0.0019 17.6 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Nol1_Nop2_Fmu PF01189.12 GAP93434.1 - 0.0022 17.4 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_3 PF01596.12 GAP93434.1 - 0.004 16.2 0.0 0.0062 15.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_32 PF13679.1 GAP93434.1 - 0.0083 15.8 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 GAP93434.1 - 0.0085 15.2 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.6 GAP93434.1 - 0.0098 14.6 0.0 0.02 13.5 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Fibrillarin PF01269.12 GAP93434.1 - 0.04 12.8 0.0 0.064 12.1 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin TPMT PF05724.6 GAP93434.1 - 0.044 13.2 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_29 PF03141.11 GAP93434.1 - 0.064 11.5 0.0 0.081 11.2 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase ADH_zinc_N PF00107.21 GAP93434.1 - 0.067 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase CmcI PF04989.7 GAP93434.1 - 0.079 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase DOT1 PF08123.8 GAP93434.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Ferric_reduct PF01794.14 GAP93435.1 - 9.1e-18 64.5 11.6 9.1e-18 64.5 8.1 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 GAP93435.1 - 4e-10 39.4 0.0 9e-06 25.5 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.7 GAP93435.1 - 1.3e-07 31.7 0.0 0.0041 17.0 0.0 2.6 2 1 1 3 3 3 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 GAP93435.1 - 0.084 13.4 0.0 0.2 12.2 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain Ctr PF04145.10 GAP93436.1 - 3.4e-11 43.3 0.0 4.3e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family FPN1 PF06963.7 GAP93437.1 - 1.1e-121 406.3 22.2 1.2e-121 406.0 15.4 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Ank_2 PF12796.2 GAP93438.1 - 3.1e-22 78.7 0.1 1.1e-11 44.9 0.0 2.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAP93438.1 - 3.2e-09 36.1 0.3 2.2e-06 27.2 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 GAP93438.1 - 9e-08 32.1 0.1 0.037 14.2 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP93438.1 - 2.2e-07 30.4 0.1 7.9e-05 22.5 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 GAP93438.1 - 1.1e-05 25.7 0.1 0.00011 22.6 0.1 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Fig1 PF12351.3 GAP93439.1 - 6.3e-30 104.4 1.6 7.6e-30 104.1 1.1 1.0 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 GAP93439.1 - 0.0032 17.0 2.7 0.004 16.7 1.9 1.3 1 0 0 1 1 1 1 SUR7/PalI family Claudin_3 PF06653.6 GAP93439.1 - 0.63 9.7 4.8 0.69 9.6 0.6 2.2 2 0 0 2 2 2 0 Tight junction protein, Claudin-like Ndc1_Nup PF09531.5 GAP93439.1 - 0.74 8.1 5.0 0.9 7.8 3.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF485 PF04341.7 GAP93439.1 - 4.2 7.1 6.9 3.1 7.5 0.9 2.6 2 1 0 2 2 2 0 Protein of unknown function, DUF485 RRM_6 PF14259.1 GAP93440.1 - 1.4e-06 28.1 0.0 5.6e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAP93440.1 - 4.2e-06 26.3 0.0 0.00072 19.1 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAP93440.1 - 0.00044 20.0 0.1 0.0078 16.0 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U79_P34 PF03064.11 GAP93440.1 - 3 7.3 11.5 0.22 11.0 2.1 2.6 3 0 0 3 3 3 0 HSV U79 / HCMV P34 Aldedh PF00171.17 GAP93441.1 - 2.5e-135 451.4 0.0 2.8e-135 451.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAP93441.1 - 2.2e-06 26.6 0.0 4.7e-06 25.5 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) PBD PF00786.23 GAP93442.1 - 0.026 14.9 0.1 0.071 13.5 0.0 1.8 1 0 0 1 1 1 0 P21-Rho-binding domain Fungal_trans PF04082.13 GAP93443.1 - 9.9e-11 41.0 0.2 2.1e-10 39.9 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAP93443.1 - 0.65 9.9 3.4 1.5 8.8 2.4 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PP28 PF10252.4 GAP93445.1 - 4.6e-27 93.8 16.9 4.6e-27 93.8 11.7 3.4 3 1 0 3 3 3 1 Casein kinase substrate phosphoprotein PP28 Daxx PF03344.10 GAP93445.1 - 0.013 14.0 33.4 0.015 13.8 23.1 1.1 1 0 0 1 1 1 0 Daxx Family AMP-binding PF00501.23 GAP93446.1 - 1e-73 248.1 0.0 1.9e-73 247.2 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 GAP93446.1 - 2.7e-61 206.6 0.0 3.8e-61 206.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 GAP93446.1 - 3.4e-12 46.3 0.0 6e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 GAP93446.1 - 5.2e-09 36.2 0.1 1.8e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAP93446.1 - 8.3e-06 26.6 0.0 5.7e-05 23.9 0.0 2.5 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 GAP93446.1 - 0.00023 19.9 0.0 0.00055 18.7 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 GAP93446.1 - 0.028 13.3 0.0 0.068 12.0 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein KR PF08659.5 GAP93446.1 - 0.077 12.6 0.1 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 KR domain adh_short PF00106.20 GAP93446.1 - 0.092 12.6 0.2 0.49 10.2 0.1 2.2 1 1 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 GAP93446.1 - 0.12 11.1 0.1 16 4.2 0.0 2.5 3 0 0 3 3 3 0 RmlD substrate binding domain PP-binding PF00550.20 GAP93447.1 - 1.8e-10 40.9 0.1 2.5e-10 40.4 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 GAP93447.1 - 1.7e-05 24.7 0.1 2.2e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Acyl-carrier DUF3235 PF11574.3 GAP93447.1 - 0.32 11.2 3.5 0.1 12.8 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3235) Fer4 PF00037.22 GAP93448.1 - 1.4e-13 49.8 16.5 5.2e-08 32.1 2.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 GAP93448.1 - 6.8e-12 45.5 10.6 1.1e-11 44.9 7.3 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 GAP93448.1 - 6e-10 39.2 8.3 1.1e-09 38.3 5.8 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 GAP93448.1 - 1.1e-09 38.9 7.4 0.0002 22.0 0.3 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 GAP93448.1 - 1.9e-09 37.1 21.9 6.8e-08 32.1 8.4 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 GAP93448.1 - 7e-09 35.4 32.1 1.1e-05 25.2 8.7 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.1 GAP93448.1 - 9.7e-08 31.9 20.3 2e-05 24.5 8.0 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 GAP93448.1 - 1.3e-07 31.1 14.7 0.00043 20.0 1.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 GAP93448.1 - 2.3e-07 30.3 17.1 0.0012 18.6 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 GAP93448.1 - 5e-06 26.4 12.7 0.00056 20.0 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 GAP93448.1 - 5.1e-06 26.7 9.4 0.00067 19.9 7.5 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 GAP93448.1 - 4.8e-05 23.6 9.6 0.014 15.8 0.6 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 GAP93448.1 - 0.0094 16.3 15.3 0.29 11.5 3.2 2.7 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 GAP93448.1 - 0.011 16.2 12.9 0.21 12.1 1.1 2.8 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 GAP93448.1 - 0.069 13.7 16.9 0.15 12.6 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 GAP93448.1 - 0.11 12.6 4.8 0.26 11.4 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain PCMT PF01135.14 GAP93449.1 - 2.5e-36 125.1 0.0 5.1e-34 117.6 0.0 2.1 1 1 1 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 GAP93449.1 - 2.9e-06 26.9 0.0 4.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAP93449.1 - 7.2e-06 26.5 0.0 1.4e-05 25.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAP93449.1 - 7.5e-05 22.7 0.1 0.00028 20.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 GAP93449.1 - 0.0013 18.4 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAP93449.1 - 0.018 14.7 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 GAP93449.1 - 0.023 13.7 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MTS PF05175.9 GAP93449.1 - 0.064 12.6 0.0 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_9 PF08003.6 GAP93449.1 - 0.11 11.1 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Mito_carr PF00153.22 GAP93451.1 - 1.7e-57 191.1 3.2 1.8e-22 78.8 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein DUF2613 PF11021.3 GAP93451.1 - 0.37 10.5 2.6 1.1 8.9 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) DUF2370 PF10176.4 GAP93453.1 - 9.2e-80 267.3 0.0 9.2e-80 267.3 0.0 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF2370) DUF1996 PF09362.5 GAP93454.1 - 6.9e-88 294.2 0.2 9.4e-88 293.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) HET PF06985.6 GAP93455.1 - 2.2e-23 82.9 0.0 6.3e-23 81.4 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HTH_39 PF14090.1 GAP93455.1 - 0.076 12.4 0.9 0.16 11.4 0.6 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Baculo_PEP_C PF04513.7 GAP93457.1 - 0.0013 18.5 1.3 0.0042 16.9 0.9 1.7 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.13 GAP93457.1 - 0.0055 16.2 2.5 0.0055 16.2 1.7 1.7 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain PilJ PF13675.1 GAP93457.1 - 0.0067 16.7 2.2 0.015 15.5 1.5 1.7 1 1 0 1 1 1 1 Type IV pili methyl-accepting chemotaxis transducer N-term DUF2580 PF10824.3 GAP93457.1 - 0.016 15.5 3.0 0.016 15.5 2.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2580) RGCC PF15151.1 GAP93457.1 - 0.022 15.1 1.2 0.13 12.7 0.8 2.2 1 1 0 1 1 1 0 Response gene to complement 32 protein family Tmemb_cc2 PF10267.4 GAP93457.1 - 0.032 12.8 0.2 0.044 12.3 0.1 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Peptidase_M75 PF09375.5 GAP93457.1 - 0.039 13.2 0.1 0.042 13.1 0.1 1.2 1 0 0 1 1 1 0 Imelysin RmuC PF02646.11 GAP93457.1 - 0.088 11.6 1.0 0.13 11.0 0.7 1.3 1 0 0 1 1 1 0 RmuC family IncA PF04156.9 GAP93457.1 - 0.15 11.6 1.7 0.22 11.0 1.2 1.3 1 0 0 1 1 1 0 IncA protein OmpH PF03938.9 GAP93457.1 - 0.32 10.9 1.9 0.46 10.4 1.3 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DASH_Dam1 PF08653.5 GAP93457.1 - 0.46 10.2 2.2 4.4 7.1 0.1 2.7 2 1 0 2 2 2 0 DASH complex subunit Dam1 DUF4404 PF14357.1 GAP93457.1 - 0.47 10.9 4.8 2.7 8.4 2.2 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) Abhydrolase_3 PF07859.8 GAP93458.1 - 1.5e-35 122.6 0.1 1e-34 120.0 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 GAP93458.1 - 3.6e-07 29.2 0.0 5.3e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 GAP93458.1 - 0.009 14.6 0.0 0.44 9.1 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) GMC_oxred_N PF00732.14 GAP93460.1 - 2.6e-27 95.7 0.0 3.5e-21 75.6 0.0 3.2 2 1 1 3 3 3 2 GMC oxidoreductase GMC_oxred_C PF05199.8 GAP93460.1 - 1.6e-25 90.1 0.0 3.3e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAP93460.1 - 2e-05 23.6 0.0 0.0071 15.2 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAP93460.1 - 0.0018 18.2 0.0 0.005 16.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAP93460.1 - 0.0046 16.8 0.1 0.018 14.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAP93460.1 - 0.03 14.3 0.0 1.5 8.8 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAP93460.1 - 0.032 13.2 0.2 0.054 12.5 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.19 GAP93460.1 - 0.034 12.9 0.4 0.23 10.2 0.3 2.0 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 GAP93460.1 - 0.16 10.3 0.3 0.25 9.7 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein ABC_tran PF00005.22 GAP93461.1 - 8.4e-26 90.9 0.0 1.5e-25 90.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 GAP93461.1 - 3.5e-08 32.8 16.6 9.5e-08 31.4 0.5 3.6 3 1 1 4 4 4 2 ABC-2 type transporter DUF258 PF03193.11 GAP93461.1 - 0.00018 20.7 0.2 0.00032 19.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 GAP93461.1 - 0.00027 20.4 0.1 0.008 15.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 GAP93461.1 - 0.0014 18.6 0.3 0.073 13.0 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 GAP93461.1 - 0.016 14.6 1.7 0.039 13.4 1.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 GAP93461.1 - 0.059 13.3 1.6 0.11 12.4 1.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase SbcCD_C PF13558.1 GAP93461.1 - 0.06 13.2 0.3 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.18 GAP93461.1 - 0.062 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Dynamin family FtsK_SpoIIIE PF01580.13 GAP93461.1 - 0.073 12.5 0.2 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 GAP93461.1 - 0.13 11.7 1.5 0.24 10.7 1.1 1.4 1 1 0 1 1 1 0 AAA-like domain ArgK PF03308.11 GAP93461.1 - 0.14 10.9 0.4 0.26 10.0 0.3 1.3 1 0 0 1 1 1 0 ArgK protein IIGP PF05049.8 GAP93461.1 - 0.16 10.7 0.3 0.25 10.0 0.2 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF87 PF01935.12 GAP93461.1 - 1.4 8.6 3.4 2.4 7.9 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 ATP_bind_1 PF03029.12 GAP93461.1 - 1.4 8.3 2.3 2.5 7.5 1.6 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein COX15-CtaA PF02628.10 GAP93462.1 - 2.1e-89 299.3 15.0 2.1e-89 299.3 10.4 2.4 2 1 0 2 2 2 1 Cytochrome oxidase assembly protein Patatin PF01734.17 GAP93463.1 - 3.5e-25 89.1 0.0 9.1e-25 87.7 0.0 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase zf-C3HC4_2 PF13923.1 GAP93463.1 - 1.4e-05 25.0 20.6 0.00025 20.9 3.7 2.9 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) ABC_tran PF00005.22 GAP93463.1 - 0.0014 18.9 0.0 0.0041 17.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 GAP93463.1 - 0.0016 17.6 0.0 0.0053 15.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 zf-C3HC4 PF00097.20 GAP93463.1 - 0.0063 16.1 3.8 0.0063 16.1 2.7 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Zeta_toxin PF06414.7 GAP93463.1 - 0.034 13.2 0.0 0.12 11.4 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.1 GAP93463.1 - 0.037 13.9 0.0 0.11 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAP93463.1 - 0.059 13.5 0.0 0.2 11.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain MMR_HSR1 PF01926.18 GAP93463.1 - 0.078 12.9 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 GAP93463.1 - 0.11 12.0 0.1 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 GAP93463.1 - 0.11 13.2 0.2 1.6 9.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain MobB PF03205.9 GAP93463.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 GAP93463.1 - 0.17 11.6 0.0 0.42 10.4 0.0 1.7 1 0 0 1 1 1 0 Dynamin family DUF87 PF01935.12 GAP93463.1 - 0.18 11.6 0.0 0.5 10.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF87 zf-RING_2 PF13639.1 GAP93463.1 - 0.43 10.4 16.7 0.017 14.9 3.4 2.8 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 GAP93463.1 - 3.2 7.5 18.9 0.031 14.0 3.2 2.8 2 0 0 2 2 2 0 zinc-RING finger domain Ank_2 PF12796.2 GAP93464.1 - 2e-71 236.3 7.1 2.1e-13 50.4 0.2 9.4 5 3 5 10 10 10 9 Ankyrin repeats (3 copies) Ank PF00023.25 GAP93464.1 - 5.4e-47 155.3 17.9 1.2e-06 27.9 0.0 17.7 17 1 1 18 18 18 11 Ankyrin repeat Ank_4 PF13637.1 GAP93464.1 - 2.5e-43 145.6 17.2 1e-06 29.0 0.0 11.2 10 1 1 11 11 11 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP93464.1 - 6.3e-43 143.8 18.9 3.4e-07 30.3 0.0 14.9 7 5 9 16 16 16 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP93464.1 - 5.9e-37 122.0 21.7 0.011 15.8 0.0 18.0 18 1 1 19 19 19 9 Ankyrin repeat DUF3447 PF11929.3 GAP93464.1 - 0.0066 16.2 2.3 14 5.5 0.0 4.9 5 0 0 5 5 5 2 Domain of unknown function (DUF3447) APH PF01636.18 GAP93465.1 - 3.5e-07 30.1 1.4 1.9e-05 24.5 1.0 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAP93465.1 - 0.0015 18.1 1.8 0.011 15.3 0.0 2.8 3 1 1 4 4 4 1 Choline/ethanolamine kinase Ank_2 PF12796.2 GAP93466.1 - 2.6e-84 277.6 2.8 1.4e-14 54.1 0.0 10.6 5 4 6 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.25 GAP93466.1 - 1.2e-56 185.8 23.8 0.00043 19.9 0.0 19.7 21 0 0 21 21 21 11 Ankyrin repeat Ank_4 PF13637.1 GAP93466.1 - 3.3e-50 167.6 15.3 8.5e-07 29.3 0.0 13.5 10 3 4 14 14 14 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAP93466.1 - 2.3e-48 161.1 17.2 3.7e-07 30.1 0.0 15.3 8 5 8 16 16 16 13 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAP93466.1 - 3.9e-45 147.3 13.8 0.035 14.3 0.0 20.5 21 0 0 21 21 21 10 Ankyrin repeat DNA_topoisoIV PF00521.15 GAP93467.1 - 6.3e-120 400.8 0.7 1.2e-119 400.0 0.5 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 GAP93467.1 - 2.3e-31 108.3 0.2 7.6e-31 106.6 0.1 1.9 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 GAP93467.1 - 1.5e-12 47.3 0.0 6.2e-12 45.3 0.0 2.1 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 GAP93467.1 - 2e-09 37.1 0.0 4.8e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Reticulon PF02453.12 GAP93468.1 - 5.9e-39 133.3 1.4 7.8e-39 132.9 1.0 1.1 1 0 0 1 1 1 1 Reticulon I-set PF07679.11 GAP93468.1 - 0.12 12.2 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain RabGAP-TBC PF00566.13 GAP93469.1 - 4.7e-47 160.2 0.0 5.1e-46 156.8 0.0 2.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF1664 PF07889.7 GAP93469.1 - 0.12 12.1 1.3 0.32 10.7 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FUSC PF04632.7 GAP93469.1 - 2.8 6.2 16.8 0.27 9.6 8.0 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein family SPX PF03105.14 GAP93470.1 - 0.0049 16.6 12.2 0.0085 15.9 8.5 1.5 1 0 0 1 1 1 1 SPX domain NARP1 PF12569.3 GAP93470.1 - 1.1 7.8 13.8 2.1 6.9 9.6 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ycf1 PF05758.7 GAP93470.1 - 1.2 6.7 11.4 1.5 6.4 7.9 1.1 1 0 0 1 1 1 0 Ycf1 Plasmodium_Vir PF05795.6 GAP93470.1 - 3.7 6.6 5.9 5.7 6.0 4.1 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Zip PF02535.17 GAP93470.1 - 4.4 6.2 13.4 7.3 5.4 9.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Kei1 PF08552.6 GAP93470.1 - 7.2 6.2 8.3 13 5.3 5.7 1.4 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 TatD_DNase PF01026.16 GAP93471.1 - 3.4e-31 108.3 0.0 5.1e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase VPS9 PF02204.13 GAP93473.1 - 9.4e-14 51.3 0.0 2.8e-13 49.7 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.1 GAP93473.1 - 9.7e-14 51.0 0.2 2.2e-10 40.3 0.0 4.7 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAP93473.1 - 1.5e-10 41.3 0.0 0.00042 20.6 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAP93473.1 - 5.9e-08 32.2 0.4 0.18 12.1 0.0 5.9 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.1 GAP93473.1 - 9.4e-07 29.1 0.4 0.019 15.4 0.0 4.6 4 1 2 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.25 GAP93473.1 - 0.00028 20.5 0.2 0.039 13.7 0.0 4.1 5 0 0 5 5 5 1 Ankyrin repeat PX PF00787.19 GAP93473.1 - 0.0019 17.9 0.1 0.0089 15.8 0.0 2.1 2 0 0 2 2 2 1 PX domain NCU-G1 PF15065.1 GAP93473.1 - 0.0054 15.4 0.0 0.0096 14.6 0.0 1.3 1 0 0 1 1 1 1 Lysosomal transcription factor, NCU-G1 Chal_sti_synt_C PF02797.10 GAP93474.1 - 0.14 12.1 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain Abhydrolase_6 PF12697.2 GAP93475.1 - 8.2e-20 71.6 0.2 2.8e-19 69.9 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAP93475.1 - 7e-09 35.5 0.0 8.9e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAP93475.1 - 0.0066 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 GAP93475.1 - 0.082 13.1 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain Dyp_perox PF04261.7 GAP93476.1 - 2.6e-09 36.2 0.3 5.1e-08 32.0 0.0 2.7 2 1 0 2 2 2 1 Dyp-type peroxidase family CBM_20 PF00686.14 GAP93477.1 - 3.6e-26 90.5 0.0 5.8e-26 89.9 0.0 1.3 1 0 0 1 1 1 1 Starch binding domain TIP120 PF08623.5 GAP93478.1 - 5.8e-62 208.2 5.4 3.4e-60 202.4 0.0 4.5 5 0 0 5 5 5 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 GAP93478.1 - 1.2e-16 60.7 14.5 0.007 16.6 0.0 9.1 8 2 1 9 9 9 5 HEAT repeats HEAT PF02985.17 GAP93478.1 - 7.7e-09 34.9 18.9 0.3 11.2 0.1 9.3 10 0 0 10 10 10 3 HEAT repeat Cnd1 PF12717.2 GAP93478.1 - 4.4e-05 23.3 3.6 0.26 11.1 0.0 5.8 6 3 0 7 7 7 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 GAP93478.1 - 0.00037 20.8 19.9 10 6.7 0.1 9.7 9 2 2 11 11 11 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 GAP93478.1 - 0.0012 19.1 2.7 8.5 6.8 0.0 7.3 8 3 1 9 9 9 1 Vacuolar 14 Fab1-binding region ESAG1 PF03238.8 GAP93478.1 - 0.092 12.0 0.1 4.4 6.5 0.0 2.8 3 0 0 3 3 3 0 ESAG protein Sigma70_ner PF04546.8 GAP93478.1 - 0.16 11.5 6.9 2.6 7.6 3.3 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region NmrA PF05368.8 GAP93479.1 - 1.1e-12 47.6 0.0 1.5e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAP93479.1 - 1.5e-07 31.5 1.4 2.4e-07 30.9 1.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding MIP PF00230.15 GAP93480.1 - 2.8e-48 164.3 16.6 3.4e-48 164.0 11.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein Glyco_hydro_43 PF04616.9 GAP93481.1 - 2.4e-13 49.8 4.3 3.9e-13 49.1 3.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 APH PF01636.18 GAP93482.1 - 5.1e-12 46.0 0.1 8.5e-08 32.2 0.1 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAP93482.1 - 5.9e-06 25.9 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 GAP93482.1 - 0.0021 16.7 0.0 0.0033 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 GAP93482.1 - 0.067 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Kdo PF06293.9 GAP93482.1 - 0.088 11.8 0.0 0.19 10.7 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fructosamin_kin PF03881.9 GAP93482.1 - 0.1 11.5 0.0 0.48 9.3 0.0 1.8 2 0 0 2 2 2 0 Fructosamine kinase UAA PF08449.6 GAP93483.1 - 1.9e-92 309.4 6.1 2.3e-92 309.1 4.3 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 GAP93483.1 - 0.0032 16.6 0.1 0.0032 16.6 0.0 1.6 2 0 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.15 GAP93483.1 - 0.0039 17.2 21.6 0.2 11.7 2.8 3.5 3 0 0 3 3 3 3 EamA-like transporter family EmrE PF13536.1 GAP93483.1 - 0.0087 16.2 16.4 0.033 14.3 2.2 3.1 2 1 1 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 GAP93483.1 - 0.015 14.9 3.9 0.015 14.9 2.7 2.5 2 1 1 3 3 3 0 Triose-phosphate Transporter family WD40 PF00400.27 GAP93484.1 - 2.6e-14 52.4 2.0 0.14 12.0 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Dynamin_M PF01031.15 GAP93485.1 - 1.3e-113 378.7 0.0 2.4e-113 377.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 GAP93485.1 - 3.5e-55 186.3 0.6 9.1e-55 185.0 0.0 2.0 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 GAP93485.1 - 2.4e-31 107.4 5.4 4.5e-31 106.5 0.6 2.7 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 GAP93485.1 - 0.0014 18.5 0.0 0.0049 16.8 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAP93485.1 - 0.02 15.4 0.0 0.051 14.0 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein zf-CCHC_4 PF14392.1 GAP93485.1 - 0.14 11.8 0.1 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle LRR_6 PF13516.1 GAP93486.1 - 5.3e-11 41.4 4.0 0.11 12.6 0.0 6.6 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.2 GAP93486.1 - 4.6e-08 32.4 16.1 0.00083 18.9 0.0 5.4 4 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAP93486.1 - 5.7e-07 28.6 3.3 4.7 7.6 0.1 6.0 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_8 PF13855.1 GAP93486.1 - 9.8e-05 22.0 8.9 1.2 8.9 0.0 4.4 3 2 0 3 3 3 3 Leucine rich repeat LRR_7 PF13504.1 GAP93486.1 - 0.00064 19.4 0.8 74 4.2 0.0 5.4 5 0 0 5 5 5 0 Leucine rich repeat LKAAEAR PF15478.1 GAP93486.1 - 1.2 9.4 4.9 2.2 8.5 0.1 2.6 3 0 0 3 3 3 0 Family of unknown function with LKAAEAR motif MutS_III PF05192.13 GAP93486.1 - 4.3 7.0 8.7 1.2e+02 2.3 0.0 2.9 2 1 0 2 2 2 0 MutS domain III F-box PF00646.28 GAP93487.1 - 0.0025 17.4 0.1 0.0059 16.2 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAP93487.1 - 0.013 15.2 0.0 0.035 13.8 0.0 1.8 1 0 0 1 1 1 0 F-box-like DUF1903 PF08991.5 GAP93488.1 - 1.2e-23 82.9 5.4 1.5e-23 82.7 3.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 GAP93488.1 - 0.016 15.1 4.5 0.027 14.3 3.1 1.4 1 0 0 1 1 1 0 CHCH domain Cmc1 PF08583.5 GAP93488.1 - 0.39 10.5 6.5 0.086 12.6 1.4 1.9 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Nup84_Nup100 PF04121.8 GAP93489.1 - 4.8e-70 236.0 0.0 3.8e-69 233.1 0.0 2.3 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 Mod_r PF07200.8 GAP93490.1 - 5.2e-09 36.1 6.9 2.8e-08 33.7 2.7 2.0 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein Radial_spoke PF04712.7 GAP93490.1 - 0.0085 14.8 0.1 0.011 14.5 0.1 1.1 1 0 0 1 1 1 1 Radial spokehead-like protein Gal4_dimer PF03902.8 GAP93490.1 - 0.016 15.1 0.4 1.7 8.6 0.1 2.4 2 0 0 2 2 2 0 Gal4-like dimerisation domain DUF4360 PF14273.1 GAP93491.1 - 4.7e-26 91.5 0.1 5.8e-26 91.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) zf-C3HC4_2 PF13923.1 GAP93492.1 - 0.00011 22.1 3.4 0.00011 22.1 2.3 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAP93492.1 - 0.00025 20.6 6.6 0.00025 20.6 4.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAP93492.1 - 0.0012 18.6 5.4 0.0012 18.6 3.8 2.4 2 0 0 2 2 2 1 Ring finger domain Abhydrolase_4 PF08386.5 GAP93493.1 - 1.6e-17 63.2 0.0 4.1e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 GAP93493.1 - 1.1e-09 38.2 0.0 2.9e-09 36.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAP93493.1 - 9.6e-05 22.3 0.0 0.001 18.9 0.0 2.5 1 1 0 2 2 2 1 Alpha/beta hydrolase family AalphaY_MDB PF04611.7 GAP93493.1 - 0.099 12.5 0.0 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 Mating type protein A alpha Y mating type dependent binding region